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PRODID:-//Cancer Epigenetics Society - ECPv5.3.2.1//NONSGML v1.0//EN
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METHOD:PUBLISH
X-WR-CALNAME:Cancer Epigenetics Society
X-ORIGINAL-URL:https://ces.b2sg.org
X-WR-CALDESC:Events for Cancer Epigenetics Society
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TZID:Europe/Paris
BEGIN:DAYLIGHT
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:CEST
DTSTART:20180325T010000
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TZOFFSETFROM:+0200
TZOFFSETTO:+0100
TZNAME:CET
DTSTART:20181028T010000
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180428
DTEND;VALUE=DATE:20180908
DTSTAMP:20260824T001004
CREATED:20180428T131558Z
LAST-MODIFIED:20180428T131558Z
UID:19962-1524873600-1536364799@ces.b2sg.org
SUMMARY:Postdoc Research Associate
DESCRIPTION:This position will employ a wide range of experimental systems and interdisciplinary approaches and provide broad training in 3 areas: a.) control of cell cycle and tumor suppression by the ubiquitin pathway\, b.) tumor metabolism\, and c.) epigenetic control during tumorigenesis and innate immunity with an emphasis on the regulation of DNA de/methylation. The incumbent will be employed to carry out advanced independent and/or directed research to achieve the objectives of the research project. The principal investigator will establish the professional objectives and performance standards for the incumbent and will make annual evaluations. \n\n\n\n\nMinimum Qualifications: \nThis position requires knowledge of the fields\, processes and disciplines of cell biology and cancer metabolism. The position will involve organizing and implementing research plans\, the development of methods of research\, testing and data collection\, analysis and evaluation\, and writing reports containing descriptive\, analytical and evaluative content. The duties require discretion and judgement in carrying out research activities within the predetermined research scope and methodology. A PhD degree in the appropriate biomedical science or related field or discipline\, or the recognized terminal degree\, is required.
URL:https://ces.b2sg.org/event/unc-28apr18/
LOCATION:University of North Carolina – UNC-Chapel Hill\, Chapel Hill\, NC\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180518
DTEND;VALUE=DATE:20180620
DTSTAMP:20260824T001004
CREATED:20180518T090019Z
LAST-MODIFIED:20180522T120337Z
UID:20099-1526601600-1529452799@ces.b2sg.org
SUMMARY:Principal Scientist - Cancer Epigenetics
DESCRIPTION:Pfizer Oncology Research & Development (ORD) in La Jolla\, California\, is seeking a Principal Scientist focused on translating basic discoveries in the field of cancer epigenetics into novel therapeutics. \nOur ideal candidate will lead a team of motivated and scientifically rigorous scientists to perform laboratory-based research in a collaborative team environment. The candidate will lead biological target validation\, utilizing genetic and pharmacological approaches to discover and confirm candidates for novel cancer therapeutics. As a member of the group\, you will also be involved in mechanism-of-action studies\, interpretation and presentation of data\, and will function as an integral member of the team to advance new targets. The successful candidate will have experience in the integration of molecular profiling data including epigenomic (ATAC-seq\, ChIP-seq)\, transcriptomic\, proteomic\, and genomic datasets\, into a broader understanding of epigenetic regulation within the tumor and interactions between the tumor and the tumor microenvironment. \nRole Responsibilities \n\nLead a laboratory research group to study genetic and epigenetic mechanisms in tumor biology with the aim to identify new therapeutic targets that can be translated to the clinic\nUtilize expertise in epigenetic biology to design\, execute\, and analyze/interpret innovative approaches for epigenetic targeting in cancer.\nWork collaboratively with computational biology group to integrate complex data sets including epigenomic and other ‘omic’ data in pre-clinical settings for target discovery\, validation\, and advance mechanism of action target biology\nLead development of cell and molecular assays to define mechanism of action\, measure pharmacodynamic changes and select responder patient populations.\nInterface with discovery biology and computational biology groups to design\, develop\, and interpret datasets developed from genetic and pharmacological screens\nDevelop and apply complex in vitro assays including organoids to enable target discovery\, validation and drug development.\nProactively seek out new information in the literature and incorporate this into individual project(s) as well as the overall program.\nPresent research results and methodologies at weekly meetings with immediate supervisor and/or project leader\, and at meetings with members of the oncology research unit as appropriate.\nContribute to building a culture that embraces scientific excellence\, urgency\, partnerships with key stakeholders\, continuous learning and improvement\, increasing technical skill base and cancer biology expertise; take a proactive role in personal growth and scientific development.\n\nBasic Qualifications \n\nPhD in Molecular Biology\, Pharmacology (or a comparable biological science) plus post doc and 4+ years of relevant experience in an academic or pharmaceutical/biotech environment.\nExpertise in chromatin biology\, epigenetics and mechanism of transcriptional regulation as evidenced by publication in peer-reviewed journals.\nExtensive knowledge and experience in areas of tumor biology including\, but not limited to immune oncology\, oncogenic signaling\, cancer metabolism\, apoptosis and/or DNA damage and repair\nDemonstrate proficiency in the use of software tools to support epigenomic data analysis including ATAC-seq\, ChIP-seq\, and RNA-seq.\nExperience in use of CRISPR-based techniques for gene knockout\, gene editing and as well as working knowledge of pooled CRISPR -based screening approaches\nAble to work in a team environment\, good communication skills and excellent leaderships skills.\nExperience managing scientists\n\nPreferred Qualifications \n\nPreference for candidates with a strong track record in cancer drug discovery and the targeting of epigenetic pathways by small-molecule inhibitors.
URL:https://ces.b2sg.org/event/pfizer-18may18/
LOCATION:Pfizer – Pearl River\, NY\, 401 North Middletown Road\, Pearl River\, NY\, 10965\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180519
DTEND;VALUE=DATE:20180715
DTSTAMP:20260824T001004
CREATED:20180519T171048Z
LAST-MODIFIED:20180519T171231Z
UID:20115-1526688000-1531612799@ces.b2sg.org
SUMMARY:Postdoctoral Associate
DESCRIPTION:An exciting opportunity is available to join a cancer pharmacology lab that emphasizes pharmacokinetic (PK)\, pharmacodynamic (PD)\, and quantitative systems pharmacology (QSP) approaches to study brain tumors. The lab integrates experimental data with mathematical models or QSP models to characterize drug action and predict drug responses in patients. The ultimate goal is to bridge preclinical and clinical drug development paradigms and advance precision medicine. \nThe postdoctoral position is in the lab of James M. Gallo in the Department of Pharmaceutical Sciences\, School of Pharmacy and Pharmaceutical Sciences at the University at Buffalo. The department is a premier research unit with a storied tradition of excellence in PK/PD research. Ongoing projects are in anticancer drug development\, drug resistance\, cell state\, epigenetics and tumor heterogeneity. \nThe postdoctoral associate will join a highly interactive department with a central focus of PK/PD/QSP modeling\, and have opportunities to interact with highly talented graduate students\, and scientists within the university including Roswell Park Cancer Institute. Position responsibilities include: \n\nDevelop PK/PD/QSP models using a variety of computer programs.\nParticipate in lab meetings and contribute to the training of students and lab personnel in advanced modeling methods.\nInteract positively with scientific personnel across different disciplines to advance QSP.\nProvide expert support of computer systems used for the labs modeling efforts.\nMaintain abreast of current literature in the fields relevant to lab projects.\nProvide reports based on your work for scientific publications and extramural funding applications.\nAdvance your knowledge of QSP modeling methods and implement those as needed\n\n\n\n\nMinimum Qualifications\n\n\nPh.D. in Engineering\, Mathematics\, Pharmacometrics\, Systems Biology/Pharmacology or a related field.\nDemonstration of mathematical modeling & computer simulation experience; preferably related to biomedical/pharmaceutical applications.\nExpertise in Matlab/SimBiology/Simulink.\nAdditional familiarity with R\, JDesigner/Systems Biology Workbench and related programs desirable.
URL:https://ces.b2sg.org/event/buffalo-19may18/
LOCATION:University at Buffalo\, Buffalo\, NY\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180520
DTEND;VALUE=DATE:20180622
DTSTAMP:20260824T001004
CREATED:20180520T133216Z
LAST-MODIFIED:20180520T133216Z
UID:20129-1526774400-1529625599@ces.b2sg.org
SUMMARY:Research Associate- General Surgery
DESCRIPTION:Job Summary/Essential Job Functions:  Under the direction of the Principal Investigator\, the Research Associate will work independently and perform assigned research.  This position requires strong knowledge of biomedical science\, processing of samples for cellular studies\, including cell sorting\, immunophenotyping\, cell culture\, establishing and keeping mice models for validation of identified pathway\, among other laboratory techniques.  This position will also manage\, designs and carries out experiments\, analyzes\, interprets and present data analyses and interpretation \n  \nDUTIES AND RESPONSIBILITIES:\n \n\nPreparation of samples for cellular studies\, data analyses\, and interpretation.\nPerform cellular/immunological study design.\nPerforms research experiments focused on understanding the role of Id3 in local B cell immune responses before and during liver ischemia reperfusion injury and disease development.\nPerforms Epigenetics ischemia reperfusion injury experimental procedures.\nPerforms experiments related to liver donor quality and mechanistic studies in liver cancer.\n Studies mechanistic chronic kidney disease.\nResearches and develops strategies to minimize ischemia reperfusion injury and pump perfusion.\nMaintain liver biorepository collections of samples.\nDocument experimental processes and results for preparation of scientific reports.\nWorks in conjunction with the PI in preparation of manuscripts\, grants and research compliance documents.\nSubmits published papers and obtain grant funding.\nPerform other duties as required.  \n\n \n \n  \nJOB SPECIFICATIONS:\n\nPh.D. Biological Science; four (4) years cell biology\, molecular biology\, biochemistry techniques; including cell culture\, molecular biology techniques.  The ability to prioritize and coordinate activities of the lab. Laboratory experience\, ability to maintain confidentiality and make sound independent judgments\, excellent verbal/written communication and leadership skills.  Working knowledge of databases\, spreadsheets\, word processing and other special programs for data analysis.  
