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X-WR-CALNAME:Cancer Epigenetics Society
X-ORIGINAL-URL:https://ces.b2sg.org
X-WR-CALDESC:Events for Cancer Epigenetics Society
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DTSTART:20170326T010000
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DTSTART:20171029T010000
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20170505
DTEND;VALUE=DATE:20170606
DTSTAMP:20260819T030932
CREATED:20170505T073927Z
LAST-MODIFIED:20170505T115245Z
UID:17828-1493942400-1496707199@ces.b2sg.org
SUMMARY:Research Associate II – Leukemia Lab
DESCRIPTION:A Research Associate II position is available in the Leukemia Research Laboratory of Gehr Family Center for Leukemia Research and the Beckman Research Institute of City of Hope. \nThe Center is supported by outstanding core facilities including\, but not limited to\, a large human and mouse leukemia tissue bank\, and GMP facilities for new drug development and exceptional Sequencing and Bioinformatics services. Our long-term goal is to elucidate the mechanisms of leukemogenesis and drug resistance of primitive leukemia cells\, and to identify novel therapeutic approaches in blood cancers. Our current research efforts are directed towards understanding the molecular and cellular pathways underlying the pathogenesis of acute myeloid leukemia (AML) using a combination of genetics\, genomics\, biochemistry\, proteomics\, molecular biology and cellular biology approaches. Our experimental systems include both genetic mouse models and primary leukemia stem cells from AML patients. The focus of this position is to understand the role of epigenetic changes in leukemia development\, progression and maintenance. \nPlease include a cover letter stating research interests and experiences\, curriculum vitae\, and names and contact information of three references. \nMinimum Education and Skills Required for Consideration: \n\nBachelor’s degree in biomedical related fields plus two years related research/laboratory experience.\nMaster’s degree in biomedical related fields preferred plus one year related research/laboratory experience preferred.\nMust be highly motivated with excellent organization and communication skills.\nCandidates with skills in molecular biology\, biochemistry\, tissue culture\, flow cytometry\, gene transfer\, mouse handling and transplantation techniques are preferred.\n\nAbout City of Hope \nCity of Hope\, an innovative biomedical research\, treatment and educational institution with over 4000 employees\, is dedicated to the prevention and cure of cancer and other life-threatening diseases and guided by a compassionate\, patient-centered philosophy. Founded in 1913 and headquartered in Duarte\, California\, City of Hope is a remarkable non-profit institution\, where compassion and advanced care go hand-in-hand with excellence in clinical and scientific research. City of Hope is a National Cancer Institute designated Comprehensive Cancer Center and a founding member of the National Comprehensive Cancer Network\, an alliance of the nation’s 20 leading cancer centers that develops and institutes standards of care for cancer treatment. \nCity of Hope is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race\, religion\, color\, national origin\, sex\, sexual orientation\, gender identity\, age\, status as a protected veteran\, or status as a qualified individual with disability.
URL:https://ces.b2sg.org/event/research-associate-ii-leukemia-lab/
LOCATION:Beckman Research Institute\, 1500 E Duarte Rd.\, Duarte\, CA\, 91741\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/png:https://ces.b2sg.org/wp-content/uploads/2017/02/City-of-hope.png
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170505
DTEND;VALUE=DATE:20170606
DTSTAMP:20260819T030932
CREATED:20170505T112515Z
LAST-MODIFIED:20170511T063443Z
UID:17829-1493942400-1496707199@ces.b2sg.org
SUMMARY:Postdoctoral Fellow- Oncology
DESCRIPTION:We seek a driven and accomplished postdoctoral fellow to join the cancer epigenetics group within the Oncology R&D (ORD) unit of Pfizer’s Worldwide R&D (WRD) division in La Jolla\, California. The successful candidate will collaborate with our cancer-immunopharmacology group to study the roles of epigenetic enzymes in anti-tumor immune responses. Guided by experienced mentors with strong academic track records\, the successful candidate will study fundamental questions in cancer immunology with the ultimate goal of publication in major scientific journals. Thus\, a strong scientific background with relevant expertise and documented accomplishments including significant publications is required. In addition\, the successful candidate will have a strong interest in translating results into novel immunotherapies for cancer. He/she will be highly self-motivated with a sense of urgency and focus on important problems. While driven to make strong individual contributions\, the successful candidate will also enjoy a highly interactive\, team-oriented environment and thrive by taking advantage of the significant multi-disciplinary resources available at Pfizer. This will be facilitated by the candidate’s excellent communication and interpersonal skills\, which complement strong work ethics and overall scientific excellence. \nResponsibilities \nPrimary Duties: \n\nWork independently and as part of teams to conceive\, design\, execute\, analyze/interpret\, and refine experiments ranging from biochemical and molecular assays\, in vitro and in vivo immunological functional assays in model systems\, and clinical sample analysis. Specific duties to include:\nContribute intellectually and at the bench to the conception\, design\, execution\, analysis\, interpretation and internal or external presentation of studies of epigenetic modulators of the anti-tumor immune response.\nKeep abreast with the literature and internal developments to become an expert point of contact for colleagues in the field of epigenetic immunopharmacology\nIndependently\, but with guidance by experienced mentors\, develop results into compelling stories for publication in major scientific journals and presentations on major scientific meetings and conferences\, both internally and externally\nApply genetic and pharmacologic approaches to modulate targets in vitro and in vivo to assess functional impacts on tumor cells and immune cells\, and on anti-tumor immune responses in syngeneic xenograft models and genetically engineered mutant mouse models of cancer. This will include CRISPR\, RNAi\, viral vector delivery\, transfection\, antibodies\, small molecules and other pharmacologic approaches to modulate targets.\nExecute secondary assays across various technology platforms – qRT-PCR\, immunoprecipitation\, ChIP-seq\, ATAC-seq\, FACS\, immunofluorescence\, western blotting\, ELISA\, high content screening\, etc.\nDevelop and apply complex in vitro assays for exploring target biology in tumor cells versus immune cells including T-cell functional assays\, co-culture assays\, ect.\nCollaborate with computational biology groups to analyze data including ChIP-seq\, RNA-seq\, ATAC-seq to support mechanism of action studies.\nEmploy computational and proteomic methods for tumor neoantigen prediction and functional validation\nUse electronic data capture/analysis tools such as Excel\, GraphPad\, Biobook\, Spotfire and PowerPoint for experimental documentation and data analysis/presentations.\nPresent research results and methodologies at weekly meetings with immediate supervisor and/or project leader\, and at meetings with members of the oncology research unit as appropriate.\nContribute to building a culture that embraces scientific excellence\, urgency\, partnerships with key stakeholders\, continuous learning and improvement\, increasing technical skill base and cancer biology expertise; take a proactive role in personal growth and scientific development.\n\nQualifications \nEducation and Experience: \n\nPh.D. in Cell Biology\, Molecular Biology\, or Immunology (or a comparable biological science) with a track record of scientific accomplishment as exemplified by significant scientific publications\nExperience with devising and implementing in vitro and in vivo immunological functional assays\nExperience in immuno-oncology and/or chromatin biology/epigenetics is desirable\nExperience in nucleic acid and protein extraction techniques and downstream analyses including quantitative RT-PCR\, immunoprecipitation (including ChIP)\, and immunoblotting.\nExperience with computational tools for antigen prediction\, NGS experiment design and data analyses\, including epigenomic data\, is desired\nAbility to work in a team environment; excellent written and oral communication skills in English; strong presentation skills and ability to discuss data at project team meetings.\nAble to master new concepts and techniques quickly.\nStrong attention to detail and organizational skills to manage projects in parallel\n\nPHYSICAL/MENTAL REQUIREMENTS: \nLifting\, sitting\, standing\, walking\, bending\, ability to perform mathematical calculations\, ability to read\, comprehend and process complex scientific matter\, and perform complex data analysis. Ability to travel by air\, water and ground. \nNON-STANDARD WORK SCHEDULE\, TRAVEL OR ENVIRONMENT REQUIREMENTS: \nAbility to accommodate non-standard work schedules due to experimental regimen or travel. Ability to adhere to safe work practices and wear full personal protective equipment. Ability to travel nationally and internationally. \nA career at Pfizer offers opportunity\, ownership and impact. All over the world\, Pfizer colleagues work together to positively impact health for everyone\, everywhere. Our colleagues have the opportunity to grow and develop a career that offers both individual and company success; be part of an ownership culture that values diversity and where all colleagues are energized and engaged; and the ability to impact the health and lives of millions of people. Pfizer\, a global leader in the biopharmaceutical industry\, is continuously seeking top talent who are inspired by our purpose to innovate to bring therapies to patients that significantly improve their lives. \nPfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race\, color\, religion\, sex\, sexual orientation\, age\, gender identity or gender expression\, national origin\, disability or veteran status. Pfizer also complies with all applicable national\, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.
