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X-WR-CALNAME:Cancer Epigenetics Society
X-ORIGINAL-URL:https://ces.b2sg.org
X-WR-CALDESC:Events for Cancer Epigenetics Society
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TZID:Europe/Paris
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TZOFFSETFROM:+0100
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DTSTART:20180325T010000
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DTSTART:20181028T010000
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180224
DTEND;VALUE=DATE:20180325
DTSTAMP:20260820T153959
CREATED:20180224T063337Z
LAST-MODIFIED:20180224T063413Z
UID:19678-1519430400-1521935999@ces.b2sg.org
SUMMARY:Postdoctoral Research Associate
DESCRIPTION:Preferred Education: \nPh.D. Biology\, Biochemistry\, Medicine\, or related field. \nPreferred Experience: \nExperience in physiology\, anatomy\, and surgery using preclinical models of colon cancer. Performed necropsies\, clinical and/or laboratory experience. Proficient in molecular biology techniques\, such as immunoblotting\, PCR\, RT-PCR\, or cell culture and cloning. Experience in performing rodent tumor bioassays following approved protocols using intra-oral and intra-peritoneal injections. \nRequired Special Knowledge\, Skills\, and Abilities: \nAbility to multi-task and work cooperatively with others. Ability to perform all tasks and job responsibilities safely without injury to self and others\, in compliance with A&M System and TAMHSC guidelines. Provide a safe environment that fosters respect\, inclusion\, and equality. \nJob Responsibilities \n\nPerform Procedures: Perform endoscopies and polypectomies on live study animals\, helping to develop/improve surgical resection protocols on rodent small intestine and colon.\nExperiments: Conduct cell culture\, molecular\, biochemical\, and animal studies to determine the action of chemopreventive compounds in cell culture and tumorigenicity assays. Perform cell culture experiments and molecular techniques such as PCR\, RT-PCR\, Western blotting\, RNA-seq\, and DNA methylation assays to investigate epigenetic mechanisms in GI lesions.\nResearch: Participate in joint projects involving faculty\, postdoctoral fellows\, and research assistants. Assist with research grant proposals and provide publishable reports for conference and journal presentation. This will include library research into new approaches\, the preparation of tables\, graphs\, photographs\, and figures\, and assist in manuscripts and grant proposals. Participate in weekly lab meetings within the center and in local/regional programs relevant to ongoing projects. Participate in joint projects involving faculty\, junior lab personnel\, and graduate students. Provides assistance to graduate students and junior lab personnel.
URL:https://ces.b2sg.org/event/tam-24feb18/
LOCATION:Texas A&M University Health Science Center\, 8441 Riverside Pkwy\, Bryan\, TX\, 77807\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180224
DTEND;VALUE=DATE:20180326
DTSTAMP:20260820T153959
CREATED:20180224T190655Z
LAST-MODIFIED:20180224T190655Z
UID:19684-1519430400-1522022399@ces.b2sg.org
SUMMARY:Research Assistant Professor
DESCRIPTION:An individual is sought to independently direct a project investigating molecular cross-talk between epigenetics and chromatin organization in normal and malignant hematopoiesis using molecular biology\, biochemistry\, fluorescence microscopy\, and NGS-based epigenome profiling methods. The goal of these studies is to identify novel targets and design therapeutic interventions to prevent or delay the development of\, and to treat acute myeloid leukemia.  \n\nDesign and coordinate projects to carry out experiments in animal models of myeloid malignancies and pre-leukemic conditions to evaluate potential therapeutic agents\nPerform epigenomic and chromatin profiling experiments such as ChIP-seq\, ATAC-seq\, MAPit-PATCH\, WGBS\nUse wide field fluorescence and and confocal microscopy to document dynamic changes in chromatin structure in live and fixed hematopoietic cells\nAnalyze\, interpret\, and visually organize data\nWrite manuscripts\nAssist with grant proposal preparation\nWrite technical reports\nTrain and supervise technical personnel\, assist with mentoring of graduate students\nPresent research results at meetings\n\n\nAdvertised Salary: \nCommensurate with education and experience  \nMinimum Requirements: \nPh.D. in molecular biology\, biochemistry\, cancer biology\, molecular genetics\, or related field  \nPreferred Qualifications: \n5+ years of research experience  \nExpertise in cancer epigenetics\, chromatin biology\, transcriptomics\, functional genomics\, and other NGS-based methods as demonstrated by published papers in peer reviewed scientific journals  \nSpecial Instructions to Applicants: \nInterested candidates must apply online. Please upload most recent CV\, Cover Letter of interest\, and three references with contact information. 
URL:https://ces.b2sg.org/event/unifl-24feb18/
LOCATION:University of Florida\, Gainesville\, FL\, 32611\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/06/uni-florida.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180224
DTEND;VALUE=DATE:20180326
DTSTAMP:20260820T153959
CREATED:20180224T193454Z
LAST-MODIFIED:20180224T193654Z
UID:19686-1519430400-1522022399@ces.b2sg.org
SUMMARY:Laboratory Coordinator
DESCRIPTION:We are seeking to recruit a Laboratory Coordinator in the laboratory of Dr. Kevin Gardner in the Department of Pathology and Cell Biology. The Gardner lab studies basic mechanisms of epigenetic gene regulation in breast cancer using both model systems and patient derived material (Proc Natl Acad Sci U S A. 2009 Nov 17;106(46): 19286-91; Nat Struct Mol Biol. 2010 Dec;17(12): 1406-13; Nat Commun. 2012 Jan 17;3:633; Nat Commun. 2013;4:1449).  \nResponsibilities include but are not limited to: \n\nManaging the day to day operations of the laboratory\nMaintenance of cell lines\nCarrying out immunoprecipitation assays\nOrdering and maintaining inventory of laboratory supplies.\nKeeping track of orders and confirming billing\nSetting up and performing experiments involving tissue culture\, western blot\, DNA\, RNA\, analysis\nMaintaining records pertaining to the laboratory\, including records of experimental results.\nOperating\, maintaining and troubleshooting complex equipment (e.g. ABI 7300 Real-Time PCR system)\nAssisting in the training of new hires\, Support Staff employees\, Students and Fellows in laboratory procedures\nImplementing safety regulations\nPerforming other related duties as necessary to the functioning of the laboratory.\n\nMinimum Qualifications for Grade \nApplicant MUST meet these minimum qualifications to be considered an applicant  \nRequires a bachelor’s degree plus two years of related experience or equivalent in education\, training and experience.  \nAdditional Position-Specific Minimum Qualifications \nApplicant MUST meet these minimum qualifications to be considered an applicant  \nThe successful candidate must have extensive common knowledge and skill with basic molecular and cell biology\, including mammalian tissue culture\, RNA isolation\, QPCR\, PCR\, recombinant DNA technology\, immunoblotting\, immunohistochemistry\, viral and plasmid vectors construction\, in situ hybridization\, fluorescence microscopy\, ELISA assay\, conventional reporter fluorescent and bioluminescent assays\, in situ hybridization and fluorescence microscopy.  \nMust be computer literate (MS Access\, MS Excel\, Windows and/or Mac).  \nAbility to work independently\, under minimal supervision.  \nMust demonstrate excellent interpersonal and communication skills.  \nThe incumbent should be able to work independently\, be very well organized and reliable and enjoy working in an interdisciplinary and highly collaborative atmosphere where technical support will be provided for all projects in the lab.  \nSpecial Instructions  \nPreferred Qualifications  \n\nFive years of related experience.\nBachelor’s degree in chemistry\, biology or related science
URL:https://ces.b2sg.org/event/cu-24feb18/
LOCATION:Columbia University Medical Center\, 630 W 168th St\, New York\, NY\, 10032\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180224
DTEND;VALUE=DATE:20180326
DTSTAMP:20260820T153959
CREATED:20180224T203901Z
LAST-MODIFIED:20180224T203919Z
UID:19689-1519430400-1522022399@ces.b2sg.org
SUMMARY:Post-Doctoral Fellow
