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PRODID:-//Cancer Epigenetics Society - ECPv5.3.2.1//NONSGML v1.0//EN
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METHOD:PUBLISH
X-WR-CALNAME:Cancer Epigenetics Society
X-ORIGINAL-URL:https://ces.b2sg.org
X-WR-CALDESC:Events for Cancer Epigenetics Society
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TZID:Europe/Paris
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TZOFFSETFROM:+0100
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TZNAME:CEST
DTSTART:20170326T010000
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TZNAME:CET
DTSTART:20171029T010000
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20170523
DTEND;VALUE=DATE:20170624
DTSTAMP:20260818T141247
CREATED:20170523T125818Z
LAST-MODIFIED:20170617T065128Z
UID:18207-1495497600-1498262399@ces.b2sg.org
SUMMARY:Bioinformatics Research Scientist
DESCRIPTION:A Bioinformatics Research Scientist position is available in the lab of Dr. Charles Mullighan\, MBBS (Hons)\, MSc\, MD. This position offers an unrivaled opportunity to be embedded in an environment leading integrated genomic and experimental studies in Leukemia. As part of our laboratory\, you will be involved in the integrative analysis of large cancer genomic datasets from patients with acute leukemia and related disorders. This involves the mapping and variant identification from large whole genome\, exome and transcriptome sequencing datasets\, and integration of such data to classify disease and predict outcome. Additional areas of work involve the analysis of epigenetic and ChIP sequencing data\, and analysis of clonal evolution in cancer. The data are derived from the largest ALL datasets from the St Jude Pediatric Cancer Genome Project\, the NCI TARGET initiative and projects initiated by Dr Mullighan.Candidates with deep understanding of cancer genomics\, genetics or epigenetics\, strong problem solving skills and expertise in next-generation sequencing data analysis are highly encouraged to apply. \n \n\n\n\nMinimum Education:\n\n\n\nPh.D. in molecular biology\, biochemistry\, computer science\, statistics\, mathematics\, bioinformatics or related field required \n \n\n\n\nMinimum Experience:\n\n\n\nPh.D which must include research related to bioinformatics (such as analysis of sequence data\, microarrays\, SNPs\, image data\, proteomics data\, or biological pathways; development of algorithms\, statistical methods\, or scientific software); OR If Ph.D with no bioinformatics research\, then two years of pre-or postdoctoral experience in computational biology or bioinformatics research is required \nExperience with programming languages such as Perl\, C\, or Java required \nExperience and knowledge on statistical analysis package such as R\, SAS and Matlab is highly desired.
URL:https://ces.b2sg.org/event/stjude-may2017/
LOCATION:St. Jude Children’s Hospital\, 262 Danny Thomas Pl\, Memphis\, TN\, 38105\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20170524
DTEND;VALUE=DATE:20170625
DTSTAMP:20260818T141247
CREATED:20170524T104050Z
LAST-MODIFIED:20170524T104050Z
UID:18211-1495584000-1498348799@ces.b2sg.org
SUMMARY:Postdoctoral Research Fellow
DESCRIPTION:The Buck Institute is the only independent institute in the U.S. devoted solely to research on aging and age-related diseases such as Alzheimer’s\, Parkinson’s\, cancer\, arthritis\, diabetes\, and stroke. Our mission is to increase the healthspan\, the healthy years of life. Awarded a federal grant to establish interdisciplinary research in a new field called Geroscience\, Buck scientists work in a unique\, collaborative environment that allows scientists to initiate studies quickly and respond to new opportunities in fields such as stem cell research and regenerative medicine. Our scientists represent a variety of complementary fields\, including genetics\, epigenetics\, biochemistry\, molecular biology\, bioenergetics\, age-associated disease; and technological disciplines such as genomics\, proteomics\, protein interaction networks and bio-informatics. \n The Buck Institute\, which was designed by world famous architect I.M. Pei\, is located in Novato\, California\, 25 miles north of the Golden Gate Bridge. \n Receive training in specific area(s) of research with the aim of progressing towards an independent career. The appointment is for one year up to a usual maximum of three to four years\, each year contingent upon satisfactory progress\, as evaluated by the supervisor/mentor. \nKey Responsibilities: \n– Receive training in specific area(s) to continue the development of personal technical knowledge and research expertise.\n – Under guidance\, design\, plan and execute original research projects or major parts thereof.\n – Develop ability to critically evaluate and analyze data.\n – Keep a careful record of experiments in laboratory notebooks.\n – Publish and present data internally and externally.\n – Assist other institute researchers in areas of personal expertise.\n – Attend and participate in institutional programs\, seminars and lectures.\n – Progress towards an independent career.\n – Encouraged to seek outside training support.\n – Provide other related duties as required \nEducation: \n      PhD in relevant field of study \nPlease complete application and submit CV to be considered for this position.
URL:https://ces.b2sg.org/event/postdoctoral-research-fellow/
LOCATION:Buck Institute\, 8001 Redwood Boulevard\, Novato\, CA\, 94945\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170524
DTEND;VALUE=DATE:20170625
DTSTAMP:20260818T141247
CREATED:20170524T111455Z
LAST-MODIFIED:20170524T112959Z
UID:18216-1495584000-1498348799@ces.b2sg.org
SUMMARY:Research Laboratory Technician Intermediate/Associate
DESCRIPTION:Seeking an experienced research associate who is energetic\, enthusiastic\, and enjoys collaborative and independent science. \nThe focus of the lab is stem cell biology and epigenetics. Since eye diseases are the first human disorders for which clinical trials for embryonic and induced pluripotent stem cell-derived tissue transplantation are being conducted\, you will be at the cutting edge of a technology important for regenerative medicine. \nThe primary job responsibility for this position is to move the research project forward through experimental work\, and coordinating work of others within the lab. Specific tasks include human and mouse stem cell\, primary\, or cancer cell culture\, immunohistochemistry\, PCR\, Western blotting\, transgenic mouse colony management\, laboratory and safety maintenance including ordering supplies. As part of their career development\, this person will learn from more experienced members of the laboratory specific assays relevant to the project. Other responsibilities based on interest and enthusiasm of the individual\, but adaptability to develop new protocols will be a requirement. \nDuties for this position include interdisciplinary interactions with Department of Pathology\, Pluripotent Stem Cell Cores\, as well as: \n\nHigh School Diploma or Associate’s Degree and 1-3 years experience required in field of biological sciences for the Intermediate level; High School Diploma or Associate’s Degree and up to 1 year experience required in field of biological sciences for the Associate level.\nHighly motivated\, detail oriented\, responsible individual with excellent communication and organizational skills who strives to work towards independence\, and is willing to teach others.\nPrevious laboratory experience (1 to 3 years) with molecular biology training (cloning\, PCR\, transfection\, transduction)\, mouse genotyping (PCR) and colony management\, western blotting\, immunohistochemistry\, protein immunoprecipitation\, viral transduction\, electroporation\, cloning.\nMust be proficient in Microsoft Office.\n\nDesired Qualifications \n\nPrevious laboratory experience with pluripotent stem cell culture (mouse and human) and use of CRISPR/Cas9 technology is required.\nPrevious laboratory experience in protein purification\, flow cytometry\, transgenic mouse colony management\, RNAi\, CRISPR/Cas9 gene editing\, RNA-seq/ChIP-seq and other genome wide assays\, bioinformatics\, and/or Python\, R language programming.\n\n\nWithin 0-10 years of terminal degree.\n\n\nBachelor’s degree in the biological sciences\, such as stem cells\, epigenetics\, bioinformatics\, cancer or a closely related field.
