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PRODID:-//Cancer Epigenetics Society - ECPv5.3.2.1//NONSGML v1.0//EN
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METHOD:PUBLISH
X-WR-CALNAME:Cancer Epigenetics Society
X-ORIGINAL-URL:https://ces.b2sg.org
X-WR-CALDESC:Events for Cancer Epigenetics Society
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TZID:Europe/Paris
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TZOFFSETFROM:+0100
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TZNAME:CEST
DTSTART:20180325T010000
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DTSTART:20181028T010000
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180208
DTEND;VALUE=DATE:20180310
DTSTAMP:20260820T011935
CREATED:20180208T203038Z
LAST-MODIFIED:20180208T203038Z
UID:19650-1518048000-1520639999@ces.b2sg.org
SUMMARY:Research Assistant
DESCRIPTION:GW’s Department of Microbiology\, Immunology\, and Tropical Medicine is searching for a full-time Research Assistant for Dr.Chiappinelli’s laboratory at the George Washington Cancer Center (https://smhs.gwu.edu/cancercenter/) and the Department of Microbiology\, Immunology\, & Tropical Medicine. Dr. Chiappinelli’s laboratory focuses on the epigenetic control of gene expression in cancer\, specifically of immune signaling in and from tumor cells. Our goal is to use epigenetic therapies to harness the power of the immune system to fight cancer.  \nThe Research Assistant will be responsible for performing experiments under the direction of the principal investigator in a biomedical research laboratory and contributing to general maintenance of the laboratory\, equipment and supplies. The individual will conduct experiments under the direct supervision of a postdoctoral fellow and will also receive mentoring and direct guidance from Dr. Chiappinelli in order to advance his/her career in academic research.  \nResponsibilities include: \n\nProvide assistance to research scientist\, postdoctoral scientists and lab manager\nOptimize\, develop\, qualify and execute the following assays: basic tissue culture\, PCR \, quantitative RT- PCR \, western blots\, and flow cytometry.\nGeneral maintenance of the laboratory. Maintain Good Laboratory Practice\, comply with biosafety guidelines\, keep inspection records and generate SOPs and reports.\nMaintain and troubleshoot equipment\nWork closely with graduate students\nParticipate in group meetings and present data\nOther duties as assigned. The omission of specific duties does not preclude the supervisor from assigning duties that are logically related to the position.\n\nIncumbent is expected to work well as part of a team and have enthusiasm for the practice of science.  \nMinimum Qualifications:\nQualified candidates will hold a BA/BS in a related discipline. Degree must be conferred by the start date of the position.  \nAdditional Required Licenses/Certifications/Posting Specific Minimum Qualifications:  \nPreferred Qualifications:\nEducation: Bachelor’s degree in biology\, chemistry\, or related field.  \nExperience: Previous laboratory experience (during undergraduate education or post-undergraduate).  \nPreferred qualifications include: experience handling laboratory animals\, experience in immunology-based and molecular biology techniques including flow cytometry\, quantitative RT- PCR \, nucleic acid extractions\, cell culture\, and aseptic technique. 
URL:https://ces.b2sg.org/event/gwu-8feb18/
LOCATION:George Washington University\, 2121 I St NW\, Washington\, DC\, 20052\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180208
DTEND;VALUE=DATE:20180310
DTSTAMP:20260820T011935
CREATED:20180208T204543Z
LAST-MODIFIED:20180208T204911Z
UID:19655-1518048000-1520639999@ces.b2sg.org
SUMMARY:Postdoctoral Fellow
DESCRIPTION:The Simone Laboratory in the Radiation Oncology Department at Thomas Jefferson University Hospital in Philadelphia\, PA is seeking an outstanding post-doctoral fellow to work in the area of cancer and radiation biology. Our laboratory focuses on using metabolic manipulation such as dietary alterations\, to improve standard cancer therapy such as radiation and chemotherapy. Mechanistically\, our focus is on microRNA alterations and downstream effectors. Our laboratory has a focus on hormonally responsive cancers such as breast and prostate cancer using both in vitro and in vivo models. From the pre-clinical data generated in the Simone Laboratory\, we have now opened multiple clinical trials with hormone-driven cancer patients which allows for the laboratory to evaluate translational endpoints of our basic science research. \nExperience Required : The candidate must be highly motivated\, independent and interested in our projects. The candidate must have PhD in molecular biology\, cell biology or a cancer related field. Although not absolutely necessary\, the ideal candidate will preferably have some experience with caloric restriction\, epigenetics\, microRNA or radiation biology. Expertise in microarray analysis\, RT-PCR\, ChIP\, cloning\, mouse husbandry\, in vivo tumor experiments are also a plus. The successful candidate will of course have mentoring so that career goals can be achieved\, but must be able to independently generate hypotheses\, design experiments to test the hypothesis\, performs routine and more difficult procedures\, analyze data and coherently present results in the form of presentations\, abstracts\, manuscripts and the basis for grant writing\, preparation and submission. In addition\, qualified candidates should have strong verbal and written communication skills\, and a demonstrated record of scientific achievement through peer-reviewed publications. Successful\, well-motivated candidates will join a highly interactive\, interdisciplinary team of researchers with diverse backgrounds and expertise in a collaborative scientific environment. Preference will be given to individuals with these skill sets who are now completing their thesis work and have at least one high-impact publication.
URL:https://ces.b2sg.org/event/tju-8feb18/
LOCATION:Thomas Jefferson University Hospital\, Philadelphia\, PA\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180208
DTEND;VALUE=DATE:20180310
DTSTAMP:20260820T011935
CREATED:20180208T211115Z
LAST-MODIFIED:20180208T215042Z
UID:19661-1518048000-1520639999@ces.b2sg.org
SUMMARY:Research Fellow
DESCRIPTION:Postdoctoral position is available in Prof. Jolanta Grembecka laboratory\, University of Michigan\, Ann Arbor\, to carry out an interdisciplinary project to study the effect of small molecules in in vitro and in vivo models of cancers and to pursue target validation studies using genetic approaches. We are seeking for a highly motivated postdoctoral fellow with extensive experience in cancer cell biology. The research will be focused on evaluation of the activity and the mechanism of action of novel small molecules blocking epigenetic proteins in cancer. This position requires the expertise in cell biology and molecular biology techniques\, including PCR\, qRT-PCR\, Western Blotting\, co-Immunoprecipitation\, ChIP\, ChIPSeq\, flow cytometry\, fluorescence microscopy\, immunostaining. Prior work experience with animals such as transgenic mice and xenograft models of cancer would be desired. Successful candidate will be a part of an interdisciplinary team focused on development and pre-clinical evaluation of novel anti-cancer drug candidates. Required Qualifications* \nApplicant must have PhD in biology or related field. The candidates must be a first author on at least 2-3 publications. This position requires extensive experience in cell and molecular biology techniques. Furthermore\, excellent oral and written communication skills in English are required as well as the ability to conduct independent scientific investigations.
