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PRODID:-//Cancer Epigenetics Society - ECPv5.3.2.1//NONSGML v1.0//EN
CALSCALE:GREGORIAN
METHOD:PUBLISH
X-WR-CALNAME:Cancer Epigenetics Society
X-ORIGINAL-URL:https://ces.b2sg.org
X-WR-CALDESC:Events for Cancer Epigenetics Society
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TZID:Europe/Paris
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TZOFFSETFROM:+0100
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TZNAME:CEST
DTSTART:20160327T010000
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DTSTART:20161030T010000
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20160419
DTEND;VALUE=DATE:20160423
DTSTAMP:20260729T201716
CREATED:20151229T224217Z
LAST-MODIFIED:20160419T105206Z
UID:12186-1461024000-1461369599@ces.b2sg.org
SUMMARY:3rd Annual Epigenetic  Inhibitor Discovery  - Targeting Histone Methyltransferases\, Demethylases and Bromodomains
DESCRIPTION:Targeting epigenetic modifiers and readers\, particularly histone methyltransferases\, demethylases and bromodomain-containing proteins have recently set the foundation for a new generation of anti-cancer drugs. Over the past few years\, several companies have developed and successfully moved novel compounds targeting EZH2\, DOT1L\, LSD1\, and a collection of BET bromodomain inhibitors into clinical studies. As these compounds continue to progress\, developers are now focused on the discovery of new targets and designing novel inhibitors to expand into this robust target space. Of particular interest for discovery are non-BET bromodomain proteins and methyl lysine readers; arginine methyltransferases; and JmjC-domain containing demethylases. \nCambridge Healthtech Institute will once again convene leaders in Epigenetic Inhibitor Discovery to bring forth novel and emerging strategies for inhibition\, new bioactive tools and inhibitors\, as well as strategies for lead optimization to obtain clinically relevant small molecules.
URL:https://ces.b2sg.org/event/3th-annual-epigenetic-inhibitor-discovery-targeting-histone-methyltransferases-demethylases-and-bromodomains/
LOCATION:Hilton San Diego Resort and Spa\, San Diego\, CA\, United States
CATEGORIES:Meetings
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2015/12/crop-drug.jpg
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