DESCRIPTION:The Espinosa Laboratory in the Cancer Division of the Department of Pharmacology at the University of Colorado Denver | Anschutz Medical Campus is seeking independent and creative postdoctoral fellows. The Espinosa Lab utilizes an integrated system of functional genomics and mechanistic studies aimed at making biological discoveries with clear translational potential. Most of our current studies are focused on harnessing the power of pleiotropic transcription factors for cancer treatment Examples of ongoing projects are: \n\nElucidation of gene networks governed by transcription factors involved in cancer. We employ functional genomics tools to elucidate the signaling cascades driven by cancer-relevant transcription factors such as p53 and HIF1A across different cell types and stimuli. We aim to elucidate molecular mechanisms that control the cellular response upon activation of these transcription factors\, from enhancer priming to metabolic control\, with the ultimate goal of harnessing these mechanisms for therapeutic purposes (e.g. Galbraith et al.\, Cell 2013\, Allen et al.\, eLife 2014\, Andrysik et. al.\, Genome Res 2017).\nMechanistic studies of transcriptional coactivators and chromatin regulators with oncogenic and tumor suppressive functions. Using a multidimensional approach\, from biochemistry to functional genomics\, we investigate the role of specific transcriptional coactivators and chromatin factors in cancer development. We are particularly interested in the role of the Mediator Complex in oncogenesis and tumor suppression (e.g. Donner et al.\, Mol Cell 2007\, Donner et al.\, Nature Struct Mol Biol. 2010\, Galbraith et al.\, Cell 2013\, Perez-Perri et al. Cell Reports 2016).\nPharmacological manipulation of transcription factors and cofactors for therapeutic purposes. Our goal is to identify effective strategies to employ novel biologically targeted therapeutics modulating the activity of transcription factors\, cofactors and chromatin regulators for cancer treatment. Presently\, we are focused on several first-in-class drugs that modulate transcription factors\, Mediator-associated kinases\, and epigenetic readers (e.g. Sullivan et al.\, Nat Chem Biol. 2012\, Andrysik et al.\, Cell Reports 2013).\nRoles of Interferon signaling in Down syndrome and cancer. We are particularly interested in understanding how hyperactivation of Interferon signaling in people with Down syndrome may contribute to the clinical impacts of trisomy 21\, including the lower incidence of solid malignancies and higher incidence of leukemias observed in this population (e.g. Sullivan et al.\, eLIFE 2016; Sullivan et al.\, Scientific Reports 2017).\n\nOur hope is that these courses of study will lead to clinically actionable discoveries and ultimately improve patient outcomes as well as our understanding of human biology in general. All projects provide ample opportunity for gaining experience with genomic methods to study gene transcription\, expression\, and epigenetic regulation. We also frequently employ shRNA and CRISPR technology\, along with a host of additional advanced molecular\, biochemical\, and genomic techniques. \nQualifications \nMinimum Requirements: \n\nPh.D. in molecular biology or a related field\n\n\nExcellent written and verbal communication skills in English\n\n\nProven ability to work independently within a research lab\n\n\nExperience with mammalian tissue culture\n\nDesired or preferred: \nExperience with molecular biology methods\, such as: \n\nRT/quantitative PCR\nWestern blotting\nRNA interference\nCRISPR / genome editing\nLenti/retroviral production and transduction\nFlow cytometry\n3 years mammalian tissue culture experience\nExperience with rodent models\nExperience with generation and analysis of genomic sequence data\nExperience with standard bioinformatics tools\nExperience with statistical programming\, such as R
URL:https://ces.b2sg.org/event/unico-24feb18/
LOCATION:University of Colorado – School of Medicine\, Aurora\, CO\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180224
DTEND;VALUE=DATE:20180326
DTSTAMP:20260820T153959
CREATED:20180224T205805Z
LAST-MODIFIED:20180224T211233Z
UID:19693-1519430400-1522022399@ces.b2sg.org
SUMMARY:Senior Research Associate
DESCRIPTION:Constellation Pharmaceuticals is a premier epigenetics company\, focused on the discovery and development of novel\, small molecules targeting chromatin regulatory proteins in tumor and immune cells for therapeutic applications in oncology. Our unique discovery platform integrates our understanding of chromatin-regulatory mechanisms with cancer and immune pathways to optimize our drug discovery activities and fully enable the clinical translation of our programs. Our translational capabilities are being currently expanded to ensure the differentiated clinical development of our clinical and pre-clinical assets and we look for talented and experienced individuals who want to participate in developing novel cancer therapeutics. \nResponsibilities: \n\nWork closely with scientists to design and execute cell-based phenotypic and mechanism of action assays in a variety of assay platforms\nGenerate\, analyze\, and catalog data with database tools such as Genedata and software tools such as GraphPad Prism\nPerform standard molecular biology and biochemistry techniques according to established protocols\nDocument all work in electronic notebooks and present data internally at group meetings\nRequirements: \n\nBS/MS in biology or other relevant field\nA minimum of 2-3 years of postgraduate laboratory experience (industry setting preferred)\nExperience with mammalian cell culture and standard molecular biology techniques is essential\nExperience with a variety of cell-based assays (Cell Titer Glo\, ELISA\, flow cytometry) is essential\nAbility to adapt to new roles in a dynamic working environment\, detail oriented with excellent time management skills\nStrong oral and written communication skills and an ability to successfully work as part of an integrated\, interdisciplinary team
URL:https://ces.b2sg.org/event/constellation-24feb18/
LOCATION:Constellation Pharmaceuticals\, 215 First Street\, Cambridge\, MA\, 02142\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180228
DTEND;VALUE=DATE:20180330
DTSTAMP:20260820T153959
CREATED:20180228T120457Z
LAST-MODIFIED:20180228T120546Z
UID:19719-1519776000-1522367999@ces.b2sg.org
SUMMARY:Assistant Scientist
DESCRIPTION:The Sylvester Cancer Center is seeking an Assistant Scientist for the Cancer Epigenetics to work in a highly collaborative\, multi-researcher program investigating the molecular mechanisms of epigenetic regulation of cancer.  \nResponsibilities: We are seeking highly motivated individuals to develop and implement innovative computational approaches for analyzing high throughput genomic and epigenomic data\, including but not limited to\, integrated cancer risk prediction model\, cancer subtype discovery\, genomic and epi-genomic data integration\, single cell RNA-Seq data analysis\, non-coding RNA data analysis\, and other datasets. Projects will include next-generation sequencing based profiling studies of DNA methylation\, hydroxymethylation\, ChIP-seq\, ATAC-seq and RNA-seq to elucidate the role of epigenetic regulation in cancer biology. Applicants should hold a PhD and/or MD degree and have strong computational biology skills. Previous experience with epigenome-wide assays is preferred. The successful candidate will be working in a collaborative environment with multiple faculty members\, biostatisticians and bioinformaticians on translational cancer research.  \nMinimum Qualifications: Ph.D. in Bioinformatics\, Computational Biology\, Biostatistics\, Statistics\, Genetics\, Computer Science\, or a related field. Excellent communications skills in English (both verbal and written). Proficiency in using R/Bioconductor and Perl/Python for genomic data analysis is required. Solid training in quantitative sciences. Experience with R/Bioconductor. Experience with Next-generation sequencing data analysis. Understanding of epigenome biology. Strong programming skills. Strong oral and written communication skills. The ability to work both independently and in a team environment. Ability to write manuscripts independently. 
URL:https://ces.b2sg.org/event/umiami-28feb18/
LOCATION:University of Miami\, 1320 S Dixie Hwy\, Coral Gables\, FL\, 33146\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180228
DTEND;VALUE=DATE:20180330
DTSTAMP:20260820T153959
CREATED:20180228T121528Z
LAST-MODIFIED:20180228T121915Z
UID:19721-1519776000-1522367999@ces.b2sg.org
SUMMARY:Informatics Analyst II
DESCRIPTION:This position will work primarily with scientists and computational experts using Next Generation Sequencing (NGS) data\, such as RNA-sequencing\, miRNA-sequencing\, and Methylation arrays. This position focuses on applied bioinformatics skills in transcriptional profiling and epigenetic analyses in pediatric acute myeloid leukemia. \nResponsibilities \nSpecific Responsibilities Include \n\nProcess diverse NGS datasets prior to analysis.\nImplement standard data quality\, formatting and annotation processes.\nData management and organization for large “omics” datasets ( > 1000 samples).\nVisualization of “omics” data.\nContribution to on-going research projects\, including statistical and bioinformatics support for clinical research fellows\, and molecular biologists.\n\nQualifications \nBasic Qualifications \n\nEnrollment in an accredited graduate degree program.\nAbility to commit to a 9-month\, full-time position.\nProgramming skills in R.\nProgramming skills in Python.\nExperience with computing in a Unix/Linux environment.\nExperience with high performance computing clusters (HPC) and job scheduling systems (SLURM\, Torque\, etc).\n\nAdditional Skills/Preferences \n\nStrong verbal\, written\, and organizational skills.\nAbility to work both independently and in a team.\nCoursework in molecular biology\, algorithms\, and statistics.