URL:https://ces.b2sg.org/event/utnhsc-20may18/
LOCATION:University of Tennessee Health Science Center\, Memphis\, TN\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180520
DTEND;VALUE=DATE:20180622
DTSTAMP:20260824T001004
CREATED:20180520T141606Z
LAST-MODIFIED:20180520T141606Z
UID:20133-1526774400-1529625599@ces.b2sg.org
SUMMARY:Postdoctoral Research Fellow
DESCRIPTION:The Thyroid Cancer Research Laboratory at MGH studies key genetic and epigenetic changes in those thyroid cancer patients who do poorly. We are seeking an experienced research fellow interested in pursuing innovative studies on pre-clinical mouse models of thyroid cancer and has an established interest and skillset that includes tumor immunology\, an understanding of mouse models of malignancy and a basic understanding of bio-informatics. \n\nPrincipal Duties & Responsibilities: The Research Fellow will join a collaborative group of scientists with expertise in studying the basic and translational biology of thyroid cancer. The research aims are to characterize the genetic changes in thyroid cancer that leads to proliferative\, immune and stromal alterations. This position provides outstanding opportunities for continued scientific development and for contributing to pioneering research with high translational impact. The scientific environment at MGH and surrounding institutions offers ample opportunity for productive collaborations. \n  \nJob Requirements: The candidate will have a solid foundation in experimental research with a strong record of publication. A PhD or MD/PhD degree is required. Expertise in molecular and immune cell biology is necessary. Experience working with rodents and immune assays as well the ability to work independently is preferred. Fundamental knowledge of signaling pathways\, tumor immunology and bioinformatics is important. Outstanding oral and written communication skills are important as well as willingness to work with collaborators and train students and residents. Those with a history of successful grant writing experience will be given preference. \n\nAdditional Information: Please include a cover letter with your resume which details your interests in thyroid cancer and 2-3 names of people who could immediately provide letters of reference. \n\nTo apply for this position\, please email or send your resume to: \nSareh Parangi\, MD \nProfessor of Surgery\, Harvard Medical School \n15 Parkman Street\, Wang 460\, Boston\, MA 02114 \nsparangi@mgh.harvard.edu
URL:https://ces.b2sg.org/event/mgh-20may18/
LOCATION:Massachusetts General Hospital Cancer Cente\, 55 Fruit St\, Boston\, MA\, 02114\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180520
DTEND;VALUE=DATE:20180622
DTSTAMP:20260824T001004
CREATED:20180520T172022Z
LAST-MODIFIED:20180520T172022Z
UID:20139-1526774400-1529625599@ces.b2sg.org
SUMMARY:Postdoc Research Fellow - Oncogenesis
DESCRIPTION:The Hackensack Meridian Health Center for Discovery and Innovation is offering a position for postdoctoral studies in the field of cancer signaling and gene expression in the laboratory of Dr. Byungwoo Ryu. The goal of the laboratory’s research program is to unravel the cancer epigenome regulating mechanisms which can be targeted for the sensitization to the precision therapies in the hope of translating these therapeutic modalities to have long-term clinical benefit. The Ryu laboratory focuses on investigating chromatin remodeling enzymes\, such as histone and DNA modifiers and gene transcription factors as potential targets for overcoming the resistance of oncogene-targeting therapies and enhancing the objective therapy response rate of immune check-point blockade therapies. The Ryu laboratory uses chemical genetics approaches including small molecule inhibitors\, genome/epigenome-wide profiling\, gene-editing technology\, and animal models. Successful postdoctoral candidate will have a strong interest in cancer biology\, epigenetics\, and immuno-oncology. The candidate will perform in vivo animal models and in vitro analyses. The postdoctoral fellow is expected to understand the project and work independently taking responsibilities in the development and execution of experimental procedures to successfully advance the research project. The successful candidate will be responsible for preparing data for presentations\, progress reports\, and the preparation of manuscripts and posters. The post-doctoral fellow is anticipated to have good communication and writing skills. The successful candidate will have a team-oriented mindset and will provide guidance to junior members. \n\n\n\nResponsibilities\n\n\n\n1. Proficient at most gold standard assays in molecular biology and genetics. 2. Design and conduct animal studies using a vast array of genetic models. 3. Perform data analysis and interpretation. 4. Present results in internal and external research forums. 5. Participate in grant and manuscript writing\, as appropriate. \n\n\n\nQualifications\n\n\n\nEducation\, Knowledge\, Skills and Abilities Required: 1. Hold a Ph.D. in Molecular Biology\, Biochemistry\, Cancer biology or equivalent from an accredited graduate level institution. 2. Minimum publication or in preparation of one article as first author in a reputable peer-reviewed scientific journal. 3. Excellent analytical and presentation skills. 4. Expertise in cell culture\, flow cytometry\, mouse handling\, and basic cellular and molecular biology techniques required. Education\, Knowledge\, Skills and Abilities Preferred: 1. Knowledge and experience with RNA/DNA extraction\, PCR and qPCR analysis\, and next generation sequencing/bioinformatics a plus. 
URL:https://ces.b2sg.org/event/hackensack-20may18/
LOCATION:Hackensack Meridian Health\, Hackensack\, NJ\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180521
DTEND;VALUE=DATE:20180623
DTSTAMP:20260824T001004
CREATED:20180521T065023Z
LAST-MODIFIED:20180521T065830Z
UID:20145-1526860800-1529711999@ces.b2sg.org
SUMMARY:Senior Scientist-In Vivo Pharmacology Oncology
DESCRIPTION:We seek an accomplished Senior Scientist level oncologist/immunologist to join the in vivo pharmacology group within the Oncology Research Unit (ORU) of Pfizer’s Worldwide Research & Development (WRD) division in La Jolla\, California. The successful candidate will join a dynamic team of scientists in the Oncology In Vivo Pharmacology Group\, playing a leading role in the characterization of models of cancer and evaluating new drug candidates. \nParticipate in pre-clinical drug discovery and development projects with a focus on targeted therapeutics\, epigenetics and the tumor microenvironment. Characterize and develop small molecules in close collaboration with partner lines as an integral member of drug discovery teams. Evaluate anti-tumor effects in combination with biologics. Employ and develop new cutting-edge in vivo mouse and human cancer models. Provide technical and scientific expertise in in vivo pharmacology to the tumor cell biology department to enable target identification\, validation\, prioritization and efficient drug discovery of small molecules. \nThe candidate must have a strong background in immunology with extensive hands-on experience in multi-parameter flow cytometry analysis of tumor infiltrating immune cells (Fortessa-X20\, Cytobank\, FlowJo\, FACS\, MACS). \nIdeal applicants will have excellent communication\, leadership and organizational skills\, critical problem-solving abilities\, and a commitment to excellence.  \nROLE RESPONSIBILITIES \n\nPlan\, execute and analyze multi-parameter flow cytometric analysis studies of cells within the tumor microenvironment.\nResponsible for building and continuously updating flow panels based on recent scientific advances. Maintenance and upgrade of equipment (Fortessa-X20).\nDevelop and characterize new in vivo mouse models\, including syngeneic tumor and genetically engineered mouse (GEM) models\, to study biologic mechanisms and support exploration of novel therapies.\nDesign and conduct in vivo studies to evaluate and establish efficacy\, PK/PD relationship\, combination strategy\, biomarker identification and analysis.\nInterpretation\, presentation and documentation of experiments as well as preparation of reports.\nWritten and verbal presentation of results within a multidisciplinary team environment.\nPublication of results in scientific peer-reviewed journals and presentations at internal\, national\, and international meetings.\nMay manage a colleague\n\nBASIC QUALIFICATIONS \n\nPh.D. (or M.S. degree with 7+ years’\, or B.S. degree with 10+ years’\, relevant post-graduate experience) in Cancer Biology\, Immunology or related discipline.\nExtensive expertise in multi-parameter flow cytometry analysis of tumor infiltrating immune cells (Fortessa-X20\, Cytobank\, FlowJo\, FACS\, MACS).\nExpertise in in vivo pharmacology and experience with animal models of human cancers as well as strong publication record or evidence of equivalent achievements in industry are desired.\nHands on in vivo skills (IV\, PO dosing)\, blood/tissue collection\nProven ability to make important contributions to cancer biology\, immuno-oncology or related fields\nAbility to follow novel scientific or technological developments\, and to implement them in the laboratory.\nCurrent knowledge of oncology research\, drug discovery and development.\nExcellent written and oral communication and presentation skills in English.\nStrong ability to multi-task and work productively in a fast-paced\, highly collaborative\, and diverse team environment. Capability to contribute to a vivid and challenging intellectual environment.
