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PRODID:-//Cancer Epigenetics Society - ECPv5.3.2.1//NONSGML v1.0//EN
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METHOD:PUBLISH
X-WR-CALNAME:Cancer Epigenetics Society
X-ORIGINAL-URL:https://ces.b2sg.org
X-WR-CALDESC:Events for Cancer Epigenetics Society
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DTSTART:20170326T010000
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TZNAME:CET
DTSTART:20171029T010000
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TZNAME:CEST
DTSTART:20180325T010000
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DTSTART:20181028T010000
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20171021
DTEND;VALUE=DATE:20180201
DTSTAMP:20260818T052704
CREATED:20171021T145301Z
LAST-MODIFIED:20171021T150555Z
UID:19256-1508544000-1517443199@ces.b2sg.org
SUMMARY:Associate/Full Professor - Pharmacology
DESCRIPTION:Candidates are expected to have a demonstrated record of excellence in research supported \nby NIH grants. \nThe individual will complement departmental programs in one or more of these areas: \n1) stem cell and regenerative biology \n2) epigenetics and transcriptional regulation; \n3) single cell transcriptomics and computational biology; \n4) optogenetic tools to dissect cell signaling;  \n5) cancer immunology; \n6) metabolomics and \n7) acute and chronic inflammation.  \nA highly competitive package is available.  The department has strong research programs \n(http://mcph.uic.edu/home) consistently ranking among the top 10 in NIH funding.  \nCandidates should have current NIH funding and have demonstrated leadership in the field. \nAll candidates are required to have a PhD\, MD or equivalent doctoral degree\, as well as an  \noutstanding publication record of the above mentioned departmental program areas.
URL:https://ces.b2sg.org/event/uic-prof-pharma/
LOCATION:University of Chicago\, 5801 S Ellis Ave\, Chicago\, IL\, 60637\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/06/University-of-Illinois-College-of-Medicine-at-Chicago-UIC-1.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20171222
DTEND;VALUE=DATE:20180124
DTSTAMP:20260818T052704
CREATED:20171222T202938Z
LAST-MODIFIED:20171222T202938Z
UID:19506-1513900800-1516751999@ces.b2sg.org
SUMMARY:Research Associate
DESCRIPTION:A position is available for a Research Associate in the laboratory of Dr. Katherine Chiappinelli\, Ph. D. at the George Washington Cancer Center (https://smhs.gwu.edu/cancercenter/) and the Department of Microbiology\, Immunology\, & Tropical Medicine (https://smhs.gwu.edu/microbiology/) at George Washington University in Washington\, DC. \nDr. Chiappinelli’s laboratory focuses on the epigenetic control of gene expression in cancer\, specifically of immune signaling in and from tumor cells. Our goal is to use epigenetic therapies to harness the power of the immune system to fight cancer. This position will aid the PI in the planning\, execution and analysis of experiments designed to elucidate epigenetic control of the interferon response in cancer. \nThe incumbent will be responsible for the daily management of the lab’s activities\, ordering reagents and personnel. These responsibilities include designing and performing experiments and assays\, data analysis and organization\, and the generation of Standard Operating Procedures (SOPs). He/she should be a clear communicator and organized thinker who is willing to collaborate with the head of the laboratory to develop and execute a diverse research program. \nDuties include:\n•Perform the following assays with optimization and troubleshooting if necessary:\n–PCR\, basic molecular cloning techniques\, and quantitative RT-PCR\n-Western blots\n-In vitro studies\, including cell culture of human cancer cell lines and shRNA or CRISPR/Cas9 manipulation of specific genes \n-Assays to analyze DNA methylation\, including pyrosequencing\n-Assays to analyze chromatin structure\, including chromatin immunoprecipitation\n•Maintain laboratory inventory\n•Manage ordering of supplies\n•Manage equipment maintenance\n•Development of organizational system to keep track of experimental data generated by all laboratory personnel\n•Performs other duties as assigned. The omission of specific duties does not preclude the supervisor from assigning duties that are logically related to the position. \nIncumbent is expected to have an enthusiasm for the practice of science and a passionate interest in the field of cancer epigenetics and/or immunology.
URL:https://ces.b2sg.org/event/gwu-22dec17/
LOCATION:George Washington University\, 2121 I St NW\, Washington\, DC\, 20052\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/05/gwu-1.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20171222
DTEND;VALUE=DATE:20180124
DTSTAMP:20260818T052704
CREATED:20171222T203715Z
LAST-MODIFIED:20171222T203855Z
UID:19508-1513900800-1516751999@ces.b2sg.org
SUMMARY:Staff Scientist
DESCRIPTION:Dr. Roberts’ lab studies the epigenetic regulation of gene expression. In particular we are studying chromatin-modifying proteins with a major focus on the SWI/SNF (BAF) chromatin remodeling/tumor suppressor complex and its relationship to cancers. Recent studies have revealed that genes encoding subunits of the SWI/SNF complex are mutated in over 20% of all cancers\, a rate approaching that of p53\, making this the most frequently mutated chromatin regulator in human malignancies. Research in the Roberts laboratory is designed to discover the mechanism by which SWI/SNF complex contributes to the regulation of gene expression and lineage specification\, and the mechanisms by which mutation of the tumor suppressor subunits drives cancer formation.  We also seek to identify specific vulnerabilities that are conferred by SWI/SNF mutation with the goal of identifying novel therapeutic opportunities. \nWe seek an ambitious scientist with a strong background in molecular biology\, cell biology\, cancer biology\, and/or genetics/epigenetics of tumorigenesis. Currently there are several projects ongoing in the laboratory involving the use of a variety of model systems that have been engineered in the lab including preclinical models\, primary cells\, and cell lines as well as the use of large sequencing\, CRISPR\, and drug vulnerability data sets. \n\nCandidates should have published in peer-reviewed journals. A prerequisite is experience in basic methods of molecular biology and biochemistry. \n\n\n\nMinimum Experience\n\n\n\n\nA minimum of five (5) years of relevant and productive postdoctoral research associate experience is required\n\n\n\n\nMinimum Education\n\n\n\n\nA Ph.D. in an appropriate scientific field is required
URL:https://ces.b2sg.org/event/stjude-22dec17/
LOCATION:St. Jude Children’s Hospital\, 262 Danny Thomas Pl\, Memphis\, TN\, 38105\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/05/stjude.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20171223
DTEND;VALUE=DATE:20180125
DTSTAMP:20260818T052704
CREATED:20171223T124541Z
LAST-MODIFIED:20171223T124741Z
UID:19515-1513987200-1516838399@ces.b2sg.org
SUMMARY:Research Assistant
DESCRIPTION:MITM is searching for a full-time Research Assistant for Dr.Chiappinelli’s laboratory at the George Washington Cancer Center (https://smhs.gwu.edu/cancercenter/) and the Department of Microbiology\, Immunology\, & Tropical Medicine. Dr. Chiappinelli’s laboratory focuses on the epigenetic control of gene expression in cancer\, specifically of immune signaling in and from tumor cells. Our goal is to use epigenetic therapies to harness the power of the immune system to fight cancer. \nThe Research Assistant will be responsible for performing experiments under the direction of the principal investigator in a biomedical research laboratory and contributing to general maintenance of the laboratory\, equipment and supplies. The individual will conduct experiments under the direct supervision of a postdoctoral fellow and will also receive mentoring and direct guidance from Dr. Chiappinelli in order to advance his/her career in academic research. \nResponsibilities include: \n•Provide assistance to research scientist\, postdoctoral scientists and lab manager\n•Optimize\, develop\, qualify and execute the following assays: basic tissue culture\, PCR\, quantitative RT-PCR\, western blots\, and flow cytometry.\n•General maintenance of the laboratory. Maintain Good Laboratory Practice\, comply with biosafety guidelines\, keep inspection records and generate SOPs and reports.\n•Maintain and troubleshoot equipment\n•Work closely with graduate students\n•Participate in group meetings and present data \n•Other duties as assigned. The omission of specific duties does not preclude the supervisor from assigning duties that are logically related to the position. \nIncumbent is expected to work well as part of a team and have enthusiasm for the practice of science.
