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X-WR-CALNAME:Cancer Epigenetics Society
X-ORIGINAL-URL:https://ces.b2sg.org
X-WR-CALDESC:Events for Cancer Epigenetics Society
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TZID:Europe/Paris
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TZOFFSETFROM:+0100
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DTSTART:20180325T010000
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DTSTART:20181028T010000
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DTSTART;VALUE=DATE:20180812
DTEND;VALUE=DATE:20180929
DTSTAMP:20260828T053623
CREATED:20180812T110400Z
LAST-MODIFIED:20180812T110400Z
UID:20463-1534032000-1538179199@ces.b2sg.org
SUMMARY:Faculty Position in Cancer Biology/Genetics
DESCRIPTION:The Life Sciences Institute (LSI) at the University of Michigan invites applications for an open rank faculty position in Cancer Biology/Genetics. Successful candidates will have experience in cancer biology/genetics\, with specific research targets related to cancer metabolism\, cancer genetics/genomics/epigenetics\, chemical biology\, tumor microenvironment\, or tumor immunology. \nFaculty will hold both a Research Professor appointment in the LSI as well as an Assistant\, Associate\, or Full Professor appointment in one of the University’s schools and colleges. Joint appointments are likely in the Medical School\, the College of Literature\, Science\, and the Arts\, the College of Engineering\, the School of Public Health\, the Dental School\, or the College of Pharmacy. All faculty are expected to participate in the University of Michigan’s teaching mission and to demonstrate commitment to service in the larger community. Candidates are expected to develop an internationally recognized program of scholarly research and to excel in teaching and mentoring at the graduate level. \nThe LSI is a scientific enterprise at the University of Michigan dedicated to fundamental discovery in the biological sciences in a state-of-the-art collaborative physical space (www.lsi.umich.edu). Through basic discovery\, the institute seeks to advance knowledge in critical areas of biology with an ultimate goal of contributing to human health including cancer\, metabolic disorders\, brain disorders\, and infectious disease. \nThe LSI is currently home to 22 faculty members in the disciplines of chemistry\, cell biology\, physiology\, genetics\, chemical biology\, biophysics\, structural biology\, and stem cell biology\, including three Howard Hughes Medical Institute investigators and eight members of the National Academies of Medicine or Sciences. Our culture centers on upholding scientific excellence\, embracing risk\, and collaborating across disciplines to achieve an impact greater than the sum of our individual parts. \nIn addition to faculty labs\, the institute houses state-of-the-art instrumentation and computing\, including the following transmission electron microscopes: 300kV Titan Krios\, 200kV Talos Artica\, 120kV Tecnai G2 Spirit\, and 100vK Morgagni. Additional institute resources include high-throughput screening center with extensive chemical collections and a unique library of natural product extracts\, and a comprehensive protein production and X-ray crystallography facility. The LSI is also home to the U-M Program in Chemical Biology. \nApplication materials are due on Friday\, September 28\, 2018. Interested applicants will submit a cover letter\, curriculum vitae\, a summary of future research plans (up to 4 pages)\, contact information for three faculty who will write a letter of recommendation\, and copies of up to three publications on our online application site (lsi.science/2018facultyposting). Individuals from groups historically under-represented in the sciences are strongly encouraged to apply.
URL:https://ces.b2sg.org/event/mi-12aug18/
LOCATION:University of Michigan\, 500 S State St\, Ann Arbor\, MI\, 48109\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180821
DTEND;VALUE=DATE:20180923
DTSTAMP:20260828T053623
CREATED:20180821T064631Z
LAST-MODIFIED:20180821T064631Z
UID:20508-1534809600-1537660799@ces.b2sg.org
SUMMARY:Senior Scientist - Discovery Oncology
DESCRIPTION:We are seeking a highly qualified scientist with a strong background in oncology to join our Discovery Oncology team in Boston. The successful candidate will have a track record of innovative and collaborative research\, demonstrated through peer-reviewed publications. Primary responsibilities will include designing and carrying out experiments in the lab to build and support projects in the early discovery pipeline. An ability to communicate clearly and collaborate effectively with colleagues in the discovery group as well as scientists from different disciplines will be essential.\nThe specific responsibilities of the candidate include but are not limited to:\n\n\nDesign\, conduct\, interpret and report in vitro and cellular oncology studies using a wide range of established methodologies.\nDevelop new methods and protocols where needed.\nEnsure data generated is communicated in a concise\, easy to understand manner to the appropriate teams and stakeholders.\nMonitor\, review and critically interpret published work to guide internal research\nContribute scientifically to oncology drug discovery research programs\, including identification and validation of novel targets.\nCollaborate with members from other functional areas\, including medicinal chemistry\, in vivo and in vitro pharmacology and translational sciences.\nWork with external academic\, biotechnology\, and contract research organizations.\n\n\nQualifications \nEducation Minimum Requirement: PhD in an area relevant to oncology\nRequired Experience and Skills:\n\nA minimum of 1 year of post-doctoral experience in oncology.\nDeep technical and practical experience in cellular models and pathways of cancer.\nCandidate should be a strong team player with excellent oral and written communication skills and with a demonstrated ability to work independently to design experiments\, interpret data\, troubleshoot\, and suggest next steps.\n\n\nPreferred Experience and Skills:\n\nKnowledge of epigenetics\, DNA damage repair and/or immuno-oncology.\nProven record of innovative thinking to propose and champion new ideas and solve problems.\nDemonstrated ability to thrive in a team environment.\nPrior drug discovery experience.\n\n\nYour role at Merck is integral to helping the world meet new breakthroughs that affect generations to come\, and we’re counting on your skills and inventiveness to help make meaningful contributions to global medical advancement. At Merck\, we’re inventing for life.\nIf you need assistance and/or a reasonable accommodation due to a disability during the application or the recruiting process\, please send a request to staffingaadar@merck.com.
