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METHOD:PUBLISH
X-WR-CALNAME:Cancer Epigenetics Society
X-ORIGINAL-URL:https://ces.b2sg.org
X-WR-CALDESC:Events for Cancer Epigenetics Society
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TZID:Europe/Paris
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TZOFFSETFROM:+0100
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TZNAME:CEST
DTSTART:20180325T010000
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DTSTART:20181028T010000
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180313
DTEND;VALUE=DATE:20180415
DTSTAMP:20260821T095127
CREATED:20180313T085840Z
LAST-MODIFIED:20180313T085905Z
UID:19786-1520899200-1523750399@ces.b2sg.org
SUMMARY:Research Fellow
DESCRIPTION:The Arthanari Lab is seeking for a highly motivated postdoctoral candidate with expertise in transcriptional biology. Our laboratory works at the interface of structural biology\, drug discovery and mechanistic biology\, focusing on transcription factors and there interactions with co-activators and mediators (e.g. Nature. 201625;530(7591):485-9 ; Nature 2008. 452 (7187): 604-9) .Research efforts will be focused on the intersection of cancer biology/genetics and immune-oncology. \n\n\n\nQualifications\n\n\n\nThe candidate is expected to have a comprehensive understanding of signaling pathways\, epigenetics and transcription regulation. Experience in technical skills including cell culture\, somatic genetic analysis (e.g.\, CRISPr\, si\, sh RNA knockdown and rescue)\, protein biochemistry\, assay design and development and biological applications to advance discovery are preferred. The individual should be independent and passionate about science and have an established record of creativity\, ability to work in teams and strong publication record in peer-reviewed scientific journals.
URL:https://ces.b2sg.org/event/df-13mar18/
LOCATION:Dana-Farber Cancer Institute\, 450 Brookline Avenue\, Boston\, MA\, 02215\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180313
DTEND;VALUE=DATE:20180415
DTSTAMP:20260821T095127
CREATED:20180313T124847Z
LAST-MODIFIED:20180313T124939Z
UID:19788-1520899200-1523750399@ces.b2sg.org
SUMMARY:Research Associate
DESCRIPTION:To enable Guardant Health to lead the disruption of cancer treatments through non-invasive cancer screening\, the Technology Development Team is seeking a highly motivated Research Associate to help develop\, test\, and improve sample preparation technologies for rare variant and epigenetic studies with next-generation sequencing. At Guardant\, we leverage the most advanced technologies and work with leaders in many different fields to create the most impactful and meaningful technologies for cancer management. \nAs a Research Associate supporting product and technology development\, you will work with members within the team and interface with multiple teams including process engineering\, clinical operations\, research operations\, and bioinformatics. You will be hands on in the lab and be required to design\, implement\, and validate new technologies related to liquid biopsy sequencing assays for the early detection\, treatment\, and monitoring of all cancer types. \nRESPONSIBILITIES \n\nOperate next generation sequencing instruments\nRun sequencing sample preparation assays in medium to high throughput environment\nTest and improve new sequencing sample preparation assays\nLog and track research samples throughout sequencing workflow\nMaintain appropriate inventory of lab supplies\nBring a can-do attitude to solve new and challenging problems in a high pace environment\nAnalyze data and troubleshoot issues within the tech dev team and among other teams\nCollaborate with all functions within project teams\nEngage in early design of products and perform experiments both independently and under the supervision of Senior team members within Tech Dev and Bioinformatics groups\nCan present updates\, write reports and SOPs\, and contribute to technical discussions\n\nQualifications \nABOUT YOU \n\nThe ability to handle biological samples (i.e. tissue\, bio-fluid\, etc.) is a must\nExcellent written and oral communication skills is a must\nProfessional hands-on experience in industrial setting in genomics field is a plus (operational experience is preferred)\nHands-on experience in running sequencing platforms and assays is a plus
URL:https://ces.b2sg.org/event/guardant-13mar18/
LOCATION:Guardant Health\, 505 Penobscot Dr.\, Redwood City\, CA\, 94063\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180314
DTEND;VALUE=DATE:20180416
DTSTAMP:20260821T095127
CREATED:20180314T135933Z
LAST-MODIFIED:20180314T140319Z
UID:19794-1520985600-1523836799@ces.b2sg.org
SUMMARY:Postdoctoral Fellow 0 - Inflammation & Epigenetics
DESCRIPTION:Performs basic research duties under the supervision/direction of a Physician (Principal Investigator). We are seeking two highly-motivated researchers or postdoctoral fellows (1) to study the biology of Chimeric Antigen Receptor (CAR) T and NK cells\, (2) to develop innovative CAR-T and CAR-NK cells for infectious diseases and cancer with the ultimate goal of administering them to patients as part of a future clinical trial (NIH funded); and (3) to study the cell biology and immunology of NK cell\, with a focus on NK cell inhibitory receptor signaling and immunological synapse. We are using molecular\, biochemical\, and imaging strategies\, as well as cutting-edge biophysical approaches for understanding human lymphocyte dysfunction in chronic infectious diseases and cancers.  \nAll applicants with experience in molecular biology/cloning\, immunology\, cancer biology\, infectious diseases\, and imaging are encouraged to apply. This post-doctoral fellowship or research position will provide the opportunity to apply super-resolution imaging techniques to study the biology of cytotoxic lymphocytes and CAR cells in the laboratory of Dongfang Liu\, Ph.D.  \nPlease send your application\, a cover letter\, and statement of career goals\, CV\, and contact information for 3 references to:\nDongfang Liu\, Ph.D. \nEmail: dliu2@houstonmethodist.org  \nPATIENT AGE GROUP SERVED \nNot applicable  \nDUTIES AND RESPONSIBILITIES  \n\nDevelops research methods and performs research activities. (EF)\nDocuments research results and writes reports of results for presentation and/or publication in professional journals and other publications. (EF)\nAssists in maintaining the functionality and operations of the Principal Investigator’s laboratory. (EF)\nDemonstrates the components of the I CARE values. (EF)\nFollows all safety rules while on the job. Reports accidents promptly and corrects minor safety hazards. Communicates with peers and management regarding any hazards identified in the workplace. (EF)\nPerforms other duties as assigned by the Principal Investigator.\n\nEDUCATION REQUIREMENTS \nM.D. or Ph.D required  \nEXPERIENCE REQUIREMENTS \nExperience requirements will vary depending on the field of research. \nPostdoctoral Fellow 0– no Postdoc experience required \nPostdoctoral Fellow 1– one year of Postdoc experience \nPostdoctoral Fellow 2 – two years of experience \nPostdoctoral Fellow 3 – three years of postdoc experience \nPostdoctoral Fellow 4 – four years of postdoc experience 
URL:https://ces.b2sg.org/event/hmri-14mar18/
LOCATION:Houston Methodist Research Institute\, 6670 Bertner Ave\, Houston\, TX\, 77030\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/06/houston-methodist-e1498136597133.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180314
DTEND;VALUE=DATE:20180416
DTSTAMP:20260821T095127
CREATED:20180314T141909Z
LAST-MODIFIED:20180314T141909Z
UID:19797-1520985600-1523836799@ces.b2sg.org
SUMMARY:Research Assistant Scientist
DESCRIPTION:The Division of Genetic Epidemiology in the Department of Epidemiology is recruiting a non-tenure track Research Assistant Scientist in genetic epidemiology of human complex diseases. The position will focus on identifying genetic\, epigenetic or metabolic factors for cardiovascular disease\, diabetes\, obesity\, mental illness\, Alzheimer’s disease or related conditions. The candidate will have opportunities to work on rich high-dimensional omics datasets\, e.g.\, GWAS\, WGS\, EWAS\, RNA-seq\, metabolomics\, and proteomics datasets.  \nThe candidate should have a PhD in epidemiology\, quantitative genetics\, bioinformatics or a related field. Preference will be given to the candidate who has strong computer skills (e.g.\, programming languages\, quantitative genetic methods\, and familiarity with UNIX-like operating systems) and excellent English writing skills. Experience with handling massive omics datasets and publications in genetic epidemiology are preferred\, but not required. The candidate should have a strong interest in genetic epidemiology\, be highly motivated to conduct scientific research\, be able to work independently in team-oriented projects\, and be consistent\, responsible and accurate in scientific research. Of note\, this position is only for applications that have a strong background in quantitative genetics\, bioinformatics\, and programming ability in genetic epidemiology research. Those who would like to work in a wet lab should not apply for this position . Starting salary will be commensurate with training and experience.  \nThe Department of Epidemiology ( http://epidemiology.phhp.ufl.edu/ ) is situated jointly within the College of Public Health and Health Professions (PHHP) and College of Medicine (COM)\, in the Clinical and Translational Research Building\, facilitating multidisciplinary research. Faculty members pursue independent and collaborative research; they teach in the MS and PhD in Epidemiology Programs\, the Master of Public Health Program\, and also teach first and second year medical students. They are advisors and mentors to a wide variety of students. Our current faculty members are leaders in genetic epidemiology\, aging\, cancer\, cardiac\, chronic disease\, environmental\, infectious\, substance abuse\, and psychiatric epidemiology. The Department works closely with the NIH-funded Clinical and Translational Science Institute and is home to HealthStreet\, and a Fogarty International Center Training Grant and multiple NIH and other grants. The Department provides an outstanding environment for interdisciplinary\, cutting-edge scientific research\, and interactions with other units that perform basic\, translational and clinical research. Minorities are strongly encouraged to apply. 
