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X-WR-CALNAME:Cancer Epigenetics Society
X-ORIGINAL-URL:https://ces.b2sg.org
X-WR-CALDESC:Events for Cancer Epigenetics Society
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TZID:Europe/Paris
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DTSTART:20170326T010000
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DTSTART:20171029T010000
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DTSTART;VALUE=DATE:20170502
DTEND;VALUE=DATE:20170603
DTSTAMP:20260819T012618
CREATED:20170502T180455Z
LAST-MODIFIED:20170505T115918Z
UID:17775-1493683200-1496447999@ces.b2sg.org
SUMMARY:Postdoctoral Research Fellow - Cancer Genetics and Epigenetics
DESCRIPTION:A postdoctoral position is available in the lab of David MacPherson. The position will be funded by a newly awarded R01\, with a focus on the role of key chromatin regulators in driving small cell lung cancer (SCLC)\, an aggressive neuroendocrine tumor type. Cell based screens\, genetic mouse models and study of patient derived tumors and xenografts will be employed in the research project.  The position is ideally suited to candidates interested in understanding at a molecular level how perturbation of chromatin regulators promotes SCLC and also how mutations in chromatin regulators confer vulnerabilities that can be exploited in the design of more effective therapeutics for SCLC. \n\n\n\n\n\n\nCandidates should have a PhD and/or MD\, one or more first author publications\, and experience in molecular and/or cell biology.  Expertise in chromatin biology\, genomic analyses\, mouse genetics\, and/or experience with cell based functional screens would all be looked upon favorably.  Candidates should be independent but also highly collaborative. \n\nAt Fred Hutchinson Cancer Research Center\, home to three Nobel laureates\, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent\, diagnose and treat cancer\, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy\, which harnesses the power of the immune system to treat cancer. An independent\, nonprofit research institute based in Seattle\, Fred Hutch houses the nation’s first and largest cancer prevention research program\, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network.
URL:https://ces.b2sg.org/event/postdoc-fred-hutch/
LOCATION:Fred Hutchinson Cancer Research Center\, 1100 Fairview Ave. N.\, Seattle\, WA\, 98109-1024\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/png:https://ces.b2sg.org/wp-content/uploads/2016/07/fred_hutch.png
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170503
DTEND;VALUE=DATE:20170604
DTSTAMP:20260819T012618
CREATED:20170502T185227Z
LAST-MODIFIED:20170505T115812Z
UID:17780-1493769600-1496534399@ces.b2sg.org
SUMMARY:Postdoctoral Positions - Gene Regulation\, Epigenetics and/or Cancer Biology
DESCRIPTION:Postdoctoral associate positions available for highly motivated candidates with a fresh PHD training in molecular & cell biology\, cancer biology and/or biochemistry to join the Lineberger Comprehensive Cancer Center\, the Department of Biochemistry & Biophysics\, University of North Carolina at Chapel Hill (UNC) School of Medicine\, USA. Those with a strong publication track record are also potentially eligible for a two-year postdoctoral fellowship program available from UNC Cancer Center Postdoc Trainee programs (eligibility: 1\, within less than 1-2 years since completion of PHD training; 2\, US citizen or permanent resident). \nOur laboratory emphasizes on mechanistic understandings of gene regulation\, chromatin biology\, stem cells\, and human disease\, notably cancer (see our recent publications at Molecular Cell 2013\, Blood 2015\, Cell Reports 2015; Cancer Cell 2016). Multiple on-going projects include (1) biochemical characterization of novel factors/complexes that recognize the novel chromatin modifications; (2) CRISPR/dCas9-based editing of epigenomic modifications for understanding the epigenetic pathways in gene expression; (3) knockout and knock-in mouse models with deficiency in histone methylation regulation in context of development and tumorigenesis\, with a special focus on hematopoietic cancer and disease; (4) epigenomic and transcriptome analyses (ChIP-Seq and RNA-Seq) of normal versus cancer cells to delineate pathways essential for tumor growth. \nThe salary of postdoc positions meets new federal Fair Labor Standards Act (FLSA) with a minimum salary of $47\,476 annually. Applicants should be self-motivated with a track record of publication in the above area\, have laboratory and analytical skills\, and be a critical thinker. Application shall include CV\, a cover letter (with summary of research experiences and future interests\, and expected availability date) reprints of publications\, and contact information of three references. The application materials should be sent to gregwang.unc@gmail.com. \nThe University of North Carolina at Chapel Hill is an equal opportunity and affirmative action employer.
URL:https://ces.b2sg.org/event/postdoc-epigenetics-cancer-bio/
LOCATION:University of North Carolina – UNC-Chapel Hill\, Chapel Hill\, NC\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/png:https://ces.b2sg.org/wp-content/uploads/2016/07/U_North_Carolina-2.png
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170503
DTEND;VALUE=DATE:20170604
DTSTAMP:20260819T012618
CREATED:20170503T081626Z
LAST-MODIFIED:20170505T120129Z
UID:17783-1493769600-1496534399@ces.b2sg.org
SUMMARY:Postdoctoral Researcher – Structural Biology
DESCRIPTION:The laboratory of Dr. Ernst Schonbrunn at Moffitt Cancer Center is seeking a postdoctoral researcher to work on inter-disciplinary projects towards the structural biology of proteins as drug targets. The position provides exciting opportunities for structural\, biochemical and cell-based studies of various drug-target interactions and the rational design of new inhibitors with potential as therapeutics. We work in team with medicinal chemists\, biologists and clinicians on the targeting of proteins involved in signaling and epigenetic events. \nThe successful candidate is a highly motivated individual with a PhD or equivalent degree in Biochemistry\, Chemistry or related field. Demonstrated expertise in protein crystallography and biochemical/biophysical characterization of proteins is required.  Candidates must be enthusiastic with excellent organizational skills and effective at working independently\, while also collaborating and assisting the team in its collective research goals. Attention to detail and ability to work on multiple projects is required. Excellent verbal and written communication skills are required.  \nThe Moffitt Cancer Center is a modern research facility on the University of South Florida Campus that conducts research on various aspects of Cancer Biology. The research environment includes state of the art core facilities to support basic research. Please apply online at www.moffitt.org/careers to REQ ID 21506 and send cover letter\, CV and the names and contact information of three references via email to ernst.schonbrunn@moffitt.org. \nMoffitt Cancer Center is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race\, color\, religion\, sex\, sexual orientation\, gender identity\, national origin\, age\, or protected veteran or disabled status. We seek candidates whose skills\, and personal and professional experience\, have prepared them to contribute to our commitment to diversity and excellence.  \n 
URL:https://ces.b2sg.org/event/postdoc-researcher-structural-bio/
LOCATION:Moffitt Cancer Center Magnolia Campus\, 12902 USF Magnolia Drive\, Tampa\, FL\, 33612\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/05/Moffitt-1.jpg
ORGANIZER;CN="Ernst%20Schonbrunn":MAILTO:ernst.schonbrunn@moffitt.org
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170503
DTEND;VALUE=DATE:20170604
DTSTAMP:20260819T012618
CREATED:20170503T084135Z
LAST-MODIFIED:20170505T120239Z
UID:17789-1493769600-1496534399@ces.b2sg.org
SUMMARY:Postdoctoral Fellow - Molecular Oncology
DESCRIPTION:A postdoctoral position is available in the laboratory of Dr. Florian Karreth at the Moffitt Cancer Center. The Karreth lab combines innovative mouse modeling approaches with molecular biology and biochemistry techniques to better understand the crosstalk between oncogenic signaling and non-coding RNAs in the development\, progression\, and resistance of cancer. \nWe are particularly interested in identifying and characterizing protein-coding and non-coding genes that cooperate with oncogenic MAPK signaling to promote tumor progression and drug resistance\, with an emphasis on melanoma. Moreover\, we are studying the oncogenic functions of lncRNAs in ovarian cancer. For more information visit our lab website at http://labpages2.moffitt.org/karreth. \nWe seek a talented and dedicated individual with an interest in characterizing proteins that promote the progression and drug resistance of melanoma.   \nCandidates must demonstrate excellent communication skills\, have a proven track record of scientific productivity\, and be able to work collaboratively in a team.   Experience in mouse modeling and/or oncogenic signaling is highly desirable.   We also seek a talented and dedicated individual with an interest in understanding how ovarian cancer risk SNPs affect lncRNAs expression and function. \nSuccessful candidates will work independently and collaboratively\, design and execute experiments\, and analyze and interpret data. He/She will present his/her findings to the lab during weekly lab meetings\, to the Moffitt community at research-in-progress meetings\, and to the international community at conferences. He/She will author grants and manuscripts\, and mentor students. \nPh.D. or M.D.\, preferably not received more than two years ago. \nThe outstanding research environment includes a new dedicated research building\, state-of-the-art core facilities (e.g. Molecular Genomics\, Flow Cytometry\, Proteomics\, Microscopy\, Transgenic)\, a modern vivarium\, and access to clinical material. A competitive salary and benefits package will be offered to the successful candidate. Interested applicants should email a letter describing their interest and previous experience as well as a CV including the names and contact information of three references to florian.karreth@moffitt.org. \nThe H. Lee Moffitt Cancer and Research Institute is a modern facility in Tampa\, Florida.  We strive to be the leader in understanding in the complexity of cancer through team science and applying those insights for human benefits.  Be part of the cure by joining Moffitt’s team of 800 research faculty scientists\, career staff scientists\, postdocs\, graduate students and support staff dedicated to cancer research. \n 
URL:https://ces.b2sg.org/event/postdoc-molecular-oncology/
LOCATION:Moffitt Cancer Center Magnolia Campus\, 12902 USF Magnolia Drive\, Tampa\, FL\, 33612\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/05/Moffitt-1.jpg
ORGANIZER;CN="Florian%20Karreth":MAILTO: florian.karreth@moffitt.org.