URL:https://ces.b2sg.org/event/merck-21aug18/
LOCATION:Merck\, 33 Avenue Louis Pasteur\, Boston\, MA\, 02115\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180822
DTEND;VALUE=DATE:20180924
DTSTAMP:20260828T053623
CREATED:20180822T063546Z
LAST-MODIFIED:20180822T063546Z
UID:20525-1534896000-1537747199@ces.b2sg.org
SUMMARY:Senior Scientist - Epigenetics
DESCRIPTION:We are seeking a highly motivated scientist to join our Epigenetics Center of Excellence. The successful candidate will have a strong foundation in transcription regulation in cancer with previous experience in Drug Discovery. The candidate will be expected to design\, plan and execute biological studies for identifying new targets in various therapeutic areas and to support drug discovery projects from target identification to nomination of development candidates. \nSkills/Knowledge Required \n\nPh.D. in Biology or related scientific discipline with at least 6 years of relevant cancer research experience\, preferably in Industry; Master’s degree with at least 12 years work experience; or\, Bachelor’s degree in a scientific discipline with at least 14 years work experience.\nProficient in cell biology including shRNA and CRISPR technologies\nExperience in target validation\, functional and biomarker cell-based assay development.\nExperience in performing and/or interpreting epigenetic profiling studies is highly desired (DNA methylation\, RNA-sequencing\, ChIP-sequencing and ATAC-sequencing).\nSolid experience in Drug Discovery.\nHighly motivated\, innovative and strong team player. Experience to work in a cross-functional team\nExcellent time management and organizational skill.\nStrong communication skills\, both written and oral.\nStrong ability to work in a fast-paced environment is essential.
URL:https://ces.b2sg.org/event/celgene-22aug18/
LOCATION:Celgene San Diego\, 10300 Campus Point Dr\, San Diego\, CA\, 92121\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180823
DTEND;VALUE=DATE:20180925
DTSTAMP:20260828T053623
CREATED:20180823T063736Z
LAST-MODIFIED:20180823T064245Z
UID:20547-1534982400-1537833599@ces.b2sg.org
SUMMARY:Postdoctoral Research Associate
DESCRIPTION:Department Eppley Inst Research 50000686 Business Unit(College/Institute) Eppley Institute FTE: \n100 \nReg-Temp Full-Time Regular Work Schedule TBD 8-5pm Requisition Category Research – Academic Requisition Title Postdoctoral Research Associate Job Title/Academic Rank Postdoctoral Research Associate Additional Requisition Title Appointment Type A1 – REG OTHER ACAD SAL Salary Range Salary Commensurate with Experience Job/EEO Category Professional Non-Faculty (Includes Other Academic) Job Requisition Begin Date 08/27/2018 \n\n\nPosition Qualification \n\n\nPosition Summary\n\nResearch projects that will involve studies in B-cell malignancies including disease biology\, tumor microenvironment interactions and immune profile as well as pre-clinical evaluation of anti-cancer therapeutics \n\n\n\nRequired Qualifications\n\nCandidates should have PhD in cancer biology\, immunology or related field. Basic and molecular biology techniques required. Experience with mouse studies and cancer immunology is preferred. The candidates should be highly motivated with good oral and written communication skills in English. \n\n\n\nSupplemental Qualifications\n\nflow cytometry\, hematological malignancies and epigenetics.
URL:https://ces.b2sg.org/event/unmc-23aug18/
LOCATION:UNMC University of Nebraska Medical Center\, 42nd and Emile\, Omaha\, NE\, 68198\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180824
DTEND;VALUE=DATE:20180926
DTSTAMP:20260828T053623
CREATED:20180824T054300Z
LAST-MODIFIED:20180824T054300Z
UID:20566-1535068800-1537919999@ces.b2sg.org
SUMMARY:Postdoctoral Research Associates
DESCRIPTION:Multiple Postdoctoral Research Associate positions are immediately available in the laboratory of Dr. Jinghui Zhang\, chair of the Department of Computational Biology. We are seeking highly motivated and creative candidates to lead the discovery and/or methods development in the following areas: a) non-coding driver variants that affect gene regulation in the context of predisposition\, initiation\, and progression of pediatric cancer; b) clonal evolution of relapsed cancer; and c) genomic cloud\, clinical data integration and visualization. The candidates will have access to the large collection of genomic and epigenetic data generated from pediatric cancer patients\, 3D genome technology such as Hi-C/Capture C\, long-read sequencing platform\, and state-of-art visualization tools. The successful candidate will have a strong interest in quantitative data analysis or data visualization with formal training in one of the following areas: genomics\, bioinformatics\, computer science\, genetics\, or cancer biology. Computer programming skills are preferred and interest or experience in genome analysis is a plus. \nSuccessful candidates are expected to excel at critical thinking\, be quick learners for new analytical approaches\, and capable of applying or developing novel computational methods for solving complex problems. Candidates must have a doctoral degree (PhD or MD)\, an excellent publication record\, interest in computational analysis\, and great communication skills. The lab will provide working experience for a fellow who is interested in leading or participating in all aspects of cancer omics studies via multi-disciplinary teamwork. Each fellow will have opportunities to interact with leaders in the fields of pediatric cancer\, epigenetics and translational research within and outside the institution. Inter-disciplinary training will be provided to broaden or strengthen computational or biological expertise. \nInterested applicants are encouraged to apply at https://bit.ly/2NaJdaN \nRecognized as a world leader of genomic research in pediatric cancer\, the Zhang lab has led the characterization of the genomic landscape for over 20 subtypes of pediatric cancers with high-impact publications in Nature\, Nature Genetics\, Nature Methods\, JAMA\, Cancer Cell\, and NEJM in the last five years. The lab has a well-established track record of developing and publishing novel and high-impact analytical and visualization tools for cancer genomic research. Research in the lab is facilitated by access to the wealth of high-quality data\, St. Jude Genomics Cloud\, state-of-art high performance computing facility\, novel analytical pipelines\, latest genomic assay technology\, and scientific expertise in genomics\, cancer biology\, mathematics\, and computer science.
