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METHOD:PUBLISH
X-WR-CALNAME:Cancer Epigenetics Society
X-ORIGINAL-URL:https://ces.b2sg.org
X-WR-CALDESC:Events for Cancer Epigenetics Society
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DTSTART:20170326T010000
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DTSTART:20171029T010000
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DTSTART:20181028T010000
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DTSTART;VALUE=DATE:20171231
DTEND;VALUE=DATE:20180203
DTSTAMP:20260818T180951
CREATED:20171231T111220Z
LAST-MODIFIED:20171231T111452Z
UID:19556-1514678400-1517615999@ces.b2sg.org
SUMMARY:Epigenetics Specialist
DESCRIPTION:Required Skills: \n\nExtensive experience identifying epigenetic signatures resulting from pathology (such as viral infection or cancer)\nExperience with high-throughput assays for identifying epigenetic modifications (e.g.\, next-gen sequencing\, microarrays\, pyrosequencing\, etc.)\nDemonstrated experience analyzing genome-wide methylation profiling or chromatin remodeling\nKnowledge of virology or other infectious disease models strongly preferred\nStrong oral\, written\, and interpersonal communication skills and abilities;\nDemonstrated time management and completion of tasks to a definite deadline\nBioinformatics experience (e.g.\, experience working in a Linux environment and common scripting languages) is desirable\nCandidates must be willing to submit and be eligible for a DoD secret clearance (i.e.\, must be subject to and pass a background investigation and must be a U.S. citizen). \nMust be able to do extended deskwork at a computer\nMust be able to stand for several hours at a time to perform lab work\nMust be able to wear standard PPE (e.g.\, mask\, gloves\, lab coat) for extended periods of time    \n\n  \nPrimary Responsibilities: \n\nLead efforts based on the identification of epigenetic biomarkers of exposure to biological and chemical pathogens. Support experimental design\, development and optimization of biomarker identification methods and workflows\, and data analysis to validate prospective markers.\nLead and/or support technical tasks or projects within a collaborative teaming environment. The Epigenetics Specialist will work within a team of molecular biologists\, forensic scientists\, biochemists\, bioinformaticians\, database managers\, statisticians\, and project managers to provide solutions to maximize the utility\, confidence\, and rapid reporting of results for large epigenetic datasets.  \nSupport projects through employing efficient and accurate data evaluation techniques\, placing levels of statistical confidence on data output\, and clearly reporting results.\nInteract with clients (on and off-site) and present technical data through presentations and report writing.\nSupport end user trainings and client interactions.\nHelp grow the biological sciences business area through the successful and timely execution of projects\, positive interactions with clients\, recognition of opportunities for follow-on work with existing clients\, establishment of new opportunities with alternate clients\, proposal development and writing support\, and maintaining a presence at marketing and business development meetings/conferences.\nTravel to project and business development meetings as needed.\nReport directly to the biology Business Area Manager under the advisement of the Director of Biological Sciences.
URL:https://ces.b2sg.org/event/sigsci-31dec17/
LOCATION:Signature Science LLC\, 8329 N. Mopac Expressway\, Austin\, TX\, 78759\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/12/Signature-Science-1-1.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20171231
DTEND;VALUE=DATE:20180203
DTSTAMP:20260818T180951
CREATED:20171231T112321Z
LAST-MODIFIED:20171231T112321Z
UID:19562-1514678400-1517615999@ces.b2sg.org
SUMMARY:Assistant/ Associate/ Full Professor
DESCRIPTION:The Department of Cancer Biology at The University of Texas MD Anderson Cancer Center invites applicants for a full-time term tenure track academic appointment at the level of Assistant\, Associate\, or Full Professor. We seek exceptional scientists or physician scientists with demonstrated dedication to solving fundamental questions about the origin\, progression\, dissemination\, and resistance to therapy of cancer as well as basic scientists working on fundamental processes relevant to cancer. The successful applicant will develop a hypothesis-driven basic and translational research program in the field of general biology\, cancer pathogenesis\, cancer biology\, or cancer genetics. Preference will be given to candidates committed to conduct mechanistic studies by employing a variety of approaches\, ranging from genomics\, mouse modeling\, and biochemistry to high-resolution in vivo imaging. A secondary appointment in an appropriate clinical or basic science department will be considered. Areas of interest include – but are not limited to – epigenetics\, cell fate determination\, structural biology\, tumor microenvironment and cell signaling. \nThe position offers enormous opportunities for professional growth and development. The successful candidate will join an exciting and active group of investigators\, including Ron DePinho\, Filippo Giancotti\, Jian Hu\, Raghu Kalluri\, Valerie LeBleu\, Randy Johnson\, Katharina Schlacher\, and among others. The joint faculty of the department include James P. Allison\, David Piwnica-Worms\, John Tainer and others. The faculty member will have access to the department’s substantial resources\, including cutting edge core facilities\, animal models\, and educational/training programs. A very generous start-up package is available for the Faculty member’s research program; furthermore\, it is anticipated that successful candidates will have the scientific caliber and accomplishments to compete successfully for a Recruitment Award from the Cancer Research and Prevention Institute of Texas (CPRIT) and The University of Texas Regents Funding. Refer to the Department of Cancer Biology Web page for additional information about the department and its programs.
