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X-WR-CALNAME:Cancer Epigenetics Society
X-ORIGINAL-URL:https://ces.b2sg.org
X-WR-CALDESC:Events for Cancer Epigenetics Society
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TZID:Europe/Paris
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DTSTART:20180325T010000
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DTSTART:20181028T010000
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DTSTART;VALUE=DATE:20180322
DTEND;VALUE=DATE:20180424
DTSTAMP:20260821T163919
CREATED:20180322T093847Z
LAST-MODIFIED:20180322T094520Z
UID:19810-1521676800-1524527999@ces.b2sg.org
SUMMARY:Quantitative Image Analyst - Immuno-oncology
DESCRIPTION:We seek a highly motivated quantitative Image Analyst to be part of a larger inter-disciplinary team that focuses on target discovery\, validation and biomarker research in immune-oncology. The successful candidate should have deep knowledge of image analysis methods and know how to apply them towards a better understanding of tumor immune microenvironment in response to various immunotherapies. The image analyst will work closely with immunologists\, biologists\, computational biologists and translational oncologists\, to support a diverse set of research programs and should enjoy operating in a highly dynamic and cooperative environment. The candidate should have the ability to work independently and come up with quick\, robust and creative computational tissue image analysis solutions to various research goals. \nRole Responsibilities \n\nUtilize and develop cutting edge image analysis techniques that accurately QC\, segment\, register\, and quantify digital histopathology images\, to understand spatial changes in the tumor immune microenvironment and ultimately predict biomarkers in response to various cancer immunotherapies.\nPerform morphological immunophenotyping of tumors using deep understanding of statistical and predictive modeling concepts\, machine-learning approaches including but not limited to deep learning\, clustering and classification techniques\, and image segmentation strategies\nQuantify and interpret highly multiplex immunofluorescent images on tissue samples from preclinical models and human subjects\, to define the phenotype\, functionality\, and localization of immune and other cells within complex tissue types in both 2D and 3D settings.\nDevelop innovative algorithmic and statistical approaches to integrate diverse datasets (IHC/IF images\, FACS/cyTOF\, RNA-seq\, DNA-seq\, epigenetics) from preclinical models and clinical trials to identify targets\, biomarkers\, resistance mechanisms of current therapies\, and predict effective therapeutic combinations\nBe up-to-date on state-of-the-art methods and techniques in computational image analysis and provide support on an as-needed basis to cross-disciplinary project teams\n\nQualifications \nEducation and Experience \n\nPhD in Bioinformatics/Computational Biology\, Immunology\, Mathematics\, Statistics\, Biostatistics or closely related field with 8+ years of post-PhD experience with substantial expertise in using advanced computational image analysis platforms for image processing\, analysis\, and visualization across various tissue architectures\nProven record of scientific rigor and scientific success\nAbility to work effectively on teams and good team player attitude required\nExcellent communication skills (oral and written) as demonstrated by publications & presentations\nAbility to multi-task and project prioritization required\n\nTechnical Skill Requirements \n\nExperience in applying and developing state-of the-art image analysis techniques and methods on images from latest immunohistochemistry techniques (multiplex IF/IHC\, ISH) across various tissue architectures.\nAbility to categorize and analyze data sets via neural networks and associated deep learning technologies (including but not limited to TensorFlow library) facilitating quantitative processing and interpretation of highly multiplex immunofluorescent images\nAbility to identify and discern patterns and insights within structured and unstructured data.\nAbility to work closely with bench scientists to troubleshoot and solve potential imaging artifacts\nExcellent programming experience in machine learning and deep learning (C++\, Python/Perl\, R\, Matlab)\nAuthorship demonstrating the application of image analysis in high quality publications\n\nPreferred Qualifications \n\nDemonstrated understanding of biology (specifically immunology) desirable\nExperience in analysis of large-scale genomic data such as RNA-seq\, Exome-seq\, whole-genome seq\, ChIP-Seq\, genotype\, microarrays and flow/mass cytometry desirable\nProficiency in developing web-based applications and ability to code in Java desirable
URL:https://ces.b2sg.org/event/pfizer-22mar18/
LOCATION:Pfizer – Pearl River\, NY\, 401 North Middletown Road\, Pearl River\, NY\, 10965\, United States
CATEGORIES:Jobs
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180322
DTEND;VALUE=DATE:20180424
DTSTAMP:20260821T163919
CREATED:20180322T100626Z
LAST-MODIFIED:20180322T100626Z
UID:19812-1521676800-1524527999@ces.b2sg.org
SUMMARY:Staff Research Associate I/II
DESCRIPTION:JOB OVERVIEW\nUnder direct supervision and with training provided\, the Staff Research Associate II (SRA II) will provide research assistance for the Munster Laboratory in the Division of Hematology/Oncology\, Department of Medicine. The research program in the Munster laboratory focuses on the epigenetic modulation of therapy resistance\, with a focus on improving treatments for breast and other cancers.  \nDEPARTMENT OF MEDICINE\nThe Department of Medicine\, with annual revenues of $417 million\, is the largest department in the UCSF School of Medicine. The mission of the Department is research (basic and clinical)\, teaching\, patient care\, and public service.  \nABOUT UCSF \nThe University of California\, San Francisco (UCSF) is a leading university dedicated to promoting health worldwide through advanced biomedical research\, graduate-level education in the life sciences and health professions\, and excellence in patient care. It is the only campus in the 10-campus UC system dedicated exclusively to the health sciences. \n\n\nRequired Qualifications \n• BA/BS degree in a immunology or related science and one or more years of recent\, directly related work experience following degree completion\, utilizing the techniques or methods required by the position; or an equivalent combination of education and experience\n• Experienced in processing samples for and conducting multi-parameter flow cytometry\n• Ability to analyze data in spreadsheets\, data entry into databases\, database management\, advanced computer skills\n• Ability to draft routine reports and keep accurate records of work performed \n• Strong inclination to learn and apply new techniques\n• Ability to handle and prioritize responsibilities pertaining to multiple projects \n\n\nPreferred Qualifications \n• Understanding and research experience in the field of immunology\n• Experience handling and working with human tissues\n• Experience purifying PBMCs from blood\n• Experience in assisting team members\n• Coursework experience with nucleic acid amplification\, PCR\, cloning\n• General cell culture technique. Serial passage of cells\, transfection\, growth assays
URL:https://ces.b2sg.org/event/ucsf-22mar18/
LOCATION:UCSF\, 505 Parnassus Ave\, San Francisco\, CA\, 94143\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180322
DTEND;VALUE=DATE:20180424
DTSTAMP:20260821T163919
CREATED:20180322T102038Z
LAST-MODIFIED:20180322T102038Z
UID:19814-1521676800-1524527999@ces.b2sg.org
SUMMARY:Clinical Research Scientist
DESCRIPTION:This position is responsible for working with the physicians and cross functions within Clinical Development to provide clinical research support for programs as assigned by phase. \nResponsibilities \nIn collaboration with cross functional teams performs the following: \n\nDevelops protocols and informed consent documents for clinical studies\nAnalyzes and works with clinical data\nDrafts clinical scientific documents such as IND\, IND amendments\, Investigator Brochures\, and other documents for FDA/EMA submissions\nContributes actively in the CSR preparation and finalization\nMonitors\, & reviews along with the medical monitor safety and efficacy data in ongoing studies; monitors GCP compliance with help of clinical operations and CRO\nContributes to the development of CRFs\nAnswers along with the medical monitor patient eligibility questions from CRO and site and questions from IRB/EC and health authorities\nMay have a leadership role in the matrix teams for assigned compounds\nDevelops and maintains relationships with appropriate KOLs\, investigators\, cooperative groups\, and patient advocacies. Serves as first point of contact for medical questions from sites\nAssists and/or writes with clinical abstracts\, assists and/or presents data at scientific meetings\, SIVs; conducts protocol training\nParticipates with clinical operations in the CRO/vendor selection and bidding\nKeeps abreast of oncology treatment modalities\, drug mechanism of action\, approaches to drug development and regulatory requirements\nActs as a clinical representative in variety of cross-functional teams\n\nQualifications \n\nDegree in scientific/life-sciences/clinical/nursing field. M.S.\, Ph.D. preferred\nPrior hematology or oncology drug development experience is highly desired\nAbility to multi-task well\, to deal well with conflict and obstacles\, and to work in a fast-paced environment\nExcellent written and oral communication skills\nStrong analytical ability
URL:https://ces.b2sg.org/event/epizyme-22mar18/
LOCATION:Epizyme\, 400 Technology Square\, Cambridge\, MA\, 02139\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180323
DTEND;VALUE=DATE:20180425
DTSTAMP:20260821T163919
CREATED:20180323T093917Z
LAST-MODIFIED:20180323T093917Z
UID:19817-1521763200-1524614399@ces.b2sg.org
SUMMARY:Human Genetics/WCI Open Rank Faculty Position - Tenure Path
