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PRODID:-//Cancer Epigenetics Society - ECPv5.3.2.1//NONSGML v1.0//EN
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X-WR-CALNAME:Cancer Epigenetics Society
X-ORIGINAL-URL:https://ces.b2sg.org
X-WR-CALDESC:Events for Cancer Epigenetics Society
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TZID:Europe/Paris
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DTSTART:20190331T010000
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DTSTART:20191027T010000
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DTSTART;VALUE=DATE:20190507
DTEND;VALUE=DATE:20190609
DTSTAMP:20260729T224210
CREATED:20190507T165553Z
LAST-MODIFIED:20190507T165646Z
UID:21230-1557187200-1560038399@ces.b2sg.org
SUMMARY:Group Leader: Drug Discovery Biology
DESCRIPTION:We are currently seeking a highly motivated and talented Group Leader of Drug Discovery Biology. This individual will be a key team member in the organization co-leading cross functional teams to advance projects from target validation through preclinical development to clinical proof-of-concept studies\, in collaboration with MD Anderson researchers. The ideal candidate should have deep knowledge of cancer biology\, strong translational science skills\, and a proven track record of successfully leading multi-disciplinary small molecule teams from target validation through early clinical development in a biotech or pharmaceutical environment. Building on our unique model of drug discovery\, the group leader will work closely with academic and clinical collaborators to integrate innovative biology with clinical research data to position IACS small molecule assets for clinical success. As a member of our R&D leadership team\, this individual will play an essential project leadership role and will be empowered to provide strategic input to guide portfolio management decisions. \nBy joining the Therapeutics Discovery Division\, you have the opportunity to use your talents to make a direct impact on the lives of our patients. Join us\, and lead our next program from concept to clinic. \nKEY FUNCTIONS: \n1. Lead target and translational biology efforts on multiple IACS drug discovery projects\, leveraging resources from cross functional areas\, to deliver compelling translational data sets to advance IACS drug discovery programs into clinical proof-of-concept trials in distinct patient populations. \n2. Serve on the R&D Leadership team\, providing strategic insight to influence IACS portfolio strategy. \n3. Plan and execute the translational research strategy for one or more targets\, inform on target mechanism of action\, and explore translational hypotheses. \n4. Apply knowledge of pharmacology and biomarker development to enable in vivo assessment of chemical matter and establish pharmacokinetic\, pharmacodynamic\, and efficacy relationships. \n5. Coordinate\, direct and lead a team of successful internal scientists\, and collaborative relationships and alliances with internal and external partners to drive innovation and influence the IACS portfolio. \n6. Contribute to project team through lab based activities. \n7. Resource projects in a flexible manner\, including efficient use of outsourcing. \n8. Secure the intellectual property rights\, including drafting of patent applications. \n9. Complete the necessary documentation for IND- and other regulatory filing\, and for any due diligence or licensing activities. \n10. Represent the Therapeutics Discovery Division externally through presentations at key National/International meetings. \n11. Proactively identify\, evaluate and implement novel technologies to support translational activities. \n12. Supervise\, mentor\, and professionally develop a team of dedicated research and associate scientists. \n\nEducation\nRequired: PhD in one of the natural sciences or related field or Medical degree.\n\nPreferred: PhD\, MD or equivalent degree in Biology\, Cell Biology\, Pharmacology or related field.\n\nExperience\nRequired: Nine years experience of relevant research experience in lab.\n\nPreferred: 7 years of relevant research and management experience beyond post-doctoral research maintaining hands-on experience.\n\n1.Demonstrated ability to lead multidisciplinary project teams\, with experience advancing small molecule assets through discovery into clinical development.\n\n2.Experienced manager of people and projects including demonstrated ability to grow new leaders and delegate key projects appropriately.\n\n3.Extensive knowledge in cancer biology including cell signaling\, metabolism\, epigenetics\, and immune-oncology.\n\n4.Deep understanding of preclinical PK/PD/efficacy relationships as they relate to small molecule drug discovery in oncology; translation of findings to the clinic.\n\n5.Knowledge of preclinical and clinical biomarker discovery and development.\n\n6.Demonstrated ability to function efficiently in a multi-disciplinary team environment\n\n7.Evidence of independent thinking and leadership skills are vital. Ability to work well under pressure and drive projects that impact critical timelines is essential\n\n8.Outstanding written and oral communication and negotiation skills are essential\n\n9.Strong leader with focus and drive to succeed
URL:https://ces.b2sg.org/event/7may19/
LOCATION:MD Anderson Cancer Center\, 1515 Holcombe Blvd\, Houston\, TX\, 77030\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/05/MDAnderson.jpg
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