URL:https://ces.b2sg.org/event/research-laboratory-technician-intermediateassociate/
LOCATION:University of Michigan\, 500 S State St\, Ann Arbor\, MI\, 48109\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20170601
DTEND;VALUE=DATE:20170702
DTSTAMP:20260818T141247
CREATED:20170601T164205Z
LAST-MODIFIED:20170601T164504Z
UID:18242-1496275200-1498953599@ces.b2sg.org
SUMMARY:Associate Researcher - Oncological Sciences
DESCRIPTION:What You’ll Do:  \nHighly motivated scientists who will be working as part of a multidisciplinary team\, composed of Molecular Cancer and Computational biologists. Field of research is molecular oncology\, specifically we will dissect the role of Methyltransferases in tumor initiation and maintenance. \n \nWhat You’ll Bring:\n\nStrong background in Molecular Biology\, Epigenetic mechanisms of gene regulation\, Genomics is appreciated.\n\nMust have a positive attitude towards team work\, and be self-motivated and well organized.\n\n\nMount Sinai Health System’s multidisciplinary clinical research teams are pioneering innovative new approaches in health care across a variety of fields. Working alongside leading physicians and within internationally acclaimed medical institutes\, centers\, and laboratories\, our scientists continue to shape the future of clinical care and improve outcomes for patients of all ages.  \nAre you ready to discover the world of limitless possibilities that comes with wearing the badge? Explore more about this opportunity and how you can help us write a new chapter in our story of unrivaled patient care!
URL:https://ces.b2sg.org/event/associate-researcher-oncological-sciences/
LOCATION:Mount Sinai – Icahn School of Medicine\, 1468 Madison Ave\, New York\, NY\, 10029\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20170601
DTEND;VALUE=DATE:20170702
DTSTAMP:20260818T141247
CREATED:20170601T171644Z
LAST-MODIFIED:20170601T171929Z
UID:18249-1496275200-1498953599@ces.b2sg.org
SUMMARY:Postdoctoral Fellow
DESCRIPTION:JOB DESCRIPTION:  \nHelps design and conduct research within a specified field while receiving advanced training from a designated Principal Investigator to enhance professional skills and research independence needed for pursuit of a career. The specific area of research in which the trainee is mentored is determined by the department and laboratory of the Postdoc. Designs and evaluates experiments. Develops new ideas that promote current research. Prepares and publishes scientific manuscripts under the direction of the Principal Investigator. May be responsible for operation of specific equipment. May teach techniques to others\, train\, and supervise research staff. Positions are temporary appointments as a research trainee. The initial appointment is for one year\, renewal expected if progress is satisfactory and funds are available. Appointments cannot exceed five years. \n\nMINIMUM QUALIFICATIONS:  \nA doctoral degree or equivalent (Ph.D.\, M.D.\, ScD.\, D.V.M.\, DDS etc) in an appropriate field. Excellent scientific writing ability and strong oral communication skills. The ability to work effectively and collegially with colleagues. Additional qualifications as specified by the Principal Investigator. \n  \n\n\nRequired Qualifications:  \nA doctoral degree or equivalent (Ph.D.\, M.D.\, ScD.\, D.V.M.\, DDS etc) in. in Environmental Health\, Toxicology\, Epidemiology\, Genomics/Bioinformatics\, Statistics/Biostatistics\, or other relevant disciplines. Strong quantitative skills are necessary. Specific experiences in using the R programming environment\, and in working with genome-scale DNA methylation or other genomics data is required\, and experiences in laboratory-based molecular assessment and in the use of bioinformatic databases and platforms is desirable. In addition\, candidates should have excellent scientific writing and strong oral communications skills\, as well as the ability to work effectively\, collaboratively\, and collegially with colleagues. \n\n\n\nAdditional Job Details: \nThe Laboratory of Environmental Genomics\, in the Department of Environmental Health (www.sph.emory.edu/eh) at the Rollins School of Public Health of Emory University in Atlanta\, Georgia (PI: Carmen Marsit) invites highly qualified and motivated applicants to a Postdoctoral Fellow position in environmental epigenomics. The laboratory is currently investigating the influence of the environment on the human epigenome and the health ramification of these alterations. Projects in the lab focus on studies of children’s environmental health as well as on human cancer. \nThe postdoctoral fellow will help design and conduct research in the field of environmental genomics and epigenomics. Specifically\, the fellow will work on research projects focused on the collection\, analysis and interpretation of genome-wide epigenetic data including DNA methylation\, imprinted gene expression\, and miRNA expression\, obtained in epidemiologic investigations and/or from experimental studies. The fellow will be encouraged to develop new ideas that promote current research\, and will be required to prepare and publish scientific manuscripts under the direction of the Principal Investigator. The fellow will also be involved in the teaching and training of others\, including students and research staff. Opportunities for the associate to apply for independent funding will be available and encouraged.  \nThe laboratory is part of the Emory HERCULES Center for Exposome Research and the Winship Cancer Center at Emory\, and participates in multiple NIEHS Children’s Environmental Health Centers as well as in a number of Developmental Origins of Health and Disease (DOHaD) related projects. The resources and collaborators in these programs will also be available to the postdoctoral associate. \n  \n\n\nThis position involves: \nInvolve working with human blood\, body fluids\, tissues\, or other potentially infectious materials.