URL:https://ces.b2sg.org/event/hutch-28feb18/
LOCATION:Fred Hutchinson Cancer Research Center\, 1100 Fairview Ave. N.\, Seattle\, WA\, 98109-1024\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180228
DTEND;VALUE=DATE:20180330
DTSTAMP:20260820T153959
CREATED:20180228T124534Z
LAST-MODIFIED:20180325T093647Z
UID:19724-1519776000-1522367999@ces.b2sg.org
SUMMARY:Senior Principal Scientist\, Receptor Biochemist
DESCRIPTION:The Pfizer Oncology Research & Development group in La Jolla is seeking a full-time employee to support the drug discovery process to create innovative cancer therapies. The successful candidate will provide expert scientific and technical expertise towards the discovery and pre-clinical development of innovative small molecule drugs for receptor-class protein targets (e.g. GPCR\, NHR\, SLC). The successful candidate will work with a high degree of independence to provide biochemical insight on receptor targets and ligands as well as impact drug discovery project teams at a high strategic level. \nResponsibilities \n\nProvide senior\, strategic\, and technical leadership for the cellular and molecular characterization of receptor targets (GPCR\, nuclear hormone receptors\, membrane transporters\, and ion channels) and the development of effective lead discovery testing-cascades that impact the oncology portfolio and advance innovative drugs through our preclinical pipeline\nLead/ contribute to the establishment of methods to characterize and understand the impact of receptor drug candidates – particularly with regard to assessment of targeted receptor agonist/antagonist interactions (on-/off-target occupancy) and efficacy for multiple preclinical oncology projects\nLead/ contribute to the establishment of programs to identify relevant biomarkers for oncology receptor drug candidates\nDemonstrate strong leadership\, personal accountability and interpersonal skills\, and capability for mentoring junior colleagues (direct reports and others)\, and establish safe\, high-quality lab practices\nEnsure high-quality\, timely documentation in electronic laboratory notebooks and Technical Reports\, and contribute to Regulatory Filings and responses to Regulatory questions as appropriate\nPresent data/ strategy to scientists and management in internal and external venues (technical meetings\, Project Team meetings\, conferences) and publish in peer-reviewed journals\, as appropriate\nMaintain current in relevant literature and innovative technologies and their application to receptor target characterization and understanding\, particularly in areas of tumor cell receptor signaling\, epigenetics\, and immune-oncology\n\nQualifications \n\nThe candidate must have a Ph.D. in biochemistry or cell biology (or related field) with 8+ years of experience in small molecule drug discovery with a strong track record of success.\nThe individual will be a recognized scientific and technical expert with cellular receptors (e.g. GPCR\, NHR) and highly experienced in methods to characterize agonists and antagonists and their biochemical and cellular function/activities.\nA well-established ability to develop robust\, functional in vitro assays for the discovery of small molecule agonist/antagonists of membrane receptors is required.\nCorresponding or senior-authored publications in top-tier journals is also a prerequisite.\nThe candidate must demonstrate strong leadership\, personal accountability and interpersonal skills\, and capability for mentoring junior colleagues (direct reports and others)\, and establish safe\, high-quality lab practices.\nIn addition\, the candidate should display a strong strategic understanding of small molecule drug discovery and have a broad understanding of cross-discipline drug discovery processes within a project team.\nA scientific background in oncology and/or immuno-oncology drug discovery is preferred.\nThe candidate should possess excellent communication skills (written\, verbal)\, proven leadership skills\, and the demonstrated ability to make good decisions and influence teams to advance projects and navigate the complexities of receptor-based drug discovery.
URL:https://ces.b2sg.org/event/pfizer-28feb18/
LOCATION:Pfizer – Pearl River\, NY\, 401 North Middletown Road\, Pearl River\, NY\, 10965\, United States
CATEGORIES:Jobs
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180302
DTEND;VALUE=DATE:20180404
DTSTAMP:20260820T153959
CREATED:20180302T180057Z
LAST-MODIFIED:20180302T180355Z
UID:19728-1519948800-1522799999@ces.b2sg.org
SUMMARY:Institute Research Scientist - Translational Biology
DESCRIPTION:The Institute Research Scientist participates in cross-functional research to identify and validate novel oncology targets\, and applies deep biological insights to then translate these findings into novel oncology therapeutic agents to benefit patients.  \nSalary Range: Min $98\,000 – Mid $122\,500 – Max $147\,000  \nESSENTIAL FUNCTIONS  \n1. Apply and develop basic science tools and methodologies to develop complex strategies and enable advancement of Center projects through leadership and experimental activities.  \n2. Apply cutting edge functional genomics approaches to enable systematic investigation into mechanisms of tumorigenesis and drug resistance.  \n3. Independently design\, execute and interpret in vitro\, ex-vivo and in vivo experiments to validate and explore therapeutic potential of drug targets.  \n4. Work with research and bioinformatics teams to utilize internal biological and oncogenomic data sets to generate and test biological hypotheses.  \n5. Work with medicinal chemistry and pharmacology teams as part of drug discovery efforts to validate targets and optimize novel small molecule therapeutics.  \n6. Lead drug discovery biology efforts to selection of lead candidate molecules and transition into clinical development.  \n7. Develop and implement biomarker strategies to guide early clinical development of drugs.  \n8. Design and develop cell and molecular assays to define mechanism of action for compounds\, identify pharmacodynamic assays to be used in pre-clinical and clinical setting and test patient selection strategies.  \n9. Develop extensive knowledge and experience in key areas of tumor biology including\, but not limited to oncogenic signaling\, tumor microenvironment\, tumor immunology\, metabolism\, epigenetic deregulation or apoptosis.  \n10. Adapt to new technologies and find solutions to related program studies.  \n11. Interpret\, present and report research findings at internal meetings and external scientific conferences.  \nEducation  \nRequired: Bachelor’s degree in Biology\, Biochemistry\, molecular biology\, cell biology\, enzymology\, pharmacology\, chemistry or related field.  \nPreferred: PhD in Biological Science or Medical degree strongly preferred  \nExperience  \nRequired: Ten years of relevant research laboratory experience. With Master’s degree\, eight years of required experience and with PhD\, two years of required experience.  \nPreferred: At least two years of relevant experience in oncology research in biotech or pharmaceutical environment.  \n– Experience with genetic (ie RNAi and cDNAs) and pharmacological (i.e. small molecule inhibitors or antibodies) approaches to study target biology utilizing state of the art molecular biology and biochemistry methods and assays essential to drive projects.  \n– Experience working with chemists\, in vitro and in vivo pharmacologists to develop and utilize assays in support of the development of small molecules for target validation and as part of compound lead optimization for the development of novel therapeutics is highly desirable.  \n– A demonstrated track record in the development and implementation of functional genomics strategies to enable systematic investigation into mechanisms of tumorigenesis and drug resistance.  \n– Broad knowledge of cell culture techniques is required and knowledge of how to utilize in vivo oncology models is desirable. Hands-on experience utilizing genetically engineered mouse models and orthotopic or subcutaneous primary or established tumor cell line xenograft models is desirable.  \n– Extensive knowledge and experience in key areas of tumor biology including\, but not limited to oncogenic signaling\, tumor microenvironment\, tumor immunology\, metabolism\, epigenetic deregulation or anti-apoptosis as evidenced by publication in peer-reviewed journals.  \n– Strong data analysis skills\, ability to interpret results and contribute to the design of follow-up experiments\, troubleshoot issues with assay performance\, and effectively present results and conclusions to co-workers\, collaborators and senior leadership.
URL:https://ces.b2sg.org/event/mda-2mar18/
LOCATION:MD Anderson Cancer Center\, 1515 Holcombe Blvd\, Houston\, TX\, 77030\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180303
DTEND;VALUE=DATE:20180405
DTSTAMP:20260820T153959
CREATED:20180303T191059Z
LAST-MODIFIED:20180303T191059Z
UID:19731-1520035200-1522886399@ces.b2sg.org
SUMMARY:Research Associate
DESCRIPTION:USC’s Keck School of Medicine\, Department of Pathology\, Southern California Research Center for ALPD and Cirrhosis\, is seeking a Research Associate to join its team to pursue cutting-edge research on NIH-funded project(s) pertaining to cellular\, molecular\, and metabolic mechanisms of liver inflammation\, fibrosis\, and cancer. The incumbent will productively engage in cellular\, molecular and metabolic mechanisms of liver inflammation\, fibrosis\, and cancer with primary focus on epigenetic reprogramming and activation/reactivation of hepatic stellate cells and alcoholic liver fibrosis leading to publication and federal grant applications.  \nThe candidate must be able to communicate both verbally and in writing to maintain sound scientific communications with colleagues on and off-campus. The Research Associate plans\, designs and conducts highly technical and complex research projects independently and in consultation with supervisor. The Research Associate analyzes research data and provides interpretations; contributes to the development of research documentation for publication and/or prepares technical reports\, papers and/or records.  \nThe applicant must have a Ph.D. or equivalent degree in cell and molecular biology and a minimum of 3 to 4 years basic science experiences in cell and molecular biology. The Keck School of Medicine Department of Pathology is one of the largest pathology departments in the United States. The Department aims to shape the future of pathology as it will be practiced in community hospitals\, academic medical centers and clinical laboratories throughout the country. The position offers a competitive salary with excellent university benefits. This is a grant-funded position.  \n\nMinimum Education: Ph.D. or equivalent doctorate \nMinimum Experience: 1 year \nMinimum Field of Expertise: Directly related education and experience in research specialization with advanced knowledge of equipment\, procedures and analysis methods.