DESCRIPTION:We seek exceptional individuals with dynamic and innovative cancer research programs with a specific focus in cancer genetics\, epigenetics\, and/or genomics. Successful candidates will be expected to maintain an independent federally funded research program and to participate in cancer center activities. This recruiting effort is part of a strategic initiative to create a cadre of first class scientists with closely related research interests in support of Winship’s Cancer Genetics and Epigenetics Research Program.\n\n\nAdditional Details\n\n\nInterested candidates should submit a Cover Letter indicating his/her research interest\, Curriculum vitae\, Statement of research accomplishments and goals (2 pages)\, and names of 3 potential references.-Successful candidates will hold an PhD\, MD or MD/PhD degree\, postdoctoral training\, and a strong track-record of peer-reviewed research publications and extramural funding.  \nThe Winship Cancer Institute of Emory University (Winship) in partnership with the Department of Human Genetics (DOHG) at Emory University School of Medicine invites applications from outstanding candidates for a tenure-path faculty position at the rank of Assistant\, Associate\, or Full Professor\, commensurate with experience. We seek exceptional individuals with dynamic and innovative cancer research programs with a specific focus in cancer genetics\, epigenetics\, and/or genomics. Successful candidates will be expected to maintain an independent federally funded research program and to participate in cancer center activities. This recruiting effort is part of a strategic initiative to create a cadre of first class scientists with closely related research interests in support of Winship¿s Cancer Genetics and Epigenetics Research Program.-76239BR
URL:https://ces.b2sg.org/event/emory-23mar18/
LOCATION:Emory University\, 201 Dowman Dr\, Atlanta\, GA\, 30322\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180324
DTEND;VALUE=DATE:20180426
DTSTAMP:20260821T163919
CREATED:20180324T111104Z
LAST-MODIFIED:20180324T111104Z
UID:19821-1521849600-1524700799@ces.b2sg.org
SUMMARY:Research Technician - Cancer Epigenetics
DESCRIPTION:Dr. Xiaobing Shi’s laboratory in the Center for Epigenetics at Van Andel Research Institute is seeking to hire one Research Technician. The Shi lab is among the leading groups in the study of regulation and recognition of histone modifications. The current research focus of the laboratory is to identify and characterize novel epigenetic readers and to determine their roles in human cancer with the long-term goal to translate the knowledge to the clinic. Main techniques used in the lab include molecular and cellular biology\, biochemistry and biophysics\, genetic and genomics\, mammalian cell culture and mouse model. \nThe Research Technician is expected to be responsible for the following tasks: \n\nmolecular cloning\nsmall-scale protein expression and purification\nbasic biochemical assays and detection of protein-protein interactions\nbasic cell culture and maintenance\ngeneral lab maintenance\nOther lab duties as requested\n\nRequirements: \nCandidates need to have a Bachelor’s or preferably a Master’s degree in biological sciences in the fields of biochemistry\, molecular and/or cell biology. A minimum 2 years of hands on bench experience is required. A successful candidate will be a self-disciplined\, highly organized team worker. \nApplication Process: \nQualified applicants should provide a cover letter\, a curriculum vitae\, and the names and address of three references to xiaobing.shi@vai.org\, and applying online. \nIf you possess these attributes and desire to help us drive science from the bench to the clinic; while benefiting from a highly generous compensation package; we would welcome speaking with you and encourage you to apply today. \nVAI is actively striving to diversify its workforce and strongly encourages qualified individuals from underrepresented groups to apply. Van Andel Institute is an EEO and Affirmative Action Employer. \nThis position will be open until filled. If you have any difficulty uploading your application or any questions\, please email Eric Miller at eric.miller@vai.org.
URL:https://ces.b2sg.org/event/van-24mar18/
LOCATION:Van Adel Research Institute\, Grand Rapids\, MI\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180325
DTEND;VALUE=DATE:20180427
DTSTAMP:20260821T163919
CREATED:20180325T093311Z
LAST-MODIFIED:20180325T093311Z
UID:19823-1521936000-1524787199@ces.b2sg.org
SUMMARY:Post Doctoral Associate
DESCRIPTION:A postdoctoral position is available in the laboratory of Dr. Merav Socolovsky in the Department of Cancer Biology at the University of Massachusetts Medical School. We investigate the process of mammalian blood cell differentiation\, with a focus on epigenetics and the cell cycle. Please visit the Socolovsky Lab Website ( http://labs.umassmed.edu/socolovskylab/) for details on available research areas. \n\n\n\nQualifications\n\n\n\nApplicants should have a Ph.D. in Cell\, Developmental or Molecular Biology\, be creative and highly motivated. \n\n\n\nAdditional Information\n\n\n\n\n\nPlease send a brief statement of your scientific work and interests\, a CV and the name and email address of three references\, to Merav.socolovsky@umassmed.edu  
URL:https://ces.b2sg.org/event/umass-25mar18/
LOCATION:UMass Medical School\,  55 N Lake Ave\, Worcester\, MA\, 01655\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180326
DTEND;VALUE=DATE:20180428
DTSTAMP:20260821T163919
CREATED:20180326T092407Z
LAST-MODIFIED:20180326T092747Z
UID:19826-1522022400-1524873599@ces.b2sg.org
SUMMARY:Scientist – Translational Sciences
DESCRIPTION:Constellation Pharmaceuticals is a premier epigenetics company\, focused on the discovery and development of novel\, small molecules targeting chromatin regulatory proteins in tumor and immune cells for therapeutic applications in oncology. Our unique discovery platform integrates our understanding of chromatin-regulatory mechanisms with cancer and immune pathways to optimize our drug discovery activities and fully enable the clinical translation of our programs. \nThe Department of Translational Sciences at Constellation seeks a motivated Scientist to conduct research to support the advancement of portfolio small molecule inhibitors into clinical trials in targeted cancer indications and patient populations. The incumbent will identify predictive biomarkers for enrichment of patient populations most likely to respond to our agents in the clinic\, and pharmacodynamic biomarkers to monitor target engagement. The position requires expertise in cancer biology and/or chromatin biology\, and a passion to contribute to high quality scientific research to drive programs into the clinic. We are seeking a highly motivated\, independent\, and skilled candidate who will be responsible for planning\, execution\, interpretation and presentation of data to drive translational programs. \nThe primary responsibilities will include: \n\nKey contributor to translational science programs\, and delivery of scientific discoveries impacting decision-making at team meetings\nDesign and perform complex chromatin-focused experiments to support hypotheses around the biological functions and molecular mechanisms of oncology targets\nIdentification/validation of biological contexts that create a dependency on a given drug target to aid indication/context prioritization for clinical development. This entails both performing and guiding internal efforts\, as well as external efforts with CROs or collaborators.\nClosely work with bioinformatics group to use genomic\, epigenomic\, and/or transcriptomic data to generate novel biomarker hypotheses and identify novel biomarkers\nIdentification and clinical translation of biomarker assays that assess drug pharmacodynamics\, and allow testing of preclinical response hypotheses enabling differentiating path for small molecular inhibitor development\nBe part of a highly skilled translational team that shares a common goal of delivering optimal path forward for clinical development.\n\nRequirements: \n\nPh.D. in molecular or cellular biological sciences with emphasis on chromatin and/or cancer biology\, and 3-5 years of work experience (post-doctoral\, industry position or equivalent)\nBroad knowledge and laboratory research experience in oncology and/or epigenetics space as demonstrated by peer-reviewed publications\nFlexibility to work across diverse areas\, utilization of next-generation sequencing technologies and familiarity with using pathway analysis and bioinformatics data analysis software\nDetail-oriented\, self-motivated\, and ability to work independently\nStrong oral and written communication skills\, writing reports and giving updates at team meetings is required. The ability and desire to work in a challenging dynamic environment under tight deadlines is required
URL:https://ces.b2sg.org/event/const-26mar18/
LOCATION:Constellation Pharmaceuticals\, 215 First Street\, Cambridge\, MA\, 02142\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180328
DTEND;VALUE=DATE:20180430
DTSTAMP:20260821T163919
CREATED:20180328T103020Z
LAST-MODIFIED:20180328T103020Z
UID:19829-1522195200-1525046399@ces.b2sg.org
SUMMARY:Postdoctoral Fellow