URL:https://ces.b2sg.org/event/gwu-23dec17/
LOCATION:George Washington University\, 2121 I St NW\, Washington\, DC\, 20052\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20171223
DTEND;VALUE=DATE:20180125
DTSTAMP:20260818T052704
CREATED:20171223T131419Z
LAST-MODIFIED:20171223T131419Z
UID:19520-1513987200-1516838399@ces.b2sg.org
SUMMARY:Associate Scientist - Biomarker Development Lab
DESCRIPTION:An Associate Scientist position is available in the Pathology Biomarker Development laboratory in the Department of Pathology. This lab studies molecular biomarkers of diagnostic\, prognostic and therapeutic significance for diseases affecting St. Jude patients. We evaluate the feasibility and clinical utility of novel assays in order to determine whether they may be integrated into clinical diagnostic practice.  \n\nCurrently\, our lab is working on utilizing Illumina methylation arrays as a diagnostic tool\, exploring the utility of cell free DNA to monitor response to therapy and investigating the use of protein microarrays to identify disease biomarkers and therapeutic targets.  \n\nPrevious experience with research techniques including genomic analysis\, NGS\, methylation profiling and protein analysis are all strongly preferred. Strong skills in novel assay development and validation are preferred. Candidates with experience in cancer genomics\, genetics or epigenetics and strong problem solving skills are highly encouraged to apply. \n \n\n\n\nMinimum Experience\n\n\n\n\nA minimum of fifteen (15) years of relevant post-degree work experience is required with a Bachelor’s degree\, with at least seven (7) years at the Research Lab Specialist level\nA minimum of fourteen (14) years of relevant post-degree work experience is required with a Master’s degree\, with at least seven (7) years at the Research Lab Specialist level\nA minimum of nine (9) years of relevant work experience including post-doctoral and/or technical staff experience is required with Ph.D.
URL:https://ces.b2sg.org/event/stjude-23dec17-2/
LOCATION:St. Jude Children’s Hospital\, 262 Danny Thomas Pl\, Memphis\, TN\, 38105\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/05/stjude.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20171223
DTEND;VALUE=DATE:20180125
DTSTAMP:20260818T052704
CREATED:20171223T135303Z
LAST-MODIFIED:20171223T135516Z
UID:19522-1513987200-1516838399@ces.b2sg.org
SUMMARY:DATA SCIENTIST
DESCRIPTION:DATA SCIENTIST \nComputer Science and Software Engineering \nGRAIL is a life sciences company whose mission is to detect cancer early when it can be cured. GRAIL is using the power of high-intensity sequencing\, population-scale clinical trials\, and state of the art Computer Science and Data Science to enhance the scientific understanding of cancer biology and develop blood tests for early-stage cancer detection.  We are seeking passionate and talented individuals to join us in realizing our mission\, which has the potential to dramatically reduce the global burden of cancer. \nPOSITION SUMMARY \nOur data science team is responsible for cleaning\, preparing\, and analyzing ever increasing data sets to identify patterns to enable to early detection of cancer. We deeply understand our data and use those insights to build better methods\, pipelines\, and assays. As a data scientist\, you will build models based on some of the largest\, richest biological datasets in the world. Your rigorous analysis will guide our assay and bioinformatic pipeline development. Working closely with scientists\, clinicians\, and engineers\, you will develop new ways to pull signals out of ultra-deep sequencing data and identify cancer at its earliest stages. \nTASKS AND RESPONSIBILITIES  \n\nWork with large\, complex data sets. Solve difficult\, non-routine analysis problems\, applying advanced analytical methods as needed. Conduct end-to-end analysis that include design\, data gathering\, processing\, analysis\, iteration with stakeholders\, and dissemination of results.\nBuild and prototype analysis pipelines iteratively to provide insights at scale. Develop comprehensive understanding of relevant biology\, assays\, data structures\, and available features.\nInteract cross-functionally with a wide variety of people and teams including research\, software\, clinical\, research\, and product development.\n\nMINIMUM QUALIFICATIONS \n\n2+ years of relevant work experience in data analysis or related field. (e.g.\, as a statistician / data scientist / computational biologist / bioinformatician).\n\nPREFERRED BACKGROUND \n\nPhD degree in a quantitative discipline (e.g.\, statistics\, computational biology\, computer science\, mathematics\, physics\, electrical engineering).\n4+ years of relevant work experience in data analysis or related field. (e.g.\, as a statistician / data scientist / computational biologist) including deep expertise in stochastic modeling\, high-dimensional classification\, and/or unsupervised learning methods.\n\n\nExperience with next generation sequencing data analysis (DNA\, RNA\, or epigenetic analysis).\nDeep experience with a statistical programming language (e.g.\, R).\n\n\nDemonstrated expertise in one programming language (Python\, Go\, C++\, etc.)\, proficiency in Linux environment\, experience with database languages (e.g.\, SQL)\, experience with version control practices and tools (Git\, Perforce\, etc.).\nDemonstrated experience with and track record of implementing reproducible research practices.\n\n\nApplied experience with machine learning on large datasets.\nDemonstrated effective written and verbal communication skills.\nDemonstrated leadership and self-direction. Demonstrated willingness to both teach others and learn new techniques.
URL:https://ces.b2sg.org/event/grail-23dec17/
LOCATION:GRAIL\, Menlo Park\, CA\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/12/grail.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20171224
DTEND;VALUE=DATE:20180126
DTSTAMP:20260818T052704
CREATED:20171224T103203Z
LAST-MODIFIED:20171224T103600Z
UID:19527-1514073600-1516924799@ces.b2sg.org
SUMMARY:Research Specialist
DESCRIPTION:A Research Specialist position (mid-range) is available for a motivated\, enthusiastic and organized candidate to help with work on studying mechanisms regulating T cell development and differentiation as well as characterizing their role in tumor immunity. \nThe chosen candidate will develop and work independently on a research project as directed by the principal investigator in close collaboration with laboratory members and colleagues. The candidate will gain valuable experience in many cutting edge experimental techniques including: flow cytometric analysis\, real time PCR\, metabolism\, cell signaling/transcription/epigenetics\, functional studies of immune regulation\, murine models of cancer and human immunological evaluation. The chosen candidate will also participate in the authorship of the research publications from the lab as well as assist in the preparation and presentation of research results for dissemination. Aside from bench-work\, the candidate will also be responsible for ordering and tracking supplies for the laboratory and managing key laboratory resources including mouse colony.
URL:https://ces.b2sg.org/event/uaz-24dec17/
LOCATION:University of Arizona\, Tuscon\, AZ\, 85721\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20171224
DTEND;VALUE=DATE:20180126
DTSTAMP:20260818T052704
CREATED:20171224T104352Z
LAST-MODIFIED:20171224T104352Z
UID:19529-1514073600-1516924799@ces.b2sg.org
SUMMARY:Postdoctoral Research Associate I
DESCRIPTION:This is an exciting opportunity to take on a newly funded project to investigate T cell responses in cutaneous squamous cell carcinoma\, using mouse models and patient samples\, in the laboratory of Dr. Karen Taraszka Hastings at the University of Arizona College of Medicine – Phoenix. Other ongoing projects in our laboratory include studies of the role of gamma-interferon-inducible lysosomal thiol reductase (GILT) in antigen presentation\, T cell development\, melanoma outcome\, autoimmunity\, and redox status. Opportunities for professional development include presentation of research findings at national meetings\, mentorship in grant and manuscript writing\, teaching\, and public policy\, which will enhance career progression. \nFor further information\, please visit http://phoenixmed.arizona.edu/directory/hastings-karen and http://hastings.lab.arizona.edu/ \nDuties and responsibilities:   \n\nDesign and perform experiments\, interpret data\, and analyze results independently under the direction of the principal investigator.\n\n\nPresent research findings at internal\, local and national scientific meetings.\n\n\nPrepare manuscripts for publication in peer-reviewed journals.\n\n\nGrant writing\, including generating preliminary data\, submitting grant applications\, and preparing progress reports.\n\n\nAssist in training and supervision of technical staff and/or students.\n\n\nAssume progressively more autonomous responsibilities for project development and execution with the aim of career maturation towards becoming an independent scientist. Additional career development opportunities will be tailored to individual’s goals.\n\n\nThere may be additional duties assigned as it relates to this position.