URL:https://ces.b2sg.org/event/umich-8feb18/
LOCATION:University of Michigan\, 500 S State St\, Ann Arbor\, MI\, 48109\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180209
DTEND;VALUE=DATE:20180310
DTSTAMP:20260820T011935
CREATED:20180209T002613Z
LAST-MODIFIED:20180209T003129Z
UID:19669-1518134400-1520639999@ces.b2sg.org
SUMMARY:Postdoctoral Fellow
DESCRIPTION:  \nAccording to the National Institute of Health (NIH) and the National Science Foundation (NSF)\, a postdoc is an individual who has received a doctoral degree (or equivalent) and is engaged in a temporary and defined period of mentored advanced research training to enhance the professional skills and research independence needed to pursue his or her chosen career path. In addition\, according to the National Postdoc Association (NPA)\, Postdoctoral appointees can pursue basic\, clinical or translational projects so long as their primary effort is devoted toward their own scholarship. Postdocs are essential to the scholarly mission of the mentor and host institution\, and thus are expected to have the freedom to publish the results of their scholarship. \nCharacteristics of a postdoctoral appointment:  \nIt is expected that postdocs at MCW\, with the assistance of their supervisor\, will: \n\nTransition to career independence through the development of professional skills that enable the postdoc to actively pursue a career of his/her own choosing.\nBe supervised by at least one senior scholar who actively promotes the postdoc’s professional development.\nEstablish an individual development plan (IDP) that incorporates equally the postdoc’s career and training goals and the mentor’s research goals.\nPursue basic\, clinical\, or translational projects so long as effort is focused primarily on research.\nPublish results of the postdoc’s research and scholarship during their appointment.\nThe postdoctoral appointment is temporary by nature\, the aggregate amount of time spent as a postdoc is recommended to not exceed five years (not including family medical leave or maternity/paternity leave).\nAs postdocs are important members of the host institution’s community\, appropriate levels of compensation\, health care\, and other benefits commensurate with their essential status should be afforded\, independent of the postdoc’s source of funding.\n\n\nPrimary Functions \n \n\nPlan\, design and execute complex research studies\, procedures and protocols.\nParticipate in discovery projects.\nCoordinate research study activities; lead and manage projects.\nOversee organization\, synthesis and analysis of data and findings.\nPrepare scientific reports\, outcome findings and scientific manuscripts.\nParticipate in meetings with principle investigator and research staff in which you will evaluate/interpret the validity of data\, develop methodologies\, and design and evaluate lab procedures.\nMaintain supplies\, may require negotiation with vendors\, and track purchase orders.\nMay oversee the work of laboratory personnel including training and development as well as daily work direction\, delegation and establishing priorities.\n\n\nKnowledge – Skills – Abilities  \nRequired knowledge: biology\, chemistry\, mathematics\, statistics\, documentation\, records management\, data utilization\, complex problem solving\, critical thinking\, resource management\, and writing skills \nSkills and abilities: Necessary research skills include standard molecular and cellular biology techniques. Qualified candidates should have outstanding critical thinking and problem-solving skills\, excellent written and oral skills\, as well as the ability to collaborate with others in a team-oriented environment. Experience in epigenetics and/or mouse models\, especially cancer-related\, would be an asset.
URL:https://ces.b2sg.org/event/mcw-8feb18/
LOCATION:Medical College of Wisconsin\, Milwaukee\, WI\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180224
DTEND;VALUE=DATE:20180325
DTSTAMP:20260820T011935
CREATED:20180224T063337Z
LAST-MODIFIED:20180224T063413Z
UID:19678-1519430400-1521935999@ces.b2sg.org
SUMMARY:Postdoctoral Research Associate
DESCRIPTION:Preferred Education: \nPh.D. Biology\, Biochemistry\, Medicine\, or related field. \nPreferred Experience: \nExperience in physiology\, anatomy\, and surgery using preclinical models of colon cancer. Performed necropsies\, clinical and/or laboratory experience. Proficient in molecular biology techniques\, such as immunoblotting\, PCR\, RT-PCR\, or cell culture and cloning. Experience in performing rodent tumor bioassays following approved protocols using intra-oral and intra-peritoneal injections. \nRequired Special Knowledge\, Skills\, and Abilities: \nAbility to multi-task and work cooperatively with others. Ability to perform all tasks and job responsibilities safely without injury to self and others\, in compliance with A&M System and TAMHSC guidelines. Provide a safe environment that fosters respect\, inclusion\, and equality. \nJob Responsibilities \n\nPerform Procedures: Perform endoscopies and polypectomies on live study animals\, helping to develop/improve surgical resection protocols on rodent small intestine and colon.\nExperiments: Conduct cell culture\, molecular\, biochemical\, and animal studies to determine the action of chemopreventive compounds in cell culture and tumorigenicity assays. Perform cell culture experiments and molecular techniques such as PCR\, RT-PCR\, Western blotting\, RNA-seq\, and DNA methylation assays to investigate epigenetic mechanisms in GI lesions.\nResearch: Participate in joint projects involving faculty\, postdoctoral fellows\, and research assistants. Assist with research grant proposals and provide publishable reports for conference and journal presentation. This will include library research into new approaches\, the preparation of tables\, graphs\, photographs\, and figures\, and assist in manuscripts and grant proposals. Participate in weekly lab meetings within the center and in local/regional programs relevant to ongoing projects. Participate in joint projects involving faculty\, junior lab personnel\, and graduate students. Provides assistance to graduate students and junior lab personnel.
URL:https://ces.b2sg.org/event/tam-24feb18/
LOCATION:Texas A&M University Health Science Center\, 8441 Riverside Pkwy\, Bryan\, TX\, 77807\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180224
DTEND;VALUE=DATE:20180326
DTSTAMP:20260820T011935
CREATED:20180224T190655Z
LAST-MODIFIED:20180224T190655Z
UID:19684-1519430400-1522022399@ces.b2sg.org
SUMMARY:Research Assistant Professor
DESCRIPTION:An individual is sought to independently direct a project investigating molecular cross-talk between epigenetics and chromatin organization in normal and malignant hematopoiesis using molecular biology\, biochemistry\, fluorescence microscopy\, and NGS-based epigenome profiling methods. The goal of these studies is to identify novel targets and design therapeutic interventions to prevent or delay the development of\, and to treat acute myeloid leukemia.  \n\nDesign and coordinate projects to carry out experiments in animal models of myeloid malignancies and pre-leukemic conditions to evaluate potential therapeutic agents\nPerform epigenomic and chromatin profiling experiments such as ChIP-seq\, ATAC-seq\, MAPit-PATCH\, WGBS\nUse wide field fluorescence and and confocal microscopy to document dynamic changes in chromatin structure in live and fixed hematopoietic cells\nAnalyze\, interpret\, and visually organize data\nWrite manuscripts\nAssist with grant proposal preparation\nWrite technical reports\nTrain and supervise technical personnel\, assist with mentoring of graduate students\nPresent research results at meetings\n\n\nAdvertised Salary: \nCommensurate with education and experience  \nMinimum Requirements: \nPh.D. in molecular biology\, biochemistry\, cancer biology\, molecular genetics\, or related field  \nPreferred Qualifications: \n5+ years of research experience  \nExpertise in cancer epigenetics\, chromatin biology\, transcriptomics\, functional genomics\, and other NGS-based methods as demonstrated by published papers in peer reviewed scientific journals  \nSpecial Instructions to Applicants: \nInterested candidates must apply online. Please upload most recent CV\, Cover Letter of interest\, and three references with contact information. 