DESCRIPTION:We are seeking one motivated postdoctoral fellow or research associate to study  \n1) The biology of Chimeric Antigen Receptor T ( CAR -T) and NK ( CAR -NK) cells and characterize these CAR -T and CAR -NK cells (Mol Ther. 2018\, PMID : 29503199) for development of innovative therapies for chronic viral infection and virus-related malignancies with the ultimate goal of administering them to patients as part of a future clinical trial.  \n2) The cell biology of NK cell\, with a focus on NK cell inhibitory receptor signaling (Immunity. 2012\, PMID : 22464172) and immunological synapse (Immunity\, 2009\, PMID : 19592272) using human NK cells and novel NK-specific knockout mice.  \nWe are using molecular\, biochemical\, immunological\, and imaging strategies\, as well as biophysical approaches for understanding human lymphocyte dysfunction in chronic infectious diseases and cancer.  \nAll applicants with experience in molecular & cell biology\, molecular cloning\, immunology\, or imaging are encouraged to apply.  \nThis post-doctoral fellowship will provide the opportunity to apply cutting-edge techniques to study the biology of cytotoxic lymphocytes and CAR -T and CAR -NK cells in the laboratory of Dongfang Liu.  \nHouston Methodist\, a teaching hospital affiliated with Weill Cornell Medical College\, Cornell University\, is located at the vibrant Texas Medical Center in Houston\, TX.  \nSalary will be commensurate with NIH post-doctoral pay scales.  \nPlease attach with your application\, a cover letter\, CV\, and contact information for 3 references to Dongfang Liu ( dliu2@houstonmethodist.org )
URL:https://ces.b2sg.org/event/hmri-28mar18/
LOCATION:Houston Methodist Research Institute\, 6670 Bertner Ave\, Houston\, TX\, 77030\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180330
DTEND;VALUE=DATE:20180501
DTSTAMP:20260821T163919
CREATED:20180330T161613Z
LAST-MODIFIED:20180330T161613Z
UID:19831-1522368000-1525132799@ces.b2sg.org
SUMMARY:Bioinformatics Research Scientist
DESCRIPTION:St. Jude Children’s Research Hospital’s Department of Tumor Cell Biology is looking for a highly motivated bioinformatics research scientist as the key analyst for the genomics and epigenomics projects of the Department of Tumor Cell Biology\, in close collaboration with the Department of Computational Biology. The goal of the Tumor Cell Biology department\, led by Dr. Charles J. Sherr\, an HHMI investigator\, is to understand how oncogenes\, tumor suppressors and checkpoint monitors of cellular stress govern tumor initiation\, progression\, and responses to cancer therapy.  Emphasis is placed on developing preclinical models of pediatric cancers\, including medulloblastoma and acute lymphoblastic leukemia to run pre-clinical trials to improve current therapies. Members of the Department of Tumor Cell Biology publish in high profile journals in Cancer Biology\, including Nature\, Cancer Cell\, Cancer Research and E-Life. The Computational Biology Department has a well-established track record in leading bioinformatics analysis for high-profile genomic and translational research projects such as the St. Jude/Washington University Pediatric Cancer Genome Project. Specific projects include the integrative analysis of ChIP-seq of histone marks and transcription factors\, ATAC-seq\, Hi-C\, Capture-seq\, whole-genome and whole exome sequencing\, whole transcriptome RNA-seq data to understand the mechanism of key molecular pathways involved in tumorigenesis especially medulloblastoma. Candidates with understanding of cancer genomics\, epigenomics and/or genetics\, strong problem solving skills\, attention to detail\, critical thinking\, and expertise in next-generation sequencing data analysis are highly encouraged to apply for this position. \nMinimum Experience\n\n\n\n\nPh.D which must include research related to bioinformatics (such as analysis of sequence data\, microarrays\, SNPs\, image data\, proteomics data\, or biological pathways; development of algorithms\, statistical methods\, or scientific software); OR If Ph.D with no bioinformatics research\, then two (2) years of pre-or postdoctoral experience in Computational Biology or Bioinformatics research is required\nExperience with programming languages such as Perl\, C\, or Java required\n\nPreferred skills:   \n\nExperience with Python and knowledge on statistical analysis package such as R and Matlab is highly desired. Experience in epigenetics analysis such as ChIP-seq\, ATAC-seq\, DNase I hypersensitivity-seq\, 4C-seq\, ChIA-PET\, WGS is preferred. Knowledge about neurobiology is also a plus.\n \n\n\n\n\nMinimum Education\n\n\n\n\nPh.D. in Molecular Biology\, Biochemistry\, Computer Science\, Statistics\, Mathematics\, Bioinformatics or related field required.\nPh.D. which must include research related to bioinformatics (such as analysis of sequence data\, microarrays\, SNPs\, image data\, proteomics data\, or biological pathways; development of algorithms\, statistical methods\, or scientific software). \nOR\nIf Ph.D. with no bioinformatics research\, then two (2) years of pre-or postdoctoral experience in Computational Biology or Bioinformatics research is required
URL:https://ces.b2sg.org/event/stjude-30mar18/
LOCATION:St. Jude Children’s Hospital\, 262 Danny Thomas Pl\, Memphis\, TN\, 38105\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180405
DTEND;VALUE=DATE:20180507
DTSTAMP:20260821T163919
CREATED:20180405T063526Z
LAST-MODIFIED:20180405T063712Z
UID:19833-1522886400-1525651199@ces.b2sg.org
SUMMARY:Postdoctoral Fellow - Cancer Genetics\, Epigenetics
DESCRIPTION:NCI-funded positions are available now for motivated\, creative post-doctoral candidates interested in fundamental molecular mechanisms ensuring genomic and epigenomic stability and how the mechanistic deficiency relate to cancer initiation\, progression\, and therapeutic intervention. For more scientific background\, please refer to our recent publications (Nature Medicine 13:812-819\, 2007; Nature Chem. Biol. 6:766-773\, 2010; Mol. Cell. 47:444-456\, 2012; EMBO J. 32:1425-1439\, 2013).  \nMinimum Education and Skills Required for Consideration:\nBoth new Ph.D. graduates and more established Ph.D.s with a solid background in molecular and cell biology or related fields are welcome to apply.  \nExcellent communication skills with the ability to work independently and as part of a team are a plus.  \nApplicants interested in innovative and integrative basic research with great interest and expertise in cancer genetics and epigenetics are strongly encouraged to apply. 
URL:https://ces.b2sg.org/event/hope-5apr18/
LOCATION:City of Hope\, 1500 East Duarte Road\, Duarte\, 91010\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180405
DTEND;VALUE=DATE:20180507
DTSTAMP:20260821T163919
CREATED:20180405T064846Z
LAST-MODIFIED:20180405T065022Z
UID:19837-1522886400-1525651199@ces.b2sg.org
SUMMARY:Associate Investigator
DESCRIPTION:The Associate Investigator is a self-sustaining Scientist and has achieved recognition in his/her field. The Associate Investigator heads a Laboratory and is responsible for the hiring\, training and management of his/her Lab personnel and for assuring that they work according to the Baylor Scott & White Research Institute (BSWRI) standards. While the Associate Investigator may receive supplemental funds from BSWRI\, it is the Investigator’s responsibility to obtain grants that will support his/her research and to produce data that is worthy of publication in leading journals and has patent potential. The Associate Investigator is part of the BSWRI faculty and plays a role in the continued growth and development of BSWRI. He/she may be asked to serve on committees\, develop collaborations or act as a liaison with external departments.  \nThe ideal candidate for the Associate Investigator role will be a PhD Scientist with a proven track record of leading a research team\, securing their own grants\, and consistently being published in their field. \n\nDoctorate Degree required\n4 years of experience required
URL:https://ces.b2sg.org/event/bsw-5apr18/
LOCATION:Baylor Scott & White Health (BSWH)\,  3500 Gaston Ave\, Dallas\, TX\, 75246-2017\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180406
DTEND;VALUE=DATE:20180508
DTSTAMP:20260821T163919
CREATED:20180406T074448Z
LAST-MODIFIED:20180406T074950Z
UID:19840-1522972800-1525737599@ces.b2sg.org
SUMMARY:Postdoctoral Fellow
DESCRIPTION:A Postdoctoral Fellow position is available in Dr. Chuong Dinh Hoang’s laboratory within the Thoracic and Gastrointestinal Oncology Branch (TGIB) \, National Cancer Institute\, NIH.  \nOur broad goal is to explore the molecular and cellular biology of thoracic cancers\, namely mesothelioma and/ or non-small cell lung carcinoma\, thymoma\, etc. Currently\, we have projects that involve investigating microRNA-mRNA interactions in malignant mesothelioma. New projects will focus on the pathogenic signaling pathways relevant to tumor initiation\, invasion\, metastasis\, and resistance. With these projects\, we have translational aims of developing novel molecular biomarkers and therapeutic targets based on an understanding of the pathogenetic mechanisms active in these cancers. Also\, we are developing novel delivery platforms for nucleic-based agents that require pre-clinical testing in mouse tumor models. The culmination of these projects will be linked to clinical human protocols in these thoracic cancers of interest.  \nThis is a great opportunity for candidates who are interested in cancer biology and want to enhance their career potential by working in our research program with outstanding support of other established laboratories and core facilities in the National Cancer Institute. This laboratory effort will be in close collaboration with other faculty in our branch. We work closely with the Thoracic Oncology Section of David S. Schrump\, M.D. (Chief\, TGIB)\, which focuses on epigenetic mechanisms and regulation of thoracic tumors; and with the lab of Dr. Taylor Ripley\, M.D. \, which focuses on metabolism of thoracic tumors.  \nExperience Required: \nQualified candidates should have a Ph.D. in a biological science area or the equivalent background (M.D.\, M.B.B.S.\, etc.) with one to five years of postdoctoral experience. A background and working knowledge in molecular and cellular biology is required. Familiarity with basic techniques including DNA/ RNA isolation\, cell culture techniques Western-blot\, quantitative PCR\, immunohistochemistry\, ChIP\, retroviral or lentiviral transfections\, FACS sorting\, and working with mice are a must. Knowledge and/or experience in bioinformatics\, biostatistics\, mutation detection\, microarray analysis\, RNA-seq and other sequencing methodology\, and microRNA is preferred. Previous research experience in cancer or stem cell biology is advantageous\, but not required.