URL:https://ces.b2sg.org/event/uaz-24dec17-2/
LOCATION:University of Arizona\, Tuscon\, AZ\, 85721\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20171226
DTEND;VALUE=DATE:20180128
DTSTAMP:20260818T052704
CREATED:20171226T144329Z
LAST-MODIFIED:20171226T144534Z
UID:19533-1514246400-1517097599@ces.b2sg.org
SUMMARY:Postdoctoral Fellow
DESCRIPTION:A postdoctoral position is immediately available in epigenetic regulation of neural stem cell differentiation. \nWe are interested in studying cell cycle or cell fate-dependent regulation of chromatin remodeling along with coordinated transcriptional regulation. We focus on an aberration in neural differentiation during aging and tumorigenesis. \nWe are looking for a motivated candidate with strong work ethics. Candidates are expected to have a PhD in above mentioned or related areas. Please send a cover letter and CV stating your research interest and career goal to Dr. Ji Paik
URL:https://ces.b2sg.org/event/wcm-26dec17/
LOCATION:Weill Cornell Medicine\, New York\, NY\, 10021\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/12/weill-cornell.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20171226
DTEND;VALUE=DATE:20180128
DTSTAMP:20260818T052704
CREATED:20171226T145415Z
LAST-MODIFIED:20171226T145542Z
UID:19537-1514246400-1517097599@ces.b2sg.org
SUMMARY:Postdoctoral Fellow
DESCRIPTION:Positions of two postdoctoral scientists are open now in the Chen laboratory (https://www.cityofhope.org/faculty/jianjun-chen). Our group is interested in discovering novel genetic and epigenetic regulations and deciphering their underlying molecular mechanisms in normal developmental processes (e.g.\, hematopoiesis) and tumorigenesis (e.g.\, leukemogenesis). We cover research areas with relevance to Hematology\, Immunology\, and Cancer Biology\, with an emphasis on RNA epigenetics (mainly focusing on the N 6 methyladenosine (m6A) modification) and DNA epigenetics (mainly focusing on the TET1/2/3-mediated DNA demethylation) associated basic and translational research. Our research involves experiments with primary human cancer cells\, cancer and stem cell transplantation models\, mouse genetics\, classic molecular\, biochemistry and cell biology\, functional genomics\, signal transduction\, and large-scale data analysis and computational biology. \nMinimum Education and Skills Required for Consideration: \nThe candidates for the Postdoctoral scientist positions should have a Ph.D. and/or M.D. degree(s)\, and a solid background in biochemistry\, mouse model studies\, hematology\, epigenetics\, immunology\, pathology\, and/or stem cell research is preferred for. The candidates should not have more than three years of postdoc training experience. The candidates should be highly motivated individuals with the ability to work in a team environment and with good oral and written communication skills in English. \nApplication: \nPlease apply to this job posting.  Additionally\, your application\, including CV\, brief motivation statement\, and contact information of three scientific mentors (references)\, should be saved as a single PDF. The PDF file can be sent to Dr. Jianjun Chen (jianchen@coh.org) directly.
URL:https://ces.b2sg.org/event/coh-26dec17/
LOCATION:City of Hope\, 1500 East Duarte Road\, Duarte\, 91010\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20171226
DTEND;VALUE=DATE:20180128
DTSTAMP:20260818T052704
CREATED:20171226T150523Z
LAST-MODIFIED:20171226T150712Z
UID:19539-1514246400-1517097599@ces.b2sg.org
SUMMARY:Senior Scientist III/ Principal Research Scientist - Translational Oncology
DESCRIPTION:The key responsibilities will be: \n\nLead development and implementation of translational medicine strategies for Oncology compounds \nApply multiple genomic and biochemical technology platforms to demonstrate target engagement\, develop and implement patient selection and diagnostic strategies.\nPartner with clinical and discovery groups to create high quality biomarker strategies in the clinic\nImplement potential novel bioanalytical platforms and introduce new ways to incorporate biomarkers into clinical program designs.\nDesign and perform experiments to elucidate resistance mechanisms that can be developed into biomarkers and new therapeutics. \nAuthor the translational research and CDx portions in key clinical documents including protocol/informed consent\, Clinical study Report\, Investigators Brochure\, etc.  Contribute the scientific and technical sections as it relates to translational science and CDx in key regulatory documents including INDs\, FDA briefing books\, and submission documents (including NDAs\, IDEs & PMAs). \nProvide hands-on clinical trial support\, including sample management\, lab work\, and report generation. \nFunction as an internal expert in oncology biomarkers and precision medicine and actively educate other team members through knowledge sharing.\nPresent and report data in external meetings and publications.\n\nLevel commensurate with experience. \nQualifications: \n\nB.S\, M.S. and/or Ph.D. in Cancer Biology\, Cell Biology\, Molecular Biology or related field with 6-8+ (Ph.D)\, 12-14+ (M.S)\, or 14-16+ (B.S) years of experience in developing and implementing  translational medicine strategies\, and a track record of success in the pharma industry.\nStrong scientific background in tumor biology and expertise in immuno-oncology\, epigenetics\, or tumor immune microenvironment is preferred.\nDemonstrated technical excellence and expertise in Translational medicine; including hands-on experience taking small molecules and/or biologics through preclinical to clinical development.\nCompanion diagnostics development experience is a plus\nExperience in analysis of large datasets and knowledge of biostatistics\nExperience in the development and utilization of biomarkers\, various technologies/platforms ( –omics technologies\, immunohistochemistry and  immunoassays\, etc.).\nEffectively work in a cross-functional team environment\, interacting with various levels within the organization as well as vendors/academic sites/KOLs\nOrganization\, orientation to details\, and effective time management with an ability to adapt to changing priorities \nExcellent interpersonal and communication skills.\nMust be able to work effectively on multiple oncology programs in a fast dynamic environment.
URL:https://ces.b2sg.org/event/abbvie-26dec17/
LOCATION:AbbVie – Lake County\, IL\, Lake County\, IL\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20171228
DTEND;VALUE=DATE:20180131
DTSTAMP:20260818T052704
CREATED:20171228T190148Z
LAST-MODIFIED:20171228T190148Z
UID:19541-1514419200-1517356799@ces.b2sg.org
SUMMARY:Postdoctoral Associate
DESCRIPTION:The Human Genetics Department at the University of Miami Miller School of Medicine has an exciting opportunity for a Postdoctoral Associate. This position will carry out advanced independent and/or directed research to achieve the objectives of the research project. Duties assigned to this position will require an in-depth knowledge of a specialized field\, process\, and discipline and may involve organizing and implementing complex research plans\, the development of methods of research\, testing and data collection\, analysis and evaluation\, and writing reports containing descriptive\, analytical\, and evaluative content. The duties will require the exercise of independent discretion and judgment in carrying out research activities within the predetermined research scope and methodology. The Postdoctoral Associate will assist the Principal Investigator\, who is also the Director of the Cancer Epigenetics Research Program. The Postdoctoral Associate will conduct research and ensure that all experiments are appropriately conducted following the policies and procedures of the University of Miami.\nThe minimum qualifications for this position are as follows: Ph.D. in a relevant discipline involving cell/molecular biology\, immunology\, or stem cell. Must have experience in human cell/tissue culture\, molecular biological techniques\, experimental experience with studies in epigenetics and cancer research. Ability to plan\, organize\, and meet deadlines. Must be highly motivated. Ability to pay close attention to detail\, ensuring accuracy in work. Must be a self-starter with strong interpersonal skills. Proficiency and experience using Microsoft Word\, Excel\, and PowerPoint. Ability to manage multiple tasks simultaneously and independently. Ability to apply logic and demonstrate problem solving techniques. Excellent communication skills\, both verbal and written\, with strong presentation skills.