URL:https://ces.b2sg.org/event/unifl-24feb18/
LOCATION:University of Florida\, Gainesville\, FL\, 32611\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/06/uni-florida.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180224
DTEND;VALUE=DATE:20180326
DTSTAMP:20260820T011935
CREATED:20180224T193454Z
LAST-MODIFIED:20180224T193654Z
UID:19686-1519430400-1522022399@ces.b2sg.org
SUMMARY:Laboratory Coordinator
DESCRIPTION:We are seeking to recruit a Laboratory Coordinator in the laboratory of Dr. Kevin Gardner in the Department of Pathology and Cell Biology. The Gardner lab studies basic mechanisms of epigenetic gene regulation in breast cancer using both model systems and patient derived material (Proc Natl Acad Sci U S A. 2009 Nov 17;106(46): 19286-91; Nat Struct Mol Biol. 2010 Dec;17(12): 1406-13; Nat Commun. 2012 Jan 17;3:633; Nat Commun. 2013;4:1449).  \nResponsibilities include but are not limited to: \n\nManaging the day to day operations of the laboratory\nMaintenance of cell lines\nCarrying out immunoprecipitation assays\nOrdering and maintaining inventory of laboratory supplies.\nKeeping track of orders and confirming billing\nSetting up and performing experiments involving tissue culture\, western blot\, DNA\, RNA\, analysis\nMaintaining records pertaining to the laboratory\, including records of experimental results.\nOperating\, maintaining and troubleshooting complex equipment (e.g. ABI 7300 Real-Time PCR system)\nAssisting in the training of new hires\, Support Staff employees\, Students and Fellows in laboratory procedures\nImplementing safety regulations\nPerforming other related duties as necessary to the functioning of the laboratory.\n\nMinimum Qualifications for Grade \nApplicant MUST meet these minimum qualifications to be considered an applicant  \nRequires a bachelor’s degree plus two years of related experience or equivalent in education\, training and experience.  \nAdditional Position-Specific Minimum Qualifications \nApplicant MUST meet these minimum qualifications to be considered an applicant  \nThe successful candidate must have extensive common knowledge and skill with basic molecular and cell biology\, including mammalian tissue culture\, RNA isolation\, QPCR\, PCR\, recombinant DNA technology\, immunoblotting\, immunohistochemistry\, viral and plasmid vectors construction\, in situ hybridization\, fluorescence microscopy\, ELISA assay\, conventional reporter fluorescent and bioluminescent assays\, in situ hybridization and fluorescence microscopy.  \nMust be computer literate (MS Access\, MS Excel\, Windows and/or Mac).  \nAbility to work independently\, under minimal supervision.  \nMust demonstrate excellent interpersonal and communication skills.  \nThe incumbent should be able to work independently\, be very well organized and reliable and enjoy working in an interdisciplinary and highly collaborative atmosphere where technical support will be provided for all projects in the lab.  \nSpecial Instructions  \nPreferred Qualifications  \n\nFive years of related experience.\nBachelor’s degree in chemistry\, biology or related science
URL:https://ces.b2sg.org/event/cu-24feb18/
LOCATION:Columbia University Medical Center\, 630 W 168th St\, New York\, NY\, 10032\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180224
DTEND;VALUE=DATE:20180326
DTSTAMP:20260820T011935
CREATED:20180224T203901Z
LAST-MODIFIED:20180224T203919Z
UID:19689-1519430400-1522022399@ces.b2sg.org
SUMMARY:Post-Doctoral Fellow
DESCRIPTION:The Espinosa Laboratory in the Cancer Division of the Department of Pharmacology at the University of Colorado Denver | Anschutz Medical Campus is seeking independent and creative postdoctoral fellows. The Espinosa Lab utilizes an integrated system of functional genomics and mechanistic studies aimed at making biological discoveries with clear translational potential. Most of our current studies are focused on harnessing the power of pleiotropic transcription factors for cancer treatment Examples of ongoing projects are: \n\nElucidation of gene networks governed by transcription factors involved in cancer. We employ functional genomics tools to elucidate the signaling cascades driven by cancer-relevant transcription factors such as p53 and HIF1A across different cell types and stimuli. We aim to elucidate molecular mechanisms that control the cellular response upon activation of these transcription factors\, from enhancer priming to metabolic control\, with the ultimate goal of harnessing these mechanisms for therapeutic purposes (e.g. Galbraith et al.\, Cell 2013\, Allen et al.\, eLife 2014\, Andrysik et. al.\, Genome Res 2017).\nMechanistic studies of transcriptional coactivators and chromatin regulators with oncogenic and tumor suppressive functions. Using a multidimensional approach\, from biochemistry to functional genomics\, we investigate the role of specific transcriptional coactivators and chromatin factors in cancer development. We are particularly interested in the role of the Mediator Complex in oncogenesis and tumor suppression (e.g. Donner et al.\, Mol Cell 2007\, Donner et al.\, Nature Struct Mol Biol. 2010\, Galbraith et al.\, Cell 2013\, Perez-Perri et al. Cell Reports 2016).\nPharmacological manipulation of transcription factors and cofactors for therapeutic purposes. Our goal is to identify effective strategies to employ novel biologically targeted therapeutics modulating the activity of transcription factors\, cofactors and chromatin regulators for cancer treatment. Presently\, we are focused on several first-in-class drugs that modulate transcription factors\, Mediator-associated kinases\, and epigenetic readers (e.g. Sullivan et al.\, Nat Chem Biol. 2012\, Andrysik et al.\, Cell Reports 2013).\nRoles of Interferon signaling in Down syndrome and cancer. We are particularly interested in understanding how hyperactivation of Interferon signaling in people with Down syndrome may contribute to the clinical impacts of trisomy 21\, including the lower incidence of solid malignancies and higher incidence of leukemias observed in this population (e.g. Sullivan et al.\, eLIFE 2016; Sullivan et al.\, Scientific Reports 2017).\n\nOur hope is that these courses of study will lead to clinically actionable discoveries and ultimately improve patient outcomes as well as our understanding of human biology in general. All projects provide ample opportunity for gaining experience with genomic methods to study gene transcription\, expression\, and epigenetic regulation. We also frequently employ shRNA and CRISPR technology\, along with a host of additional advanced molecular\, biochemical\, and genomic techniques. \nQualifications \nMinimum Requirements: \n\nPh.D. in molecular biology or a related field\n\n\nExcellent written and verbal communication skills in English\n\n\nProven ability to work independently within a research lab\n\n\nExperience with mammalian tissue culture\n\nDesired or preferred: \nExperience with molecular biology methods\, such as: \n\nRT/quantitative PCR\nWestern blotting\nRNA interference\nCRISPR / genome editing\nLenti/retroviral production and transduction\nFlow cytometry\n3 years mammalian tissue culture experience\nExperience with rodent models\nExperience with generation and analysis of genomic sequence data\nExperience with standard bioinformatics tools\nExperience with statistical programming\, such as R
