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PRODID:-//Cancer Epigenetics Society - ECPv5.3.2.1//NONSGML v1.0//EN
CALSCALE:GREGORIAN
METHOD:PUBLISH
X-WR-CALNAME:Cancer Epigenetics Society
X-ORIGINAL-URL:https://ces.b2sg.org
X-WR-CALDESC:Events for Cancer Epigenetics Society
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TZID:Europe/Paris
BEGIN:DAYLIGHT
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:CEST
DTSTART:20180325T010000
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TZOFFSETFROM:+0200
TZOFFSETTO:+0100
TZNAME:CET
DTSTART:20181028T010000
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180428
DTEND;VALUE=DATE:20180908
DTSTAMP:20260825T005422
CREATED:20180428T131558Z
LAST-MODIFIED:20180428T131558Z
UID:19962-1524873600-1536364799@ces.b2sg.org
SUMMARY:Postdoc Research Associate
DESCRIPTION:This position will employ a wide range of experimental systems and interdisciplinary approaches and provide broad training in 3 areas: a.) control of cell cycle and tumor suppression by the ubiquitin pathway\, b.) tumor metabolism\, and c.) epigenetic control during tumorigenesis and innate immunity with an emphasis on the regulation of DNA de/methylation. The incumbent will be employed to carry out advanced independent and/or directed research to achieve the objectives of the research project. The principal investigator will establish the professional objectives and performance standards for the incumbent and will make annual evaluations. \n\n\n\n\nMinimum Qualifications: \nThis position requires knowledge of the fields\, processes and disciplines of cell biology and cancer metabolism. The position will involve organizing and implementing research plans\, the development of methods of research\, testing and data collection\, analysis and evaluation\, and writing reports containing descriptive\, analytical and evaluative content. The duties require discretion and judgement in carrying out research activities within the predetermined research scope and methodology. A PhD degree in the appropriate biomedical science or related field or discipline\, or the recognized terminal degree\, is required.
URL:https://ces.b2sg.org/event/unc-28apr18/
LOCATION:University of North Carolina – UNC-Chapel Hill\, Chapel Hill\, NC\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180519
DTEND;VALUE=DATE:20180715
DTSTAMP:20260825T005422
CREATED:20180519T171048Z
LAST-MODIFIED:20180519T171231Z
UID:20115-1526688000-1531612799@ces.b2sg.org
SUMMARY:Postdoctoral Associate
DESCRIPTION:An exciting opportunity is available to join a cancer pharmacology lab that emphasizes pharmacokinetic (PK)\, pharmacodynamic (PD)\, and quantitative systems pharmacology (QSP) approaches to study brain tumors. The lab integrates experimental data with mathematical models or QSP models to characterize drug action and predict drug responses in patients. The ultimate goal is to bridge preclinical and clinical drug development paradigms and advance precision medicine. \nThe postdoctoral position is in the lab of James M. Gallo in the Department of Pharmaceutical Sciences\, School of Pharmacy and Pharmaceutical Sciences at the University at Buffalo. The department is a premier research unit with a storied tradition of excellence in PK/PD research. Ongoing projects are in anticancer drug development\, drug resistance\, cell state\, epigenetics and tumor heterogeneity. \nThe postdoctoral associate will join a highly interactive department with a central focus of PK/PD/QSP modeling\, and have opportunities to interact with highly talented graduate students\, and scientists within the university including Roswell Park Cancer Institute. Position responsibilities include: \n\nDevelop PK/PD/QSP models using a variety of computer programs.\nParticipate in lab meetings and contribute to the training of students and lab personnel in advanced modeling methods.\nInteract positively with scientific personnel across different disciplines to advance QSP.\nProvide expert support of computer systems used for the labs modeling efforts.\nMaintain abreast of current literature in the fields relevant to lab projects.\nProvide reports based on your work for scientific publications and extramural funding applications.\nAdvance your knowledge of QSP modeling methods and implement those as needed\n\n\n\n\nMinimum Qualifications\n\n\nPh.D. in Engineering\, Mathematics\, Pharmacometrics\, Systems Biology/Pharmacology or a related field.\nDemonstration of mathematical modeling & computer simulation experience; preferably related to biomedical/pharmaceutical applications.\nExpertise in Matlab/SimBiology/Simulink.\nAdditional familiarity with R\, JDesigner/Systems Biology Workbench and related programs desirable.