URL:https://ces.b2sg.org/event/mdanderson-31dec17/
LOCATION:MD Anderson Cancer Center\, 1515 Holcombe Blvd\, Houston\, TX\, 77030\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/05/MDAnderson.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20171231
DTEND;VALUE=DATE:20180301
DTSTAMP:20260818T180951
CREATED:20171231T113056Z
LAST-MODIFIED:20171231T113056Z
UID:19564-1514678400-1519862399@ces.b2sg.org
SUMMARY:Assistant/Associate Professor
DESCRIPTION:The Department of Pathology and Laboratory Medicine at the Perelman School of Medicine at the University of Pennsylvania seeks candidates for an Associate or Assistant Professor position in the tenure track. The successful applicant will have experience in the field of Genome Editing & Functional Cancer Genomics and will creatively leverage the CRISPR/Cas9 or similar technologies towards functional characterization of chromosomal translocations\, candidate drive mutations\, epigenetic alterations\, genetic polymorphisms\, etc. Identification of new susceptibility alleles in important pediatric cancers and related diseases is also a priority. Responsibilities include establishing and maintaining an independent\, extramurally funded research program. Teaching and mentoring of graduate and medical students is an integral component of this position. Applicants must have an M.D./Ph.D or equivalent degree and have demonstrated excellent qualifications in research and education. \nThe position is affiliated with the Division of Cancer Pathobiology & the Center for Childhood Cancer Research at the Children’s Hospital of Philadelphia (CHOP). The Division & CCCR are housed in the state-of-the-art Colket Translational Research Building. More information about the program can be found at: http://www.chop.edu/cccr/research-topic/cancer-pathobiology-research 
URL:https://ces.b2sg.org/event/upenn-31dec17/
LOCATION:University of Pennsylvania\, 3400 Civic Center Blvd\, Philadelphia\, 19104\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20171231
DTEND;VALUE=DATE:20180203
DTSTAMP:20260818T180951
CREATED:20171231T113901Z
LAST-MODIFIED:20171231T114008Z
UID:19568-1514678400-1517615999@ces.b2sg.org
SUMMARY:Senior Research Worker
DESCRIPTION:A Senior Research Worker is available in Dr. Chao Lu’s lab investigating molecular mechanisms of chromatin and epigenetic regulation and its implications for human cancer. The senior research worker will serve as a lab manager in charge of ordering supplies\, maintaining lab stocks and maintaining transgenic mouse breeding colonies\, including genotyping and husbandry. He/she will also supervise and perform molecular and cell biology experiments\, epigenetic assays\, and tissue histology/imaging. The candidate will be responsible for data collection and computer entry and will carry out research projects under supervision. We offer competitive salary. To learn more about the research laboratory. please visit: www.chaolulab.com. \nMinimum Qualifications for Grade\n Applicant MUST meet these minimum qualifications to be considered an applicant \nMaster’s degree and at least three years experience\, or Bachelor’s degree and at least five years of related experience or equivalent in education\, training\, and experience. 
