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PRODID:-//Cancer Epigenetics Society - ECPv5.3.2.1//NONSGML v1.0//EN
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X-WR-CALNAME:Cancer Epigenetics Society
X-ORIGINAL-URL:https://ces.b2sg.org
X-WR-CALDESC:Events for Cancer Epigenetics Society
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TZID:Europe/Paris
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TZOFFSETFROM:+0100
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TZNAME:CEST
DTSTART:20170326T010000
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DTSTART:20171029T010000
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20170501
DTEND;VALUE=DATE:20170522
DTSTAMP:20260819T223316
CREATED:20170518T194136Z
LAST-MODIFIED:20170519T052614Z
UID:18035-1493596800-1495411199@ces.b2sg.org
SUMMARY:Postdoctoral Fellow
DESCRIPTION:Job Description\nThe Hackett Group is looking for a highly talented postdoctoral researcher to lead an exciting project on epigenetic inheritance in mammalian models. \nResearch in the group is focused on understanding epigenetic mechanisms of genome regulation and transgenerational epigenetic inheritance. Other streams of research cover (epi)genomics analyses of embryonic stem cells and the germline cycle\, and development of epigenetic editing technologies (www.embl.it/research/unit/hackett). \nQualifications and Experience\nYou hold a PhD and have a proven track record in epigenomics\, molecular biology and/or developmental biology\, combined with a strong desire to work on fundamental research questions. Specific experience with epigenetics\, mouse biology or bioinformatics would be a strong plus.  \nThe ideal candidate has strong initiative and ability to independently drive a project forward\, a desire to break new ground with their research\, and is keen to work in a collaborative international environment. \nApplication Instructions\nTo apply please submit a covering letter clearly stating your motivation and future research interests/plans\, and a CV with at least two referees\, through our online system \nwww.embl.org/jobs
URL:https://ces.b2sg.org/event/postdoc-fellow-embl/
LOCATION:EMBL Monterotondo\, Via Ercole Ramarini\, 32\, Monterotondo\, 00015\, Italy
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/05/embl-logo-e1525286820407.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170502
DTEND;VALUE=DATE:20170603
DTSTAMP:20260819T223316
CREATED:20170502T180455Z
LAST-MODIFIED:20170505T115918Z
UID:17775-1493683200-1496447999@ces.b2sg.org
SUMMARY:Postdoctoral Research Fellow - Cancer Genetics and Epigenetics
DESCRIPTION:A postdoctoral position is available in the lab of David MacPherson. The position will be funded by a newly awarded R01\, with a focus on the role of key chromatin regulators in driving small cell lung cancer (SCLC)\, an aggressive neuroendocrine tumor type. Cell based screens\, genetic mouse models and study of patient derived tumors and xenografts will be employed in the research project.  The position is ideally suited to candidates interested in understanding at a molecular level how perturbation of chromatin regulators promotes SCLC and also how mutations in chromatin regulators confer vulnerabilities that can be exploited in the design of more effective therapeutics for SCLC. \n\n\n\n\n\n\nCandidates should have a PhD and/or MD\, one or more first author publications\, and experience in molecular and/or cell biology.  Expertise in chromatin biology\, genomic analyses\, mouse genetics\, and/or experience with cell based functional screens would all be looked upon favorably.  Candidates should be independent but also highly collaborative. \n\nAt Fred Hutchinson Cancer Research Center\, home to three Nobel laureates\, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent\, diagnose and treat cancer\, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy\, which harnesses the power of the immune system to treat cancer. An independent\, nonprofit research institute based in Seattle\, Fred Hutch houses the nation’s first and largest cancer prevention research program\, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network.