URL:https://ces.b2sg.org/event/buffalo-19may18/
LOCATION:University at Buffalo\, Buffalo\, NY\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2018/05/ub-uni-at-buffalo.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180612
DTEND;VALUE=DATE:20180714
DTSTAMP:20260825T005422
CREATED:20180612T085340Z
LAST-MODIFIED:20180612T085340Z
UID:20378-1528761600-1531526399@ces.b2sg.org
SUMMARY:Scientist II
DESCRIPTION:We are seeking a highly motivated and experienced industry scientist to join our Epigenetics Center of Excellence. The successful candidate will have a well-documented background of scientific expertise in epigenetics with a high interest in drug discovery and translational medicine. He/she will work on drug discovery projects focused on epigenetic targets. Specifically\, the candidate will be expected to design\, plan and execute biological studies for identifying new targets in various therapeutic areas and for profiling development compounds within the area of epigenetics. \nThis position requires a PhD in biology\, solid understanding in Epigenetics and at least 5 years of productive research experience in epigenetics\, as evidenced by an excellent publication record. \nSkills/Knowledge Required: \n\nExperience in epigenetic profiling studies (DNA methylation\, RNA-sequencing\, ChIP-sequencing and ATAC-sequencing) and strong knowledge in enhancer-mediated regulation of the genome.\nExperience in single cell transcriptomic and epigenetic profiling is highly desired.\nExperience in target validation\, functional and biomarker cell-based assay development.\nProficient in cell biology including shRNA and CRISPR technologies\nHighly motivated\, innovative and strong team player.\nExcellent time management and organizational skill.\nStrong communication skills\, both written and oral.\nStrong ability to work in a fast-paced environment is essential.\nStrong interpersonal and communication skills with a demonstrated ability for creative thinking and problem solving.Functional/Scientific/Technical Skills:\n• Developing cross-functional scientific knowledge. \n• Draw appropriate conclusions and make recommendations on next steps. \n• Demonstrate ability to write peer reviewed quality work. \n• Able to write invention disclosure for patent application\, technical reports\, technical protocols. \n• Scientific expert in specific area. \n• General awareness of drug discovery and development process. \nTasks and Responsibilities: \n• Acts as a liaison between Project Team and functional area. \n• Lead scientist on projects. \n• Identify and recommend new technology. \n• Provide scientific direction. \n• Ownership of compliance and identification of potential gaps. \n• Potential to manage and/or coordinates workflow on projects. \n• Align science and functional area goals with business strategies. \n• Manage resources appropriately. \nDiscretion/Latitude: \n• Works as an individual contributor. \n• Viewed as an expert within the department. \nCreativity and Problem Solving: \n• Critically assesses projects and formulates ideas to increase success. \n• Contributes ideas and develops case or position inside the department. \n• Able to contribute to multiple projects. \n• Able to recognize patterns/trends in data and apply new research directions. \n• Stays informed of project trends\, issues and organizes priorities related to own work. Communicates and uses this information to increase productivity. \nTeamwork and Influence: \n• Communicates with cross functional team. \n• Directly impact the achievement of workgroup/team goals. \n• Actively represents workgroup/team or department on multi-disciplinary or cross functional teams. \nOrganizational Impact: \n• Direct impact on departmental performance. \n• Impact is achieved by contributing to team efforts. \nBehavioral Competencies: \n• Acts with integrity \n• Analysis of issues \n• Building relationships \n• Coaching and developing others \n• Delivers presentations \n• Develops systems & process \n• Fosters open communication \n• Influence others \n• Innovates and uses sound judgment \n• Manages execution and planning\n\nPrerequisites: \nPh.D. in Biology or related scientific discipline with at least 5 years of relevant epigenetics work experience\, preferred.