URL:https://ces.b2sg.org/event/postdoctoral-fellow-2/
LOCATION:Emory University\, 201 Dowman Dr\, Atlanta\, GA\, 30322\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20170603
DTEND;VALUE=DATE:20170704
DTSTAMP:20260818T141247
CREATED:20170603T132813Z
LAST-MODIFIED:20170603T133221Z
UID:18264-1496448000-1499126399@ces.b2sg.org
SUMMARY:Research Scientist I
DESCRIPTION:The Fan lab at the UNM Comprehensive Cancer Center (UNMCCC) is looking for an enthusiastic and self-motivated research scientist to join our research team. The successful applicant will work closely with Dr. Fan and research fellows in the lab in the ongoing research in epigenetics. This individual is expected to keep daily laboratory notes. Other responsibilities include ordering supplies\, maintaining equipment\, ensuring laboratory compliance and teaching new lab members.  \nSuccessful candidate may be required to submit to a pre-placement medical clearance through Employee Occupational Health Services depending on location and nature of position \n\nMinimum Qualifications: \nBachelor’s degree; no previous experience required.  Completed degree(s) from an accredited institution that are above the minimum education requirement may be substituted for experience on a year for year basis. \n\nPreferred Qualifications:  \n·         BS or MS in biology\, biotechnology or related field. \n·         Experience in molecular biology or biochemistry research. \n·         Able to work independently without continuous supervision \n·         Willing to help and interact with other lab members \n·         Able to interact successfully and productively with core facilities in the center. \n·         Self-motivated\, excited about research and willing to work in a fast-paced environment. \nFinalists should be prepared to provide official educational transcripts if selected for hire. Applicants must provide names of 3 past or present supervisors as references that the hiring official can contact.
URL:https://ces.b2sg.org/event/research-scientist-unm-jun2017/
LOCATION:The University of New Mexico Comprehensive Cancer Center\, 1201 Camino de Salud\, Albuquerque\, NM\, 87106\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20170603
DTEND;VALUE=DATE:20170704
DTSTAMP:20260818T141247
CREATED:20170603T134208Z
LAST-MODIFIED:20170603T135549Z
UID:18269-1496448000-1499126399@ces.b2sg.org
SUMMARY:Sr Research Assistant - Cancer Biology\, mouse handling and tissue culture
DESCRIPTION:The lab is expanding their work on the molecular underpinnings of metastasis and are beginning to translate their findings into novel therapeutic approaches. Novel areas of interest include\, but are not limited to\, the role of epigenetics and metabolism in tumor progression and metastasis. We are also focused in understanding changes in transcriptome repertoire (coding and non-coding events) and the influence of genetic and epigenetic regulators during cancer progression and metastasis. Work in the lab is done in several in vitro as well as in vivo model systems. The lab is currently focusing on modelling prostate cancer in patient derived xenografts and in organoid culture.\n \nThe salary range is min $ 38\,000 mid $ 47\,500 max $ 57\,000.\n\n\n \nKEY FUNCTIONS:\n\n1. Animal Studies:   \nPerforming animal studies including injecting tumor cells\, monitoring and recording progress of experiments\, necropsy\, preparation of tissue samples for histological processing.  Animals include “nude” and conventional mice.\n \n2. Tissue Sections: \nPreparing frozen and fixed tissue sections for histological and immunostaining analysis of mouse and human tumor xenografts. Performing double and triple immunofluorescence and immunohistochemistry staining experiments\, including optimization of new antibodies and other reagents.\n \n3. Molecular Cytology Techniques:    \nPerforming molecular cytology techniques\, such as in situ hybridization\, X-gal staining\, BrdU and EdU incorporation\, and detection of hypoxia and cellular senescence.\n \n4. Laboratory Studies:  \nPerforms laboratory studies using complex techniques including tissue culture (maintaining mammalian cells\, growth assays\, drug response assays)\, nucleic acid extraction\, RT-PCR\, immunoblotting\, immunocytochemistry and immunohistochemistry.\n \n5. Laboratory Organization and Monitoring:   \nOrders and organizes supplies for the laboratory.  Performs regular monitoring of safety standards in the laboratory\, maintains records of hazardous materials. \n\nEDUCATION: \nRequired: Bachelor’s degree in one of the natural sciences or related field. \nEXPERIENCE: \nRequired: Three years of experience in scientific or experimental research work. With preferred degree\, one year of required experience. \nPreferred: Mouse handling\, and tissue culture.
URL:https://ces.b2sg.org/event/sr-research-assistant-mdanderson/
LOCATION:MD Anderson Cancer Center\, 1515 Holcombe Blvd\, Houston\, TX\, 77030\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20170603
DTEND;VALUE=DATE:20170901
DTSTAMP:20260818T141247
CREATED:20170603T184100Z
LAST-MODIFIED:20170603T184316Z
UID:18274-1496448000-1504223999@ces.b2sg.org
SUMMARY:Research Specialist I
DESCRIPTION:Job summary \nResearch Specialist: Plan\, conduct and analyze complex laboratory research in ovarian cancer biology using molecular biology\, biochemical techniques\, tissue culture systems\, and high throughput techniques. Additional responsibilities would include assisting with the management of the daily laboratory operations. Specific job duties and responsibilities would vary depending upon the course of research. Opportunities to gain experience with primary tissue culture from ovarian cancer patients and exposure to high content and high throughput screening programs. \nTo test our hypothesis that normal stromal cells are reprogrammed into cancer-associated fibroblasts through epigenetic alterations that metabolically-drive ovarian cancer metastasis. You will assist with research projects in the laboratory\, including collecting\, documenting\, analyzing and interpreting data. Tissue culture experiments involve maintaining cell lines\, primary cell isolation and culture\, transfections\, treatment regimens\, functional assays (viability\, proliferation and invasion)\, automated plating and luciferase assays. Molecular biology and biochemical techniques may include enzyme-linked immunoassays\, luciferase assays\, fluorescent assays and cloning. Assist in preparation of grant applications and manuscripts including literature searches and review. Assist in general laboratory upkeep\, including ordering of supplies and preparation of media and stock solutions.   \n  \nEducation: \nBachelor’s degree in a field relevant to the research being conducted required.   \nExperience: \nA minimum of one year of relevant research experience preferred. \nPrevious experience with tissue culture techniques\, enzyme-linked immunoassays\, high content assays\, high-performance liquid chromatography (HPLC) and/or surface plasmon resonance (SPR) is strongly preferred.   \n  \nCompetencies: \nBasic knowledge of cell biology\, molecular biology\, and biochemistry.\nProblem-solving and quantitative skills required.\nAttention to detail required.\nOrganizational skills required.\nAbility to learn new research techniques or methods required.\nAbility to work independently and as part of a team required.   \nRequired documents: \nResume\nCover Letter\nReference Contact Information  
URL:https://ces.b2sg.org/event/research-uchicago-june2017/
LOCATION:University of Chicago\, 5801 S Ellis Ave\, Chicago\, IL\, 60637\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20170603
DTEND;VALUE=DATE:20170704
DTSTAMP:20260818T141247
CREATED:20170603T204211Z
LAST-MODIFIED:20170603T205508Z
UID:18280-1496448000-1499126399@ces.b2sg.org
SUMMARY:Research Assistant I
DESCRIPTION:SUMMARY\n \nThe primary purpose of the Research Assistant I position is to provide technical assistance in carrying out various research projects in the Department of Epigenetics and Molecular Carcinogenesis.\n \n \nJOB SPECIFIC COMPETENCIES\n \nResearch Support: Provide experimental and technical support for ongoing research projects. Perform duties in accordance with general and/or specific plans.  Assists in the design of laboratory experiments\, techniques\, and protocols. Processes\, organizes and summarizes data\, reporting experiment results using a variety of scientific\, word processing\, spreadsheet or statistical software applications or program platforms. Preparation of tissues\, cell cultures\, blood samples\, and perform other laboratory duties\, such as the handling of laboratory animals. Assist in general laboratory operation\, ensures the laboratory is prepared for experiments\, performs related laboratory maintenance such as maintaining and cleaning equipment and assisting with monitoring and stocking supplies\, preparation of stock solutions and other reagents. Collect and analyze data from experimental procedures and discuss results with the principal investigator. Document experimental results and maintain an organized laboratory notebook. Prepare materials for submission to granting agencies and foundations. May instruct other staff and students in basic laboratory techniques. \n \n \nExpertise and Specialization  \n \nApply basic background in science to the application of laboratory techniques\, using judgment\, analysis and evaluation. Read literature and confer with superiors regarding new procedures. Master essential skills and techniques used in the laboratory. \n \n \nLaboratory Organization   \n \nContribute to the laboratory.  Pursue learning and self-development.  Actively seek feedback.  Transfer learning into next steps.  Perform other duties as assigned.\n \n \n\n\n\nREQUIREMENTS\n \nEducation: Bachelor’s degree with major course works in one of the basic sciences.