URL:https://ces.b2sg.org/event/umiami-28dec17/
LOCATION:University of Miami\, 1320 S Dixie Hwy\, Coral Gables\, FL\, 33146\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/07/u-miami-health.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20171230
DTEND;VALUE=DATE:20180202
DTSTAMP:20260818T052704
CREATED:20171230T210510Z
LAST-MODIFIED:20171230T210510Z
UID:19546-1514592000-1517529599@ces.b2sg.org
SUMMARY:Research Fellow
DESCRIPTION:A full-time post-doctoral computational biologist position is available in the Knoechel Lab Institute (http://knoechellab.dana-farber.org/) in the Department of Pediatric Oncology at the Dana-Farber Cancer for a highly motivated computational biologist to join our translational and basic research efforts in cancer epigenetics. Our research focuses on the application of epigenomic approaches and low cell number technologies to discover new disease mechanisms and exploit them therapeutically.  Specifically\, we are interested in 1) Deciphering epigenetic mechanisms of drug resistance in lymphoid malignancies\, 2) Understanding the basic biology of epigenetic aberrations in cancer\, with a particular focus on pediatric tumors\, and 3) Translating bench discovery to clinical care. \n\nThe qualified candidate will focus on new approaches for the analysis of epigenetic\, genomic and transcriptome sequencing data to enable new discoveries in patients in multiple contexts. We seek someone with experience in data analysis who is excited about generating new biological insights by applying existing methods to novel datasets\, and by developing new approaches to analyzing these data. \n\nThe person hired for this position will participate in the design and implementation of algorithms to analyze the data and integrate with other data sets including clinical outcomes data. This person will also help with the generation of tools needed for manipulating and preparing data for display and will also help maintain\, support\, and document shared tools\, code base\, and data sets. As the software infrastructure evolves\, this position is likely to present diverse and flexible opportunities. The computational biologist will interact and collaborate closely with other laboratory-based scientists and computational biologists across the Dana-Farber Cancer Institute and the BROAD Institute\, and will be involved in a series of research activities including cellular and molecular cancer biology. \n\n\nCharacteristic duties: \n\nApplying existing statistical and computational methods to novel datasets\nDeveloping and maintaining computational tools\nAnalyzing next generation sequencing data including ChIP-Seq\, ATAC-seq\, RNA-Seq\, etc.\nExplore existing literature to support and extend conclusions.\nPrepare research results for publication and for presentations at scientific meetings.\n\n\n\n\n\n\n\n\nJob Qualifications \nPhD\, MD\, or MD/PhD \n\nRequirements: \n\nTop-tier PhD in bioinformatics\, genetics\, epigenetics\, statistics\, mathematical\, physical\, or computer science\, or or a related discipline with significant experience in computer programming and computational biological applications\nExperience managing and curating large datasets and with machine learning techniques desired. Excellent oral and written communication skills are required.\nAbility to perform both self-directed and guided research are required.\nMust demonstrate outstanding personal initiative and the ability to work effectively as part of a team.\nAbility to meet deadlines and efficiently multitask is a must.\nTwo-year commitment is required.
URL:https://ces.b2sg.org/event/danafarber-30dec17/
LOCATION:Dana-Farber Cancer Institute\, 450 Brookline Avenue\, Boston\, MA\, 02215\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/11/Dana-Farber.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20171230
DTEND;VALUE=DATE:20180202
DTSTAMP:20260818T052704
CREATED:20171230T211339Z
LAST-MODIFIED:20171230T211339Z
UID:19548-1514592000-1517529599@ces.b2sg.org
SUMMARY:Research Associate
DESCRIPTION:Must have Ph.D.\, M.D.\, or equivalent.  Must have experience in one or more of the following areas: tumor immunology\, animal models\, immunological techniques to study the role of various proteins in tumor development\, molecular and cellular biology\, cancer cell biology\, protein crystallography\, biological computation/informatics\, stem cell regulation\, signal transduction\, gene expression\, epigenetics\, drug development\, functional genomics\, molecular carcinogenesis\, chemoprevention\, cancer therapeutics or other areas of cancer research.  Applicants should be creative\, organized\, highly motivated and capable of working independently as well as in a team approach.   \n\nDr. Zigang Dong’s Cellular and Molecular Biology lab currently has an opening for a Research Associate.  Responsibilities include participation in the design\, implementation and evaluation of research projects\, defining and solving scientific problems\, carrying out laboratory experiments\, developing experimental procedures\, collecting and analyzing data\, and preparing manuscripts for publication. \n\nDr. Zigang Dong’s Cellular and Molecular Biology lab currently has an opening for a Research Associate.  Responsibilities include participation in the design\, implementation and evaluation of research projects\, defining and solving scientific problems\, carrying out laboratory experiments\, developing experimental procedures\, collecting and analyzing data\, and preparing manuscripts for publication.
URL:https://ces.b2sg.org/event/myu-30dec17/
LOCATION:University of Minnesota\, St Paul\, MN\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/12/The-University-of-Minnesota.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20171230
DTEND;VALUE=DATE:20180202
DTSTAMP:20260818T052704
CREATED:20171230T211913Z
LAST-MODIFIED:20171230T211913Z
UID:19550-1514592000-1517529599@ces.b2sg.org
SUMMARY:Postdoctoral Associate
DESCRIPTION:A postdoctoral position is immediately available in the EpiCenter in the Department of Pediatrics at Baylor College of Medicine in Houston\, Texas. The research will focus on determining the molecular mechanisms underlying adverse pediatric outcomes. The successful candidate will employ integrative molecular epidemiologic methods for the assessments of adverse pediatric outcomes\, including structural birth defects and childhood cancer. The individual will work with genetic\, epigenetic\, and metabolomic data. The goal of this work will be to identify novel molecular predictors of adverse pediatric outcomes. The candidate will also be involved in the EpiCenter’s growing activities in global health. Successful candidates will be expected to tackle challenging scientific problems\, develop and optimize epidemiologic analytic pipelines\, and contribute to the positive and energetic work environment of the EpiCenter. \nRequired: \n\nPhD in Epidemiology
URL:https://ces.b2sg.org/event/baylor-30dec17/
LOCATION:Baylor College of Medicine\, 1 Baylor Plaza\, Houston\, TX\, 77030\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/05/bcm-baylor-e1494304823632.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20171230
DTEND;VALUE=DATE:20180202
DTSTAMP:20260818T052704
CREATED:20171230T212529Z
LAST-MODIFIED:20171230T212529Z
UID:19552-1514592000-1517529599@ces.b2sg.org
SUMMARY:Associate Research Scientist
DESCRIPTION:The Department of Pathology and Cell Biology at the Columbia University Medical Center is recruiting an Associate Research Scientist in the laboratory of Dr. Kevin Gardner. The incumbent will study the basic mechanisms of epigenetic gene regulation in breast cancer. The position will have an integrated focus on fundamental mechanisms of chromatin-based transcriptional control and epigenetic regulation with an emphasis on the role of metabolic imbalance in regulating these pathways in breast cancer (Proc Natl Acad Sci U S A. 2009 Nov 17;106(46):19286-91; Nat Struct Mol Biol. 2010 Dec;17(12):1406-13; Nat Commun. 2012 Jan 17;3:633; Nat Commun. 2013;4:1449). Major goals include understanding the role of metabolism and transcriptional cross-talk between epigenetic co-regulators and hormone receptor-mediated signaling pathways in both enhancer function and promoter-targeted mechanisms of gene control. An essential component of this work will involve developing omic perspectives that will integrate next-generation sequencing with genomics\, transcriptomics\, epigenomics\, proteomics and metabolomics using model systems and patient-derived samples. The projects will be supported by access to an established cohort of diverse breast cancer patient samples with extensive molecular and genomic characterization to aid in developing translation perspectives in gene-network and pathway discovery that will have practical implications for improving breast cancer diagnosis\, treatment\, and prevention.  \nOther responsibilities will include:  \nManaging the day to day operations of the laboratory. \nMaintenance of cell lines and carrying out immunoprecipitation assays. Ordering and maintaining inventory of laboratory supplies. Keeping track of orders and confirming billing. Setting up and performing experiments involving tissue culture\, western blot\, DNA\, RNA\, analysis. Maintaining records pertaining to the laboratory\, including records of experimental results. \nOperating\, maintaining and troubleshooting complex equipment (e.g. ABI 7300 Real-Time PCR system). \nAssisting in the training of new hires and other supporting staff. Enforcing safety regulations and helping to train students and fellows in laboratory procedures. Performing other related duties as necessary to the functioning of the laboratory.  