URL:https://ces.b2sg.org/event/ufl-14mar18/
LOCATION:University of Florida\, Gainesville\, FL\, 32611\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180315
DTEND;VALUE=DATE:20180417
DTSTAMP:20260821T095127
CREATED:20180315T123642Z
LAST-MODIFIED:20180315T123836Z
UID:19799-1521072000-1523923199@ces.b2sg.org
SUMMARY:Research Intern
DESCRIPTION:A full-time position as a Research Intern is available in Dr. Jennifer Trowbridge’s lab\, focusing on stem cell biology in blood system aging and blood cancer. This position will involve conducting basic\, hypothesis-driven research on hematopoietic stem cells and leukemia stem cells to understand the mechanisms governing stem cell self-renewal\, differentiation and how deregulation of epigenetic modifications leads to leukemia. See https://www.trowbridgelab.com for more details about our research efforts and current team members. \nThe Research Intern position is a temporary\, mentored position lasting up to 36 months and is designed specifically for individuals with a 4 year Life Science\, Biology or applicable degree looking to advance their scientific/research training prior to pursuing further education (graduate-level or medical degree). During the internship\, Interns are eligible to apply for permanent positions at JAX as long as performance is rated satisfactory by their Scientific Advisor\, but a permanent position is not guaranteed. \nKey Responsibilities: \n\nExpand subject matter expertise through investigation of the primary literature towards effective study design and independent research project leadership.\nSuccessful execution of complex tests\, experiments and procedures in the context of a larger study design; and ability to recognize and implement quality control measures where needed.\nData analysis and design of data documentation / reporting; leads efforts to modify and adapt research methodologies; ensures compliance with regulatory standards.\nPreparation of research reports\, literature reviews\, scientific papers\, and/or assistance with drafting and generating preliminary data for research proposals in consultation with the Principal Investigator; develops and delivers presentations at lab meetings as well as to the larger Laboratory community and external scientific community.\nOperate and troubleshoot highly specialized equipment.\n\n\nRequired Skills \n\nBachelor’s degree in life sciences\, biological sciences or related discipline.\nPrevious experience in an academic setting performing experiments\, interpreting and evaluating results\, and compiling data preferred.\nExplicit interest in pursuing and completing eligibility requirements for continuing studies in biomedical research or in pursuing a medical degree.\nThe ability to work in a demanding\, fast paced\, team-oriented environment\, while maintaining a high-level of professionalism.\nAbility to develop technical documents and presentations.\nAbility to work flexible shifts (evening/week-end/holiday).\n\nA cover letter outlining general interests\, and career goals should be submitted with CV/Resume as one document to consider application complete.
URL:https://ces.b2sg.org/event/jax-15mar18/
LOCATION:Jackson Laboratory\, 600 Main Street\, Bar Harbor\, ME\, 04609\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180316
DTEND;VALUE=DATE:20180418
DTSTAMP:20260821T095127
CREATED:20180316T082412Z
LAST-MODIFIED:20180316T082517Z
UID:19802-1521158400-1524009599@ces.b2sg.org
SUMMARY:Postdoc - Immune Oncology
DESCRIPTION:Position Highlights:  \n\nIndividuals in this position will participate in ongoing laboratory and clinical studies to define mechanisms and impact of epigenetic agents on immunotherapy response. Studies will include in-depth mechanistic approaches to define underlying molecular mechanisms\, as well as studies in mouse models of lung cancer and patient clinical samples. \n\nThe Ideal Candidate:  \n\nWill have a strong background in immunology and familiarity with basic immunological assays such as flow cytometry. \nPreference will be given to those who have recently graduated with a Ph.D. degree.\n\nResponsibilities:  \n\nIndividuals in this position are expected to work under minimal supervision and who are capable of independently designing and executing experimental work. \n\nCredentials and Qualifications:  \n\nPh.D. or M.D. in Immunology or related field. 
URL:https://ces.b2sg.org/event/moffitt-16mar18/
LOCATION:Moffitt Cancer Center Magnolia Campus\, 12902 USF Magnolia Drive\, Tampa\, FL\, 33612\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/05/Moffitt-1.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180316
DTEND;VALUE=DATE:20180418
DTSTAMP:20260821T095127
CREATED:20180316T164608Z
LAST-MODIFIED:20180316T164636Z
UID:19804-1521158400-1524009599@ces.b2sg.org
SUMMARY:Post Doc Fellow – Structural Biology & Drug Discovery
DESCRIPTION:Position Highlights:  \n\nWe seek highly motivated postdoctoral researchers to work on inter-disciplinary projects towards the characterization and inhibitor development of diverse kinases and bromodomain-containing proteins. \nThe position provides exciting opportunities for biochemical\, structural and cell-based studies of various drug-target interactions and rational drug design. \n\nThe Ideal Candidate:  \n\nThe ideal candidate has a Ph.D. degree in Biochemistry\, Biology\, Chemistry\, Physics or related field and expertise in protein crystallography and biochemistry as demonstrated by publications in internationally recognized scientific journals. \nAdditional experience in cell biology is preferred. \n\nResponsibilities:  \n\nCandidates must be enthusiastic and dedicated to science with excellent organizational skills and effective at working independently\, while also collaborating and assisting the team in its collective research goals. \nAttention to detail and ability to work on multiple projects is required. \nExcellent verbal and written communication skills are required. \n\nCredentials and Qualifications:  \n\nPh.D. degree in Biochemistry\, Biology\, Chemistry\, Physics or related field 
URL:https://ces.b2sg.org/event/moffitt2-16mar18/
LOCATION:Moffitt Cancer Center Magnolia Campus\, 12902 USF Magnolia Drive\, Tampa\, FL\, 33612\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180317
DTEND;VALUE=DATE:20180420
DTSTAMP:20260821T095127
CREATED:20180317T185744Z
LAST-MODIFIED:20180317T185744Z
UID:19806-1521244800-1524182399@ces.b2sg.org
SUMMARY:Postdoc Research Associate
DESCRIPTION:Postdoctoral associate positions available for highly motivated candidates with a fresh PHD training in molecular biology\, cell biology or biochemistry to join the Lineberger Comprehensive Cancer Center\, University of North Carolina at Chapel Hill (UNC) School of Medicine\, USA. The lab (Webpage: http://www.gregwanglab.com) emphasizes on mechanistic understandings of gene regulation\, chromatin\, stem cells\, and human disease\, notably cancer (see our recent publications at Molecular Cell 2013\, Blood 2015\, Cell Reports 2015; Cancer Cell 2016). Multiple on-going projects include (1) biochemical characterization of epigenetic factors/complexes that regulate gene expression in stem cells or cancer cells; (2) CRISPR/dCas9-based editing and screening of epigenetic pathways in gene expression; (3) knockout and knock-in mouse models with deficiency in histone methylation regulation in context of development and tumorigenesis\, with a special focus on hematopoietic cancer and disease; (4) epigenomic and transcriptome analyses (ChIP-Seq and RNA-Seq) of normal versus cancer cells to delineate pathways essential for tumor growth.\n\n\n\n\n\nMinimum Qualifications:\nApplicants should be self-motivated with a track record of publication in the above area\, have laboratory and analytical skills\, and be a critical thinker. Application shall include CV\, a cover letter (with summary of research experiences and future interests\, and expected availability date) reprints of publications\, and contact information of three referees.  PHD training in molecular biology\, cell biology or biochemistry related field.