URL:https://ces.b2sg.org/event/stjude-24aug18/
LOCATION:St. Jude Children’s Hospital\, 262 Danny Thomas Pl\, Memphis\, TN\, 38105\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180826
DTEND;VALUE=DATE:20180928
DTSTAMP:20260828T053623
CREATED:20180826T072035Z
LAST-MODIFIED:20180826T072035Z
UID:20577-1535241600-1538092799@ces.b2sg.org
SUMMARY:Postdoctoral Scientist
DESCRIPTION:A Postdoctoral Scientist position is available for a skilled and motivated scientist in the Laboratory of Dr. Maho Shibata in the Department of Anatomy and Cell Biology and the Cancer Center at the George Washington University School of Medicine and Health Sciences. \nDr. Shibata’s lab applies concepts from developmental biology and stem cell biology to prostate cancer research. The lab uses genetically engineered mouse models\, explant cultures\, and 3D organoid culture systems to study androgen signaling during prostate development\, and to identify novel molecular drivers of castration-resistant prostate cancer. There are multiple project possibilities. \nDuties include: \n\nIndependently design experiments\, collect and analyze data\, and assist collaborators\nPresent findings in group meetings and internal and external scientific meetings\nPrepare and submit postdoctoral fellowship applications\nWrite and publish research manuscripts\nSupervise and train students\nPerform other duties as assigned. The omission of specific duties does not preclude the supervisor from assigning duties that are logically related to the position.\n\n\nMinimum Qualifications: \nQualified candidates will hold a PhD in a related discipline. Degree must be conferred by the start date of the position. \nAdditional Required Licenses/Certifications/Posting Specific Minimum Qualifications: Preferred Qualifications: \nPhD experience in one or more of the following: cancer biology\, mouse development\, mouse genetics\, stem cell biology\, epigenetics\, computational biology\nAt least 1 first author peer-reviewed publication
URL:https://ces.b2sg.org/event/gwu-26aug18/
LOCATION:George Washington University\, 2121 I St NW\, Washington\, DC\, 20052\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180902
DTEND;VALUE=DATE:20181004
DTSTAMP:20260828T053623
CREATED:20180902T194432Z
LAST-MODIFIED:20180902T194655Z
UID:20591-1535846400-1538611199@ces.b2sg.org
SUMMARY:Postdoctoral Research Fellow
DESCRIPTION:The Hackensack Meridian Health Center for Discovery and Innovation is offering a position for postdoctoral studies in the field of cancer signaling and gene expression in the laboratory of Dr. Byungwoo Ryu.  The goal of the laboratory’s research program is to unravel the cancer epigenome regulating mechanisms which can be targeted for the sensitization to the precision therapies in the hope of translating these therapeutic modalities to have long-term clinical benefit. The Ryu laboratory focuses on investigating chromatin remodeling enzymes\, such as histone and DNA modifiers and gene transcription factors as potential targets for overcoming the resistance of oncogene-targeting therapies and enhancing the objective therapy response rate of immune check-point blockade therapies.  The Ryu laboratory uses chemical genetics approaches including small molecule inhibitors\, genome/epigenome-wide profiling\, gene-editing technology\, and animal models. Successful postdoctoral candidate will have a strong interest in cancer biology\, epigenetics\, and immuno-oncology.  The candidate will perform in vivo animal models and in vitro analyses. The postdoctoral fellow is expected to understand the project and work independently taking responsibilities in the development and execution of experimental procedures to successfully advance the research project. The successful candidate will be responsible for preparing data for presentations\, progress reports\, and the preparation of manuscripts and posters. The post-doctoral fellow is anticipated to have good communication and writing skills. The successful candidate will have a team-oriented mindset and will provide guidance to junior members. \n  \n\n\n\nResponsibilities\n\n\n\n\nProficient at most gold standard assays in molecular biology and genetics.\nDesign and conduct animal studies using a vast array of genetic models.\nPerform data analysis and interpretation.\nPresent results in internal and external research forums.\nParticipate in grant and manuscript writing\, as appropriate.\n\n\n\n\nQualifications\n\n\n\n\n\nKnowledge\, Education and Skills Required: \n  \n\nHold a Ph.D. in Molecular Biology\, Biochemistry\, Cancer biology or equivalent from an accredited graduate level institution.\nMinimum publication or in preparation of one article as first author in a reputable peer-reviewed scientific journal.\nExcellent analytical and presentation skills.\nExpertise in cell culture\, flow cytometry\, mouse handling\, and basic cellular and molecular biology techniques required.\n\n  \nKnowledge\, Education and Skills Preferred: \n  \n\nKnowledge and experience with RNA/DNA extraction\, PCR and qPCR analysis\, and next generation sequencing/bioinformatics a plus.
URL:https://ces.b2sg.org/event/hmh-2sept18/
LOCATION:Hackensack University Medical Center\, 30 Prospect Ave\, Hackensack\, NJ\, 07601\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180903
DTEND;VALUE=DATE:20181005
DTSTAMP:20260828T053623
CREATED:20180903T104140Z
LAST-MODIFIED:20180903T104215Z
UID:20596-1535932800-1538697599@ces.b2sg.org
SUMMARY:Population Scientist Positions
DESCRIPTION:The University of New Mexico National Cancer Institute (NCI) Designated Comprehensive Cancer Center (UNMCCC) and the Department of Internal Medicine\, Division of Epidemiology\, Biostatistics\, and Preventive Medicine at the UNM School of Medicine are seeking population scientists with expertise in population-based molecular and/or genetic epidemiology to expand programmatic efforts in cancer control and population science in New Mexico. While these are open rank\, tenure track positions\, we seek highly interactive population scientists with active or developing externally funded research programs and a high degree of academic accomplishments. Selected candidates will have the opportunity to work collaboratively across multiple scientific and clinical oncology disciplines. We are particularly seeking epidemiologists in the areas of genomics\, epigenetics\, gene-environment interactions\, and genetic ancestry and genetic risk assessment. Numerous opportunities are available for translating laboratory-based approaches to improvements in screening\, diagnosis and treatment of several cancers for which New Mexican’s suffer significant cancer health disparities\, including cancers of the breast\, gynecologic malignancies\, hematologic malignancies\, and cancers of the gastrointestinal\, hepatobiliary\, and genitourinary systems. Preference will be given to candidates whose research incorporates biological specimens and employs and develops laboratory-based genetic/genomic measures of risk. Experience with collecting and integrating genomics/genetics\, patient electronic health records and population-based research data to address health disparities is highly desirable. The UNMCCC has substantial opportunities for energetic multidisciplinary collaborations in a highly collegial environment with potential for growth; applicants may have a laboratory-based program and may utilize an extensive array of UNMCCC Shared Resources. The UNMCCC also houses or supports many additional registries and resources\, including the NCI SEER New Mexico Tumor Registry\, the New Mexico Human Papillomavirus (HPV) Registry\, and the Center for Native American Environmental Health Equity. The UNMCCC is also a member of the ORIEN National Cancer Precision Medicine Network of NCI Cancer Centers engaged in cancer sequencing\, precision oncology\, data sharing\, cancer clinical trials and collaborative research (http://oriencancer.org/). Significant resources\, including excellent salaries\, comprehensive start-up packages\, and potential for an endowed position\, are available. \n\n\n\n\n\n\nQualifications\n\nMinimum Qualifications: \n\nPhD in epidemiology or a related field\nPostdoctoral training in molecular or genetic epidemiology\nA track record of relevant scholarly achievement\, including peer-reviewed funding and high quality publications focused on cancer\nEligibility to work in the United States\, (this is not a J-1 visa opportunity.)\n\nPreferred Qualifications: \n\nInterest or expertise in cancer disparities research;\nExpertise in primary data collection with human populations;\nLaboratory–based genetic/genomic methods related to cancer in humans;\nAll outstanding candidates applying molecular or genetic epidemiologic methods to the study of cancer will be considered. Successful candidates will have a joint appointment in a UNM School of Medicine Department and the UNMCCC.