URL:https://ces.b2sg.org/event/columbia-30dec17/
LOCATION:Columbia University Medical Center\, 630 W 168th St\, New York\, NY\, 10032\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/11/Columbia-University-Medical-Center.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20171231
DTEND;VALUE=DATE:20180203
DTSTAMP:20260818T052704
CREATED:20171231T111220Z
LAST-MODIFIED:20171231T111452Z
UID:19556-1514678400-1517615999@ces.b2sg.org
SUMMARY:Epigenetics Specialist
DESCRIPTION:Required Skills: \n\nExtensive experience identifying epigenetic signatures resulting from pathology (such as viral infection or cancer)\nExperience with high-throughput assays for identifying epigenetic modifications (e.g.\, next-gen sequencing\, microarrays\, pyrosequencing\, etc.)\nDemonstrated experience analyzing genome-wide methylation profiling or chromatin remodeling\nKnowledge of virology or other infectious disease models strongly preferred\nStrong oral\, written\, and interpersonal communication skills and abilities;\nDemonstrated time management and completion of tasks to a definite deadline\nBioinformatics experience (e.g.\, experience working in a Linux environment and common scripting languages) is desirable\nCandidates must be willing to submit and be eligible for a DoD secret clearance (i.e.\, must be subject to and pass a background investigation and must be a U.S. citizen). \nMust be able to do extended deskwork at a computer\nMust be able to stand for several hours at a time to perform lab work\nMust be able to wear standard PPE (e.g.\, mask\, gloves\, lab coat) for extended periods of time    \n\n  \nPrimary Responsibilities: \n\nLead efforts based on the identification of epigenetic biomarkers of exposure to biological and chemical pathogens. Support experimental design\, development and optimization of biomarker identification methods and workflows\, and data analysis to validate prospective markers.\nLead and/or support technical tasks or projects within a collaborative teaming environment. The Epigenetics Specialist will work within a team of molecular biologists\, forensic scientists\, biochemists\, bioinformaticians\, database managers\, statisticians\, and project managers to provide solutions to maximize the utility\, confidence\, and rapid reporting of results for large epigenetic datasets.  \nSupport projects through employing efficient and accurate data evaluation techniques\, placing levels of statistical confidence on data output\, and clearly reporting results.\nInteract with clients (on and off-site) and present technical data through presentations and report writing.\nSupport end user trainings and client interactions.\nHelp grow the biological sciences business area through the successful and timely execution of projects\, positive interactions with clients\, recognition of opportunities for follow-on work with existing clients\, establishment of new opportunities with alternate clients\, proposal development and writing support\, and maintaining a presence at marketing and business development meetings/conferences.\nTravel to project and business development meetings as needed.\nReport directly to the biology Business Area Manager under the advisement of the Director of Biological Sciences.
URL:https://ces.b2sg.org/event/sigsci-31dec17/
LOCATION:Signature Science LLC\, 8329 N. Mopac Expressway\, Austin\, TX\, 78759\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/12/Signature-Science-1-1.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20171231
DTEND;VALUE=DATE:20180203
DTSTAMP:20260818T052704
CREATED:20171231T112321Z
LAST-MODIFIED:20171231T112321Z
UID:19562-1514678400-1517615999@ces.b2sg.org
SUMMARY:Assistant/ Associate/ Full Professor
DESCRIPTION:The Department of Cancer Biology at The University of Texas MD Anderson Cancer Center invites applicants for a full-time term tenure track academic appointment at the level of Assistant\, Associate\, or Full Professor. We seek exceptional scientists or physician scientists with demonstrated dedication to solving fundamental questions about the origin\, progression\, dissemination\, and resistance to therapy of cancer as well as basic scientists working on fundamental processes relevant to cancer. The successful applicant will develop a hypothesis-driven basic and translational research program in the field of general biology\, cancer pathogenesis\, cancer biology\, or cancer genetics. Preference will be given to candidates committed to conduct mechanistic studies by employing a variety of approaches\, ranging from genomics\, mouse modeling\, and biochemistry to high-resolution in vivo imaging. A secondary appointment in an appropriate clinical or basic science department will be considered. Areas of interest include – but are not limited to – epigenetics\, cell fate determination\, structural biology\, tumor microenvironment and cell signaling. \nThe position offers enormous opportunities for professional growth and development. The successful candidate will join an exciting and active group of investigators\, including Ron DePinho\, Filippo Giancotti\, Jian Hu\, Raghu Kalluri\, Valerie LeBleu\, Randy Johnson\, Katharina Schlacher\, and among others. The joint faculty of the department include James P. Allison\, David Piwnica-Worms\, John Tainer and others. The faculty member will have access to the department’s substantial resources\, including cutting edge core facilities\, animal models\, and educational/training programs. A very generous start-up package is available for the Faculty member’s research program; furthermore\, it is anticipated that successful candidates will have the scientific caliber and accomplishments to compete successfully for a Recruitment Award from the Cancer Research and Prevention Institute of Texas (CPRIT) and The University of Texas Regents Funding. Refer to the Department of Cancer Biology Web page for additional information about the department and its programs.
URL:https://ces.b2sg.org/event/mdanderson-31dec17/
LOCATION:MD Anderson Cancer Center\, 1515 Holcombe Blvd\, Houston\, TX\, 77030\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/05/MDAnderson.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20171231
DTEND;VALUE=DATE:20180301
DTSTAMP:20260818T052704
CREATED:20171231T113056Z
LAST-MODIFIED:20171231T113056Z
UID:19564-1514678400-1519862399@ces.b2sg.org
SUMMARY:Assistant/Associate Professor
DESCRIPTION:The Department of Pathology and Laboratory Medicine at the Perelman School of Medicine at the University of Pennsylvania seeks candidates for an Associate or Assistant Professor position in the tenure track. The successful applicant will have experience in the field of Genome Editing & Functional Cancer Genomics and will creatively leverage the CRISPR/Cas9 or similar technologies towards functional characterization of chromosomal translocations\, candidate drive mutations\, epigenetic alterations\, genetic polymorphisms\, etc. Identification of new susceptibility alleles in important pediatric cancers and related diseases is also a priority. Responsibilities include establishing and maintaining an independent\, extramurally funded research program. Teaching and mentoring of graduate and medical students is an integral component of this position. Applicants must have an M.D./Ph.D or equivalent degree and have demonstrated excellent qualifications in research and education. \nThe position is affiliated with the Division of Cancer Pathobiology & the Center for Childhood Cancer Research at the Children’s Hospital of Philadelphia (CHOP). The Division & CCCR are housed in the state-of-the-art Colket Translational Research Building. More information about the program can be found at: http://www.chop.edu/cccr/research-topic/cancer-pathobiology-research 
URL:https://ces.b2sg.org/event/upenn-31dec17/
LOCATION:University of Pennsylvania\, 3400 Civic Center Blvd\, Philadelphia\, 19104\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20171231
DTEND;VALUE=DATE:20180203
DTSTAMP:20260818T052704
CREATED:20171231T113901Z
LAST-MODIFIED:20171231T114008Z
UID:19568-1514678400-1517615999@ces.b2sg.org
SUMMARY:Senior Research Worker
DESCRIPTION:A Senior Research Worker is available in Dr. Chao Lu’s lab investigating molecular mechanisms of chromatin and epigenetic regulation and its implications for human cancer. The senior research worker will serve as a lab manager in charge of ordering supplies\, maintaining lab stocks and maintaining transgenic mouse breeding colonies\, including genotyping and husbandry. He/she will also supervise and perform molecular and cell biology experiments\, epigenetic assays\, and tissue histology/imaging. The candidate will be responsible for data collection and computer entry and will carry out research projects under supervision. We offer competitive salary. To learn more about the research laboratory. please visit: www.chaolulab.com. \nMinimum Qualifications for Grade\n Applicant MUST meet these minimum qualifications to be considered an applicant \nMaster’s degree and at least three years experience\, or Bachelor’s degree and at least five years of related experience or equivalent in education\, training\, and experience. 