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170504
DTEND;VALUE=DATE:20170605
DTSTAMP:20260819T012618
CREATED:20170504T084233Z
LAST-MODIFIED:20170505T115446Z
UID:17817-1493856000-1496620799@ces.b2sg.org
SUMMARY:Research Associate - Epigenetics
DESCRIPTION:To enable Guardant Health to lead the disruption of cancer treatments through non-invasive cancer screening\, the Technology Development Team is seeking a highly motivated Research Associate to help develop\, test\, and improve sample preparation technologies for rare variant and epigenetic studies with next-generation sequencing. At Guardant\, we leverage the most advanced technologies and work with leaders in many different fields to create the most impactful and meaningful technologies for cancer management. \nAs a Research Associate supporting product and technology development\, you will work with members within the team and interface with multiple teams including process engineering\, clinical operations\, research operations\, and bioinformatics. You will be hands on in the lab and be required to design\, implement\, and validate new technologies related to liquid biopsy sequencing assays for the early detection\, treatment\, and monitoring of all cancer types. \nRESPONSIBILITIES \n\nOperate next generation sequencing instruments\nRun sequencing sample preparation assays in medium to high throughput environment\nTest and improve new sequencing sample preparation assays\nLog and track research samples throughout sequencing workflow\nMaintain appropriate inventory of lab supplies\nBring a can do attitude to solve new and challenging problems in a high pace environment\nAnalyze data and troubleshoot issues within the tech dev team and among other teams\nCollaborate with all functions within project teams\nEngage in early design of products and perform experiments both independently and under the supervision of Senior team members within Tech Dev and Bioinformatics groups\nBe able to present updates\, write reports and SOPs\, and contribute to technical discussions\n\nABOUT YOU \n\nThe ability to handle biological samples (i.e. tissue\, biofluid\, etc.) is a must\nExcellent written and oral communication skills is a must\nProfessional hands-on experience in industrial setting in genomics field is a plus (operational experience is preferred)\nHands-on experience in running sequencing platforms and assays is a plus\n\nGuardant Health develops breakthrough diagnostic technologies to improve cancer management. With Guardant360\, we offer real-time\, biopsy-free tumor sequencing that tracks tumor genomics in real-time and identifies associated treatment options. The recent introduction of groundbreaking analytical tools\, including our Tumor Response Map and a mobile-enabled physician portal\, further advance Guardant Health’s momentum. \nGuardant Health has raised almost $200M from OrbiMed\, Sequoia Capital\, Khosla Ventures\, Lightspeed Venture Partners\, and Formation8\, and is led by a seasoned management team of thought leaders and successful serial entrepreneurs in next generation sequencing and rare cell diagnostics. They are advised by an oncologist-led medical steering committee from leading cancer centers.
URL:https://ces.b2sg.org/event/research-associate-epigenetics-gh/
LOCATION:Guardant Health\, 505 Penobscot Dr.\, Redwood City\, CA\, 94063\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/05/guardant-health.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170504
DTEND;VALUE=DATE:20170605
DTSTAMP:20260819T012618
CREATED:20170504T170124Z
LAST-MODIFIED:20170505T115403Z
UID:17822-1493856000-1496620799@ces.b2sg.org
SUMMARY:Postdoc Position - Investigator\, Medicinal Chemistry
DESCRIPTION:Basic qualifications: \n • PhD degree in Organic Chemistry\, or Medicinal Chemistry.\n• 0 to 3 years of professional and/or industrial experience.\n• High level of synthetic chemistry expertise allowing one to plan synthetic routes to\, and prepare molecules of interest to advance lead optimization efforts.\n• Well versed in the application of new synthetic methodology.\n• High level of scientific credibility as demonstrated through peer-reviewed publications\, presentations\, or patents. \nPreferred qualifications: \n • Post-doc\n• Demonstrated autonomy in decision making.\n• Ability to excel in a team environment and work efficiently in an open-plan laboratory.\n• Excellent written and oral communication skills. \nDetails: \n The successful applicant will join a highly motivated medicinal chemistry team within Oncology Research & Development where the focus will be on progressing hit series through to candidate selection against Epigenetic targets.  The successful applicant will have opportunities to design and implement insightful and creative medicinal chemistry strategies to fulfill these objectives. The applicant will be expected to develop a deep expertise in lead optimization tactics including state-of-the-art synthesis\, purification\, and computational tools. \nPlease note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license\, GSK may be required to capture and report expenses GSK incurs\, on your behalf\, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information\, please visit GSK’s Transparency Reporting For the Record site.
URL:https://ces.b2sg.org/event/postdoc-med-chem-gsk/
LOCATION:gsk\, 1250 S Collegeville Rd\, Collegeville\, PA\, 19426\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/05/GSK.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170504
DTEND;VALUE=DATE:20170605
DTSTAMP:20260819T012618
CREATED:20170504T172327Z
LAST-MODIFIED:20170504T172701Z
UID:17825-1493856000-1496620799@ces.b2sg.org
SUMMARY:Senior Scientific Researcher - Molecular Biology
DESCRIPTION:The Position\nWe are seeking a Senior Scientific Researcher in the Department of Molecular Biology to assist with the development of an advanced cell-based molecular genetics platform. She/he will utilize and create diverse nucleic-acid-based technologies for targeted manipulation of primary and immortalized cells\, with the ultimate goal of improving upon in vitro disease models and approaches for scalable functional genomic screening. The candidate will be expected to work creatively and independently within a dynamic\, highly collaborative research environment. \nWho You Are\nA self-motivated candidate with a PhD in Genetics\, Molecular Biology\, Biochemistry\, Cancer Biology\, or a related discipline. Qualified candidates will have a skillset demonstrating successful application of gene expression analyses and genetic manipulation either in cell-based systems or model organisms. Preferred expertise includes some or all of the following: molecular cloning\, RNA/DNA/protein quantification\, 2D and 3D cell culture\, primary and/or stem cell models\, genome engineering\, epigenetics\, and viral vector development/use. Working knowledge of pooled vector-based screening\, Next-Gen Sequencing (NGS)\, biostatistics\, and/or basic bioinformatics is strongly desired. The successful candidate will be highly organized\, and have excellent communication skills\, both written and verbal. \nWho We Are\nA member of the Roche Group\, Genentech has been at the forefront of the biotechnology industry for more than 40 years\, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work. \nThe next step is yours. To apply today\, click on the “Apply online” button. \nGenentech is an equal opportunity employer & prohibits unlawful discrimination based on race\, color\, religion\, gender\, sexual orientation\, gender identity/expression\, national origin/ancestry\, age\, disability\, marital & veteran status. For more information about equal employment opportunity\, visit our Genentech Careers page.