URL:https://ces.b2sg.org/event/postdoc-oncology-pfizer/
LOCATION:Pfizer – La Jolla\, CA\, 10350 N Torrey Pines Rd\, La Jolla\, CA\, 92037\, United States
CATEGORIES:Jobs
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170506
DTEND;VALUE=DATE:20170607
DTSTAMP:20260819T030932
CREATED:20170506T044808Z
LAST-MODIFIED:20170506T072719Z
UID:17835-1494028800-1496793599@ces.b2sg.org
SUMMARY:Postdoc - epigenetic research
DESCRIPTION:A postdoctoral position is immediately available at the Vanderbilt University Genetics Institute and Department of Biochemistry. Our group is interested in the role of non-coding sequence variation in complex disease. Research in the Hodges Lab strives to understand how epigenetic features shape human genomes.  \nOur work aims to dissect the relationship between DNAmethylation and gene regulation\, particularly with respect to the gene regulatory activity of non-coding functional elements. We study this relationship on two levels; first\, we are interested in how DNA methylation states are established in differentiating cells. Second\, we are interested in the relationship between genotype and DNA methylation state (epitype). Projects in our lab address these questions utilizing innovative biochemical\, functional genomic and bioinformatic approaches. \nThe desired candidate should have a recent PhD in biochemistry\, genetics or related discipline\, with a strong molecular biology background. Experience with next-generation sequencing\, statistical genetics\, and bioinformatics is a priority. Please send CVs along with contact information for three references to emily.hodges@vanderbilt.edu.
URL:https://ces.b2sg.org/event/postdoc-gen-vanderbilt/
LOCATION:Vanderbilt University Genetics Institute and Department of Biochemistry\, 673B Light Hall\, Nashville\, TN\, 37205\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/png:https://ces.b2sg.org/wp-content/uploads/2017/05/venderbilt-u.png
ORGANIZER;CN="Emily%20Hodges":MAILTO:emily.hodges@vanderbilt.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170506
DTEND;VALUE=DATE:20170607
DTSTAMP:20260819T030932
CREATED:20170506T070545Z
LAST-MODIFIED:20170509T075251Z
UID:17839-1494028800-1496793599@ces.b2sg.org
SUMMARY:Research assistant II - prostate cancer epigenetics
DESCRIPTION:An exciting opportunity has been created for an experienced researcher to join the Alumkal Laboratory at the OHSU Knight Cancer Institute as a Research Assistant 2 in Portland\, OR. The individual will work with Dr. Joshi Alumkal\, Co-Leader of the OHSU Prostate Cancer Research Program.  Our laboratory focuses on identifying mechanisms by which key chromatin modifying enzymes and chromatin readers drive transcription of pathways that promote treatment resistance. We use genomics studies in prostate cancer clinical samples and prostate cancer cell line model systems and functional studies to understand this process. Our goal is to develop new\, targeted treatment strategies for men with advanced prostate cancer. \nThe Research Assistant 2 will be responsible for carrying out experiments in the laboratory\, helping with ordering supplies\, and participating in research to study cancer epigenetics and drug resistance in prostate cancer. Their duties will also include performing mouse xenograft tumor growth experiments with drug injections or drug gavage\, basic molecular biology techniques including cell culture\, DNA/RNA/protein extraction\, QPCR\, Western blots\, maintaining meticulous records of experimental procedures\, and preparing material for presentation and/or submission to peer reviewed publications. \nRequired Qualifications: \n\nBachelor’s degree with major courses in field of research and no experience\, Or an AA/RN and 2 years of experience\nAbility to prioritize multiple tasks at one time\nExcellent verbal and written communication skills\nExcellent analytical and organizational skills\nAbility to work independently and as part of a team while being collaborative in resolving problems\nProficient with computers running Windows software such a MS Excel\, Access\, Word and PowerPoint\nExcellent customer service skills both on the phone and in person\nEnergy and drive to coordinate multiple projects simultaneously\nAbility to use tact and diplomacy to maintain effective working relationships\nWorking knowledge of basic molecular biology techniques: PCR\, DNA/RNA extraction\nProficiency with mammalian cell culture\nAble to perform the essential functions of the position with or without accommodation\n\nPreferred Qualifications: \n\n2 years of experience in a molecular biology setting\nExpertise with recombinant DNA techniques\, Western blots\, and RNAi/plasmid transfections\nRodent handling experience\, especially with xenograft tumor growth experiments involving injection and/or gavage treatment\n\nWork schedule\, hours\, salary range and FTE: \n\nFTE: 1.0 FTE\, Full Time\nSchedule: Monday – Friday\, with occasional night and weekend hours\nSalary Range: $30\,638 – $40\,000\nLocation: Portland\, OR (South Waterfront)\nJob Type: Research\n\nOregon Health & Science University values a diverse and culturally competent workforce. We are proud of our commitment to being an equal opportunity\, affirmative action organization that does not discriminate against applicants on the basis of any protected class status\, including disability status and protected veteran status. Individuals with diverse backgrounds and those who promote diversity and a culture of inclusion are encouraged to apply. To request reasonable accommodation contact the Affirmative Action and Equal Opportunity Department at 503-494-5148 or aaeo@ohsu.edu. \nPlease be sure to upload a Cover Letter and Resume or CV when applying online.
URL:https://ces.b2sg.org/event/research-assistant-ii-prostate-cancer-epigenetics/
LOCATION:OHSU\, 3181 SW Sam Jackson Park Rd\, Portland\, OR\, 97239\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/05/ohsu-e1494316350889.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170509
DTEND;VALUE=DATE:20170610
DTSTAMP:20260819T030932
CREATED:20170509T043559Z
LAST-MODIFIED:20170509T044746Z
UID:17916-1494288000-1497052799@ces.b2sg.org
SUMMARY:Postdoctoral Associate - cancer epigenetics
DESCRIPTION:A Postdoctoral Associate position is available in the Dan L Duncan Comprehensive Cancer Center to perform bioinformatics data analysis to understand epigenetic gene regulation and transcription dynamics in various biological processes and disease models including cancer. bioinformatics can address such problems at the systems level. Develop and test novel bioinformatics algorithms in many areas spanning epigenomics and transcriptomics – in the context of stem cells\, cancer and aging. \nIdeal candiates should have a PhD in a quantitative field\, strong programming skills (Python/Perl\, R\, C/C++) and/or large-scale data analysis skills. Substantial experience in Bioinformatics/Computational Biology is a plus. A non-bioinformatics background with strong training in other areas (e.g.\, physics or computer science) will also be considered.