URL:https://ces.b2sg.org/event/celgene12jun18/
LOCATION:Celgene\, 86 Morris Ave\, Summit\, NJ\, 07901\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180613
DTEND;VALUE=DATE:20180715
DTSTAMP:20260825T005422
CREATED:20180613T071358Z
LAST-MODIFIED:20180613T071358Z
UID:20381-1528848000-1531612799@ces.b2sg.org
SUMMARY:Postdoctoral Fellow
DESCRIPTION:General Notes \nOne year assignment which can be renewed on an annual basis up to a total of five years. Previous time in a postdoctoral fellow position (whether paid or unpaid) at the University or at any other university counts towards this time limitation (unless the area or discipline changes). Final candidate will need to provide official PhD degree verification documents from the granting institution. \n\n\nRequired Application Materials\n\n\nA Resume is required in order to apply\nA Letter of Interest is required in order to apply.\nA List of 3 References is required in order to apply.\n\n\n\n\nAdditional Information\nPurpose \nPerform research in the lab and program of Dr. Song (Stephen) Yi\, Principal Investigator and Assistant Professor of Oncology at the LIVESTRONG Cancer Institutes. \n\nEssential Functions \nUse systems and computational biology\, bioinformatics\, and proteomics approaches to identify genetic and epigenetic biomarkers\, and synthetic lethal mechanisms underlying cancer and immunity for personalized medicine. Perform bioinformatics data analyses and integrative mechanistic studies in a collaborative environment. Perform projects utilizing functional data from cell lines\, Patient Derived Xenograft (PDX) models and cancer patients. Perform data analysis include genomics\, proteomics\, network biology\, epigenetics and next-generation sequencing. Publish manuscripts\, write and edit grants\, progress reports. Participate in the design of a project. Lead a research effort in the direction set forth by the PI and the specific project. \n\nMarginal/Incidental functions \nOther related functions as assigned. \n\nRequired qualifications \nPh.D. degree in bioinformatics\, systems and computational biology\, cancer biology\, immunology\, or relevant field within the last three years. The Dell Medical School is especially interested in qualified candidates who can contribute to diversity and excellence within the learning health system. At the Dell Medical School we strive to create a vital\, inclusive health ecosystem. To ensure alignment\, we follow these fundamental values: https://dellmed.utexas.edu/culture. \n\nPreferred Qualifications \nExperience with cancer genomics\, CRISPR screens and next-generation sequencing analysis. \n\nWorking conditions \nMay work around standard office conditions Repetitive use of a keyboard at a workstation
URL:https://ces.b2sg.org/event/uta-13jun18/
LOCATION:University of Texas at Austin in Austin
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180614
DTEND;VALUE=DATE:20180716
DTSTAMP:20260825T005422
CREATED:20180614T165724Z
LAST-MODIFIED:20180614T165724Z
UID:20383-1528934400-1531699199@ces.b2sg.org
SUMMARY:Postdoctoral Fellowships
DESCRIPTION:Post-Doctoral Fellow positions are available for ambitious and productive applicants in the laboratory of Dr. Rugang Zhang. The lab investigates novel intervention strategies for unmet clinical needs in ovarian cancer and the role of cellular senescence in cancer or tissue aging. The applicant(s) will work in a dynamic scientific environment and has ample opportunities for interactions with leading investigators in ovarian cancer\, epigenetics or cellular senescence through programmatic funding mechanisms. Applicants should have strong background in one or more of the following disciplines: biochemistry\, molecular and cellular biology\, genome-wide approaches to cancer\, animal models of human cancers or aging\, or bioinformatics.\n\nCandidates should have a PhD (or equivalent) degree or should be close to obtaining their doctoral degree. Candidates committed to an academic career are preferred. Curriculum Vitae and three references should be sent to: Rugang Zhang\, Ph.D. The Wistar Institute\, Philadelphia\, PA 19104. Email: rzhang@wistar.org. Website: https://wistar.org/our-scientists/rugang-zhang
URL:https://ces.b2sg.org/event/wistar-14jun18/
LOCATION:Wistar Institute\, 3601 Spruce Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180615
DTEND;VALUE=DATE:20180717
DTSTAMP:20260825T005422
CREATED:20180615T093948Z
LAST-MODIFIED:20180615T094010Z
UID:20385-1529020800-1531785599@ces.b2sg.org
SUMMARY:Postdoctoral Researcher
