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PRODID:-//Cancer Epigenetics Society - ECPv5.3.2.1//NONSGML v1.0//EN
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X-WR-CALNAME:Cancer Epigenetics Society
X-ORIGINAL-URL:https://ces.b2sg.org
X-WR-CALDESC:Events for Cancer Epigenetics Society
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TZID:Europe/Paris
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DTSTART:20180325T010000
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DTSTART:20181028T010000
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DTSTART;VALUE=DATE:20180724
DTEND;VALUE=DATE:20180826
DTSTAMP:20260730T000629
CREATED:20180724T180050Z
LAST-MODIFIED:20180724T180404Z
UID:20445-1532390400-1535241599@ces.b2sg.org
SUMMARY:Associate Scientist | Epigenetics
DESCRIPTION:We are seeking a highly motivated\, positive and engaged team player to join our Epigenetic Discovery group. The successful candidate will work on drug discovery projects focused on Epigenetic and Transcriptional targets. Specifically\, the candidate will be expected to design\, develop and execute experiments that include new target validation\, identification of biomarkers\, elucidation of mechanism of action\, executing existing cell based assays\, and evaluating regular lists of chemical matter to support ongoing SAR efforts. Experience with chromatin IP (ChIP) is highly desired. In addition\, the candidate will assist in creating stable cell lines\, and developing and optimizing new cell based assays to support drug discovery efforts. \nResponsibilities will include\, but are not limited to\, the following \n\nIndependently design\, plan and execute scientific experiments\nAnalyze and interpret scientific data\, troubleshoot and suggest new directions\nConduct routine assays to confirm hits from primary screens and support ongoing SAR efforts\nDevelop\, trouble shoot and optimize new cell based biomarker and functional assays\nAccurately maintain written reports and organize data\nPresent projects in team\, department and project review meetings\nIndependently review current literature pertaining to oncology\, epigenetics\, transcriptional regulation and related assays\n\nExperience/Skills/Knowledge Required \n\nMaster’s degree in a scientific discipline with at least 6 years work experience\, or Bachelor’s degree with at least 8 years work experience.\nIn-depth knowledge of cancer biology and epigenetics\nFamiliarity with drug discovery process for epigenetic and transcriptional targets in oncology\nExperience with target ID / validation efforts\nExperience in executing and developing cell-based assays\, and small molecule hit confirmation efforts\nExperience in molecular and cell biology techniques including cell culture\, transfection and transduction techniques (overexpression\, RNAi\, CRISPR)\, stable cell line generation/validation\, viability assays\, functional/phenotypic assays such as viability and apoptosis in 2D and 3D settings\, real time PCR\, protein assays such as immunoblotting and/or protein simple\, RNA assays including qPCR and/or Nanostring\, microscopy. Experience in ChIP assays is desired\nHighly motivated\, positive\, capable of multitasking\, attention to detail\, and innovative\nExcellent time management and organizational skills\, strong written and oral communication skills\, ability to think creatively and solve problems are essential
URL:https://ces.b2sg.org/event/celgene-24jul18/
LOCATION:Celgene San Francisco\, 1500 Owens St\, CA\, 94158\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/png:https://ces.b2sg.org/wp-content/uploads/2017/08/celgene-1-e1503843775806.png
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