URL:https://ces.b2sg.org/event/nih-6apr18/
LOCATION:National Institutes of Health (NIH) campus\, Bethesda\, MD\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180406
DTEND;VALUE=DATE:20180508
DTSTAMP:20260821T163919
CREATED:20180406T085910Z
LAST-MODIFIED:20180406T085910Z
UID:19844-1522972800-1525737599@ces.b2sg.org
SUMMARY:Post-Doctoral Research Fellow
DESCRIPTION:The Program in Prostate Cancer Research and the Division of Human Biology seeks a Postdoctoral Fellow to perform studies exploring the molecular mechanisms underlying metastatic prostate cancer.\nThe particular areas of emphasis for this position center on studies of cancer genomics\, epigenetics\, cell-free DNA\, prostate cancer biomarkers\, and treatment strategies. We are recruiting a post-doctoral fellow to engage in laboratory-based studies of these processes. This is a basic science position that focuses on delineating the molecular mechanisms of metastatic prostate cancer with the opportunity for translational studies evaluating the efficacy and outcome of novel therapeutics.\n\n\n\nQualifications\n\n\n\nPh.D. degree in biology; biochemistry; genetics; molecular biology; cell biology; immunology or related field is required. Additionally\, experience in one of the following areas is required: genomics/genetics\, analysis of inflammation/immune composition\, biomarker characterization. Knowledge/exposure in biobanking\, clinical trial design\, and biostatistics is desired\, as well as a demonstrated track record of high-quality publications. Expertise/skills in molecular biology techniques is required: RT-PCR\, immunohistochemistry\, ELISA\, cell culture\, drug toxicity assays. Candidates need to be highly-motivated\, organized individuals who think independently but enjoy working as part of a dynamic\, collaborative\, and multidisciplinary team. Excellent verbal and written communication skills are essential.
URL:https://ces.b2sg.org/event/fh-6apr18/
LOCATION:Fred Hutchinson Cancer Research Center
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180406
DTEND;VALUE=DATE:20180508
DTSTAMP:20260821T163919
CREATED:20180406T091115Z
LAST-MODIFIED:20180406T105243Z
UID:19846-1522972800-1525737599@ces.b2sg.org
SUMMARY:Faculty Position in Biochemistry
DESCRIPTION:The Biochemistry and Molecular Genetics Department at Northwestern University Feinberg School of Medicine seeks a full-time tenure track Investigator at the rank of Assistant\, Associate or full Professor. \nNorthwestern University Feinberg School of Medicine has committed substantial resources toward expanding interdisciplinary research in the Biochemistry and Molecular Genetics Department. A new Department of Biochemistry and Molecular Genetics\, with founding faculty members from the Department of Molecular Pharmacology and Biological Chemistry\, is led by Dr. Ali Shilatifard\, an internationally recognized leader in chromatin biology\, gene expression and epigenetics\, and on how the misregulation of these pathways contributes to human cancer. We are now seeking candidates to fill a new full-time\, tenure track faculty position at the Assistant\, Associate\, or full Professor rank. Northwestern University offers a collegial and collaborative scientific environment that is rich with core facilities\, robust cross-disciplinary graduate training programs\, and diverse expertise. \nCandidates should have a PhD\, MD/PhD or MD degree\, significant research experience\, and evidence of sustainable extramural funding. Salary is commensurate with experience. The start date is negotiable and applications will be accepted until the position is filled. \nPlease read ALL instructions and make preparations before proceeding to the application page: \n\nApplications will only be accepted via online submission (see link below).\nPlease prepare all documents in advance as Adobe PDF files\, and please be sure all information is entered correctly and accurately (especially names and email addresses)\, as there will be no opportunity for online revision after your application has been submitted.\nAll required fields in the application form are marked with an asterisk and must be filled before clicking the “Submit” button.\nBe aware that incomplete applications cannot be saved.
URL:https://ces.b2sg.org/event/nwu-6apr18/
LOCATION:Northwestern University\, 633 Clark St\, Evanston\, IL\, 60208\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180407
DTEND;VALUE=DATE:20180509
DTSTAMP:20260821T163919
CREATED:20180407T084021Z
LAST-MODIFIED:20180407T084056Z
UID:19851-1523059200-1525823999@ces.b2sg.org
SUMMARY:Post Doctoral Associate
DESCRIPTION:Postdoctoral Position in Epigenetics\, the Cell Cycle and Hematopoiesis at the University of Massachusetts Medical School\n\n\n\nResponsibilities\n\n\n\nA postdoctoral position is available in the laboratory of Dr. Merav Socolovsky in the Department of Cancer Biology at the University of Massachusetts Medical School. We investigate the process of mammalian blood cell differentiation\, with a focus on epigenetics and the cell cycle. Please visit the Socolovsky Lab Website ( http://labs.umassmed.edu/socolovskylab/) for details on available research areas.\n\n\n\nQualifications\n\n\n\nApplicants should have a Ph.D. in Cell\, Developmental or Molecular Biology\, be creative and highly motivated.\n\n\n\nAdditional Information\n\n\n\n\n\nPlease send a brief statement of your scientific work and interests\, a CV and the name and email address of three references\, to Merav.socolovsky@umassmed.edu\n\n\n\n\n\n(Please do not apply via the UMMS Career Site)
URL:https://ces.b2sg.org/event/umms-7apr18/
LOCATION:UMass Medical School\,  55 N Lake Ave\, Worcester\, MA\, 01655\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180407
DTEND;VALUE=DATE:20180509
DTSTAMP:20260821T163919
CREATED:20180407T084819Z
LAST-MODIFIED:20180407T084819Z
UID:19853-1523059200-1525823999@ces.b2sg.org
SUMMARY:Research Fellow
DESCRIPTION:Two fully funded post-doctoral positions are available in the lab of Dr. Carl Novina in the Cancer Immunology and Virology Program at Dana-Farber Cancer Institute (http://novinalab.dana-farber.org/). The positions are available for the translation of (1) autologous T cell therapies for solid tumors including chimeric antigen receptors (CAR-T cells) and (2) targeted epigenetic reprogramming of immune cells.\nSuccessful candidates will work in a collaborative and entrepreneurial team of researchers and clinicians to develop and evaluate the efficacy of novel cell and molecular therapies.\nInterested individuals should submit a cover letter and curriculum vitae and contact information for three references.\n\n\n\nQualifications\n\n\n\nCandidates should have a PhD or MD/PhD in immunology or a related field and at least one first author peer-reviewed publications\, with significant experience in standard immunological assays. Expertise in neuroimmunology\, immunotherapy\, and/or human immunobiolgy preferred.
URL:https://ces.b2sg.org/event/df-7apr18/
LOCATION:Dana-Farber Cancer Institute\, 450 Brookline Avenue\, Boston\, MA\, 02215\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180410
DTEND;VALUE=DATE:20180512
DTSTAMP:20260821T163919
CREATED:20180410T153027Z
LAST-MODIFIED:20180506T084356Z
UID:19855-1523318400-1526083199@ces.b2sg.org
SUMMARY:Postdoctoral Fellow - Skeletal Disease
DESCRIPTION:We are looking for a motivated and collaborative postdoctoral fellow to join the lab of Dr. Tao Yang at Van Andel Research Institute in Grand Rapids\, MI. \nThe Yang Laboratory is interested in the mechanisms regulating skeletal physiology and disease development\, with an emphasis on skeletal stem cell/progenitors differentiation and pool maintenance. A combined approach using in vivo and in vitro models allows the lab to study the molecular mechanisms underlying osteoarthritis\, osteoporosis\, and bone tumors. \nThis postdoctoral position is available IMMEDIATELY and is for a motivated scientist who meets the qualifications and description outlined below. This fellow will investigate the novel mechanisms of sumoylation pathways in mesenchymal stem cell stemness\, differentiation\, and maintenance during skeletal aging and diseases. A few intriguing phenotypes of these genetic mouse models have been established in our genetic mouse models awaiting mechanistic and translational studies. \nQualifications: \n\nA Ph.D. or M.D./Ph.D. in molecular and cell biology\, developmental biology\, and/or biochemistry.\nExperience with genetic mouse models\, stem cell biology\, skeletal biology\, epigenetics\, and/or cancer biology is preferred.\nA strong record of peer-reviewed publication is highly desirable.\n\nInterested applicants should apply online AND send a cover letter describing research experience and interests\, a CV\, and contact information of three references to tao.yang@vai.org. \nIf you have any difficulty uploading your application or any questions\, please email Eric Miller at eric.miller@vai.org.