URL:https://ces.b2sg.org/event/pfizer-21may18/
LOCATION:Pfizer – La Jolla\, CA\, 10350 N Torrey Pines Rd\, La Jolla\, CA\, 92037\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180521
DTEND;VALUE=DATE:20180623
DTSTAMP:20260824T001004
CREATED:20180521T070643Z
LAST-MODIFIED:20180521T070753Z
UID:20149-1526860800-1529711999@ces.b2sg.org
SUMMARY:Computational Biologist
DESCRIPTION:Dr. Tim Triche Jr. is seeking a full-time Computational Biologist to join his research team. The Triche Lab focuses on developing statistical and mathematical methods to dissect pediatric and adult cancers\, with a focus on cancers of the blood in children. In pediatric tumors\, recurrent mutations alone are rarely sufficient to characterize a person’s disease\, and the role of inherited susceptibility is poorly understood. The lab seeks to improve both outcomes and quality of life by rational selection of positive (“Patients with X usually respond to A”) biomarkers for response and negative (“Patients with Y rarely respond to B”) biological markers for non-response over the course of disease. Particularly in rare tumors\, this approach is well suited to rapidly piloting clinical trials and re-purposing existing drugs; indeed\, one such regional DNA methylation marker is currently in a Phase III trial for front-line chemotherapy. \nWe collaborate broadly with clinical and basic scientists. The role of chromatin- and DNA-modifying proteins\, under the catchall term epigenetic regulators\, is a primary interest. Recent work characterizing genetic influences on transcription suggests that rare variants dominate the landscape\, motivating an alternate readout of regulatory aberrations. We are developing methods to improve both variant prioritization and interpretation of regulatory impacts by jointly analyzing both. To do so\, we make heavy use of high-throughput sequence analysis\, both in bulk and sorted cells\, often from clinical trials. \nOurs is a young lab. You will help determine its growth and direction\, and it will help determine yours. \nIn this role\, you will be responsible for the following tasks: \n\nHandle data management and reproducible analysis for a variety of experimental designs\nDevelop\, maintain\, and support computational biology pipelines\nPerform data mining at scale on both local and (where feasible) cloud pilot resources\nPre-print and publish results and novel methods\, serving as primary or contributing author\, while ensuring compliance with data sharing plans\, and wherever possible\, unsupervised replication\nAnticipate and keep abreast of new developments in bioinformatics and works to ensure the availability of state-of-the-art methods\, resources\, and data sources to support the user groups\nPerform other related duties as assigned (to include wet protocols if suited to the candidate)\n\n\nThis list will likely change as projects evolve and you must be open-minded to learn new things. \nExpectations: \nThe following expectations should be met within the first 3 months. \n\n1 month – Develop solid understanding of at least one major collaborative project\, adapt to VAI computing resources\, and demonstrate analytical reproducibility\, supervised by a senior collaborator\n3 months – Acquire significant data\, prepare informative summaries of interim analyses\, and take over both maintenance and development of analytical pipelines from our senior collaborators.\n\n\nQualifications: \nYou will possess a Master’s degree in computational biology\, bioinformatics\, mathematics\, statistics\, computer science\, or other relevant discipline (a BS with experience will be considered). \nThe ideal candidate \n\nHas working knowledge of at least one scripting language (e.g. R) and systems language (e.g. C)\nHas substantial experience with the analysis of next generation sequencing data (e.g. RNAseq)\nHas experience\, or interest in gaining experience\, with data integration (e.g. ATAC\, WGBS\, Hi-C)\nHas an understanding of cancer biology or genetics; this is helpful but not absolutely required.\nMay see this position as an ideal launching point for further graduate or clinical studies.\nHas a commitment to open\, collegial\, reproducible science\, and the betterment of society.\n\n\nIf you possess these attributes and desire to help us drive science from the bench to the clinic\, while benefiting from a highly generous compensation package; we would welcome speaking with you and encourage you to apply today.
URL:https://ces.b2sg.org/event/vari-21may18/
LOCATION:Van Adel Research Institute\, Grand Rapids\, MI\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180522
DTEND;VALUE=DATE:20180624
DTSTAMP:20260824T001005
CREATED:20180522T110717Z
LAST-MODIFIED:20180522T110717Z
UID:20209-1526947200-1529798399@ces.b2sg.org
SUMMARY:Research Fellow
DESCRIPTION:A Research Fellow position is available in the program of Dr. Keith Robertson. For more information about Dr. Robertson’s program\, please see: http://www.mayo.edu/research/faculty/robertson-keith-d-ph-d/bio-20035097 \nThe successful candidate will join the Epigenetic Etiology of Human Disease Laboratory to study the role of DNA epigenetic modifications in human disease. More specifically\, he/she will examine how DNA methylating and hydroxymethylating enzymes regulate their respective DNA epigenetic modifications and how these marks modulate expression and genome stability\, and interface with other epigenetic modifications. Disease focus areas of the laboratory include cancer (hepatocellular and renal)\, obesity\, and diabetes. Specific research areas include application of genome-wide epigenomics methods to decipher DNA methylation/hydroxymethylation defects in cancer and biochemical/cell culture-based techniques to study the regulation and interactions between chromatin remodeling factors (e.g. DNMTs\, TETs\, HMTases) and the roles of their target loci in driving disease. Techniques commonly used in the laboratory include: quantitative RT-PCR\, western blotting\, cell culture\, transfections\, bisulfite sequencing\, DNA immunoprecipitation\, pyrosequencing\, ChIP-qPCR\, ChIP-seq\, next-gen library preparation and sequencing\, Infinium 850k arrays\, bioinformatics analysis\, microscopy\, and biochemical analysis of protein function. Experience in one or more of these areas is a plus. The candidate will play a major role in the preparation of manuscripts that arise from this work and devote 100% effort to these tasks (no patient contact or other responsibilities). \nPosition description \nA Research Fellow at Mayo Clinic is a temporary position intended to provide training and education in research. Individuals will train in the research program of a Mayo Clinic principal investigator. Qualified individuals will demonstrate the potential for research as evidenced by their training and peer-reviewed publications and should become competitive for national research grants. Proof of English proficiency is required for J-1 Short-Term Scholars\, Research Scholars\, Professors\, Specialists\, and Student Interns sponsored by Mayo Clinic. 800146; J2WRTP \nQualifications \nMust have a Ph.D.\, M.D.\, or equivalent doctoral degree in a field deemed relevant by the program. Research Fellow is appropriate for individuals who have completed no more than one prior postdoctoral fellowship\, at Mayo Clinic or elsewhere.
URL:https://ces.b2sg.org/event/mayo-22may18/
LOCATION:Mayo Clinic\, 200 1st St SW\, Rochester\, MN\, 55905\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180522
DTEND;VALUE=DATE:20180624
DTSTAMP:20260824T001005
CREATED:20180522T111743Z
LAST-MODIFIED:20180522T112043Z
UID:20211-1526947200-1529798399@ces.b2sg.org
SUMMARY:ASSOCIATE SCIENTIST - CANCER IMMUNOLOGY
DESCRIPTION:Neon Therapeutics is an immuno-oncology company focused on developing novel therapeutics leveraging neoantigen biology to treat cancer. Neon utilizes its expertise in bioinformatics\, neoepitope prediction and immune monitoring to identify tumor specific mutations and monitor clinical response to their personalized vaccines. Neon Therapeutics’ lead program is NEO-PV-01\, a bespoke neoantigen vaccine that builds upon years of research and development at the Broad Institute and Dana-Farber Cancer Institute. NEO-PV-01 is now being studied in a Phase 1b clinical trial combining the vaccine with Opdivo®\, a PD-1 immune checkpoint inhibitor from Bristol-Myers Squibb\, in patients with measurable metastatic melanoma\, non-small cell lung cancer and bladder cancer. Three additional clinical trials are planned for 2018. Also in development are NEO-PTC-01\, a bespoke autologous T cell therapy\, and NEON / SELECT\, a Shared Neoantigen Program leveraging neoepitopes that are common across patients and tumor types.\nIn addition\, Neon has established strategic partners in BMS\, Merck\, and Apexigen to harness opportunities for combination therapies. Neon leverages foundational intellectual property from the Broad Institute and the Dana-Farber Cancer Institute.Neon Therapeutics was incubated and launched by Third Rock Ventures and raised a $55M Series A in 2015 and\, more recently\, a $106M Series B in 2017. \n\nPosition Summary \nThe successful candidate will work in the Neon SELECT program that aims to develop therapies against neoantigen targets shared across patients. S/he will focus on generating and studying T cell responses to shared neoantigens\, with particular focus on peptide design and T cell receptor characterization. The candidate will need to work on a team but also independently test many different technologies. S/he will need to work effectively on a team while also independently perform cell and molecular biology assays. The candidate will work closely with the departments of T cell immunology\, molecular immunology\, peptide chemistry\, and bioinformatics. \nJob Responsibilities: \n\nCulture and manipulation of human T cells\nAssessment and analysis of specificity of human T cells by multicolor flow cytometry\nPerform scRNA and TCR sequencing as well as data analysis\nDesign and analysis of immunogenic peptide sequences\nProduction of stable cell lines using transfection or transduction\nAnalysis and presentation of results to larger scientific groups\nAssist with the training of lab personnel\nWork productively in a team environment and independently and deliver against timelines.\n\nExperience and essential skills: \n\nM.S. with 5-8 years of experience\, or Ph.D. with 0-2 years of experience in industry with a strong background in immunology.\nA strong background in adaptive immunity in the context of cancer is preferred\nDemonstrated mastery of flow cytometry and related data analysis\nExperience with functional immune assays\, such as cytokine analysis\nGeneral molecular biology techniques\, including plasmid cloning and preparation\nExperience with lentivirus preparation and infection\nAbility to organize and tabulate data.\nStrong evidence of leadership background and experience working in cross-functional teams\nExcellent and record-keeping skills.\nStrong written and oral communication skills.\nIndependent\, flexible\, self-motivated.\n\n\nTo apply\, please send your resume to careers@neontherapeutics.com
URL:https://ces.b2sg.org/event/neon-22may18/
LOCATION:Neon Therapeutics\, 40 Erie St\, Cambridge\, MA\, 02139\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180523
DTEND;VALUE=DATE:20180625
DTSTAMP:20260824T001005
CREATED:20180523T160122Z
LAST-MODIFIED:20180523T160122Z
UID:20231-1527033600-1529884799@ces.b2sg.org
SUMMARY:Postdoctoral Research Fellow
DESCRIPTION:Receive training in specific area(s) of research with the aim of progressing towards an independent career. The appointment is for one year up to a usual maximum of three to four years\, each year contingent upon satisfactory progress\, as evaluated by the supervisor/mentor. \nKey Responsibilities: \n– Receive training in specific area(s) to continue the development of personal technical knowledge and research expertise.\n– Under guidance\, design\, plan and execute original research projects or major parts thereof.\n– Develop ability to critically evaluate and analyze data.\n– Keep a careful record of experiments in laboratory notebooks.\n– Publish and present data internally and externally.\n– Assist other institute researchers in areas of personal expertise.\n– Attend and participate in institutional programs\, seminars and lectures.\n– Progress towards an independent career.\n– Encouraged to seek outside training support.\n– Provide other related duties as required \nEducation: \n      PhD in relevant field of study \nPlease complete application and submit CV to be considered for this position.