URL:https://ces.b2sg.org/event/unc-17mar18/
LOCATION:University of North Carolina – UNC-Chapel Hill\, Chapel Hill\, NC\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180317
DTEND;VALUE=DATE:20180420
DTSTAMP:20260821T095127
CREATED:20180317T193228Z
LAST-MODIFIED:20180317T193228Z
UID:19808-1521244800-1524182399@ces.b2sg.org
SUMMARY:Research Fellow
DESCRIPTION:A Research Fellow position is available in the program of Dr. Keith Robertson. For more information about Dr. Robertson’s program\, please see: http://www.mayo.edu/research/faculty/robertson-keith-d-ph-d/bio-20035097 \nThe successful candidate will join the Epigenetic Etiology of Human Disease Laboratory to study the role of DNA epigenetic modifications in human disease. More specifically\, he/she will examine how DNA methylating and hydroxymethylating enzymes regulate their respective DNA epigenetic modifications and how these marks modulate expression and genome stability\, and interface with other epigenetic modifications. Disease focus areas of the laboratory include cancer (hepatocellular and renal)\, obesity\, and diabetes. Specific research areas include application of genome-wide epigenomics methods to decipher DNA methylation/hydroxymethylation defects in cancer and biochemical/cell culture-based techniques to study the regulation and interactions between chromatin remodeling factors (e.g. DNMTs\, TETs\, HMTases) and the roles of their target loci in driving disease. Techniques commonly used in the laboratory include: quantitative RT-PCR\, western blotting\, cell culture\, transfections\, bisulfite sequencing\, DNA immunoprecipitation\, pyrosequencing\, ChIP-qPCR\, ChIP-seq\, next-gen library preparation and sequencing\, Infinium 850k arrays\, bioinformatics analysis\, microscopy\, and biochemical analysis of protein function. Experience in one or more of these areas is a plus. The candidate will play a major role in the preparation of manuscripts that arise from this work and devote 100% effort to these tasks (no patient contact or other responsibilities). \nPosition description \nA Research Fellow at Mayo Clinic is a temporary position intended to provide training and education in research. Individuals will train in the research program of a Mayo Clinic principal investigator. Qualified individuals will demonstrate the potential for research as evidenced by their training and peer-reviewed publications and should become competitive for national research grants. Proof of English proficiency is required for J-1 Short-Term Scholars\, Research Scholars\, Professors\, Specialists\, and Student Interns sponsored by Mayo Clinic. 800146; J2WRTP \nQualifications \nMust have a Ph.D.\, M.D.\, or equivalent doctoral degree in a field deemed relevant by the program. Research Fellow is appropriate for individuals who have completed no more than one prior postdoctoral fellowship\, at Mayo Clinic or elsewhere. Please attach the following required documents at the time of application: \n\n\nCurrent curriculum vitae and bibliography\nThree letters of recommendation\, signed\, on letterhead\, describing:\n\n\n\nRelationship to the applicant.\nPast work/academic performance.\nWork qualities/personal conduct.\nOverall assessment of potential for success in research environment.\n\n\nDoctoral degree certification\, if applicable:\nOriginal or notarized copy of diploma or final transcript issued by school (English translation required).
URL:https://ces.b2sg.org/event/mayo-17mar18/
LOCATION:Mayo Clinic\, 200 1st St SW\, Rochester\, MN\, 55905\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180322
DTEND;VALUE=DATE:20180424
DTSTAMP:20260821T095127
CREATED:20180322T093847Z
LAST-MODIFIED:20180322T094520Z
UID:19810-1521676800-1524527999@ces.b2sg.org
SUMMARY:Quantitative Image Analyst - Immuno-oncology
DESCRIPTION:We seek a highly motivated quantitative Image Analyst to be part of a larger inter-disciplinary team that focuses on target discovery\, validation and biomarker research in immune-oncology. The successful candidate should have deep knowledge of image analysis methods and know how to apply them towards a better understanding of tumor immune microenvironment in response to various immunotherapies. The image analyst will work closely with immunologists\, biologists\, computational biologists and translational oncologists\, to support a diverse set of research programs and should enjoy operating in a highly dynamic and cooperative environment. The candidate should have the ability to work independently and come up with quick\, robust and creative computational tissue image analysis solutions to various research goals. \nRole Responsibilities \n\nUtilize and develop cutting edge image analysis techniques that accurately QC\, segment\, register\, and quantify digital histopathology images\, to understand spatial changes in the tumor immune microenvironment and ultimately predict biomarkers in response to various cancer immunotherapies.\nPerform morphological immunophenotyping of tumors using deep understanding of statistical and predictive modeling concepts\, machine-learning approaches including but not limited to deep learning\, clustering and classification techniques\, and image segmentation strategies\nQuantify and interpret highly multiplex immunofluorescent images on tissue samples from preclinical models and human subjects\, to define the phenotype\, functionality\, and localization of immune and other cells within complex tissue types in both 2D and 3D settings.\nDevelop innovative algorithmic and statistical approaches to integrate diverse datasets (IHC/IF images\, FACS/cyTOF\, RNA-seq\, DNA-seq\, epigenetics) from preclinical models and clinical trials to identify targets\, biomarkers\, resistance mechanisms of current therapies\, and predict effective therapeutic combinations\nBe up-to-date on state-of-the-art methods and techniques in computational image analysis and provide support on an as-needed basis to cross-disciplinary project teams\n\nQualifications \nEducation and Experience \n\nPhD in Bioinformatics/Computational Biology\, Immunology\, Mathematics\, Statistics\, Biostatistics or closely related field with 8+ years of post-PhD experience with substantial expertise in using advanced computational image analysis platforms for image processing\, analysis\, and visualization across various tissue architectures\nProven record of scientific rigor and scientific success\nAbility to work effectively on teams and good team player attitude required\nExcellent communication skills (oral and written) as demonstrated by publications & presentations\nAbility to multi-task and project prioritization required\n\nTechnical Skill Requirements \n\nExperience in applying and developing state-of the-art image analysis techniques and methods on images from latest immunohistochemistry techniques (multiplex IF/IHC\, ISH) across various tissue architectures.\nAbility to categorize and analyze data sets via neural networks and associated deep learning technologies (including but not limited to TensorFlow library) facilitating quantitative processing and interpretation of highly multiplex immunofluorescent images\nAbility to identify and discern patterns and insights within structured and unstructured data.\nAbility to work closely with bench scientists to troubleshoot and solve potential imaging artifacts\nExcellent programming experience in machine learning and deep learning (C++\, Python/Perl\, R\, Matlab)\nAuthorship demonstrating the application of image analysis in high quality publications\n\nPreferred Qualifications \n\nDemonstrated understanding of biology (specifically immunology) desirable\nExperience in analysis of large-scale genomic data such as RNA-seq\, Exome-seq\, whole-genome seq\, ChIP-Seq\, genotype\, microarrays and flow/mass cytometry desirable\nProficiency in developing web-based applications and ability to code in Java desirable
URL:https://ces.b2sg.org/event/pfizer-22mar18/
LOCATION:Pfizer – Pearl River\, NY\, 401 North Middletown Road\, Pearl River\, NY\, 10965\, United States
CATEGORIES:Jobs
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180322
DTEND;VALUE=DATE:20180424
DTSTAMP:20260821T095127
CREATED:20180322T100626Z
LAST-MODIFIED:20180322T100626Z
UID:19812-1521676800-1524527999@ces.b2sg.org
SUMMARY:Staff Research Associate I/II