URL:https://ces.b2sg.org/event/postdoc-fred-hutch/
LOCATION:Fred Hutchinson Cancer Research Center\, 1100 Fairview Ave. N.\, Seattle\, WA\, 98109-1024\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/png:https://ces.b2sg.org/wp-content/uploads/2016/07/fred_hutch.png
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170503
DTEND;VALUE=DATE:20170604
DTSTAMP:20260819T223316
CREATED:20170502T185227Z
LAST-MODIFIED:20170505T115812Z
UID:17780-1493769600-1496534399@ces.b2sg.org
SUMMARY:Postdoctoral Positions - Gene Regulation\, Epigenetics and/or Cancer Biology
DESCRIPTION:Postdoctoral associate positions available for highly motivated candidates with a fresh PHD training in molecular & cell biology\, cancer biology and/or biochemistry to join the Lineberger Comprehensive Cancer Center\, the Department of Biochemistry & Biophysics\, University of North Carolina at Chapel Hill (UNC) School of Medicine\, USA. Those with a strong publication track record are also potentially eligible for a two-year postdoctoral fellowship program available from UNC Cancer Center Postdoc Trainee programs (eligibility: 1\, within less than 1-2 years since completion of PHD training; 2\, US citizen or permanent resident). \nOur laboratory emphasizes on mechanistic understandings of gene regulation\, chromatin biology\, stem cells\, and human disease\, notably cancer (see our recent publications at Molecular Cell 2013\, Blood 2015\, Cell Reports 2015; Cancer Cell 2016). Multiple on-going projects include (1) biochemical characterization of novel factors/complexes that recognize the novel chromatin modifications; (2) CRISPR/dCas9-based editing of epigenomic modifications for understanding the epigenetic pathways in gene expression; (3) knockout and knock-in mouse models with deficiency in histone methylation regulation in context of development and tumorigenesis\, with a special focus on hematopoietic cancer and disease; (4) epigenomic and transcriptome analyses (ChIP-Seq and RNA-Seq) of normal versus cancer cells to delineate pathways essential for tumor growth. \nThe salary of postdoc positions meets new federal Fair Labor Standards Act (FLSA) with a minimum salary of $47\,476 annually. Applicants should be self-motivated with a track record of publication in the above area\, have laboratory and analytical skills\, and be a critical thinker. Application shall include CV\, a cover letter (with summary of research experiences and future interests\, and expected availability date) reprints of publications\, and contact information of three references. The application materials should be sent to gregwang.unc@gmail.com. \nThe University of North Carolina at Chapel Hill is an equal opportunity and affirmative action employer.
URL:https://ces.b2sg.org/event/postdoc-epigenetics-cancer-bio/
LOCATION:University of North Carolina – UNC-Chapel Hill\, Chapel Hill\, NC\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/png:https://ces.b2sg.org/wp-content/uploads/2016/07/U_North_Carolina-2.png
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170503
DTEND;VALUE=DATE:20170604
DTSTAMP:20260819T223316
CREATED:20170503T081626Z
LAST-MODIFIED:20170505T120129Z
UID:17783-1493769600-1496534399@ces.b2sg.org
SUMMARY:Postdoctoral Researcher – Structural Biology
DESCRIPTION:The laboratory of Dr. Ernst Schonbrunn at Moffitt Cancer Center is seeking a postdoctoral researcher to work on inter-disciplinary projects towards the structural biology of proteins as drug targets. The position provides exciting opportunities for structural\, biochemical and cell-based studies of various drug-target interactions and the rational design of new inhibitors with potential as therapeutics. We work in team with medicinal chemists\, biologists and clinicians on the targeting of proteins involved in signaling and epigenetic events. \nThe successful candidate is a highly motivated individual with a PhD or equivalent degree in Biochemistry\, Chemistry or related field. Demonstrated expertise in protein crystallography and biochemical/biophysical characterization of proteins is required.  Candidates must be enthusiastic with excellent organizational skills and effective at working independently\, while also collaborating and assisting the team in its collective research goals. Attention to detail and ability to work on multiple projects is required. Excellent verbal and written communication skills are required.  \nThe Moffitt Cancer Center is a modern research facility on the University of South Florida Campus that conducts research on various aspects of Cancer Biology. The research environment includes state of the art core facilities to support basic research. Please apply online at www.moffitt.org/careers to REQ ID 21506 and send cover letter\, CV and the names and contact information of three references via email to ernst.schonbrunn@moffitt.org. \nMoffitt Cancer Center is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race\, color\, religion\, sex\, sexual orientation\, gender identity\, national origin\, age\, or protected veteran or disabled status. We seek candidates whose skills\, and personal and professional experience\, have prepared them to contribute to our commitment to diversity and excellence.  \n 
URL:https://ces.b2sg.org/event/postdoc-researcher-structural-bio/
LOCATION:Moffitt Cancer Center Magnolia Campus\, 12902 USF Magnolia Drive\, Tampa\, FL\, 33612\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/05/Moffitt-1.jpg
ORGANIZER;CN="Ernst%20Schonbrunn":MAILTO:ernst.schonbrunn@moffitt.org
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170503
DTEND;VALUE=DATE:20170604
DTSTAMP:20260819T223316
CREATED:20170503T084135Z
LAST-MODIFIED:20170505T120239Z
UID:17789-1493769600-1496534399@ces.b2sg.org
SUMMARY:Postdoctoral Fellow - Molecular Oncology
DESCRIPTION:A postdoctoral position is available in the laboratory of Dr. Florian Karreth at the Moffitt Cancer Center. The Karreth lab combines innovative mouse modeling approaches with molecular biology and biochemistry techniques to better understand the crosstalk between oncogenic signaling and non-coding RNAs in the development\, progression\, and resistance of cancer. \nWe are particularly interested in identifying and characterizing protein-coding and non-coding genes that cooperate with oncogenic MAPK signaling to promote tumor progression and drug resistance\, with an emphasis on melanoma. Moreover\, we are studying the oncogenic functions of lncRNAs in ovarian cancer. For more information visit our lab website at http://labpages2.moffitt.org/karreth. \nWe seek a talented and dedicated individual with an interest in characterizing proteins that promote the progression and drug resistance of melanoma.   \nCandidates must demonstrate excellent communication skills\, have a proven track record of scientific productivity\, and be able to work collaboratively in a team.   Experience in mouse modeling and/or oncogenic signaling is highly desirable.   We also seek a talented and dedicated individual with an interest in understanding how ovarian cancer risk SNPs affect lncRNAs expression and function. \nSuccessful candidates will work independently and collaboratively\, design and execute experiments\, and analyze and interpret data. He/She will present his/her findings to the lab during weekly lab meetings\, to the Moffitt community at research-in-progress meetings\, and to the international community at conferences. He/She will author grants and manuscripts\, and mentor students. \nPh.D. or M.D.\, preferably not received more than two years ago. \nThe outstanding research environment includes a new dedicated research building\, state-of-the-art core facilities (e.g. Molecular Genomics\, Flow Cytometry\, Proteomics\, Microscopy\, Transgenic)\, a modern vivarium\, and access to clinical material. A competitive salary and benefits package will be offered to the successful candidate. Interested applicants should email a letter describing their interest and previous experience as well as a CV including the names and contact information of three references to florian.karreth@moffitt.org. \nThe H. Lee Moffitt Cancer and Research Institute is a modern facility in Tampa\, Florida.  We strive to be the leader in understanding in the complexity of cancer through team science and applying those insights for human benefits.  Be part of the cure by joining Moffitt’s team of 800 research faculty scientists\, career staff scientists\, postdocs\, graduate students and support staff dedicated to cancer research. \n 
URL:https://ces.b2sg.org/event/postdoc-molecular-oncology/
LOCATION:Moffitt Cancer Center Magnolia Campus\, 12902 USF Magnolia Drive\, Tampa\, FL\, 33612\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/05/Moffitt-1.jpg
ORGANIZER;CN="Florian%20Karreth":MAILTO: florian.karreth@moffitt.org.