DESCRIPTION:The Drapkin laboratory at the University of Pennsylvania (Penn) is seeking to expand its work on tumor development and progression\, cancer genomics and epigenetics\, and lineage dependencies. The goals of the lab are to translate important discoveries into clinically useful diagnostic and therapeutic tools. Several postdoctoral positions are immediately available for outstanding candidates.  \nWe seek candidates with a PhD who have a strong background in biochemistry\, molecular biology\, and basic computational biology.  Preference for candidates with experience in developing and characterizing genetically engineered mouse models will be given. The successful candidate must be well organized and capable of working independently as well as collaboratively. The postdoc should be fluent in English\, possess excellent writing skills\, be able to independently analyze experimental results\, and think creatively. A record of prior publications is required. We interested in highly motivated and talented scientists with a strong work ethic who are committed to solving important questions in cancer biology and are willing to stay at least 4-5 years.  The successful candidate will have completed their graduate degree in or after 2016\, and be a US citizens or permanent residents. \nDr. Drapkin is the Director of the Penn Ovarian Cancer Research Center (OCRC). Established in 2007\, the OCRC serves as a catalyst to promote comprehensive and interdisciplinary research on ovarian cancer. Penn is the oldest and one of the finest medical schools in the United States. It is rich in tradition and heritage and at the same time consistently at the forefront of new developments and innovations in medical education and research. Since its founding in 1765 the School has been a strong presence in the community and prides itself on educating the leaders of tomorrow in patient care\, biomedical research\, and medical education. Penn offers competitive salaries and outstanding benefits. \nVisit the Drapkin lab website for more details: https://www.med.upenn.edu/drapkinlab/ \nPlease submit a motivation letter along with three reference letters and your CV to: \nDr. Drapkin at drapkinlabpostdoc@gmail.com
URL:https://ces.b2sg.org/event/upenn-15jun18/
LOCATION:University of Pennsylvania\, 3400 Civic Center Blvd\, Philadelphia\, 19104\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/05/penn-1-e1494306554396.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180618
DTEND;VALUE=DATE:20180720
DTSTAMP:20260825T005422
CREATED:20180618T170619Z
LAST-MODIFIED:20180618T170824Z
UID:20388-1529280000-1532044799@ces.b2sg.org
SUMMARY:Postdoc Position
DESCRIPTION:A postdoctoral position is available in the Department of Genetics\, UAB Comprehensive Cancer Center and Center for Free Radical Biology at University of Alabama\, Birmingham. Our group has a longstanding interest in understanding role of oxidative stress\, mitochondria-to-nucleus retrograde cross talk\, mitochondria-induced nuclear genomic instability and mitochondrial genetics in tumorigenesis and other human diseases. \nWe have excellent academic environment and research facilities at the Department of Genetics\, UAB Comprehensive Cancer Center and Center for Free Radical Biology. UAB is a major research university and academic health center that offers a highly interactive scientific environment with state-of-the-art research and core facilities and multidisciplinary work environment. The Department of Genetics fosters collaboration with other basic science as well as clinical departments and the UAB Comprehensive Cancer Center. \nThe candidate is expected to be self-motivated\, resourceful and should have a recently obtained Ph. D. degree. Those with interest and experience in mitochondrial biology\, biogenesis\, oxidative phosphorylation and genetics\, epigenetics such as DNA methylation and transgenic mouse and cell culture models of cancer and/or human diseases are strongly encouraged to apply. \nThe candidate must have experience in mitochondrial techniques\, OXPHOS enzymatic assays\, cell culture\, and standard molecular and epigenetic techniques including cloning\, real time PCR\, transfection\, Southern\, Northern and Western analysis and immunoprecipitation. The candidate with experience in tumorigenesis assay such as soft agar\, matrigel invasion and mouse xenograft are also preferred. The successful candidate is expected to design and perform experiments and interpret data independently. \nInterested applicants should email (in pdf format) a cover letter with the description of research interests and experience\, curriculum vitae\, and contact information of three references to mito@uab.edu. The cover letter should be addressed to: \nKeshav K. Singh\, Ph.D.\nJoy and Bill Harbert Endowed Chair\nProfessor of Genetics\, Pathology and Environmental Health\nDepartment of Genetics\, School of Medicine\nUniversity of Alabama at Birmingham\nKAUL 620\, 1530 3rd Avenue South\nBirmingham\, AL 35294-0024