URL:https://ces.b2sg.org/event/buck-23may18/
LOCATION:Buck Institute\, 8001 Redwood Boulevard\, Novato\, CA\, 94945\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180523
DTEND;VALUE=DATE:20180625
DTSTAMP:20260824T001005
CREATED:20180523T161745Z
LAST-MODIFIED:20180523T161759Z
UID:20234-1527033600-1529884799@ces.b2sg.org
SUMMARY:
DESCRIPTION:Education: Ph.D. in molecular biology\, biochemistry\, or related field with preferred dissertation research on human or mammalian epigenetics; alternately\, M.S. plus at least five years of experience in a related field \nYears of experience: Ph.D. – At least one year of postdoctoral research in a demonstrably relevant area; M.S. – at least five years of experience \nRequired Skills: \n\nExtensive experience identifying epigenetic signatures resulting from pathology (such as viral infection or cancer)\nExperience with high-throughput assays for identifying epigenetic modifications (e.g.\, next-gen sequencing\, microarrays\, pyrosequencing\, etc.)\nDemonstrated experience analyzing genome-wide methylation profiling or chromatin remodeling\nKnowledge of virology or other infectious disease models strongly preferred\nStrong oral\, written\, and interpersonal communication skills and abilities;\nDemonstrated time management and completion of tasks to a definite deadline\nBioinformatics experience (e.g.\, experience working in a Linux environment and common scripting languages) is desirable\nCandidates must be willing to submit and be eligible for a DoD secret clearance (i.e.\, must be subject to and pass a background investigation and must be a U.S. citizen).\nMust be able to do extended deskwork at a computer\nMust be able to stand for several hours at a time to perform lab work\nMust be able to wear standard PPE (e.g.\, mask\, gloves\, lab coat) for extended periods of time\n\n\nPrimary Responsibilities: \n\nLead efforts based on the identification of epigenetic biomarkers of exposure to biological and chemical pathogens. Support experimental design\, development and optimization of biomarker identification methods and workflows\, and data analysis to validate prospective markers.\nLead and/or support technical tasks or projects within a collaborative teaming environment. The Epigenetics Specialist will work within a team of molecular biologists\, forensic scientists\, biochemists\, bioinformaticians\, database managers\, statisticians\, and project managers to provide solutions to maximize the utility\, confidence\, and rapid reporting of results for large epigenetic datasets.\nSupport projects through employing efficient and accurate data evaluation techniques\, placing levels of statistical confidence on data output\, and clearly reporting results.\nInteract with clients (on and off-site) and present technical data through presentations and report writing.\nSupport end user trainings and client interactions.\nHelp grow the biological sciences business area through the successful and timely execution of projects\, positive interactions with clients\, recognition of opportunities for follow-on work with existing clients\, establishment of new opportunities with alternate clients\, proposal development and writing support\, and maintaining a presence at marketing and business development meetings/conferences.\nTravel to project and business development meetings as needed.\nReport directly to the biology Business Area Manager under the advisement of the Director of Biological Sciences.
URL:https://ces.b2sg.org/event/signature-23may18/
LOCATION:Signature Science LLC
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180524
DTEND;VALUE=DATE:20180626
DTSTAMP:20260824T001005
CREATED:20180524T145813Z
LAST-MODIFIED:20180524T145927Z
UID:20250-1527120000-1529971199@ces.b2sg.org
SUMMARY:Research Associate
DESCRIPTION:To enable Guardant Health to lead the disruption of cancer treatments through non-invasive cancer screening\, the Technology Development Team is seeking a highly motivated Research Associate to help develop\, test\, and improve sample preparation technologies for rare variant and epigenetic studies with next-generation sequencing. At Guardant\, we leverage the most advanced technologies and work with leaders in many different fields to create the most impactful and meaningful technologies for cancer management. \nAs a Research Associate supporting product and technology development\, you will work with members within the team and interface with multiple teams including process engineering\, clinical operations\, research operations\, and bioinformatics. You will be hands on in the lab and be required to design\, implement\, and validate new technologies related to liquid biopsy sequencing assays for the early detection\, treatment\, and monitoring of all cancer types. \n\nOperate next generation sequencing instruments\nRun sequencing sample preparation assays in medium to high throughput environment\nTest and improve new sequencing sample preparation assays\nLog and track research samples throughout sequencing workflow\nMaintain appropriate inventory of lab supplies\nBring a can-do attitude to solve new and challenging problems in a high pace environment\nAnalyze data and troubleshoot issues within the tech dev team and among other teams\nCollaborate with all functions within project teams\nEngage in early design of products and perform experiments both independently and under the supervision of Senior team members within Tech Dev and Bioinformatics groups\nCan present updates\, write reports and SOPs\, and contribute to technical discussions\n\n\n\nQualifications \n\nThe ability to handle biological samples (i.e. tissue\, bio-fluid\, etc.) is a must\nExcellent written and oral communication skills is a must\nProfessional hands-on experience in industrial setting in genomics field is a plus (operational experience is preferred)\nHands-on experience in running sequencing platforms and assays is a plus
URL:https://ces.b2sg.org/event/guardant-24may18/
LOCATION:Guardant Health\, 505 Penobscot Dr.\, Redwood City\, CA\, 94063\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180524
DTEND;VALUE=DATE:20180626
DTSTAMP:20260824T001005
CREATED:20180524T150953Z
LAST-MODIFIED:20180524T150953Z
UID:20253-1527120000-1529971199@ces.b2sg.org
SUMMARY:Principal Research Scientist
DESCRIPTION:The Principal Research Scientist applies extensive biology and drug development expertise to oversee cross- functional research teams that are tasked with identifying and validating novel oncology targets\, and then apply deep biology insights to then translate these finding to position novel oncology therapeutic agents in contexts that maximally benefit patients.  \nThe mission of The Center for Co-Clinical Trials (CCCT) is to integrate biological insights with drug discovery expertise to accelerate the development of innovative targeted cancer therapeutics. The CCCT is a ground-breaking translational research team that partners with world-class drug discovery scientists at the Institute for Applied Cancer Science (IACS) along with their industry-modelled in vivo pharmacology unit and state-of-the-art computational biology infrastructure. CCCT’s cross- functional teams aim to deliver biological insights regarding genetic and functional contributions that influence tumor response to novel therapeutic agents or regimens. As part of the MD Anderson Cancer Center Moon Shots initiative\, the capabilities of the CCCT\, in concert with IACS\, support the institution’s academic and clinical research programs to help us reach our goal of delivering safer\, more effective treatments to our patients.  \nSalary Range Min $129\,000- Mid $161\,000 – Max $193\,000  \nKEY FUNCTIONS:\n1.Principal Research Scientist applies expert knowledge of tumor biology in areas such as immune oncology\, oncogenic signaling\, metabolism\, epigenetics and/or DNA damage to enable target discovery\, validation and drug development.  \n2.Oversee and/or lead multiple cross- functional research drug discovery and development programs.  \n3.Lead collaborations with computational biologists utilizing patient-centric –omic databases to identify deregulated contexts that inform on target discovery\, target validation and translational biology efforts in defined tumor contexts.  \n4.Oversee the design\, execution\, analysis and interpretation of in vitro\, ex-vivo and in vivo experiments to validate targets\, optimize compound selection and explore therapeutic potential of drug targets.  \n5.Apply knowledge of pharmacology to enable in vivo assessment of chemical matter and establishment of pharmacodynamics\, pharmacokinetic and efficacy relationships.  \n6.Lead drug discovery biology efforts to enable selection of lead candidate molecules.  \n7.Apply expertise to lead the discovery\, validation and development of cell and molecular assays to define mechanism of action\, measure pharmacodynamic changes and select patient responder populations.  \n8.Lead program biology efforts to enable clinical positioning of developmental candidates.  \n9.Develop and lead strong collaborative relationships with internal and external groups.  \n10.Manage activity of direct reports and project teams.  \n11.Interpret\, present and report research findings at internal meetings and external scientific conferences.  \n12.Evidence of independent thinking and leadership skills are vital. Ability to work well under pressure and drive projects that impact critical timelines is essential  \nEducation  \nRequired: PhD in one of the natural sciences or related field or Medical degree.  \nExperience  \nRequired: Seven years experience of relevant research experience in lab.  \nIdeal Candidate will possess the following:\n1.MD or PhD with over 7 years of relevant post-degree experience in a pharmaceutical/biotech environment.  \n2.Evidence of utilization of cancer genomics to inform on target discovery\, validation and/or clinical positioning of development drug candidates.  \n3.Experience with genetic (ie RNAi and cDNAs) and pharmacological (i.e. small molecule inhibitors or antibodies) approaches to study target biology utilizing biochemistry\, cellular and molecular biology methods and assays to drive program biology.  \n4.Experience utilizing mouse models of cancer to enable target discovery\, validation\, drug development and/or translational biology.  \n5.Experience working with chemists\, in vitro and in vivo pharmacologists to develop and utilize assays in support of the development of small molecules for target validation and as part of lead optimization.  \n6.Extensive knowledge and experience in areas of tumor biology including\, but not limited to immune oncology\, oncogenic signaling\, cancer metabolism\, epigenetic deregulation\, apoptosis and/or DNA damage and repair as evidenced by publication in peer-reviewed journals.  \n7.Strong data analysis skills\, ability to interpret results\, design of follow-up experiments\, troubleshoot issues with assay performance\, and effectively present results and conclusions to co-workers\, collaborators and senior leadership.  \n8.Evidence of leading multi-functional teams of scientists to deliver on program objectives.  \n9.Evidence of independent thinking and leadership skills. 