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170504
DTEND;VALUE=DATE:20170605
DTSTAMP:20260819T223316
CREATED:20170504T084233Z
LAST-MODIFIED:20170505T115446Z
UID:17817-1493856000-1496620799@ces.b2sg.org
SUMMARY:Research Associate - Epigenetics
DESCRIPTION:To enable Guardant Health to lead the disruption of cancer treatments through non-invasive cancer screening\, the Technology Development Team is seeking a highly motivated Research Associate to help develop\, test\, and improve sample preparation technologies for rare variant and epigenetic studies with next-generation sequencing. At Guardant\, we leverage the most advanced technologies and work with leaders in many different fields to create the most impactful and meaningful technologies for cancer management. \nAs a Research Associate supporting product and technology development\, you will work with members within the team and interface with multiple teams including process engineering\, clinical operations\, research operations\, and bioinformatics. You will be hands on in the lab and be required to design\, implement\, and validate new technologies related to liquid biopsy sequencing assays for the early detection\, treatment\, and monitoring of all cancer types. \nRESPONSIBILITIES \n\nOperate next generation sequencing instruments\nRun sequencing sample preparation assays in medium to high throughput environment\nTest and improve new sequencing sample preparation assays\nLog and track research samples throughout sequencing workflow\nMaintain appropriate inventory of lab supplies\nBring a can do attitude to solve new and challenging problems in a high pace environment\nAnalyze data and troubleshoot issues within the tech dev team and among other teams\nCollaborate with all functions within project teams\nEngage in early design of products and perform experiments both independently and under the supervision of Senior team members within Tech Dev and Bioinformatics groups\nBe able to present updates\, write reports and SOPs\, and contribute to technical discussions\n\nABOUT YOU \n\nThe ability to handle biological samples (i.e. tissue\, biofluid\, etc.) is a must\nExcellent written and oral communication skills is a must\nProfessional hands-on experience in industrial setting in genomics field is a plus (operational experience is preferred)\nHands-on experience in running sequencing platforms and assays is a plus\n\nGuardant Health develops breakthrough diagnostic technologies to improve cancer management. With Guardant360\, we offer real-time\, biopsy-free tumor sequencing that tracks tumor genomics in real-time and identifies associated treatment options. The recent introduction of groundbreaking analytical tools\, including our Tumor Response Map and a mobile-enabled physician portal\, further advance Guardant Health’s momentum. \nGuardant Health has raised almost $200M from OrbiMed\, Sequoia Capital\, Khosla Ventures\, Lightspeed Venture Partners\, and Formation8\, and is led by a seasoned management team of thought leaders and successful serial entrepreneurs in next generation sequencing and rare cell diagnostics. They are advised by an oncologist-led medical steering committee from leading cancer centers.
URL:https://ces.b2sg.org/event/research-associate-epigenetics-gh/
LOCATION:Guardant Health\, 505 Penobscot Dr.\, Redwood City\, CA\, 94063\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/05/guardant-health.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170504
DTEND;VALUE=DATE:20170605
DTSTAMP:20260819T223316
CREATED:20170504T170124Z
LAST-MODIFIED:20170505T115403Z
UID:17822-1493856000-1496620799@ces.b2sg.org
SUMMARY:Postdoc Position - Investigator\, Medicinal Chemistry
DESCRIPTION:Basic qualifications: \n • PhD degree in Organic Chemistry\, or Medicinal Chemistry.\n• 0 to 3 years of professional and/or industrial experience.\n• High level of synthetic chemistry expertise allowing one to plan synthetic routes to\, and prepare molecules of interest to advance lead optimization efforts.\n• Well versed in the application of new synthetic methodology.\n• High level of scientific credibility as demonstrated through peer-reviewed publications\, presentations\, or patents. \nPreferred qualifications: \n • Post-doc\n• Demonstrated autonomy in decision making.\n• Ability to excel in a team environment and work efficiently in an open-plan laboratory.\n• Excellent written and oral communication skills. \nDetails: \n The successful applicant will join a highly motivated medicinal chemistry team within Oncology Research & Development where the focus will be on progressing hit series through to candidate selection against Epigenetic targets.  The successful applicant will have opportunities to design and implement insightful and creative medicinal chemistry strategies to fulfill these objectives. The applicant will be expected to develop a deep expertise in lead optimization tactics including state-of-the-art synthesis\, purification\, and computational tools. \nPlease note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license\, GSK may be required to capture and report expenses GSK incurs\, on your behalf\, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information\, please visit GSK’s Transparency Reporting For the Record site.