URL:https://ces.b2sg.org/event/sen-researcher-mol-bio-genentech/
LOCATION:Genentech\, 1 DNA Way\, South San Francisco\, CA\, 94080\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/05/genentech-logo.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170505
DTEND;VALUE=DATE:20170606
DTSTAMP:20260819T012618
CREATED:20170505T073927Z
LAST-MODIFIED:20170505T115245Z
UID:17828-1493942400-1496707199@ces.b2sg.org
SUMMARY:Research Associate II – Leukemia Lab
DESCRIPTION:A Research Associate II position is available in the Leukemia Research Laboratory of Gehr Family Center for Leukemia Research and the Beckman Research Institute of City of Hope. \nThe Center is supported by outstanding core facilities including\, but not limited to\, a large human and mouse leukemia tissue bank\, and GMP facilities for new drug development and exceptional Sequencing and Bioinformatics services. Our long-term goal is to elucidate the mechanisms of leukemogenesis and drug resistance of primitive leukemia cells\, and to identify novel therapeutic approaches in blood cancers. Our current research efforts are directed towards understanding the molecular and cellular pathways underlying the pathogenesis of acute myeloid leukemia (AML) using a combination of genetics\, genomics\, biochemistry\, proteomics\, molecular biology and cellular biology approaches. Our experimental systems include both genetic mouse models and primary leukemia stem cells from AML patients. The focus of this position is to understand the role of epigenetic changes in leukemia development\, progression and maintenance. \nPlease include a cover letter stating research interests and experiences\, curriculum vitae\, and names and contact information of three references. \nMinimum Education and Skills Required for Consideration: \n\nBachelor’s degree in biomedical related fields plus two years related research/laboratory experience.\nMaster’s degree in biomedical related fields preferred plus one year related research/laboratory experience preferred.\nMust be highly motivated with excellent organization and communication skills.\nCandidates with skills in molecular biology\, biochemistry\, tissue culture\, flow cytometry\, gene transfer\, mouse handling and transplantation techniques are preferred.\n\nAbout City of Hope \nCity of Hope\, an innovative biomedical research\, treatment and educational institution with over 4000 employees\, is dedicated to the prevention and cure of cancer and other life-threatening diseases and guided by a compassionate\, patient-centered philosophy. Founded in 1913 and headquartered in Duarte\, California\, City of Hope is a remarkable non-profit institution\, where compassion and advanced care go hand-in-hand with excellence in clinical and scientific research. City of Hope is a National Cancer Institute designated Comprehensive Cancer Center and a founding member of the National Comprehensive Cancer Network\, an alliance of the nation’s 20 leading cancer centers that develops and institutes standards of care for cancer treatment. \nCity of Hope is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race\, religion\, color\, national origin\, sex\, sexual orientation\, gender identity\, age\, status as a protected veteran\, or status as a qualified individual with disability.
URL:https://ces.b2sg.org/event/research-associate-ii-leukemia-lab/
LOCATION:Beckman Research Institute\, 1500 E Duarte Rd.\, Duarte\, CA\, 91741\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/png:https://ces.b2sg.org/wp-content/uploads/2017/02/City-of-hope.png
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170505
DTEND;VALUE=DATE:20170606
DTSTAMP:20260819T012618
CREATED:20170505T112515Z
LAST-MODIFIED:20170511T063443Z
UID:17829-1493942400-1496707199@ces.b2sg.org
SUMMARY:Postdoctoral Fellow- Oncology
DESCRIPTION:We seek a driven and accomplished postdoctoral fellow to join the cancer epigenetics group within the Oncology R&D (ORD) unit of Pfizer’s Worldwide R&D (WRD) division in La Jolla\, California. The successful candidate will collaborate with our cancer-immunopharmacology group to study the roles of epigenetic enzymes in anti-tumor immune responses. Guided by experienced mentors with strong academic track records\, the successful candidate will study fundamental questions in cancer immunology with the ultimate goal of publication in major scientific journals. Thus\, a strong scientific background with relevant expertise and documented accomplishments including significant publications is required. In addition\, the successful candidate will have a strong interest in translating results into novel immunotherapies for cancer. He/she will be highly self-motivated with a sense of urgency and focus on important problems. While driven to make strong individual contributions\, the successful candidate will also enjoy a highly interactive\, team-oriented environment and thrive by taking advantage of the significant multi-disciplinary resources available at Pfizer. This will be facilitated by the candidate’s excellent communication and interpersonal skills\, which complement strong work ethics and overall scientific excellence. \nResponsibilities \nPrimary Duties: \n\nWork independently and as part of teams to conceive\, design\, execute\, analyze/interpret\, and refine experiments ranging from biochemical and molecular assays\, in vitro and in vivo immunological functional assays in model systems\, and clinical sample analysis. Specific duties to include:\nContribute intellectually and at the bench to the conception\, design\, execution\, analysis\, interpretation and internal or external presentation of studies of epigenetic modulators of the anti-tumor immune response.\nKeep abreast with the literature and internal developments to become an expert point of contact for colleagues in the field of epigenetic immunopharmacology\nIndependently\, but with guidance by experienced mentors\, develop results into compelling stories for publication in major scientific journals and presentations on major scientific meetings and conferences\, both internally and externally\nApply genetic and pharmacologic approaches to modulate targets in vitro and in vivo to assess functional impacts on tumor cells and immune cells\, and on anti-tumor immune responses in syngeneic xenograft models and genetically engineered mutant mouse models of cancer. This will include CRISPR\, RNAi\, viral vector delivery\, transfection\, antibodies\, small molecules and other pharmacologic approaches to modulate targets.\nExecute secondary assays across various technology platforms – qRT-PCR\, immunoprecipitation\, ChIP-seq\, ATAC-seq\, FACS\, immunofluorescence\, western blotting\, ELISA\, high content screening\, etc.\nDevelop and apply complex in vitro assays for exploring target biology in tumor cells versus immune cells including T-cell functional assays\, co-culture assays\, ect.\nCollaborate with computational biology groups to analyze data including ChIP-seq\, RNA-seq\, ATAC-seq to support mechanism of action studies.\nEmploy computational and proteomic methods for tumor neoantigen prediction and functional validation\nUse electronic data capture/analysis tools such as Excel\, GraphPad\, Biobook\, Spotfire and PowerPoint for experimental documentation and data analysis/presentations.\nPresent research results and methodologies at weekly meetings with immediate supervisor and/or project leader\, and at meetings with members of the oncology research unit as appropriate.\nContribute to building a culture that embraces scientific excellence\, urgency\, partnerships with key stakeholders\, continuous learning and improvement\, increasing technical skill base and cancer biology expertise; take a proactive role in personal growth and scientific development.\n\nQualifications \nEducation and Experience: \n\nPh.D. in Cell Biology\, Molecular Biology\, or Immunology (or a comparable biological science) with a track record of scientific accomplishment as exemplified by significant scientific publications\nExperience with devising and implementing in vitro and in vivo immunological functional assays\nExperience in immuno-oncology and/or chromatin biology/epigenetics is desirable\nExperience in nucleic acid and protein extraction techniques and downstream analyses including quantitative RT-PCR\, immunoprecipitation (including ChIP)\, and immunoblotting.\nExperience with computational tools for antigen prediction\, NGS experiment design and data analyses\, including epigenomic data\, is desired\nAbility to work in a team environment; excellent written and oral communication skills in English; strong presentation skills and ability to discuss data at project team meetings.\nAble to master new concepts and techniques quickly.\nStrong attention to detail and organizational skills to manage projects in parallel\n\nPHYSICAL/MENTAL REQUIREMENTS: \nLifting\, sitting\, standing\, walking\, bending\, ability to perform mathematical calculations\, ability to read\, comprehend and process complex scientific matter\, and perform complex data analysis. Ability to travel by air\, water and ground. \nNON-STANDARD WORK SCHEDULE\, TRAVEL OR ENVIRONMENT REQUIREMENTS: \nAbility to accommodate non-standard work schedules due to experimental regimen or travel. Ability to adhere to safe work practices and wear full personal protective equipment. Ability to travel nationally and internationally. \nA career at Pfizer offers opportunity\, ownership and impact. All over the world\, Pfizer colleagues work together to positively impact health for everyone\, everywhere. Our colleagues have the opportunity to grow and develop a career that offers both individual and company success; be part of an ownership culture that values diversity and where all colleagues are energized and engaged; and the ability to impact the health and lives of millions of people. Pfizer\, a global leader in the biopharmaceutical industry\, is continuously seeking top talent who are inspired by our purpose to innovate to bring therapies to patients that significantly improve their lives. \nPfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race\, color\, religion\, sex\, sexual orientation\, age\, gender identity or gender expression\, national origin\, disability or veteran status. Pfizer also complies with all applicable national\, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.