URL:https://ces.b2sg.org/event/postdoc-bcm-may2017/
LOCATION:Baylor College of Medicine\, 1 Baylor Plaza\, Houston\, TX\, 77030\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/05/bcm-baylor-e1494304823632.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170509
DTEND;VALUE=DATE:20170610
DTSTAMP:20260819T030932
CREATED:20170509T050512Z
LAST-MODIFIED:20170509T051255Z
UID:17921-1494288000-1497052799@ces.b2sg.org
SUMMARY:Research Specialist A - Cancer Epigenetics
DESCRIPTION:The candidate will work in the High-Throughput Screening Core (HTSC) in the Perelman School of Medicine (PSOM). He/she will work with the Scientific and Technical Directors of the core to further design\, to optimize and validate biological assays in high-density formats (i.e. 384 well microtiter plates) for primary human cancers that can be screened against libraries of FDA approved drugs\, as part of a collaborative research initiative between the Chemogenomic Discovery Program\, Precision Medicine\, and Hospital of University of Pennsylvania. The candidate will also dedicate effort to high-throughput cell based screens designed to dissect the role of epigenetics in cellular senescence.  \nSpecific responsibilities will include moderately complex procedures/techniques in eukaryotic/mammalian cell-culture\, molecular biology\, cell biology\, and high-throughput genetic/chemical screening. The candidate will operate and maintain automated laboratory robotic workstations related to high-throughput screening; prepare and manage libraries of siRNA\, shRNA\, cDNA\, CRISPR and drug-like small molecule libraries for high-throughput screening; and analyze\, interpret\, and prepare reports of large data sets. Additional responsibilities will include literature searches\, maintaining articulate documentation of daily tasks and maintenance of the laboratory’s databases/logs and inventory (i.e. supplies\, reagents\, and equipment). \nA Bachelor’s Degree and 0 to 1 year of experience or equivalent combination of education and experience is required. 1 to 3 years of experience preferred.  The ideal candidate will have strong organizational skills\, effective communication skills; and the ability to problem-solve and work independently. The applicant should have basic understanding of cell biology\, molecular biology and biochemistry. Experience in bioinformatics and programming is desirable. \nThe University of Pennsylvania\, the largest private employer in Philadelphia\, is a world-renowned leader in education\, research\, and innovation. This historic\, Ivy League school consistently ranks among the top 10 universities in the annual U.S. News & World Report survey. Penn has 12 highly-regarded schools that provide opportunities for undergraduate\, graduate and continuing education\, all influenced by Penn’s distinctive interdisciplinary approach to scholarship and learning. \nPenn offers a unique working environment within the city of Philadelphia. The University is situated on a beautiful urban campus\, with easy access to a range of educational\, cultural\, and recreational activities. With its historical significance and landmarks\, lively cultural offerings\, and wide variety of atmospheres\, Philadelphia is the perfect place to call home for work and play. \nThe University offers a competitive benefits package that includes excellent healthcare and tuition benefits for employees and their families\, generous retirement benefits\, a wide variety of professional development opportunities\, supportive work and family benefits\, a wealth of health and wellness programs and resources\, and much more.
URL:https://ces.b2sg.org/event/research-specialist-penn-may2017/
LOCATION:University of Pennsylvania\, 3400 Civic Center Blvd\, Philadelphia\, 19104\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/05/penn-1-e1494306554396.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170510
DTEND;VALUE=DATE:20170611
DTSTAMP:20260819T030932
CREATED:20170510T095035Z
LAST-MODIFIED:20170510T101423Z
UID:17945-1494374400-1497139199@ces.b2sg.org
SUMMARY:Postdoctoral Associate - Stem Cell Biology and Cancer Epigenetics
DESCRIPTION:An academic postdoctoral associate position is available in the laboratory of Dr. Jennifer Trowbridge to study epigenetic mechanisms governing hematopoietic stem cell lineage commitment\, and how deregulation of epigenetic modifications leads to myeloproliferative disorders including leukemia (http://trowbridgelab.com). \nThe Jackson Laboratory (JAX) offers a unique research and training environment characterized by multidisciplinary scientific collaboration\, unparalleled mouse resources\, outstanding core services\, and is located adjacent to Acadia National Park in coastal Maine. Translational research collaborations in genomics-based\, personalized medicine are fostered through our new JAX Genomic Medicine campus in Farmington\, CT. In addition to lab-based training\, JAX has developed a unique program for trainees to expand their professional skills in science communication\, entrepreneurship\, teaching\, mentoring and laboratory management to best prepare postdocs for future career opportunities. \nRequired Skills \nAbility to plan\, execute and analyze an independent research project as well as exceptional verbal and written communication skills. Preference given to self-motivated and career oriented individuals. \nRequired Experience \nA Ph.D. in biological or related sciences is required\, and a strong training background in molecular biology\, cell biology and/or epigenetics is preferred. \nApply by submitting a cover letter describing past research accomplishments\, research interests and career aspirations\, a current CV\, and the names of three references\, as one PDF file.
URL:https://ces.b2sg.org/event/postdoc-jackson-lab-10may2017/
LOCATION:Jackson Laboratory\, 600 Main Street\, Bar Harbor\, ME\, 04609\, United States
CATEGORIES:Jobs
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170510
DTEND;VALUE=DATE:20170611
DTSTAMP:20260819T030932
CREATED:20170510T110603Z
LAST-MODIFIED:20170510T112119Z
UID:17948-1494374400-1497139199@ces.b2sg.org
SUMMARY:Research Associate I - Cancer Epigenetics
DESCRIPTION:Duties:  \n\nOpening for a temporary Scientific Researcher in the Discovery Oncology Department\, to discover and validate new targets in cancer biology.\nShe/he will utilize and/or develop state of the art genetic\, epigenetic and proteomic technologies to characterize exciting oncology drug targets in the epigenetics space.\nThe successful candidate will be expected to work creatively\, independently and collaboratively.\n\nSkills:  \n\nAn ideal candidate should have a strong background in Cancer Biology and will possess the proven ability to work independently.\nHe/she should have technical skills in molecular and cellular biology.\nIn particular\, FACS\, western blotting\, cloning\, genetic manipulation of cell lines and cell culture\, cell imaging and growth analysis.\nExperience with techniques related to the study of chromatin\, epigenetics and Next Generation Sequencing is also an advantage.\nStrong organizational skills and the ability to work independently in a team environment are required.\nExcellent communication skills\, both written and verbal are essential.\n\nEducation:  \n\nA Bachelors or Masters degree with 3+ years of cancer research experience.
URL:https://ces.b2sg.org/event/research-associate-apex/
LOCATION:Apex Life Sciences\, South San Francisco \, CA\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/png:https://ces.b2sg.org/wp-content/uploads/2017/05/apex-e1494414486257.png
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170511
DTEND;VALUE=DATE:20170612
DTSTAMP:20260819T030932
CREATED:20170511T062816Z
LAST-MODIFIED:20170511T063321Z
UID:17952-1494460800-1497225599@ces.b2sg.org
SUMMARY:Senior Scientist - Oncology Target Discovery
DESCRIPTION:We are seeking a highly motivated scientist to join the Oncology Therapeutic Discovery Group in Pfizer’s Oncology Research Unit. The successful applicant will assist in the identification and validation of novel small molecule drug targets in the areas of cancer epigenetics\, signal transduction\, metabolism\, and immuno-oncology.  \nThe successful candidate will work independently as part of a research team that is focused on identifying and validating novel drug targets and drug combinations in the fields of cancer biology and immuno-oncology. He/She will take a proactive role in their personal growth and scientific development.  \nThe candidate is expected to \n– utilize expertise in cancer biology and molecular/cellular immunology to design\, execute\, and analyze/interpret experiments and functional genomic screens to uncover novel areas of cancer biology and /or genes that can be exploited therapeutically.\n– Present research results and methodologies at weekly/monthly group meetings and at meetings with members of the Oncology Research Unit.\n– Contribute to building a culture that embraces scientific excellence\, urgency\, partnerships with key stakeholders\, and continuous learning and improvement.  \nSpecific technical duties include:  \n– Applying genetic and pharmacologic approaches to modulate targets in vitro and assessing the functional impact on cancer initiation and progression. These include RNAi\, CRISPR\, small molecules\, antibodies and other pharmacologic approaches to modulate targets in vitro.