URL:https://ces.b2sg.org/event/vari-10apr18/
LOCATION:Van Adel Research Institute\, Grand Rapids\, MI\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180410
DTEND;VALUE=DATE:20180513
DTSTAMP:20260821T163919
CREATED:20180410T161133Z
LAST-MODIFIED:20180508T101237Z
UID:19857-1523318400-1526169599@ces.b2sg.org
SUMMARY:Research Fellow
DESCRIPTION:A Research Fellow position is available in the program of Dr. Keith Robertson. For more information about Dr. Robertson’s program\, please see: http://www.mayo.edu/research/faculty/robertson-keith-d-ph-d/bio-20035097 \nThe successful candidate will join the Epigenetic Etiology of Human Disease Laboratory to study the role of DNA epigenetic modifications in human disease. More specifically\, he/she will examine how DNA methylating and hydroxymethylating enzymes regulate their respective DNA epigenetic modifications and how these marks modulate expression and genome stability\, and interface with other epigenetic modifications. Disease focus areas of the laboratory include cancer (hepatocellular and renal)\, obesity\, and diabetes. Specific research areas include application of genome-wide epigenomics methods to decipher DNA methylation/hydroxymethylation defects in cancer and biochemical/cell culture-based techniques to study the regulation and interactions between chromatin remodeling factors (e.g. DNMTs\, TETs\, HMTases) and the roles of their target loci in driving disease. Techniques commonly used in the laboratory include: quantitative RT-PCR\, western blotting\, cell culture\, transfections\, bisulfite sequencing\, DNA immunoprecipitation\, pyrosequencing\, ChIP-qPCR\, ChIP-seq\, next-gen library preparation and sequencing\, Infinium 850k arrays\, bioinformatics analysis\, microscopy\, and biochemical analysis of protein function. Experience in one or more of these areas is a plus. The candidate will play a major role in the preparation of manuscripts that arise from this work and devote 100% effort to these tasks (no patient contact or other responsibilities). \nPosition description \nA Research Fellow at Mayo Clinic is a temporary position intended to provide training and education in research. Individuals will train in the research program of a Mayo Clinic principal investigator. Qualified individuals will demonstrate the potential for research as evidenced by their training and peer-reviewed publications and should become competitive for national research grants. Proof of English proficiency is required for J-1 Short-Term Scholars\, Research Scholars\, Professors\, Specialists\, and Student Interns sponsored by Mayo Clinic. 800146; J2WRTP \nQualifications \nMust have a Ph.D.\, M.D.\, or equivalent doctoral degree in a field deemed relevant by the program. Research Fellow is appropriate for individuals who have completed no more than one prior postdoctoral fellowship\, at Mayo Clinic or elsewhere. Please attach the following required documents at the time of application: \n\nCurrent curriculum vitae and bibliography\nThree letters of recommendation\, signed\, on letterhead\, describing:\n\nRelationship to the applicant.\nPast work/academic performance.\nWork qualities/personal conduct.\nOverall assessment of potential for success in research environment.\n\n\nDoctoral degree certification\, if applicable:\n\nOriginal or notarized copy of diploma or final transcript issued by school (English translation required).
URL:https://ces.b2sg.org/event/mayo-10apr18/
LOCATION:Mayo Clinic\, 200 1st St SW\, Rochester\, MN\, 55905\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180410
DTEND;VALUE=DATE:20180513
DTSTAMP:20260821T163919
CREATED:20180410T163514Z
LAST-MODIFIED:20180508T102102Z
UID:19860-1523318400-1526169599@ces.b2sg.org
SUMMARY:Senior Scientist/Principal Scientist - Computational Biology
DESCRIPTION:he Senior Scientist /Principal Scientist leads the identification and incorporation of new technologies or best practices to enhance a specific scientific or technical area and/or leads a portfolio project. She/he also identifies and proposes external collaborations.\n\nIn the Bioinformatics Expert role\, the incumbent works as a member of Cross-Functional Project Teams and contributes to the discovery of First-in-Class or Breakthrough drugs. Evaluate\, acquire/develop\, and champion the use of genomics data and bioinformatics tools as a foundation to drive innovation in the BI portfolio. Support new therapeutic concept (NTC) discovery\, proof of clinical principal (PoCP)\, and mechanism of action (MOA) studies. Lead/contribute to disease and mechanistic model characterization to expand the role of genes\, pathways\, and cell types in the pathogenesis\nAs an employee of Boehringer Ingelheim\, you will actively contribute to the discovery\, development and delivery of our products to our patients and customers. Our global presence provides opportunity for all employees to collaborate internationally\, offering visibility and opportunity to directly contribute to the companies’ success. We realize that our strength and competitive advantage lie with our people. We support our employees in a number of ways to foster a healthy working environment\, meaningful work\, diversity and inclusion\, mobility\, networking and work-life balance. Our competitive compensation and benefit programs reflect Boehringer Ingelheim’s high regard for our employees\nDuties & Responsibilities:\n\nDevelopment of Analysis Plans in close collaboration with the TA Partner\, by 1)providing conceptual input into analysis plans (approaches and experimental design)\, and 2)engaging in cross-functional discussions to refine plans and identify key priorities\nCompletes bioinformatics data analysis as specified by analysis plans\, and provides interpretation and context to results of analysis\nIdentify\, evaluate\, and apply new methodologies and emerging technologies\, and develop software tools when appropriate\, to contribute to projects across TAs\nDemonstrate a high level of AAI capabilities by taking the initiative without waiting for direction\, working with a sense of urgency to discover breakthrough medicines that will improve patients’ lives\, sharing ideas beyond own team\, and challenging the status quo\n\nSenior Scientist Requirements:\n\nPh.D. degree or equivalent from an accredited institution in biological\, statistical\, computational\, or other quantitative science.\nTwo (2) or more years of relevant experience in drug discovery or biomedical research environment after completing a doctoral degree.\nIs a locally recognized science and/or technology subject matter expert within his/her department who develops and implements experimental approaches that contribute to department/Discovery Research goals by demonstrating expert knowledge to advance the portfolio. The development of a strong publication record within his/her expertise area is expected.\nExperience with experiment design\, and hands-on NGS (RNAseq\, single-cell NGS\, whole genome\, exome\, miRNA\, or mcrobiome) data processing and analysis.\nExperience in biological pathways\, data visualization\, network and systems biology (GSEA\, GeneGO\, CBDD\, Cytoscape\, Reactome).\nProficiency using R and Bioconductor packages and one or more programming language (Python\, Perl\, and Javascript).\nTrack record of designing\, leading\, and managing computational research projects.\nBackground in or familiarity with gene expression data (microarray\, RNA seq) analysis and biological interpretation.\nUnderstanding of biology of the diseases relevant to at least one of the TAs in Ridgefield (I&R\, CMDR\, and Cancer Immunology).\nExcellent communication and presentation skills.\nExperience working with patient-centric data\, GWAS\, and eQTL analysis is desirable.\nExperience working with Linux environment\, high performance computing clusters\, and cloud computing.\nIs a recognized expert in an area of genomics\, proteomics\, epigenetics\, and/or other high dimensional data analysis; always up-to-date with the latest methods developments in the field; fully understands internal capabilities in the area\, as well as external capabilities (service providers as well as academics and collaborators)\nProvides expert-level scientific and bioinformatics expertise within the area(s) of biology and human disease addressed by the TAs. Knowledge of current key datasets\, therapeutic landscape and demographic/epidemiological considerations within TA is required.\nComply with all company policies\, and maintain high quality of data and analyses (consistency checks at the logical and scientific level are implemented)\n\n\nPrincipal Scientist Requirements: \n\nPh.D. degree or equivalent from an accredited institution in biological\, statistical\, computational\, or other quantitative science.\nFive (5) or more years of relevant experience in drug discovery or biomedical research environment after completing a doctoral degree\, with at least two (2) years’ experience in drug discovery.\nIs a recognized science and/or technology subject matter expert across BI with a sustained publication and external presentation record.\nShe/he identifies new methodologies\, protocols and/or test procedures that contribute to department and Discovery Research goals and proactively proposes creative solutions to department or Discovery Research leadership.\nExperience with experiment design\, and hands-on NGS (RNAseq\, single-cell NGS\, whole genome\, exome\, miRNA\, or mcrobiome) data processing and analysis.\nExperience in biological pathways\, data visualization\, network and systems biology (GSEA\, GeneGO\, CBDD\, Cytoscape\, Reactome).\nProficiency using R and Bioconductor packages and one or more programming language (Python\, Perl\, and Javascript).\nTrack record of designing\, leading\, and managing computational research projects.\nBackground in or familiarity with gene expression data (microarray\, RNA seq) analysis and biological interpretation.\nUnderstanding of biology of the diseases relevant to at least one of the TAs in Ridgefield (I&R\, CMDR\, and Cancer Immunology).\nExcellent communication and presentation skills.\nExperience working with patient-centric data\, GWAS\, and eQTL analysis is desirable.\nExperience working with Linux environment\, high performance computing clusters\, and cloud computing.\nIs a recognized expert in an area of genomics\, proteomics\, epigenetics\, and/or other high dimensional data analysis; always up-to-date with the latest methods developments in the field; fully understands internal capabilities in the area\, as well as external capabilities (service providers as well as academics and collaborators)\nProvides expert-level scientific and bioinformatics expertise within the area(s) of biology and human disease addressed by the TAs.\nKnowledge of current key datasets\, therapeutic landscape and demographic/epidemiological considerations within TA is required.\nComply with all company policies\, and maintain high quality of data and analyses (consistency checks at the logical and scientific level are implemented)\n\n\nEligibility Requirements:\n\nMust be legally authorized to work in the United States without restriction.\nMust be willing to take a drug test and post-offer physical (if required)\nMust be 18 years of age or older