URL:https://ces.b2sg.org/event/usc-3mar18/
LOCATION:University of Southern California\, Los Angeles\, CA\, 90007\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180303
DTEND;VALUE=DATE:20180405
DTSTAMP:20260820T153959
CREATED:20180303T192448Z
LAST-MODIFIED:20180303T192449Z
UID:19733-1520035200-1522886399@ces.b2sg.org
SUMMARY:Research Fellow - Cancer Biology
DESCRIPTION:Postdoctoral positions are available in the Department of Cancer Biology to understand the biology of cancer stem cells\, cancer progression and metastasis. We use molecular biology\, biochemical and mouse modeling approaches to dissect the role of posttranslational modifications\, such as protein ubiquitination and methylation in signaling pathways\, metabolism\, cancer immunity\, epigenetics and DNA damage response and their potential applications for cancer drug development. 
URL:https://ces.b2sg.org/event/wfbh-3mar18/
LOCATION:Wake Forest Baptist Health\, Winston-Salem\, NC\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180303
DTEND;VALUE=DATE:20180406
DTSTAMP:20260820T153959
CREATED:20180303T193121Z
LAST-MODIFIED:20180303T193121Z
UID:19739-1520035200-1522972799@ces.b2sg.org
SUMMARY:Postdoc Fellow - Cancer Biology (Myeloma)
DESCRIPTION:Translational Development at Celgene is pleased to present a growth opportunity for outstanding post-doctoral fellows with a passion for hematology-oncology research and clinical development towards improved outcomes in myeloma patient healthcare. The multiple myeloma Translational Development team currently employs state of the art platforms and analytics to address the most important questions that will drive the current and next generation of therapeutic development for myeloma patients. \nThe successful candidate will become part of diverse team with a unified bench-to-bedside vision in precision healthcare and diagnostic approaches to biomarker utilization. The overarching goal of the successful candidate will be to provide\, through passionate research efforts\, clinically implementable information to better understand how patient characteristics\, malignancy biology and immune context features align to define patient outcomes from treatment with portfolio therapeutics and enable rationale combo design. This fellowship will work alongside top shelf scientists with deep knowledge of myeloma disease biology and further expertise including genomic definition of risk and outcomes\, immune characterization\, definition of response and tumoral evolution using single cell platforms and lab-based screens to better understand mechanistics of clinically-observed phenomenon. \nSkills/Knowledge Required: \n\nPhD in cancer biology\, genetics\, epigenetics\nStrong background in disease or mechanism based studies using modern experimental and computational methods is required.\nKnowledge of myeloma is desirable but not required.\nExperience in heme malignancy related areas\nWhile understanding of epigenetics and epigenetic experimental approaches are not essential\, it is highly desirable.\nPrior experience in molecular\, cellular\, functional and computational methods\nAbility to formulate experimental ideas\nDemonstrated writing and commutation skills\nAbility work in a collaborative team science environment
URL:https://ces.b2sg.org/event/celgene-3mar18/
LOCATION:Celgene\, 86 Morris Ave\, Summit\, NJ\, 07901\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180304
DTEND;VALUE=DATE:20180406
DTSTAMP:20260820T153959
CREATED:20180304T093152Z
LAST-MODIFIED:20180304T093152Z
UID:19743-1520121600-1522972799@ces.b2sg.org
SUMMARY:Postdoctoral Associate
DESCRIPTION:A postdoctoral associate position is available in the laboratory of Dr. Jennifer Trowbridge at The Jackson Laboratory in Bar Harbor\, Maine to study epigenetic mechanisms governing hematopoietic stem cell lineage commitment\, and how deregulation of epigenetic modifications leads to myeloproliferative disorders including leukemia. ( http://trowbridgelab.com )  \nThe Jackson Laboratory (JAX) offers a unique research and training environment characterized by multidisciplinary scientific collaboration\, unparalleled mouse resources\, outstanding core services\, and is located adjacent to Acadia National Park in coastal Bar Harbor\, Maine. Translational research collaborations in genomics-based\, personalized medicine are fostered through our new JAX Genomic Medicine campus in Farmington\, CT. In addition to lab-based training\, JAX has developed a unique program for trainees to expand their professional skills in science communication\, entrepreneurship\, teaching\, mentoring and laboratory management to best prepare postdocs for future career opportunities.  \nRequired Skills  \nAssociate must be able to plan\, execute and analyze an independent research project\, as well as exceptional verbal and written communication skills. Preference given to self-motivated and career oriented individuals.  \nRequired Experience  \nA Ph.D. in biological or related sciences is required\, and a strong training background in molecular biology\, cell biology and/or epigenetics is preferred.
URL:https://ces.b2sg.org/event/jax-4mar18/
LOCATION:Jackson Laboratory\, 600 Main Street\, Bar Harbor\, ME\, 04609\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180304
DTEND;VALUE=DATE:20180406
DTSTAMP:20260820T153959
CREATED:20180304T093837Z
LAST-MODIFIED:20180304T093837Z
UID:19745-1520121600-1522972799@ces.b2sg.org
SUMMARY:Postdoctoral Fellow
DESCRIPTION:Position Summary and Key Responsibilities:\nPostdoctoral position: Characterizing cancer progression and metastasis  \nTo develop and characterize solid cancer model systems in order to study epigenetic changes contributing to cancer progression and metastasis. These models will aid in the discovery of promising targets and evaluation of treatment strategies. The overall goal of these pre-clinical studies will be to provide supporting data for the potential clinical translation of novel\, effective therapeutic approaches.  \nPlease include CV with publication record and (if applicable) previous/current grant funding.  \nMinimum Education and Skills Required for Consideration:\nPh.D. with emphasis in oncology and/or epigenetics\, but will also consider biochemistry\, immunology or microbiology background with experience in cancer or epigenetics research.  \nExperience in flow cytometry is preferred  \nMouse handling with proficiency in different routes of injection.  \nStrong critical thinking skills and ability to troubleshoot. 
URL:https://ces.b2sg.org/event/hope-4mar18/
LOCATION:City of Hope\, 1500 East Duarte Road\, Duarte\, 91010\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180304
DTEND;VALUE=DATE:20180406
DTSTAMP:20260820T153959
CREATED:20180304T123009Z
LAST-MODIFIED:20180304T123047Z
UID:19747-1520121600-1522972799@ces.b2sg.org
SUMMARY:Postdoctoral Scientist
DESCRIPTION:Come work for an organization where everything matters. \nSummary:\nWorks under the mentorship of Dr. Stephen Lessnick\, the Director of the Center for Childhood Cancer and Blood Diseases at Nationwide Children’s Hospital Research Institute (NCHRI). Dr. Lessnick’s laboratory is focused on the molecular basis of Ewing sarcoma development\, with a particular emphasis on the transcriptional and epigenetic functions of the EWS/FLI fusion oncogenic transcription factor. The successful applicant will have basic skills in molecular biology and tissue culture\, but will also bring and apply new areas of expertise to the laboratory. Of particular interest are individuals with expertise any of the following areas: biochemistry\, biophysics\, epigenetics\, transcriptional analysis\, computation biology\, etc. The successful applicant will have an early track-record of publication success\, will be able to work independently and develop collaborations as-needed\, and will also mentor junior trainees\, technicians\, and others in the lab. \nResponsibilities:\nWith guidance from a CRI mentor\, design experiments and develops protocols required to conduct productive research in a specific scientific area. After the study has been designed\, performs the research work in accordance with the protocol. \nHelps to train and supervise technical support staff in performing specific techniques essential to carrying out the research program. \nRecords and analyzes data generated by the research study\, and helps to plan future research endeavors. \nPrepares scientific and technical papers from the results of the research work. Publishes papers in appropriate refereed scientific journals. Presents findings at local (particularly CRI research meetings) and national research forums. \nIf appropriate\, collaborates with other ongoing research efforts either at CRI or at The Ohio State University. \nThis is considered a training position therefore the RI will allow a trainee 5 years to advance beyond the level of Post Doc. \nWorks toward research independence. Prepares to submit proposals to and obtain funding from external granting agencies. \nOther information:\nREPORTING RELATIONSHIPS\nReports to: Either established CRI principal investigator (i.e. OSU faculty member) or a CRI Senior Research Scientist for guidance in research endeavors \nKNOWLEDGE \, SKILLS AND ABILITIES REQUIRED\nMD\, Ph.D\, Pharm.D.\, or equivalent degree in PhD in Molecular Biology\, Biochemistry\, or Biomedical Sciences\, Cellular and Molecular Biology\, Biophysics\, Bioinformatics \n2. Necessary technical skills in the appropriate area of research. \n3. Ability to do technical writing\, and good communication skills.