URL:https://ces.b2sg.org/event/unm-3sept18/
LOCATION:The University of New Mexico Comprehensive Cancer Center\, 1201 Camino de Salud\, Albuquerque\, NM\, 87106\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180904
DTEND;VALUE=DATE:20181006
DTSTAMP:20260828T053623
CREATED:20180904T085848Z
LAST-MODIFIED:20180904T085848Z
UID:20599-1536019200-1538783999@ces.b2sg.org
SUMMARY:Postdoctoral Fellow
DESCRIPTION:Post Doctoral Fellow positions are available in the laboratory of Dr. Matthew Weitzman\, at the Children’s Hospital of Philadelphia (CHOP) and the University of Pennsylvania (Penn). Our lab is part of the rich scientific environment on the CHOP/Penn campus that includes multiple areas of virology\, immunology\, cancer\, and epigenetics. We are located in the new Colket Translational Research Building as part of the Division of Cancer Pathobiology\, in the Department of Pathology & Laboratory Medicine. The lab is also part of the Center for Childhood Cancer Research (CCCR)\, the Center for Cellular & Molecular Therapeutics (CCMT)\, the Penn Institute for Immunology (IFI)\, the Penn Epigenetics program\, and Penn Center for AIDS Research (CFAR). \nThe lab’s research focuses on virus-host interactions and the use of viruses as model systems to study DNA repair\, signaling\, cell biology\, replication\, innate host defenses and gene delivery. We are interested in virus replication and the resulting cellular responses. We study the intersection of virus and host pathways during infection and how they reveal insights into fundamental cellular mechanisms. We are particularly interested in recognition and processing of viral genomes by DNA repair and APOBEC pathways. We are using virus systems to study signaling\, ubiquitination and degradation\, and transcriptional silencing. Viral model systems include adeno-associated virus (AAV)\, adenovirus (Ad) and herpes simplex virus (HSV). \n\nJob Responsibilities \n\n\nConduct independent scholarly research and develop new methods and protocols\nParticipate in project planning\, recording and evaluation of data\nAcquire technical\, lab management and grant writing skills\nParticipate in seminars\, lectures\, poster sessions and presentation at national meetings\nSupervise junior lab members\nAssist with other research projects\n\n\nRequired Education and Experience \n\n\nA terminal degree PhD\, MD\, DVM\, etc.\nAccording to the CMS (Centers for Medicaid and Medicare Services) a copy of diploma or transcript is required as proof of academic achievement for all non-laboratory personnel performing non-waived POC testing\n\n\nPreferred Education\, Experience & Cert/Lic \n\nThe successful applicant will become part of a highly interactive and collaborative team. Applicants must have a Doctoral degree in a related discipline with good skills in molecular biology\, biochemistry and cell biology\, and a strong motivation to learn new techniques and research topics. A background in virology and/or DNA repair would be advantageous. It is expected that this individual will conduct independent scholarly research\, and will contribute to the overall research goals of the project and the research group.
URL:https://ces.b2sg.org/event/chop-4sept18/
LOCATION:Children’s Hospital of Philadelphia\, 3401 Civic Center Blvd\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180905
DTEND;VALUE=DATE:20181007
DTSTAMP:20260828T053623
CREATED:20180905T071551Z
LAST-MODIFIED:20180905T071551Z
UID:20601-1536105600-1538870399@ces.b2sg.org
SUMMARY:Postdoctoral Researcher
DESCRIPTION:The Chandrasekharan Laboratory\, in the Department of Radiation Oncology at the University of Utah and Huntsman Cancer Institute\, is searching for a highly motivated and hardworking postdoctoral researcher with prior experience in gene transcription or genome stability and epigenetic mechanisms\, and the use of genomics-bioinformatics methodologies and mammalian experimental systems (cell culture and mouse model). The Chandrasekharan laboratory is focused on understanding epigenetic histone modifying mechanisms. We are seeking a post-doc to study the regulation and functions of histone modifying enzymes and their potential therapeutic targeting in cancers.\nExperimental duties include\, but are not limited to: creating knockout or knockin cell lines using CRISPR genome-editing technology; performing functional genomics or proteomics experiments and use bioinformatics for data analyses; overexpressing and purifying proteins or protein complexes using chromatography for proteomic\, structural and/or biochemical/biophysical characterization studies; evaluating histone modifying enzyme functions in vivo in genetic mouse models; and performing preclinical drug-dosing studies in cell culture and in xenograft mouse models\nPlease see specific research projects and additional information pertaining to lab research on our website at:\nhttp://healthcare.utah.edu/huntsmancancerinstitute/research/labs/chandrasekharan/ \nResponsibilities \nThe preferred candidate should have a Ph.D. in biomedical sciences\, molecular-cell biology\, or an allied area. Previous laboratory experience in mammalian cell culture and mouse model system\, chromatography\, genome editing\, genomics and bioinformatics are required. The applicant should have a good working knowledge of protein biochemistry\, epigenetics and chromatin biology\, as well as bioinformatics and scientific writing skills. The ideal candidate will have demonstrated initiative\, curiosity and dedication to scientific research as well as the ability to work independently and in a team environment. Essential Functions\n1. Create CRISPR-based knockin or knockout cell lines; perform epigenomics and bioinformatics\, and conduct preclinical studies using in vitro or in vivo mammalian model systems.\n2. Performs and directs specialized and complex lab tests\, experiments and surgical procedures for studies.\n2. Assists the Principal Investigator in the design\, implementation and performance of new protocols and procedures as well as the modification of existing techniques.\n3. Reviews scientific journals\, abstracts and other literature for information concerning experimental procedures.\n4. Makes advanced statistical calculations\, analyzes data and prepares reports summarizing research results.\n5. Operates complex and highly specialized laboratory and surgical instruments and equipment. Instructs others in their use.\n6. Maintains an inventory of supplies\, reagents\, and samples used in procedures for the lab.\n7. May supervise\, train and review the work of laboratory personnel.\n8. May prepare equipment and rooms for studies.\n9. May assist with preparing grant proposals and budgets.\nProblem Solving\nIncumbents in this position work independently to review\, analyze and interpret the results of the data collected and assist the principal investigator in getting the information presented to peers and published in appropriate journals. Incumbents in this position are responsible for addressing unusual or sensitive situations and for bringing them to resolution. If they are unable to bring them to resolution\, they will consult with the principal investigator to obtain resolution. \nThis job description has been designed to indicate the general nature and level of work performed by employees within this classification. It is not designed to contain or be interpreted as a comprehensive inventory of all duties\, responsibilities and qualifications required of employees assigned to the job. \nMinimum Qualifications Preferences \nLooking for a recent graduate with 0-1 year experience. Individuals from historically underrepresented groups\, such as minorities\, women\, qualified persons with disabilities\, and protected veterans are strongly encouraged to apply.