\n– Implementing genetic and pharmacological screens to identify new targets and potential drug combinations.\n– Utilizing expertise in cancer biology to design\, execute\, and analyze/interpret experiments to advance mechanism-of-action target biology and develop innovative approaches for targeting in cancer.\n– Utilizing 2D or 3D (spheroid models\, co-culture systems\, etc) assays to measure cell proliferation\, cytokine\, or phenotypic readouts\n– Executing high content functional assays using Cellomics or Opera Confocal Fluorescent based assays.\n– Executing molecular and cell-based assays across various technology platforms to assess target modulation and measure downstream signaling pathways- qPCR\, ChIP-seq\, FACS\, immunofluorescence\, western blotting\, ELISA\, high content screening\, etc.\n– Collaborating with in vivo pharmacologists to perform in vivo efficacy and biomarker studies.\n– Utilizing electronic data capture/analysis tools such as Excel\, GraphPad\, Biobook\, Spotfire and PowerPoint for experimental documentation and data analysis/presentations. \nQualifications  \n– Education and Experience: PhD or MD PhD in Molecular Biology\, Cell Biology\, Epigenetics or Immunology (or a comparable biological science) with a minimum of 2-5 years of post-doctoral experience.\n– At least 5 years of experience working in the field of cancer biology or immunology\n– At least 2-5 years of experience in the postdoctoral/industry setting focused on target identification and validation\n– Extensive experience with genetic and/or pharmacological screens (in vitro or in vivo) – Hands on\, extensive experience working with human or murine CAR T\, CD8/CD4 or other immuno-specific cell lines\n– Ability to work in a team environment Technical Skills: – Strong track record in target identification/ validation and screening approaches using small-molecule inhibitors and/or genetic manipulation (shRNA\, CRISPR\, etc) is required\n– Strong biological and technical knowledge related to immune cell biology\, mechanism of action target validation assays\, T cell signaling and regulation is required\n– Expertise in immune and mammalian cell culture techniques required\n– Preference for candidates with also expertise in phenotypic analysis of immuno-oncology targets and pathways\n– Strong experience working as part of a cross-functional team\n– Excellent verbal/written communication and interpersonal skills Physical/Mental Requirements: Extended periods of sitting and standing
URL:https://ces.b2sg.org/event/senior-scientist-pfizer-may2017/
LOCATION:Pfizer – Pearl River\, NY\, 401 North Middletown Road\, Pearl River\, NY\, 10965\, United States
CATEGORIES:Jobs
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170511
DTEND;VALUE=DATE:20170612
DTSTAMP:20260819T030932
CREATED:20170511T071344Z
LAST-MODIFIED:20170511T072355Z
UID:17959-1494460800-1497225599@ces.b2sg.org
SUMMARY:Associate Director / Senior Scientist - Cancer Immunotherapy
DESCRIPTION:Fate’s Cancer Immunotherapy group is seeking a talented and highly motivated scientist with expertise in oncology and stroma immunobiology to join a multidisciplinary team dedicated to the discovery of novel cellular therapeutics for the treatment of cancer.  The successful candidate will play a leading role in the research and translation of new biologic modalities for off-the-shelf cancer immunotherapy.  Specifically\, the candidate will be tasked to drive ongoing efforts to identify novel strategies to improve effector persistence across tumor microenvironment and histocompatibility barrier.  The candidate must have in depth knowledge of NK cell and T cell immunology\, cancer biology\, effector cell dysfunction and exhaustion\, immunosuppression\, metabolism and trafficking. The position will require independent research as well as coordination with the greater cancer immunotherapy and cellular engineering groups. This is a full-time position reporting to the Vice President of Cancer Immunotherapy and is located at our corporate headquarters in San Diego\, CA. \nResponsibilities\n •   Identification and implementation of novel genetic and epigenetic programming and engineering strategies to improve safety and efficacy of universal cancer immunotherapy products\n •   Present research initiatives to management team and drive execution of sanctioned programs\n •   Execute research timelines to meet program and corporate objectives\n •   Scientific team management \nRequirements\n•   PhD in cell biology\, immunology or related field\n•   Minimally 4-5 years post-doctoral training with additional 3-5 years continuing experience in academia or industry\n•   Extensive experience in analyzing the interaction of hematopoietic cells\, tumor cells and microenvironment using both in vitro and in vivo functional models\n•   Expert in flow cytometry\, imaging based approaches\, cellular cytotoxicity assays and metabolism assessment to determine the biological mechanisms and activities of programmed cells\n•   Demonstration of ability to work both independently and dependently within a goal-oriented team environment\n•   Strong scientific track-record demonstrating experience and expertise in cancer immunotherapy or related fields \nWorking Conditions and Physical Requirements\n •   Will require working with blood and cell lines of human origin\n •   Will require working with rodent models\n •   100% on-site work at corporate headquarters in San Diego\, CA\n •   Evening and weekend work as necessary \nThe preceding job description indicates the general nature and level of work performed by employees within this classification. Additional and incidental duties related to the primary duties may be required from time to time. \nFor consideration send cover letter and resume to:  careers@fatetherapeutics.com and reference job code 164BV.
URL:https://ces.b2sg.org/event/fate-therapeutic-may2017/
LOCATION:Fate Therapeutics\, 3535 General Atomics Ct #200\, San Diego\, CA\, 92121\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/05/Fate-Therapeutics-1.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170511
DTEND;VALUE=DATE:20170612
DTSTAMP:20260819T030932
CREATED:20170511T115141Z
LAST-MODIFIED:20170511T172300Z
UID:17968-1494460800-1497225599@ces.b2sg.org
SUMMARY:Postdoctoral Scientist - Cancer Epigenetics
DESCRIPTION:A position is available for a Postdoctoral Scientist in the laboratory of Dr. Katherine Chiappinelli\, Ph. D. at the George Washington Cancer Center (https://smhs.gwu.edu/cancercenter/) in the Department of Microbiology\, Immunology\, & Tropical Medicine (https://smhs.gwu.edu/microbiology/) at George Washington University. Dr. Chiappinelli’s laboratory focuses on the epigenetic control of gene expression in cancer\, specifically of immune signaling in and from tumor cells. Our goal is to use epigenetic therapies to harness the power of the immune system to fight cancer. This position will assist in design\, evaluation\, and conducting experiments and research while receiving advanced training from the Principal Investigator to enhance professional skills and research independence. \nResponsibilities include: \n •Designs\, evaluates and conducts experiments.\n •Assists in the development of new ideas that promote current research.\n •Prepares and publishes scientific manuscripts.\n •Works closely with students and supervises research staff as necessary.\n •Operates specific equipment and train other laboratory personnel.\n •Performs other work related duties as assigned. The omission of specific duties does not preclude the supervisor from assigning duties that are logically related to the position. \nMinimum Qualifications: \nRequires a PhD in the field or in a related area. \nPreferred Qualifications:  \n•Impeccable aseptic technique and strong molecular biology skills (basic tissue culture\, PCR\, molecular cloning\, RNA extraction and analysis). \n •Experience in one or more of the following areas: biochemistry (protein purification and analysis\, in vitro assays\, etc.)\, genetics (genetic manipulation through CRISPR knockout\, shRNA knockdown\, etc.)\, gene expression and bioinformatics (analysis of local and global gene expression data)\, and cell biology (fluorescence microscopy\, flow-cytometry\, etc)\n •Experience working with laboratory animals is preferred. \n •Ability to prepare research for publication and present at scientific meetings. \n •Excellent organizational and communication skills.
URL:https://ces.b2sg.org/event/postdoc-scientist-gwu-may2017/
LOCATION:George Washington University\, 2121 I St NW\, Washington\, DC\, 20052\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170512
DTEND;VALUE=DATE:20170613
DTSTAMP:20260819T030932
CREATED:20170512T090556Z
LAST-MODIFIED:20170513T074332Z
UID:17973-1494547200-1497311999@ces.b2sg.org
SUMMARY:Postdoctoral Associate
DESCRIPTION:A position of Post-Doctoral Associate is opened in University of Pittsburgh School of Medicine to seek a motivated person to study the genomics of human cancers and to develop cancer treatment using genome targeting strategy. Two years of experience in molecular biology and cell biology are required. Candidates must possess a Ph.D. or M.D./Ph.D degree. Interested candidate should submit their inquiry and CV to Dr. Jianhua Luo\, M.D.\, Ph.D. at luoj@upmc.edu. Salary will be commensurate with experience.