URL:https://ces.b2sg.org/event/columbia-31dec17/
LOCATION:Columbia University Medical Center\, 630 W 168th St\, New York\, NY\, 10032\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/11/Columbia-University-Medical-Center.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20171231
DTEND;VALUE=DATE:20180203
DTSTAMP:20260818T180951
CREATED:20171231T115248Z
LAST-MODIFIED:20171231T115248Z
UID:19571-1514678400-1517615999@ces.b2sg.org
SUMMARY:Translational Research Project Leader
DESCRIPTION:We are looking to add an integral member to our team who will join a fast-paced department and be able to juggle multiple and evolving priorities. \nWe are a small\, agile\, and cross-functional team – so we need a dynamic self-starter to hit the ground running and work well in a fluid\, collaborative setting! \nAs a Translational Research Project Leader on our team\, you will be responsible for managing and overseeing clinical trial correlative research projects. We currently are involved in six ongoing multi-institutional early phase trials involving epigenetics agents used in combination in hematologic and solid tumor malignancies with robust correlative research efforts. All of these trials are conducted in partnership with our member institutions\, including Fox Chase\, Johns Hopkins\, Memorial Sloan Kettering\, University of Copenhagen/Rigshospitalet\, University of Southern California\, University of Maryland\, and Temple University. Additionally\, we rely and value our rich partnerships with the pharmaceutical industry. Learn more about VARI-SU2C here. \nDuties include\, but not limited to: \nManaging Correlative Research Projects \n\nPlan\, coordinate\, and oversee the execution of correlative research coordinated by VARI for the VARI-SU2C program.\nIn a customer service-oriented manner discuss the plans for correlative research\, data analysis\, and deliverables with the clinical trial PIs\, consortium members\, VARI investigators and research staff\, and collaborators.\nCoordinate the development and implementation of correlative research SOPs including raw assay analyses\, data upload\, data storage\, genomic data storage\, clinical data coding/de-identification\, etc.\n\nBioinformatics & Data Management \n\nOversee the development of data hub for VARI-SU2C consortium.\nInterpret bioinformatics data.\nOversee database and report setup\, as well as processing and cleaning correlative research data\, following all applicable standard and study-specific procedures.\n\n\nThe Education and Skills We Expect You to Possess: \n\n\nA Ph.D. or M.S. degree in life science or computer science\, with a degree in computational biology preferred.\n3 -5 years of experience of translational research experience\, specifically related in genetic and epigenetic sequencing assays\nPrevious data analysis project management leadership experience.\nDemonstrated knowledge of command line bioinformatics software and basic knowledge of data pipelines. Knowledge of database design (e.g.\, SQL\, Access\, etc.).\nExcellent verbal and written communication and interpersonal skills and significant customer service background and skills.
URL:https://ces.b2sg.org/event/vari-31dec17/
LOCATION:Van Andel Research Insitute\, Grand Rapis\, MI\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180102
DTEND;VALUE=DATE:20180204
DTSTAMP:20260818T180951
CREATED:20180102T132915Z
LAST-MODIFIED:20180102T133149Z
UID:19578-1514851200-1517702399@ces.b2sg.org
SUMMARY:Postdoctoral Fellow
DESCRIPTION:Postdoc Positions Focusing on Gene Regulation in Cancer Progression \nMultiple postdoctoral positions are available in the laboratory of Dr. Jason Liu (http://molecularmedicine.uthscsa.edu/FAC_Research.aspx?facID=206) in the Department of Molecular Medicine at the University of Texas Health Science Center at San Antonio \nThe focus of the lab is studying enhancer function and epigenetic mechanism in gene regulation in cancer progression. Selected candidates will perform highly interdisciplinary and collaborative scientific research in one or more of the following projects\, working with human cell lines\, mouse models and clinical samples: \n(1) Explore the function of signaling-regulated enhancers in breast and prostate cancers\, and understand how enhancers are regulated by the crosstalk of different signaling pathways including sex hormones\, inflammation signals and metabolic signals; \n(2) Decipher the epigenetic and chromatin 3D level changes in enhancers upon developmental/pathological stimuli or during hormone/drug resistance acquisition; \n(3) Identify diagnostic/prognostic biomarkers and therapeutic targets for cancer and develop drugs for pre-clinical studies and potential clinical applications. \nOur research integrates next-generation sequencing (NGS)-based technologies and bioinformatics tools to investigate the component\, epigenetic\, and 3D level changes of enhancers in cancers \n(refer to Cell\, 2014 159: 358–373). We are efficiently