URL:https://ces.b2sg.org/event/ut-5sept18/
LOCATION:University of Utah\, 201 Presidents Cir\, Salt Lake City\, 84112\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180906
DTEND;VALUE=DATE:20181008
DTSTAMP:20260828T053623
CREATED:20180906T114918Z
LAST-MODIFIED:20180906T114918Z
UID:20603-1536192000-1538956799@ces.b2sg.org
SUMMARY:Postdoctoral Research Associate
DESCRIPTION:A postdoctoral scholar position in the areas of genomics\, stem cell biology\, and leukemia is available in the laboratory of Dr. Grant Challen at Washington University School of Medicine in St. Louis. The Challen lab studies the epigenetic regulation of normal and malignant hematopoiesis. The successful applicant will be responsible for characterizing the roles of epigenetics in stem cell differentiation and blood cancer transformation. Our lab uses a variety of cutting edge technologies coupled with traditional cell culture\, molecular biology and mouse genetic models. The Hematopoietic Development and Malignancy (HDMP) program of the Siteman Cancer Center at Washington University in St. Louis provides us access to a variety of specialized research cores to facilitate our projects. Motivated candidates with a PhD or MD with a strong background in molecular and cellular biology\, cancer research and epigenetics are encouraged to apply. For the latest updates about our lab research\, please visit our lab website (www.challenlab.com) and lab Twitter feed (@challenlab). \n  \nPRIMARY DUTIES & RESPONSIBILITIES: \n\nDesign\, plan\, execute and interpret complex experiments integrating cell culture\, mouse models\, and genome sequencing data.\nAbility to independently generate testable hypotheses.\nIntegrated analysis of molecular data.\nAnalyze and interpret results to communicate with others and produce presentations and scientific publications is required.\nAssist in grant preparation and reporting.\nMaintain conformity with ethical standards in research.\nMaintain compliance with good laboratory practice including the maintenance of adequate research records\nCollegial conduct towards co-trainees\, staff members and members of the research group.\n\n\n\n\n\n\n\n\nRequired Qualifications\n\n\n\n\n\n\n\nThe appointee has earned a Ph.D.\, M.D. or equivalent terminal or doctoral degree. \n\n\n\n\n\n\n\n\nPreferred Qualifications\n\n\n\n\n\n\n\n\nApplicants should have a graduate degree in developmental biology\, genetics\, or related field.\nPrevious experience with mouse models\, flow cytometry\, cancer genomics\, and next-generation sequencing applications would be an advantage but is not essential.\nThe successful candidate will be self-motivated\, eager to acquire new knowledge and skills on a regular basis\, and must demonstrate critical thinking skills.\nThe ability to analyze and interpret results to communicate with others and produce scientific publications is required.
URL:https://ces.b2sg.org/event/wu-6sep18/
LOCATION:Washington University School of Medicine in St. Louis\, 660 S Euclid Ave\, St. Louis\, MO\, 63110\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180908
DTEND;VALUE=DATE:20181010
DTSTAMP:20260828T053623
CREATED:20180908T142355Z
LAST-MODIFIED:20180908T142355Z
UID:20607-1536364800-1539129599@ces.b2sg.org
SUMMARY:Post Doctoral Associate
DESCRIPTION:Seeking a highly motivated\, organized\, and responsible individual to lead a major component of our new cancer genetics and epigenetics lab\, as a foundation for their career advancement in academia or industry. Candidates will leverage cancer genomics and epigenomics data that we have generated in a variety of pediatric and adult brain tumors to undertake experiments in functional discovery\, validation\, as well as the development of integrated large-scale datasets using new genetic technologies. The ideal candidate will demonstrate a willingness to learn new concepts and technical skills\, but most importantly harbor an enthusiasm for working in a team-based environment and interfacing with national and international collaborative efforts. \n\nDesigns and conducts laboratory research experiments.\nDocuments\, interprets\, and presents results of experiments and reports to principal investigators.\nCollects\, compiles and analyses data; maintains records.\nWrites manuscripts for scientific publication\nWorks with maintaining mice\, performing procedures related to their project.\nUtilizes advanced computer programs with guidance.\nTrains less experienced members of the lab and assisting with technical procedures\n\nRequired: Doctoral degree with experience related to responsibilities/duties. Candidates more than 3 years from receiving their PhD will not be considered. An ideal candidate will have a strong foundation in molecular biology based techniques\, experience with animal handling and procedures\, and have a willingness to learn/work with complex computational software (R\, unix\, python\, perl).
URL:https://ces.b2sg.org/event/baylor-8sept18/
LOCATION:Baylor College of Medicine\, 1 Baylor Plaza\, Houston\, TX\, 77030\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180909
DTEND;VALUE=DATE:20181011
DTSTAMP:20260828T053623
CREATED:20180909T114433Z
LAST-MODIFIED:20180909T114433Z
UID:20609-1536451200-1539215999@ces.b2sg.org
SUMMARY:Research Fellow
DESCRIPTION:The laboratory of Professor Xiaole Shirley Liu (http://liulab.dfci.harvard.edu/) at Dana-Farber Cancer Institute and Harvard T.H.Chan School of Public Health invites applicants for a computational biology postdoctoral position. The research in the laboratory focuses on designing bioinformatics algorithms and integrative genomics approaches to model gene regulation\, find novel drug targets and combinations\, and predict response to targeted and immunotherapies in cancer. Recently Dr. Liu became the PI of the NCI Cancer Immunologic Data Commons (CIDC) Center to develop the bioinformatics algorithms and infrastructure to integrate comprehensive profiling of all NCI-sponsored immunoncology trials\, with the goal of predicting cancer immunotherapy outcomes. \n\nQualifications\n\n\n\nIdeal applicant should have:\n\nA PhD degree in related field (bioinformatics\, physics\, statistics\, engineering\, etc) received in the last 3 years\nStrong quantitative background (machine learning\, Bayesian inference\, etc.) or computational genomics experiences (high throughput sequence analysis\, etc.)\nStrong programming skills: ((Python | C | C++ | Java) & R)\nAt least two first authored English papers (or three if co-first authors) with submitted\, accepted or published status in journals\nGood spoken and written communication skills in English\n\nInterested applicants should submit CV\, a letter of interest with a one-page proposal for a project to be conducted in the Liu Lab\, and contact of three references to xsliu@jimmy.harvard.edu with subject line “Postdoctoral application”.