URL:https://ces.b2sg.org/event/columbia-31dec17/
LOCATION:Columbia University Medical Center\, 630 W 168th St\, New York\, NY\, 10032\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20171231
DTEND;VALUE=DATE:20180203
DTSTAMP:20260818T052704
CREATED:20171231T115248Z
LAST-MODIFIED:20171231T115248Z
UID:19571-1514678400-1517615999@ces.b2sg.org
SUMMARY:Translational Research Project Leader
DESCRIPTION:We are looking to add an integral member to our team who will join a fast-paced department and be able to juggle multiple and evolving priorities. \nWe are a small\, agile\, and cross-functional team – so we need a dynamic self-starter to hit the ground running and work well in a fluid\, collaborative setting! \nAs a Translational Research Project Leader on our team\, you will be responsible for managing and overseeing clinical trial correlative research projects. We currently are involved in six ongoing multi-institutional early phase trials involving epigenetics agents used in combination in hematologic and solid tumor malignancies with robust correlative research efforts. All of these trials are conducted in partnership with our member institutions\, including Fox Chase\, Johns Hopkins\, Memorial Sloan Kettering\, University of Copenhagen/Rigshospitalet\, University of Southern California\, University of Maryland\, and Temple University. Additionally\, we rely and value our rich partnerships with the pharmaceutical industry. Learn more about VARI-SU2C here. \nDuties include\, but not limited to: \nManaging Correlative Research Projects \n\nPlan\, coordinate\, and oversee the execution of correlative research coordinated by VARI for the VARI-SU2C program.\nIn a customer service-oriented manner discuss the plans for correlative research\, data analysis\, and deliverables with the clinical trial PIs\, consortium members\, VARI investigators and research staff\, and collaborators.\nCoordinate the development and implementation of correlative research SOPs including raw assay analyses\, data upload\, data storage\, genomic data storage\, clinical data coding/de-identification\, etc.\n\nBioinformatics & Data Management \n\nOversee the development of data hub for VARI-SU2C consortium.\nInterpret bioinformatics data.\nOversee database and report setup\, as well as processing and cleaning correlative research data\, following all applicable standard and study-specific procedures.\n\n\nThe Education and Skills We Expect You to Possess: \n\n\nA Ph.D. or M.S. degree in life science or computer science\, with a degree in computational biology preferred.\n3 -5 years of experience of translational research experience\, specifically related in genetic and epigenetic sequencing assays\nPrevious data analysis project management leadership experience.\nDemonstrated knowledge of command line bioinformatics software and basic knowledge of data pipelines. Knowledge of database design (e.g.\, SQL\, Access\, etc.).\nExcellent verbal and written communication and interpersonal skills and significant customer service background and skills.
URL:https://ces.b2sg.org/event/vari-31dec17/
LOCATION:Van Andel Research Insitute\, Grand Rapis\, MI\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180102
DTEND;VALUE=DATE:20180204
DTSTAMP:20260818T052704
CREATED:20180102T132915Z
LAST-MODIFIED:20180102T133149Z
UID:19578-1514851200-1517702399@ces.b2sg.org
SUMMARY:Postdoctoral Fellow
DESCRIPTION:Postdoc Positions Focusing on Gene Regulation in Cancer Progression \nMultiple postdoctoral positions are available in the laboratory of Dr. Jason Liu (http://molecularmedicine.uthscsa.edu/FAC_Research.aspx?facID=206) in the Department of Molecular Medicine at the University of Texas Health Science Center at San Antonio \nThe focus of the lab is studying enhancer function and epigenetic mechanism in gene regulation in cancer progression. Selected candidates will perform highly interdisciplinary and collaborative scientific research in one or more of the following projects\, working with human cell lines\, mouse models and clinical samples: \n(1) Explore the function of signaling-regulated enhancers in breast and prostate cancers\, and understand how enhancers are regulated by the crosstalk of different signaling pathways including sex hormones\, inflammation signals and metabolic signals; \n(2) Decipher the epigenetic and chromatin 3D level changes in enhancers upon developmental/pathological stimuli or during hormone/drug resistance acquisition; \n(3) Identify diagnostic/prognostic biomarkers and therapeutic targets for cancer and develop drugs for pre-clinical studies and potential clinical applications. \nOur research integrates next-generation sequencing (NGS)-based technologies and bioinformatics tools to investigate the component\, epigenetic\, and 3D level changes of enhancers in cancers \n(refer to Cell\, 2014 159: 358–373). We are efficiently combining biochemical\, cellular\, and animal model-related studies with different NGS-based assays. Our research program will help the trainees from both wet and dry lab sides to build up strong expertise and training record in molecular biology and multi-omics (genomics\, transcriptomics\, proteomics\, epigenomics and metabolomics). \nPositions require a Ph.D. degree (or equivalent) in biochemistry\, cell biology\, cancer biology\, bioinformatics\, or closely related biological sciences. The candidates need to have high motivation and strong molecular biology background. Any prior experience in patient-derived xenograft (PDX) models\, breast/prostate cancer\, and computational analyses will be valued. \nSan Antonio is one of the fastest growing cities. The UTHSCSA is the largest university of health science in South Texas and one of four medical schools in the UT System. The affiliated Cancer Therapy & Research Center (CTRC) is one of the NCI-designated national cancer centers in the state of Texas. A competitive salary and benefits package will be provided. \nTo apply: \nPlease send the application package in one single pdf file including a cover letter briefly describing your previous experience and your future research interest/plan\, curriculum vitae with list of publications\, and contact information of at least three references to the following email. You are also welcome to send any inquiries or questions you might have. \nContact information: \nDr. Jason Liu \nDepartment of Molecular Medicine \nThe University of Texas Health Science Center at San Antonio \n7703 Floyd Curl Drive \nSan Antonio\, TX\, 78229-3900 \nEmail: LiuZ7@uthscsa.edu
URL:https://ces.b2sg.org/event/uthscsa-2feb18/
LOCATION:UT Health Science Center in San Antonio\, 7703 Floyd Curl Drive\, San Antonio\, TX\, 78229\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180103
DTEND;VALUE=DATE:20180205
DTSTAMP:20260818T052704
CREATED:20180103T113456Z
LAST-MODIFIED:20180103T113456Z
UID:19584-1514937600-1517788799@ces.b2sg.org
SUMMARY:Postdoctoral Fellow
DESCRIPTION:A postdoctoral position is available to work at the interface of cancer epigenetics and translational therapeutics for head and neck malignancies. The position will be supported by a new NIH R01 award and industry-sponsored agreements in the Division of Head and Neck Surgery at the University of Pennsylvania Perelman School of Medicine. Our research program aims to develop novel approaches to target the tumor cell fractions within individual cancers that are innately resistant to current therapies. Studies will emphasize molecular and functional definition of the epigenetically distinct cell states within a heterogeneous tumor that contribute to treatment failure. Work will rely upon advanced in vitro cancer models\, patient-derived xenografts\, and human tumor specimens. Significant prior experience in epigenetics\, cancer biology\, bioinformatics\, stem cell biology\, and/or biochemistry is desirable. Training and career development will also be supported by investigators in a P01-funded program in esophageal squamous cell carcinoma in the Division of Gastroenterology. Applicants authorized for employment in the United States are strongly preferred. However visa sponsorship may be considered for an exceptional foreign applicant with well-developed English writing ability. Interested individuals should send cover letter\, CV\, and detailed reference information\, including most recent research supervisor\, by e-mail to: \nDevraj Basu\, M.D\, Ph.D.\, F.A.C.S.\nAssistant Professor \nDepartment of Otorhinolaryngology-Head and Neck Surgery \nThe University of Pennsylvania\n3600 Spruce St.\, 5 Ravdin/Silverstein \nPhiladelphia\, PA 19104 \nemail: devraj.basu@uphs.upenn.edu \nhttp://www.med.upenn.edu/apps/faculty/index.php/g275/p8137952