DESCRIPTION:JOB OVERVIEW\nUnder direct supervision and with training provided\, the Staff Research Associate II (SRA II) will provide research assistance for the Munster Laboratory in the Division of Hematology/Oncology\, Department of Medicine. The research program in the Munster laboratory focuses on the epigenetic modulation of therapy resistance\, with a focus on improving treatments for breast and other cancers.  \nDEPARTMENT OF MEDICINE\nThe Department of Medicine\, with annual revenues of $417 million\, is the largest department in the UCSF School of Medicine. The mission of the Department is research (basic and clinical)\, teaching\, patient care\, and public service.  \nABOUT UCSF \nThe University of California\, San Francisco (UCSF) is a leading university dedicated to promoting health worldwide through advanced biomedical research\, graduate-level education in the life sciences and health professions\, and excellence in patient care. It is the only campus in the 10-campus UC system dedicated exclusively to the health sciences. \n\n\nRequired Qualifications \n• BA/BS degree in a immunology or related science and one or more years of recent\, directly related work experience following degree completion\, utilizing the techniques or methods required by the position; or an equivalent combination of education and experience\n• Experienced in processing samples for and conducting multi-parameter flow cytometry\n• Ability to analyze data in spreadsheets\, data entry into databases\, database management\, advanced computer skills\n• Ability to draft routine reports and keep accurate records of work performed \n• Strong inclination to learn and apply new techniques\n• Ability to handle and prioritize responsibilities pertaining to multiple projects \n\n\nPreferred Qualifications \n• Understanding and research experience in the field of immunology\n• Experience handling and working with human tissues\n• Experience purifying PBMCs from blood\n• Experience in assisting team members\n• Coursework experience with nucleic acid amplification\, PCR\, cloning\n• General cell culture technique. Serial passage of cells\, transfection\, growth assays
URL:https://ces.b2sg.org/event/ucsf-22mar18/
LOCATION:UCSF\, 505 Parnassus Ave\, San Francisco\, CA\, 94143\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180322
DTEND;VALUE=DATE:20180424
DTSTAMP:20260821T095127
CREATED:20180322T102038Z
LAST-MODIFIED:20180322T102038Z
UID:19814-1521676800-1524527999@ces.b2sg.org
SUMMARY:Clinical Research Scientist
DESCRIPTION:This position is responsible for working with the physicians and cross functions within Clinical Development to provide clinical research support for programs as assigned by phase. \nResponsibilities \nIn collaboration with cross functional teams performs the following: \n\nDevelops protocols and informed consent documents for clinical studies\nAnalyzes and works with clinical data\nDrafts clinical scientific documents such as IND\, IND amendments\, Investigator Brochures\, and other documents for FDA/EMA submissions\nContributes actively in the CSR preparation and finalization\nMonitors\, & reviews along with the medical monitor safety and efficacy data in ongoing studies; monitors GCP compliance with help of clinical operations and CRO\nContributes to the development of CRFs\nAnswers along with the medical monitor patient eligibility questions from CRO and site and questions from IRB/EC and health authorities\nMay have a leadership role in the matrix teams for assigned compounds\nDevelops and maintains relationships with appropriate KOLs\, investigators\, cooperative groups\, and patient advocacies. Serves as first point of contact for medical questions from sites\nAssists and/or writes with clinical abstracts\, assists and/or presents data at scientific meetings\, SIVs; conducts protocol training\nParticipates with clinical operations in the CRO/vendor selection and bidding\nKeeps abreast of oncology treatment modalities\, drug mechanism of action\, approaches to drug development and regulatory requirements\nActs as a clinical representative in variety of cross-functional teams\n\nQualifications \n\nDegree in scientific/life-sciences/clinical/nursing field. M.S.\, Ph.D. preferred\nPrior hematology or oncology drug development experience is highly desired\nAbility to multi-task well\, to deal well with conflict and obstacles\, and to work in a fast-paced environment\nExcellent written and oral communication skills\nStrong analytical ability
URL:https://ces.b2sg.org/event/epizyme-22mar18/
LOCATION:Epizyme\, 400 Technology Square\, Cambridge\, MA\, 02139\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180323
DTEND;VALUE=DATE:20180425
DTSTAMP:20260821T095127
CREATED:20180323T093917Z
LAST-MODIFIED:20180323T093917Z
UID:19817-1521763200-1524614399@ces.b2sg.org
SUMMARY:Human Genetics/WCI Open Rank Faculty Position - Tenure Path
DESCRIPTION:We seek exceptional individuals with dynamic and innovative cancer research programs with a specific focus in cancer genetics\, epigenetics\, and/or genomics. Successful candidates will be expected to maintain an independent federally funded research program and to participate in cancer center activities. This recruiting effort is part of a strategic initiative to create a cadre of first class scientists with closely related research interests in support of Winship’s Cancer Genetics and Epigenetics Research Program.\n\n\nAdditional Details\n\n\nInterested candidates should submit a Cover Letter indicating his/her research interest\, Curriculum vitae\, Statement of research accomplishments and goals (2 pages)\, and names of 3 potential references.-Successful candidates will hold an PhD\, MD or MD/PhD degree\, postdoctoral training\, and a strong track-record of peer-reviewed research publications and extramural funding.  \nThe Winship Cancer Institute of Emory University (Winship) in partnership with the Department of Human Genetics (DOHG) at Emory University School of Medicine invites applications from outstanding candidates for a tenure-path faculty position at the rank of Assistant\, Associate\, or Full Professor\, commensurate with experience. We seek exceptional individuals with dynamic and innovative cancer research programs with a specific focus in cancer genetics\, epigenetics\, and/or genomics. Successful candidates will be expected to maintain an independent federally funded research program and to participate in cancer center activities. This recruiting effort is part of a strategic initiative to create a cadre of first class scientists with closely related research interests in support of Winship¿s Cancer Genetics and Epigenetics Research Program.-76239BR
URL:https://ces.b2sg.org/event/emory-23mar18/
LOCATION:Emory University\, 201 Dowman Dr\, Atlanta\, GA\, 30322\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180324
DTEND;VALUE=DATE:20180426
DTSTAMP:20260821T095127
CREATED:20180324T111104Z
LAST-MODIFIED:20180324T111104Z
UID:19821-1521849600-1524700799@ces.b2sg.org
SUMMARY:Research Technician - Cancer Epigenetics
DESCRIPTION:Dr. Xiaobing Shi’s laboratory in the Center for Epigenetics at Van Andel Research Institute is seeking to hire one Research Technician. The Shi lab is among the leading groups in the study of regulation and recognition of histone modifications. The current research focus of the laboratory is to identify and characterize novel epigenetic readers and to determine their roles in human cancer with the long-term goal to translate the knowledge to the clinic. Main techniques used in the lab include molecular and cellular biology\, biochemistry and biophysics\, genetic and genomics\, mammalian cell culture and mouse model. \nThe Research Technician is expected to be responsible for the following tasks: \n\nmolecular cloning\nsmall-scale protein expression and purification\nbasic biochemical assays and detection of protein-protein interactions\nbasic cell culture and maintenance\ngeneral lab maintenance\nOther lab duties as requested\n\nRequirements: \nCandidates need to have a Bachelor’s or preferably a Master’s degree in biological sciences in the fields of biochemistry\, molecular and/or cell biology. A minimum 2 years of hands on bench experience is required. A successful candidate will be a self-disciplined\, highly organized team worker. \nApplication Process: \nQualified applicants should provide a cover letter\, a curriculum vitae\, and the names and address of three references to xiaobing.shi@vai.org\, and applying online. \nIf you possess these attributes and desire to help us drive science from the bench to the clinic; while benefiting from a highly generous compensation package; we would welcome speaking with you and encourage you to apply today. \nVAI is actively striving to diversify its workforce and strongly encourages qualified individuals from underrepresented groups to apply. Van Andel Institute is an EEO and Affirmative Action Employer. \nThis position will be open until filled. If you have any difficulty uploading your application or any questions\, please email Eric Miller at eric.miller@vai.org.