URL:https://ces.b2sg.org/event/postdoc-med-chem-gsk/
LOCATION:gsk\, 1250 S Collegeville Rd\, Collegeville\, PA\, 19426\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/05/GSK.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170504
DTEND;VALUE=DATE:20170605
DTSTAMP:20260819T223316
CREATED:20170504T172327Z
LAST-MODIFIED:20170504T172701Z
UID:17825-1493856000-1496620799@ces.b2sg.org
SUMMARY:Senior Scientific Researcher - Molecular Biology
DESCRIPTION:The Position\nWe are seeking a Senior Scientific Researcher in the Department of Molecular Biology to assist with the development of an advanced cell-based molecular genetics platform. She/he will utilize and create diverse nucleic-acid-based technologies for targeted manipulation of primary and immortalized cells\, with the ultimate goal of improving upon in vitro disease models and approaches for scalable functional genomic screening. The candidate will be expected to work creatively and independently within a dynamic\, highly collaborative research environment. \nWho You Are\nA self-motivated candidate with a PhD in Genetics\, Molecular Biology\, Biochemistry\, Cancer Biology\, or a related discipline. Qualified candidates will have a skillset demonstrating successful application of gene expression analyses and genetic manipulation either in cell-based systems or model organisms. Preferred expertise includes some or all of the following: molecular cloning\, RNA/DNA/protein quantification\, 2D and 3D cell culture\, primary and/or stem cell models\, genome engineering\, epigenetics\, and viral vector development/use. Working knowledge of pooled vector-based screening\, Next-Gen Sequencing (NGS)\, biostatistics\, and/or basic bioinformatics is strongly desired. The successful candidate will be highly organized\, and have excellent communication skills\, both written and verbal. \nWho We Are\nA member of the Roche Group\, Genentech has been at the forefront of the biotechnology industry for more than 40 years\, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work. \nThe next step is yours. To apply today\, click on the “Apply online” button. \nGenentech is an equal opportunity employer & prohibits unlawful discrimination based on race\, color\, religion\, gender\, sexual orientation\, gender identity/expression\, national origin/ancestry\, age\, disability\, marital & veteran status. For more information about equal employment opportunity\, visit our Genentech Careers page.
URL:https://ces.b2sg.org/event/sen-researcher-mol-bio-genentech/
LOCATION:Genentech\, 1 DNA Way\, South San Francisco\, CA\, 94080\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/05/genentech-logo.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170505
DTEND;VALUE=DATE:20170606
DTSTAMP:20260819T223316
CREATED:20170505T073927Z
LAST-MODIFIED:20170505T115245Z
UID:17828-1493942400-1496707199@ces.b2sg.org
SUMMARY:Research Associate II – Leukemia Lab
DESCRIPTION:A Research Associate II position is available in the Leukemia Research Laboratory of Gehr Family Center for Leukemia Research and the Beckman Research Institute of City of Hope. \nThe Center is supported by outstanding core facilities including\, but not limited to\, a large human and mouse leukemia tissue bank\, and GMP facilities for new drug development and exceptional Sequencing and Bioinformatics services. Our long-term goal is to elucidate the mechanisms of leukemogenesis and drug resistance of primitive leukemia cells\, and to identify novel therapeutic approaches in blood cancers. Our current research efforts are directed towards understanding the molecular and cellular pathways underlying the pathogenesis of acute myeloid leukemia (AML) using a combination of genetics\, genomics\, biochemistry\, proteomics\, molecular biology and cellular biology approaches. Our experimental systems include both genetic mouse models and primary leukemia stem cells from AML patients. The focus of this position is to understand the role of epigenetic changes in leukemia development\, progression and maintenance. \nPlease include a cover letter stating research interests and experiences\, curriculum vitae\, and names and contact information of three references. \nMinimum Education and Skills Required for Consideration: \n\nBachelor’s degree in biomedical related fields plus two years related research/laboratory experience.\nMaster’s degree in biomedical related fields preferred plus one year related research/laboratory experience preferred.\nMust be highly motivated with excellent organization and communication skills.\nCandidates with skills in molecular biology\, biochemistry\, tissue culture\, flow cytometry\, gene transfer\, mouse handling and transplantation techniques are preferred.\n\nAbout City of Hope \nCity of Hope\, an innovative biomedical research\, treatment and educational institution with over 4000 employees\, is dedicated to the prevention and cure of cancer and other life-threatening diseases and guided by a compassionate\, patient-centered philosophy. Founded in 1913 and headquartered in Duarte\, California\, City of Hope is a remarkable non-profit institution\, where compassion and advanced care go hand-in-hand with excellence in clinical and scientific research. City of Hope is a National Cancer Institute designated Comprehensive Cancer Center and a founding member of the National Comprehensive Cancer Network\, an alliance of the nation’s 20 leading cancer centers that develops and institutes standards of care for cancer treatment. \nCity of Hope is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race\, religion\, color\, national origin\, sex\, sexual orientation\, gender identity\, age\, status as a protected veteran\, or status as a qualified individual with disability.