URL:https://ces.b2sg.org/event/postdoctoral-associate/
LOCATION:University of Pittsburgh School of Medicine\, 3550 Terrace St\, Pittsburgh\, PA\, 15213\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170513
DTEND;VALUE=DATE:20170614
DTSTAMP:20260819T030932
CREATED:20170513T072628Z
LAST-MODIFIED:20170513T072728Z
UID:17981-1494633600-1497398399@ces.b2sg.org
SUMMARY:Research Scientist
DESCRIPTION:Dr. Kapil N. Bhalla is currently seeking a Research Scientist who will be responsible for conducting research in his NIH-funded laboratory. The focus of the basic and translational research in this laboratory includes the biology and developmental therapeutics related to epigenetic mechanisms involving histone deacetylases\, methyltransferases and demethylases\, BET proteins\, as well as the chaperone biology of heat shock proteins and their cancer relevant client proteins regulating cell growth\, differentiation and survival of the human leukemia stem/progenitor cells. \nThe preferred candidate will possess a Ph.D. in Biology\, Biological Sciences\, Life Sciences or related field; a keen interest and experience in cancer research and excellent English skills (both written and verbal).  The preferred candidate will have completed at least a 3 year Post-doctoral fellowship in an area relevant to the focus of research in Dr. Bhalla’s laboratory. In addition\, have the ability to troubleshoot in the design and conduct the laboratory studies. Experience in molecular studies involving gene transfection\, analysis of gene expression through QPCR\, microarrays\, immunoblots and flow cytometry\, as well as experience in chromatin immunoprecipitation studies\, evaluation of protein biochemistry with 2D gels and the yeast-two-hybrid system\, and tissue culture techniques is required. Experience in the ability to utilize CRISPR technology for gene editing and to utilize confocal microscopy for molecular imaging is highly desired. Experience in xenograft and genetically-engineered animal models of cancer and/or leukemia\, and confocal microscopy is also desired.  An outstanding research environment\, new laboratory and core facilities are provided. \nKEY FUNCTIONS \n1. The basic and translational research focus of this laboratory includes epigenetic mechanisms involving histone deacetylases\, methyltransferases and demethylases\, heat shock proteins and their cancer and leukemia-relevant client proteins\, as well as transfection and functional analyses of genes regulating cell death/survival of human cancer cells. Experience in animal studies involving NOD/SCID or nude mice\, and mouse imaging (xenogen and MRI) is highly desirable. Experience in molecular techniques involving plasmid DNA preparations and transfection\, the analysis of gene expression including QPCR\, microarrays\, chromatin immunoprecipitation\, evaluation of protein biochemistry with 2D gels\, animal models\, the yeast-two-hybrid system\, confocal microscopy and tissue culture are also preferred. \n2. Plans\, organizes\, coordinates\, directs\, and participates in scientific research projects.  \nPerforms quality research in relation to current research projects\, and other identified needs. Interprets results of experiments\, and makes necessary changes in procedures when needed.  Compiles data sheets. \n3. Organizes and performs routine procedures involving molecular biology and biochemistry of RNA processing. Requires experience in tissue culture\, DNA & RNA preparation\, PCR\, DNA cloning\, protein synthesis and electrophoresis.    Responsible for providing laboratory services\, tissue culture\, processing research samples\, and/or cataloging samples as required. Interacts with the principal investigators\, postdoctoral fellows and other research personnel in communicating experimental design and results. \n4. Requires knowledge of standard radiographic techniques. Dark room usage is essential as is use and proper handling of radioisotopes. \nMust be able to comply with all institutional safety policies including Universal Precautions and OSHA standards when handling toxic\, hazardous\, flammable\, or potentially infectious or carcinogenic materials.  This may require wearing common protective garments or equipment such as gloves\, eye protection\, face mask\, gown or lab coat\, etc.  Additionally some procedures may require the use of a fume hood or biological safety cabinet. \n5. Work with laboratory animals such as mice and rats and to perform interventional procedures such as tail vein injections and orthotopic implantations. Retrieves\, maintains\, and catalogs specimen stocks from outside reference laboratories.  Assists in other laboratory activities as needed. \n6. Performs and coordinates scientific experiments in a collaborative effort with other technicians\, postdoctoral fellows\, and staff members.  Monitors work flow as it pertains to the need for supplies\, equipment maintenance and stock solutions.  Performs preventive maintenance on laboratory equipment. \n7. Equipment monitoring on a daily basis verifying correct temperatures of freezers\, refrigerators\, incubators\, etc.  Equipment maintenance on a weekly basis includes cleaning and disinfecting refrigerators and incubators.  Daily counter clean up and disinfection to ensure safety of the laboratory work place.  Bags waste and transports to appropriate refuse area utilizing safety standards and guidelines.  Maintains all safety precautions. \n8. Assigns and reviews work of subordinates\, determines specific goals or objectives to be attained\, evaluates resulting research data\, and revises techniques or approaches to work problems. Supervises the design\, development\, or adapting of equipment used in experiments or research to obtain desired results. Utilizes institutional and departmental databases to perform data retrieval for analysis.  Designs retrieval templates for standard queries.  Apply bio-statistical methods in analyzing clinical data such as pretreatment characteristics\, response to treatment\, toxicities\, and mortality\, etc.  \nConducts Library Work.  Finds and copies journal articles as required.  Reads and understands articles related to ongoing research.  Maintains references in a manual filing system.  Requires good reading and comprehension skills as well as diligence\, patience and ability to carry several heavy books at a time. \n9. Assemble samples\, reagents\, dry or wet ice\, data and packaging materials; draft a cover letter\, accurately and legibly fill out shipping labels; carry package to receiving area on ground floor prior to pick up.  Keep accurate legible logs of outgoing and incoming packages.  For incoming packages\, ascertain contents\, store at appropriate location\, file information sheets and notify principal investigator.  Update pertinent inventory logs. \n10. Compiles\, writes\, and submits reports to superior.  Plans and supervises the training of technicians and other laboratory personnel with respect to proper laboratory techniques\, the use of laboratory equipment\, and safety procedures. \n11. Presents findings of data to PI and prepares scientific documents for publication.  Presents findings of research projects to professional groups and prepares scientific documents for publication.  \n12. Performs related work as required. \nsource:sonj \n\nEDUCATON \nRequired: PhD in one of the natural sciences or related field or Medical degree \n  \nEXPERIENCE \nRequired: With PhD\, no experience required. With Medical degree\, two years of experience in experimental or scientific work. \nPreferred: Completion of a 3 year post-doctoral fellowship.
URL:https://ces.b2sg.org/event/researcher2-mdanderson-may2017/
LOCATION:MD Anderson Cancer Center\, 1515 Holcombe Blvd\, Houston\, TX\, 77030\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170523
DTEND;VALUE=DATE:20170624
DTSTAMP:20260819T030932
CREATED:20170523T125818Z
LAST-MODIFIED:20170617T065128Z
UID:18207-1495497600-1498262399@ces.b2sg.org
SUMMARY:Bioinformatics Research Scientist
DESCRIPTION:A Bioinformatics Research Scientist position is available in the lab of Dr. Charles Mullighan\, MBBS (Hons)\, MSc\, MD. This position offers an unrivaled opportunity to be embedded in an environment leading integrated genomic and experimental studies in Leukemia. As part of our laboratory\, you will be involved in the integrative analysis of large cancer genomic datasets from patients with acute leukemia and related disorders. This involves the mapping and variant identification from large whole genome\, exome and transcriptome sequencing datasets\, and integration of such data to classify disease and predict outcome. Additional areas of work involve the analysis of epigenetic and ChIP sequencing data\, and analysis of clonal evolution in cancer. The data are derived from the largest ALL datasets from the St Jude Pediatric Cancer Genome Project\, the NCI TARGET initiative and projects initiated by Dr Mullighan.Candidates with deep understanding of cancer genomics\, genetics or epigenetics\, strong problem solving skills and expertise in next-generation sequencing data analysis are highly encouraged to apply. \n \n\n\n\nMinimum Education:\n\n\n\nPh.D. in molecular biology\, biochemistry\, computer science\, statistics\, mathematics\, bioinformatics or related field required \n \n\n\n\nMinimum Experience:\n\n\n\nPh.D which must include research related to bioinformatics (such as analysis of sequence data\, microarrays\, SNPs\, image data\, proteomics data\, or biological pathways; development of algorithms\, statistical methods\, or scientific software); OR If Ph.D with no bioinformatics research\, then two years of pre-or postdoctoral experience in computational biology or bioinformatics research is required \nExperience with programming languages such as Perl\, C\, or Java required \nExperience and knowledge on statistical analysis package such as R\, SAS and Matlab is highly desired.
URL:https://ces.b2sg.org/event/stjude-may2017/
LOCATION:St. Jude Children’s Hospital\, 262 Danny Thomas Pl\, Memphis\, TN\, 38105\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170524
DTEND;VALUE=DATE:20170625
DTSTAMP:20260819T030932
CREATED:20170524T104050Z
LAST-MODIFIED:20170524T104050Z
UID:18211-1495584000-1498348799@ces.b2sg.org
SUMMARY:Postdoctoral Research Fellow
DESCRIPTION:The Buck Institute is the only independent institute in the U.S. devoted solely to research on aging and age-related diseases such as Alzheimer’s\, Parkinson’s\, cancer\, arthritis\, diabetes\, and stroke. Our mission is to increase the healthspan\, the healthy years of life. Awarded a federal grant to establish interdisciplinary research in a new field called Geroscience\, Buck scientists work in a unique\, collaborative environment that allows scientists to initiate studies quickly and respond to new opportunities in fields such as stem cell research and regenerative medicine. Our scientists represent a variety of complementary fields\, including genetics\, epigenetics\, biochemistry\, molecular biology\, bioenergetics\, age-associated disease; and technological disciplines such as genomics\, proteomics\, protein interaction networks and bio-informatics. \n The Buck Institute\, which was designed by world famous architect I.M. Pei\, is located in Novato\, California\, 25 miles north of the Golden Gate Bridge. \n Receive training in specific area(s) of research with the aim of progressing towards an independent career. The appointment is for one year up to a usual maximum of three to four years\, each year contingent upon satisfactory progress\, as evaluated by the supervisor/mentor. \nKey Responsibilities: \n– Receive training in specific area(s) to continue the development of personal technical knowledge and research expertise.\n – Under guidance\, design\, plan and execute original research projects or major parts thereof.\n – Develop ability to critically evaluate and analyze data.\n – Keep a careful record of experiments in laboratory notebooks.\n – Publish and present data internally and externally.\n – Assist other institute researchers in areas of personal expertise.\n – Attend and participate in institutional programs\, seminars and lectures.\n – Progress towards an independent career.\n – Encouraged to seek outside training support.\n – Provide other related duties as required \nEducation: \n      PhD in relevant field of study \nPlease complete application and submit CV to be considered for this position.