URL:https://ces.b2sg.org/event/van-24mar18/
LOCATION:Van Adel Research Institute\, Grand Rapids\, MI\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180325
DTEND;VALUE=DATE:20180427
DTSTAMP:20260821T095127
CREATED:20180325T093311Z
LAST-MODIFIED:20180325T093311Z
UID:19823-1521936000-1524787199@ces.b2sg.org
SUMMARY:Post Doctoral Associate
DESCRIPTION:A postdoctoral position is available in the laboratory of Dr. Merav Socolovsky in the Department of Cancer Biology at the University of Massachusetts Medical School. We investigate the process of mammalian blood cell differentiation\, with a focus on epigenetics and the cell cycle. Please visit the Socolovsky Lab Website ( http://labs.umassmed.edu/socolovskylab/) for details on available research areas. \n\n\n\nQualifications\n\n\n\nApplicants should have a Ph.D. in Cell\, Developmental or Molecular Biology\, be creative and highly motivated. \n\n\n\nAdditional Information\n\n\n\n\n\nPlease send a brief statement of your scientific work and interests\, a CV and the name and email address of three references\, to Merav.socolovsky@umassmed.edu  
URL:https://ces.b2sg.org/event/umass-25mar18/
LOCATION:UMass Medical School\,  55 N Lake Ave\, Worcester\, MA\, 01655\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180326
DTEND;VALUE=DATE:20180428
DTSTAMP:20260821T095127
CREATED:20180326T092407Z
LAST-MODIFIED:20180326T092747Z
UID:19826-1522022400-1524873599@ces.b2sg.org
SUMMARY:Scientist – Translational Sciences
DESCRIPTION:Constellation Pharmaceuticals is a premier epigenetics company\, focused on the discovery and development of novel\, small molecules targeting chromatin regulatory proteins in tumor and immune cells for therapeutic applications in oncology. Our unique discovery platform integrates our understanding of chromatin-regulatory mechanisms with cancer and immune pathways to optimize our drug discovery activities and fully enable the clinical translation of our programs. \nThe Department of Translational Sciences at Constellation seeks a motivated Scientist to conduct research to support the advancement of portfolio small molecule inhibitors into clinical trials in targeted cancer indications and patient populations. The incumbent will identify predictive biomarkers for enrichment of patient populations most likely to respond to our agents in the clinic\, and pharmacodynamic biomarkers to monitor target engagement. The position requires expertise in cancer biology and/or chromatin biology\, and a passion to contribute to high quality scientific research to drive programs into the clinic. We are seeking a highly motivated\, independent\, and skilled candidate who will be responsible for planning\, execution\, interpretation and presentation of data to drive translational programs. \nThe primary responsibilities will include: \n\nKey contributor to translational science programs\, and delivery of scientific discoveries impacting decision-making at team meetings\nDesign and perform complex chromatin-focused experiments to support hypotheses around the biological functions and molecular mechanisms of oncology targets\nIdentification/validation of biological contexts that create a dependency on a given drug target to aid indication/context prioritization for clinical development. This entails both performing and guiding internal efforts\, as well as external efforts with CROs or collaborators.\nClosely work with bioinformatics group to use genomic\, epigenomic\, and/or transcriptomic data to generate novel biomarker hypotheses and identify novel biomarkers\nIdentification and clinical translation of biomarker assays that assess drug pharmacodynamics\, and allow testing of preclinical response hypotheses enabling differentiating path for small molecular inhibitor development\nBe part of a highly skilled translational team that shares a common goal of delivering optimal path forward for clinical development.\n\nRequirements: \n\nPh.D. in molecular or cellular biological sciences with emphasis on chromatin and/or cancer biology\, and 3-5 years of work experience (post-doctoral\, industry position or equivalent)\nBroad knowledge and laboratory research experience in oncology and/or epigenetics space as demonstrated by peer-reviewed publications\nFlexibility to work across diverse areas\, utilization of next-generation sequencing technologies and familiarity with using pathway analysis and bioinformatics data analysis software\nDetail-oriented\, self-motivated\, and ability to work independently\nStrong oral and written communication skills\, writing reports and giving updates at team meetings is required. The ability and desire to work in a challenging dynamic environment under tight deadlines is required
URL:https://ces.b2sg.org/event/const-26mar18/
LOCATION:Constellation Pharmaceuticals\, 215 First Street\, Cambridge\, MA\, 02142\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180328
DTEND;VALUE=DATE:20180430
DTSTAMP:20260821T095127
CREATED:20180328T103020Z
LAST-MODIFIED:20180328T103020Z
UID:19829-1522195200-1525046399@ces.b2sg.org
SUMMARY:Postdoctoral Fellow
DESCRIPTION:We are seeking one motivated postdoctoral fellow or research associate to study  \n1) The biology of Chimeric Antigen Receptor T ( CAR -T) and NK ( CAR -NK) cells and characterize these CAR -T and CAR -NK cells (Mol Ther. 2018\, PMID : 29503199) for development of innovative therapies for chronic viral infection and virus-related malignancies with the ultimate goal of administering them to patients as part of a future clinical trial.  \n2) The cell biology of NK cell\, with a focus on NK cell inhibitory receptor signaling (Immunity. 2012\, PMID : 22464172) and immunological synapse (Immunity\, 2009\, PMID : 19592272) using human NK cells and novel NK-specific knockout mice.  \nWe are using molecular\, biochemical\, immunological\, and imaging strategies\, as well as biophysical approaches for understanding human lymphocyte dysfunction in chronic infectious diseases and cancer.  \nAll applicants with experience in molecular & cell biology\, molecular cloning\, immunology\, or imaging are encouraged to apply.  \nThis post-doctoral fellowship will provide the opportunity to apply cutting-edge techniques to study the biology of cytotoxic lymphocytes and CAR -T and CAR -NK cells in the laboratory of Dongfang Liu.  \nHouston Methodist\, a teaching hospital affiliated with Weill Cornell Medical College\, Cornell University\, is located at the vibrant Texas Medical Center in Houston\, TX.  \nSalary will be commensurate with NIH post-doctoral pay scales.  \nPlease attach with your application\, a cover letter\, CV\, and contact information for 3 references to Dongfang Liu ( dliu2@houstonmethodist.org )
URL:https://ces.b2sg.org/event/hmri-28mar18/
LOCATION:Houston Methodist Research Institute\, 6670 Bertner Ave\, Houston\, TX\, 77030\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180330
DTEND;VALUE=DATE:20180501
DTSTAMP:20260821T095127
CREATED:20180330T161613Z
LAST-MODIFIED:20180330T161613Z
UID:19831-1522368000-1525132799@ces.b2sg.org
SUMMARY:Bioinformatics Research Scientist
DESCRIPTION:St. Jude Children’s Research Hospital’s Department of Tumor Cell Biology is looking for a highly motivated bioinformatics research scientist as the key analyst for the genomics and epigenomics projects of the Department of Tumor Cell Biology\, in close collaboration with the Department of Computational Biology. The goal of the Tumor Cell Biology department\, led by Dr. Charles J. Sherr\, an HHMI investigator\, is to understand how oncogenes\, tumor suppressors and checkpoint monitors of cellular stress govern tumor initiation\, progression\, and responses to cancer therapy.  Emphasis is placed on developing preclinical models of pediatric cancers\, including medulloblastoma and acute lymphoblastic leukemia to run pre-clinical trials to improve current therapies. Members of the Department of Tumor Cell Biology publish in high profile journals in Cancer Biology\, including Nature\, Cancer Cell\, Cancer Research and E-Life. The Computational Biology Department has a well-established track record in leading bioinformatics analysis for high-profile genomic and translational research projects such as the St. Jude/Washington University Pediatric Cancer Genome Project. Specific projects include the integrative analysis of ChIP-seq of histone marks and transcription factors\, ATAC-seq\, Hi-C\, Capture-seq\, whole-genome and whole exome sequencing\, whole transcriptome RNA-seq data to understand the mechanism of key molecular pathways involved in tumorigenesis especially medulloblastoma. Candidates with understanding of cancer genomics\, epigenomics and/or genetics\, strong problem solving skills\, attention to detail\, critical thinking\, and expertise in next-generation sequencing data analysis are highly encouraged to apply for this position. \nMinimum Experience\n\n\n\n\nPh.D which must include research related to bioinformatics (such as analysis of sequence data\, microarrays\, SNPs\, image data\, proteomics data\, or biological pathways; development of algorithms\, statistical methods\, or scientific software); OR If Ph.D with no bioinformatics research\, then two (2) years of pre-or postdoctoral experience in Computational Biology or Bioinformatics research is required\nExperience with programming languages such as Perl\, C\, or Java required\n\nPreferred skills:   \n\nExperience with Python and knowledge on statistical analysis package such as R and Matlab is highly desired. Experience in epigenetics analysis such as ChIP-seq\, ATAC-seq\, DNase I hypersensitivity-seq\, 4C-seq\, ChIA-PET\, WGS is preferred. Knowledge about neurobiology is also a plus.\n \n\n\n\n\nMinimum Education\n\n\n\n\nPh.D. in Molecular Biology\, Biochemistry\, Computer Science\, Statistics\, Mathematics\, Bioinformatics or related field required.\nPh.D. which must include research related to bioinformatics (such as analysis of sequence data\, microarrays\, SNPs\, image data\, proteomics data\, or biological pathways; development of algorithms\, statistical methods\, or scientific software). \nOR\nIf Ph.D. with no bioinformatics research\, then two (2) years of pre-or postdoctoral experience in Computational Biology or Bioinformatics research is required
URL:https://ces.b2sg.org/event/stjude-30mar18/
LOCATION:St. Jude Children’s Hospital\, 262 Danny Thomas Pl\, Memphis\, TN\, 38105\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180405
DTEND;VALUE=DATE:20180507
DTSTAMP:20260821T095127
CREATED:20180405T063526Z
LAST-MODIFIED:20180405T063712Z
UID:19833-1522886400-1525651199@ces.b2sg.org
SUMMARY:Postdoctoral Fellow - Cancer Genetics\, Epigenetics
DESCRIPTION:NCI-funded positions are available now for motivated\, creative post-doctoral candidates interested in fundamental molecular mechanisms ensuring genomic and epigenomic stability and how the mechanistic deficiency relate to cancer initiation\, progression\, and therapeutic intervention. For more scientific background\, please refer to our recent publications (Nature Medicine 13:812-819\, 2007; Nature Chem. Biol. 6:766-773\, 2010; Mol. Cell. 47:444-456\, 2012; EMBO J. 32:1425-1439\, 2013).  \nMinimum Education and Skills Required for Consideration:\nBoth new Ph.D. graduates and more established Ph.D.s with a solid background in molecular and cell biology or related fields are welcome to apply.  \nExcellent communication skills with the ability to work independently and as part of a team are a plus.  \nApplicants interested in innovative and integrative basic research with great interest and expertise in cancer genetics and epigenetics are strongly encouraged to apply. 