URL:https://ces.b2sg.org/event/res-assistant-mdanderson/
LOCATION:MD Anderson Cancer Center Smithville\, 1808 Park Rd 1C\, Smithville\, TX\, 78957\, United States
CATEGORIES:Jobs
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DTSTART;VALUE=DATE:20170603
DTEND;VALUE=DATE:20170704
DTSTAMP:20260818T141247
CREATED:20170603T211046Z
LAST-MODIFIED:20170603T211046Z
UID:18286-1496448000-1499126399@ces.b2sg.org
SUMMARY:Research Associate Scientist - Next Generation Sequencing
DESCRIPTION:The successful candidate will support drug discovery projects in cancer and inflammatory disease. Specifically\, he/she will work within our next generation sequencing (NGS) group and be responsible for preparing libraries for NGS studies.  \nResponsibilities: \n1. Proficiency in generating libraries for sequencing experiments\, including running protocols and quality control methods. \n2. Trouble-shoot and optimize sequencing protocols. \n3. Assist in developing new NGS protocols. \n4. Accurately maintain written reports and organize data. \n5. Review current literature pertaining to NGS technology\, oncology\, epigenetics\, and related assays.  \nSkills/Knowledge: \n1.Experience in library preparation protocols including\, but not limited to\, Illumina\, KAPA\, and Clontech. \n2. Knowledge of current NGS technology on Illumina platforms (NextSeq and HiSeq). \n3. Experience in operating and maintaining NGS equipment is a plus (Illumina preferred). \n4. Highly motivated\, organized\, capable of multitasking\, intense attention to detail\, and innovative. \n5. Excellent time management and organizational skills\, strong written and oral communication skills\, is a team player\, and is able to think creatively and solve problems. \n6. Bachelor’s degree in a scientific discipline with at least 2 years work experience.
URL:https://ces.b2sg.org/event/research-associate-scientist-next-generation-sequencing/
LOCATION:R&D Partners\, 505 Sansome St #1020\, San Francisco\, CA\, 94111\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20170605
DTEND;VALUE=DATE:20170706
DTSTAMP:20260818T141247
CREATED:20170605T062320Z
LAST-MODIFIED:20170605T062320Z
UID:18292-1496620800-1499299199@ces.b2sg.org
SUMMARY:Machine Learning Data Scientist – Algorithm Development
DESCRIPTION:At Guardant Health\, we are committed to positively and significantly impacting patient health through technology breakthroughs that address long-standing unmet needs in oncology. \nAs the leader in the field of liquid biopsy\, Guardant Health has collected cancer genomic data from over 40\,000 patients and is looking for machine learning data scientists excited about developing statistical and machine learning algorithms aimed at using this data to enable breakthroughs in cancer patient care. \n Potential applications of machine learning using liquid biopsy data include (but are not limited to): \n\nUsing epigenetic signals to detect tissue of origin\nIdentifying biomarkers predicting drug response\nPredicting the occurrence of cancer relapse\nDetecting tumor residues after surgery\nEnabling early detection of cancer in high risk patients\n\nRESPONSIBILITIES \n\nUse machine learning and signal processing techniques to develop new algorithms for NGS data analysis with impact on clinical patient care\nElucidate key dependencies and factors explaining observed mutational profiles across cancer types\nIntegrate internal and external genomic data sources for comprehensive analysis\nInteract with medial affairs and technology teams to include expert knowledge of data attributes and to design experiments generating most pertinent data for analysis\nParticipate in brainstorming sessions\, create and maintain a highly productive and motivating work environment\nProvide written documentation and specifications\n\n\nABOUT YOU \n\nPhD. in machine learning\, high dimensional statistics\, computational biology\, engineering\, mathematics\, physics or related fields\nExperienced machine learning algorithm developer with focus on genomic data applications:\n\nExperience using regression\, supervised and unsupervised learning\nExperience using deep learning applications to genomic data\nExpert knowledge of probability and statistics with focus on working with high-dimensional data\n\n\nExperienced in Python\, R\, and C/C++\nFamiliar with high-performance computing (SGE / grid\, Mesos\, MPI)\nGreat communicator with great written and verbal fluency in English\nAbility to work independently\, with minimal supervision\nDedicated to make a difference in a rapid-paced startup environment\n\nWe would like to talk with you about our exciting projects we currently have ongoing. 