URL:https://ces.b2sg.org/event/mda-24may18/
LOCATION:MD Anderson Cancer Center\, 1515 Holcombe Blvd\, Houston\, TX\, 77030\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180525
DTEND;VALUE=DATE:20180627
DTSTAMP:20260824T001005
CREATED:20180525T084047Z
LAST-MODIFIED:20180525T084059Z
UID:20256-1527206400-1530057599@ces.b2sg.org
SUMMARY:Labratory Technican
DESCRIPTION:The Department of Medicine\, Division of Hematology/Oncology is looking to fill two OPS Lab Tech positions. The selected candidates will need to be highly motivated individuals to study epigenetic mechanisms in cancer. \nExperimental duties will include but not be limited to\, using molecular biology techniques such as cell culture\, western blotting\, Chromatin immunoprecipitation\, CRISPR/Cas9 gene editing and next generation sequencing (RNA-seq\, ChIP-seq) to test how structural and functional mutations in proteins that regulate chromatin structure may alter gene expression and promote the tumor phenotype. Additional duties associated with the position may include performing experiments in mice and assisting in the maintenance of the lab’s animal colony and occasional lab maintenance/housekeeping/ordering. Excellent written and oral English language skills are required. Prior experience with mouse models\, flow cytometry\, western blotting and PCR is preferred but not required. In addition\, it is essential that the candidate can work independently in the lab\, maintain an electronic lab notebook describing their research activity\, participate in lab meetings and display good interpersonal skills.
URL:https://ces.b2sg.org/event/uf-25may18/
LOCATION:University of Florida\, Gainesville\, FL\, 32611\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180525
DTEND;VALUE=DATE:20180627
DTSTAMP:20260824T001005
CREATED:20180525T093115Z
LAST-MODIFIED:20180525T093219Z
UID:20259-1527206400-1530057599@ces.b2sg.org
SUMMARY:Postdoctoral Associate - Functional Genetics of Cancer
DESCRIPTION:Our group is interested in the functional genetics of cancer. We use state of the art technology in genomics\, proteomics and epigenetics to understand the molecular mechanisms that drive cancer progression\, metastasis and chemoresistance. We are recruiting a postdoctoral fellow to work on understanding the functional consequences of combinations of mutations that contribute to tumorigenesis. Highly self-driven\, ambitious candidates with a knack for solving challenging problems in cancer biology and outstanding publication track record are encouraged to apply. The candidate is expected to work as a part of multi-disciplinary\, dynamic and vibrant team\, and will have the opportunity to work and develop his/her research program with the best in the field. \n  \nEducation and/or Experience: \nYou hold a PhD degree or equivalent in bioinformatics\, statistics\, computational biology\, or related discipline of biomedical research. Experience in computational and statistical genetics\, genomics and knowledge of R and PERL and their application in cancer research is mandatory. Programming experience is required as is having worked with big data. It is desired that you are familiar with standard molecular biology\, tissue culture practices and mouse genetics protocol. The successful candidate will have strong qualifications or experience within several of the following areas: \n\nBioinformatics and systems biology at the molecular level\nCancer pathophysiology and RNA biology of Cancer.\nProject management of interdisciplinary research projects within genomics and bioinformatics (Genomics\, Non-coding RNAs\, Proteomics and Chromatin Biology)\nExperience with data structures\, databases\, and data architectures (TCGA\, SU2C etc)\nKnowledge of biomedical resources and infrastructures
URL:https://ces.b2sg.org/event/sbp-25may18/
LOCATION:Sanford Burnham Prebys Medical Discovery Institute\, 10901 N Torrey Pines Rd\, La Jolla\, CA\, 92037\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180527
DTEND;VALUE=DATE:20180629
DTSTAMP:20260824T001005
CREATED:20180527T131832Z
LAST-MODIFIED:20180527T132216Z
UID:20262-1527379200-1530230399@ces.b2sg.org
SUMMARY:Associate Research Scientist
DESCRIPTION:Apply On Company Site\n\n\n\n\nColumbia University invites applications for a molecular biologist appointment in the Department of Pathology and Cell Biology at the Columbia University Medical Center in Dr. Kevin Gardner’s Lab. Positions are available to study basic mechanisms of epigenetic gene regulation and transcriptional control in breast cancer. The lab has an integrated focus on fundamental mechanisms of chromatin-based transcriptional control\, including basic mechanisms of epigenetic regulation and enhancer function (Proc Natl Acad Sci U S A. 2009 Nov 17;106(46): 19286-91; Nat Struct Mol Biol. 2010 Dec;17(12): 1406-13; Nat Commun. 2012 Jan 17;3:633; Nat Commun. 2013;4:1449). New initiatives include the application of these methods and approaches to translational research to improve the diagnosis\, treatment and prevention of breast cancer. Central themes are understanding the role of transcriptional cross-talk and intersections receptor-mediated signaling pathways in the control of enhancer-mediated influence on gene expression. A major goal in the lab is the development omic perspectives that integrate next-generation sequencing with genomics\, transcriptomics\, epigenomics\, proteomics and metabolomics. The projects will be supported by access to an established diverse cohort of breast cancer patient samples with deep next generation molecular genomic characterization for both gene and pathway discovery and translation application in diagnosis\, treatment\, and prevention.  \nMinimum Degree Required:\n Ph.D. / M.D. or both  \nMinimum Qualifications:\n All applicants MUST meet these minimum qualifications to be considered for the position.  \nCandidate must have background in one or more our current research specialties: Cancer Biology\, Neurodegenerative diseases\, Cellular and molecular neurobiology\, Cell motility\, Cytoskeleton and intracellular trafficking\, Virology\, Molecular Biology\, Neuronal stem cells and Anatomic or Clinical pathology.  \nPreferred Qualifications:\n Ph.D. or M.D. equivalent in areas molecular biology or related field. Expertise in the construction sequencing libraries for various genomic analytical platforms including RNA-seq\, Exome-sequencing\, and ChIP-seq is required. Experience in the performance and analysis of ChIP-seq is required. Familiarity with CRISPR/Cas9 technology and ATTAC-seq analysis is highly desirable. An understanding of bioinformatic approaches and technologies in manipulating and interpreting deep sequencing data would be a significant advantage. We are looking for individuals with a strong desire to work on fundamental research questions in cancer and chromatin biology. Those candidates with a proven research experience and a history of an ability to independently drive a project forward in an interactive environment\, with willingness to provide mentorship to junior lab members\, would be highly competitive. 
URL:https://ces.b2sg.org/event/cu-27may18/
LOCATION:Columbia University Medical Center\, 630 W 168th St\, New York\, NY\, 10032\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180528
DTEND;VALUE=DATE:20180630
DTSTAMP:20260824T001005
CREATED:20180528T095714Z
LAST-MODIFIED:20180528T095806Z
UID:20265-1527465600-1530316799@ces.b2sg.org
SUMMARY:Assistant\, Associate or Full Professor - Cancer Biology
DESCRIPTION:The Department of Cancer Biology at the Perelman School of Medicine at the University of Pennsylvania seeks candidates for a Full\, Associate\, and/or Assistant Professor position in the tenure track. The successful applicant will have experience in the field of cancer biology\, including but not limited to tumor immunology\, chemical biology\, cancer metabolism\, cancer genetics and epigenetics\, cancer cell biology\, tumor microenvironment\, stem cells\, and metastasis. Responsibilities include maintenance of an externally funded independent research program\, as well as teaching and mentoring of students. Applicants must have an Ph.D. and/or M.D. degree and have demonstrated excellent qualifications in research and education. \nWe seek candidates who embrace and reflect diversity in the broadest sense. \nThe University of Pennsylvania is an EOE. Minorities/Women/Individuals with disabilities/Protected Veterans are encouraged to apply. \n\nApply for this position online at: https://www.med.upenn.edu/apps/faculty_ad/index.php/g/d4794
URL:https://ces.b2sg.org/event/upenn-28may18/
LOCATION:University of Pennsylvania\, 3400 Civic Center Blvd\, Philadelphia\, 19104\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180528
DTEND;VALUE=DATE:20180630
DTSTAMP:20260824T001005
CREATED:20180528T101708Z
LAST-MODIFIED:20180528T101708Z
UID:20269-1527465600-1530316799@ces.b2sg.org
SUMMARY:Faculty Position - Gene Regulation\, Genomics\, and Reproduction
DESCRIPTION:The Cecil H. and Ida Green Center for Reproductive Biology Sciences\, an endowed basic science research center within the University of Texas Southwestern Medical Center Department of Obstetrics and Gynecology\, is recruiting to fill a newly created Tenure-track Assistant Professor Position. We invite applications from outstanding candidates studying aspects of signaling\, gene regulation\, and genome function\, especially in the areas of chromatin and transcription\, epigenetics\, nuclear endpoints of cellular signaling pathways\, nuclear receptors\, RNA biology\, genome organization\, and genome evolution. We are interested in a wide variety of model systems and experimental approaches\, including biochemistry\, molecular biology\, structural biology\, animal models\, genetics\, genomics\, proteomics\, bioinformatics\, and computational biology. The Green Center’s research programs focus on\, but are not limited to\, reproduction and development in a broad sense\, as well as aspects of endocrinology\, stem cells\, cancer\, metabolism\, inflammation\, immunity\, and neurobiology. For this search\, we are particularly interested in recruiting a candidate who represents one or more of these areas of biology:\n\n\nSignaling\, chromatin\, and gene regulation\, using a wide array of experimental approaches to address fundamental questions in nuclear signaling\, chromatin\, transcription\, epigenetics\, and RNA biology.\n\n\nMolecular biology of female reproductive systems\, from stems cells\, oncogenesis\, and fertilization\, to implantation\, placental function\, pregnancy\, and parturition\, using cell-based or physiological models in combination with molecular or genomic approaches.\n\n\nGenomic\, bioinformatic\, computational\, and evolutionary approaches to understanding gene regulation\, using state-of-the-art genomic and computational tools.\n\n\nThe Green Center promotes and supports cutting-edge\, integrative\, and collaborative basic research in reproduction\, development\, and related areas of biology\, as well as strong connections between basic and clinical research. This recruitment is part of a major university and department-supported renovation and rejuvenation of The Green Center over the past 7 years. Successful candidates will be housed in a newly renovated state-of-the-art research facility and provided a generous start-up package\, and are expected to establish scientifically rigorous and externally funded research programs and participate in center\, department\, and university teaching and training programs. To learn more about The Green Center\, visit: \nhttp://www.utsouthwestern.edu/education/medical-school/departments/green-center/index.html \nCandidates must have a Ph.D. or M.D. or equivalent in a relevant field of study\, postdoctoral or comparable experience\, and a demonstrated record of research excellence. Applicants should send a letter of application\, curriculum vitae\, and a statement of planned research projects as pdf files to GreenCenter@UTSouthwestern.edu. Please indicate one of the three research areas listed above (Molecular biology of female reproduction; Gene regulation; Genomics) in the subject line of the email. Applicants should also arrange for three letters of reference to be sent directly to the above e-mail address. Review of applications will begin on October 30\, 2017\, and will continue during the 2017–2018 academic year or until the position is filled\, although applicants are encouraged to submit their materials as soon as possible.