combining biochemical\, cellular\, and animal model-related studies with different NGS-based assays. Our research program will help the trainees from both wet and dry lab sides to build up strong expertise and training record in molecular biology and multi-omics (genomics\, transcriptomics\, proteomics\, epigenomics and metabolomics). \nPositions require a Ph.D. degree (or equivalent) in biochemistry\, cell biology\, cancer biology\, bioinformatics\, or closely related biological sciences. The candidates need to have high motivation and strong molecular biology background. Any prior experience in patient-derived xenograft (PDX) models\, breast/prostate cancer\, and computational analyses will be valued. \nSan Antonio is one of the fastest growing cities. The UTHSCSA is the largest university of health science in South Texas and one of four medical schools in the UT System. The affiliated Cancer Therapy & Research Center (CTRC) is one of the NCI-designated national cancer centers in the state of Texas. A competitive salary and benefits package will be provided. \nTo apply: \nPlease send the application package in one single pdf file including a cover letter briefly describing your previous experience and your future research interest/plan\, curriculum vitae with list of publications\, and contact information of at least three references to the following email. You are also welcome to send any inquiries or questions you might have. \nContact information: \nDr. Jason Liu \nDepartment of Molecular Medicine \nThe University of Texas Health Science Center at San Antonio \n7703 Floyd Curl Drive \nSan Antonio\, TX\, 78229-3900 \nEmail: LiuZ7@uthscsa.edu
URL:https://ces.b2sg.org/event/uthscsa-2feb18/
LOCATION:UT Health Science Center in San Antonio\, 7703 Floyd Curl Drive\, San Antonio\, TX\, 78229\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180103
DTEND;VALUE=DATE:20180205
DTSTAMP:20260818T180951
CREATED:20180103T113456Z
LAST-MODIFIED:20180103T113456Z
UID:19584-1514937600-1517788799@ces.b2sg.org
SUMMARY:Postdoctoral Fellow
DESCRIPTION:A postdoctoral position is available to work at the interface of cancer epigenetics and translational therapeutics for head and neck malignancies. The position will be supported by a new NIH R01 award and industry-sponsored agreements in the Division of Head and Neck Surgery at the University of Pennsylvania Perelman School of Medicine. Our research program aims to develop novel approaches to target the tumor cell fractions within individual cancers that are innately resistant to current therapies. Studies will emphasize molecular and functional definition of the epigenetically distinct cell states within a heterogeneous tumor that contribute to treatment failure. Work will rely upon advanced in vitro cancer models\, patient-derived xenografts\, and human tumor specimens. Significant prior experience in epigenetics\, cancer biology\, bioinformatics\, stem cell biology\, and/or biochemistry is desirable. Training and career development will also be supported by investigators in a P01-funded program in esophageal squamous cell carcinoma in the Division of Gastroenterology. Applicants authorized for employment in the United States are strongly preferred. However visa sponsorship may be considered for an exceptional foreign applicant with well-developed English writing ability. Interested individuals should send cover letter\, CV\, and detailed reference information\, including most recent research supervisor\, by e-mail to: \nDevraj Basu\, M.D\, Ph.D.\, F.A.C.S.\nAssistant Professor \nDepartment of Otorhinolaryngology-Head and Neck Surgery \nThe University of Pennsylvania\n3600 Spruce St.\, 5 Ravdin/Silverstein \nPhiladelphia\, PA 19104 \nemail: devraj.basu@uphs.upenn.edu \nhttp://www.med.upenn.edu/apps/faculty/index.php/g275/p8137952
URL:https://ces.b2sg.org/event/upenn-3jan18/
LOCATION:University of Pennsylvania\, 3400 Civic Center Blvd\, Philadelphia\, 19104\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180103
DTEND;VALUE=DATE:20180205
DTSTAMP:20260818T180951
CREATED:20180103T114123Z
LAST-MODIFIED:20180103T114237Z
UID:19587-1514937600-1517788799@ces.b2sg.org
SUMMARY:Postdoctoral Associate
DESCRIPTION:A postdoctoral position is immediately available in the EpiCenter in the Department of Pediatrics at Baylor College of Medicine in Houston\, Texas. The research will focus on determining the molecular mechanisms underlying adverse pediatric outcomes. The successful candidate will employ integrative molecular epidemiologic methods for the assessments of adverse pediatric outcomes\, including structural birth defects and childhood cancer. The individual will work with genetic\, epigenetic\, and metabolomic data. The goal of this work will be to identify novel molecular predictors of adverse pediatric outcomes. The candidate will also be involved in the EpiCenter’s growing activities in global health. Successful candidates will be expected to tackle challenging scientific problems\, develop and optimize epidemiologic analytic pipelines\, and contribute to the positive and energetic work environment of the EpiCenter. \nRequired: \n\nPhD in Epidemiology