URL:https://ces.b2sg.org/event/postdoctoral-research-fellow/
LOCATION:Buck Institute\, 8001 Redwood Boulevard\, Novato\, CA\, 94945\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170524
DTEND;VALUE=DATE:20170625
DTSTAMP:20260819T030932
CREATED:20170524T111455Z
LAST-MODIFIED:20170524T112959Z
UID:18216-1495584000-1498348799@ces.b2sg.org
SUMMARY:Research Laboratory Technician Intermediate/Associate
DESCRIPTION:Seeking an experienced research associate who is energetic\, enthusiastic\, and enjoys collaborative and independent science. \nThe focus of the lab is stem cell biology and epigenetics. Since eye diseases are the first human disorders for which clinical trials for embryonic and induced pluripotent stem cell-derived tissue transplantation are being conducted\, you will be at the cutting edge of a technology important for regenerative medicine. \nThe primary job responsibility for this position is to move the research project forward through experimental work\, and coordinating work of others within the lab. Specific tasks include human and mouse stem cell\, primary\, or cancer cell culture\, immunohistochemistry\, PCR\, Western blotting\, transgenic mouse colony management\, laboratory and safety maintenance including ordering supplies. As part of their career development\, this person will learn from more experienced members of the laboratory specific assays relevant to the project. Other responsibilities based on interest and enthusiasm of the individual\, but adaptability to develop new protocols will be a requirement. \nDuties for this position include interdisciplinary interactions with Department of Pathology\, Pluripotent Stem Cell Cores\, as well as: \n\nHigh School Diploma or Associate’s Degree and 1-3 years experience required in field of biological sciences for the Intermediate level; High School Diploma or Associate’s Degree and up to 1 year experience required in field of biological sciences for the Associate level.\nHighly motivated\, detail oriented\, responsible individual with excellent communication and organizational skills who strives to work towards independence\, and is willing to teach others.\nPrevious laboratory experience (1 to 3 years) with molecular biology training (cloning\, PCR\, transfection\, transduction)\, mouse genotyping (PCR) and colony management\, western blotting\, immunohistochemistry\, protein immunoprecipitation\, viral transduction\, electroporation\, cloning.\nMust be proficient in Microsoft Office.\n\nDesired Qualifications \n\nPrevious laboratory experience with pluripotent stem cell culture (mouse and human) and use of CRISPR/Cas9 technology is required.\nPrevious laboratory experience in protein purification\, flow cytometry\, transgenic mouse colony management\, RNAi\, CRISPR/Cas9 gene editing\, RNA-seq/ChIP-seq and other genome wide assays\, bioinformatics\, and/or Python\, R language programming.\n\n\nWithin 0-10 years of terminal degree.\n\n\nBachelor’s degree in the biological sciences\, such as stem cells\, epigenetics\, bioinformatics\, cancer or a closely related field.
URL:https://ces.b2sg.org/event/research-laboratory-technician-intermediateassociate/
LOCATION:University of Michigan\, 500 S State St\, Ann Arbor\, MI\, 48109\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170601
DTEND;VALUE=DATE:20170702
DTSTAMP:20260819T030932
CREATED:20170601T164205Z
LAST-MODIFIED:20170601T164504Z
UID:18242-1496275200-1498953599@ces.b2sg.org
SUMMARY:Associate Researcher - Oncological Sciences
DESCRIPTION:What You’ll Do:  \nHighly motivated scientists who will be working as part of a multidisciplinary team\, composed of Molecular Cancer and Computational biologists. Field of research is molecular oncology\, specifically we will dissect the role of Methyltransferases in tumor initiation and maintenance. \n \nWhat You’ll Bring:\n\nStrong background in Molecular Biology\, Epigenetic mechanisms of gene regulation\, Genomics is appreciated.\n\nMust have a positive attitude towards team work\, and be self-motivated and well organized.\n\n\nMount Sinai Health System’s multidisciplinary clinical research teams are pioneering innovative new approaches in health care across a variety of fields. Working alongside leading physicians and within internationally acclaimed medical institutes\, centers\, and laboratories\, our scientists continue to shape the future of clinical care and improve outcomes for patients of all ages.  \nAre you ready to discover the world of limitless possibilities that comes with wearing the badge? Explore more about this opportunity and how you can help us write a new chapter in our story of unrivaled patient care!
URL:https://ces.b2sg.org/event/associate-researcher-oncological-sciences/
LOCATION:Mount Sinai – Icahn School of Medicine\, 1468 Madison Ave\, New York\, NY\, 10029\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170601
DTEND;VALUE=DATE:20170702
DTSTAMP:20260819T030932
CREATED:20170601T171644Z
LAST-MODIFIED:20170601T171929Z
UID:18249-1496275200-1498953599@ces.b2sg.org
SUMMARY:Postdoctoral Fellow
DESCRIPTION:JOB DESCRIPTION:  \nHelps design and conduct research within a specified field while receiving advanced training from a designated Principal Investigator to enhance professional skills and research independence needed for pursuit of a career. The specific area of research in which the trainee is mentored is determined by the department and laboratory of the Postdoc. Designs and evaluates experiments. Develops new ideas that promote current research. Prepares and publishes scientific manuscripts under the direction of the Principal Investigator. May be responsible for operation of specific equipment. May teach techniques to others\, train\, and supervise research staff. Positions are temporary appointments as a research trainee. The initial appointment is for one year\, renewal expected if progress is satisfactory and funds are available. Appointments cannot exceed five years. \n\nMINIMUM QUALIFICATIONS:  \nA doctoral degree or equivalent (Ph.D.\, M.D.\, ScD.\, D.V.M.\, DDS etc) in an appropriate field. Excellent scientific writing ability and strong oral communication skills. The ability to work effectively and collegially with colleagues. Additional qualifications as specified by the Principal Investigator. \n  \n\n\nRequired Qualifications:  \nA doctoral degree or equivalent (Ph.D.\, M.D.\, ScD.\, D.V.M.\, DDS etc) in. in Environmental Health\, Toxicology\, Epidemiology\, Genomics/Bioinformatics\, Statistics/Biostatistics\, or other relevant disciplines. Strong quantitative skills are necessary. Specific experiences in using the R programming environment\, and in working with genome-scale DNA methylation or other genomics data is required\, and experiences in laboratory-based molecular assessment and in the use of bioinformatic databases and platforms is desirable. In addition\, candidates should have excellent scientific writing and strong oral communications skills\, as well as the ability to work effectively\, collaboratively\, and collegially with colleagues. \n\n\n\nAdditional Job Details: \nThe Laboratory of Environmental Genomics\, in the Department of Environmental Health (www.sph.emory.edu/eh) at the Rollins School of Public Health of Emory University in Atlanta\, Georgia (PI: Carmen Marsit) invites highly qualified and motivated applicants to a Postdoctoral Fellow position in environmental epigenomics. The laboratory is currently investigating the influence of the environment on the human epigenome and the health ramification of these alterations. Projects in the lab focus on studies of children’s environmental health as well as on human cancer. \nThe postdoctoral fellow will help design and conduct research in the field of environmental genomics and epigenomics. Specifically\, the fellow will work on research projects focused on the collection\, analysis and interpretation of genome-wide epigenetic data including DNA methylation\, imprinted gene expression\, and miRNA expression\, obtained in epidemiologic investigations and/or from experimental studies. The fellow will be encouraged to develop new ideas that promote current research\, and will be required to prepare and publish scientific manuscripts under the direction of the Principal Investigator. The fellow will also be involved in the teaching and training of others\, including students and research staff. Opportunities for the associate to apply for independent funding will be available and encouraged.  \nThe laboratory is part of the Emory HERCULES Center for Exposome Research and the Winship Cancer Center at Emory\, and participates in multiple NIEHS Children’s Environmental Health Centers as well as in a number of Developmental Origins of Health and Disease (DOHaD) related projects. The resources and collaborators in these programs will also be available to the postdoctoral associate. \n  \n\n\nThis position involves: \nInvolve working with human blood\, body fluids\, tissues\, or other potentially infectious materials.