URL:https://ces.b2sg.org/event/postdoc-oncology-pfizer/
LOCATION:Pfizer – La Jolla\, CA\, 10350 N Torrey Pines Rd\, La Jolla\, CA\, 92037\, United States
CATEGORIES:Jobs
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170506
DTEND;VALUE=DATE:20170607
DTSTAMP:20260819T012618
CREATED:20170506T044808Z
LAST-MODIFIED:20170506T072719Z
UID:17835-1494028800-1496793599@ces.b2sg.org
SUMMARY:Postdoc - epigenetic research
DESCRIPTION:A postdoctoral position is immediately available at the Vanderbilt University Genetics Institute and Department of Biochemistry. Our group is interested in the role of non-coding sequence variation in complex disease. Research in the Hodges Lab strives to understand how epigenetic features shape human genomes.  \nOur work aims to dissect the relationship between DNAmethylation and gene regulation\, particularly with respect to the gene regulatory activity of non-coding functional elements. We study this relationship on two levels; first\, we are interested in how DNA methylation states are established in differentiating cells. Second\, we are interested in the relationship between genotype and DNA methylation state (epitype). Projects in our lab address these questions utilizing innovative biochemical\, functional genomic and bioinformatic approaches. \nThe desired candidate should have a recent PhD in biochemistry\, genetics or related discipline\, with a strong molecular biology background. Experience with next-generation sequencing\, statistical genetics\, and bioinformatics is a priority. Please send CVs along with contact information for three references to emily.hodges@vanderbilt.edu.
URL:https://ces.b2sg.org/event/postdoc-gen-vanderbilt/
LOCATION:Vanderbilt University Genetics Institute and Department of Biochemistry\, 673B Light Hall\, Nashville\, TN\, 37205\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/png:https://ces.b2sg.org/wp-content/uploads/2017/05/venderbilt-u.png
ORGANIZER;CN="Emily%20Hodges":MAILTO:emily.hodges@vanderbilt.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170506
DTEND;VALUE=DATE:20170607
DTSTAMP:20260819T012618
CREATED:20170506T070545Z
LAST-MODIFIED:20170509T075251Z
UID:17839-1494028800-1496793599@ces.b2sg.org
SUMMARY:Research assistant II - prostate cancer epigenetics
DESCRIPTION:An exciting opportunity has been created for an experienced researcher to join the Alumkal Laboratory at the OHSU Knight Cancer Institute as a Research Assistant 2 in Portland\, OR. The individual will work with Dr. Joshi Alumkal\, Co-Leader of the OHSU Prostate Cancer Research Program.  Our laboratory focuses on identifying mechanisms by which key chromatin modifying enzymes and chromatin readers drive transcription of pathways that promote treatment resistance. We use genomics studies in prostate cancer clinical samples and prostate cancer cell line model systems and functional studies to understand this process. Our goal is to develop new\, targeted treatment strategies for men with advanced prostate cancer. \nThe Research Assistant 2 will be responsible for carrying out experiments in the laboratory\, helping with ordering supplies\, and participating in research to study cancer epigenetics and drug resistance in prostate cancer. Their duties will also include performing mouse xenograft tumor growth experiments with drug injections or drug gavage\, basic molecular biology techniques including cell culture\, DNA/RNA/protein extraction\, QPCR\, Western blots\, maintaining meticulous records of experimental procedures\, and preparing material for presentation and/or submission to peer reviewed publications. \nRequired Qualifications: \n\nBachelor’s degree with major courses in field of research and no experience\, Or an AA/RN and 2 years of experience\nAbility to prioritize multiple tasks at one time\nExcellent verbal and written communication skills\nExcellent analytical and organizational skills\nAbility to work independently and as part of a team while being collaborative in resolving problems\nProficient with computers running Windows software such a MS Excel\, Access\, Word and PowerPoint\nExcellent customer service skills both on the phone and in person\nEnergy and drive to coordinate multiple projects simultaneously\nAbility to use tact and diplomacy to maintain effective working relationships\nWorking knowledge of basic molecular biology techniques: PCR\, DNA/RNA extraction\nProficiency with mammalian cell culture\nAble to perform the essential functions of the position with or without accommodation\n\nPreferred Qualifications: \n\n2 years of experience in a molecular biology setting\nExpertise with recombinant DNA techniques\, Western blots\, and RNAi/plasmid transfections\nRodent handling experience\, especially with xenograft tumor growth experiments involving injection and/or gavage treatment\n\nWork schedule\, hours\, salary range and FTE: \n\nFTE: 1.0 FTE\, Full Time\nSchedule: Monday – Friday\, with occasional night and weekend hours\nSalary Range: $30\,638 – $40\,000\nLocation: Portland\, OR (South Waterfront)\nJob Type: Research\n\nOregon Health & Science University values a diverse and culturally competent workforce. We are proud of our commitment to being an equal opportunity\, affirmative action organization that does not discriminate against applicants on the basis of any protected class status\, including disability status and protected veteran status. Individuals with diverse backgrounds and those who promote diversity and a culture of inclusion are encouraged to apply. To request reasonable accommodation contact the Affirmative Action and Equal Opportunity Department at 503-494-5148 or aaeo@ohsu.edu. \nPlease be sure to upload a Cover Letter and Resume or CV when applying online.
URL:https://ces.b2sg.org/event/research-assistant-ii-prostate-cancer-epigenetics/
LOCATION:OHSU\, 3181 SW Sam Jackson Park Rd\, Portland\, OR\, 97239\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170509
DTEND;VALUE=DATE:20170610
DTSTAMP:20260819T012618
CREATED:20170509T043559Z
LAST-MODIFIED:20170509T044746Z
UID:17916-1494288000-1497052799@ces.b2sg.org
SUMMARY:Postdoctoral Associate - cancer epigenetics
DESCRIPTION:A Postdoctoral Associate position is available in the Dan L Duncan Comprehensive Cancer Center to perform bioinformatics data analysis to understand epigenetic gene regulation and transcription dynamics in various biological processes and disease models including cancer. bioinformatics can address such problems at the systems level. Develop and test novel bioinformatics algorithms in many areas spanning epigenomics and transcriptomics – in the context of stem cells\, cancer and aging. \nIdeal candiates should have a PhD in a quantitative field\, strong programming skills (Python/Perl\, R\, C/C++) and/or large-scale data analysis skills. Substantial experience in Bioinformatics/Computational Biology is a plus. A non-bioinformatics background with strong training in other areas (e.g.\, physics or computer science) will also be considered.