URL:https://ces.b2sg.org/event/df-9sept18/
LOCATION:Dana-Farber Cancer Institute\, 450 Brookline Avenue\, Boston\, MA\, 02215\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180910
DTEND;VALUE=DATE:20181012
DTSTAMP:20260828T053623
CREATED:20180910T072448Z
LAST-MODIFIED:20180910T072448Z
UID:20611-1536537600-1539302399@ces.b2sg.org
SUMMARY:Associate/Full Professor
DESCRIPTION:The Department of Nutritional Sciences invites applications for a 9 month\, tenure eligible\, full salaried Associate/Full Professor position supporting the Precision Wellness Initiative in emerging areas at the University of Arizona\, including aging\, brain (cognitive) health\, and inflammatory/metabolic diseases. The position’s duties will consist of 80% research and 20% instruction. \nThe revolutions in genomic\, epigenomic\, metabolomic\, imaging\, information\, and data science technologies have provided extraordinary opportunities to advance population wellness and optimize treatments\, lifestyles and preventives for individuals. The Precision Wellness Initiative at the University of Arizona is designed to enhance research\, education training\, and service programs that use these advanced tools\, and technologies to discover how genetics\, lifestyle and environmental factors (such as diet\, social factors and exercise) impact individual health. The ultimate goal of this Initiative is to discover and impart novel data-driven approaches and competences to personalize human disease prevention thereby promoting wellness throughout the human life span. \nResearch: Candidates for this position are expected to have research experience and interests in precision nutrition and health as it relates to aging\, brain health\, or inflammatory/metabolic diseases. They are also expected to have a strong background and expertise in data-driven science with a special emphasis on omics-based translational research. Candidate qualifications include a Ph.D. degree in nutrition science\, genetics\, genomics\, physiology\, pharmacology\, or cellular/molecular medicine or a related discipline\, high research productivity\, a record of success in obtaining external funding\, experienced teaching in omics-based technologies\, precision nutrition/wellness and/or precision health. Additional research strengths and skills considered include:\n– research experience developing nutritional and preventive interventions\, prognostic indicators\, and physiologic/structural/behavioral in vivo measurement systems for human diseases\n– research experience on the effect of nutritional/lifestyle in preserving brain health\, cognitive function and maintaining neuroplasticity thereby impacting the progression of aging and enhancing healthy aging.\n– research experience in planning and implementation of integrative projects analyzing data from large-scale studies and model systems designed to examine the genetics\, proteomics\, and metabolomics of human diseases\n– experience in scientific leadership roles within multi-disciplinary groups conducting clinical trials and/or observational studies\n– sophisticated knowledge of and experience using public and proprietary bioinformatic databases for annotation of multi-dimensional results leading to inference on factors and processes acting in disease pathogenesis or pathophysiology\n– experience in analysis of large-scale data sets integrating findings on genetic and epigenetic variation with those on environmental/lifestyle factors that may act as effect modifiers or disease predictors/correlates\n– familiarity with emerging applications of machine learning/computational modeling techniques \n\nTeaching: Contribute to the undergraduate and graduate curriculum in following areas: precision health; omics-based translational research including nutrigenomics/nutrigenetics; inflammation\, and metabolism; natural history\, etiology\, pathogenesis and pathophysiology of age-related and inflammatory/metabolic diseases; natural bioactives; development of new undergraduate and graduate programs in precision health and disease prevention; other teaching according to expertise and need. Additionally\, the candidate will be expected to: \n– Establish and maintain an externally-funded and internationally-recognized research program in precision health/nutrition for health promotion and disease prevention. The program is expected to be interdisciplinary and build upon existing collaborations across colleges and centers of excellence.\n– Maintain a strong\, peer-reviewed publication record.\n– Mentor graduate students in the department of Nutritional Sciences.\n– Participate in the instruction of upper level undergraduate and/or graduate courses.\n– Serve on department\, college and university level committees as required
URL:https://ces.b2sg.org/event/az-10sept18/
LOCATION:University of Arizona\, Tuscon\, AZ\, 85721\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180911
DTEND;VALUE=DATE:20181013
DTSTAMP:20260828T053623
CREATED:20180911T084302Z
LAST-MODIFIED:20180911T084302Z
UID:20614-1536624000-1539388799@ces.b2sg.org
SUMMARY:Research Associate I
DESCRIPTION:The Buck Institute for Research on Aging is seeking a Research Associate Iin the Kennedy Laboratory. The Buck Institute is the only independent institute in the U.S. devoted solely to research on aging and age-related diseases such as Alzheimer’s\, Parkinson’s\, cancer\, arthritis\, diabetes\, and stroke. Our mission is to increase the healthspan\, the healthy years of life. Awarded a federal grant to establish interdisciplinary research in a new field called Geroscience\, Buck scientists work in a unique\, collaborative environment allowing them to initiate studies quickly and respond to new opportunities in fields such as stem cell research and regenerative medicine. Our scientists represent a variety of complementary fields\, including genetics\, epigenetics\, biochemistry\, molecular biology\, bioenergetics\, age-associated disease; and technological disciplines such as genomics\, proteomics\, protein interaction networks and bio-informatics. \nThe Buck Institute\, designed by world famous architect I.M. Pei\, is located in Novato\, California\, 25 miles north of the Golden Gate Bridge. \nPOSITION SUMMARY: \nThe Kennedy lab is focused on identifying conserved genes and genetic pathways involved in modulating aging. Scientists in the group use invertebrate model organisms such as yeast and C. elegans to identify genes modulating aging and candidate mechanisms by which they act. These approaches lead to hypotheses that can be tested in mice. The ultimate goal is to understand the aging process in humans and to develop approaches to mitigate age-associated diseases. We are seeking a Research Assistant to drive yeast projects within the lab. \nKEY RESPONSIBILITIES: \n\nDrive the progress of yeast research: replicative lifespan dissection of yeast and organization of strains and basic manipulations.\nBack up laboratory members with regard to: experiments\, documentation of experimental results including data entry and other data management tasks\, analysis and interpretation and reporting of results where necessary\, under the guidance of the PI\, director of the lab or postdoctoral fellows.\nHandle administrative duties that enable the smooth operation of the lab\, including but not limited to: preparing liquid and plate media and common buffers / solutions; aiding in lab organization; ordering supplies; participating in the general care and maintenance of equipment; obtaining environmental safety approvals; and assisting in recruitment efforts of future lab members.\nPerform other duties as assigned.\n\nEDUCATION: \n\nBA/BS in genetics\, biology or related science and knowledge of\, or experience with\, the basic techniques or methods required by the position; or an equivalent combination of education and experience.\nProficient with basic molecular biology\, cell biology\, and protein chemistry laboratory techniques; experience with mammalian cells and tissues\, preferred.\nExcellent ability to communicate analyses orally & in writing; excellent organizational skills & record keeping; proficiency in MS Word/Excel/PowerPoint.\n\nEXPERIENCE: \n\nGenerally requires a minimum of 0-2 years’ experience with a Bachelor’s degree.