URL:https://ces.b2sg.org/event/unico-24feb18/
LOCATION:University of Colorado – School of Medicine\, Aurora\, CO\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180224
DTEND;VALUE=DATE:20180326
DTSTAMP:20260820T011935
CREATED:20180224T205805Z
LAST-MODIFIED:20180224T211233Z
UID:19693-1519430400-1522022399@ces.b2sg.org
SUMMARY:Senior Research Associate
DESCRIPTION:Constellation Pharmaceuticals is a premier epigenetics company\, focused on the discovery and development of novel\, small molecules targeting chromatin regulatory proteins in tumor and immune cells for therapeutic applications in oncology. Our unique discovery platform integrates our understanding of chromatin-regulatory mechanisms with cancer and immune pathways to optimize our drug discovery activities and fully enable the clinical translation of our programs. Our translational capabilities are being currently expanded to ensure the differentiated clinical development of our clinical and pre-clinical assets and we look for talented and experienced individuals who want to participate in developing novel cancer therapeutics. \nResponsibilities: \n\nWork closely with scientists to design and execute cell-based phenotypic and mechanism of action assays in a variety of assay platforms\nGenerate\, analyze\, and catalog data with database tools such as Genedata and software tools such as GraphPad Prism\nPerform standard molecular biology and biochemistry techniques according to established protocols\nDocument all work in electronic notebooks and present data internally at group meetings\nRequirements: \n\nBS/MS in biology or other relevant field\nA minimum of 2-3 years of postgraduate laboratory experience (industry setting preferred)\nExperience with mammalian cell culture and standard molecular biology techniques is essential\nExperience with a variety of cell-based assays (Cell Titer Glo\, ELISA\, flow cytometry) is essential\nAbility to adapt to new roles in a dynamic working environment\, detail oriented with excellent time management skills\nStrong oral and written communication skills and an ability to successfully work as part of an integrated\, interdisciplinary team
URL:https://ces.b2sg.org/event/constellation-24feb18/
LOCATION:Constellation Pharmaceuticals\, 215 First Street\, Cambridge\, MA\, 02142\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180228
DTEND;VALUE=DATE:20180330
DTSTAMP:20260820T011935
CREATED:20180228T120457Z
LAST-MODIFIED:20180228T120546Z
UID:19719-1519776000-1522367999@ces.b2sg.org
SUMMARY:Assistant Scientist
DESCRIPTION:The Sylvester Cancer Center is seeking an Assistant Scientist for the Cancer Epigenetics to work in a highly collaborative\, multi-researcher program investigating the molecular mechanisms of epigenetic regulation of cancer.  \nResponsibilities: We are seeking highly motivated individuals to develop and implement innovative computational approaches for analyzing high throughput genomic and epigenomic data\, including but not limited to\, integrated cancer risk prediction model\, cancer subtype discovery\, genomic and epi-genomic data integration\, single cell RNA-Seq data analysis\, non-coding RNA data analysis\, and other datasets. Projects will include next-generation sequencing based profiling studies of DNA methylation\, hydroxymethylation\, ChIP-seq\, ATAC-seq and RNA-seq to elucidate the role of epigenetic regulation in cancer biology. Applicants should hold a PhD and/or MD degree and have strong computational biology skills. Previous experience with epigenome-wide assays is preferred. The successful candidate will be working in a collaborative environment with multiple faculty members\, biostatisticians and bioinformaticians on translational cancer research.  \nMinimum Qualifications: Ph.D. in Bioinformatics\, Computational Biology\, Biostatistics\, Statistics\, Genetics\, Computer Science\, or a related field. Excellent communications skills in English (both verbal and written). Proficiency in using R/Bioconductor and Perl/Python for genomic data analysis is required. Solid training in quantitative sciences. Experience with R/Bioconductor. Experience with Next-generation sequencing data analysis. Understanding of epigenome biology. Strong programming skills. Strong oral and written communication skills. The ability to work both independently and in a team environment. Ability to write manuscripts independently. 
URL:https://ces.b2sg.org/event/umiami-28feb18/
LOCATION:University of Miami\, 1320 S Dixie Hwy\, Coral Gables\, FL\, 33146\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180228
DTEND;VALUE=DATE:20180330
DTSTAMP:20260820T011935
CREATED:20180228T121528Z
LAST-MODIFIED:20180228T121915Z
UID:19721-1519776000-1522367999@ces.b2sg.org
SUMMARY:Informatics Analyst II
DESCRIPTION:This position will work primarily with scientists and computational experts using Next Generation Sequencing (NGS) data\, such as RNA-sequencing\, miRNA-sequencing\, and Methylation arrays. This position focuses on applied bioinformatics skills in transcriptional profiling and epigenetic analyses in pediatric acute myeloid leukemia. \nResponsibilities \nSpecific Responsibilities Include \n\nProcess diverse NGS datasets prior to analysis.\nImplement standard data quality\, formatting and annotation processes.\nData management and organization for large “omics” datasets ( > 1000 samples).\nVisualization of “omics” data.\nContribution to on-going research projects\, including statistical and bioinformatics support for clinical research fellows\, and molecular biologists.\n\nQualifications \nBasic Qualifications \n\nEnrollment in an accredited graduate degree program.\nAbility to commit to a 9-month\, full-time position.\nProgramming skills in R.\nProgramming skills in Python.\nExperience with computing in a Unix/Linux environment.\nExperience with high performance computing clusters (HPC) and job scheduling systems (SLURM\, Torque\, etc).\n\nAdditional Skills/Preferences \n\nStrong verbal\, written\, and organizational skills.\nAbility to work both independently and in a team.\nCoursework in molecular biology\, algorithms\, and statistics.