URL:https://ces.b2sg.org/event/postdoctoral-fellow-2/
LOCATION:Emory University\, 201 Dowman Dr\, Atlanta\, GA\, 30322\, United States
CATEGORIES:Jobs
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170603
DTEND;VALUE=DATE:20170704
DTSTAMP:20260819T030932
CREATED:20170603T132813Z
LAST-MODIFIED:20170603T133221Z
UID:18264-1496448000-1499126399@ces.b2sg.org
SUMMARY:Research Scientist I
DESCRIPTION:The Fan lab at the UNM Comprehensive Cancer Center (UNMCCC) is looking for an enthusiastic and self-motivated research scientist to join our research team. The successful applicant will work closely with Dr. Fan and research fellows in the lab in the ongoing research in epigenetics. This individual is expected to keep daily laboratory notes. Other responsibilities include ordering supplies\, maintaining equipment\, ensuring laboratory compliance and teaching new lab members.  \nSuccessful candidate may be required to submit to a pre-placement medical clearance through Employee Occupational Health Services depending on location and nature of position \n\nMinimum Qualifications: \nBachelor’s degree; no previous experience required.  Completed degree(s) from an accredited institution that are above the minimum education requirement may be substituted for experience on a year for year basis. \n\nPreferred Qualifications:  \n·         BS or MS in biology\, biotechnology or related field. \n·         Experience in molecular biology or biochemistry research. \n·         Able to work independently without continuous supervision \n·         Willing to help and interact with other lab members \n·         Able to interact successfully and productively with core facilities in the center. \n·         Self-motivated\, excited about research and willing to work in a fast-paced environment. \nFinalists should be prepared to provide official educational transcripts if selected for hire. Applicants must provide names of 3 past or present supervisors as references that the hiring official can contact.
URL:https://ces.b2sg.org/event/research-scientist-unm-jun2017/
LOCATION:The University of New Mexico Comprehensive Cancer Center\, 1201 Camino de Salud\, Albuquerque\, NM\, 87106\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20170603
DTEND;VALUE=DATE:20170704
DTSTAMP:20260819T030932
CREATED:20170603T134208Z
LAST-MODIFIED:20170603T135549Z
UID:18269-1496448000-1499126399@ces.b2sg.org
SUMMARY:Sr Research Assistant - Cancer Biology\, mouse handling and tissue culture
DESCRIPTION:The lab is expanding their work on the molecular underpinnings of metastasis and are beginning to translate their findings into novel therapeutic approaches. Novel areas of interest include\, but are not limited to\, the role of epigenetics and metabolism in tumor progression and metastasis. We are also focused in understanding changes in transcriptome repertoire (coding and non-coding events) and the influence of genetic and epigenetic regulators during cancer progression and metastasis. Work in the lab is done in several in vitro as well as in vivo model systems. The lab is currently focusing on modelling prostate cancer in patient derived xenografts and in organoid culture.\n \nThe salary range is min $ 38\,000 mid $ 47\,500 max $ 57\,000.\n\n\n \nKEY FUNCTIONS:\n\n1. Animal Studies:   \nPerforming animal studies including injecting tumor cells\, monitoring and recording progress of experiments\, necropsy\, preparation of tissue samples for histological processing.  Animals include “nude” and conventional mice.\n \n2. Tissue Sections: \nPreparing frozen and fixed tissue sections for histological and immunostaining analysis of mouse and human tumor xenografts. Performing double and triple immunofluorescence and immunohistochemistry staining experiments\, including optimization of new antibodies and other reagents.\n \n3. Molecular Cytology Techniques:    \nPerforming molecular cytology techniques\, such as in situ hybridization\, X-gal staining\, BrdU and EdU incorporation\, and detection of hypoxia and cellular senescence.\n \n4. Laboratory Studies:  \nPerforms laboratory studies using complex techniques including tissue culture (maintaining mammalian cells\, growth assays\, drug response assays)\, nucleic acid extraction\, RT-PCR\, immunoblotting\, immunocytochemistry and immunohistochemistry.\n \n5. Laboratory Organization and Monitoring:   \nOrders and organizes supplies for the laboratory.  Performs regular monitoring of safety standards in the laboratory\, maintains records of hazardous materials. \n\nEDUCATION: \nRequired: Bachelor’s degree in one of the natural sciences or related field. \nEXPERIENCE: \nRequired: Three years of experience in scientific or experimental research work. With preferred degree\, one year of required experience. \nPreferred: Mouse handling\, and tissue culture.
URL:https://ces.b2sg.org/event/sr-research-assistant-mdanderson/
LOCATION:MD Anderson Cancer Center\, 1515 Holcombe Blvd\, Houston\, TX\, 77030\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170603
DTEND;VALUE=DATE:20170901
DTSTAMP:20260819T030932
CREATED:20170603T184100Z
LAST-MODIFIED:20170603T184316Z
UID:18274-1496448000-1504223999@ces.b2sg.org
SUMMARY:Research Specialist I
DESCRIPTION:Job summary \nResearch Specialist: Plan\, conduct and analyze complex laboratory research in ovarian cancer biology using molecular biology\, biochemical techniques\, tissue culture systems\, and high throughput techniques. Additional responsibilities would include assisting with the management of the daily laboratory operations. Specific job duties and responsibilities would vary depending upon the course of research. Opportunities to gain experience with primary tissue culture from ovarian cancer patients and exposure to high content and high throughput screening programs. \nTo test our hypothesis that normal stromal cells are reprogrammed into cancer-associated fibroblasts through epigenetic alterations that metabolically-drive ovarian cancer metastasis. You will assist with research projects in the laboratory\, including collecting\, documenting\, analyzing and interpreting data. Tissue culture experiments involve maintaining cell lines\, primary cell isolation and culture\, transfections\, treatment regimens\, functional assays (viability\, proliferation and invasion)\, automated plating and luciferase assays. Molecular biology and biochemical techniques may include enzyme-linked immunoassays\, luciferase assays\, fluorescent assays and cloning. Assist in preparation of grant applications and manuscripts including literature searches and review. Assist in general laboratory upkeep\, including ordering of supplies and preparation of media and stock solutions.   \n  \nEducation: \nBachelor’s degree in a field relevant to the research being conducted required.   \nExperience: \nA minimum of one year of relevant research experience preferred. \nPrevious experience with tissue culture techniques\, enzyme-linked immunoassays\, high content assays\, high-performance liquid chromatography (HPLC) and/or surface plasmon resonance (SPR) is strongly preferred.   \n  \nCompetencies: \nBasic knowledge of cell biology\, molecular biology\, and biochemistry.\nProblem-solving and quantitative skills required.\nAttention to detail required.\nOrganizational skills required.\nAbility to learn new research techniques or methods required.\nAbility to work independently and as part of a team required.   \nRequired documents: \nResume\nCover Letter\nReference Contact Information  
URL:https://ces.b2sg.org/event/research-uchicago-june2017/
LOCATION:University of Chicago\, 5801 S Ellis Ave\, Chicago\, IL\, 60637\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170603
DTEND;VALUE=DATE:20170704
DTSTAMP:20260819T030932
CREATED:20170603T204211Z
LAST-MODIFIED:20170603T205508Z
UID:18280-1496448000-1499126399@ces.b2sg.org
SUMMARY:Research Assistant I
DESCRIPTION:SUMMARY\n \nThe primary purpose of the Research Assistant I position is to provide technical assistance in carrying out various research projects in the Department of Epigenetics and Molecular Carcinogenesis.\n \n \nJOB SPECIFIC COMPETENCIES\n \nResearch Support: Provide experimental and technical support for ongoing research projects. Perform duties in accordance with general and/or specific plans.  Assists in the design of laboratory experiments\, techniques\, and protocols. Processes\, organizes and summarizes data\, reporting experiment results using a variety of scientific\, word processing\, spreadsheet or statistical software applications or program platforms. Preparation of tissues\, cell cultures\, blood samples\, and perform other laboratory duties\, such as the handling of laboratory animals. Assist in general laboratory operation\, ensures the laboratory is prepared for experiments\, performs related laboratory maintenance such as maintaining and cleaning equipment and assisting with monitoring and stocking supplies\, preparation of stock solutions and other reagents. Collect and analyze data from experimental procedures and discuss results with the principal investigator. Document experimental results and maintain an organized laboratory notebook. Prepare materials for submission to granting agencies and foundations. May instruct other staff and students in basic laboratory techniques. \n \n \nExpertise and Specialization  \n \nApply basic background in science to the application of laboratory techniques\, using judgment\, analysis and evaluation. Read literature and confer with superiors regarding new procedures. Master essential skills and techniques used in the laboratory. \n \n \nLaboratory Organization   \n \nContribute to the laboratory.  Pursue learning and self-development.  Actively seek feedback.  Transfer learning into next steps.  Perform other duties as assigned.\n \n \n\n\n\nREQUIREMENTS\n \nEducation: Bachelor’s degree with major course works in one of the basic sciences.