URL:https://ces.b2sg.org/event/data-sci-guardant/
LOCATION:Guardant Health\, 505 Penobscot Dr.\, Redwood City\, CA\, 94063\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20170605
DTEND;VALUE=DATE:20170706
DTSTAMP:20260818T141247
CREATED:20170605T063315Z
LAST-MODIFIED:20170605T063450Z
UID:18295-1496620800-1499299199@ces.b2sg.org
SUMMARY:Associate Director/Director/Sr Director - Biology
DESCRIPTION:The successful candidate will serve as a group leader within a multidisciplinary drug discovery organization developing novel inhibitors targeting epigenetic enzymes implicated in cancer.  This position directly reports to the Vice-President of Biological Sciences and will play a vital role in providing leadership for the Biological Sciences Department and beyond.  The successful candidate will have a proven track record in advancing small molecule programs in cancer drug discovery (“drug-hunter” experience). Additionally\, the successful candidate will have experience in managing and mentoring scientists with diverse levels of experience and training.  Finally\, individuals with innovative and pioneering approaches to drug discovery are preferred for this role. \nResponsibilities \n  \n    Lead and manage a team of scientists\, including multiple project leaders \n    Mentor project team leaders in drug discovery and leadership matters \n    Co-lead Epizyme’s multidisciplinary efforts to validate and prioritize new targets \n  \nEducation & Requirements \n  \n    Ph.D. in a life sciences discipline (e.g. cell biology\, cancer biology\, genetics\, etc.) \n    Expertise in holistic small molecule drug discovery –“drug hunting” \n    Strong background in cancer biology/oncology drug discovery preferred \n    At least 10 years of work experience industry experience in biotech or pharma environment is required (academic experience cannot be substituted) \n    Experience in managing people is required \n    Ability to work well under pressure \n    Excellent organizational skills and attention to detail \n    Strong communications skills\, both written and oral \n    Experience in working on cross-functional teams \n    Ability to lead without authority \nEpizyme is a clinical stage biopharmaceutical company creating targeted epigenetic therapeutics for patients with cancer. Our lead program\, tazemetostat\, is in Phase 2 development for the treatment of patients with non-Hodgkin lymphoma\, and a Phase 2 adult and a Phase 1 pediatric study are planned in patients with a subset of genetically defined tumors including malignant rhabdoid tumors\, epithelioid sarcomas\, and synovial sarcomas.  Epizyme owns worldwide rights to tazemetostat outside of Japan\, and has started a broad Phase 2 clinical development program. Epizyme has built a proprietary product platform that the company uses to create small molecule inhibitors of a 96-member class of enzymes known as histone methyltransferases\, or HMTs. HMTs are part of the system of gene regulation\, referred to as epigenetics\, that controls gene expression. Genetic alterations can result in changes to the activity of HMTs\, making them oncogenic (cancer-causing). We seek a top notch contributor to join our culture of transparency\, intensity\, scientific rigor\, and fun!
URL:https://ces.b2sg.org/event/associate-directordirectorsr-director-biology/
LOCATION:Epizyme\, 400 Technology Square\, Cambridge\, MA\, 02139\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170608
DTEND;VALUE=DATE:20170709
DTSTAMP:20260818T141247
CREATED:20170608T183512Z
LAST-MODIFIED:20170608T183707Z
UID:18301-1496880000-1499558399@ces.b2sg.org
SUMMARY:Professor - Cancer Biology
DESCRIPTION:Qualifications:   All successful candidates must possess a Ph.D. and/or M.D. degree(s) and work on basic mechanisms of cancer in areas complementing the existing strengths of the department. We invite applications from candidates with postdoctoral experience and a substantial publication record in broad areas of interest including: the tumor microenvironment\, anti-tumor immunity\, tumor metabolism\, cancer cell-intrinsic signaling pathways\, cancer epigenetics\, bioinformatics and cancer metastasis. Successful candidates appointed at the Associate or Professor level must have an outstanding track record in publications and external grant funding.  \nApplication Process:   Applicants must complete and submit an official application at https://jobs.uc.edu (Posting 13041) and must include a single document attachment including a CV\, summaries of research accomplishments and research plan (1 page each)\, and names of three references.  Interested applicants may also contact the Cancer Biology Search Committee\, c/o Cara Kramer at kramerce@ucmail.uc.edu for further information and/or details regarding the position.
URL:https://ces.b2sg.org/event/prof-uni-cincinnati/
LOCATION:University of Cincinnati\, 2600 Clifton Ave\, Cincinnati\, OH\, 45220\, United States
CATEGORIES:Jobs
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170615
DTEND;VALUE=DATE:20170717
DTSTAMP:20260818T141247
CREATED:20170210T180247Z
LAST-MODIFIED:20170615T131915Z
UID:17656-1497484800-1500249599@ces.b2sg.org
SUMMARY:Postdoctoral Associate - Breast Cancer Research
DESCRIPTION:The Braman Family Breast Cancer Institute at the University of Miami’s Sylvester Comprehensive Cancer Center has an exciting opportunity for a Postdoctoral Associate. This position carries out advanced independent and/or directed research to achieve the objectives of the research project. Duties assigned to this position involves using in-depth knowledge as well as organizing and implementing complex research plans\, developing research methods\, testing and collecting data\, analysis and evaluation. Duties also involve writing reports containing descriptive\, analytical and evaluative content. The Postdoctoral Associate will assist the Principle Investigator who is the Director of the Braman Family Breast Cancer Center and will conduct research\, ensuring that all experiments are appropriately conducted following the policies and procedures of the University of Miami.  \nThe minimum qualifications for this position: Ph.D. in a relevant field of study such as cellular and molecular biology\, immunology\, stem cell or leukemia research. Candidates must have successfully defended their thesis to be eligible for consideration. Possess broad knowledge of hematological malignancy or related fields of cancer research as well as experience in human cell/tissue culture\, molecular biological techniques\, experimental experience with animal models\, studies in epigenetics and experience in cancer research. Ability to plan\, organize and meet deadlines. Must be highly motivated. Ability to pay close attention to detail. Excellent communication skills\, both verbal and written\, with the ability to professionally interact and collaborate with others. Knowledge and experience using Microsoft Word\, Excel and PowerPoint. Ability to successfully manage multiple tasks simultaneously and independently. Ability to apply logic and demonstrate problem solving skills.
URL:https://ces.b2sg.org/event/uhealth-breast-cancer/
LOCATION:Sylvester Comprehensive Cancer Center\, 1475 N.W. 12th Avenue\, Miami\, FL\, 33136\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170615
DTEND;VALUE=DATE:20170716
DTSTAMP:20260818T141247
CREATED:20170615T123850Z
LAST-MODIFIED:20170615T123850Z
UID:18322-1497484800-1500163199@ces.b2sg.org
SUMMARY:Postdoctoral Research Associate
DESCRIPTION:The Casey Laboratory at the University of Virginia seeks a motivated Postdoctoral Research Associate in the area of cancer and stem cell research with a focus on molecular and cell biology and genomics. The candidate will join an interactive group of motivated scientists in the Center for Public Health Genomics (http://cphg.virginia.edu) at the University of Virginia to study the biology of genetic risk factors involved in colorectal cancer development.  \nOur approach integrates large amounts of genetic/genomic (for example RNA-Seq\, CRISPR-Cas9 genome editing and whole genome sequencing)\, epigenetic (for example ChIP-Seq and ATAC-Seq) and cell biology (normal human colon 3D organoid “mini-gut” models) approaches to interrogate the biological and mechanistic basis of inherited risk variants. Our goal is to understand the early changes in colon crypt stem cells leading to cancer development.  \nCandidates must have a PhD or MD degree in Molecular Biology\, Genetics\, Genomics\, or a related field in hand by start date. The successful candidate must have demonstrated expertise in at least two of the following: molecular and cell biology\, genetics\, genomics\, computational biology/bioinformatics. Experience in genomics and bioinformatics tools is highly preferred. Candidates must also have effective oral and written communication skills as demonstrated by peer reviewed publications and conference presentations\, and exhibit independence\, creativity\, and good communication skills.  \nTo apply\, visit https://jobs.virginia.edu and search on Posting Number 0621148. Complete a Candidate Profile on-line; attach a current CV\, cover letter\, and contact information for three references. The position will remain open until filled.