URL:https://ces.b2sg.org/event/utsw-28may18/
LOCATION:UT Southwestern Medical Center\, 5323 Harry Hines Blvd.\, Dallas\, TX\, 75390\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180529
DTEND;VALUE=DATE:20180701
DTSTAMP:20260824T001005
CREATED:20180529T095017Z
LAST-MODIFIED:20180529T095017Z
UID:20271-1527552000-1530403199@ces.b2sg.org
SUMMARY:Faculty Positions (DOQ)
DESCRIPTION:Huntsman Cancer Institute (HCI) and the Department of Oncological Sciences at the University of Utah Health Sciences Center seeks outstanding candidates for faculty positions at all levels and at all ranks in basic and translational cancer research. \nHCI is an NCI-designated Comprehensive Cancer Center and a member of the National Comprehensive Cancer Network (NCCN)\, supporting and fostering a vibrant research enterprise in a highly collegial environment. HCI has a strong history of academic achievement and impact as well as a commitment to excellence in patient care\, research\, teaching and service. \nHCI has made a strategic commitment to develop disease-oriented research teams (DOTs) as a mechanism to enhance translational research. DOTs specialize in adult and pediatric cancer research in the following areas: Colon Cancer\, Genitourinary and Hematologic Malignancies\, Hepatobiliary Cancer\, Melanoma\, Neuro-Oncology\, Pancreatic Cancer\, Sarcoma\, Upper Aero Digestive Tract (with existing strengths in lung cancer) and Women’s Cancers. Candidates whose research interests are aligned with these DOTs are strongly encouraged to apply. \n1. Basic Cancer Research:\nWe seek junior and senior investigators with innovative research programs in cancer-relevant biology that emphasize mechanistic approaches. Areas of interest include signal transduction\, stem cells\, gene regulation & transcription\, chromatin & epigenetics\, genome stability & DNA repair\, metabolism\, cancer genetics\, metastasis\, epithelial biology\, tumor immunology\, hematologic malignancies\, pediatric/youth cancers\, and mechanisms of therapy resistance. \n2. Translational Cancer Research:\nThis broad-based recruitment seeks outstanding junior or senior investigators in areas including\, but not limited to: animal models\, signal transduction\, cancer genetics\, target validation\, drug discovery & validation\, epigenetics & gene expression\, DNA damage & repair\, tumor immunology\, cancer initiating cells\, and clinical cancer research. Candidates whose scientific interests will synergize with the clinical strengths of the HCI DOTs are particularly encouraged to apply. \nHCI and the University Health Sciences Center provide access to state-of-the-art equipment and services through exceptional Core Facilities (see www.cores.utah.edu) that enhance both discovery and translational science. HCI offers state-of-the-art laboratories\, including a new 225\,000 sq. ft. research building that doubles the Institute’s research space\, which opened summer 2017. The University of Utah offers excellent graduate programs for training PhD and MD/PhD students. For more information about HCI\, visit www.huntsmancancer.org. \nApplicants for Assistant Professor are expected to hold MD\, PhD\, or MD/PhD (or equivalent)\, have received appropriate postdoctoral training\, and to have a track record of impact and research productivity. Applicants for senior positions should additionally have a strong record of independent funding and innovative research. HCI particularly encourages and welcomes applications from physician-scientists across the continuum of cancer research. Highly competitive recruitment packages are available with appointment and rank in an academic department at the University of Utah determined by the applicants’ qualifications. \nCandidates should submit a curriculum vitae\, cover letter containing a description of professional experience (including scientific accomplishments\, leadership responsibilities and 3 references)\, and a 2-3 page research plan. Applications will be accepted continuously\, with evaluations beginning November 10\, 2017\, until positions are filled or closed. \nTo apply online\, please visit the following link:\nhttp://utah.peopleadmin.com/postings/69239 \nOr\, send to:\nHuntsman Cancer Institute\nAttn: Recruitment Office\, Room 5160\n2000 Circle of Hope\, Salt Lake City\, UT 84112-5550\nEmail: hci.recruitment@hci.utah.edu \nFor questions\, please contact Natalie Angle at hci.recruitment@hci.utah.edu
URL:https://ces.b2sg.org/event/utah-29may18/
LOCATION:University of Utah\, 201 Presidents Cir\, Salt Lake City\, 84112\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180529
DTEND;VALUE=DATE:20180701
DTSTAMP:20260824T001005
CREATED:20180529T100715Z
LAST-MODIFIED:20180529T100715Z
UID:20273-1527552000-1530403199@ces.b2sg.org
SUMMARY:Post-Doctoral Fellow
DESCRIPTION:Post Doctoral Fellow positions (2) are available in laboratory of Dr. Kavitha Sarma at The Wistar Institute\, member of Penn Epigenetics Institute in Philadelphia.  Candidates must be highly motivated\, enthusiastic and interactive scientists with interests in gene regulation\, chromatin biology and epigenetics. A strong background in molecular biology and protein biochemistry and experience in mammalian cell culture is required.  Candidates with experience in RNA-Seq and ChIP-Seq technologies are preferred. \n\nCandidates should have a PhD degree and must have at least one first author peer reviewed publication. Application must include the following documents: \n\n\nA CV including a list of publications\, manuscripts in preparation\, and technical skills.\nOne-page cover letter stating reasons for their scientific interest in the lab and career goals.\nNames and contact information for at least 3 references to ksarma@wistar.org.
URL:https://ces.b2sg.org/event/wistar-29may18/
LOCATION:Wistar Institute\, 3601 Spruce Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180530
DTEND;VALUE=DATE:20180702
DTSTAMP:20260824T001005
CREATED:20180530T105455Z
LAST-MODIFIED:20180530T105455Z
UID:20299-1527638400-1530489599@ces.b2sg.org
SUMMARY:Research Laboratory Technician
DESCRIPTION:A Research Laboratory Technician position is available to work on brain tumors research. Working independently under the direction of the Principal Investigator Dr. Mario Suvà in the research laboratory within the Department of Pathology\, MGH\, the Research Technician II is required to develop and successfully implement various new technologies and coordinate computational data analysis.\nPRINCIPAL DUTIES AND RESPONSIBILITIES:\nThe principle responsibility of the technician is to carry out the technical aspects of molecular testing and cancer epigenetics in gliomas\, with the guidance of the PI. The specific responsibilities include:\n· Performing technical components of molecular assays\, including\, but not limited to\, the development\, testing\, and analysis of next-generation sequencing. The laboratory is developing two technologies applied directly to patient tumors: single cell RNA- sequencing and epigenomic profiling by chromatin-immunoprecipitation\n· Derivation of short-term primary cultures from patient tumors\n· Perform functional genes knock-out using novel genome-editing technologies such as the CRISPR/cas9 system. Perform in vitro drug treatment of primary cancer cell lines\, and analysis of cell responses using immunohistochemistry and western blotting\n· Ensuring specimen integrity\n· Routine lab tasks including glassware cleaning and equipment maintenance and QC programs (on a shared schedule)\n· Ensuring patient privacy and compliance with HIPAA guidelines\n· Maintaining and updating the Research laboratory manual in accordance with the regulations\n· Education of residents\, fellows\, medical students and technicians\n· Work in a collaborative fashion with other group members\n· Manages orders for the lab\nSKILLS/ABILITIES/COMPETENCIES REQUIRED :\n\nExcellent communication skills\, both oral and written.\nAbility to identify problems and develop solutions.\nFamiliarity with molecular biology\, computers and the metric system.\nKnowledge of next-generation sequencing.\nFamiliarity and understanding of the concepts of molarity\, normality\, molecular weight\, formula weight of chemicals.\nMust be familiar with how to make dilutions from stock solutions.\nKnowledge of good laboratory techniques and the scientific method.\nAbility to do mathematical calculations.\nMust know the proper handling procedure of chemicals and sterile tissue culture technique.\nAbility to prioritize\, work within deadlines and multi-task.\nHigh degree of computer literacy.\n\n\n\nQualifications\nEDUCATION:\nBA/BS degree in Biological or Physical Sciences required.\nEXPERIENCE :\nA minimum of 1-2yrs of directly related and progressively more responsible experience.\nPrevious experience in epigenomic profiling and RNA-sequencing is required.
