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X-WR-CALNAME:Cancer Epigenetics Society
X-ORIGINAL-URL:https://ces.b2sg.org
X-WR-CALDESC:Events for Cancer Epigenetics Society
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DTSTART:20170326T010000
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DTSTART:20171029T010000
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DTSTART:20180325T010000
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DTSTART;VALUE=DATE:20171231
DTEND;VALUE=DATE:20180301
DTSTAMP:20260818T220907
CREATED:20171231T113056Z
LAST-MODIFIED:20171231T113056Z
UID:19564-1514678400-1519862399@ces.b2sg.org
SUMMARY:Assistant/Associate Professor
DESCRIPTION:The Department of Pathology and Laboratory Medicine at the Perelman School of Medicine at the University of Pennsylvania seeks candidates for an Associate or Assistant Professor position in the tenure track. The successful applicant will have experience in the field of Genome Editing & Functional Cancer Genomics and will creatively leverage the CRISPR/Cas9 or similar technologies towards functional characterization of chromosomal translocations\, candidate drive mutations\, epigenetic alterations\, genetic polymorphisms\, etc. Identification of new susceptibility alleles in important pediatric cancers and related diseases is also a priority. Responsibilities include establishing and maintaining an independent\, extramurally funded research program. Teaching and mentoring of graduate and medical students is an integral component of this position. Applicants must have an M.D./Ph.D or equivalent degree and have demonstrated excellent qualifications in research and education. \nThe position is affiliated with the Division of Cancer Pathobiology & the Center for Childhood Cancer Research at the Children’s Hospital of Philadelphia (CHOP). The Division & CCCR are housed in the state-of-the-art Colket Translational Research Building. More information about the program can be found at: http://www.chop.edu/cccr/research-topic/cancer-pathobiology-research 
URL:https://ces.b2sg.org/event/upenn-31dec17/
LOCATION:University of Pennsylvania\, 3400 Civic Center Blvd\, Philadelphia\, 19104\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/05/penn-1-e1494306554396.jpg
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180104
DTEND;VALUE=DATE:20180207
DTSTAMP:20260818T220907
CREATED:20180104T163049Z
LAST-MODIFIED:20180104T163049Z
UID:19594-1515024000-1517961599@ces.b2sg.org
SUMMARY:Scientist - Computational Biology
DESCRIPTION:Client Quanticel Research\, a drug division of Client Pharmaceuticals\, is committed to the development of breakthrough medicines for the treatment of cancer. Our proprietary platform for single-cell analysis of the cancer genome enables the discovery of first-in-class oncology therapeutics.  \nCQR seeks a scientist to join our vibrant interdisciplinary team to develop and facilitate interpretation of complex next-generation sequencing data from tumor xenografts and derived single-cells. The right candidate will share our passion for pioneering new solutions\, continual improvement\, and uncompromising quality in research.  \nResponsibilities will include\, but are not limited to\, the following:  \n\nAdapt open source tools and/or develop visualization methods to enable bench scientists to query\, display and interpret NGS data types. These include RNA-expression from single-cells and bulk tissues\, variant data from exome sequencing\, copy-number data from whole genome sequencing\, and epigenetic data.\nFacilitate data sharing/management from internal and open-source based databases.\nAbility to integrate laboratory instrument metadata to databases\n\nSkills/Knowledge Required: \n\nProficiency in shell scripting\, Django/Python\, R/Shiny\, SQL and JavaScript. Java considered a plus.\nComfortable working in Linux and Docker environments.\nGeneral knowledge of NGS technologies\, sequence analysis tools and public visualization resources.\nExperience with Amazon EC2 cloud resources; e.g. S3\, EC2\, Lambda and others.\nHighly self-motivated and enjoy working as part of a multi-disciplinary team\nOutstanding oral and written communication skills\n\nFunctional/Scientific/Technical Skills: \n\nAble to critically structure data.\nPossess in-depth knowledge in some area of data visualization\nUnderstands fundamental scientific problems and can apply knowledge to research and development projects and problems in a positive manner.\nContributes individually as well as on cross functional teams.\nResponsible for more complex assignments and for more than one project.