URL:https://ces.b2sg.org/event/research-associate-ii-leukemia-lab/
LOCATION:Beckman Research Institute\, 1500 E Duarte Rd.\, Duarte\, CA\, 91741\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/png:https://ces.b2sg.org/wp-content/uploads/2017/02/City-of-hope.png
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170505
DTEND;VALUE=DATE:20170606
DTSTAMP:20260819T223316
CREATED:20170505T112515Z
LAST-MODIFIED:20170511T063443Z
UID:17829-1493942400-1496707199@ces.b2sg.org
SUMMARY:Postdoctoral Fellow- Oncology
DESCRIPTION:We seek a driven and accomplished postdoctoral fellow to join the cancer epigenetics group within the Oncology R&D (ORD) unit of Pfizer’s Worldwide R&D (WRD) division in La Jolla\, California. The successful candidate will collaborate with our cancer-immunopharmacology group to study the roles of epigenetic enzymes in anti-tumor immune responses. Guided by experienced mentors with strong academic track records\, the successful candidate will study fundamental questions in cancer immunology with the ultimate goal of publication in major scientific journals. Thus\, a strong scientific background with relevant expertise and documented accomplishments including significant publications is required. In addition\, the successful candidate will have a strong interest in translating results into novel immunotherapies for cancer. He/she will be highly self-motivated with a sense of urgency and focus on important problems. While driven to make strong individual contributions\, the successful candidate will also enjoy a highly interactive\, team-oriented environment and thrive by taking advantage of the significant multi-disciplinary resources available at Pfizer. This will be facilitated by the candidate’s excellent communication and interpersonal skills\, which complement strong work ethics and overall scientific excellence. \nResponsibilities \nPrimary Duties: \n\nWork independently and as part of teams to conceive\, design\, execute\, analyze/interpret\, and refine experiments ranging from biochemical and molecular assays\, in vitro and in vivo immunological functional assays in model systems\, and clinical sample analysis. Specific duties to include:\nContribute intellectually and at the bench to the conception\, design\, execution\, analysis\, interpretation and internal or external presentation of studies of epigenetic modulators of the anti-tumor immune response.\nKeep abreast with the literature and internal developments to become an expert point of contact for colleagues in the field of epigenetic immunopharmacology\nIndependently\, but with guidance by experienced mentors\, develop results into compelling stories for publication in major scientific journals and presentations on major scientific meetings and conferences\, both internally and externally\nApply genetic and pharmacologic approaches to modulate targets in vitro and in vivo to assess functional impacts on tumor cells and immune cells\, and on anti-tumor immune responses in syngeneic xenograft models and genetically engineered mutant mouse models of cancer. This will include CRISPR\, RNAi\, viral vector delivery\, transfection\, antibodies\, small molecules and other pharmacologic approaches to modulate targets.\nExecute secondary assays across various technology platforms – qRT-PCR\, immunoprecipitation\, ChIP-seq\, ATAC-seq\, FACS\, immunofluorescence\, western blotting\, ELISA\, high content screening\, etc.\nDevelop and apply complex in vitro assays for exploring target biology in tumor cells versus immune cells including T-cell functional assays\, co-culture assays\, ect.\nCollaborate with computational biology groups to analyze data including ChIP-seq\, RNA-seq\, ATAC-seq to support mechanism of action studies.\nEmploy computational and proteomic methods for tumor neoantigen prediction and functional validation\nUse electronic data capture/analysis tools such as Excel\, GraphPad\, Biobook\, Spotfire and PowerPoint for experimental documentation and data analysis/presentations.\nPresent research results and methodologies at weekly meetings with immediate supervisor and/or project leader\, and at meetings with members of the oncology research unit as appropriate.\nContribute to building a culture that embraces scientific excellence\, urgency\, partnerships with key stakeholders\, continuous learning and improvement\, increasing technical skill base and cancer biology expertise; take a proactive role in personal growth and scientific development.