URL:https://ces.b2sg.org/event/mgh-30may18/
LOCATION:Massachusetts General Hospital Cancer Cente\, 55 Fruit St\, Boston\, MA\, 02114\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180601
DTEND;VALUE=DATE:20180702
DTSTAMP:20260824T001005
CREATED:20180601T072518Z
LAST-MODIFIED:20180601T072518Z
UID:20324-1527811200-1530489599@ces.b2sg.org
SUMMARY:Postdoctoral Associate
DESCRIPTION:An exciting opportunity is available to join a cancer pharmacology lab that emphasizes pharmacokinetic (PK)\, pharmacodynamic (PD)\, and quantitative systems pharmacology (QSP) approaches to study brain tumors. The lab integrates experimental data with mathematical models or QSP models to characterize drug action and predict drug responses in patients. The ultimate goal is to bridge preclinical and clinical drug development paradigms and advance precision medicine. \nThe postdoctoral position is in the lab of James M. Gallo in the Department of Pharmaceutical Sciences\, School of Pharmacy and Pharmaceutical Sciences at the University at Buffalo. The department is a premier research unit with a storied tradition of excellence in PK/PD research. Ongoing projects are in anticancer drug development\, drug resistance\, cell state\, epigenetics and tumor heterogeneity. \nThe postdoctoral associate will join a highly interactive department with a central focus of PK/PD/QSP modeling\, and have opportunities to interact with highly talented graduate students\, and scientists within the university including Roswell Park Cancer Institute. Position responsibilities include: \n• Develop PK/PD/QSP models using a variety of computer programs.\n• Participate in lab meetings and contribute to the training of students and lab personnel in advanced modeling methods.\n• Interact positively with scientific personnel across different disciplines to advance QSP.\n• Provide expert support of computer systems used for the labs modeling efforts. \n• Maintain abreast of current literature in the fields relevant to lab projects.\n• Provide reports based on your work for scientific publications and extramural funding applications.\n• Advance your knowledge of QSP modeling methods and implement those as needed \n\nMinimum Qualifications: \n• Ph.D. in Engineering\, Mathematics\, Pharmacometrics\, Systems Biology/Pharmacology or a related field.\n• Demonstration of mathematical modeling & computer simulation experience; preferably related to biomedical/pharmaceutical applications. \n• Expertise in Matlab/SimBiology/Simulink. \n• Additional familiarity with R\, JDesigner/Systems Biology Workbench and related programs desirable.
URL:https://ces.b2sg.org/event/ub-1jun18/
LOCATION:University at Buffalo\, Buffalo\, NY\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180601
DTEND;VALUE=DATE:20180703
DTSTAMP:20260824T001005
CREATED:20180601T100340Z
LAST-MODIFIED:20180601T100440Z
UID:20326-1527811200-1530575999@ces.b2sg.org
SUMMARY:Postdoctoral Associate
DESCRIPTION:We are seeking a highly motivated Postdoctoral Associate to join the newly established Agarwal lab at Texas Children’s Cancer Center and the Department of Pediatrics\, Baylor College of Medicine. This position will assist the PI in performing complex research experiments\, handling the mouse colony\, drafting manuscripts\, and to upkeep the laboratory. \n\nImplement flow cytometry based assays\nCloning\nLaboratory experiments including MTT assays\, soft agar assays\, Western Immunoblotting\, PCR and q-PCR\nUpkeep of laboratory and equipments\nTrain junior laboratory personnel\nAssist the PI in experiments\nManuscript preparation\n\nRequired: Recent PhD with experience and interest in molecular oncology and epigenetics. \n\nIdeally\, the candidate should have prior experience and comfort in handling and maintaining mouse colony\, xenograft tumor assays\, mouse imaging\, mouse tissue extraction and molecular analysis.\nExcellent communication skills\, research ethics\, laboratory record keeping\, and data analytic skills are required.
URL:https://ces.b2sg.org/event/bcm-1jun18/
LOCATION:Baylor College of Medicine\, 1 Baylor Plaza\, Houston\, TX\, 77030\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180602
DTEND;VALUE=DATE:20180704
DTSTAMP:20260824T001005
CREATED:20180602T194956Z
LAST-MODIFIED:20180602T194956Z
UID:20331-1527897600-1530662399@ces.b2sg.org
SUMMARY:Cancer Faculty Investigators
DESCRIPTION:The University of Alabama at Birmingham (UAB) Comprehensive Cancer Center (CCC) is leading the recruitment of multiple investigators (up to 15) for a major strategic increase in its portfolio across basic and translational research efforts. Recruitment is for tenured\, tenure-track\, and non-tenure-earning faculty at all ranks and includes academic appointment in one or more of 27 academic departments across the School of Medicine (SOM)\, many of which rank in the top 10 nationally in NIH funding. All applications will be considered\, but priority will be given to those with emphasis (or focused) in: tumor immunology and inflammation\, cancer cell metabolism\, epigenetics\, oncolytic viruses\, cancer outcomes and survivorship\, role of the microbiome in cancer\, cancer imaging\, chemoprevention and informatics. Likewise\, we are interested in research involving the following organ systems: ovary\, breast\, lung\, GU\, GI\, brain and hematologic malignancies including multiple myeloma. \nDriven by an intensely collaborative and entrepreneurial character\, UAB is one of the leading economic engines of the State\, with a nearly $4 billion budget and a statewide economic impact exceeding $7 billion annually. UAB is Alabama’s largest employer with more than 23\,000 employees; it supports more than 64\,000 jobs statewide. With more than 1\,300 full time faculty and almost 1\,200 medical and graduate students\, the UAB SOM ranks 23rd nationally in NIH research funding and in the top 10 for all public institutions. Total research expenditures at UAB exceeded $538 million in 2017. \nSuccessful applicants will join one of the most prestigious comprehensive cancer centers in the country. The UAB CCC was one of the first eight NCI-designated Cancer Centers in 1972 and has been continuously funded for 46 years. It is the only CCC in a four-state region in the Deep South. The UAB CCC treats over 5\,000 new cancer patients annually and has an extensive effort focused on delivering cancer care and conducting research in underserved populations. The UAB CCC has over 400 members conducting outstanding cancer research in six scientific programs. Center members receive approximately $100 million in extramural cancer research funds annually\, including multiple program project and large “team science” grants. The UAB CCC has 12 grant-supported cores\, 9 of which are institutional shared resource facilities. A robust clinical trial infrastructure currently supports nearly 200 cancer clinical trials. UAB is one of 42 institutions with an NIH Clinical and Translational Science Award\, which supports translational research and creates a supportive environment that synergizes with the UAB CCC to promote junior investigators. \nApplicants must upload their Curriculum Vitae\, one page letter of interest\, and 3 professional references to http://uab.peopleadmin.com/postings/4116. Application deadline is July 15\, 2018. Review of applications will continue until all positions are filled. Applicants must have an MD\, PhD or MD/PhD. Selected applicants will join a diverse and vibrant academic community that values and is committed to diversity\, equity and inclusion and must be able to work in a team environment.
URL:https://ces.b2sg.org/event/uab-2jun18/
LOCATION:University of Alabama at Birmingham\, 1801 University Blvd\, Birmingham\, AL\, 35233\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180603
DTEND;VALUE=DATE:20180705
DTSTAMP:20260824T001005
CREATED:20180603T060057Z
LAST-MODIFIED:20180603T060057Z
UID:20346-1527984000-1530748799@ces.b2sg.org
SUMMARY:Postdoctoral Fellowship
DESCRIPTION:A Postdoctoral Fellow position is available in the laboratory of Dr. Sangeeta Dhawan\, at the Diabetes and Metabolism Research Institute ( https://www.cityofhope.org/research/diabetes-metabolism-research-institute) at City of Hope. We are looking for a highly motivated postdoctoral fellow interested in studying the epigenetic regulation of pancreatic beta-cell mass in health and diabetes. In addition\, our lab is interested in the dynamics of beta-cell diversity\, islet organization and cell-cell interaction in fetal and neonatal development. The Dhawan lab utilizes genetic mouse models\, molecular biology and epigenetic techniques to study the cellular identity\, function\, remodeling\, and survival of beta-cells in physiological and pathological conditions.  \nThe specific research projects currently available in the lab are directed at determining: the role of epigenetic mechanisms in co-regulation of insulin secretion and beta-cell survival\, epigenetic patterning and remodeling in beta-cell differentiation\, epigenetic regulation of beta-cell adaptive responsive to changes in metabolic demand and injury\, and epigenetic dysregulation in beta-cell failure during diabetes pathogenesis.  \nThe ideal candidate will have extensive experience in molecular biology and cell or developmental biology. Experience with epigenetic techniques and rodent models preferred. ÃThe candidate should be self-motivated\, with a proven track record of productivity.  \nTo apply\, please send your CV\, a list of three references\, and a summary of research interest to sdhawan@coh.org .  \nFor details of our research and published work\, please visit:\nhttps://www.cityofhope.org/sangeeta-dhawan  \nMinimum Education and Skills Required for Consideration:\nPhD in Molecular\, Cellular or Developmental Biology.  \nStrong interest in diabetes research/regenerative biology.  \nExtensive experience with basic molecular biology skills.  \nExperience in handling animal models preferred.  \nExperience with epigenetic techniques preferred.  \nExperience with tissue collection\, histology and immunohistochemistry.  \nExperience with cell culture\, immunofluorescence\, flow cytometry\, and cell-sorting.  \nStrong work ethic.  \nExcellent written and verbal communication skills. Evidence of productivity reflected in first author publications in peer-reviewed journals.  \nGood problem solving skills and passion to follow relevant literature.  \nAbility to conduct independent research\, and work effectively in a team. 