URL:https://ces.b2sg.org/event/uab-18jun18/
LOCATION:University of Alabama at Birmingham\, 1801 University Blvd\, Birmingham\, AL\, 35233\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180619
DTEND;VALUE=DATE:20180721
DTSTAMP:20260825T005422
CREATED:20180619T094906Z
LAST-MODIFIED:20180619T094906Z
UID:20392-1529366400-1532131199@ces.b2sg.org
SUMMARY:Postdoctoral Fellowship
DESCRIPTION:Position Summary and Key Responsibilities:\nPostdoctoral fellow positions are available immediately at Professor Sun’s lab in Beckman Research Institute and the NCI-designated Comprehensive Cancer Center of City of Hope. The successful applicant will join a highly competitive and productive research team to investigate steroid hormone action\, transcriptional control\, and cell signaling in development and tumorigenesis. Specifically\, the applicants will develop and use novel and advanced biological approaches\, and genetically-engineered mouse models to uncover gene-expression and genomic and epigenetic alterations in cancer initiating cells in order to understand mechanisms underlying tumor initiation\, progression\, and metastasis.  \nWe provide a fruitful research and training environment and competitive salary and fringe benefit. Applicants should submit their curriculum vitae and the names of three references. See Zijie Sun lab: http://www.cityofhope.org/people/sun-zijie.  \nMinimum Education and Skills Required for Consideration:\nCandidates should have a recent Ph.D. or M.D/Ph.D. degree in Cancer Biology\, Molecular Biology\, Genetics\, Biochemistry\, Cell Biology\, or a related field. Candidates should be highly self-motivated\, strong working ethic and desire to learn\, and a proven track record of productivity. Previous experience with mouse models of human diseases\, cancer biology\, and cellular and molecular biology is highly desired. 
URL:https://ces.b2sg.org/event/hope-19jun18/
LOCATION:NC
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180620
DTEND;VALUE=DATE:20180722
DTSTAMP:20260825T005422
CREATED:20180620T095512Z
LAST-MODIFIED:20180620T095512Z
UID:20394-1529452800-1532217599@ces.b2sg.org
SUMMARY:Research Lab Technician III/Supervisor
DESCRIPTION:USC’s Keck School of Medicine\, Institute of Urology\, is seeking a Research Lab Technician III/Supervisor to support our Urology Cancer Center epigenetic studies on PSTD and cancer patients pre and post treatment studies. Responsibilities include supervising unit employees and/or student workers as assigned. Assist in orientation and training of unit staff. Plans and conducts research experiments in accordance with laboratory and safety protocols. Independently performs non-routine and complex research laboratory procedures and techniques. Maintains accurate records of procedures used to conduct experiments. Provides input and updates on progress of research as well as selects\, modifies and adapts equipment and maintains sophisticated laboratory and scientific equipment. Controls equipment and supplies inventory. Prepares chemical solutions for experimental use. Researches\, compiles and evaluates background information to enhance planning and design of experiments. \n\nMinimum Education: Bachelor’s degree\, Specialized/technical training \nMinimum Experience: 3 years \nMinimum Field of Expertise: Fully competent and proficient in the operation of sophisticated scientific equipment and independently able to perform complex procedures and techniques with accuracy
URL:https://ces.b2sg.org/event/usc-20jun18/
LOCATION:University of Southern California\, Los Angeles\, CA\, 90007\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180621
DTEND;VALUE=DATE:20180723
DTSTAMP:20260825T005422
CREATED:20180621T163242Z
LAST-MODIFIED:20180621T163242Z
UID:20396-1529539200-1532303999@ces.b2sg.org
SUMMARY:Research Fellow