URL:https://ces.b2sg.org/event/postdoc-bcm-may2017/
LOCATION:Baylor College of Medicine\, 1 Baylor Plaza\, Houston\, TX\, 77030\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170509
DTEND;VALUE=DATE:20170610
DTSTAMP:20260819T012618
CREATED:20170509T050512Z
LAST-MODIFIED:20170509T051255Z
UID:17921-1494288000-1497052799@ces.b2sg.org
SUMMARY:Research Specialist A - Cancer Epigenetics
DESCRIPTION:The candidate will work in the High-Throughput Screening Core (HTSC) in the Perelman School of Medicine (PSOM). He/she will work with the Scientific and Technical Directors of the core to further design\, to optimize and validate biological assays in high-density formats (i.e. 384 well microtiter plates) for primary human cancers that can be screened against libraries of FDA approved drugs\, as part of a collaborative research initiative between the Chemogenomic Discovery Program\, Precision Medicine\, and Hospital of University of Pennsylvania. The candidate will also dedicate effort to high-throughput cell based screens designed to dissect the role of epigenetics in cellular senescence.  \nSpecific responsibilities will include moderately complex procedures/techniques in eukaryotic/mammalian cell-culture\, molecular biology\, cell biology\, and high-throughput genetic/chemical screening. The candidate will operate and maintain automated laboratory robotic workstations related to high-throughput screening; prepare and manage libraries of siRNA\, shRNA\, cDNA\, CRISPR and drug-like small molecule libraries for high-throughput screening; and analyze\, interpret\, and prepare reports of large data sets. Additional responsibilities will include literature searches\, maintaining articulate documentation of daily tasks and maintenance of the laboratory’s databases/logs and inventory (i.e. supplies\, reagents\, and equipment). \nA Bachelor’s Degree and 0 to 1 year of experience or equivalent combination of education and experience is required. 1 to 3 years of experience preferred.  The ideal candidate will have strong organizational skills\, effective communication skills; and the ability to problem-solve and work independently. The applicant should have basic understanding of cell biology\, molecular biology and biochemistry. Experience in bioinformatics and programming is desirable. \nThe University of Pennsylvania\, the largest private employer in Philadelphia\, is a world-renowned leader in education\, research\, and innovation. This historic\, Ivy League school consistently ranks among the top 10 universities in the annual U.S. News & World Report survey. Penn has 12 highly-regarded schools that provide opportunities for undergraduate\, graduate and continuing education\, all influenced by Penn’s distinctive interdisciplinary approach to scholarship and learning. \nPenn offers a unique working environment within the city of Philadelphia. The University is situated on a beautiful urban campus\, with easy access to a range of educational\, cultural\, and recreational activities. With its historical significance and landmarks\, lively cultural offerings\, and wide variety of atmospheres\, Philadelphia is the perfect place to call home for work and play. \nThe University offers a competitive benefits package that includes excellent healthcare and tuition benefits for employees and their families\, generous retirement benefits\, a wide variety of professional development opportunities\, supportive work and family benefits\, a wealth of health and wellness programs and resources\, and much more.
URL:https://ces.b2sg.org/event/research-specialist-penn-may2017/
LOCATION:University of Pennsylvania\, 3400 Civic Center Blvd\, Philadelphia\, 19104\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170510
DTEND;VALUE=DATE:20170611
DTSTAMP:20260819T012618
CREATED:20170510T095035Z
LAST-MODIFIED:20170510T101423Z
UID:17945-1494374400-1497139199@ces.b2sg.org
SUMMARY:Postdoctoral Associate - Stem Cell Biology and Cancer Epigenetics
DESCRIPTION:An academic postdoctoral associate position is available in the laboratory of Dr. Jennifer Trowbridge to study epigenetic mechanisms governing hematopoietic stem cell lineage commitment\, and how deregulation of epigenetic modifications leads to myeloproliferative disorders including leukemia (http://trowbridgelab.com). \nThe Jackson Laboratory (JAX) offers a unique research and training environment characterized by multidisciplinary scientific collaboration\, unparalleled mouse resources\, outstanding core services\, and is located adjacent to Acadia National Park in coastal Maine. Translational research collaborations in genomics-based\, personalized medicine are fostered through our new JAX Genomic Medicine campus in Farmington\, CT. In addition to lab-based training\, JAX has developed a unique program for trainees to expand their professional skills in science communication\, entrepreneurship\, teaching\, mentoring and laboratory management to best prepare postdocs for future career opportunities. \nRequired Skills \nAbility to plan\, execute and analyze an independent research project as well as exceptional verbal and written communication skills. Preference given to self-motivated and career oriented individuals. \nRequired Experience \nA Ph.D. in biological or related sciences is required\, and a strong training background in molecular biology\, cell biology and/or epigenetics is preferred. \nApply by submitting a cover letter describing past research accomplishments\, research interests and career aspirations\, a current CV\, and the names of three references\, as one PDF file.
URL:https://ces.b2sg.org/event/postdoc-jackson-lab-10may2017/
LOCATION:Jackson Laboratory\, 600 Main Street\, Bar Harbor\, ME\, 04609\, United States
CATEGORIES:Jobs
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170510
DTEND;VALUE=DATE:20170611
DTSTAMP:20260819T012618
CREATED:20170510T110603Z
LAST-MODIFIED:20170510T112119Z
UID:17948-1494374400-1497139199@ces.b2sg.org
SUMMARY:Research Associate I - Cancer Epigenetics
DESCRIPTION:Duties:  \n\nOpening for a temporary Scientific Researcher in the Discovery Oncology Department\, to discover and validate new targets in cancer biology.\nShe/he will utilize and/or develop state of the art genetic\, epigenetic and proteomic technologies to characterize exciting oncology drug targets in the epigenetics space.\nThe successful candidate will be expected to work creatively\, independently and collaboratively.\n\nSkills:  \n\nAn ideal candidate should have a strong background in Cancer Biology and will possess the proven ability to work independently.\nHe/she should have technical skills in molecular and cellular biology.\nIn particular\, FACS\, western blotting\, cloning\, genetic manipulation of cell lines and cell culture\, cell imaging and growth analysis.\nExperience with techniques related to the study of chromatin\, epigenetics and Next Generation Sequencing is also an advantage.\nStrong organizational skills and the ability to work independently in a team environment are required.\nExcellent communication skills\, both written and verbal are essential.\n\nEducation:  \n\nA Bachelors or Masters degree with 3+ years of cancer research experience.