URL:https://ces.b2sg.org/event/hope-5apr18/
LOCATION:City of Hope\, 1500 East Duarte Road\, Duarte\, 91010\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180405
DTEND;VALUE=DATE:20180507
DTSTAMP:20260821T095127
CREATED:20180405T064846Z
LAST-MODIFIED:20180405T065022Z
UID:19837-1522886400-1525651199@ces.b2sg.org
SUMMARY:Associate Investigator
DESCRIPTION:The Associate Investigator is a self-sustaining Scientist and has achieved recognition in his/her field. The Associate Investigator heads a Laboratory and is responsible for the hiring\, training and management of his/her Lab personnel and for assuring that they work according to the Baylor Scott & White Research Institute (BSWRI) standards. While the Associate Investigator may receive supplemental funds from BSWRI\, it is the Investigator’s responsibility to obtain grants that will support his/her research and to produce data that is worthy of publication in leading journals and has patent potential. The Associate Investigator is part of the BSWRI faculty and plays a role in the continued growth and development of BSWRI. He/she may be asked to serve on committees\, develop collaborations or act as a liaison with external departments.  \nThe ideal candidate for the Associate Investigator role will be a PhD Scientist with a proven track record of leading a research team\, securing their own grants\, and consistently being published in their field. \n\nDoctorate Degree required\n4 years of experience required
URL:https://ces.b2sg.org/event/bsw-5apr18/
LOCATION:Baylor Scott & White Health (BSWH)\,  3500 Gaston Ave\, Dallas\, TX\, 75246-2017\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180406
DTEND;VALUE=DATE:20180508
DTSTAMP:20260821T095127
CREATED:20180406T074448Z
LAST-MODIFIED:20180406T074950Z
UID:19840-1522972800-1525737599@ces.b2sg.org
SUMMARY:Postdoctoral Fellow
DESCRIPTION:A Postdoctoral Fellow position is available in Dr. Chuong Dinh Hoang’s laboratory within the Thoracic and Gastrointestinal Oncology Branch (TGIB) \, National Cancer Institute\, NIH.  \nOur broad goal is to explore the molecular and cellular biology of thoracic cancers\, namely mesothelioma and/ or non-small cell lung carcinoma\, thymoma\, etc. Currently\, we have projects that involve investigating microRNA-mRNA interactions in malignant mesothelioma. New projects will focus on the pathogenic signaling pathways relevant to tumor initiation\, invasion\, metastasis\, and resistance. With these projects\, we have translational aims of developing novel molecular biomarkers and therapeutic targets based on an understanding of the pathogenetic mechanisms active in these cancers. Also\, we are developing novel delivery platforms for nucleic-based agents that require pre-clinical testing in mouse tumor models. The culmination of these projects will be linked to clinical human protocols in these thoracic cancers of interest.  \nThis is a great opportunity for candidates who are interested in cancer biology and want to enhance their career potential by working in our research program with outstanding support of other established laboratories and core facilities in the National Cancer Institute. This laboratory effort will be in close collaboration with other faculty in our branch. We work closely with the Thoracic Oncology Section of David S. Schrump\, M.D. (Chief\, TGIB)\, which focuses on epigenetic mechanisms and regulation of thoracic tumors; and with the lab of Dr. Taylor Ripley\, M.D. \, which focuses on metabolism of thoracic tumors.  \nExperience Required: \nQualified candidates should have a Ph.D. in a biological science area or the equivalent background (M.D.\, M.B.B.S.\, etc.) with one to five years of postdoctoral experience. A background and working knowledge in molecular and cellular biology is required. Familiarity with basic techniques including DNA/ RNA isolation\, cell culture techniques Western-blot\, quantitative PCR\, immunohistochemistry\, ChIP\, retroviral or lentiviral transfections\, FACS sorting\, and working with mice are a must. Knowledge and/or experience in bioinformatics\, biostatistics\, mutation detection\, microarray analysis\, RNA-seq and other sequencing methodology\, and microRNA is preferred. Previous research experience in cancer or stem cell biology is advantageous\, but not required.
URL:https://ces.b2sg.org/event/nih-6apr18/
LOCATION:National Institutes of Health (NIH) campus\, Bethesda\, MD\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180406
DTEND;VALUE=DATE:20180508
DTSTAMP:20260821T095127
CREATED:20180406T085910Z
LAST-MODIFIED:20180406T085910Z
UID:19844-1522972800-1525737599@ces.b2sg.org
SUMMARY:Post-Doctoral Research Fellow
DESCRIPTION:The Program in Prostate Cancer Research and the Division of Human Biology seeks a Postdoctoral Fellow to perform studies exploring the molecular mechanisms underlying metastatic prostate cancer.\nThe particular areas of emphasis for this position center on studies of cancer genomics\, epigenetics\, cell-free DNA\, prostate cancer biomarkers\, and treatment strategies. We are recruiting a post-doctoral fellow to engage in laboratory-based studies of these processes. This is a basic science position that focuses on delineating the molecular mechanisms of metastatic prostate cancer with the opportunity for translational studies evaluating the efficacy and outcome of novel therapeutics.\n\n\n\nQualifications\n\n\n\nPh.D. degree in biology; biochemistry; genetics; molecular biology; cell biology; immunology or related field is required. Additionally\, experience in one of the following areas is required: genomics/genetics\, analysis of inflammation/immune composition\, biomarker characterization. Knowledge/exposure in biobanking\, clinical trial design\, and biostatistics is desired\, as well as a demonstrated track record of high-quality publications. Expertise/skills in molecular biology techniques is required: RT-PCR\, immunohistochemistry\, ELISA\, cell culture\, drug toxicity assays. Candidates need to be highly-motivated\, organized individuals who think independently but enjoy working as part of a dynamic\, collaborative\, and multidisciplinary team. Excellent verbal and written communication skills are essential.
URL:https://ces.b2sg.org/event/fh-6apr18/
LOCATION:Fred Hutchinson Cancer Research Center
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180406
DTEND;VALUE=DATE:20180508
DTSTAMP:20260821T095127
CREATED:20180406T091115Z
LAST-MODIFIED:20180406T105243Z
UID:19846-1522972800-1525737599@ces.b2sg.org
SUMMARY:Faculty Position in Biochemistry
DESCRIPTION:The Biochemistry and Molecular Genetics Department at Northwestern University Feinberg School of Medicine seeks a full-time tenure track Investigator at the rank of Assistant\, Associate or full Professor. \nNorthwestern University Feinberg School of Medicine has committed substantial resources toward expanding interdisciplinary research in the Biochemistry and Molecular Genetics Department. A new Department of Biochemistry and Molecular Genetics\, with founding faculty members from the Department of Molecular Pharmacology and Biological Chemistry\, is led by Dr. Ali Shilatifard\, an internationally recognized leader in chromatin biology\, gene expression and epigenetics\, and on how the misregulation of these pathways contributes to human cancer. We are now seeking candidates to fill a new full-time\, tenure track faculty position at the Assistant\, Associate\, or full Professor rank. Northwestern University offers a collegial and collaborative scientific environment that is rich with core facilities\, robust cross-disciplinary graduate training programs\, and diverse expertise. \nCandidates should have a PhD\, MD/PhD or MD degree\, significant research experience\, and evidence of sustainable extramural funding. Salary is commensurate with experience. The start date is negotiable and applications will be accepted until the position is filled. \nPlease read ALL instructions and make preparations before proceeding to the application page: \n\nApplications will only be accepted via online submission (see link below).\nPlease prepare all documents in advance as Adobe PDF files\, and please be sure all information is entered correctly and accurately (especially names and email addresses)\, as there will be no opportunity for online revision after your application has been submitted.\nAll required fields in the application form are marked with an asterisk and must be filled before clicking the “Submit” button.\nBe aware that incomplete applications cannot be saved.