URL:https://ces.b2sg.org/event/baylor-3jan18/
LOCATION:Baylor College of Medicine\, 1 Baylor Plaza\, Houston\, TX\, 77030\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180103
DTEND;VALUE=DATE:20180205
DTSTAMP:20260818T180951
CREATED:20180103T115322Z
LAST-MODIFIED:20180103T115322Z
UID:19589-1514937600-1517788799@ces.b2sg.org
SUMMARY:Postdoc
DESCRIPTION:A postdoctoral position is immediately available within the Masri Lab at the University of California\, Irvine (UC Irvine). The Masri lab employs a systemic approach to understanding cancer metabolism that is linked to the circadian clock\, the biological pacemaker that regulates diurnal physiology. We are interested in two research questions. The first question relates to how genetic disruption of the circadian clock in mouse models alters tumorigenesis both at the level of initiation and disease progression. The second question is aimed at elucidating the systemic crosstalk between tumors and peripheral tissues and how cancer cells are able to rewire circadian metabolism at a distance.  \nWe are seeking independent and motivated postdoctoral candidates interested in a multi-disciplinary approach to tumorigenesis including: cancer metabolism\, circadian clock disruption\, and transcription and epigenetic control. The Masri lab utilizes genetic mouse models\, molecular and cell biology\, as well as genome-wide ‘omics’ approaches to determine changes in gene expression programs\, histone modifications\, and alterations in metabolites using metabolomics. In addition\, bioinformatics expertise is an advantage\, but certainly not required. Experience with mouse handling and experiments\, mammalian cell culture\, and routine molecular and cell biology are needed. Also\, at least 1 first author publication from the Ph.D. training period is required.  \nFor consideration\, applicants may send an email to Professor Selma Masri ( Masrilaboratory@gmail.com) with the following information:  \n\nBrief statement of research interests and future goals\nCV detailing research experience\, publications\, any fellowships obtained during the training period\, and other relevant information\nList of any manuscripts in preparation or currently under review\nNames of 3 references that are familiar with the research experience of the candidate and can provide letters of recommendation upon request
URL:https://ces.b2sg.org/event/ucirvine-3jan18/
LOCATION:UC Irvine\, Irvine\, CA\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180104
DTEND;VALUE=DATE:20180207
DTSTAMP:20260818T180951
CREATED:20180104T163049Z
LAST-MODIFIED:20180104T163049Z
UID:19594-1515024000-1517961599@ces.b2sg.org
SUMMARY:Scientist - Computational Biology
DESCRIPTION:Client Quanticel Research\, a drug division of Client Pharmaceuticals\, is committed to the development of breakthrough medicines for the treatment of cancer. Our proprietary platform for single-cell analysis of the cancer genome enables the discovery of first-in-class oncology therapeutics.  \nCQR seeks a scientist to join our vibrant interdisciplinary team to develop and facilitate interpretation of complex next-generation sequencing data from tumor xenografts and derived single-cells. The right candidate will share our passion for pioneering new solutions\, continual improvement\, and uncompromising quality in research.  \nResponsibilities will include\, but are not limited to\, the following:  \n\nAdapt open source tools and/or develop visualization methods to enable bench scientists to query\, display and interpret NGS data types. These include RNA-expression from single-cells and bulk tissues\, variant data from exome sequencing\, copy-number data from whole genome sequencing\, and epigenetic data.\nFacilitate data sharing/management from internal and open-source based databases.\nAbility to integrate laboratory instrument metadata to databases\n\nSkills/Knowledge Required: \n\nProficiency in shell scripting\, Django/Python\, R/Shiny\, SQL and JavaScript. Java considered a plus.\nComfortable working in Linux and Docker environments.\nGeneral knowledge of NGS technologies\, sequence analysis tools and public visualization resources.\nExperience with Amazon EC2 cloud resources; e.g. S3\, EC2\, Lambda and others.\nHighly self-motivated and enjoy working as part of a multi-disciplinary team\nOutstanding oral and written communication skills\n\nFunctional/Scientific/Technical Skills: \n\nAble to critically structure data.\nPossess in-depth knowledge in some area of data visualization\nUnderstands fundamental scientific problems and can apply knowledge to research and development projects and problems in a positive manner.\nContributes individually as well as on cross functional teams.\nResponsible for more complex assignments and for more than one project.
