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PRODID:-//Cancer Epigenetics Society - ECPv5.3.2.1//NONSGML v1.0//EN
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X-WR-CALNAME:Cancer Epigenetics Society
X-ORIGINAL-URL:https://ces.b2sg.org
X-WR-CALDESC:Events for Cancer Epigenetics Society
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DTSTART:20190331T010000
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DTSTART:20191027T010000
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DTSTART;VALUE=DATE:20190128
DTEND;VALUE=DATE:20190302
DTSTAMP:20260730T054057
CREATED:20190128T084256Z
LAST-MODIFIED:20190128T084256Z
UID:21036-1548633600-1551484799@ces.b2sg.org
SUMMARY:Post-Doctoral Research Fellow
DESCRIPTION:The Johnston Laboratory (https://johnstonlaboratory.com/) in the Vaccine and Infectious Disease Division at the Fred Hutchinson Cancer Research Center is recruiting a highly motivated and creative Post-Doctoral Fellow to conduct research relating to synthetic microbiology and microbial genetics / epigenetics. The successful candidate will be involved with delineation of the innate genetic defense systems of bacterial species and the design\, development\, and implementation of methodologies to bypass these systems during genetic engineering. This position will be funded under an NIH Director’s Transformative Research Award (TR01) research grant entitled “The SyngenicDNA and µPOET Platform: Overcoming Innate Barriers to Genetic Engineering in Bacteria.” \n\n*Please include a cover letter with your application\, detailing your interest and suitability for this position. \n\n\n\nResponsibilities\n\n\n\nThe Johnston Laboratory is an interdisciplinary and highly collaborative team of classically trained microbiologists\, synthetic microbiologists\, bioinformaticians and engineers. Using cutting edge technologies and methodologies\, we seek to gain a deeper functional understanding of what bacteria are doing and how they are doing it\, and then to use that information to create novel therapeutics and engineer the next generation of microbe-based technologies for application in human medicine\, synthetic microbiology and bioengineering. \n  \nWet-lab: The ideal post-doctoral candidate must have wet-lab experience in molecular biology and the cultivation/genetic manipulation of non-model bacteria (in addition to laboratory strains of E. coli). Hands-on experience with CRISPR-Cas / Transposon mutagenesis / Recombineering techniques (one or multiple) are essential. Experience with bacterial conjugation is also a plus\, but not required. \n  \nDry-lab: The candidate will work closely with a computational informatician in development/curation of a comprehensive database of genetic defense systems in bacteria\, and accordingly dry-lab experience with Linux-based bioinformatic software / data analysis environments (Python/R) is favorable. Familiarity with handling DNA/RNA sequencing data and related programs will be advantageous. \n\n\n\nQualifications\n\n\n\n\nPh.D. in Microbiology\, Molecular biology\, Bioengineering\, or related field.\nProven expertise with genetic engineering of non-model bacteria\nProven understanding and expertise in synthetic biology techniques (CRISPR-Cas / Transposon mutagenesis / Recombineering / Gene editing tools)\nCandidate must demonstrate outstanding personal initiative and creativity in problem solving\nExperience in scientific programming/scripting for analysis of DNA/RNA sequencing data\nExperience with statistical analysis\nExcellent teamwork\, time management and organizational skills\nAbility to work independently in a dynamic and results-oriented environment\nAbility to present data to a multidisciplinary audience in a clear and concise manner\nAbility to meet deadlines and multitask efficiently is a must
URL:https://ces.b2sg.org/event/28jan19/
LOCATION:Fred Hutchinson Cancer Research Center\, 1100 Fairview Ave. N.\, Seattle\, WA\, 98109-1024\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/png:https://ces.b2sg.org/wp-content/uploads/2016/07/fred_hutch.png
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