URL:https://ces.b2sg.org/event/advent-4jan18/
LOCATION:Advent Global Solutions\, San Francisco\, CA\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180104
DTEND;VALUE=DATE:20180207
DTSTAMP:20260818T220907
CREATED:20180104T163924Z
LAST-MODIFIED:20180104T164017Z
UID:19598-1515024000-1517961599@ces.b2sg.org
SUMMARY:Research Assistant
DESCRIPTION:The Wistar Institute has an opening for a Research Assistant in the laboratory of Dr. Rugang Zhang to perform research in which explores epigenetic approaches to ovarian cancer using tissue culture and patient-derived xenograft models.  \nThe candidate will work on a project sponsored by a pharmaceutical company to explore epigenetic therapy in ovarian cancer. The candidate will have ample opportunity to learn cutting-edge experimental techniques and clinically relevant preclinical ovarian cancer models. Duties include\, but are not limited to\, experiments in molecular biology\, cell biology\, tissue culture and mouse models of ovarian cancer.  \nBS/BA in biology or related field. Experience working in a lab is desirable but not required.  \nThe Wistar Institute is located in the University City area of Philadelphia\, in the heart of the University of Pennsylvania Campus. Wistar provides resources to its faculty and staff that enable them to conduct cutting edge collaborative research and provides for outstanding intellectual environments and state-of-the-art facilities. Research discoveries conducted at Wistar have led to the development of vaccines; the identification of genes associated with cancers; and the development of many other significant research technologies and tools. 
URL:https://ces.b2sg.org/event/wistar-4dec18/
LOCATION:Wistar Institute\, 3601 Spruce Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/png:https://ces.b2sg.org/wp-content/uploads/2017/07/wistar-inst.png
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180114
DTEND;VALUE=DATE:20180216
DTSTAMP:20260818T220907
CREATED:20180114T105829Z
LAST-MODIFIED:20180114T105829Z
UID:19606-1515888000-1518739199@ces.b2sg.org
SUMMARY:Postdoctoral Scientist
DESCRIPTION:The Biochemistry and Molecular Medicine department is looking for a candidate that will work under the direct supervision of Dr. Mei-Yi Wu. He or she will be responsible for carrying out the research experiments. He or she will also participate in the weekly lab meeting\, and present and discuss the progress of the project with Dr. Mei-Yi Wu.  \nThe project focuses on two epigenetic modulators and members of the AT-rich interaction domain family\, ARID4A and ARID4B. Epigenetics plays an important role in human health and disease. Disruption of epigenetic modifications leads to dysregulation of gene function without altering the DNA sequence per se. A major challenge in understanding the importance of epigenetics in human health and diseases is to identify the specific epigenetic factors and the signaling involved. Currently\, we are investigating the role of ARID4A and ARID4B in development and cancer disease using state-of-the-art conditional knockout mouse models and genomic and proteomic approach. We also study the role of ARID4B in cancer stem cells that have been suggested as the major cause for therapy resistance and the driving force behind cancer metastasis and relapse. To investigate whether and how ARID4B drive cancer development\, we evalute the underlying molecular mechanisms by which ARID4B promotes therapy resistance and aggressive cancer.  \nDuties include: \n-Culture and transfection of mammial cells \n-Collecting samples for reporter gene assays \n-Western blooting to analyze protein expression \n-Cancer cell migration and invasion assays \n-Human cancer xenogrant experiments using SCID / NOD mice \n-The postdoc will also work with genetically modified mice \n-Ordering lab supplies\, lab maintenance and other duties as assigned \n-This position performs other duties as assigned. The omission of specific duties does not preclude the supervisor from assigning duties that are logically related to the position.  \nMinimum Qualifications: \nQualified candidates will hold a PhD in a related discipline. Degree must be conferred by the start date of the position  \nAdditional Required Licenses/Certifications/Posting Specific Minimum Qualifications:  \nPreferred Qualifications: \nPh.D. degree\, with experience in molecular and cellular biology. 