URL:https://ces.b2sg.org/event/advent-4jan18/
LOCATION:Advent Global Solutions\, San Francisco\, CA\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180104
DTEND;VALUE=DATE:20180207
DTSTAMP:20260818T180951
CREATED:20180104T163924Z
LAST-MODIFIED:20180104T164017Z
UID:19598-1515024000-1517961599@ces.b2sg.org
SUMMARY:Research Assistant
DESCRIPTION:The Wistar Institute has an opening for a Research Assistant in the laboratory of Dr. Rugang Zhang to perform research in which explores epigenetic approaches to ovarian cancer using tissue culture and patient-derived xenograft models.  \nThe candidate will work on a project sponsored by a pharmaceutical company to explore epigenetic therapy in ovarian cancer. The candidate will have ample opportunity to learn cutting-edge experimental techniques and clinically relevant preclinical ovarian cancer models. Duties include\, but are not limited to\, experiments in molecular biology\, cell biology\, tissue culture and mouse models of ovarian cancer.  \nBS/BA in biology or related field. Experience working in a lab is desirable but not required.  \nThe Wistar Institute is located in the University City area of Philadelphia\, in the heart of the University of Pennsylvania Campus. Wistar provides resources to its faculty and staff that enable them to conduct cutting edge collaborative research and provides for outstanding intellectual environments and state-of-the-art facilities. Research discoveries conducted at Wistar have led to the development of vaccines; the identification of genes associated with cancers; and the development of many other significant research technologies and tools. 
URL:https://ces.b2sg.org/event/wistar-4dec18/
LOCATION:Wistar Institute\, 3601 Spruce Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180114
DTEND;VALUE=DATE:20180216
DTSTAMP:20260818T180951
CREATED:20180114T105829Z
LAST-MODIFIED:20180114T105829Z
UID:19606-1515888000-1518739199@ces.b2sg.org
SUMMARY:Postdoctoral Scientist
DESCRIPTION:The Biochemistry and Molecular Medicine department is looking for a candidate that will work under the direct supervision of Dr. Mei-Yi Wu. He or she will be responsible for carrying out the research experiments. He or she will also participate in the weekly lab meeting\, and present and discuss the progress of the project with Dr. Mei-Yi Wu.  \nThe project focuses on two epigenetic modulators and members of the AT-rich interaction domain family\, ARID4A and ARID4B. Epigenetics plays an important role in human health and disease. Disruption of epigenetic modifications leads to dysregulation of gene function without altering the DNA sequence per se. A major challenge in understanding the importance of epigenetics in human health and diseases is to identify the specific epigenetic factors and the signaling involved. Currently\, we are investigating the role of ARID4A and ARID4B in development and cancer disease using state-of-the-art conditional knockout mouse models and genomic and proteomic approach. We also study the role of ARID4B in cancer stem cells that have been suggested as the major cause for therapy resistance and the driving force behind cancer metastasis and relapse. To investigate whether and how ARID4B drive cancer development\, we evalute the underlying molecular mechanisms by which ARID4B promotes therapy resistance and aggressive cancer.  \nDuties include: \n-Culture and transfection of mammial cells \n-Collecting samples for reporter gene assays \n-Western blooting to analyze protein expression \n-Cancer cell migration and invasion assays \n-Human cancer xenogrant experiments using SCID / NOD mice \n-The postdoc will also work with genetically modified mice \n-Ordering lab supplies\, lab maintenance and other duties as assigned \n-This position performs other duties as assigned. The omission of specific duties does not preclude the supervisor from assigning duties that are logically related to the position.  \nMinimum Qualifications: \nQualified candidates will hold a PhD in a related discipline. Degree must be conferred by the start date of the position  \nAdditional Required Licenses/Certifications/Posting Specific Minimum Qualifications:  \nPreferred Qualifications: \nPh.D. degree\, with experience in molecular and cellular biology. 