\n\nQualifications \nEducation and Experience: \n\nPh.D. in Cell Biology\, Molecular Biology\, or Immunology (or a comparable biological science) with a track record of scientific accomplishment as exemplified by significant scientific publications\nExperience with devising and implementing in vitro and in vivo immunological functional assays\nExperience in immuno-oncology and/or chromatin biology/epigenetics is desirable\nExperience in nucleic acid and protein extraction techniques and downstream analyses including quantitative RT-PCR\, immunoprecipitation (including ChIP)\, and immunoblotting.\nExperience with computational tools for antigen prediction\, NGS experiment design and data analyses\, including epigenomic data\, is desired\nAbility to work in a team environment; excellent written and oral communication skills in English; strong presentation skills and ability to discuss data at project team meetings.\nAble to master new concepts and techniques quickly.\nStrong attention to detail and organizational skills to manage projects in parallel\n\nPHYSICAL/MENTAL REQUIREMENTS: \nLifting\, sitting\, standing\, walking\, bending\, ability to perform mathematical calculations\, ability to read\, comprehend and process complex scientific matter\, and perform complex data analysis. Ability to travel by air\, water and ground. \nNON-STANDARD WORK SCHEDULE\, TRAVEL OR ENVIRONMENT REQUIREMENTS: \nAbility to accommodate non-standard work schedules due to experimental regimen or travel. Ability to adhere to safe work practices and wear full personal protective equipment. Ability to travel nationally and internationally. \nA career at Pfizer offers opportunity\, ownership and impact. All over the world\, Pfizer colleagues work together to positively impact health for everyone\, everywhere. Our colleagues have the opportunity to grow and develop a career that offers both individual and company success; be part of an ownership culture that values diversity and where all colleagues are energized and engaged; and the ability to impact the health and lives of millions of people. Pfizer\, a global leader in the biopharmaceutical industry\, is continuously seeking top talent who are inspired by our purpose to innovate to bring therapies to patients that significantly improve their lives. \nPfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race\, color\, religion\, sex\, sexual orientation\, age\, gender identity or gender expression\, national origin\, disability or veteran status. Pfizer also complies with all applicable national\, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.
URL:https://ces.b2sg.org/event/postdoc-oncology-pfizer/
LOCATION:Pfizer – La Jolla\, CA\, 10350 N Torrey Pines Rd\, La Jolla\, CA\, 92037\, United States
CATEGORIES:Jobs
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170506
DTEND;VALUE=DATE:20170607
DTSTAMP:20260819T223316
CREATED:20170506T044808Z
LAST-MODIFIED:20170506T072719Z
UID:17835-1494028800-1496793599@ces.b2sg.org
SUMMARY:Postdoc - epigenetic research
DESCRIPTION:A postdoctoral position is immediately available at the Vanderbilt University Genetics Institute and Department of Biochemistry. Our group is interested in the role of non-coding sequence variation in complex disease. Research in the Hodges Lab strives to understand how epigenetic features shape human genomes.  \nOur work aims to dissect the relationship between DNAmethylation and gene regulation\, particularly with respect to the gene regulatory activity of non-coding functional elements. We study this relationship on two levels; first\, we are interested in how DNA methylation states are established in differentiating cells. Second\, we are interested in the relationship between genotype and DNA methylation state (epitype). Projects in our lab address these questions utilizing innovative biochemical\, functional genomic and bioinformatic approaches. \nThe desired candidate should have a recent PhD in biochemistry\, genetics or related discipline\, with a strong molecular biology background. Experience with next-generation sequencing\, statistical genetics\, and bioinformatics is a priority. Please send CVs along with contact information for three references to emily.hodges@vanderbilt.edu.