URL:https://ces.b2sg.org/event/nwu-6apr18/
LOCATION:Northwestern University\, 633 Clark St\, Evanston\, IL\, 60208\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180407
DTEND;VALUE=DATE:20180509
DTSTAMP:20260821T095127
CREATED:20180407T084021Z
LAST-MODIFIED:20180407T084056Z
UID:19851-1523059200-1525823999@ces.b2sg.org
SUMMARY:Post Doctoral Associate
DESCRIPTION:Postdoctoral Position in Epigenetics\, the Cell Cycle and Hematopoiesis at the University of Massachusetts Medical School\n\n\n\nResponsibilities\n\n\n\nA postdoctoral position is available in the laboratory of Dr. Merav Socolovsky in the Department of Cancer Biology at the University of Massachusetts Medical School. We investigate the process of mammalian blood cell differentiation\, with a focus on epigenetics and the cell cycle. Please visit the Socolovsky Lab Website ( http://labs.umassmed.edu/socolovskylab/) for details on available research areas.\n\n\n\nQualifications\n\n\n\nApplicants should have a Ph.D. in Cell\, Developmental or Molecular Biology\, be creative and highly motivated.\n\n\n\nAdditional Information\n\n\n\n\n\nPlease send a brief statement of your scientific work and interests\, a CV and the name and email address of three references\, to Merav.socolovsky@umassmed.edu\n\n\n\n\n\n(Please do not apply via the UMMS Career Site)
URL:https://ces.b2sg.org/event/umms-7apr18/
LOCATION:UMass Medical School\,  55 N Lake Ave\, Worcester\, MA\, 01655\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180407
DTEND;VALUE=DATE:20180509
DTSTAMP:20260821T095127
CREATED:20180407T084819Z
LAST-MODIFIED:20180407T084819Z
UID:19853-1523059200-1525823999@ces.b2sg.org
SUMMARY:Research Fellow
DESCRIPTION:Two fully funded post-doctoral positions are available in the lab of Dr. Carl Novina in the Cancer Immunology and Virology Program at Dana-Farber Cancer Institute (http://novinalab.dana-farber.org/). The positions are available for the translation of (1) autologous T cell therapies for solid tumors including chimeric antigen receptors (CAR-T cells) and (2) targeted epigenetic reprogramming of immune cells.\nSuccessful candidates will work in a collaborative and entrepreneurial team of researchers and clinicians to develop and evaluate the efficacy of novel cell and molecular therapies.\nInterested individuals should submit a cover letter and curriculum vitae and contact information for three references.\n\n\n\nQualifications\n\n\n\nCandidates should have a PhD or MD/PhD in immunology or a related field and at least one first author peer-reviewed publications\, with significant experience in standard immunological assays. Expertise in neuroimmunology\, immunotherapy\, and/or human immunobiolgy preferred.
URL:https://ces.b2sg.org/event/df-7apr18/
LOCATION:Dana-Farber Cancer Institute\, 450 Brookline Avenue\, Boston\, MA\, 02215\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180410
DTEND;VALUE=DATE:20180512
DTSTAMP:20260821T095127
CREATED:20180410T153027Z
LAST-MODIFIED:20180506T084356Z
UID:19855-1523318400-1526083199@ces.b2sg.org
SUMMARY:Postdoctoral Fellow - Skeletal Disease
DESCRIPTION:We are looking for a motivated and collaborative postdoctoral fellow to join the lab of Dr. Tao Yang at Van Andel Research Institute in Grand Rapids\, MI. \nThe Yang Laboratory is interested in the mechanisms regulating skeletal physiology and disease development\, with an emphasis on skeletal stem cell/progenitors differentiation and pool maintenance. A combined approach using in vivo and in vitro models allows the lab to study the molecular mechanisms underlying osteoarthritis\, osteoporosis\, and bone tumors. \nThis postdoctoral position is available IMMEDIATELY and is for a motivated scientist who meets the qualifications and description outlined below. This fellow will investigate the novel mechanisms of sumoylation pathways in mesenchymal stem cell stemness\, differentiation\, and maintenance during skeletal aging and diseases. A few intriguing phenotypes of these genetic mouse models have been established in our genetic mouse models awaiting mechanistic and translational studies. \nQualifications: \n\nA Ph.D. or M.D./Ph.D. in molecular and cell biology\, developmental biology\, and/or biochemistry.\nExperience with genetic mouse models\, stem cell biology\, skeletal biology\, epigenetics\, and/or cancer biology is preferred.\nA strong record of peer-reviewed publication is highly desirable.\n\nInterested applicants should apply online AND send a cover letter describing research experience and interests\, a CV\, and contact information of three references to tao.yang@vai.org. \nIf you have any difficulty uploading your application or any questions\, please email Eric Miller at eric.miller@vai.org.
URL:https://ces.b2sg.org/event/vari-10apr18/
LOCATION:Van Adel Research Institute\, Grand Rapids\, MI\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180410
DTEND;VALUE=DATE:20180513
DTSTAMP:20260821T095127
CREATED:20180410T161133Z
LAST-MODIFIED:20180508T101237Z
UID:19857-1523318400-1526169599@ces.b2sg.org
SUMMARY:Research Fellow
DESCRIPTION:A Research Fellow position is available in the program of Dr. Keith Robertson. For more information about Dr. Robertson’s program\, please see: http://www.mayo.edu/research/faculty/robertson-keith-d-ph-d/bio-20035097 \nThe successful candidate will join the Epigenetic Etiology of Human Disease Laboratory to study the role of DNA epigenetic modifications in human disease. More specifically\, he/she will examine how DNA methylating and hydroxymethylating enzymes regulate their respective DNA epigenetic modifications and how these marks modulate expression and genome stability\, and interface with other epigenetic modifications. Disease focus areas of the laboratory include cancer (hepatocellular and renal)\, obesity\, and diabetes. Specific research areas include application of genome-wide epigenomics methods to decipher DNA methylation/hydroxymethylation defects in cancer and biochemical/cell culture-based techniques to study the regulation and interactions between chromatin remodeling factors (e.g. DNMTs\, TETs\, HMTases) and the roles of their target loci in driving disease. Techniques commonly used in the laboratory include: quantitative RT-PCR\, western blotting\, cell culture\, transfections\, bisulfite sequencing\, DNA immunoprecipitation\, pyrosequencing\, ChIP-qPCR\, ChIP-seq\, next-gen library preparation and sequencing\, Infinium 850k arrays\, bioinformatics analysis\, microscopy\, and biochemical analysis of protein function. Experience in one or more of these areas is a plus. The candidate will play a major role in the preparation of manuscripts that arise from this work and devote 100% effort to these tasks (no patient contact or other responsibilities). \nPosition description \nA Research Fellow at Mayo Clinic is a temporary position intended to provide training and education in research. Individuals will train in the research program of a Mayo Clinic principal investigator. Qualified individuals will demonstrate the potential for research as evidenced by their training and peer-reviewed publications and should become competitive for national research grants. Proof of English proficiency is required for J-1 Short-Term Scholars\, Research Scholars\, Professors\, Specialists\, and Student Interns sponsored by Mayo Clinic. 800146; J2WRTP \nQualifications \nMust have a Ph.D.\, M.D.\, or equivalent doctoral degree in a field deemed relevant by the program. Research Fellow is appropriate for individuals who have completed no more than one prior postdoctoral fellowship\, at Mayo Clinic or elsewhere. Please attach the following required documents at the time of application: \n\nCurrent curriculum vitae and bibliography\nThree letters of recommendation\, signed\, on letterhead\, describing:\n\nRelationship to the applicant.\nPast work/academic performance.\nWork qualities/personal conduct.\nOverall assessment of potential for success in research environment.\n\n\nDoctoral degree certification\, if applicable:\n\nOriginal or notarized copy of diploma or final transcript issued by school (English translation required).