URL:https://ces.b2sg.org/event/gwu-14jan18/
LOCATION:George Washington University\, 2121 I St NW\, Washington\, DC\, 20052\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180114
DTEND;VALUE=DATE:20180216
DTSTAMP:20260818T180951
CREATED:20180114T110932Z
LAST-MODIFIED:20180114T111008Z
UID:19608-1515888000-1518739199@ces.b2sg.org
SUMMARY:Research Scientist
DESCRIPTION:RESEARCH SCIENTIST\, Koch Institute (KI) for Integrative Cancer Research-J&J Lung Cancer Initiative Collaboration (multiple positions)\, to contribute to three KI laboratories involved in research regarding the discovery and development of therapeutics and diagnostics that may be useful treating\, preventing\, intercepting\, and/or diagnosing diseases specifically focused on lung cancer. The Jacks Laboratory will focus on genetic and epigenetic changes accompanying and controlling lung cancer initiation and progression; developing vaccines for disease interception; and the role of inflammation\, inflammatory cells\, and specific inflammatory mediators in lung cancer development. The Bhatia Laboratory will focus on novel diagnostic and early detection technologies\, including protease activity-based nanosensors and explore the utility of these technologies using human genomic data and genetically-engineered mouse models (GEMMs) of lung cancer to detect and stratify disease early enough for interception. The Irvine laboratory will focus on early interception using immunotherapy agents to detect and prophylactically protect from lung cancer and generate novel immune-based drugs and vaccine platforms\, especially focused on Kras-mutant lung tumors. These will be tested initially in GEMM models. Will contribute to executing research aims; establishing research strategy; reporting; and planning and writing animal and other protocols\, manuscripts\, and reports.  \nJob Requirements: \nREQUIRED: MD and/or Ph.D. in medicine and/or biomedical science; extensive knowledge of cancer biology and related fields; ability to conceptualize and write proposals and publishable manuscripts\, evaluate and train junior researchers\, innovate\, and conduct research; meticulous attention to detail; strong organizational\, documentation\, interpersonal\, and communication skills; comfort summarizing and reporting results; ability to work collaboratively\, follow safety procedures\, and maintain a safe work environment. Familiarity with physiology; cell and molecular biology; immunology; animal testing of biologics; materials science; and/or histological\, biochemical\, and mechanical analyses ideal. Job #15547  \nThis is a one-year\, term-limit appointment with an extension based on continued funding.
URL:https://ces.b2sg.org/event/mit-14jan18/
LOCATION:Koch Institute MIT\, Cambridge\, MA\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180114
DTEND;VALUE=DATE:20180216
DTSTAMP:20260818T180951
CREATED:20180114T153848Z
LAST-MODIFIED:20180114T153910Z
UID:19614-1515888000-1518739199@ces.b2sg.org
SUMMARY:Postdoctoral Associate
DESCRIPTION:Applications are invited from ambitious\, independent and motivated candidates to work with Professor Peter D. Adams to investigate the epigenetics of aging and cancer at Sanford Burnham Prebys Medical Discovery Institute\, San Diego. Specific projects in the lab range from development of novel epigenetic therapies to combat cancer (for example\, epigenetic therapies to synergize with immune therapies)\, to investigation of epigenetic mechanisms that contribute to age-associated increase in cancer. A long-term goal of the lab is to develop epigenetic-based approaches for cancer chemoprevention.  \nThe project will employ state-of-the-art molecular and cellular biology approaches\, including ChIP-seq\, RNA-seq\, ATAC-seq\, DNA methyl-seq and other large-scale epigenomic and chromatin analyses\, including at the single-cell level; high throughput chemical and RNAi/CRISPR phenotypic screens; cell imaging; state-of-the-art gene manipulations using RNAi and CRISPR technology. In addition\, we routinely employ sophisticated mouse models and human tissues.  \nThe lab strives to be highly collaborative with other labs in San Diego\, the US and elsewhere\, for example collaborating with computational biologists\, immunologists\, experts in specific mouse models of cancer and aging\, and surgeons\, pathologists and clinical oncologists. San Diego is an outstanding scientific environment and a fabulous place to live.  \nRequired Skills  \nRequired Experience  \nCandidates should have\, or be working towards\, a PhD or equivalent degree in a biological science. Expertise in an aspect of cell and/or molecular biology and/or animal models is essential. The lab has dedicated computational biology support for data analysis\, so computational expertise is an advantage\, but not essential. Successful applicants will be able to learn computational approaches for analysis of large datasets\, a big advantage in a competitive job market.  \nInterested candidates should submit one PDF with a summary of achievements and research interests\, updated CV and contact information for 3 letters of references.  \nLab website: https://chromatin.wordpress.com 