URL:https://ces.b2sg.org/event/postdoc-gen-vanderbilt/
LOCATION:Vanderbilt University Genetics Institute and Department of Biochemistry\, 673B Light Hall\, Nashville\, TN\, 37205\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/png:https://ces.b2sg.org/wp-content/uploads/2017/05/venderbilt-u.png
ORGANIZER;CN="Emily%20Hodges":MAILTO:emily.hodges@vanderbilt.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170506
DTEND;VALUE=DATE:20170607
DTSTAMP:20260819T223316
CREATED:20170506T070545Z
LAST-MODIFIED:20170509T075251Z
UID:17839-1494028800-1496793599@ces.b2sg.org
SUMMARY:Research assistant II - prostate cancer epigenetics
DESCRIPTION:An exciting opportunity has been created for an experienced researcher to join the Alumkal Laboratory at the OHSU Knight Cancer Institute as a Research Assistant 2 in Portland\, OR. The individual will work with Dr. Joshi Alumkal\, Co-Leader of the OHSU Prostate Cancer Research Program.  Our laboratory focuses on identifying mechanisms by which key chromatin modifying enzymes and chromatin readers drive transcription of pathways that promote treatment resistance. We use genomics studies in prostate cancer clinical samples and prostate cancer cell line model systems and functional studies to understand this process. Our goal is to develop new\, targeted treatment strategies for men with advanced prostate cancer. \nThe Research Assistant 2 will be responsible for carrying out experiments in the laboratory\, helping with ordering supplies\, and participating in research to study cancer epigenetics and drug resistance in prostate cancer. Their duties will also include performing mouse xenograft tumor growth experiments with drug injections or drug gavage\, basic molecular biology techniques including cell culture\, DNA/RNA/protein extraction\, QPCR\, Western blots\, maintaining meticulous records of experimental procedures\, and preparing material for presentation and/or submission to peer reviewed publications. \nRequired Qualifications: \n\nBachelor’s degree with major courses in field of research and no experience\, Or an AA/RN and 2 years of experience\nAbility to prioritize multiple tasks at one time\nExcellent verbal and written communication skills\nExcellent analytical and organizational skills\nAbility to work independently and as part of a team while being collaborative in resolving problems\nProficient with computers running Windows software such a MS Excel\, Access\, Word and PowerPoint\nExcellent customer service skills both on the phone and in person\nEnergy and drive to coordinate multiple projects simultaneously\nAbility to use tact and diplomacy to maintain effective working relationships\nWorking knowledge of basic molecular biology techniques: PCR\, DNA/RNA extraction\nProficiency with mammalian cell culture\nAble to perform the essential functions of the position with or without accommodation\n\nPreferred Qualifications: \n\n2 years of experience in a molecular biology setting\nExpertise with recombinant DNA techniques\, Western blots\, and RNAi/plasmid transfections\nRodent handling experience\, especially with xenograft tumor growth experiments involving injection and/or gavage treatment\n\nWork schedule\, hours\, salary range and FTE: \n\nFTE: 1.0 FTE\, Full Time\nSchedule: Monday – Friday\, with occasional night and weekend hours\nSalary Range: $30\,638 – $40\,000\nLocation: Portland\, OR (South Waterfront)\nJob Type: Research\n\nOregon Health & Science University values a diverse and culturally competent workforce. We are proud of our commitment to being an equal opportunity\, affirmative action organization that does not discriminate against applicants on the basis of any protected class status\, including disability status and protected veteran status. Individuals with diverse backgrounds and those who promote diversity and a culture of inclusion are encouraged to apply. To request reasonable accommodation contact the Affirmative Action and Equal Opportunity Department at 503-494-5148 or aaeo@ohsu.edu. \nPlease be sure to upload a Cover Letter and Resume or CV when applying online.
URL:https://ces.b2sg.org/event/research-assistant-ii-prostate-cancer-epigenetics/
LOCATION:OHSU\, 3181 SW Sam Jackson Park Rd\, Portland\, OR\, 97239\, United States
CATEGORIES:Jobs
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