URL:https://ces.b2sg.org/event/buck-11sept18/
LOCATION:Buck Institute\, 8001 Redwood Boulevard\, Novato\, CA\, 94945\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180912
DTEND;VALUE=DATE:20181014
DTSTAMP:20260828T053623
CREATED:20180912T060552Z
LAST-MODIFIED:20180912T060552Z
UID:20616-1536710400-1539475199@ces.b2sg.org
SUMMARY:Research Assistant Professor
DESCRIPTION:The School of Biological Sciences\, University of Nebraska\, Lincoln\, NE\, USA\, seeks applications for a Research Assistant Professor to work on bioinformatics or computational biology\, genomics\, epigenetics\, omics-data integration\, etc. \nThe successful candidate will conduct the research on diverse projects in Dr. Chi Zhang’s Lab\, including bioinformatics tool development\, high-throughput data analysis\, and data integration. The candidate will also be responsible for lab management and assisting in the supervision of postdocs\, graduate students\, undergraduate students\, developing new areas of research\, and writing publications and grant proposals. Appointment is for three years with a possibility of further extension. \nMinimum Required Qualifications \n\nPhD degree in Bioinformatics\, Genomics\, Biological Sciences\, Biochemistry\, Biostatistics\, Physics\, or related fields.\n\n\nPractical experience of next-generation sequencing data analysis\, computational systems biology and data integration\, and solid knowledge in genomics\, gene expression/regulation and biological networks.\n\n\nProven skills in programming (such as Perl and R)\, experience with Linux/Unix environments and algorithm design.\n\n\nSolid background and knowledge in artificial intelligence (AI) and its application of biological data.\n\n\nSelf-motivated with excellent communication skills and an ability to work well in a team environment.\n\n\nAt least 7yr working experience in bioinformatics and/or computational biology.\n\nPreferred Qualifications \n\nEducation in computer science.\n\n\nBackground in both molecular biology and computer science.\n\n\nExperience in disease\, especially cancer\, related biological data analysis and/or plant genomics/genetics/epigenetics data analysis.
URL:https://ces.b2sg.org/event/neb-12sept18/
LOCATION:University of Nebraska\, 1400 R Street\, Lincoln\, NE\, 68588\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180914
DTEND;VALUE=DATE:20181016
DTSTAMP:20260828T053623
CREATED:20180914T094858Z
LAST-MODIFIED:20180914T094957Z
UID:20620-1536883200-1539647999@ces.b2sg.org
SUMMARY:Assistant Professor of Cancer Biology
DESCRIPTION:The Department of Cancer Biology at the Perelman School of Medicine at the University of Pennsylvania seeks candidates for an Assistant Professor position in the tenure track. The successful applicant will have experience in the field of cancer biology\, including cancer genetics and proteomics\, cancer cell biology\, tumor microenvironment\, cancer stem cells\, metastasis\, tumor immunology\, chemical biology\, cancer metabolism\, oncogenic signal transduction pathways\, genome integrity\, cancer epigenetics\, and cancer-related systems biology and bioinformatics. Responsibilities include establishment and maintenance of an externally funded independent research program\, as well as teaching and mentoring of students. Applicants must have an Ph.D. and/or M.D. degree and have demonstrated excellent qualifications in education and research. \nWe seek candidates who embrace and reflect diversity in the broadest sense. \nThe University of Pennsylvania is an EOE. Minorities/Women/Individuals with disabilities/Protected Veterans are encouraged to apply. \n\nApply for this position online at:  \nhttps://www.med.upenn.edu/apps/faculty_ad/index.php/g/d5157
URL:https://ces.b2sg.org/event/ibi-14sept18/
LOCATION:University of Pennsylvania\, 3400 Civic Center Blvd\, Philadelphia\, 19104\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180916
DTEND;VALUE=DATE:20180922
DTSTAMP:20260828T053623
CREATED:20180502T183132Z
LAST-MODIFIED:20180503T123424Z
UID:19979-1537056000-1537574399@ces.b2sg.org
SUMMARY:Transcription\, Chromatin and Epigenetics
DESCRIPTION:This FASEB SRC is designed to highlight the major advances in science and integrate different topics\, which are part of an extremely fast-moving and exciting field of research. The biological scope and the mechanisms of action of DNA and RNA molecules\, which have roles in dosage compensation\, imprinting\, enhancer function and transcriptional regulation\, have a great impact in health and diseases\, including aging and cancer.\nA key reason for the increasing interest in chromatin and transcription is the appreciation that regulation of chromatin organization and transcription is the fundamental cornerstone for establishing gene expression patterns that determine cell state and fate.  Researchers studying embryonic stem cells\, organism development\, diseases (e.g. cancer) have discovered a common interest in elucidating the mechanisms that govern gene expression. Moreover\, there has been a recent explosion of activity in the fields of RNA epigenetics and non-coding RNAs\, which have become integral parts of the field of gene expression. This five-day conference will gather confirmed and junior scientists from academia\, biotech\, pharma and clinical settings to share ideas and concepts\, and create synergy in the following domains: \n\ntranscription and chromatin in gene regulation\,\nchromatin complexes\,\nDNA and RNA modifications\,\nnon-coding RNAs\,\nstem cells\, aging and cancer.\n\nAs epigenomic is the emerging tool for studying complex diseases\, this conference will highlight the latest technologies and methodologies for studying biological modifications in cells\, tissues and organisms and should attract a lot of attention. Indeed\, researchers nowadays work on comprehensive\, genome-wide datasets across multiple domains and need to be supported by sophisticated technologies. Experts from academia and industry will present their most recent technological developments in different areas of research. This SRC will also highlight “epitranscriptomics” and should attract a whole range of researchers curious to learn the latest advances in this booming area of epigenetics. Scientists using diverse approaches such as molecular biology\, cell biology genetics\, epigenomics\, and biochemistry will come together to discuss their state-of-the-art discoveries. This SRC series has historically brought together scientists involved with diverse systems and strategies\, resulting in exciting and synergistic discussions. 