URL:https://ces.b2sg.org/event/res-assistant-mdanderson/
LOCATION:MD Anderson Cancer Center Smithville\, 1808 Park Rd 1C\, Smithville\, TX\, 78957\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/05/MDAnderson.jpg
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20170603
DTEND;VALUE=DATE:20170704
DTSTAMP:20260819T030932
CREATED:20170603T211046Z
LAST-MODIFIED:20170603T211046Z
UID:18286-1496448000-1499126399@ces.b2sg.org
SUMMARY:Research Associate Scientist - Next Generation Sequencing
DESCRIPTION:The successful candidate will support drug discovery projects in cancer and inflammatory disease. Specifically\, he/she will work within our next generation sequencing (NGS) group and be responsible for preparing libraries for NGS studies.  \nResponsibilities: \n1. Proficiency in generating libraries for sequencing experiments\, including running protocols and quality control methods. \n2. Trouble-shoot and optimize sequencing protocols. \n3. Assist in developing new NGS protocols. \n4. Accurately maintain written reports and organize data. \n5. Review current literature pertaining to NGS technology\, oncology\, epigenetics\, and related assays.  \nSkills/Knowledge: \n1.Experience in library preparation protocols including\, but not limited to\, Illumina\, KAPA\, and Clontech. \n2. Knowledge of current NGS technology on Illumina platforms (NextSeq and HiSeq). \n3. Experience in operating and maintaining NGS equipment is a plus (Illumina preferred). \n4. Highly motivated\, organized\, capable of multitasking\, intense attention to detail\, and innovative. \n5. Excellent time management and organizational skills\, strong written and oral communication skills\, is a team player\, and is able to think creatively and solve problems. \n6. Bachelor’s degree in a scientific discipline with at least 2 years work experience.
URL:https://ces.b2sg.org/event/research-associate-scientist-next-generation-sequencing/
LOCATION:R&D Partners\, 505 Sansome St #1020\, San Francisco\, CA\, 94111\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20170605
DTEND;VALUE=DATE:20170706
DTSTAMP:20260819T030932
CREATED:20170605T062320Z
LAST-MODIFIED:20170605T062320Z
UID:18292-1496620800-1499299199@ces.b2sg.org
SUMMARY:Machine Learning Data Scientist – Algorithm Development
DESCRIPTION:At Guardant Health\, we are committed to positively and significantly impacting patient health through technology breakthroughs that address long-standing unmet needs in oncology. \nAs the leader in the field of liquid biopsy\, Guardant Health has collected cancer genomic data from over 40\,000 patients and is looking for machine learning data scientists excited about developing statistical and machine learning algorithms aimed at using this data to enable breakthroughs in cancer patient care. \n Potential applications of machine learning using liquid biopsy data include (but are not limited to): \n\nUsing epigenetic signals to detect tissue of origin\nIdentifying biomarkers predicting drug response\nPredicting the occurrence of cancer relapse\nDetecting tumor residues after surgery\nEnabling early detection of cancer in high risk patients\n\nRESPONSIBILITIES \n\nUse machine learning and signal processing techniques to develop new algorithms for NGS data analysis with impact on clinical patient care\nElucidate key dependencies and factors explaining observed mutational profiles across cancer types\nIntegrate internal and external genomic data sources for comprehensive analysis\nInteract with medial affairs and technology teams to include expert knowledge of data attributes and to design experiments generating most pertinent data for analysis\nParticipate in brainstorming sessions\, create and maintain a highly productive and motivating work environment\nProvide written documentation and specifications\n\n\nABOUT YOU \n\nPhD. in machine learning\, high dimensional statistics\, computational biology\, engineering\, mathematics\, physics or related fields\nExperienced machine learning algorithm developer with focus on genomic data applications:\n\nExperience using regression\, supervised and unsupervised learning\nExperience using deep learning applications to genomic data\nExpert knowledge of probability and statistics with focus on working with high-dimensional data\n\n\nExperienced in Python\, R\, and C/C++\nFamiliar with high-performance computing (SGE / grid\, Mesos\, MPI)\nGreat communicator with great written and verbal fluency in English\nAbility to work independently\, with minimal supervision\nDedicated to make a difference in a rapid-paced startup environment\n\nWe would like to talk with you about our exciting projects we currently have ongoing. 
URL:https://ces.b2sg.org/event/data-sci-guardant/
LOCATION:Guardant Health\, 505 Penobscot Dr.\, Redwood City\, CA\, 94063\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/05/guardant-health.jpg
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20170605
DTEND;VALUE=DATE:20170706
DTSTAMP:20260819T030932
CREATED:20170605T063315Z
LAST-MODIFIED:20170605T063450Z
UID:18295-1496620800-1499299199@ces.b2sg.org
SUMMARY:Associate Director/Director/Sr Director - Biology
DESCRIPTION:The successful candidate will serve as a group leader within a multidisciplinary drug discovery organization developing novel inhibitors targeting epigenetic enzymes implicated in cancer.  This position directly reports to the Vice-President of Biological Sciences and will play a vital role in providing leadership for the Biological Sciences Department and beyond.  The successful candidate will have a proven track record in advancing small molecule programs in cancer drug discovery (“drug-hunter” experience). Additionally\, the successful candidate will have experience in managing and mentoring scientists with diverse levels of experience and training.  Finally\, individuals with innovative and pioneering approaches to drug discovery are preferred for this role. \nResponsibilities \n  \n    Lead and manage a team of scientists\, including multiple project leaders \n    Mentor project team leaders in drug discovery and leadership matters \n    Co-lead Epizyme’s multidisciplinary efforts to validate and prioritize new targets \n  \nEducation & Requirements \n  \n    Ph.D. in a life sciences discipline (e.g. cell biology\, cancer biology\, genetics\, etc.) \n    Expertise in holistic small molecule drug discovery –“drug hunting” \n    Strong background in cancer biology/oncology drug discovery preferred \n    At least 10 years of work experience industry experience in biotech or pharma environment is required (academic experience cannot be substituted) \n    Experience in managing people is required \n    Ability to work well under pressure \n    Excellent organizational skills and attention to detail \n    Strong communications skills\, both written and oral \n    Experience in working on cross-functional teams \n    Ability to lead without authority \nEpizyme is a clinical stage biopharmaceutical company creating targeted epigenetic therapeutics for patients with cancer. Our lead program\, tazemetostat\, is in Phase 2 development for the treatment of patients with non-Hodgkin lymphoma\, and a Phase 2 adult and a Phase 1 pediatric study are planned in patients with a subset of genetically defined tumors including malignant rhabdoid tumors\, epithelioid sarcomas\, and synovial sarcomas.  Epizyme owns worldwide rights to tazemetostat outside of Japan\, and has started a broad Phase 2 clinical development program. Epizyme has built a proprietary product platform that the company uses to create small molecule inhibitors of a 96-member class of enzymes known as histone methyltransferases\, or HMTs. HMTs are part of the system of gene regulation\, referred to as epigenetics\, that controls gene expression. Genetic alterations can result in changes to the activity of HMTs\, making them oncogenic (cancer-causing). We seek a top notch contributor to join our culture of transparency\, intensity\, scientific rigor\, and fun!
URL:https://ces.b2sg.org/event/associate-directordirectorsr-director-biology/
LOCATION:Epizyme\, 400 Technology Square\, Cambridge\, MA\, 02139\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/06/epizyme.jpg
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