URL:https://ces.b2sg.org/event/research-associate-apex/
LOCATION:Apex Life Sciences\, South San Francisco \, CA\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170511
DTEND;VALUE=DATE:20170612
DTSTAMP:20260819T012618
CREATED:20170511T062816Z
LAST-MODIFIED:20170511T063321Z
UID:17952-1494460800-1497225599@ces.b2sg.org
SUMMARY:Senior Scientist - Oncology Target Discovery
DESCRIPTION:We are seeking a highly motivated scientist to join the Oncology Therapeutic Discovery Group in Pfizer’s Oncology Research Unit. The successful applicant will assist in the identification and validation of novel small molecule drug targets in the areas of cancer epigenetics\, signal transduction\, metabolism\, and immuno-oncology.  \nThe successful candidate will work independently as part of a research team that is focused on identifying and validating novel drug targets and drug combinations in the fields of cancer biology and immuno-oncology. He/She will take a proactive role in their personal growth and scientific development.  \nThe candidate is expected to \n– utilize expertise in cancer biology and molecular/cellular immunology to design\, execute\, and analyze/interpret experiments and functional genomic screens to uncover novel areas of cancer biology and /or genes that can be exploited therapeutically.\n– Present research results and methodologies at weekly/monthly group meetings and at meetings with members of the Oncology Research Unit.\n– Contribute to building a culture that embraces scientific excellence\, urgency\, partnerships with key stakeholders\, and continuous learning and improvement.  \nSpecific technical duties include:  \n– Applying genetic and pharmacologic approaches to modulate targets in vitro and assessing the functional impact on cancer initiation and progression. These include RNAi\, CRISPR\, small molecules\, antibodies and other pharmacologic approaches to modulate targets in vitro.\n– Implementing genetic and pharmacological screens to identify new targets and potential drug combinations.\n– Utilizing expertise in cancer biology to design\, execute\, and analyze/interpret experiments to advance mechanism-of-action target biology and develop innovative approaches for targeting in cancer.\n– Utilizing 2D or 3D (spheroid models\, co-culture systems\, etc) assays to measure cell proliferation\, cytokine\, or phenotypic readouts\n– Executing high content functional assays using Cellomics or Opera Confocal Fluorescent based assays.\n– Executing molecular and cell-based assays across various technology platforms to assess target modulation and measure downstream signaling pathways- qPCR\, ChIP-seq\, FACS\, immunofluorescence\, western blotting\, ELISA\, high content screening\, etc.\n– Collaborating with in vivo pharmacologists to perform in vivo efficacy and biomarker studies.\n– Utilizing electronic data capture/analysis tools such as Excel\, GraphPad\, Biobook\, Spotfire and PowerPoint for experimental documentation and data analysis/presentations. \nQualifications  \n– Education and Experience: PhD or MD PhD in Molecular Biology\, Cell Biology\, Epigenetics or Immunology (or a comparable biological science) with a minimum of 2-5 years of post-doctoral experience.\n– At least 5 years of experience working in the field of cancer biology or immunology\n– At least 2-5 years of experience in the postdoctoral/industry setting focused on target identification and validation\n– Extensive experience with genetic and/or pharmacological screens (in vitro or in vivo) – Hands on\, extensive experience working with human or murine CAR T\, CD8/CD4 or other immuno-specific cell lines\n– Ability to work in a team environment Technical Skills: – Strong track record in target identification/ validation and screening approaches using small-molecule inhibitors and/or genetic manipulation (shRNA\, CRISPR\, etc) is required\n– Strong biological and technical knowledge related to immune cell biology\, mechanism of action target validation assays\, T cell signaling and regulation is required\n– Expertise in immune and mammalian cell culture techniques required\n– Preference for candidates with also expertise in phenotypic analysis of immuno-oncology targets and pathways\n– Strong experience working as part of a cross-functional team\n– Excellent verbal/written communication and interpersonal skills Physical/Mental Requirements: Extended periods of sitting and standing
URL:https://ces.b2sg.org/event/senior-scientist-pfizer-may2017/
LOCATION:Pfizer – Pearl River\, NY\, 401 North Middletown Road\, Pearl River\, NY\, 10965\, United States
CATEGORIES:Jobs
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170511
DTEND;VALUE=DATE:20170612
DTSTAMP:20260819T012618
CREATED:20170511T071344Z
LAST-MODIFIED:20170511T072355Z
UID:17959-1494460800-1497225599@ces.b2sg.org
SUMMARY:Associate Director / Senior Scientist - Cancer Immunotherapy
DESCRIPTION:Fate’s Cancer Immunotherapy group is seeking a talented and highly motivated scientist with expertise in oncology and stroma immunobiology to join a multidisciplinary team dedicated to the discovery of novel cellular therapeutics for the treatment of cancer.  The successful candidate will play a leading role in the research and translation of new biologic modalities for off-the-shelf cancer immunotherapy.  Specifically\, the candidate will be tasked to drive ongoing efforts to identify novel strategies to improve effector persistence across tumor microenvironment and histocompatibility barrier.  The candidate must have in depth knowledge of NK cell and T cell immunology\, cancer biology\, effector cell dysfunction and exhaustion\, immunosuppression\, metabolism and trafficking. The position will require independent research as well as coordination with the greater cancer immunotherapy and cellular engineering groups. This is a full-time position reporting to the Vice President of Cancer Immunotherapy and is located at our corporate headquarters in San Diego\, CA. \nResponsibilities\n •   Identification and implementation of novel genetic and epigenetic programming and engineering strategies to improve safety and efficacy of universal cancer immunotherapy products\n •   Present research initiatives to management team and drive execution of sanctioned programs\n •   Execute research timelines to meet program and corporate objectives\n •   Scientific team management \nRequirements\n•   PhD in cell biology\, immunology or related field\n•   Minimally 4-5 years post-doctoral training with additional 3-5 years continuing experience in academia or industry\n•   Extensive experience in analyzing the interaction of hematopoietic cells\, tumor cells and microenvironment using both in vitro and in vivo functional models\n•   Expert in flow cytometry\, imaging based approaches\, cellular cytotoxicity assays and metabolism assessment to determine the biological mechanisms and activities of programmed cells\n•   Demonstration of ability to work both independently and dependently within a goal-oriented team environment\n•   Strong scientific track-record demonstrating experience and expertise in cancer immunotherapy or related fields \nWorking Conditions and Physical Requirements\n •   Will require working with blood and cell lines of human origin\n •   Will require working with rodent models\n •   100% on-site work at corporate headquarters in San Diego\, CA\n •   Evening and weekend work as necessary \nThe preceding job description indicates the general nature and level of work performed by employees within this classification. Additional and incidental duties related to the primary duties may be required from time to time. \nFor consideration send cover letter and resume to:  careers@fatetherapeutics.com and reference job code 164BV.
URL:https://ces.b2sg.org/event/fate-therapeutic-may2017/
LOCATION:Fate Therapeutics\, 3535 General Atomics Ct #200\, San Diego\, CA\, 92121\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/05/Fate-Therapeutics-1.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170511
DTEND;VALUE=DATE:20170612
DTSTAMP:20260819T012618
CREATED:20170511T115141Z
LAST-MODIFIED:20170511T172300Z
UID:17968-1494460800-1497225599@ces.b2sg.org
SUMMARY:Postdoctoral Scientist - Cancer Epigenetics
DESCRIPTION:A position is available for a Postdoctoral Scientist in the laboratory of Dr. Katherine Chiappinelli\, Ph. D. at the George Washington Cancer Center (https://smhs.gwu.edu/cancercenter/) in the Department of Microbiology\, Immunology\, & Tropical Medicine (https://smhs.gwu.edu/microbiology/) at George Washington University. Dr. Chiappinelli’s laboratory focuses on the epigenetic control of gene expression in cancer\, specifically of immune signaling in and from tumor cells. Our goal is to use epigenetic therapies to harness the power of the immune system to fight cancer. This position will assist in design\, evaluation\, and conducting experiments and research while receiving advanced training from the Principal Investigator to enhance professional skills and research independence. \nResponsibilities include: \n •Designs\, evaluates and conducts experiments.\n •Assists in the development of new ideas that promote current research.\n •Prepares and publishes scientific manuscripts.\n •Works closely with students and supervises research staff as necessary.\n •Operates specific equipment and train other laboratory personnel.\n •Performs other work related duties as assigned. The omission of specific duties does not preclude the supervisor from assigning duties that are logically related to the position. \nMinimum Qualifications: \nRequires a PhD in the field or in a related area. \nPreferred Qualifications:  \n•Impeccable aseptic technique and strong molecular biology skills (basic tissue culture\, PCR\, molecular cloning\, RNA extraction and analysis). \n •Experience in one or more of the following areas: biochemistry (protein purification and analysis\, in vitro assays\, etc.)\, genetics (genetic manipulation through CRISPR knockout\, shRNA knockdown\, etc.)\, gene expression and bioinformatics (analysis of local and global gene expression data)\, and cell biology (fluorescence microscopy\, flow-cytometry\, etc)\n •Experience working with laboratory animals is preferred. \n •Ability to prepare research for publication and present at scientific meetings. \n •Excellent organizational and communication skills.