URL:https://ces.b2sg.org/event/nchri-4mar18/
LOCATION:Nationwide Children’s Hospital Research Institute\, 700 Children's Dr\, Columbus\, OH\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180305
DTEND;VALUE=DATE:20180407
DTSTAMP:20260820T153959
CREATED:20180305T075636Z
LAST-MODIFIED:20180305T075636Z
UID:19756-1520208000-1523059199@ces.b2sg.org
SUMMARY:Research Investigator
DESCRIPTION:We are seeking a highly motivated bioinformatician to join our Translational Bioinformatics Immunoscience (IMS) and Small Molecule Immuno-Oncology (smIO) team. The successful candidate will help advance Bristol-Myers Squibb’s industry leading IMS and IO pipelines through the strategic application of cutting edge bioinformatics approaches. This team interacts with and influences all aspects at BMS from early discovery through development. \nResponsibilities \nAnalyze various -omic-scale data including RNA-Seq\, Exome and Whole Genome Sequencing\, single cell sequencing\, high throughput proteomics\, and multiplex flow cytometry in order to nominate novel drug targets\, enable patient enrichment strategies\, and prioritize combination therapies. \nIntegrate and mine large-scale external data sets (GEO\, TCGA\, 1KG\, EXAC\, Cosmic) to further our understanding of autoimmune diseases and cancer pathogenesis. \nCollaborate with bioinformaticians\, statisticians and biologists to implement and execute bioinformatics and statistical analysis plans. \nQualifications: \n\nPh.D. in bioinformatics\, engineering\, statistics\, physics\, molecular biology\, genetics\, or a similar discipline.\nStrong background in -omic (DNA\, RNA\, epigenetic\, proteomic) data analysis and biological interpretation\nSolid background in Immunoscience and/or Immuno-Oncology biology.\nAbility to communicate effectively with biologists\, biostatisticians and computational scientists.\nProficiency using R and Bioconductor packages\, at least one scripting language (Python\, Perl)\, and SQL.\nExperience working with Linux high performance compute clusters and cloud based computing platforms (Amazon EC2).\nWorking knowledge of commercial and publicly available biological databases including NCBI\, Ensembl\, ArrayExpress/GEO\, SRA\, TCGA and 1000 Genomes is expected.\nFluency in NGS experiments and data analysis (e.g. GATK\, Cufflinks\, SAMtools\, BAMtools etc.) is preferred.\nExperience working with data from clinical trials is a plus.
URL:https://ces.b2sg.org/event/bms-5mar18/
LOCATION:Bristol-Myers Squibb\, Princeton\, NJ\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180308
DTEND;VALUE=DATE:20180410
DTSTAMP:20260820T153959
CREATED:20180308T175951Z
LAST-MODIFIED:20180308T181236Z
UID:19760-1520467200-1523318399@ces.b2sg.org
SUMMARY:Postdoctoral Fellowship - Genetics\, Epigenetic Regulation
DESCRIPTION:Positions of two postdoctoral scientistsare open now in the Chen laboratory ( https://www.cityofhope.org/faculty/jianjun-chen ). Our group is interested in discovering novel genetic and epigenetic regulations and deciphering their underlying molecular mechanisms in normal developmental processes (e.g.\, hematopoiesis) and tumorigenesis (e.g.\, leukemogenesis). We cover research areas with relevance to Hematology\, Immunology\, and Cancer Biology\, with an emphasis on RNA epigenetics (mainly focusing on the N 6 methyladenosine (m 6 A) modification) and DNA epigenetics (mainly focusing on the TET1/2/3-mediated DNA demethylation) associated basic and translational research. Our research involves experiments with primary human cancer cells\, cancer and stem cell transplantation models\, mouse genetics\, classic molecular\, biochemistry and cell biology\, functional genomics\, signal transduction\, and large-scale data analysis and computational biology.  \nMinimum Education and Skills Required for Consideration:\nThe candidates for the Postdoctoral scientist positions should have a Ph.D. and/or M.D. degree(s)\, and a solid background in biochemistry\, mouse model studies\, hematology\, epigenetics\, immunology\, pathology\, and/or stem cell research is preferred for. The candidates should not have more than three years of postdoc training experience. The candidates should be highly motivated individuals with the ability to work in a team environment and with good oral and written communication skills in English.  \nApplication:\nPlease apply to this job posting. Additionally\, your application\, including CV\, brief motivation statement\, and contact information of three scientific mentors (references)\, should be saved as a single PDF. The PDF file can be sent to Dr. Jianjun Chen ( jianchen@coh.org ) directly. 
URL:https://ces.b2sg.org/event/hope-8mar18/
LOCATION:City of Hope\, 1500 East Duarte Road\, Duarte\, 91010\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180308
DTEND;VALUE=DATE:20180410
DTSTAMP:20260820T153959
CREATED:20180308T181000Z
LAST-MODIFIED:20180308T181000Z
UID:19762-1520467200-1523318399@ces.b2sg.org
SUMMARY:Postdoctoral Associate - Cancer Epigenetics
DESCRIPTION:The Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine has an exciting opportunity for a Postdoctoral Associate in the Cancer Epigenetics Program. This position will work in a highly collaborative environment investigating the molecular mechanisms of epigenetic regulation of leukemia and normal hematopoiesis.  \nSpecifically\, we are seeking a highly motivated Postdoctoral Associate with in-depth knowledge and extensive skills in cellular and molecular biology to join the lab. The Postdoctoral Associate should demonstrate expertise in various laboratory techniques including cell culture and molecular biology assays (molecular cloning\, cell proliferation assay\, subpopulation analysis by FACS\, stable and transient transfection\, use of shRNA and viral constructs)\, preparation and analysis of DNA and RNA (preparation of plasmids\, regular PCR and RT-PCR)\, chromatin immunoprecipitation (ChIP) assays\, biochemical assays (ELISA\, immunoblotting\, Co-IP). Prior experience in epigenetics in preferred but not required. Prior experience in hematopoiesis/leukemia models\, molecular biology\, cancer genetics or epigenetics\, and/or development of animal models is required. It is expected that the Postdoctoral Associate will have the ability to work independently\, design experiments with appropriate controls\, collect and tabulate data\, publish and present results\, as well as to participate in the training of graduate and rotation students in a research laboratory setting. Projects will include in vivo and in vitro modeling of candidate genes to identify epigenetically silenced genes that contribute to the development of hematopoietic malignancies and characterization of candidate genes using in vitro and in vivo systems.  \nThe minimum qualifications for this position are as follows: Ph.D. and/or M.D. with strong molecular biology or cancer biology skills. Previous experience with epigenetics\, cancer modeling or hematopoiesis is preferred. Evidence of scholarly ability (record of publication in peer-reviewed journals\, etc.) must be presented. Ability to communicate in written and spoken English is required. The Postdoctoral Associate will be working in a collaborative environment that includes wet bench cancer biologists and computational biologists. 
URL:https://ces.b2sg.org/event/umiami-8mar18/
LOCATION:University of Miami\, 1320 S Dixie Hwy\, Coral Gables\, FL\, 33146\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180309
DTEND;VALUE=DATE:20180411
DTSTAMP:20260820T153959
CREATED:20180309T171506Z
LAST-MODIFIED:20180309T171506Z
UID:19765-1520553600-1523404799@ces.b2sg.org
SUMMARY:Postdoctoral Scientist
DESCRIPTION:JOB SUMMARY: Working independently but in close cooperation and in consultation with the Principal Investigator and other Research Scientist\, the Research Fellow will perform routine and complex laboratory procedures throughout training period. May develop\, adapt\, and implement new research techniques and protocols. Analyzes and interprets data. May assist in preparation of grant proposals. Participates in publications and presentations as author or co-author. Not responsible for generating grant funds.  \nESSENTIAL JOB DUTIES AND RESPONSIBILITIES: May assist in preparation of grant proposals\, but is not responsible for generating grant funds. May participate in publications and presentations as author or co-author. Designs and performs experiments. Will keep appropriate experimental records and documentation and analyze the results with the Principal Investigator. May develop\, adapt\, and implement new research techniques and protocols. Analyzes\, interprets\, summarizes and compiles data. Performs routine and complex laboratory procedures throughout training period. Operates and maintains equipment and instruments.  \nDEPARTMENT AND/OR UNIT SPECIFIC – ESSENTIAL JOB RESPONSIBILITIES: The Postdoctoral Scientist investigates mechanisms of progenitor cell expansion in the healthy lung and in lung cancer. Projects include defining genetic and epigenetic mechanisms that regulate progenitor cell renewal versus differentiation and how this changes in the setting of lung cancer. Experimental approaches employed in the laboratory include disease modeling using genetically modified mice\, prospective isolation and cultivation of lung stem cells\, isolation and culture of human lung epithelial cells from patient-derived samples and advanced genomics approaches for single cell gene expression profiling and epigenetic analysis.  \nQualification Requirements/Preferences:\nEducation Certifications/Licensure Experience Physical Abilities Educational Requirements:\nDoctorate (MD\, PhD\, VMD\, or DDS) in area directly related to field of research specialization. \nExperience:\nWorks independently on research projects designed by a mentor (typically the PI) within area of specialization. Acquires thorough technical and theoretical knowledge of research project and objectives during one to five (1-5) year post-doctoral appointment. Demonstrated aptitude to perform experimental protocols and procedures\, including detailed data collection\, and analysis and operation and maintenance of specialized equipment. Knowledge of safety standards and maintenance of specialized equipment.