URL:https://ces.b2sg.org/event/boehringer-10apr18/
LOCATION:Boehringer Ingelheim\, Ridgefield\, CT\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180412
DTEND;VALUE=DATE:20180515
DTSTAMP:20260821T163919
CREATED:20180412T155933Z
LAST-MODIFIED:20180412T155933Z
UID:19865-1523491200-1526342399@ces.b2sg.org
SUMMARY:Senior Scientific Researcher
DESCRIPTION:We are seeking a Senior Scientific Researcher in the Department of Molecular Biology to support the production and optimization of genetically-modified cellular models. This position will be within the newly-established Cell Engineering Lab\, wherein she/he will facilitate the design\, execution\, and validation of cell line engineering projects initiated by researchers across Genentech – with the ultimate goal of generating more effective in vitro/ex vivo disease models and novel contexts for functional genomic screening. The candidate is expected to work creatively and independently within an extremely dynamic\, collaborative research environment. \nWho You Are\nA self-motivated candidate with a PhD in Genetics\, Molecular Biology\, Biochemistry\, Cancer Biology\, or a related discipline. Qualified candidates will have a skillset demonstrating successful\, documented application of molecular genetics/genome engineering either in cell-based systems or model organisms. Preferred expertise includes some or all of the following: DNA nucleases\, 2D and 3D cell culture\, RNA interference (siRNA/shRNA)\, reporter gene assays\, primary and/or stem cell models\, molecular cloning\, RNA/DNA/protein quantification\, epigenetics\, and viral vector development/use. Working knowledge of pooled vector-based screening\, Next-Gen Sequencing (NGS)\, biostatistics\, and/or basic bioinformatics is desirable. The successful candidate will be team-oriented\, highly organized\, and have excellent communication skills\, both written and verbal. \n\nLI-gRED-JM1
URL:https://ces.b2sg.org/event/genentech-12apr18/
LOCATION:Genentech\, 1 DNA Way\, South San Francisco\, CA\, 94080\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180416
DTEND;VALUE=DATE:20180518
DTSTAMP:20260821T163919
CREATED:20180416T094059Z
LAST-MODIFIED:20180416T094059Z
UID:19868-1523836800-1526601599@ces.b2sg.org
SUMMARY:Postdoctoral Fellows
DESCRIPTION:An NIH -supported postdoctoral fellow position is available immediately in Dr. Byungwoo Ryu’s laboratory at the Boston University School of Medicine. Creative and self-motivated candidates with Ph.D. in medical science/cancer biology\, biochemistry\, and molecular biology (received with a few years or close to be awarded) are encouraged to make initial contact to Dr. Byungwoo Ryu at ryub@bu.edu. These positions will focus on the interrogation of underlying epigenetic mechanisms of tumorigenesis and discovery of noble epigenetic targets for therapy in melanoma and other cancers. The projects use experimental approaches in chemical genetics\, proteomics\, epigenomics\, computational and system biology\, advanced gene editing\, and whole animal handling as well as traditional molecular\, cellular\, and biochemical methodologies. Experience in any of these areas is a merit\, but mastery of other advanced research techniques will be considered as evidence of an ability to learn skills needed in the projects. The candidates will have the ability to work both independently and as a part of team. \n\nRequired Skills \nDO NOT APPLY THROUGH THE BOSTON UNIVERSITY HR WEBSITE. \nInitial application by email should include: \n1) A cover letter stating your education and research backgrounds\, long-term career goals\, an explanation of how a fellowship in this lab will help achieve those goals\, evidence of scientific productivity (two or three recently published first-author papers)\, and visa/immigration status \n2) A complete CV \n3) A short list of references (two or three) whom I may contact.
URL:https://ces.b2sg.org/event/boston-16apr18/
LOCATION:Boston University\, Boston\, MA\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180417
DTEND;VALUE=DATE:20180519
DTSTAMP:20260821T163919
CREATED:20180417T124241Z
LAST-MODIFIED:20180417T124241Z
UID:19871-1523923200-1526687999@ces.b2sg.org
SUMMARY:Senior Scientist - Toxicology
DESCRIPTION:The Senior Scientist\, Toxicology reports to the Head of Nonclinical Development and serves as an integral contributor to all the nonclinical development projects at Epizyme. The Senior Scientist provides expertise and advice to guide the activities of a project\, and provides scientific/technical expertise. Viewed as expert in the field within the department. Accountable for the development and implementation of solutions to problems. May develop new approaches and applications of programs and systems to lead processes in a new direction. Works independently toward goals and objectives of the department. \nResponsibilities \n\nExecution of nonclinical safety evaluations to further drug discovery and development objectives\nDevelop\, and execute nonclinical safety development plans from discovery through late stage clinical development programs\nParticipation on discovery and development teams\nCommunication and collaboration with program teams and across functions (e.g. Biology\, Clinical\, DMPK\, Medicinal Chemistry\, CMC\, etc.) to allow successful management of toxicology plans\nFrequent contacts with functional area leads and outside collaborators. Represents toxicology group in providing solutions to difficult technical issues associated with specific projects.\nProvide strategic advice for drug development programs\nPreparation of nonclinical safety assessment portions of regulatory documents\nManage toxicology contract research organizations (CROs): i.e. selection\, evaluations\, timelines\, communication\, monitoring and budget\nDesign toxicology study protocols\, monitor and review studies conducted at CROs\, provide integrated data evaluation and interpretation\nCommunicate nonclinical safety data with the proper perspective to appropriate team and management forums within Epizyme and to external partners\, as appropriate\n\nRequirements \n\nMS/PhD in toxicology or related field with a minimum 5-7 years’ industry experience\, Strong scientific background in pharmacology and toxicology\, In depth knowledge of nonclinical drug development and regulatory requirements\nStrong organizational skills\, ability to multi-task\, flexible to change\nSuperior communication skills (both written and oral)\, attention to detail\, and good questioning and analysis techniques desired\nDemonstrated ability to continually expand knowledge base and open to learning from\nothers\nGoal oriented\, highly self-motivated and self-directing individual who enjoys working in different environments and multiple capacities\nDemonstrated ability to work collaboratively with various functional areas\nExperience with contracting CRO studies and effective communication with CROs to enable a quality working relationship\, resulting in a quality product/report\nMust work effectively in a team environment and with individuals at all levels within an organization\nExperienced in preparation and review of regulatory documents\nSome travel required
URL:https://ces.b2sg.org/event/epizyme-17apr18/
LOCATION:Epizyme\, 400 Technology Square\, Cambridge\, MA\, 02139\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180417
DTEND;VALUE=DATE:20180519
DTSTAMP:20260821T163919
CREATED:20180417T133138Z
LAST-MODIFIED:20180417T133309Z
UID:19873-1523923200-1526687999@ces.b2sg.org
SUMMARY:Research Technician
DESCRIPTION:VARI has recently established a research program in metabolism and nutrition\, with the goal of improving health through prediction\, prevention\, diagnosis\, and treatment.   \n\nConnie Krawczyk.\, Ph.D.\, will be joining VARI in the summer of 2018 and is seeking to hire a full-time Research Technician in her lab. Dr. Krawczyk’s research focuses on the following areas: \n\n\nElucidate how immunological signals\, metabolism and cellular programming regulate the balance between protective and pathological inflammation.\nIdentify epigenetic reinforcements of immune states and their impact on disease development\nAdvance understanding of the interplay between the immune and nervous systems\,\nAdvance the understanding of the molecular mechanism that drive differences in susceptibility between males and females to inflammation and associated diseases\nExploring the therapeutic potential of targeting such mechanisms to treat inflammatory conditions such as cancer\, infection\, autoimmunity and neuroinflammation.\n\n\nIn this role as a Research Technician\, you will be instrumental in transitioning her lab\, currently located in Montreal Canada\, at McGill’s University to Grand Rapids\, MI to Van Andel Research Institute (VARI). This will include traveling to Montreal for a time period still to be determined. \n\nIn addition to assisting in with the lab relocation\, you should have an intense curiosity of biology\, and must possess the following:   \n\n\nTissue culture of primary cells and cell lines\nAnimal colony maintenance\, genotyping\, tissue harvesting\nInfection models in mice\nFlow cytometry\nmolecular cloning\ngenerate retrovirus and transduction of cells\nwestern blot\nchromatin immunoprecipitation and ATAC sequencing\nRNA isolation\, qRT-PCR\nELISA\ngeneral lab maintenance\ncellular metabolism – including seahorse\, mass spec\n\n\nThis list will change as projects evolve and you be open-minded to learn new things. \n\nYou will possess a Bachelor’s or Master’s degree in biological sciences\, focusing on immunology\, biochemistry\, molecular and cell biology and have 2 – 5 years of hands on bench experience. We are ideally looking for people with the following: \n\n\nHands on experience with cell culture work\, preferably experience with primary cell\nHands on experience with molecular cloning including\, primer design\, PCR\, mutagenesis\, etc…\nHands on experience with chromatin IP\nExperience and/or interest in bioinformatics\nA self-driven and hard-working individual who has a strong curiosity about basic science and its clinical application\nA highly organized multi-tasker who pays attention to detail and values research integrity\nA collegial team member with the ability to interact effectively and cordially with colleagues and collaborators\n\n  \nEXPECTATIONS \n  \nThe following expectations should be met within the first 3 months. \n\n\n1 month – Develop a solid understanding of the project\, master the techniques involved\, help transition the lab to VARI and generate new data\n\n\n3 months – Complete lab move to VARI\, acquire significant data\, and begin to take lead of the project\n\n\n\nHOW TO APPLY \nIf you possess these attributes and enjoy working with motivated and driven people\, we would welcome speaking with you and encourage you to apply today!  \n\n\nA cover letter describing your research interests\, experience\, and how you might contribute to Krawczyk Lab Research.\n\n\nAn up-to-date Curriculum Vitae.\n\n\nA list of 2-3 individuals who have agreed to act as references along with their contact details.\n\n\nPlease contact Eric Miller (eric.miller@vai.org) for further information or questions\, or if you have any difficulty with the application process.