URL:https://ces.b2sg.org/event/mayo-10apr18/
LOCATION:Mayo Clinic\, 200 1st St SW\, Rochester\, MN\, 55905\, United States
CATEGORIES:Jobs
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DTSTART;VALUE=DATE:20180410
DTEND;VALUE=DATE:20180513
DTSTAMP:20260821T095127
CREATED:20180410T163514Z
LAST-MODIFIED:20180508T102102Z
UID:19860-1523318400-1526169599@ces.b2sg.org
SUMMARY:Senior Scientist/Principal Scientist - Computational Biology
DESCRIPTION:he Senior Scientist /Principal Scientist leads the identification and incorporation of new technologies or best practices to enhance a specific scientific or technical area and/or leads a portfolio project. She/he also identifies and proposes external collaborations.\n\nIn the Bioinformatics Expert role\, the incumbent works as a member of Cross-Functional Project Teams and contributes to the discovery of First-in-Class or Breakthrough drugs. Evaluate\, acquire/develop\, and champion the use of genomics data and bioinformatics tools as a foundation to drive innovation in the BI portfolio. Support new therapeutic concept (NTC) discovery\, proof of clinical principal (PoCP)\, and mechanism of action (MOA) studies. Lead/contribute to disease and mechanistic model characterization to expand the role of genes\, pathways\, and cell types in the pathogenesis\nAs an employee of Boehringer Ingelheim\, you will actively contribute to the discovery\, development and delivery of our products to our patients and customers. Our global presence provides opportunity for all employees to collaborate internationally\, offering visibility and opportunity to directly contribute to the companies’ success. We realize that our strength and competitive advantage lie with our people. We support our employees in a number of ways to foster a healthy working environment\, meaningful work\, diversity and inclusion\, mobility\, networking and work-life balance. Our competitive compensation and benefit programs reflect Boehringer Ingelheim’s high regard for our employees\nDuties & Responsibilities:\n\nDevelopment of Analysis Plans in close collaboration with the TA Partner\, by 1)providing conceptual input into analysis plans (approaches and experimental design)\, and 2)engaging in cross-functional discussions to refine plans and identify key priorities\nCompletes bioinformatics data analysis as specified by analysis plans\, and provides interpretation and context to results of analysis\nIdentify\, evaluate\, and apply new methodologies and emerging technologies\, and develop software tools when appropriate\, to contribute to projects across TAs\nDemonstrate a high level of AAI capabilities by taking the initiative without waiting for direction\, working with a sense of urgency to discover breakthrough medicines that will improve patients’ lives\, sharing ideas beyond own team\, and challenging the status quo\n\nSenior Scientist Requirements:\n\nPh.D. degree or equivalent from an accredited institution in biological\, statistical\, computational\, or other quantitative science.\nTwo (2) or more years of relevant experience in drug discovery or biomedical research environment after completing a doctoral degree.\nIs a locally recognized science and/or technology subject matter expert within his/her department who develops and implements experimental approaches that contribute to department/Discovery Research goals by demonstrating expert knowledge to advance the portfolio. The development of a strong publication record within his/her expertise area is expected.\nExperience with experiment design\, and hands-on NGS (RNAseq\, single-cell NGS\, whole genome\, exome\, miRNA\, or mcrobiome) data processing and analysis.\nExperience in biological pathways\, data visualization\, network and systems biology (GSEA\, GeneGO\, CBDD\, Cytoscape\, Reactome).\nProficiency using R and Bioconductor packages and one or more programming language (Python\, Perl\, and Javascript).\nTrack record of designing\, leading\, and managing computational research projects.\nBackground in or familiarity with gene expression data (microarray\, RNA seq) analysis and biological interpretation.\nUnderstanding of biology of the diseases relevant to at least one of the TAs in Ridgefield (I&R\, CMDR\, and Cancer Immunology).\nExcellent communication and presentation skills.\nExperience working with patient-centric data\, GWAS\, and eQTL analysis is desirable.\nExperience working with Linux environment\, high performance computing clusters\, and cloud computing.\nIs a recognized expert in an area of genomics\, proteomics\, epigenetics\, and/or other high dimensional data analysis; always up-to-date with the latest methods developments in the field; fully understands internal capabilities in the area\, as well as external capabilities (service providers as well as academics and collaborators)\nProvides expert-level scientific and bioinformatics expertise within the area(s) of biology and human disease addressed by the TAs. Knowledge of current key datasets\, therapeutic landscape and demographic/epidemiological considerations within TA is required.\nComply with all company policies\, and maintain high quality of data and analyses (consistency checks at the logical and scientific level are implemented)\n\n\nPrincipal Scientist Requirements: \n\nPh.D. degree or equivalent from an accredited institution in biological\, statistical\, computational\, or other quantitative science.\nFive (5) or more years of relevant experience in drug discovery or biomedical research environment after completing a doctoral degree\, with at least two (2) years’ experience in drug discovery.\nIs a recognized science and/or technology subject matter expert across BI with a sustained publication and external presentation record.\nShe/he identifies new methodologies\, protocols and/or test procedures that contribute to department and Discovery Research goals and proactively proposes creative solutions to department or Discovery Research leadership.\nExperience with experiment design\, and hands-on NGS (RNAseq\, single-cell NGS\, whole genome\, exome\, miRNA\, or mcrobiome) data processing and analysis.\nExperience in biological pathways\, data visualization\, network and systems biology (GSEA\, GeneGO\, CBDD\, Cytoscape\, Reactome).\nProficiency using R and Bioconductor packages and one or more programming language (Python\, Perl\, and Javascript).\nTrack record of designing\, leading\, and managing computational research projects.\nBackground in or familiarity with gene expression data (microarray\, RNA seq) analysis and biological interpretation.\nUnderstanding of biology of the diseases relevant to at least one of the TAs in Ridgefield (I&R\, CMDR\, and Cancer Immunology).\nExcellent communication and presentation skills.\nExperience working with patient-centric data\, GWAS\, and eQTL analysis is desirable.\nExperience working with Linux environment\, high performance computing clusters\, and cloud computing.\nIs a recognized expert in an area of genomics\, proteomics\, epigenetics\, and/or other high dimensional data analysis; always up-to-date with the latest methods developments in the field; fully understands internal capabilities in the area\, as well as external capabilities (service providers as well as academics and collaborators)\nProvides expert-level scientific and bioinformatics expertise within the area(s) of biology and human disease addressed by the TAs.\nKnowledge of current key datasets\, therapeutic landscape and demographic/epidemiological considerations within TA is required.\nComply with all company policies\, and maintain high quality of data and analyses (consistency checks at the logical and scientific level are implemented)\n\n\nEligibility Requirements:\n\nMust be legally authorized to work in the United States without restriction.\nMust be willing to take a drug test and post-offer physical (if required)\nMust be 18 years of age or older
URL:https://ces.b2sg.org/event/boehringer-10apr18/
LOCATION:Boehringer Ingelheim\, Ridgefield\, CT\, United States
CATEGORIES:Jobs
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DTSTART;VALUE=DATE:20180412
DTEND;VALUE=DATE:20180515
DTSTAMP:20260821T095127
CREATED:20180412T155933Z
LAST-MODIFIED:20180412T155933Z
UID:19865-1523491200-1526342399@ces.b2sg.org
SUMMARY:Senior Scientific Researcher
DESCRIPTION:We are seeking a Senior Scientific Researcher in the Department of Molecular Biology to support the production and optimization of genetically-modified cellular models. This position will be within the newly-established Cell Engineering Lab\, wherein she/he will facilitate the design\, execution\, and validation of cell line engineering projects initiated by researchers across Genentech – with the ultimate goal of generating more effective in vitro/ex vivo disease models and novel contexts for functional genomic screening. The candidate is expected to work creatively and independently within an extremely dynamic\, collaborative research environment. \nWho You Are\nA self-motivated candidate with a PhD in Genetics\, Molecular Biology\, Biochemistry\, Cancer Biology\, or a related discipline. Qualified candidates will have a skillset demonstrating successful\, documented application of molecular genetics/genome engineering either in cell-based systems or model organisms. Preferred expertise includes some or all of the following: DNA nucleases\, 2D and 3D cell culture\, RNA interference (siRNA/shRNA)\, reporter gene assays\, primary and/or stem cell models\, molecular cloning\, RNA/DNA/protein quantification\, epigenetics\, and viral vector development/use. Working knowledge of pooled vector-based screening\, Next-Gen Sequencing (NGS)\, biostatistics\, and/or basic bioinformatics is desirable. The successful candidate will be team-oriented\, highly organized\, and have excellent communication skills\, both written and verbal. \n\nLI-gRED-JM1
URL:https://ces.b2sg.org/event/genentech-12apr18/
LOCATION:Genentech\, 1 DNA Way\, South San Francisco\, CA\, 94080\, United States
CATEGORIES:Jobs
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