URL:https://ces.b2sg.org/event/gwu-14jan18/
LOCATION:George Washington University\, 2121 I St NW\, Washington\, DC\, 20052\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/05/gwu-1.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180114
DTEND;VALUE=DATE:20180216
DTSTAMP:20260818T220907
CREATED:20180114T110932Z
LAST-MODIFIED:20180114T111008Z
UID:19608-1515888000-1518739199@ces.b2sg.org
SUMMARY:Research Scientist
DESCRIPTION:RESEARCH SCIENTIST\, Koch Institute (KI) for Integrative Cancer Research-J&J Lung Cancer Initiative Collaboration (multiple positions)\, to contribute to three KI laboratories involved in research regarding the discovery and development of therapeutics and diagnostics that may be useful treating\, preventing\, intercepting\, and/or diagnosing diseases specifically focused on lung cancer. The Jacks Laboratory will focus on genetic and epigenetic changes accompanying and controlling lung cancer initiation and progression; developing vaccines for disease interception; and the role of inflammation\, inflammatory cells\, and specific inflammatory mediators in lung cancer development. The Bhatia Laboratory will focus on novel diagnostic and early detection technologies\, including protease activity-based nanosensors and explore the utility of these technologies using human genomic data and genetically-engineered mouse models (GEMMs) of lung cancer to detect and stratify disease early enough for interception. The Irvine laboratory will focus on early interception using immunotherapy agents to detect and prophylactically protect from lung cancer and generate novel immune-based drugs and vaccine platforms\, especially focused on Kras-mutant lung tumors. These will be tested initially in GEMM models. Will contribute to executing research aims; establishing research strategy; reporting; and planning and writing animal and other protocols\, manuscripts\, and reports.  \nJob Requirements: \nREQUIRED: MD and/or Ph.D. in medicine and/or biomedical science; extensive knowledge of cancer biology and related fields; ability to conceptualize and write proposals and publishable manuscripts\, evaluate and train junior researchers\, innovate\, and conduct research; meticulous attention to detail; strong organizational\, documentation\, interpersonal\, and communication skills; comfort summarizing and reporting results; ability to work collaboratively\, follow safety procedures\, and maintain a safe work environment. Familiarity with physiology; cell and molecular biology; immunology; animal testing of biologics; materials science; and/or histological\, biochemical\, and mechanical analyses ideal. Job #15547  \nThis is a one-year\, term-limit appointment with an extension based on continued funding.
URL:https://ces.b2sg.org/event/mit-14jan18/
LOCATION:Koch Institute MIT\, Cambridge\, MA\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2018/01/Koch-mit-e1515928148181.jpg
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180114
DTEND;VALUE=DATE:20180216
DTSTAMP:20260818T220907
CREATED:20180114T153848Z
LAST-MODIFIED:20180114T153910Z
UID:19614-1515888000-1518739199@ces.b2sg.org
SUMMARY:Postdoctoral Associate
DESCRIPTION:Applications are invited from ambitious\, independent and motivated candidates to work with Professor Peter D. Adams to investigate the epigenetics of aging and cancer at Sanford Burnham Prebys Medical Discovery Institute\, San Diego. Specific projects in the lab range from development of novel epigenetic therapies to combat cancer (for example\, epigenetic therapies to synergize with immune therapies)\, to investigation of epigenetic mechanisms that contribute to age-associated increase in cancer. A long-term goal of the lab is to develop epigenetic-based approaches for cancer chemoprevention.  \nThe project will employ state-of-the-art molecular and cellular biology approaches\, including ChIP-seq\, RNA-seq\, ATAC-seq\, DNA methyl-seq and other large-scale epigenomic and chromatin analyses\, including at the single-cell level; high throughput chemical and RNAi/CRISPR phenotypic screens; cell imaging; state-of-the-art gene manipulations using RNAi and CRISPR technology. In addition\, we routinely employ sophisticated mouse models and human tissues.  \nThe lab strives to be highly collaborative with other labs in San Diego\, the US and elsewhere\, for example collaborating with computational biologists\, immunologists\, experts in specific mouse models of cancer and aging\, and surgeons\, pathologists and clinical oncologists. San Diego is an outstanding scientific environment and a fabulous place to live.  \nRequired Skills  \nRequired Experience  \nCandidates should have\, or be working towards\, a PhD or equivalent degree in a biological science. Expertise in an aspect of cell and/or molecular biology and/or animal models is essential. The lab has dedicated computational biology support for data analysis\, so computational expertise is an advantage\, but not essential. Successful applicants will be able to learn computational approaches for analysis of large datasets\, a big advantage in a competitive job market.  \nInterested candidates should submit one PDF with a summary of achievements and research interests\, updated CV and contact information for 3 letters of references.  \nLab website: https://chromatin.wordpress.com 