URL:https://ces.b2sg.org/event/cedars-9mar18/
LOCATION:Cedars-Sinai Medical Center\, Los Angeles\, 8700 Beverly Blvd\, Los Angeles\, CA\, 90048\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180309
DTEND;VALUE=DATE:20180411
DTSTAMP:20260820T153959
CREATED:20180309T173033Z
LAST-MODIFIED:20180309T173238Z
UID:19767-1520553600-1523404799@ces.b2sg.org
SUMMARY:Postdoctoral Associate - Cancer Research
DESCRIPTION:The laboratory of Dr. Enrique Mesri at the University of Miami Miller School of Medicine’s Department of Microbiology and Immunology and the Tumor Biology Program of Sylvester Comprehensive Cancer Center\, in collaboration with a multidisciplinary team led by Dr. Michael Samuels of the Department of Radiation Oncology\, has an exciting opportunity for a Postdoctoral Associate with relevant experience. This position will lead a project evaluating key viral\, genomic\, and epigenetic correlates of clinical presentation and outcomes of HPV-associated oropharynx cancer. Work includes\, but is not limited to\, analysis of tumor samples and biological fluids derived from ongoing clinical studies.  \nThe minimum qualifications for this position are as follows: Ph.D.\, M.D.\, or other doctoral level degree in a related field of life science study. Possess a strong background and first author publication(s) in cancer biology\, virology\, molecular and cellular biology\, or a closely related field of study. Prefer experience working with cell\, animal\, or clinical models in virally induced human cancers. Applicants with experience\, or who are familiar with bioinformatic tools (particularly next generation sequencing data analysis)\, are encouraged to apply. Must be goal-oriented\, proactive\, and hardworking with excellent organizational skills and a passion for making a difference in cancer research. Ability to manage day-to-day operations of the laboratory\, mentoring new staff\, and assisting senior researchers in their presentation and funding efforts. A highly motivated individual is sought who can work effectively in a team as well as independently. Applicants should upload a CV when applying that contains a cover letter\, references\, and complete list of publications\, including representative publications as part of the CV. 
URL:https://ces.b2sg.org/event/umiami-9mar18/
LOCATION:University of Miami\, 1320 S Dixie Hwy\, Coral Gables\, FL\, 33146\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180310
DTEND;VALUE=DATE:20180412
DTSTAMP:20260820T153959
CREATED:20180310T070429Z
LAST-MODIFIED:20180310T070706Z
UID:19770-1520640000-1523491199@ces.b2sg.org
SUMMARY:Postdoctoral Research Associate - Bone Marrow Transplant
DESCRIPTION:  \nA postdoctoral scholar position in the area of Genomics and Bioinformatics is available in the laboratory of Dr. Christopher Maher at The McDonnell Genome Institute at Washington University School of Medicine in St. Louis. Our lab focuses on developing computational methods for analyzing large-scale cancer genomics data collections from solid tumors to improve our understanding of cancer biology and identify novel therapies for treating patients. Active projects address topics such as structural variation\, cancer evolution\, discovery and characterization of novel long non-coding RNAs\, and the development of new bioinformatics tools. \nPRIMARY DUTIES & RESPONSIBILITIES: \n\nEvaluation and design of experimental plans for sequencing-based projects studying the genetic basis of cancer.\nImplementation and development of automated pipelines to analyze high throughput sequencing data.\nIntegration of genetic and epigenetic changes in cancer including mutations\, gene expression data\, epigenetic modification\, copy number and structural variation.\nIntegrated pathway and gene network analysis related to cancer.\nAnalyze and interpret results to communicate with others and produce scientific publications is required.\n\n\n\n\n\n\n\nApplicants should have a graduate degree in biology\, bioinformatics\, computational biology\, or related field with a solid background in programming and statistics.
URL:https://ces.b2sg.org/event/wustl-10mar18/
LOCATION:Washington University School of Medicine in St. Louis\, 660 S Euclid Ave\, St. Louis\, MO\, 63110\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180310
DTEND;VALUE=DATE:20180412
DTSTAMP:20260820T153959
CREATED:20180310T094946Z
LAST-MODIFIED:20180310T094946Z
UID:19775-1520640000-1523491199@ces.b2sg.org
SUMMARY:Research Associate -Neurosurgery
DESCRIPTION:The Yun laboratory studies multiple aspects of cancer stem cell biology\, employing techniques in genetics\, genomics\, molecular biology\, cell biology\, and biochemistry. We are currently focusing on understanding mechanisms that promote cancer stem cell survival and self-renewal in medulloblastomas and glioblastomas (GBMs). We use genetically defined mouse models\, patient derived xenografts\, and primary human and mouse cancer stem cell cultures. Ongoing projects include: 1) elucidating molecular mechanisms of therapy resistance in brain cancer stem cells\, 2) developing new inhibitors to target cancer stem cells\, 3) developing a new experimental platform for drug testing\, 4) interrogation of epigenetic changes in stem cells\, 5) role of cancer stem cells in tumor immune modulation.  \nWe are looking for a postdoctoral fellow with a strong background in cancer biology\, stem cell biology\, tissue engineering\, pharmacology\, immunology or epigenetics.  \nHouston Methodist Research Institute (HMRI) is a non-profit\, academic research institute affiliated with the Weill Cornell Medical College and provides unique translational research opportunities. HMRI is located in the Texas Medical Center\, adjacent to Rice University\, Baylor College of Medicine\, and MD Anderson Cancer Center\, providing ample opportunities to interact with researchers in these neighboring institutions. We work hard and play hard and love what we do. We are looking for colleagues with demonstrated passion for science\, strong work ethics\, and excellent interpersonal and organizational skills.  \nApplications should include a CV\, names of three references\, and a cover letter describing research interest and background. Please send to: \nKyuson Yun\, Ph.D. \nEmail: kyun@houstonmethodist.org 
URL:https://ces.b2sg.org/event/hmri-10mar18/
LOCATION:Houston Methodist Research Institute\, 6670 Bertner Ave\, Houston\, TX\, 77030\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180310
DTEND;VALUE=DATE:20180412
DTSTAMP:20260820T153959
CREATED:20180310T100009Z
LAST-MODIFIED:20180310T100009Z
UID:19777-1520640000-1523491199@ces.b2sg.org
SUMMARY:Postdoc
DESCRIPTION:The successful candidate will work within a successful multidisciplinary research team that applies both computational and laboratory techniques to understand mechanisms responsible for epigenetic dysfunction in cancer. This project will have a particular emphasis on the use of assays to interrogate structural rearrangements and perform functional studies. We wish to use existing genomic data to inform laboratory experiments performing Hi-C to examine topologically associated domains (TADs) and their relationship to frequent translocations in myeloma including those involving the immunoglobulin loci and MYC. ChIP-seq and CRISPR/Cas9 experience or enthusiasm to develop new protocols would be advantageous\, in order to determine functionality of discovered abnormalities. There will be a component of computational analysis which will be performed in association with our bioinformatics team. \n\n\n\nResponsibilities\n\n\n\n(60%) – Design\, execute and interpret experiments to investigate the extent of DNA rearrangements\, topological domains and chromatin modifications in myeloma. \n(10%) – Maintain accurate and up-to-date records to document the research progress. \n(10%) – Take a lead role in writing up data for publication in peer-reviewed journals. \n(15%) – Interact with bioinformaticians and instruct in data analysis and summarization. \n(5%) – Present data ag group and section meetings. \n(5%) – Contribute to the dissemination of research at national and international meetings (annually) \nEstablish and maintain knowledge relevant to epigenetics\, genomics and biology of multiple myeloma (ongoing) \nMay perform other duties as assigned. \n\n\n\nQualifications\n\n\n\nPhD in Molecular biology\, genetics or oncology required. \nSalary: Negotiable \nUAMS is an inclusive Affirmative Action and Equal Opportunity Employer of individuals with disabilities and protected veterans and is committed to excellence.