DESCRIPTION:A Research Fellow position is available in the program of Dr. Keith Robertson. For more information about Dr. Robertson’s program\, please see: http://www.mayo.edu/research/faculty/robertson-keith-d-ph-d/bio-20035097 \nThe successful candidate will join the Epigenetic Etiology of Human Disease Laboratory to study the role of DNA epigenetic modifications in human disease. More specifically\, he/she will examine how DNA methylating and hydroxymethylating enzymes regulate their respective DNA epigenetic modifications and how these marks modulate expression and genome stability\, and interface with other epigenetic modifications. Disease focus areas of the laboratory include cancer (hepatocellular and renal)\, obesity\, and diabetes. Specific research areas include application of genome-wide epigenomics methods to decipher DNA methylation/hydroxymethylation defects in cancer and biochemical/cell culture-based techniques to study the regulation and interactions between chromatin remodeling factors (e.g. DNMTs\, TETs\, HMTases) and the roles of their target loci in driving disease. Techniques commonly used in the laboratory include: quantitative RT-PCR\, western blotting\, cell culture\, transfections\, bisulfite sequencing\, DNA immunoprecipitation\, pyrosequencing\, ChIP-qPCR\, ChIP-seq\, next-gen library preparation and sequencing\, Infinium 850k arrays\, bioinformatics analysis\, microscopy\, and biochemical analysis of protein function. Experience in one or more of these areas is a plus. The candidate will play a major role in the preparation of manuscripts that arise from this work and devote 100% effort to these tasks (no patient contact or other responsibilities). \nPosition description \nA Research Fellow at Mayo Clinic is a temporary position intended to provide training and education in research. Individuals will train in the research program of a Mayo Clinic principal investigator. Qualified individuals will demonstrate the potential for research as evidenced by their training and peer-reviewed publications and should become competitive for national research grants. Proof of English proficiency is required for J-1 Short-Term Scholars\, Research Scholars\, Professors\, Specialists\, and Student Interns sponsored by Mayo Clinic. 800146; J2WRTP \nQualifications \nMust have a Ph.D.\, M.D.\, or equivalent doctoral degree in a field deemed relevant by the program. Research Fellow is appropriate for individuals who have completed no more than one prior postdoctoral fellowship\, at Mayo Clinic or elsewhere. Please attach the following required documents at the time of application: \n\nCurrent curriculum vitae and bibliography\nThree letters of recommendation\, signed\, on letterhead\, describing:\n\nRelationship to the applicant.\nPast work/academic performance.\nWork qualities/personal conduct.\nOverall assessment of potential for success in research environment.\n\n\nDoctoral degree certification\, if applicable:\n\nOriginal or notarized copy of diploma or final transcript issued by school (English translation required).
URL:https://ces.b2sg.org/event/mayo-21jun18/
LOCATION:Mayo Clinic\, 200 1st St SW\, Rochester\, MN\, 55905\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180624
DTEND;VALUE=DATE:20180726
DTSTAMP:20260825T005422
CREATED:20180624T084841Z
LAST-MODIFIED:20180624T085018Z
UID:20401-1529798400-1532563199@ces.b2sg.org
SUMMARY:Associate Scientist
DESCRIPTION:Pfizer’s Oncology Research Unit (ORU) in La Jolla\, California is seeking an Associate Scientist focused on translating basic discoveries in the field of cancer epigenetics into novel therapeutics. \nOur ideal candidate will work within in a collaborative team environment to perform laboratory-based research. The candidate employ genetic and pharmacological to discover and confirm candidates for novel cancer therapeutics. As a member of the group\, you will also be involved in mechanism-of-action studies\, the interpretation and presentation of data\, and will function as an integral member of the team to advance new targets. The successful candidate will have experience in state-of-the-art techniques in epigenomic profiling (ATAC-seq\, ChIP-seq) as well as a basic understanding of epigenetic regulation in the tumor microenvironment. \nROLE RESPONSIBILITIES \nWill report into a team leader within the Epigenetics group. Expected to collaborate with scientists within the Oncology Research Division and across partner lines including Chemistry\, Global Business Technology\, Pharmacokinetics\, Dynamics &Metabolism\, Drug Safety R&D\, Pharmaceutical Science\, and compound management. \nPrimary Duties: \nWork as part of project teams to design\, execute\, analyze/interpret\, and refine experiments ranging from: biochemical and molecular assays\, target modulation\, biomarker assay development. \nDepending upon the stage of project\, specific duties to include: \n\nApplication of genetic and pharmacologic approaches to modulate drug targets in vitro\, and assess functional impact on cancer initiation and progression. This will include functional genomics techniques\, viral vector delivery\, transfection\, antibodies\, small molecules and other pharmacologic approaches to modulate targets in vitro.