URL:https://ces.b2sg.org/event/hutch-28feb18/
LOCATION:Fred Hutchinson Cancer Research Center\, 1100 Fairview Ave. N.\, Seattle\, WA\, 98109-1024\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180228
DTEND;VALUE=DATE:20180330
DTSTAMP:20260820T011935
CREATED:20180228T124534Z
LAST-MODIFIED:20180325T093647Z
UID:19724-1519776000-1522367999@ces.b2sg.org
SUMMARY:Senior Principal Scientist\, Receptor Biochemist
DESCRIPTION:The Pfizer Oncology Research & Development group in La Jolla is seeking a full-time employee to support the drug discovery process to create innovative cancer therapies. The successful candidate will provide expert scientific and technical expertise towards the discovery and pre-clinical development of innovative small molecule drugs for receptor-class protein targets (e.g. GPCR\, NHR\, SLC). The successful candidate will work with a high degree of independence to provide biochemical insight on receptor targets and ligands as well as impact drug discovery project teams at a high strategic level. \nResponsibilities \n\nProvide senior\, strategic\, and technical leadership for the cellular and molecular characterization of receptor targets (GPCR\, nuclear hormone receptors\, membrane transporters\, and ion channels) and the development of effective lead discovery testing-cascades that impact the oncology portfolio and advance innovative drugs through our preclinical pipeline\nLead/ contribute to the establishment of methods to characterize and understand the impact of receptor drug candidates – particularly with regard to assessment of targeted receptor agonist/antagonist interactions (on-/off-target occupancy) and efficacy for multiple preclinical oncology projects\nLead/ contribute to the establishment of programs to identify relevant biomarkers for oncology receptor drug candidates\nDemonstrate strong leadership\, personal accountability and interpersonal skills\, and capability for mentoring junior colleagues (direct reports and others)\, and establish safe\, high-quality lab practices\nEnsure high-quality\, timely documentation in electronic laboratory notebooks and Technical Reports\, and contribute to Regulatory Filings and responses to Regulatory questions as appropriate\nPresent data/ strategy to scientists and management in internal and external venues (technical meetings\, Project Team meetings\, conferences) and publish in peer-reviewed journals\, as appropriate\nMaintain current in relevant literature and innovative technologies and their application to receptor target characterization and understanding\, particularly in areas of tumor cell receptor signaling\, epigenetics\, and immune-oncology\n\nQualifications \n\nThe candidate must have a Ph.D. in biochemistry or cell biology (or related field) with 8+ years of experience in small molecule drug discovery with a strong track record of success.\nThe individual will be a recognized scientific and technical expert with cellular receptors (e.g. GPCR\, NHR) and highly experienced in methods to characterize agonists and antagonists and their biochemical and cellular function/activities.\nA well-established ability to develop robust\, functional in vitro assays for the discovery of small molecule agonist/antagonists of membrane receptors is required.\nCorresponding or senior-authored publications in top-tier journals is also a prerequisite.\nThe candidate must demonstrate strong leadership\, personal accountability and interpersonal skills\, and capability for mentoring junior colleagues (direct reports and others)\, and establish safe\, high-quality lab practices.\nIn addition\, the candidate should display a strong strategic understanding of small molecule drug discovery and have a broad understanding of cross-discipline drug discovery processes within a project team.\nA scientific background in oncology and/or immuno-oncology drug discovery is preferred.\nThe candidate should possess excellent communication skills (written\, verbal)\, proven leadership skills\, and the demonstrated ability to make good decisions and influence teams to advance projects and navigate the complexities of receptor-based drug discovery.
URL:https://ces.b2sg.org/event/pfizer-28feb18/
LOCATION:Pfizer – Pearl River\, NY\, 401 North Middletown Road\, Pearl River\, NY\, 10965\, United States
CATEGORIES:Jobs
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180302
DTEND;VALUE=DATE:20180404
DTSTAMP:20260820T011935
CREATED:20180302T180057Z
LAST-MODIFIED:20180302T180355Z
UID:19728-1519948800-1522799999@ces.b2sg.org
SUMMARY:Institute Research Scientist - Translational Biology
DESCRIPTION:The Institute Research Scientist participates in cross-functional research to identify and validate novel oncology targets\, and applies deep biological insights to then translate these findings into novel oncology therapeutic agents to benefit patients.  \nSalary Range: Min $98\,000 – Mid $122\,500 – Max $147\,000  \nESSENTIAL FUNCTIONS  \n1. Apply and develop basic science tools and methodologies to develop complex strategies and enable advancement of Center projects through leadership and experimental activities.  \n2. Apply cutting edge functional genomics approaches to enable systematic investigation into mechanisms of tumorigenesis and drug resistance.  \n3. Independently design\, execute and interpret in vitro\, ex-vivo and in vivo experiments to validate and explore therapeutic potential of drug targets.  \n4. Work with research and bioinformatics teams to utilize internal biological and oncogenomic data sets to generate and test biological hypotheses.  \n5. Work with medicinal chemistry and pharmacology teams as part of drug discovery efforts to validate targets and optimize novel small molecule therapeutics.  \n6. Lead drug discovery biology efforts to selection of lead candidate molecules and transition into clinical development.  \n7. Develop and implement biomarker strategies to guide early clinical development of drugs.  \n8. Design and develop cell and molecular assays to define mechanism of action for compounds\, identify pharmacodynamic assays to be used in pre-clinical and clinical setting and test patient selection strategies.  \n9. Develop extensive knowledge and experience in key areas of tumor biology including\, but not limited to oncogenic signaling\, tumor microenvironment\, tumor immunology\, metabolism\, epigenetic deregulation or apoptosis.  \n10. Adapt to new technologies and find solutions to related program studies.  \n11. Interpret\, present and report research findings at internal meetings and external scientific conferences.  \nEducation  \nRequired: Bachelor’s degree in Biology\, Biochemistry\, molecular biology\, cell biology\, enzymology\, pharmacology\, chemistry or related field.  \nPreferred: PhD in Biological Science or Medical degree strongly preferred  \nExperience  \nRequired: Ten years of relevant research laboratory experience. With Master’s degree\, eight years of required experience and with PhD\, two years of required experience.  \nPreferred: At least two years of relevant experience in oncology research in biotech or pharmaceutical environment.  \n– Experience with genetic (ie RNAi and cDNAs) and pharmacological (i.e. small molecule inhibitors or antibodies) approaches to study target biology utilizing state of the art molecular biology and biochemistry methods and assays essential to drive projects.  \n– Experience working with chemists\, in vitro and in vivo pharmacologists to develop and utilize assays in support of the development of small molecules for target validation and as part of compound lead optimization for the development of novel therapeutics is highly desirable.  \n– A demonstrated track record in the development and implementation of functional genomics strategies to enable systematic investigation into mechanisms of tumorigenesis and drug resistance.  \n– Broad knowledge of cell culture techniques is required and knowledge of how to utilize in vivo oncology models is desirable. Hands-on experience utilizing genetically engineered mouse models and orthotopic or subcutaneous primary or established tumor cell line xenograft models is desirable.  \n– Extensive knowledge and experience in key areas of tumor biology including\, but not limited to oncogenic signaling\, tumor microenvironment\, tumor immunology\, metabolism\, epigenetic deregulation or anti-apoptosis as evidenced by publication in peer-reviewed journals.  \n– Strong data analysis skills\, ability to interpret results and contribute to the design of follow-up experiments\, troubleshoot issues with assay performance\, and effectively present results and conclusions to co-workers\, collaborators and senior leadership.
URL:https://ces.b2sg.org/event/mda-2mar18/
LOCATION:MD Anderson Cancer Center\, 1515 Holcombe Blvd\, Houston\, TX\, 77030\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180303
DTEND;VALUE=DATE:20180405
DTSTAMP:20260820T011935
CREATED:20180303T191059Z
LAST-MODIFIED:20180303T191059Z
UID:19731-1520035200-1522886399@ces.b2sg.org
SUMMARY:Research Associate
DESCRIPTION:USC’s Keck School of Medicine\, Department of Pathology\, Southern California Research Center for ALPD and Cirrhosis\, is seeking a Research Associate to join its team to pursue cutting-edge research on NIH-funded project(s) pertaining to cellular\, molecular\, and metabolic mechanisms of liver inflammation\, fibrosis\, and cancer. The incumbent will productively engage in cellular\, molecular and metabolic mechanisms of liver inflammation\, fibrosis\, and cancer with primary focus on epigenetic reprogramming and activation/reactivation of hepatic stellate cells and alcoholic liver fibrosis leading to publication and federal grant applications.  \nThe candidate must be able to communicate both verbally and in writing to maintain sound scientific communications with colleagues on and off-campus. The Research Associate plans\, designs and conducts highly technical and complex research projects independently and in consultation with supervisor. The Research Associate analyzes research data and provides interpretations; contributes to the development of research documentation for publication and/or prepares technical reports\, papers and/or records.  \nThe applicant must have a Ph.D. or equivalent degree in cell and molecular biology and a minimum of 3 to 4 years basic science experiences in cell and molecular biology. The Keck School of Medicine Department of Pathology is one of the largest pathology departments in the United States. The Department aims to shape the future of pathology as it will be practiced in community hospitals\, academic medical centers and clinical laboratories throughout the country. The position offers a competitive salary with excellent university benefits. This is a grant-funded position.  \n\nMinimum Education: Ph.D. or equivalent doctorate \nMinimum Experience: 1 year \nMinimum Field of Expertise: Directly related education and experience in research specialization with advanced knowledge of equipment\, procedures and analysis methods.