URL:https://ces.b2sg.org/event/uams-10mar18/
LOCATION:Private: University of Arkansas for Medical Sciences\, 4301 W Markham St\, Little Rock\, AR\, 72205\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180310
DTEND;VALUE=DATE:20180412
DTSTAMP:20260820T153959
CREATED:20180310T130034Z
LAST-MODIFIED:20180310T130237Z
UID:19780-1520640000-1523491199@ces.b2sg.org
SUMMARY:Postdoc Fellow - Microbiology and Cancer
DESCRIPTION:Post Doctoral Fellow positions are available in the laboratory of Dr. Matthew Weitzman\, at the Children’s Hospital of Philadelphia (CHOP) and the University of Pennsylvania (Penn). Our lab is part of the rich scientific environment on the CHOP/Penn campus that includes multiple areas of virology\, immunology\, cancer\, and epigenetics. We are located in the new Colket Translational Research Building as part of the Division of Cancer Pathobiology\, in the Department of Pathology & Laboratory Medicine. The lab is also part of the Center for Childhood Cancer Research (CCCR)\, the Center for Cellular & Molecular Therapeutics (CCMT)\, the Penn Institute for Immunology (IFI)\, the Penn Epigenetics program\, and Penn Center for AIDS Research (CFAR). \nThe lab’s research focuses on virus-host interactions and the use of viruses as model systems to study DNA repair\, signaling\, cell biology\, replication\, innate host defenses and gene delivery. We are interested in virus replication and the resulting cellular responses. We study the intersection of virus and host pathways during infection and how they reveal insights into fundamental cellular mechanisms. We are particularly interested in recognition and processing of viral genomes by DNA repair and APOBEC pathways. We are using virus systems to study signaling\, ubiquitination and degradation\, and transcriptional silencing. Viral model systems include adeno-associated virus (AAV)\, adenovirus (Ad) and herpes simplex virus (HSV). \nJob Responsibilities \n\nConduct independent scholarly research and develop new methods and protocols\nParticipate in project planning\, recording and evaluation of data\nAcquire technical\, lab management and grant writing skills\nParticipate in seminars\, lectures\, poster sessions and presentation at national meetings\nSupervise junior lab members\nAssist with other research projects\n\nRequired Education and Experience \n\nA terminal degree PhD\, MD\, DVM\, etc.\nAccording to the CMS (Centers for Medicaid and Medicare Services) a copy of diploma or transcript is required as proof of academic achievement for all non-laboratory personnel performing non-waived POC testing
URL:https://ces.b2sg.org/event/chop-10mar18/
LOCATION:Children’s Hospital of Philadelphia\, 3401 Civic Center Blvd\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180310
DTEND;VALUE=DATE:20180412
DTSTAMP:20260820T153959
CREATED:20180310T132108Z
LAST-MODIFIED:20180310T132239Z
UID:19783-1520640000-1523491199@ces.b2sg.org
SUMMARY:Research Assistant I
DESCRIPTION:This position is security-sensitive and subject to Texas Education Code 51.215\, which authorizes UT Southwestern to obtain criminal history record information \nExperience and Education  \nMaster’s degree with major coursework in Biology or related fields\, and no experience required. \nBachelor’s degree with major coursework in Biology or related fields\, and one (1) year research experience at level of Research Technician or equivalent. \nTwo (2) years college with emphasis in coursework in field of assignment and four (4) years research experience including two (2) years at level of Research Technician or equivalent. \nHigh school graduation or GED and six (6) years research experience to include two (2) years at level of Research Technician or equivalent. \nShould have knowledge of basic molecular biology\, biochemistry and/or genetics. \nShould also have training in animal husbandry and PCR genotyping. \nJob Duties  \nA Research Assistant I position is available in the lab of Dr. Jian Xu in Children’s Research Institute. Our lab focuses on the intersection of gene regulation with stem cell biology\, hematopoiesis and cancer. \nWe employ epigenetics\, functional genomics\, genome editing\, biochemistry\, and mouse genetics to define epigenetic programs that control blood stem cell development\, and how these processes go awry in cancer progression. \nPrinciple Responsibilities: \nManage a multi-line mouse colony. This includes breeding\, genotyping animals and maintaining the database. \nPrepare and maintain tissue and cell cultures\, flow cytometry and other assays. \nContribute to lab organizational matters such as ordering supplies\, maintaining stocks and overseeing equipment. \nSecondary Responsibilities: \nPerforms more difficult scientific and medical research work in science area such as biology\, chemistry\, physics\, or other related scientific field. \nConstructs\, assembles\, and operates laboratory equipment and apparatus. \nRecords and evaluates data obtained from work assignments for use in scientific papers. \nCollaborates with supervisor or other research personnel in preparation of scientific papers for publication. \nReads literature and confers with supervisor concerning procedures and implementation. \nCollects and organizes research data for project reports. \nMay plan for\, and provide working supervision to\, work of Research Technicians or other laboratory personnel of lower grade.
URL:https://ces.b2sg.org/event/uts-10mar18/
LOCATION:UT Southwestern Medical Center\, 5323 Harry Hines Blvd.\, Dallas\, TX\, 75390\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180313
DTEND;VALUE=DATE:20180415
DTSTAMP:20260820T153959
CREATED:20180313T085840Z
LAST-MODIFIED:20180313T085905Z
UID:19786-1520899200-1523750399@ces.b2sg.org
SUMMARY:Research Fellow
DESCRIPTION:The Arthanari Lab is seeking for a highly motivated postdoctoral candidate with expertise in transcriptional biology. Our laboratory works at the interface of structural biology\, drug discovery and mechanistic biology\, focusing on transcription factors and there interactions with co-activators and mediators (e.g. Nature. 201625;530(7591):485-9 ; Nature 2008. 452 (7187): 604-9) .Research efforts will be focused on the intersection of cancer biology/genetics and immune-oncology. \n\n\n\nQualifications\n\n\n\nThe candidate is expected to have a comprehensive understanding of signaling pathways\, epigenetics and transcription regulation. Experience in technical skills including cell culture\, somatic genetic analysis (e.g.\, CRISPr\, si\, sh RNA knockdown and rescue)\, protein biochemistry\, assay design and development and biological applications to advance discovery are preferred. The individual should be independent and passionate about science and have an established record of creativity\, ability to work in teams and strong publication record in peer-reviewed scientific journals.