URL:https://ces.b2sg.org/event/uni-virginia-researcher/
LOCATION:University of Virginia\, 400 Emmet Street South\, Charlottesville\, VA\, 220903\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/06/uni-virginia.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170615
DTEND;VALUE=DATE:20170701
DTSTAMP:20260818T141247
CREATED:20170615T125845Z
LAST-MODIFIED:20170615T130049Z
UID:18329-1497484800-1498867199@ces.b2sg.org
SUMMARY:Postdoctoral Associate - Biochemistry
DESCRIPTION:The Kladde lab at the UF Health Cancer Center in the Department of Biochemistry and Molecular Biology is currently accepting applications for a Postdoctoral Associate.  The lab investigates mechanisms of epigenetic dysregulation in cancer\, focusing on establishment and maintenance of epigenetic gene silencing during cancer progression. \nDuties will include: \n\nDetermining the molecular basis of epigenetic changes during progression of breast and colon cancer in the genomes of cultured cells and patient-derived tumors.\nDevelopment of innovative\, single-molecule epigenetic assays of DNA methylation and chromatin structure; analysis of protein-DNA interactions in vitro and in vivo\, e.g.\, by chromatin immunoprecipitation (ChIP); and genome editing by CRISPR/Cas9 to test the functional relevance of regulatory sequences.\nResearching\, interpreting\, and critically evaluating primary literature; compiling and analysis of data; and maintaining a complete\, accurate\, and up-to-date lab notebook.\nPreparing and editing manuscripts for publication for dissemination of results as well as applications for grants and patents in consultation with the supervisor.\nSupervising and training of graduate students (PhD and Master’s level)\, undergraduates\, and student workers.\n\nMinimum requirements: PhD or an MD/PhD degree in the fields of biochemistry\, molecular biology\, or a related discipline. Applicants should have excellent communication and problem-solving skills and the ability to work flexible hours depending on specific experiments.  \nPreferred qualifications: Experience in protein biochemistry (e.g.\, nucleosome reconstitution and/or protein overexpression) or epigenomics (e.g.\, ChIP-seq\, RNA-seq\, bisulfite sequencing\, bioinformatics).
URL:https://ces.b2sg.org/event/postdoctoral-associate-biochemistry/
LOCATION:University of Florida\, Gainesville\, FL\, 32611\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/06/uni-florida.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170616
DTEND;VALUE=DATE:20170717
DTSTAMP:20260818T141247
CREATED:20170616T053348Z
LAST-MODIFIED:20170616T053348Z
UID:18336-1497571200-1500249599@ces.b2sg.org
SUMMARY:Postdoctoral Fellow
DESCRIPTION:Position Highlights: \n\nDr. Michael B. Mann seeks a highly motivated\, independent\, and collaborative postdoctoral research fellow interested in conducting exciting inter-disciplinary research aimed at discovering and functionally testing the genetic and epigenetic drivers of skin cancer initiation\, progression\, and therapeutic resistance.\n\n  \nThe Ideal Candidate: \n\nCan demonstrate understanding of fundamental research methodologies\, including how to plan and conduct experiments and evaluate and report research findings.\nIs experienced in molecular biology techniques\, including cloning\, PCR\, nucleic acid and protein extraction and manipulation\, culturing mammalian cell lines\, and has working knowledge of RNAi and CRISPR-Cas9 technology and viral delivery systems.\nIs experienced in building libraries for next generation sequencing platforms\nHas experience working with genetically engineered mouse models of cancer.\nHas a willingness to learn and become proficient in the use of biomedical research-oriented computer language(s) and database(s).\nIs dedicated to full-time research and professional development activities.\n\n  \nResponsibilities: \n\nLearn research techniques that directly relate to the scientific projects outlined in the lab research program with direction and supervision.\nPlan\, conduct\, and document experiments independently; evaluate and interpret data with guidance; documenting of research findings.\nDevelop scientific writing and presentation skills\, including grant proposals\, manuscript preparation\, and formal seminars presented to the Moffitt scientific community and at national scientific meetings.\nWork with an interdisciplinary core research team comprised of cancer geneticists\, computational biologists\, and biostatisticians\, and to collaborate with clinical partners to develop and test translational application(s) of research findings\n\nCredentials and Qualifications: \n\nPh.D. in Cancer Biology\, Molecular Biology\, Genetics\, or a related discipline earned within the last three years.
URL:https://ces.b2sg.org/event/postdoc-moffit-jun2017/
LOCATION:Moffitt Cancer Center Magnolia Campus\, 12902 USF Magnolia Drive\, Tampa\, FL\, 33612\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/05/Moffitt-1.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170616
DTEND;VALUE=DATE:20170717
DTSTAMP:20260818T141247
CREATED:20170616T054147Z
LAST-MODIFIED:20170616T054855Z
UID:18338-1497571200-1500249599@ces.b2sg.org
SUMMARY:Postdoctoral Fellow - Cancer & Cell Biology
DESCRIPTION:The Department of Cancer Biology at University of Cincinnati has an opening for Postdoctoral Fellow to study transcriptional and epigenetic regulation of gene expression in breast cancer. The Zhang laboratory currently focuses on elucidating molecular mechanisms of gene- and tissue- specific transcriptional cofactors in breast cancer metastasis and stem cells fate determination by using a combination of biochemical\, molecular as well as mouse genetic (conditional knockout\, mutant knockin and overexpression) approaches. We are also currently developing RNA-based nano-therapeutics to target these cofactors to overcome the endocrine and chemo- therapeutic resistance of human breast cancer. \nPosition Qualification: A Ph.D. and/or M.D. degree with research experience in biochemistry\, molecular or cellular biology. \nIdeal Qualifications: Prior experience with RNA-seq/ChIP-seq analyses\, animal studies or nanotechnology is a plus. \nInterested candidates should apply at https://jobs.uc.edu by searching position number #20028.