URL:https://ces.b2sg.org/event/sbp-14jan18/
LOCATION:Sanford Burnham Prebys Medical Discovery Institute\, 10901 N Torrey Pines Rd\, La Jolla\, CA\, 92037\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/06/sanford-burham-sbp.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180119
DTEND;VALUE=DATE:20180221
DTSTAMP:20260818T180951
CREATED:20180119T214721Z
LAST-MODIFIED:20180119T215022Z
UID:19620-1516320000-1519171199@ces.b2sg.org
SUMMARY:Intern - Molecular Oncology
DESCRIPTION:Start Date: Summer 2018  \nLength of Assignment: 12 weeks  \nThe mission of the Molecular Oncology department is to bring lasting benefit and cures to cancer patients through innovative scientific discoveries and medicines.  \n\nWe will transform cancer care by taking a science-driven approach to drug discovery and development to achieve enduring clinical benefit.\nGuided by a deep understanding of the unique molecular features associated with each patient’s disease\, we will identify and understand pathways that drive cancer and establish the therapeutic potential of individual targets.\nBy combining laboratory and clinical investigation\, we will design strategies and medicines that target tumor cells\, drug resistance\, and the tumor microenvironment to achieve dramatic\, lasting\, benefit for cancer patients.\n\nPosition 1  \nThis intern will work with a postdoctoral fellow to investigate the impact of a kinase on the interaction between CD8 T cells and Antigen Presenting Cells (APC). He or she will use FACS analysis and various imaging techniques to investigate the above question.  \nPosition 2  \n\nGenerate and test mammalian cells edited by CRISPR technology.\nPerform various assays including western blotting\, qPCR\, ELISA\, FACS to determine changes in gene expression.\nOptimize culture conditions for primary cells and conduct in vitro phagocytosis assay.\n\nPosition 3 \nMetastases are the principal cause of death in patients with colorectal cancer (CRC). In order to develop effective methods for prevention and targeting of metastatic disease\, it is of crucial importance to better understand the cellular and molecular mechanisms regulating the metastatic cascade. The project will consist in evaluating the role of specific regulatory regions and signaling pathways in mediating the metastatic ability of colon cancer cells. First\, the intern will have to design\, clone and validate CRISPR-based tools (CRISPR KO or CRISPR i) to specifically and efficiently target genes and regulatory regions found in our in vivo screening and thought to be playing a key role in colon cancer cells metastatic ability. Also\, the intern will be involved in setting up a drug screening in order to assess the effect of different compounds on colon cancer cells in vitro. \nWho You Are  \nPosition 1  \n\nPreferred degree level: PhD\nPreferred majors are: Immunology\, Cell Biology.\nLab skills needed: FACS\, Immunofluorescence staining\, Cell Culture\, Fluorescence Microscopy\n\nPosition 2  \n\nPreferred degree level: BS\, MS\, or PhD\nMajors: Molecular Biology\, Cell Biology\, Immunology\nLab skills: mammalian cell culture\, cell transfection\, DNA/RNA preparation\, PCR\, FACS\n\nPosition 3  \n\nPreferred degree level: MS or PhD\nBackground in Molecular Biology\, Cell Biology\, Genetics\, Biochemistry\nPrevious experience with cell culture and molecular biology techniques (cloning\, digestion\, DNA preparation…) is highly desired\nPrevious experience with flow cytometry analysis and/or imaging techniques (confocal microscopy…) is preferred\nApplicants with good understanding of concepts in cancer biology/genomics/epigenetics will be prioritized
URL:https://ces.b2sg.org/event/genentech-19jan18/
LOCATION:Genentech\, 1 DNA Way\, South San Francisco\, CA\, 94080\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/05/genentech-logo.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180130
DTEND;VALUE=DATE:20180304
DTSTAMP:20260818T180951
CREATED:20180130T142854Z
LAST-MODIFIED:20180224T062119Z
UID:19628-1517270400-1520121599@ces.b2sg.org
SUMMARY:Postdoctoral Fellow
DESCRIPTION:The Faber laboratory has an opening for a postdoctoral fellow to study the rational combinations of epigenetic drugs for solid tumor therapies. The successful candidate will have a Ph.D. and a strong background in cancer biology. \nJob Type: Full-time \nRequired experience: \n\ncancer biology: 4 years
URL:https://ces.b2sg.org/event/vcu-30jan18/
LOCATION:Virginia Commonwealth University\, 907 Floyd Ave\, Richmond\, VA\, 23284\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/09/VCU-virginia-commonwealth-e1506279590219.jpg
END:VEVENT
END:VCALENDAR