URL:https://ces.b2sg.org/event/upenn-3jan18/
LOCATION:University of Pennsylvania\, 3400 Civic Center Blvd\, Philadelphia\, 19104\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180103
DTEND;VALUE=DATE:20180205
DTSTAMP:20260818T052704
CREATED:20180103T114123Z
LAST-MODIFIED:20180103T114237Z
UID:19587-1514937600-1517788799@ces.b2sg.org
SUMMARY:Postdoctoral Associate
DESCRIPTION:A postdoctoral position is immediately available in the EpiCenter in the Department of Pediatrics at Baylor College of Medicine in Houston\, Texas. The research will focus on determining the molecular mechanisms underlying adverse pediatric outcomes. The successful candidate will employ integrative molecular epidemiologic methods for the assessments of adverse pediatric outcomes\, including structural birth defects and childhood cancer. The individual will work with genetic\, epigenetic\, and metabolomic data. The goal of this work will be to identify novel molecular predictors of adverse pediatric outcomes. The candidate will also be involved in the EpiCenter’s growing activities in global health. Successful candidates will be expected to tackle challenging scientific problems\, develop and optimize epidemiologic analytic pipelines\, and contribute to the positive and energetic work environment of the EpiCenter. \nRequired: \n\nPhD in Epidemiology
URL:https://ces.b2sg.org/event/baylor-3jan18/
LOCATION:Baylor College of Medicine\, 1 Baylor Plaza\, Houston\, TX\, 77030\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180103
DTEND;VALUE=DATE:20180205
DTSTAMP:20260818T052704
CREATED:20180103T115322Z
LAST-MODIFIED:20180103T115322Z
UID:19589-1514937600-1517788799@ces.b2sg.org
SUMMARY:Postdoc
DESCRIPTION:A postdoctoral position is immediately available within the Masri Lab at the University of California\, Irvine (UC Irvine). The Masri lab employs a systemic approach to understanding cancer metabolism that is linked to the circadian clock\, the biological pacemaker that regulates diurnal physiology. We are interested in two research questions. The first question relates to how genetic disruption of the circadian clock in mouse models alters tumorigenesis both at the level of initiation and disease progression. The second question is aimed at elucidating the systemic crosstalk between tumors and peripheral tissues and how cancer cells are able to rewire circadian metabolism at a distance.  \nWe are seeking independent and motivated postdoctoral candidates interested in a multi-disciplinary approach to tumorigenesis including: cancer metabolism\, circadian clock disruption\, and transcription and epigenetic control. The Masri lab utilizes genetic mouse models\, molecular and cell biology\, as well as genome-wide ‘omics’ approaches to determine changes in gene expression programs\, histone modifications\, and alterations in metabolites using metabolomics. In addition\, bioinformatics expertise is an advantage\, but certainly not required. Experience with mouse handling and experiments\, mammalian cell culture\, and routine molecular and cell biology are needed. Also\, at least 1 first author publication from the Ph.D. training period is required.  \nFor consideration\, applicants may send an email to Professor Selma Masri ( Masrilaboratory@gmail.com) with the following information:  \n\nBrief statement of research interests and future goals\nCV detailing research experience\, publications\, any fellowships obtained during the training period\, and other relevant information\nList of any manuscripts in preparation or currently under review\nNames of 3 references that are familiar with the research experience of the candidate and can provide letters of recommendation upon request
URL:https://ces.b2sg.org/event/ucirvine-3jan18/
LOCATION:UC Irvine\, Irvine\, CA\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180104
DTEND;VALUE=DATE:20180207
DTSTAMP:20260818T052704
CREATED:20180104T163049Z
LAST-MODIFIED:20180104T163049Z
UID:19594-1515024000-1517961599@ces.b2sg.org
SUMMARY:Scientist - Computational Biology
DESCRIPTION:Client Quanticel Research\, a drug division of Client Pharmaceuticals\, is committed to the development of breakthrough medicines for the treatment of cancer. Our proprietary platform for single-cell analysis of the cancer genome enables the discovery of first-in-class oncology therapeutics.  \nCQR seeks a scientist to join our vibrant interdisciplinary team to develop and facilitate interpretation of complex next-generation sequencing data from tumor xenografts and derived single-cells. The right candidate will share our passion for pioneering new solutions\, continual improvement\, and uncompromising quality in research.  \nResponsibilities will include\, but are not limited to\, the following:  \n\nAdapt open source tools and/or develop visualization methods to enable bench scientists to query\, display and interpret NGS data types. These include RNA-expression from single-cells and bulk tissues\, variant data from exome sequencing\, copy-number data from whole genome sequencing\, and epigenetic data.\nFacilitate data sharing/management from internal and open-source based databases.\nAbility to integrate laboratory instrument metadata to databases\n\nSkills/Knowledge Required: \n\nProficiency in shell scripting\, Django/Python\, R/Shiny\, SQL and JavaScript. Java considered a plus.\nComfortable working in Linux and Docker environments.\nGeneral knowledge of NGS technologies\, sequence analysis tools and public visualization resources.\nExperience with Amazon EC2 cloud resources; e.g. S3\, EC2\, Lambda and others.\nHighly self-motivated and enjoy working as part of a multi-disciplinary team\nOutstanding oral and written communication skills\n\nFunctional/Scientific/Technical Skills: \n\nAble to critically structure data.\nPossess in-depth knowledge in some area of data visualization\nUnderstands fundamental scientific problems and can apply knowledge to research and development projects and problems in a positive manner.\nContributes individually as well as on cross functional teams.\nResponsible for more complex assignments and for more than one project.
URL:https://ces.b2sg.org/event/advent-4jan18/
LOCATION:Advent Global Solutions\, San Francisco\, CA\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180104
DTEND;VALUE=DATE:20180207
DTSTAMP:20260818T052704
CREATED:20180104T163924Z
LAST-MODIFIED:20180104T164017Z
UID:19598-1515024000-1517961599@ces.b2sg.org
SUMMARY:Research Assistant
DESCRIPTION:The Wistar Institute has an opening for a Research Assistant in the laboratory of Dr. Rugang Zhang to perform research in which explores epigenetic approaches to ovarian cancer using tissue culture and patient-derived xenograft models.  \nThe candidate will work on a project sponsored by a pharmaceutical company to explore epigenetic therapy in ovarian cancer. The candidate will have ample opportunity to learn cutting-edge experimental techniques and clinically relevant preclinical ovarian cancer models. Duties include\, but are not limited to\, experiments in molecular biology\, cell biology\, tissue culture and mouse models of ovarian cancer.  \nBS/BA in biology or related field. Experience working in a lab is desirable but not required.  \nThe Wistar Institute is located in the University City area of Philadelphia\, in the heart of the University of Pennsylvania Campus. Wistar provides resources to its faculty and staff that enable them to conduct cutting edge collaborative research and provides for outstanding intellectual environments and state-of-the-art facilities. Research discoveries conducted at Wistar have led to the development of vaccines; the identification of genes associated with cancers; and the development of many other significant research technologies and tools. 