URL:https://ces.b2sg.org/event/postdoc2-uni-cincinnati-jun2017/
LOCATION:University of Cincinnati\, 2600 Clifton Ave\, Cincinnati\, OH\, 45220\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/06/uni-cincinnati.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170616
DTEND;VALUE=DATE:20170717
DTSTAMP:20260818T141247
CREATED:20170616T055609Z
LAST-MODIFIED:20170616T060713Z
UID:18342-1497571200-1500249599@ces.b2sg.org
SUMMARY:Postdoctoral Fellows - Stem Cell and Leukemia
DESCRIPTION:Two postdoctoral positions are available in the Stem Cell and Leukemia Program established in the laboratory of Dr. Nadia Carlesso in the Gehr Family Center for Leukemia Research at the Beckman Research Institute of City of Hope.    \nOur laboratory investigates the link between inflammation and leukemogenesis and the contribution of the bone marrow microenvironment in leukemia progression.  In particular\, we are studying the role of canonical and non-canonical Notch signaling\, NF-kB pathway and non-coding RNAs in leukemia development. Our long-term goal is to identify novel therapeutic approaches targeting simultaneously the leukemia cells and the leukemic microenvironment\, in particular in relapse. We are using in vivo models of leukemia and inflammation\, genomics\, biochemistry\, proteomics\, high throughput screening\, in vivo imaging and mathematical modeling. \nTwo positions are open to develop two independent projects: \n\nTo determine how the microenvironment and inflammation contributes to clonal dominance and transformation in models of myeloproliferative neoplasia.\nTo study the changes in cell metabolism and epigenetic regulation of hematopoietic stem cell during inflammation.\n\nTO APPLY\, e-mail a cover letter\, CV and contact information for 3 references to: Nadia Carlesso\, M.D.\, Ph.D. Professor\, Department of Hematology & Hematopoietic Cell Transplantation and Associate Director of Basic Research\, Gehr Family Center for Leukemia Research. ncarlesso@coh.org; https://www.cityofhope.org/people/carlesso-nadia \nMinimum Education and Skills Required for Consideration: \n\nThe candidate must have a doctoral degree in biomedical related fields.\nBoth positions requires skills in molecular biology\, biochemistry\, tissue culture\, multi-parameter flow cytometry\, viral vector mediated gene transfer\, mouse handling and transplantation techniques.\nThose with experience in stem cell biology\, cancer biology\, epigenetics and animal models are especially encouraged to apply.\nNewly graduated PhDs are encouraged to apply.
URL:https://ces.b2sg.org/event/postdoc-cityofhope-jun2017/
LOCATION:Beckman Research Institute\, 1500 E Duarte Rd.\, Duarte\, CA\, 91741\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170616
DTEND;VALUE=DATE:20170717
DTSTAMP:20260818T141247
CREATED:20170616T060459Z
LAST-MODIFIED:20170616T060527Z
UID:18344-1497571200-1500249599@ces.b2sg.org
SUMMARY:Postdoctoral Fellow
DESCRIPTION:Postdoctoral position: Characterizing cancer progression and metastasis \nTo develop and characterize solid cancer model systems in order to study epigenetic changes contributing to cancer progression and metastasis. These models will aid in the discovery of promising targets and evaluation of treatment strategies. The overall goal of these pre-clinical studies will be to provide supporting data for the potential clinical translation of novel\, effective therapeutic approaches.     \nPlease include CV with publication record and (if applicable) previous/current grant funding. \nMinimum Education and Skills Required for Consideration: \n\nPh.D. with emphasis in oncology and/or epigenetics\, but will also consider biochemistry\, immunology or microbiology background with experience in cancer or epigenetics research.\nExperience in flow cytometry is preferred\nMouse handling with proficiency in different routes of injection.\nStrong critical thinking skills and ability to troubleshoot.\nStrong command of the English language with the capacity to write and speak scientifically.\nShould be self-motivated\, productive\, and require little to no supervision once trained.
URL:https://ces.b2sg.org/event/postdoc2-cityofhope-jun2017/
LOCATION:Beckman Research Institute\, 1500 E Duarte Rd.\, Duarte\, CA\, 91741\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/png:https://ces.b2sg.org/wp-content/uploads/2017/02/City-of-hope.png
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170616
DTEND;VALUE=DATE:20170717
DTSTAMP:20260818T141247
CREATED:20170616T062758Z
LAST-MODIFIED:20170616T063144Z
UID:18347-1497571200-1500249599@ces.b2sg.org
SUMMARY:Postdoctoral Fellow - Functional Cancer Genomics
DESCRIPTION:Postdoctoral positions are immediately available in the laboratory of Dr. Jian Xu\, in the Children’s Research Institute of UT Southwestern Medical Center to study the functional genomics of stem cells and cancer.  The laboratory focuses on the intersection of transcriptional control with stem cell biology\, hematopoiesis and cancer. We employ epigenetics\, functional genomics\, genome editing\, biochemistry\, and mouse genetics to define epigenetic and genetic programs that control blood stem cell development\, and how these processes go awry in cancer progression. The laboratory is equipped with cutting-edge genomics and bioinformatics platforms\, and has access to numerous shared facilities including next-gen sequencing\, metabolomics\, imaging\, and flow cytometry. \nThe successful candidate must hold a Ph.D. and/or M.D. degree with a strong background in molecular biology\, mouse genetics\, genomics or a related field. The ideal candidate will exhibit independence\, flexibility and creativity with a record of scientific productivity. Previous experience in epigenetics\, generating and analyzing mouse models\, cancer genomics\, and/or hematology-oncology is strongly preferred. \nTo apply: please submit CV\, a short summary of research interest and experience\, and a list of three references to: \nJian Xu\, PhD \nAssistant Professor\, Children’s Research Institute \nCPRIT Scholar in Cancer Research \nAmerican Society of Hematology Scholar \nUT Southwestern Medical Center \n5323 Harry Hines Blvd. Dallas\, TX 75390-8502
URL:https://ces.b2sg.org/event/postdoc-utsouthwestern/
LOCATION:UT Southwestern Medical Center\, 5323 Harry Hines Blvd.\, Dallas\, TX\, 75390\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170616
DTEND;VALUE=DATE:20170717
DTSTAMP:20260818T141247
CREATED:20170616T064520Z
LAST-MODIFIED:20170616T064520Z
UID:18353-1497571200-1500249599@ces.b2sg.org
SUMMARY:Postdoctoral Fellow- Oncology
DESCRIPTION:To be considered for this position\, you must apply at www.pfizercareers.com and search for Job ID 1053047 \nWe seek a driven and accomplished postdoctoral fellow to join the cancer epigenetics group within the Oncology R&D (ORD) unit of Pfizer’s Worldwide R&D (WRD) division in La Jolla\, California. The successful candidate will collaborate with our cancer-immunopharmacology group to study the roles of epigenetic enzymes in anti-tumor immune responses. Guided by experienced mentors with strong academic track records\, the successful candidate will study fundamental questions in cancer immunology with the ultimate goal of publication in major scientific journals. Thus\, a strong scientific background with relevant expertise and documented accomplishments including significant publications is required. In addition\, the successful candidate will have a strong interest in translating results into novel immunotherapies for cancer. He/she will be highly self-motivated with a sense of urgency and focus on important problems. While driven to make strong individual contributions\, the successful candidate will also enjoy a highly interactive\, team-oriented environment and thrive by taking advantage of the significant multi-disciplinary resources available at Pfizer. This will be facilitated by the candidate’s excellent communication and interpersonal skills\, which complement strong work ethics and overall scientific excellence. \n\nResponsibilities\n\n\nPrimary Duties: \n• Work independently and as part of teams to conceive\, design\, execute\, analyze/interpret\, and refine experiments ranging from biochemical and molecular assays\, in vitro and in vivo immunological functional assays in model systems\, and clinical sample analysis.  \nSpecific duties to include:  \n• Contribute intellectually and at the bench to the conception\, design\, execution\, analysis\, interpretation and internal or external presentation of studies of epigenetic modulators of the anti-tumor immune response.  \n• Keep abreast with the literature and internal developments to become an expert point of contact for colleagues in the field of epigenetic immunopharmacology   \n• Independently\, but with guidance by experienced mentors\, develop results into compelling stories for publication in major scientific journals and presentations on major scientific meetings and conferences\, both internally and externally  \n• Apply genetic and pharmacologic approaches to modulate targets in vitro and in vivo to assess functional impacts on tumor cells and immune cells\, and on anti-tumor immune responses in syngeneic xenograft models and genetically engineered mutant mouse models of cancer. This will include CRISPR\, RNAi\, viral vector delivery\, transfection\, antibodies\, small molecules and other pharmacologic approaches to modulate targets.  \n• Execute secondary assays across various technology platforms – qRT-PCR\, immunoprecipitation\, ChIP-seq\, ATAC-seq\, FACS\, immunofluorescence\, western blotting\, ELISA\, high content screening\, etc. \n• Develop and apply complex in vitro assays for exploring target biology in tumor cells versus immune cells including T-cell functional assays\, co-culture assays\, ect.  \n• Collaborate with computational biology groups to analyze data including ChIP-seq\, RNA-seq\, ATAC-seq to support mechanism of action studies.  \n• Employ computational and proteomic methods for tumor neoantigen prediction and functional validation  \n• Use electronic data capture/analysis tools such as Excel\, GraphPad\, Biobook\, Spotfire and PowerPoint for experimental documentation and data analysis/presentations.  \n• Present research results and methodologies at weekly meetings with immediate supervisor and/or project leader\, and at meetings with members of the oncology research unit as appropriate.  \n• Contribute to building a culture that embraces scientific excellence\, urgency\, partnerships with key stakeholders\, continuous learning and improvement\, increasing technical skill base and cancer biology expertise; take a proactive role in personal growth and scientific development. \n\n\nQualifications\n\n\nEducation and Experience: \n• Ph.D. in Cell Biology\, Molecular Biology\, or Immunology  (or a comparable biological science) with a track record of scientific accomplishment as exemplified by significant scientific publications  \n• Experience with devising and implementing in vitro and in vivo immunological functional assays  \n• Experience in immuno-oncology and/or chromatin biology/epigenetics is desirable  \n• Experience in nucleic acid and protein extraction techniques and downstream analyses including quantitative RT-PCR\, immunoprecipitation (including ChIP)\, and immunoblotting.  \n• Experience with computational tools for antigen prediction\, NGS experiment design and data analyses\, including epigenomic data\, is desired  \n• Ability to work in a team environment; excellent written and oral communication skills in English; strong presentation skills and ability to discuss data at project team meetings.  \n• Able to master new concepts and techniques quickly.  \n• Strong attention to detail and organizational skills to manage projects in parallel
URL:https://ces.b2sg.org/event/postdoc-pfizer-jun2017/
LOCATION:Pfizer – Pearl River\, NY\, 401 North Middletown Road\, Pearl River\, NY\, 10965\, United States
CATEGORIES:Jobs
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170616
DTEND;VALUE=DATE:20170717
DTSTAMP:20260818T141247
CREATED:20170616T092547Z
LAST-MODIFIED:20170616T093102Z
UID:18355-1497571200-1500249599@ces.b2sg.org
SUMMARY:Assistant Research Professor
DESCRIPTION:Position Summary and Key Responsibilities \nDevelops an independent\, NIH-funded research program in the field of hematological malignancies\, serves as director of the Division of Epigenetic and Transcriptional Engineering\, leads a group of postdoctoral scientists\, provides mentorship and scientific guidance\, oversees experimental studies in his/her laboratory\, publishes high-quality research manuscripts\, develops research grant proposals for consideration by NIH and other peer-reviewed funding agencies. Performs original research in the Department of Systems Biology. Also performs all technical aspects of the Department of Systems Biology.  Evaluates and introduces new materials\, methods and equipment to help determine the feasibility and or adaptability for the Department of Systems Biology.  Assists the Department Chair in development of new technologies\, participation in quality control\, quality assurance and quality improvement procedures.  Assists Technical Associates in technical aspects of the laboratory.  \n\n\n\nThe following are essential job accountabilities:\n\n\n1. \n  \n  \n  \n  \n  \n  \n  \n  \n  \n  \n  \n  \n  \n \n\nResearch:  Oncogenic signal transduction.  Perform original research including\, but not limited to\, the role of kinases\, phosphatases\, transcription factors in regulating oncogenic cell signaling and metabolism.  \n\nRead and analyze the relevant literature.\nDevelop cutting-edge methodologies in gene editing\, transcriptional regulation (inducible dCas9 regulators)\, computational biology tools.\nContribute new ideas\, actively engage in scientific discussion\, provide expertise to inform  discussion of new concepts\nContribute to lab meetings and research Clubs\nContributing to a positive lab environment including the spirit of collaboration and helping others\nSupervision of post-doctoral fellows and technologists as relevant for research activities.\nDevelop and maintain world expertise in a suite of genes studied by the Systems Biology\nWrite original scientific manuscripts.\nReview scientific manuscripts and grant applications\n\n\nContribute and assist in grant applications.\n\n\nPathway to scientific independence: Develop concepts for own grant application with support from Department Chair.\nContribute to quality controls\, verification of scientific results\, rigor and robustness of scientific data by mentoring junior members of the Department.\nContribute to good record keeping\, archiving of primary research data\, assist with implementation of digital laboratory note books that can be shared among all members of the group\, contribute to building and maintenance of a shared file server structure.\nAct as role model and contribute to good experimental practice\, SOPs\, laboratory safety and animal welfare.\nParticipate in teaching activities of the Department and the Graduate School.\nAttend scientific conferences and present work of the group.\nDevelops an independent\, NIH-funded research program in the field of hematological malignancies.
URL:https://ces.b2sg.org/event/assistant-research-professor/
LOCATION:Beckman Research Institute\, 1500 E Duarte Rd.\, Duarte\, CA\, 91741\, United States
CATEGORIES:Jobs
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