URL:https://ces.b2sg.org/event/sbp-14jan18/
LOCATION:Sanford Burnham Prebys Medical Discovery Institute\, 10901 N Torrey Pines Rd\, La Jolla\, CA\, 92037\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180119
DTEND;VALUE=DATE:20180221
DTSTAMP:20260818T220907
CREATED:20180119T214721Z
LAST-MODIFIED:20180119T215022Z
UID:19620-1516320000-1519171199@ces.b2sg.org
SUMMARY:Intern - Molecular Oncology
DESCRIPTION:Start Date: Summer 2018  \nLength of Assignment: 12 weeks  \nThe mission of the Molecular Oncology department is to bring lasting benefit and cures to cancer patients through innovative scientific discoveries and medicines.  \n\nWe will transform cancer care by taking a science-driven approach to drug discovery and development to achieve enduring clinical benefit.\nGuided by a deep understanding of the unique molecular features associated with each patient’s disease\, we will identify and understand pathways that drive cancer and establish the therapeutic potential of individual targets.\nBy combining laboratory and clinical investigation\, we will design strategies and medicines that target tumor cells\, drug resistance\, and the tumor microenvironment to achieve dramatic\, lasting\, benefit for cancer patients.\n\nPosition 1  \nThis intern will work with a postdoctoral fellow to investigate the impact of a kinase on the interaction between CD8 T cells and Antigen Presenting Cells (APC). He or she will use FACS analysis and various imaging techniques to investigate the above question.  \nPosition 2  \n\nGenerate and test mammalian cells edited by CRISPR technology.\nPerform various assays including western blotting\, qPCR\, ELISA\, FACS to determine changes in gene expression.\nOptimize culture conditions for primary cells and conduct in vitro phagocytosis assay.\n\nPosition 3 \nMetastases are the principal cause of death in patients with colorectal cancer (CRC). In order to develop effective methods for prevention and targeting of metastatic disease\, it is of crucial importance to better understand the cellular and molecular mechanisms regulating the metastatic cascade. The project will consist in evaluating the role of specific regulatory regions and signaling pathways in mediating the metastatic ability of colon cancer cells. First\, the intern will have to design\, clone and validate CRISPR-based tools (CRISPR KO or CRISPR i) to specifically and efficiently target genes and regulatory regions found in our in vivo screening and thought to be playing a key role in colon cancer cells metastatic ability. Also\, the intern will be involved in setting up a drug screening in order to assess the effect of different compounds on colon cancer cells in vitro. \nWho You Are  \nPosition 1  \n\nPreferred degree level: PhD\nPreferred majors are: Immunology\, Cell Biology.\nLab skills needed: FACS\, Immunofluorescence staining\, Cell Culture\, Fluorescence Microscopy\n\nPosition 2  \n\nPreferred degree level: BS\, MS\, or PhD\nMajors: Molecular Biology\, Cell Biology\, Immunology\nLab skills: mammalian cell culture\, cell transfection\, DNA/RNA preparation\, PCR\, FACS\n\nPosition 3  \n\nPreferred degree level: MS or PhD\nBackground in Molecular Biology\, Cell Biology\, Genetics\, Biochemistry\nPrevious experience with cell culture and molecular biology techniques (cloning\, digestion\, DNA preparation…) is highly desired\nPrevious experience with flow cytometry analysis and/or imaging techniques (confocal microscopy…) is preferred\nApplicants with good understanding of concepts in cancer biology/genomics/epigenetics will be prioritized
URL:https://ces.b2sg.org/event/genentech-19jan18/
LOCATION:Genentech\, 1 DNA Way\, South San Francisco\, CA\, 94080\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/05/genentech-logo.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180130
DTEND;VALUE=DATE:20180304
DTSTAMP:20260818T220907
CREATED:20180130T142854Z
LAST-MODIFIED:20180224T062119Z
UID:19628-1517270400-1520121599@ces.b2sg.org
SUMMARY:Postdoctoral Fellow
DESCRIPTION:The Faber laboratory has an opening for a postdoctoral fellow to study the rational combinations of epigenetic drugs for solid tumor therapies. The successful candidate will have a Ph.D. and a strong background in cancer biology. \nJob Type: Full-time \nRequired experience: \n\ncancer biology: 4 years
URL:https://ces.b2sg.org/event/vcu-30jan18/
LOCATION:Virginia Commonwealth University\, 907 Floyd Ave\, Richmond\, VA\, 23284\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/09/VCU-virginia-commonwealth-e1506279590219.jpg
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