URL:https://ces.b2sg.org/event/usc-3mar18/
LOCATION:University of Southern California\, Los Angeles\, CA\, 90007\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180303
DTEND;VALUE=DATE:20180405
DTSTAMP:20260820T011935
CREATED:20180303T192448Z
LAST-MODIFIED:20180303T192449Z
UID:19733-1520035200-1522886399@ces.b2sg.org
SUMMARY:Research Fellow - Cancer Biology
DESCRIPTION:Postdoctoral positions are available in the Department of Cancer Biology to understand the biology of cancer stem cells\, cancer progression and metastasis. We use molecular biology\, biochemical and mouse modeling approaches to dissect the role of posttranslational modifications\, such as protein ubiquitination and methylation in signaling pathways\, metabolism\, cancer immunity\, epigenetics and DNA damage response and their potential applications for cancer drug development. 
URL:https://ces.b2sg.org/event/wfbh-3mar18/
LOCATION:Wake Forest Baptist Health\, Winston-Salem\, NC\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180303
DTEND;VALUE=DATE:20180406
DTSTAMP:20260820T011935
CREATED:20180303T193121Z
LAST-MODIFIED:20180303T193121Z
UID:19739-1520035200-1522972799@ces.b2sg.org
SUMMARY:Postdoc Fellow - Cancer Biology (Myeloma)
DESCRIPTION:Translational Development at Celgene is pleased to present a growth opportunity for outstanding post-doctoral fellows with a passion for hematology-oncology research and clinical development towards improved outcomes in myeloma patient healthcare. The multiple myeloma Translational Development team currently employs state of the art platforms and analytics to address the most important questions that will drive the current and next generation of therapeutic development for myeloma patients. \nThe successful candidate will become part of diverse team with a unified bench-to-bedside vision in precision healthcare and diagnostic approaches to biomarker utilization. The overarching goal of the successful candidate will be to provide\, through passionate research efforts\, clinically implementable information to better understand how patient characteristics\, malignancy biology and immune context features align to define patient outcomes from treatment with portfolio therapeutics and enable rationale combo design. This fellowship will work alongside top shelf scientists with deep knowledge of myeloma disease biology and further expertise including genomic definition of risk and outcomes\, immune characterization\, definition of response and tumoral evolution using single cell platforms and lab-based screens to better understand mechanistics of clinically-observed phenomenon. \nSkills/Knowledge Required: \n\nPhD in cancer biology\, genetics\, epigenetics\nStrong background in disease or mechanism based studies using modern experimental and computational methods is required.\nKnowledge of myeloma is desirable but not required.\nExperience in heme malignancy related areas\nWhile understanding of epigenetics and epigenetic experimental approaches are not essential\, it is highly desirable.\nPrior experience in molecular\, cellular\, functional and computational methods\nAbility to formulate experimental ideas\nDemonstrated writing and commutation skills\nAbility work in a collaborative team science environment
URL:https://ces.b2sg.org/event/celgene-3mar18/
LOCATION:Celgene\, 86 Morris Ave\, Summit\, NJ\, 07901\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180304
DTEND;VALUE=DATE:20180406
DTSTAMP:20260820T011935
CREATED:20180304T093152Z
LAST-MODIFIED:20180304T093152Z
UID:19743-1520121600-1522972799@ces.b2sg.org
SUMMARY:Postdoctoral Associate
DESCRIPTION:A postdoctoral associate position is available in the laboratory of Dr. Jennifer Trowbridge at The Jackson Laboratory in Bar Harbor\, Maine to study epigenetic mechanisms governing hematopoietic stem cell lineage commitment\, and how deregulation of epigenetic modifications leads to myeloproliferative disorders including leukemia. ( http://trowbridgelab.com )  \nThe Jackson Laboratory (JAX) offers a unique research and training environment characterized by multidisciplinary scientific collaboration\, unparalleled mouse resources\, outstanding core services\, and is located adjacent to Acadia National Park in coastal Bar Harbor\, Maine. Translational research collaborations in genomics-based\, personalized medicine are fostered through our new JAX Genomic Medicine campus in Farmington\, CT. In addition to lab-based training\, JAX has developed a unique program for trainees to expand their professional skills in science communication\, entrepreneurship\, teaching\, mentoring and laboratory management to best prepare postdocs for future career opportunities.  \nRequired Skills  \nAssociate must be able to plan\, execute and analyze an independent research project\, as well as exceptional verbal and written communication skills. Preference given to self-motivated and career oriented individuals.  \nRequired Experience  \nA Ph.D. in biological or related sciences is required\, and a strong training background in molecular biology\, cell biology and/or epigenetics is preferred.
URL:https://ces.b2sg.org/event/jax-4mar18/
LOCATION:Jackson Laboratory\, 600 Main Street\, Bar Harbor\, ME\, 04609\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180304
DTEND;VALUE=DATE:20180406
DTSTAMP:20260820T011935
CREATED:20180304T093837Z
LAST-MODIFIED:20180304T093837Z
UID:19745-1520121600-1522972799@ces.b2sg.org
SUMMARY:Postdoctoral Fellow
DESCRIPTION:Position Summary and Key Responsibilities:\nPostdoctoral position: Characterizing cancer progression and metastasis  \nTo develop and characterize solid cancer model systems in order to study epigenetic changes contributing to cancer progression and metastasis. These models will aid in the discovery of promising targets and evaluation of treatment strategies. The overall goal of these pre-clinical studies will be to provide supporting data for the potential clinical translation of novel\, effective therapeutic approaches.  \nPlease include CV with publication record and (if applicable) previous/current grant funding.  \nMinimum Education and Skills Required for Consideration:\nPh.D. with emphasis in oncology and/or epigenetics\, but will also consider biochemistry\, immunology or microbiology background with experience in cancer or epigenetics research.  \nExperience in flow cytometry is preferred  \nMouse handling with proficiency in different routes of injection.  \nStrong critical thinking skills and ability to troubleshoot. 