URL:https://ces.b2sg.org/event/vari-17apr18/
LOCATION:Van Adel Research Institute\, Grand Rapids\, MI\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180418
DTEND;VALUE=DATE:20180520
DTSTAMP:20260821T163919
CREATED:20180418T091246Z
LAST-MODIFIED:20180418T091427Z
UID:19875-1524009600-1526774399@ces.b2sg.org
SUMMARY:Program Co-Leader - CMG
DESCRIPTION:The Virginia Commonwealth University (VCU) School of Medicine and Massey Cancer Center are seeking a successful scientist and leader to serve as the Program Co-Leader of the Cancer Molecular Genetics (CMG) research program at the cancer center. The CMG program consists of a multidisciplinary group of 26 investigators from 12 academic departments representing four schools. This tenure-eligible faculty position will be a key member of Massey’s leadership team. Responsibilities: \n-Provide oversight\, development\, implementation and evaluation of cancer molecular genetics related programs and initiatives at Massey Cancer Center \n-Partner with the Director\, Associate Directors and other Program Leaders at Massey to enhance the cancer center’s scientific goals and objectives \n-Work closely with leadership to encourage and facilitate multidisciplinary collaboration and translational research at the cancer center \n-Conduct fundamental research that can be translated into improved approaches for diagnosis\, prevention\, and treatment of neoplastic diseases Research can include but not limited to the following areas: -Epigenetic mechanisms in cancer development and progression: Understanding the regulation and interaction of histone modifications and other epigenetic controls including DNA methylation and miRNA; recognition of these post-translational modifications in DNA-chromatin complexes by nucleosome remodeling factors\, and the role of miRNA in these processes \n-Definition of the functional significance of genes involved in cancer development and progression\, and exploiting this information to identify and validate promising targets \n-Definition of the pathways that delete and silence tumor suppressor genes in human cancers \n\n\n\n\nMinimum Qualifications \n-PhD or MD/PhD \n-Area of cancer research expertise in epigenetics or epigenomics \n-Solid track record of scientific achievement reflected by both sustained and recent impactful publications and extramural peer-reviewed research funding in cancer related research as a Principal Investigator \n\n\n\n\nPreferred Qualifications \n-Proven leadership\, relationship building\, and strong communication skills \n-Experience working in a matrix environment within academic medicine \n-Proven success in collaborating with multi-disciplinary teams \n-Demonstrated experience working with and fostering diverse faculty\, staff\, and student environment or commitment to do so as a faculty member at VCU \n\n\n\n\nSpecial Requirements \nThe Program Co-Leader\, Cancer Molecular Genetics is responsible for the oversight\, development\, implementation and evaluation of the cancer molecular genetics related programs and initiatives at Massey Cancer Center.
URL:https://ces.b2sg.org/event/vcu-18apr18/
LOCATION:Virginia Commonwealth University\, 907 Floyd Ave\, Richmond\, VA\, 23284\, United States
CATEGORIES:Jobs
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DTSTART;VALUE=DATE:20180418
DTEND;VALUE=DATE:20180520
DTSTAMP:20260821T163919
CREATED:20180418T092924Z
LAST-MODIFIED:20180418T092924Z
UID:19879-1524009600-1526774399@ces.b2sg.org
SUMMARY:Sr. Research Associate 2
DESCRIPTION:The Senior Research Associate 2 (second level research position\, track one) supports research activities under the direction of a principle investigator\, program director or designee of the principle investigator or program director. Contributes to basic and applied research activities by collecting and analyzing data\, maintaining databases etc. Understands and interprets research protocols and procedures. Participates in the publication of significant results\, to include authorship of scientific monographs. Advances expertise through continued education\, training and/or research. Maintains an overview of relevant research findings. Ensures all research is undertaken according to good research practice and guidance. Responsibilities: Plan and conduct assigned and/or original research projects autonomously while working collaboratively with UM faculty\, staff\, postdocs and students. Maintain accurate records of research findings and the analysis of results. Prepare manuscripts for publication in collaboration with UM faculty\, staff\, postdocs\, and students. Present research findings at professional meetings. • Mentor graduate and undergraduate students as appropriate. Responsible for assisting graduate and undergraduate students in area of expertise. Other duties as assigned.  \nThe minimum qualifications are: Master’s in relevant discipline in cell/molecular biology\, immunology\, stem cell or leukemia research. Must have broad knowledge of hematological malignancy or related fields of cancer research as well as experience in human cell/tissue culture\, molecular biological techniques\, experimental experience with animal models\, studies in epigenetics\, and experience in cancer research. Ability to plan\, organize and meet deadline; highly motivated\, must be detail oriented\, self-starter with strong interpersonal skills. Knowledge of PC software programs: Word\, Excel\, and PowerPoint. Need the ability to manage multiple tasks simultaneously and independently. Must be able to apply logic and demonstrate problem solving techniques. Must have excellent verbal and written communication and presentation skills. 
URL:https://ces.b2sg.org/event/umiami-18apr18/
LOCATION:University of Miami\, 1320 S Dixie Hwy\, Coral Gables\, FL\, 33146\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180418
DTEND;VALUE=DATE:20180520
DTSTAMP:20260821T163919
CREATED:20180418T101107Z
LAST-MODIFIED:20180418T101107Z
UID:19881-1524009600-1526774399@ces.b2sg.org
SUMMARY:Research Technician I
DESCRIPTION:We are seeking a research technician to join a cutting-edge cancer epigenetics laboratory at Massachusetts General Hospital. The position is intended to provide experimental support for projects related to the organization of the cancer genome and its influence on radio- and chemo-therapeutic response\, as well as shared lab management responsibilities. The lab develops and utilizes cutting-edge tools for the genome-wide analysis of chromatin state in normal and malignant cell populations. Areas of ongoing focus include defining the relationship between nuclear organization (“topology”) and therapeutic response\, as well as utilization of targeted genetic screens to identify of epigenetic factors crucial to therapeutic response. \nPRINCIPAL DUTIES AND RESPONSIBILITIES:  \n\nPrepares basic solutions and performs base-level procedures as assigned (i.e. – pipetting\, cell and tissue culture\, etc.) \nMaintains laboratory notebook \nUnderstands and applies basic scientific techniques \nConducts analysis of results and may begin interpretation of results \nSets up and prepares routine experiments as directed \nPrepares lab reagents\, chemicals\, instruments and equipment \nMay perform independent literature searches \nAssists with organizing materials for publication or presentation \nMaintains and orders supplies \n\nA Research Technician II performs the duties of a Research Technician I (above) and may also:  \n\nExecute protocols of non-routine experiments \nAssist the PI(s) with determining the most suitable methodology \nPerform basic design and modification of protocols \nCalculate\, transcribe and analyze data \nPrepare and present reports \nOrganize and summarize acquired data\, using scientific and statistical techniques. \nOrganize and/or draft material for the preparation of research papers\, manuscripts and other documents for publication and/or presentation. \nParticipate in the design of experiments or field work. \n\nSKILLS/ABILITIES/COMPETENCIES REQUIRED:  \n\nAbility to work independently and as a team member \nGood communication skills \nComputer literacy \nWorking knowledge of clinical research protocols \nAbility to perform multiple tasks independently \n\nThe Research Technician II should also possess:  \n\nAnalytical skills and the ability to resolve technical problems \nAbility to interpret acceptability of data results \nWorking knowledge of data management programs \nDemonstrated competence in research techniques and methodologies \n\n\nQualifications \n\nEDUCATION:  \n\nBachelor’s degree required. \n\nEXPERIENCE:  \n\nNew graduates with some lab experience (via course work\, internships\, etc.) or those without any prior research experience will be considered for the Research Technician I position outlined above. \nThose with a minimum of 1 year of directly related work experience will be considered for a Research Technician II position. \n\nSUPERVISORY RESPONSIBILITY (if applicable):  \n\nA Research Technician II may serve as a team leader to lab assistants and Research Technician I’s.
URL:https://ces.b2sg.org/event/mgh-18apr18/
LOCATION:Massachusetts General Hospital Cancer Cente\, 55 Fruit St\, Boston\, MA\, 02114\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180418
DTEND;VALUE=DATE:20180520
DTSTAMP:20260821T163919
CREATED:20180418T103209Z
LAST-MODIFIED:20180418T104216Z
UID:19883-1524009600-1526774399@ces.b2sg.org
SUMMARY:Genome Integrity (Faculty Positions)
DESCRIPTION:The Department of Biochemistry and Molecular Pharmacology at the NYU School of Medicine invites applications for tenure track positions in the areas of biochemical and translational studies related to DNA damage repair pathways\, cell cycle control\, and cancer epigenetics. We seek creative and ambitious applicants with exceptional records of achievement to join our department\, which is comprised of an interdisciplinary faculty with expertise in epigenetics\, genome integrity\, protein degradation\, and chromosome biology ( https://med.nyu.edu/biomolpharm/frontpage ). The candidate’s research interests should synergize with the highly collaborative environment within the Department and throughout the NYU research community. Preference will be given to individuals qualifying at the level of Assistant Professor\, but candidates for appointments above the rank of Assistant Professor with current extramural funding and evidence of active contribution to graduate training and medical education will also be considered. Physician scientists are encouraged to apply. \nNew faculty members will be supported with generous start-up packages\, excellent laboratory space\, access to laboratory animal facilities\, and a wide range of state-of-the-art core facilities providing services in genomics\, proteomics\, RNAi\, bioinformatics\, cell imaging\, flow cytometry\, and pathology. Successful candidates are expected to initiate and maintain a vigorous\, independent\, extramurally funded research program\, participate in the NYU School of Medicine graduate programs within the Sackler Institute and be eligible for membership in NIH-supported training programs designed to support pre- and post-doctoral trainees. \nPh.D. and/or M.D.