URL:https://ces.b2sg.org/event/hope-3jun18/
LOCATION:City of Hope\, 1500 East Duarte Road\, Duarte\, 91010\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180603
DTEND;VALUE=DATE:20180705
DTSTAMP:20260824T001005
CREATED:20180603T060954Z
LAST-MODIFIED:20180603T060954Z
UID:20348-1527984000-1530748799@ces.b2sg.org
SUMMARY:Research Intern
DESCRIPTION:A full-time position as a Research Intern is available in Dr. Jennifer Trowbridge’s lab\, focusing on stem cell biology in blood system aging and blood cancer. This position will involve conducting basic\, hypothesis-driven research on hematopoietic stem cells and leukemia stem cells to understand the mechanisms governing stem cell self-renewal\, differentiation and how deregulation of epigenetic modifications leads to leukemia. See https://www.trowbridgelab.com for more details about our research efforts and current team members. \n  \nThe Research Intern position is a temporary\, mentored position lasting up to 36 months and is designed specifically for individuals with a 4 year Life Science\, Biology or applicable degree looking to advance their scientific/research training prior to pursuing further education (graduate-level or medical degree). During the internship\, Interns are eligible to apply for permanent positions at JAX as long as performance is rated satisfactory by their Scientific Advisor\, but a permanent position is not guaranteed. \n\nKey Responsibilities: \n\nExpand subject matter expertise through investigation of the primary literature towards effective study design and independent research project leadership.\nSuccessful execution of complex tests\, experiments and procedures in the context of a larger study design; and ability to recognize and implement quality control measures where needed.\nData analysis and design of data documentation / reporting; leads efforts to modify and adapt research methodologies; ensures compliance with regulatory standards.\nPreparation of research reports\, literature reviews\, scientific papers\, and/or assistance with drafting and generating preliminary data for research proposals in consultation with the Principal Investigator; develops and delivers presentations at lab meetings as well as to the larger Laboratory community and external scientific community.\nOperate and troubleshoot highly specialized equipment.\n\nRequired Skills \n\nBachelor’s degree in life sciences\, biological sciences or related discipline.\nPrevious experience in an academic setting performing experiments\, interpreting and evaluating results\, and compiling data preferred.\nExplicit interest in pursuing and completing eligibility requirements for continuing studies in biomedical research or in pursuing a medical degree.\nThe ability to work in a demanding\, fast paced\, team-oriented environment\, while maintaining a high-level of professionalism.\nAbility to develop technical documents and presentations.\nAbility to work flexible shifts (evening/week-end/holiday).\n\n\nA cover letter outlining general interests\, and career goals should be submitted with CV/Resume as one document to consider application complete.
URL:https://ces.b2sg.org/event/jax-3jun18/
LOCATION:Jackson Laboratory\, 600 Main Street\, Bar Harbor\, ME\, 04609\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180604
DTEND;VALUE=DATE:20180706
DTSTAMP:20260824T001005
CREATED:20180604T185043Z
LAST-MODIFIED:20180604T185621Z
UID:20362-1528070400-1530835199@ces.b2sg.org
SUMMARY:Postdoctoral Fellowship
DESCRIPTION:Two Postdoctoral Fellow positions are immediately available in the laboratory of Dr. Ke Ma\, Associate Professor\, at the Diabetes and Metabolism Research Institute (https://www.cityofhope.org/research/diabetes-metabolism-research-institute) at City of Hope in Los Angeles. By applying state-of-the-art circadian biology to diabetes and obesity research\, Ma lab has established a unique research niche to dissect the coordinated control of circadian clock circuit in metabolic tissue growth and functional capacity.  The broad goal of our research is to better understand the temporal control in metabolic diseases to uncover circadian etiologies underlying the development of diabetes and cancer for targeted therapeutic interventions. We are looking for highly motivated postdoctoral fellows to study novel signaling and epigenetic mechanisms mediating circadian clock functions in adipose tissue and skeletal muscle. Our research utilizes biochemical and molecular biology approaches in genetic mouse models and circadian biology. Specific research directions in Ma Lab will explore\, 1)\, epigenetic networks mediating clock nutrient-sensing function in adipose tissue and skeletal muscle\, 2)\, circadian clock regulation of skeletal muscle growth\, development and metabolism\, and 3)\, novel roles of circadian regulators in cancer development and metabolism. \nThe candidate should be self-motivated\, with a proven track record of productivity and strong interest in metabolic disease research. Expertise in biochemistry\, molecular biology and animal metabolic studies is preferred\, and technical skill in stem cell research and epigenetics is a plus. To apply\, please provide your CV and a list of three references. \nMinimum Education and Skills Required for Consideration: \n\nPhD in Molecular\, Cellular or Developmental Biology.\nProficiency with biochemical techniques\, molecular biology skills and cell culture systems.\nExperience with in vivo animal model research preferred.\nExperience with stem cell research preferred.\nExperience with epigenetics research a plus.\nHighly motivated and strong research interest in metabolic disease.\nStrong work ethic and ability to work effectively in a team.
URL:https://ces.b2sg.org/event/hope-4jun18/
LOCATION:City of Hope\, 1500 East Duarte Road\, Duarte\, 91010\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180606
DTEND;VALUE=DATE:20180708
DTSTAMP:20260824T001005
CREATED:20180605T180145Z
LAST-MODIFIED:20180606T090016Z
UID:20365-1528243200-1531007999@ces.b2sg.org
SUMMARY:Research Associate 1-B/H
DESCRIPTION:Research Associate 1-B/H (Job Opening 439646) – Research Associate 1-B/H participates in planning\, design\, execution\, and management of research projects in a foundational (basic) biological/health science research laboratory investigating genetic\, epigenetic\, and proteomic modifications and experimental therapeutic techniques for the treatment of various cancers in the Comprehensive Cancer Center; participates in developing and implementing goals and objectives of studies; designs and executes complex laboratory experiments; performs advanced molecular and cellular techniques; collects\, analyzes and interprets research data; assists with development and implementation of new and/or revised research methodologies and techniques; tests experimental designs\, sampling techniques\, and analytical methods and make recommendations for utilization; assists in establishment of controls\, criteria and research standards; performs critical analysis of literature relevant to research being undertaken; assists in the preparation of research papers and manuscripts for publication and presentation at national and conferences and workshops\, and in the writing of project reports\, articles and other documents; assists principal investigator in the preparation of proposals to obtain new or renewal of extramural funding in support of research; coordinates laboratory activities and work assignments of postdoctoral researchers\, graduate and undergraduate students\, and laboratory research staff; oversees and coordinates periodic maintenance and testing of laboratory equipment; performs additional duties as assigned. \nEducation and experience\nMasters degree in a appropriate biological/health science or an equivalent combination of education and experience is required. Ability to translate\, adapt and apply academic and/or practical knowledge in the conduct of biological/health science research is required. Experience in a biological/health science research capacity is preferred. Requires successful completion of a background check; qualified candidates may be asked to complete a pre-employment physical\, including a drug screen.
URL:https://ces.b2sg.org/event/ohio-6jun18/
LOCATION:Ohio State University\, Columbus\, OH\, 43210\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180607
DTEND;VALUE=DATE:20180709
DTSTAMP:20260824T001005
CREATED:20180607T131529Z
LAST-MODIFIED:20180607T131529Z
UID:20371-1528329600-1531094399@ces.b2sg.org
SUMMARY:Research Technologist 2
DESCRIPTION:This role conducts experimental research lab work and/or assists in design of one or more specific phase(s) of entire project(s). May complete mathematical calculations\, and/or computer tasks and/or assist in judging validity of data. Follows appropriate protocols\, policies\, procedures\, regulations\, Good Clinical and Good Laboratory Practices. Highly-motivated and collaborative scientists that hold a Bachelor Degree in Biology\, Biochemistry or related fields are encouraged to apply. Expertise in mouse work as defined below is specifically required:  \nHusbandry \nBreeding and screening transgenic mice \nTransplantation \nInjections \nDissections \nBlood collection \nSurgical procedures \nDatabase management of colony \nThe Ntziachristos laboratory studies the mechanistic aspects of oncogenesis with an emphasis on transcriptional and  \nepigenetic regulation of acute leukemia. Important questions are related to how oncogenes interact with each other and with epigenetic modulators to influence gene expression programs as well as how their function is related to tridimensional (3D) structure of the nucleus and other biological aspects of cancer cells\, like metabolism and deubiquitination.  \nThe laboratory is a member of the Department of Biochemistry and Molecular Genetics situated in the campus of  \nFeinberg School of Medicine in Northwestern University in the heart of the Chicago metropolitan area. The group has access to cutting-edge technology and facilities and is exposed to the vibrant scientific community of Northwestern University and other research centers in the Chicago area. Scientists in the group have the opportunity to present their work and get feedback in Institutional\, National and International forums  \nSpecific Responsibilities:\nFollowing protocols\, designs\, sets-up and conducts basic experiments. \nAnalyzes and troubleshoots protocols and data obtained from individual experiments and recommends alternatives and suggestions to improve processes\, validity and/or accuracy. \nAdministration  \nMaintains detailed records of results\, which may include collecting\, extracting & entering data. \nManipulates\, interprets &/or presents results. \nPrepares charts & graphs for presentations & publications. \nPerforms scientific literature searches in support of research. \nCompletes portions of grant applications\, manuscripts & publications. \nFinance  \nTracks & summarizes lab supply expenses. \nVerifies accuracy of invoices. \nOrders &/or maintains inventory of reagent\, mice &/or lab supplies. \nPerforms other duties as assigned.  \nMinimum Qualifications:\nSuccessful completion of a full 4-year course of study in an accredited college or university leading to a bachelor’s or higher degree in a scientific major or related; OR appropriate combination of education and experience. \nMinimum Competencies: (Skills\, knowledge\, and abilities.)  \nDemonstrated laboratory experience; \nDemonstrated ability to follow detailed instructions as required by research protocols; \nDemonstrated computer skills\, including spreadsheets and basic computations; \nAttention to detail and accurate record keeping; \nAbility to work independently and in a team environment; \nManual dexterity.  \nPreferred Qualifications:\nHighly-motivated and collaborative scientists that hold a Bachelor Degree in Biology\, Biochemistry or related fields are encouraged to apply. \nPreferred Competencies: (Skills\, knowledge\, and abilities)  \nBasic knowledge of Biochemistry\, cloning techniques\, animal (mouse) handling and flow cytometry analysis and sorting and cell culture is also welcome. \nAs per Northwestern University policy\, this position requires a criminal background check. Successful applicants will need to submit to a criminal background check prior to employment. 
URL:https://ces.b2sg.org/event/nwu-7jun18/
LOCATION:Northwestern University\, 633 Clark St\, Evanston\, IL\, 60208\, United States
CATEGORIES:Jobs
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END:VCALENDAR