URL:https://ces.b2sg.org/event/df-13mar18/
LOCATION:Dana-Farber Cancer Institute\, 450 Brookline Avenue\, Boston\, MA\, 02215\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180313
DTEND;VALUE=DATE:20180415
DTSTAMP:20260820T153959
CREATED:20180313T124847Z
LAST-MODIFIED:20180313T124939Z
UID:19788-1520899200-1523750399@ces.b2sg.org
SUMMARY:Research Associate
DESCRIPTION:To enable Guardant Health to lead the disruption of cancer treatments through non-invasive cancer screening\, the Technology Development Team is seeking a highly motivated Research Associate to help develop\, test\, and improve sample preparation technologies for rare variant and epigenetic studies with next-generation sequencing. At Guardant\, we leverage the most advanced technologies and work with leaders in many different fields to create the most impactful and meaningful technologies for cancer management. \nAs a Research Associate supporting product and technology development\, you will work with members within the team and interface with multiple teams including process engineering\, clinical operations\, research operations\, and bioinformatics. You will be hands on in the lab and be required to design\, implement\, and validate new technologies related to liquid biopsy sequencing assays for the early detection\, treatment\, and monitoring of all cancer types. \nRESPONSIBILITIES \n\nOperate next generation sequencing instruments\nRun sequencing sample preparation assays in medium to high throughput environment\nTest and improve new sequencing sample preparation assays\nLog and track research samples throughout sequencing workflow\nMaintain appropriate inventory of lab supplies\nBring a can-do attitude to solve new and challenging problems in a high pace environment\nAnalyze data and troubleshoot issues within the tech dev team and among other teams\nCollaborate with all functions within project teams\nEngage in early design of products and perform experiments both independently and under the supervision of Senior team members within Tech Dev and Bioinformatics groups\nCan present updates\, write reports and SOPs\, and contribute to technical discussions\n\nQualifications \nABOUT YOU \n\nThe ability to handle biological samples (i.e. tissue\, bio-fluid\, etc.) is a must\nExcellent written and oral communication skills is a must\nProfessional hands-on experience in industrial setting in genomics field is a plus (operational experience is preferred)\nHands-on experience in running sequencing platforms and assays is a plus
URL:https://ces.b2sg.org/event/guardant-13mar18/
LOCATION:Guardant Health\, 505 Penobscot Dr.\, Redwood City\, CA\, 94063\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/05/guardant-health.jpg
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180314
DTEND;VALUE=DATE:20180416
DTSTAMP:20260820T153959
CREATED:20180314T135933Z
LAST-MODIFIED:20180314T140319Z
UID:19794-1520985600-1523836799@ces.b2sg.org
SUMMARY:Postdoctoral Fellow 0 - Inflammation & Epigenetics
DESCRIPTION:Performs basic research duties under the supervision/direction of a Physician (Principal Investigator). We are seeking two highly-motivated researchers or postdoctoral fellows (1) to study the biology of Chimeric Antigen Receptor (CAR) T and NK cells\, (2) to develop innovative CAR-T and CAR-NK cells for infectious diseases and cancer with the ultimate goal of administering them to patients as part of a future clinical trial (NIH funded); and (3) to study the cell biology and immunology of NK cell\, with a focus on NK cell inhibitory receptor signaling and immunological synapse. We are using molecular\, biochemical\, and imaging strategies\, as well as cutting-edge biophysical approaches for understanding human lymphocyte dysfunction in chronic infectious diseases and cancers.  \nAll applicants with experience in molecular biology/cloning\, immunology\, cancer biology\, infectious diseases\, and imaging are encouraged to apply. This post-doctoral fellowship or research position will provide the opportunity to apply super-resolution imaging techniques to study the biology of cytotoxic lymphocytes and CAR cells in the laboratory of Dongfang Liu\, Ph.D.  \nPlease send your application\, a cover letter\, and statement of career goals\, CV\, and contact information for 3 references to:\nDongfang Liu\, Ph.D. \nEmail: dliu2@houstonmethodist.org  \nPATIENT AGE GROUP SERVED \nNot applicable  \nDUTIES AND RESPONSIBILITIES  \n\nDevelops research methods and performs research activities. (EF)\nDocuments research results and writes reports of results for presentation and/or publication in professional journals and other publications. (EF)\nAssists in maintaining the functionality and operations of the Principal Investigator’s laboratory. (EF)\nDemonstrates the components of the I CARE values. (EF)\nFollows all safety rules while on the job. Reports accidents promptly and corrects minor safety hazards. Communicates with peers and management regarding any hazards identified in the workplace. (EF)\nPerforms other duties as assigned by the Principal Investigator.\n\nEDUCATION REQUIREMENTS \nM.D. or Ph.D required  \nEXPERIENCE REQUIREMENTS \nExperience requirements will vary depending on the field of research. \nPostdoctoral Fellow 0– no Postdoc experience required \nPostdoctoral Fellow 1– one year of Postdoc experience \nPostdoctoral Fellow 2 – two years of experience \nPostdoctoral Fellow 3 – three years of postdoc experience \nPostdoctoral Fellow 4 – four years of postdoc experience 
URL:https://ces.b2sg.org/event/hmri-14mar18/
LOCATION:Houston Methodist Research Institute\, 6670 Bertner Ave\, Houston\, TX\, 77030\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/06/houston-methodist-e1498136597133.jpg
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180314
DTEND;VALUE=DATE:20180416
DTSTAMP:20260820T153959
CREATED:20180314T141909Z
LAST-MODIFIED:20180314T141909Z
UID:19797-1520985600-1523836799@ces.b2sg.org
SUMMARY:Research Assistant Scientist
DESCRIPTION:The Division of Genetic Epidemiology in the Department of Epidemiology is recruiting a non-tenure track Research Assistant Scientist in genetic epidemiology of human complex diseases. The position will focus on identifying genetic\, epigenetic or metabolic factors for cardiovascular disease\, diabetes\, obesity\, mental illness\, Alzheimer’s disease or related conditions. The candidate will have opportunities to work on rich high-dimensional omics datasets\, e.g.\, GWAS\, WGS\, EWAS\, RNA-seq\, metabolomics\, and proteomics datasets.  \nThe candidate should have a PhD in epidemiology\, quantitative genetics\, bioinformatics or a related field. Preference will be given to the candidate who has strong computer skills (e.g.\, programming languages\, quantitative genetic methods\, and familiarity with UNIX-like operating systems) and excellent English writing skills. Experience with handling massive omics datasets and publications in genetic epidemiology are preferred\, but not required. The candidate should have a strong interest in genetic epidemiology\, be highly motivated to conduct scientific research\, be able to work independently in team-oriented projects\, and be consistent\, responsible and accurate in scientific research. Of note\, this position is only for applications that have a strong background in quantitative genetics\, bioinformatics\, and programming ability in genetic epidemiology research. Those who would like to work in a wet lab should not apply for this position . Starting salary will be commensurate with training and experience.  \nThe Department of Epidemiology ( http://epidemiology.phhp.ufl.edu/ ) is situated jointly within the College of Public Health and Health Professions (PHHP) and College of Medicine (COM)\, in the Clinical and Translational Research Building\, facilitating multidisciplinary research. Faculty members pursue independent and collaborative research; they teach in the MS and PhD in Epidemiology Programs\, the Master of Public Health Program\, and also teach first and second year medical students. They are advisors and mentors to a wide variety of students. Our current faculty members are leaders in genetic epidemiology\, aging\, cancer\, cardiac\, chronic disease\, environmental\, infectious\, substance abuse\, and psychiatric epidemiology. The Department works closely with the NIH-funded Clinical and Translational Science Institute and is home to HealthStreet\, and a Fogarty International Center Training Grant and multiple NIH and other grants. The Department provides an outstanding environment for interdisciplinary\, cutting-edge scientific research\, and interactions with other units that perform basic\, translational and clinical research. Minorities are strongly encouraged to apply. 
URL:https://ces.b2sg.org/event/ufl-14mar18/
LOCATION:University of Florida\, Gainesville\, FL\, 32611\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/06/uni-florida.jpg
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180315
DTEND;VALUE=DATE:20180417
DTSTAMP:20260820T153959
CREATED:20180315T123642Z
LAST-MODIFIED:20180315T123836Z
UID:19799-1521072000-1523923199@ces.b2sg.org
SUMMARY:Research Intern
DESCRIPTION:A full-time position as a Research Intern is available in Dr. Jennifer Trowbridge’s lab\, focusing on stem cell biology in blood system aging and blood cancer. This position will involve conducting basic\, hypothesis-driven research on hematopoietic stem cells and leukemia stem cells to understand the mechanisms governing stem cell self-renewal\, differentiation and how deregulation of epigenetic modifications leads to leukemia. See https://www.trowbridgelab.com for more details about our research efforts and current team members. \nThe Research Intern position is a temporary\, mentored position lasting up to 36 months and is designed specifically for individuals with a 4 year Life Science\, Biology or applicable degree looking to advance their scientific/research training prior to pursuing further education (graduate-level or medical degree). During the internship\, Interns are eligible to apply for permanent positions at JAX as long as performance is rated satisfactory by their Scientific Advisor\, but a permanent position is not guaranteed. \nKey Responsibilities: \n\nExpand subject matter expertise through investigation of the primary literature towards effective study design and independent research project leadership.\nSuccessful execution of complex tests\, experiments and procedures in the context of a larger study design; and ability to recognize and implement quality control measures where needed.\nData analysis and design of data documentation / reporting; leads efforts to modify and adapt research methodologies; ensures compliance with regulatory standards.\nPreparation of research reports\, literature reviews\, scientific papers\, and/or assistance with drafting and generating preliminary data for research proposals in consultation with the Principal Investigator; develops and delivers presentations at lab meetings as well as to the larger Laboratory community and external scientific community.\nOperate and troubleshoot highly specialized equipment.\n\n\nRequired Skills \n\nBachelor’s degree in life sciences\, biological sciences or related discipline.\nPrevious experience in an academic setting performing experiments\, interpreting and evaluating results\, and compiling data preferred.\nExplicit interest in pursuing and completing eligibility requirements for continuing studies in biomedical research or in pursuing a medical degree.\nThe ability to work in a demanding\, fast paced\, team-oriented environment\, while maintaining a high-level of professionalism.\nAbility to develop technical documents and presentations.\nAbility to work flexible shifts (evening/week-end/holiday).\n\nA cover letter outlining general interests\, and career goals should be submitted with CV/Resume as one document to consider application complete.
URL:https://ces.b2sg.org/event/jax-15mar18/
LOCATION:Jackson Laboratory\, 600 Main Street\, Bar Harbor\, ME\, 04609\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/07/jackson.jpg
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