\nDevelop\, optimize\, and implement assays that constitute the compound screening funnel.\nGenerate engineered cell lines for primary and secondary pharmacology.\nExecute secondary cell-based assays across various technology platforms – qPCR\, ChIP\, RNA-seq\, ATAC-seq\, FACS\, immunofluorescence\, western blotting\, ELISA\, high content screening\, etc.\nApply complex in vitro assays for target validation and secondary pharmacology: spheroid models\, colony forming assays\, 3D co-culture systems.\nCollaborate with in vivo pharmacology group for efficacy testing\, PK/PD and pre-clinical PoC experiments.\nIn addition to efficacy testing\, carry out supporting assays (ELISA\, western blot\, gene expression analysis of tissue lysates) to assess target modulation levels and downstream effects.\nUse electronic data capture/analysis tools such as Excel\, GraphPad\, Biobook\, Spotfire and PowerPoint for experimental documentation and data analysis/presentations.\nPresent research results and methodologies at weekly meetings with immediate supervisor\, at Epigenetic team meetings\, and with members of the oncology research unit as appropriate (example: project team meetings).\nContribute to building a culture that embraces scientific excellence\, urgency\, continuous learning and improvement\, increasing technical skill base and cancer biology expertise; take a proactive role in personal growth and scientific development.\n\nBASIC QUALIFICATIONS \n\nB.S. in Cell Biology\, Molecular Biology (or a comparable biological science) with 0-3 years of related work experience.\nHands on experience with cell-based assays to monitor and analyze effects of target modulation (ELISA\, ICW\, FRET\, Luminescence based assays).\nExperience in functional genomics techniques (CRISPR\, RNAi) for target assessment and generation of cell lines.\nExperience in molecular biology techniques for analysis of chromatin structure/function (ATAC-seq\, ChIP-seq)\, gene expression\, and protein expression\nMust be able to work in a team environment\, have excellent communication skills and be able to present data at project team meetings.\nAbility to master new concepts and techniques quickly.\nStrong attention to detail and organizational skills to manage projects in parallel
URL:https://ces.b2sg.org/event/pfizer-24jun18/
LOCATION:Pfizer – La Jolla\, CA\, 10350 N Torrey Pines Rd\, La Jolla\, CA\, 92037\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180627
DTEND;VALUE=DATE:20180729
DTSTAMP:20260825T005422
CREATED:20180627T162152Z
LAST-MODIFIED:20180627T163128Z
UID:20406-1530057600-1532822399@ces.b2sg.org
SUMMARY:Associate or Full Professor
DESCRIPTION:RPCI is soliciting applications to strengthen its NCI’s Cancer Center Support Grant Program in Cell Stress and Biophysical Therapies (CSBT). Prospective candidates must have a strong record of independent\, extramurally funded program of cancer-related research that will complement the ongoing CSBT Program. Prospective candidates are expected to have active programs in the following areas: molecular (genetic\, epigenetic and biochemical)\, cellular and systemic mechanisms of organismal response to stresses\, pathologies associated with cancer treatment and aging\, as well as development of new original cancer treatment approaches. Proven ability to acquire extramural funding\, along with a strong publication record and other indications of academic activity and visibility are required.  \nRPCI is the world’s oldest cancer center established in 1898\, which is known for numerous basic science and translational discoveries in oncology. RPCI is a NCI-recognized Comprehensive Cancer Center that runs multidisciplinary research combining\, under the umbrella of its CCS Grant\, multiple Programs aimed at understanding\, preventing and curing cancer. It has state-of-the-art research infrastructure enabling all aspects of modern biomedical research – from discovery work towards clinical validation – and provides a highly stimulating academic and clinical environment.