URL:https://ces.b2sg.org/event/wistar-4dec18/
LOCATION:Wistar Institute\, 3601 Spruce Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180114
DTEND;VALUE=DATE:20180216
DTSTAMP:20260818T052704
CREATED:20180114T105829Z
LAST-MODIFIED:20180114T105829Z
UID:19606-1515888000-1518739199@ces.b2sg.org
SUMMARY:Postdoctoral Scientist
DESCRIPTION:The Biochemistry and Molecular Medicine department is looking for a candidate that will work under the direct supervision of Dr. Mei-Yi Wu. He or she will be responsible for carrying out the research experiments. He or she will also participate in the weekly lab meeting\, and present and discuss the progress of the project with Dr. Mei-Yi Wu.  \nThe project focuses on two epigenetic modulators and members of the AT-rich interaction domain family\, ARID4A and ARID4B. Epigenetics plays an important role in human health and disease. Disruption of epigenetic modifications leads to dysregulation of gene function without altering the DNA sequence per se. A major challenge in understanding the importance of epigenetics in human health and diseases is to identify the specific epigenetic factors and the signaling involved. Currently\, we are investigating the role of ARID4A and ARID4B in development and cancer disease using state-of-the-art conditional knockout mouse models and genomic and proteomic approach. We also study the role of ARID4B in cancer stem cells that have been suggested as the major cause for therapy resistance and the driving force behind cancer metastasis and relapse. To investigate whether and how ARID4B drive cancer development\, we evalute the underlying molecular mechanisms by which ARID4B promotes therapy resistance and aggressive cancer.  \nDuties include: \n-Culture and transfection of mammial cells \n-Collecting samples for reporter gene assays \n-Western blooting to analyze protein expression \n-Cancer cell migration and invasion assays \n-Human cancer xenogrant experiments using SCID / NOD mice \n-The postdoc will also work with genetically modified mice \n-Ordering lab supplies\, lab maintenance and other duties as assigned \n-This position performs other duties as assigned. The omission of specific duties does not preclude the supervisor from assigning duties that are logically related to the position.  \nMinimum Qualifications: \nQualified candidates will hold a PhD in a related discipline. Degree must be conferred by the start date of the position  \nAdditional Required Licenses/Certifications/Posting Specific Minimum Qualifications:  \nPreferred Qualifications: \nPh.D. degree\, with experience in molecular and cellular biology. 
URL:https://ces.b2sg.org/event/gwu-14jan18/
LOCATION:George Washington University\, 2121 I St NW\, Washington\, DC\, 20052\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180114
DTEND;VALUE=DATE:20180216
DTSTAMP:20260818T052704
CREATED:20180114T110932Z
LAST-MODIFIED:20180114T111008Z
UID:19608-1515888000-1518739199@ces.b2sg.org
SUMMARY:Research Scientist
DESCRIPTION:RESEARCH SCIENTIST\, Koch Institute (KI) for Integrative Cancer Research-J&J Lung Cancer Initiative Collaboration (multiple positions)\, to contribute to three KI laboratories involved in research regarding the discovery and development of therapeutics and diagnostics that may be useful treating\, preventing\, intercepting\, and/or diagnosing diseases specifically focused on lung cancer. The Jacks Laboratory will focus on genetic and epigenetic changes accompanying and controlling lung cancer initiation and progression; developing vaccines for disease interception; and the role of inflammation\, inflammatory cells\, and specific inflammatory mediators in lung cancer development. The Bhatia Laboratory will focus on novel diagnostic and early detection technologies\, including protease activity-based nanosensors and explore the utility of these technologies using human genomic data and genetically-engineered mouse models (GEMMs) of lung cancer to detect and stratify disease early enough for interception. The Irvine laboratory will focus on early interception using immunotherapy agents to detect and prophylactically protect from lung cancer and generate novel immune-based drugs and vaccine platforms\, especially focused on Kras-mutant lung tumors. These will be tested initially in GEMM models. Will contribute to executing research aims; establishing research strategy; reporting; and planning and writing animal and other protocols\, manuscripts\, and reports.  \nJob Requirements: \nREQUIRED: MD and/or Ph.D. in medicine and/or biomedical science; extensive knowledge of cancer biology and related fields; ability to conceptualize and write proposals and publishable manuscripts\, evaluate and train junior researchers\, innovate\, and conduct research; meticulous attention to detail; strong organizational\, documentation\, interpersonal\, and communication skills; comfort summarizing and reporting results; ability to work collaboratively\, follow safety procedures\, and maintain a safe work environment. Familiarity with physiology; cell and molecular biology; immunology; animal testing of biologics; materials science; and/or histological\, biochemical\, and mechanical analyses ideal. Job #15547  \nThis is a one-year\, term-limit appointment with an extension based on continued funding.
URL:https://ces.b2sg.org/event/mit-14jan18/
LOCATION:Koch Institute MIT\, Cambridge\, MA\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180114
DTEND;VALUE=DATE:20180216
DTSTAMP:20260818T052704
CREATED:20180114T153848Z
LAST-MODIFIED:20180114T153910Z
UID:19614-1515888000-1518739199@ces.b2sg.org
SUMMARY:Postdoctoral Associate
DESCRIPTION:Applications are invited from ambitious\, independent and motivated candidates to work with Professor Peter D. Adams to investigate the epigenetics of aging and cancer at Sanford Burnham Prebys Medical Discovery Institute\, San Diego. Specific projects in the lab range from development of novel epigenetic therapies to combat cancer (for example\, epigenetic therapies to synergize with immune therapies)\, to investigation of epigenetic mechanisms that contribute to age-associated increase in cancer. A long-term goal of the lab is to develop epigenetic-based approaches for cancer chemoprevention.  \nThe project will employ state-of-the-art molecular and cellular biology approaches\, including ChIP-seq\, RNA-seq\, ATAC-seq\, DNA methyl-seq and other large-scale epigenomic and chromatin analyses\, including at the single-cell level; high throughput chemical and RNAi/CRISPR phenotypic screens; cell imaging; state-of-the-art gene manipulations using RNAi and CRISPR technology. In addition\, we routinely employ sophisticated mouse models and human tissues.  \nThe lab strives to be highly collaborative with other labs in San Diego\, the US and elsewhere\, for example collaborating with computational biologists\, immunologists\, experts in specific mouse models of cancer and aging\, and surgeons\, pathologists and clinical oncologists. San Diego is an outstanding scientific environment and a fabulous place to live.  \nRequired Skills  \nRequired Experience  \nCandidates should have\, or be working towards\, a PhD or equivalent degree in a biological science. Expertise in an aspect of cell and/or molecular biology and/or animal models is essential. The lab has dedicated computational biology support for data analysis\, so computational expertise is an advantage\, but not essential. Successful applicants will be able to learn computational approaches for analysis of large datasets\, a big advantage in a competitive job market.  \nInterested candidates should submit one PDF with a summary of achievements and research interests\, updated CV and contact information for 3 letters of references.  \nLab website: https://chromatin.wordpress.com 
URL:https://ces.b2sg.org/event/sbp-14jan18/
LOCATION:Sanford Burnham Prebys Medical Discovery Institute\, 10901 N Torrey Pines Rd\, La Jolla\, CA\, 92037\, United States
CATEGORIES:Jobs
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