URL:https://ces.b2sg.org/event/nyusm-18apr18/
LOCATION:NYU School of Medicine\, 550 1st Avenue\, New York\, NY\, 10016\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180420
DTEND;VALUE=DATE:20180522
DTSTAMP:20260821T163919
CREATED:20180420T091713Z
LAST-MODIFIED:20180420T092545Z
UID:19891-1524182400-1526947199@ces.b2sg.org
SUMMARY:Research Specialist
DESCRIPTION:Under general supervision\, performs a variety of defined research and laboratory tests and experiments according to prescribed protocols and assigned schedules. Sets up experiments as prescribed by a principal investigator. May be required to participate in laboratory maintenance activities such as sterilization and cleaning of equipment\, ordering of supplies\, inventory and media preparation. Maintains records\, files and logs of work performed in laboratory notebooks and computer databases. Compiles data and records results of studies for publications\, grants and seminar presentations. Employees in this classification may be required to work with\, take specific precautions against and/or be immunized against potentially hazardous agents. Performs related responsibilities as required by principal investigator. \nMINIMUM QUALIFICATIONS: Bachelor’s degree in a scientific field OR equivalent combination of experience\, education\, and training. DATE CREATED/MODIFIED/REVIEWED: 06/08/06 AMM \n\n\n\n\nADDITONAL DETAILS\n\n\n\nBackground on epigenetics and/or molecular basis of human genetic disease.\nsome background in cancer and neurological disease preferred.\nLaboratory experience in PCR\, RT-PCR and cDNA library. Transformation\, transfection and titration of viral stocks.
URL:https://ces.b2sg.org/event/emory-20apr18/
LOCATION:Emory University\, 201 Dowman Dr\, Atlanta\, GA\, 30322\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180420
DTEND;VALUE=DATE:20180522
DTSTAMP:20260821T163919
CREATED:20180420T101957Z
LAST-MODIFIED:20180420T102038Z
UID:19899-1524182400-1526947199@ces.b2sg.org
SUMMARY:Postdoctoral Fellowship
DESCRIPTION:Position Summary and Key Responsibilities:\nPositions of two postdoctoral scientistsare open now in the Chen laboratory ( https://www.cityofhope.org/faculty/jianjun-chen ). Our group is interested in discovering novel genetic and epigenetic regulations and deciphering their underlying molecular mechanisms in normal developmental processes (e.g.\, hematopoiesis) and tumorigenesis (e.g.\, leukemogenesis). We cover research areas with relevance to Hematology\, Immunology\, and Cancer Biology\, with an emphasis on RNA epigenetics (mainly focusing on the N 6 methyladenosine (m 6 A) modification) and DNA epigenetics (mainly focusing on the TET1/2/3-mediated DNA demethylation) associated basic and translational research. Our research involves experiments with primary human cancer cells\, cancer and stem cell transplantation models\, mouse genetics\, classic molecular\, biochemistry and cell biology\, functional genomics\, signal transduction\, and large-scale data analysis and computational biology.  \nMinimum Education and Skills Required for Consideration:\nThe candidates for the Postdoctoral scientist positions should have a Ph.D. and/or M.D. degree(s)\, and a solid background in biochemistry\, mouse model studies\, hematology\, epigenetics\, immunology\, pathology\, and/or stem cell research is preferred for. The candidates should not have more than three years of postdoc training experience. The candidates should be highly motivated individuals with the ability to work in a team environment and with good oral and written communication skills in English.  \nApplication:\nPlease apply to this job posting. Additionally\, your application\, including CV\, brief motivation statement\, and contact information of three scientific mentors (references)\, should be saved as a single PDF. The PDF file can be sent to Dr. Jianjun Chen ( jianchen@coh.org ) directly. 
URL:https://ces.b2sg.org/event/hope-20apr18/
LOCATION:City of Hope\, 1500 East Duarte Road\, Duarte\, 91010\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180420
DTEND;VALUE=DATE:20180522
DTSTAMP:20260821T163919
CREATED:20180420T102949Z
LAST-MODIFIED:20180420T102949Z
UID:19902-1524182400-1526947199@ces.b2sg.org
SUMMARY:Director - Sequencing Research
DESCRIPTION:We seek a talented\, collaborative inter-disciplinary scientist to lead innovative application of next-generation sequencing (NGS) methods in close collaboration with Celgene colleagues and strategic research & development partners. \nThis individual will play a key scientific role in the development of internal sequencing resources and the optimization of Celgene NGS assays with focus on novel protocols to elucidate disease and therapeutic mechanisms during the early stages of drug discovery. \nThe role presents an exciting opportunity to build a scientific team that partners and collaborates with laboratory and analytical research colleagues to drive new experimental and data capture strategies\, alongside assessment and selection of external NGS groups to procure well-established assays at scale. \nKey collaborators and stakeholders include researchers in our thematic centers of excellence (TCoEs) and colleagues in the Research Informatics and Knowledge Utilization (RIKU) department\, engaged in work towards key objectives for Celgene Research and Early Development (R&ED). Scientific focus is on development of novel therapies for patients with diseases of unmet need in cancer\, autoimmune and neurological indications. \nAs part of the RIKU organization\, an additional component of the role will be to partner with bioinformatics and data science colleagues to align data generation with computational infrastructure\, and novel experimental methods with innovative analysis and data integration strategies that enable full leverage of NGS output towards research across the R&ED organization and beyond. \nThe position would suit an individual with demonstrated scientific leadership experience and excellent communication and collaboration skills. Keen interest in inter-disciplinary application of high-throughput molecular profiling methods to life sciences data is imperative. Applications are encouraged from those looking to impact delivery of truly innovative and life-changing therapies for complex diseases of unmet medical need. \nResponsibilities include but are not limited to: \n\nLead development of novel NGS approaches\, experiments and protocols aligned to key scientific research objectives\, including adoption of cutting-edge methods from the field.\nWork alongside laboratory and analytical scientists to map NGS approaches to investigational hypotheses and optimize experimental designs.\nAdvise on sample extraction\, library preparation and QC\, and guide collection of supporting metadata across Celgene research groups.\nAssess and select new technologies and external NGS vendors to procure well-established assays at scale\, including design and execution of pilot studies.\nManage the operation of internal next-generation sequencing resources.\nSupervise staff dedicated to NGS core activities and collaboratively develop supporting infrastructures\, including LIMS.\nPresent strategies\, approaches\, results and conclusions to Celgene colleagues and external audiences.\nContribute to enable strategic collaborations with academic and commercial collaborators to benefit therapeutic programs.\n\nQualifications \n\nPh.D. in Biochemistry\, Biology or related field from a recognized higher-education establishment with at least 16 years of relevant work experience\, required.\n10+ years research experience of NGS-focused molecular/chemical biology in university\, hospital or biotechnology environment\nWide-ranging experience in application of NGS platforms to complex biological research questions\, particularly in the areas of cancer and immune biology required.\n\n\nExpertise in the design and procurement of molecular profiling data using contemporary platforms for genomic\, transcriptional and epigenetic profiling and including single-cell profiling techniques required.\nProven ability to lead core activities\, supervise research staff\, and collaborate successfully with laboratory and analytical research groups required.\nBackground in development of novel NGS protocols that enable investigation of scientific hypotheses and elucidation of biological mechanisms required.\nEngagement with and assessment of external technology providers\, including design of pilot experiments\, to guide and inform selection required.\nIn-depth knowledge of contemporary NGS technologies and experimental design considerations\, including assessment of 3rd party capabilities.\nExcellent verbal and written communication skills. Fluent verbal and written English language skills prerequisite.\n\nBackground experience & complementary knowledge: \n\nPublication track-record in use of NGS methods to answer complex research questions in cancer biology\, autoimmune disease and/or epigenetics preferable.\nProven experience in development and application of novel NGS protocols that enable investigation of research hypotheses.\nHands-on experience of sample and library preparation\, operation and maintenance of high- and low-throughput NGS apparatus (Illumina preferable).\nExpertise in standard molecular and cell biology techniques including (at least) real-time PCR\, WGS\, WGBS\, ChIP-seq\, ATAC-seq\, mRNA-seq\, total RNA-seq\, and single cell RNA-seq.\nPrevious experience of staff supervision and operations management in a progressive core NGS facility preferable.\nAwareness of contemporary LIMS schema\, open-source bioinformatics tools and database structures.\nProven problem-solving skills\, collaborative nature and adaptability across disciplines.
URL:https://ces.b2sg.org/event/celgene-20apr18/
LOCATION:Celgene\, 86 Morris Ave\, Summit\, NJ\, 07901\, United States
CATEGORIES:Jobs
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