URL:https://ces.b2sg.org/event/rpci-27jun18/
LOCATION:Roswell Park Cancer Institute\, 665 Elm St\, Buffalo\, NY\, 14203\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180630
DTEND;VALUE=DATE:20180802
DTSTAMP:20260825T005422
CREATED:20180630T203206Z
LAST-MODIFIED:20180630T203651Z
UID:20416-1530316800-1533167999@ces.b2sg.org
SUMMARY:Postdoctoral Fellow - Cancer Biology (Myeloma)
DESCRIPTION:Translational Development at Celgene is pleased to present a growth opportunity for outstanding post-doctoral fellows with a passion for hematology-oncology research and clinical development towards improved outcomes in myeloma patient healthcare. The multiple myeloma Translational Development team currently employs state of the art platforms and analytics to address the most important questions that will drive the current and next generation of therapeutic development for myeloma patients. \nThe successful candidate will become part of diverse team with a unified bench-to-bedside vision in precision healthcare and diagnostic approaches to biomarker utilization. The overarching goal of the successful candidate will be to provide\, through passionate research efforts\, clinically implementable information to better understand how patient characteristics\, malignancy biology and immune context features align to define patient outcomes from treatment with portfolio therapeutics and enable rationale combo design. This fellowship will work alongside top shelf scientists with deep knowledge of myeloma disease biology and further expertise including genomic definition of risk and outcomes\, immune characterization\, definition of response and tumoral evolution using single cell platforms and lab-based screens to better understand mechanistics of clinically-observed phenomenon. \nSkills/Knowledge Required: \n\nPhD in cancer biology\, genetics\, epigenetics\nStrong background in disease or mechanism based studies using modern experimental and computational methods is required.\nKnowledge of myeloma is desirable but not required.\nExperience in heme malignancy related areas\nWhile understanding of epigenetics and epigenetic experimental approaches are not essential\, it is highly desirable.\nPrior experience in molecular\, cellular\, functional and computational methods\nAbility to formulate experimental ideas\nDemonstrated writing and commutation skills\nAbility work in a collaborative team science environment
URL:https://ces.b2sg.org/event/celgene-30jun18/
LOCATION:Celgene\, 86 Morris Ave\, Summit\, NJ\, 07901\, United States
CATEGORIES:Jobs
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DTSTART;VALUE=DATE:20180711
DTEND;VALUE=DATE:20180813
DTSTAMP:20260825T005422
CREATED:20180711T105533Z
LAST-MODIFIED:20180711T105533Z
UID:20419-1531267200-1534118399@ces.b2sg.org
SUMMARY:Postdoctoral Fellowship - Genetics\, Epigenetic Regulation
DESCRIPTION:Positions of two postdoctoral scientists are open now in the Chen laboratory ( https://www.cityofhope.org/faculty/jianjun-chen ). Our group is interested in discovering novel genetic and epigenetic regulations and deciphering their underlying molecular mechanisms in normal developmental processes (e.g.\, hematopoiesis) and tumorigenesis (e.g.\, leukemogenesis). We cover research areas with relevance to Hematology\, Immunology\, and Cancer Biology\, with an emphasis on RNA epigenetics (mainly focusing on the N 6 methyladenosine (m 6 A) modification) and DNA epigenetics (mainly focusing on the TET1/2/3-mediated DNA demethylation) associated basic and translational research. Our research involves experiments with primary human cancer cells\, cancer and stem cell transplantation models\, mouse genetics\, classic molecular\, biochemistry and cell biology\, functional genomics\, signal transduction\, and large-scale data analysis and computational biology.  \nMinimum Education and Skills Required for Consideration:\nThe candidates for the Postdoctoral scientist positions should have a Ph.D. and/or M.D. degree(s)\, and a solid background in biochemistry\, mouse model studies\, hematology\, epigenetics\, immunology\, pathology\, and/or stem cell research is preferred for. The candidates should not have more than three years of postdoc training experience. The candidates should be highly motivated individuals with the ability to work in a team environment and with good oral and written communication skills in English.  \nApplication:\nPlease apply to this job posting. Additionally\, your application\, including CV\, brief motivation statement\, and contact information of three scientific mentors (references)\, should be saved as a single PDF. The PDF file can be sent to Dr. Jianjun Chen ( jianchen@coh.org ) directly. 
URL:https://ces.b2sg.org/event/hope-11jul18/
LOCATION:City of Hope\, 1500 East Duarte Road\, Duarte\, 91010\, United States
CATEGORIES:Jobs
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