URL:https://ces.b2sg.org/event/postdoc-scientist-gwu-may2017/
LOCATION:George Washington University\, 2121 I St NW\, Washington\, DC\, 20052\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/05/gwu-1.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170512
DTEND;VALUE=DATE:20170613
DTSTAMP:20260819T012618
CREATED:20170512T090556Z
LAST-MODIFIED:20170513T074332Z
UID:17973-1494547200-1497311999@ces.b2sg.org
SUMMARY:Postdoctoral Associate
DESCRIPTION:A position of Post-Doctoral Associate is opened in University of Pittsburgh School of Medicine to seek a motivated person to study the genomics of human cancers and to develop cancer treatment using genome targeting strategy. Two years of experience in molecular biology and cell biology are required. Candidates must possess a Ph.D. or M.D./Ph.D degree. Interested candidate should submit their inquiry and CV to Dr. Jianhua Luo\, M.D.\, Ph.D. at luoj@upmc.edu. Salary will be commensurate with experience.
URL:https://ces.b2sg.org/event/postdoctoral-associate/
LOCATION:University of Pittsburgh School of Medicine\, 3550 Terrace St\, Pittsburgh\, PA\, 15213\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170513
DTEND;VALUE=DATE:20170614
DTSTAMP:20260819T012618
CREATED:20170513T072628Z
LAST-MODIFIED:20170513T072728Z
UID:17981-1494633600-1497398399@ces.b2sg.org
SUMMARY:Research Scientist
DESCRIPTION:Dr. Kapil N. Bhalla is currently seeking a Research Scientist who will be responsible for conducting research in his NIH-funded laboratory. The focus of the basic and translational research in this laboratory includes the biology and developmental therapeutics related to epigenetic mechanisms involving histone deacetylases\, methyltransferases and demethylases\, BET proteins\, as well as the chaperone biology of heat shock proteins and their cancer relevant client proteins regulating cell growth\, differentiation and survival of the human leukemia stem/progenitor cells. \nThe preferred candidate will possess a Ph.D. in Biology\, Biological Sciences\, Life Sciences or related field; a keen interest and experience in cancer research and excellent English skills (both written and verbal).  The preferred candidate will have completed at least a 3 year Post-doctoral fellowship in an area relevant to the focus of research in Dr. Bhalla’s laboratory. In addition\, have the ability to troubleshoot in the design and conduct the laboratory studies. Experience in molecular studies involving gene transfection\, analysis of gene expression through QPCR\, microarrays\, immunoblots and flow cytometry\, as well as experience in chromatin immunoprecipitation studies\, evaluation of protein biochemistry with 2D gels and the yeast-two-hybrid system\, and tissue culture techniques is required. Experience in the ability to utilize CRISPR technology for gene editing and to utilize confocal microscopy for molecular imaging is highly desired. Experience in xenograft and genetically-engineered animal models of cancer and/or leukemia\, and confocal microscopy is also desired.  An outstanding research environment\, new laboratory and core facilities are provided. \nKEY FUNCTIONS \n1. The basic and translational research focus of this laboratory includes epigenetic mechanisms involving histone deacetylases\, methyltransferases and demethylases\, heat shock proteins and their cancer and leukemia-relevant client proteins\, as well as transfection and functional analyses of genes regulating cell death/survival of human cancer cells. Experience in animal studies involving NOD/SCID or nude mice\, and mouse imaging (xenogen and MRI) is highly desirable. Experience in molecular techniques involving plasmid DNA preparations and transfection\, the analysis of gene expression including QPCR\, microarrays\, chromatin immunoprecipitation\, evaluation of protein biochemistry with 2D gels\, animal models\, the yeast-two-hybrid system\, confocal microscopy and tissue culture are also preferred. \n2. Plans\, organizes\, coordinates\, directs\, and participates in scientific research projects.  \nPerforms quality research in relation to current research projects\, and other identified needs. Interprets results of experiments\, and makes necessary changes in procedures when needed.  Compiles data sheets. \n3. Organizes and performs routine procedures involving molecular biology and biochemistry of RNA processing. Requires experience in tissue culture\, DNA & RNA preparation\, PCR\, DNA cloning\, protein synthesis and electrophoresis.    Responsible for providing laboratory services\, tissue culture\, processing research samples\, and/or cataloging samples as required. Interacts with the principal investigators\, postdoctoral fellows and other research personnel in communicating experimental design and results. \n4. Requires knowledge of standard radiographic techniques. Dark room usage is essential as is use and proper handling of radioisotopes. \nMust be able to comply with all institutional safety policies including Universal Precautions and OSHA standards when handling toxic\, hazardous\, flammable\, or potentially infectious or carcinogenic materials.  This may require wearing common protective garments or equipment such as gloves\, eye protection\, face mask\, gown or lab coat\, etc.  Additionally some procedures may require the use of a fume hood or biological safety cabinet. \n5. Work with laboratory animals such as mice and rats and to perform interventional procedures such as tail vein injections and orthotopic implantations. Retrieves\, maintains\, and catalogs specimen stocks from outside reference laboratories.  Assists in other laboratory activities as needed. \n6. Performs and coordinates scientific experiments in a collaborative effort with other technicians\, postdoctoral fellows\, and staff members.  Monitors work flow as it pertains to the need for supplies\, equipment maintenance and stock solutions.  Performs preventive maintenance on laboratory equipment. \n7. Equipment monitoring on a daily basis verifying correct temperatures of freezers\, refrigerators\, incubators\, etc.  Equipment maintenance on a weekly basis includes cleaning and disinfecting refrigerators and incubators.  Daily counter clean up and disinfection to ensure safety of the laboratory work place.  Bags waste and transports to appropriate refuse area utilizing safety standards and guidelines.  Maintains all safety precautions. \n8. Assigns and reviews work of subordinates\, determines specific goals or objectives to be attained\, evaluates resulting research data\, and revises techniques or approaches to work problems. Supervises the design\, development\, or adapting of equipment used in experiments or research to obtain desired results. Utilizes institutional and departmental databases to perform data retrieval for analysis.  Designs retrieval templates for standard queries.  Apply bio-statistical methods in analyzing clinical data such as pretreatment characteristics\, response to treatment\, toxicities\, and mortality\, etc.  \nConducts Library Work.  Finds and copies journal articles as required.  Reads and understands articles related to ongoing research.  Maintains references in a manual filing system.  Requires good reading and comprehension skills as well as diligence\, patience and ability to carry several heavy books at a time. \n9. Assemble samples\, reagents\, dry or wet ice\, data and packaging materials; draft a cover letter\, accurately and legibly fill out shipping labels; carry package to receiving area on ground floor prior to pick up.  Keep accurate legible logs of outgoing and incoming packages.  For incoming packages\, ascertain contents\, store at appropriate location\, file information sheets and notify principal investigator.  Update pertinent inventory logs. \n10. Compiles\, writes\, and submits reports to superior.  Plans and supervises the training of technicians and other laboratory personnel with respect to proper laboratory techniques\, the use of laboratory equipment\, and safety procedures. \n11. Presents findings of data to PI and prepares scientific documents for publication.  Presents findings of research projects to professional groups and prepares scientific documents for publication.  \n12. Performs related work as required. \nsource:sonj \n\nEDUCATON \nRequired: PhD in one of the natural sciences or related field or Medical degree \n  \nEXPERIENCE \nRequired: With PhD\, no experience required. With Medical degree\, two years of experience in experimental or scientific work. \nPreferred: Completion of a 3 year post-doctoral fellowship.