URL:https://ces.b2sg.org/event/hope-4mar18/
LOCATION:City of Hope\, 1500 East Duarte Road\, Duarte\, 91010\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180304
DTEND;VALUE=DATE:20180406
DTSTAMP:20260820T011935
CREATED:20180304T123009Z
LAST-MODIFIED:20180304T123047Z
UID:19747-1520121600-1522972799@ces.b2sg.org
SUMMARY:Postdoctoral Scientist
DESCRIPTION:Come work for an organization where everything matters. \nSummary:\nWorks under the mentorship of Dr. Stephen Lessnick\, the Director of the Center for Childhood Cancer and Blood Diseases at Nationwide Children’s Hospital Research Institute (NCHRI). Dr. Lessnick’s laboratory is focused on the molecular basis of Ewing sarcoma development\, with a particular emphasis on the transcriptional and epigenetic functions of the EWS/FLI fusion oncogenic transcription factor. The successful applicant will have basic skills in molecular biology and tissue culture\, but will also bring and apply new areas of expertise to the laboratory. Of particular interest are individuals with expertise any of the following areas: biochemistry\, biophysics\, epigenetics\, transcriptional analysis\, computation biology\, etc. The successful applicant will have an early track-record of publication success\, will be able to work independently and develop collaborations as-needed\, and will also mentor junior trainees\, technicians\, and others in the lab. \nResponsibilities:\nWith guidance from a CRI mentor\, design experiments and develops protocols required to conduct productive research in a specific scientific area. After the study has been designed\, performs the research work in accordance with the protocol. \nHelps to train and supervise technical support staff in performing specific techniques essential to carrying out the research program. \nRecords and analyzes data generated by the research study\, and helps to plan future research endeavors. \nPrepares scientific and technical papers from the results of the research work. Publishes papers in appropriate refereed scientific journals. Presents findings at local (particularly CRI research meetings) and national research forums. \nIf appropriate\, collaborates with other ongoing research efforts either at CRI or at The Ohio State University. \nThis is considered a training position therefore the RI will allow a trainee 5 years to advance beyond the level of Post Doc. \nWorks toward research independence. Prepares to submit proposals to and obtain funding from external granting agencies. \nOther information:\nREPORTING RELATIONSHIPS\nReports to: Either established CRI principal investigator (i.e. OSU faculty member) or a CRI Senior Research Scientist for guidance in research endeavors \nKNOWLEDGE \, SKILLS AND ABILITIES REQUIRED\nMD\, Ph.D\, Pharm.D.\, or equivalent degree in PhD in Molecular Biology\, Biochemistry\, or Biomedical Sciences\, Cellular and Molecular Biology\, Biophysics\, Bioinformatics \n2. Necessary technical skills in the appropriate area of research. \n3. Ability to do technical writing\, and good communication skills.
URL:https://ces.b2sg.org/event/nchri-4mar18/
LOCATION:Nationwide Children’s Hospital Research Institute\, 700 Children's Dr\, Columbus\, OH\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180305
DTEND;VALUE=DATE:20180407
DTSTAMP:20260820T011935
CREATED:20180305T075636Z
LAST-MODIFIED:20180305T075636Z
UID:19756-1520208000-1523059199@ces.b2sg.org
SUMMARY:Research Investigator
DESCRIPTION:We are seeking a highly motivated bioinformatician to join our Translational Bioinformatics Immunoscience (IMS) and Small Molecule Immuno-Oncology (smIO) team. The successful candidate will help advance Bristol-Myers Squibb’s industry leading IMS and IO pipelines through the strategic application of cutting edge bioinformatics approaches. This team interacts with and influences all aspects at BMS from early discovery through development. \nResponsibilities \nAnalyze various -omic-scale data including RNA-Seq\, Exome and Whole Genome Sequencing\, single cell sequencing\, high throughput proteomics\, and multiplex flow cytometry in order to nominate novel drug targets\, enable patient enrichment strategies\, and prioritize combination therapies. \nIntegrate and mine large-scale external data sets (GEO\, TCGA\, 1KG\, EXAC\, Cosmic) to further our understanding of autoimmune diseases and cancer pathogenesis. \nCollaborate with bioinformaticians\, statisticians and biologists to implement and execute bioinformatics and statistical analysis plans. \nQualifications: \n\nPh.D. in bioinformatics\, engineering\, statistics\, physics\, molecular biology\, genetics\, or a similar discipline.\nStrong background in -omic (DNA\, RNA\, epigenetic\, proteomic) data analysis and biological interpretation\nSolid background in Immunoscience and/or Immuno-Oncology biology.\nAbility to communicate effectively with biologists\, biostatisticians and computational scientists.\nProficiency using R and Bioconductor packages\, at least one scripting language (Python\, Perl)\, and SQL.\nExperience working with Linux high performance compute clusters and cloud based computing platforms (Amazon EC2).\nWorking knowledge of commercial and publicly available biological databases including NCBI\, Ensembl\, ArrayExpress/GEO\, SRA\, TCGA and 1000 Genomes is expected.\nFluency in NGS experiments and data analysis (e.g. GATK\, Cufflinks\, SAMtools\, BAMtools etc.) is preferred.\nExperience working with data from clinical trials is a plus.
URL:https://ces.b2sg.org/event/bms-5mar18/
LOCATION:Bristol-Myers Squibb\, Princeton\, NJ\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180308
DTEND;VALUE=DATE:20180410
DTSTAMP:20260820T011935
CREATED:20180308T175951Z
LAST-MODIFIED:20180308T181236Z
UID:19760-1520467200-1523318399@ces.b2sg.org
SUMMARY:Postdoctoral Fellowship - Genetics\, Epigenetic Regulation
DESCRIPTION:Positions of two postdoctoral scientistsare open now in the Chen laboratory ( https://www.cityofhope.org/faculty/jianjun-chen ). Our group is interested in discovering novel genetic and epigenetic regulations and deciphering their underlying molecular mechanisms in normal developmental processes (e.g.\, hematopoiesis) and tumorigenesis (e.g.\, leukemogenesis). We cover research areas with relevance to Hematology\, Immunology\, and Cancer Biology\, with an emphasis on RNA epigenetics (mainly focusing on the N 6 methyladenosine (m 6 A) modification) and DNA epigenetics (mainly focusing on the TET1/2/3-mediated DNA demethylation) associated basic and translational research. Our research involves experiments with primary human cancer cells\, cancer and stem cell transplantation models\, mouse genetics\, classic molecular\, biochemistry and cell biology\, functional genomics\, signal transduction\, and large-scale data analysis and computational biology.  \nMinimum Education and Skills Required for Consideration:\nThe candidates for the Postdoctoral scientist positions should have a Ph.D. and/or M.D. degree(s)\, and a solid background in biochemistry\, mouse model studies\, hematology\, epigenetics\, immunology\, pathology\, and/or stem cell research is preferred for. The candidates should not have more than three years of postdoc training experience. The candidates should be highly motivated individuals with the ability to work in a team environment and with good oral and written communication skills in English.  \nApplication:\nPlease apply to this job posting. Additionally\, your application\, including CV\, brief motivation statement\, and contact information of three scientific mentors (references)\, should be saved as a single PDF. The PDF file can be sent to Dr. Jianjun Chen ( jianchen@coh.org ) directly. 
