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PRODID:-//Cancer Epigenetics Society - ECPv5.3.2.1//NONSGML v1.0//EN
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X-WR-CALNAME:Cancer Epigenetics Society
X-ORIGINAL-URL:https://ces.b2sg.org
X-WR-CALDESC:Events for Cancer Epigenetics Society
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DTSTART:20190331T010000
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DTSTART:20191027T010000
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DTSTART;VALUE=DATE:20190529
DTEND;VALUE=DATE:20190701
DTSTAMP:20260729T195449
CREATED:20190529T082757Z
LAST-MODIFIED:20190529T082757Z
UID:21275-1559088000-1561939199@ces.b2sg.org
SUMMARY:Scientist (Biochemistry)
DESCRIPTION:We’re seeking a highly motivated and technically proficient laboratory Scientist with a strong enzymology background to join our dynamic biochemistry team. The successful candidate will provide biochemistry solutions across multiple projects in all therapeutic areas in a high-visibility\, highly-matrixed environment. Creativity\, enthusiasm\, organization\, and excellent communication skills a must. Excellent development and advancement potential. \nJob Responsibilities \n\nConceptual design and execution of novel biochemical assays to kinetically characterize enzyme targets\nDevelop strategies to ensure quality expression\, purification\, and biophysical characterization of enzymes produced from multiple expression systems\nInteract with exploratory cell biologists to help elucidate relevant intracellular biochemistry\, genetic and epigenetic regulation of our targets and advance them through validation\nInteract closely with medicinal chemistry to guide small molecule drug discovery through the execution of inhibitor or activator mechanism of action studies\nDual leadership from bench and in CRO management; manage external FTE resources; transfer and validate assays to external partners\n\nQualifications \n\nPhD in Enzymology\, Biochemistry or related field with 0-5+ years industry research experience or an MS or BS degree with 7-10 years of industry research experience in the context of small-molecule drug discovery\nA strong background in steady-state enzymology with emphasis on mechanism of action and kinetic studies with (UV/VIS\, TR-FRET\, FP) readouts. Past experience with coupled enzyme assay systems\, transient kinetics\, KNIME informatics environment\, and LCMS-based enzyme assays is a plus.\nIn-depth understanding of recombinant protein expression and purification from bacterial\, insect\, and yeast systems.\nA proven history of effective team work with excellent collaborative and communication skills is required
URL:https://ces.b2sg.org/event/29may19/
LOCATION:Agios Pharmaceuticals\, 88 Sidney Street\, Cambridge\, MA\, 02139\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2019/04/agios-pharmaceuticals-inc-logo.jpg
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