URL:https://ces.b2sg.org/event/researcher2-mdanderson-may2017/
LOCATION:MD Anderson Cancer Center\, 1515 Holcombe Blvd\, Houston\, TX\, 77030\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170523
DTEND;VALUE=DATE:20170624
DTSTAMP:20260819T012618
CREATED:20170523T125818Z
LAST-MODIFIED:20170617T065128Z
UID:18207-1495497600-1498262399@ces.b2sg.org
SUMMARY:Bioinformatics Research Scientist
DESCRIPTION:A Bioinformatics Research Scientist position is available in the lab of Dr. Charles Mullighan\, MBBS (Hons)\, MSc\, MD. This position offers an unrivaled opportunity to be embedded in an environment leading integrated genomic and experimental studies in Leukemia. As part of our laboratory\, you will be involved in the integrative analysis of large cancer genomic datasets from patients with acute leukemia and related disorders. This involves the mapping and variant identification from large whole genome\, exome and transcriptome sequencing datasets\, and integration of such data to classify disease and predict outcome. Additional areas of work involve the analysis of epigenetic and ChIP sequencing data\, and analysis of clonal evolution in cancer. The data are derived from the largest ALL datasets from the St Jude Pediatric Cancer Genome Project\, the NCI TARGET initiative and projects initiated by Dr Mullighan.Candidates with deep understanding of cancer genomics\, genetics or epigenetics\, strong problem solving skills and expertise in next-generation sequencing data analysis are highly encouraged to apply. \n \n\n\n\nMinimum Education:\n\n\n\nPh.D. in molecular biology\, biochemistry\, computer science\, statistics\, mathematics\, bioinformatics or related field required \n \n\n\n\nMinimum Experience:\n\n\n\nPh.D which must include research related to bioinformatics (such as analysis of sequence data\, microarrays\, SNPs\, image data\, proteomics data\, or biological pathways; development of algorithms\, statistical methods\, or scientific software); OR If Ph.D with no bioinformatics research\, then two years of pre-or postdoctoral experience in computational biology or bioinformatics research is required \nExperience with programming languages such as Perl\, C\, or Java required \nExperience and knowledge on statistical analysis package such as R\, SAS and Matlab is highly desired.
URL:https://ces.b2sg.org/event/stjude-may2017/
LOCATION:St. Jude Children’s Hospital\, 262 Danny Thomas Pl\, Memphis\, TN\, 38105\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/05/stjude.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170524
DTEND;VALUE=DATE:20170625
DTSTAMP:20260819T012618
CREATED:20170524T104050Z
LAST-MODIFIED:20170524T104050Z
UID:18211-1495584000-1498348799@ces.b2sg.org
SUMMARY:Postdoctoral Research Fellow
DESCRIPTION:The Buck Institute is the only independent institute in the U.S. devoted solely to research on aging and age-related diseases such as Alzheimer’s\, Parkinson’s\, cancer\, arthritis\, diabetes\, and stroke. Our mission is to increase the healthspan\, the healthy years of life. Awarded a federal grant to establish interdisciplinary research in a new field called Geroscience\, Buck scientists work in a unique\, collaborative environment that allows scientists to initiate studies quickly and respond to new opportunities in fields such as stem cell research and regenerative medicine. Our scientists represent a variety of complementary fields\, including genetics\, epigenetics\, biochemistry\, molecular biology\, bioenergetics\, age-associated disease; and technological disciplines such as genomics\, proteomics\, protein interaction networks and bio-informatics. \n The Buck Institute\, which was designed by world famous architect I.M. Pei\, is located in Novato\, California\, 25 miles north of the Golden Gate Bridge. \n Receive training in specific area(s) of research with the aim of progressing towards an independent career. The appointment is for one year up to a usual maximum of three to four years\, each year contingent upon satisfactory progress\, as evaluated by the supervisor/mentor. \nKey Responsibilities: \n– Receive training in specific area(s) to continue the development of personal technical knowledge and research expertise.\n – Under guidance\, design\, plan and execute original research projects or major parts thereof.\n – Develop ability to critically evaluate and analyze data.\n – Keep a careful record of experiments in laboratory notebooks.\n – Publish and present data internally and externally.\n – Assist other institute researchers in areas of personal expertise.\n – Attend and participate in institutional programs\, seminars and lectures.\n – Progress towards an independent career.\n – Encouraged to seek outside training support.\n – Provide other related duties as required \nEducation: \n      PhD in relevant field of study \nPlease complete application and submit CV to be considered for this position.
URL:https://ces.b2sg.org/event/postdoctoral-research-fellow/
LOCATION:Buck Institute\, 8001 Redwood Boulevard\, Novato\, CA\, 94945\, United States
CATEGORIES:Jobs
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DTSTART;VALUE=DATE:20170524
DTEND;VALUE=DATE:20170625
DTSTAMP:20260819T012618
CREATED:20170524T111455Z
LAST-MODIFIED:20170524T112959Z
UID:18216-1495584000-1498348799@ces.b2sg.org
SUMMARY:Research Laboratory Technician Intermediate/Associate
DESCRIPTION:Seeking an experienced research associate who is energetic\, enthusiastic\, and enjoys collaborative and independent science. \nThe focus of the lab is stem cell biology and epigenetics. Since eye diseases are the first human disorders for which clinical trials for embryonic and induced pluripotent stem cell-derived tissue transplantation are being conducted\, you will be at the cutting edge of a technology important for regenerative medicine. \nThe primary job responsibility for this position is to move the research project forward through experimental work\, and coordinating work of others within the lab. Specific tasks include human and mouse stem cell\, primary\, or cancer cell culture\, immunohistochemistry\, PCR\, Western blotting\, transgenic mouse colony management\, laboratory and safety maintenance including ordering supplies. As part of their career development\, this person will learn from more experienced members of the laboratory specific assays relevant to the project. Other responsibilities based on interest and enthusiasm of the individual\, but adaptability to develop new protocols will be a requirement. \nDuties for this position include interdisciplinary interactions with Department of Pathology\, Pluripotent Stem Cell Cores\, as well as: \n\nHigh School Diploma or Associate’s Degree and 1-3 years experience required in field of biological sciences for the Intermediate level; High School Diploma or Associate’s Degree and up to 1 year experience required in field of biological sciences for the Associate level.\nHighly motivated\, detail oriented\, responsible individual with excellent communication and organizational skills who strives to work towards independence\, and is willing to teach others.\nPrevious laboratory experience (1 to 3 years) with molecular biology training (cloning\, PCR\, transfection\, transduction)\, mouse genotyping (PCR) and colony management\, western blotting\, immunohistochemistry\, protein immunoprecipitation\, viral transduction\, electroporation\, cloning.\nMust be proficient in Microsoft Office.\n\nDesired Qualifications \n\nPrevious laboratory experience with pluripotent stem cell culture (mouse and human) and use of CRISPR/Cas9 technology is required.\nPrevious laboratory experience in protein purification\, flow cytometry\, transgenic mouse colony management\, RNAi\, CRISPR/Cas9 gene editing\, RNA-seq/ChIP-seq and other genome wide assays\, bioinformatics\, and/or Python\, R language programming.\n\n\nWithin 0-10 years of terminal degree.\n\n\nBachelor’s degree in the biological sciences\, such as stem cells\, epigenetics\, bioinformatics\, cancer or a closely related field.
URL:https://ces.b2sg.org/event/research-laboratory-technician-intermediateassociate/
LOCATION:University of Michigan\, 500 S State St\, Ann Arbor\, MI\, 48109\, United States
CATEGORIES:Jobs
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