URL:https://ces.b2sg.org/event/hope-8mar18/
LOCATION:City of Hope\, 1500 East Duarte Road\, Duarte\, 91010\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180308
DTEND;VALUE=DATE:20180410
DTSTAMP:20260820T011935
CREATED:20180308T181000Z
LAST-MODIFIED:20180308T181000Z
UID:19762-1520467200-1523318399@ces.b2sg.org
SUMMARY:Postdoctoral Associate - Cancer Epigenetics
DESCRIPTION:The Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine has an exciting opportunity for a Postdoctoral Associate in the Cancer Epigenetics Program. This position will work in a highly collaborative environment investigating the molecular mechanisms of epigenetic regulation of leukemia and normal hematopoiesis.  \nSpecifically\, we are seeking a highly motivated Postdoctoral Associate with in-depth knowledge and extensive skills in cellular and molecular biology to join the lab. The Postdoctoral Associate should demonstrate expertise in various laboratory techniques including cell culture and molecular biology assays (molecular cloning\, cell proliferation assay\, subpopulation analysis by FACS\, stable and transient transfection\, use of shRNA and viral constructs)\, preparation and analysis of DNA and RNA (preparation of plasmids\, regular PCR and RT-PCR)\, chromatin immunoprecipitation (ChIP) assays\, biochemical assays (ELISA\, immunoblotting\, Co-IP). Prior experience in epigenetics in preferred but not required. Prior experience in hematopoiesis/leukemia models\, molecular biology\, cancer genetics or epigenetics\, and/or development of animal models is required. It is expected that the Postdoctoral Associate will have the ability to work independently\, design experiments with appropriate controls\, collect and tabulate data\, publish and present results\, as well as to participate in the training of graduate and rotation students in a research laboratory setting. Projects will include in vivo and in vitro modeling of candidate genes to identify epigenetically silenced genes that contribute to the development of hematopoietic malignancies and characterization of candidate genes using in vitro and in vivo systems.  \nThe minimum qualifications for this position are as follows: Ph.D. and/or M.D. with strong molecular biology or cancer biology skills. Previous experience with epigenetics\, cancer modeling or hematopoiesis is preferred. Evidence of scholarly ability (record of publication in peer-reviewed journals\, etc.) must be presented. Ability to communicate in written and spoken English is required. The Postdoctoral Associate will be working in a collaborative environment that includes wet bench cancer biologists and computational biologists. 
URL:https://ces.b2sg.org/event/umiami-8mar18/
LOCATION:University of Miami\, 1320 S Dixie Hwy\, Coral Gables\, FL\, 33146\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180309
DTEND;VALUE=DATE:20180411
DTSTAMP:20260820T011935
CREATED:20180309T171506Z
LAST-MODIFIED:20180309T171506Z
UID:19765-1520553600-1523404799@ces.b2sg.org
SUMMARY:Postdoctoral Scientist
DESCRIPTION:JOB SUMMARY: Working independently but in close cooperation and in consultation with the Principal Investigator and other Research Scientist\, the Research Fellow will perform routine and complex laboratory procedures throughout training period. May develop\, adapt\, and implement new research techniques and protocols. Analyzes and interprets data. May assist in preparation of grant proposals. Participates in publications and presentations as author or co-author. Not responsible for generating grant funds.  \nESSENTIAL JOB DUTIES AND RESPONSIBILITIES: May assist in preparation of grant proposals\, but is not responsible for generating grant funds. May participate in publications and presentations as author or co-author. Designs and performs experiments. Will keep appropriate experimental records and documentation and analyze the results with the Principal Investigator. May develop\, adapt\, and implement new research techniques and protocols. Analyzes\, interprets\, summarizes and compiles data. Performs routine and complex laboratory procedures throughout training period. Operates and maintains equipment and instruments.  \nDEPARTMENT AND/OR UNIT SPECIFIC – ESSENTIAL JOB RESPONSIBILITIES: The Postdoctoral Scientist investigates mechanisms of progenitor cell expansion in the healthy lung and in lung cancer. Projects include defining genetic and epigenetic mechanisms that regulate progenitor cell renewal versus differentiation and how this changes in the setting of lung cancer. Experimental approaches employed in the laboratory include disease modeling using genetically modified mice\, prospective isolation and cultivation of lung stem cells\, isolation and culture of human lung epithelial cells from patient-derived samples and advanced genomics approaches for single cell gene expression profiling and epigenetic analysis.  \nQualification Requirements/Preferences:\nEducation Certifications/Licensure Experience Physical Abilities Educational Requirements:\nDoctorate (MD\, PhD\, VMD\, or DDS) in area directly related to field of research specialization. \nExperience:\nWorks independently on research projects designed by a mentor (typically the PI) within area of specialization. Acquires thorough technical and theoretical knowledge of research project and objectives during one to five (1-5) year post-doctoral appointment. Demonstrated aptitude to perform experimental protocols and procedures\, including detailed data collection\, and analysis and operation and maintenance of specialized equipment. Knowledge of safety standards and maintenance of specialized equipment.
URL:https://ces.b2sg.org/event/cedars-9mar18/
LOCATION:Cedars-Sinai Medical Center\, Los Angeles\, 8700 Beverly Blvd\, Los Angeles\, CA\, 90048\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180309
DTEND;VALUE=DATE:20180411
DTSTAMP:20260820T011935
CREATED:20180309T173033Z
LAST-MODIFIED:20180309T173238Z
UID:19767-1520553600-1523404799@ces.b2sg.org
SUMMARY:Postdoctoral Associate - Cancer Research
DESCRIPTION:The laboratory of Dr. Enrique Mesri at the University of Miami Miller School of Medicine’s Department of Microbiology and Immunology and the Tumor Biology Program of Sylvester Comprehensive Cancer Center\, in collaboration with a multidisciplinary team led by Dr. Michael Samuels of the Department of Radiation Oncology\, has an exciting opportunity for a Postdoctoral Associate with relevant experience. This position will lead a project evaluating key viral\, genomic\, and epigenetic correlates of clinical presentation and outcomes of HPV-associated oropharynx cancer. Work includes\, but is not limited to\, analysis of tumor samples and biological fluids derived from ongoing clinical studies.  \nThe minimum qualifications for this position are as follows: Ph.D.\, M.D.\, or other doctoral level degree in a related field of life science study. Possess a strong background and first author publication(s) in cancer biology\, virology\, molecular and cellular biology\, or a closely related field of study. Prefer experience working with cell\, animal\, or clinical models in virally induced human cancers. Applicants with experience\, or who are familiar with bioinformatic tools (particularly next generation sequencing data analysis)\, are encouraged to apply. Must be goal-oriented\, proactive\, and hardworking with excellent organizational skills and a passion for making a difference in cancer research. Ability to manage day-to-day operations of the laboratory\, mentoring new staff\, and assisting senior researchers in their presentation and funding efforts. A highly motivated individual is sought who can work effectively in a team as well as independently. Applicants should upload a CV when applying that contains a cover letter\, references\, and complete list of publications\, including representative publications as part of the CV. 
URL:https://ces.b2sg.org/event/umiami-9mar18/
LOCATION:University of Miami\, 1320 S Dixie Hwy\, Coral Gables\, FL\, 33146\, United States
CATEGORIES:Jobs
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END:VEVENT
END:VCALENDAR