2018 will continue to fulfill this role as a forum for the most advanced science in transcription\, chromatin and epigenetics. Together with junior and leader speakers\, additional oral presentations will be selected from submitted abstracts and there will be opportunity for dynamic and interactive evening poster presentations. Social and recreational activities will provide all registrants an opportunity to mix with senior scientists.  Vibrant interactions between established and young investigators at Meet-the-expert sessions\, poster sessions\, meals\, and social activities provide an ideal opportunity for attendees to meet\, discuss\, and develop new collaborations. \nImportant Deadlines: \n\nEarly bird registration deadline July 23\, 2018\nLast day to register August 2\, 2018\n\nHighlights\n\nWorkshop topics: Career in academia\, career in industry\, grant writing and publication process talks given by experts\nRound table discussions with Experts; poster sessions with light refreshments; social activities\nCompany presentations: latest technologies/product development/new areas of interest/published papers\n\nKeynote Speaker\nDanny Reinberg\nNYU School of Medicine \nConference Organizers\nFrançois Fuks\nUniversity of Brussels\, Belgium\nffuks@ulb.ac.be \nAnne Brunet\nStanford University\nanne.brunet@stanford.edu \nFASEB Conference Staff\nRobin Crawford\, CMP\, Conference Manager \nContact us\nEmail: src@faseb.org\nPhone: 1.301.634.7010 \n 
URL:https://ces.b2sg.org/event/faseb-16sept18/
LOCATION:Hilton Metropole Florence\, Via del Cavallaccio 36\, Florence\, 50142\, Italy
CATEGORIES:Meetings
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180916
DTEND;VALUE=DATE:20181018
DTSTAMP:20260828T053623
CREATED:20180916T161801Z
LAST-MODIFIED:20180916T161801Z
UID:20644-1537056000-1539820799@ces.b2sg.org
SUMMARY:Postdoctoral Fellow
DESCRIPTION:A Postdoctoral position in Hematopoietic Stem Cell Biology is available in the laboratory of Peter Kurre\, M.D.\, at the Comprehensive Center for Bone Marrow Failure. The Laboratory has longstanding expertise in Hematopoietic stem cell biology\, including the development of preclinical approaches to Hematopoietic Stem Cell Gene Therapy. Ongoing work is focused on the development and refinement of anchoring lentivector designs with reduced propensity for genomic integration and mutagenicity. In a rapidly growing area of science\, investigations will involve a wide range of methods in virology\, vectorology\, cell-\, molecular biology imaging and bioinformatics tools. The postdoctoral fellow will\, under the direction/guidance of a mentor Dr. Mortimer Poncz\, assume responsibility for a specific\, on-going research project. \n\nThe successful candidate will be highly motivated and creative. Excellent verbal and written communication skills are critical. Scrupulous attention to detail\, good record keeping\, the ability to work independently\, in an expanding dynamic workgroup are essential. Candidates must have a recent Ph.D.\, D.V.M\, or M.D./Ph.D. in the biological sciences. Experience with mammalian cell culture (established cell lines and primary leukemia samples)\, molecular and cell biology techniques\, flow-cytometry\, and mouse models are desirable. The position is funded by NIH funds and private grants and by the The Children’s Hospital of Philadelphia\, with an understanding that the applicant will compete for trainee funding as part of their own career development. \n\nThe successful candidate will thrive in a multi-disciplinary\, collaborative team to extend\, refine and enhance skills necessary for professional and career development\, and broaden his/her scientific background by acquiring new research capabilities. It is expected that this individual will conduct independent scholarly research\, and will contribute directly to the overall research goals of the project and the research group. Postdocs will participate in project planning\, recording and interpretation/evaluation of data\, and communication of results. The candidate will acquire critical technical and lab management skills for their own career\, and to be proficient at manuscript/grant writing; postdocs will participate in seminars\, lectures\, poster sessions and presentations at national meetings. Postdoctoral fellows also will participate in the supervision of junior lab members\, develop new methods and protocols for research\, and assist with the development of other research projects in the lab. \nPostdoctoral fellows at The Children’s Hospital of Philadelphia receive mentored training in a premier scientific and collaborative environment that includes the resources of the adjacent University of Pennsylvania. \n\nTo learn more about the CHOP Research Institute and the research programs visit: http://research.chop.edu. \nJob Responsibilities \n\nConduct independent scholarly research and develop new methods and protocols\nParticipate in project planning\, recording and evaluation of data\nAcquire technical\, lab management and grant writing skills\nParticipate in seminars\, lectures\, poster sessions and presentation at national meetings\nSupervise junior lab members\nAssist with other research projects\n\nRequired Education and Experience \n\nA terminal degree PhD\, MD\, DVM\, etc.\nAccording to the CMS (Centers for Medicaid and Medicare Services) a copy of diploma or transcript is required as proof of academic achievement for all non-laboratory personnel performing non-waived POC testing
URL:https://ces.b2sg.org/event/chop-16sept18/
LOCATION:Children’s Hospital of Philadelphia\, 3401 Civic Center Blvd\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180917
DTEND;VALUE=DATE:20181019
DTSTAMP:20260828T053623
CREATED:20180917T055323Z
LAST-MODIFIED:20180917T055323Z
UID:20646-1537142400-1539907199@ces.b2sg.org
SUMMARY:Postdoctoral Associate
DESCRIPTION:A postdoctoral associate position is available in the laboratory of Dr. Jennifer Trowbridge at The Jackson Laboratory in Bar Harbor\, Maine\, to study epigenetic mechanisms governing hematopoietic stem cell lineage commitment and how deregulation of epigenetic modifications leads to myeloproliferative disorders including leukemia. The Trowbridge Lab offers a challenging but supportive environment. Past trainees have a noteworthy track record for obtaining grant funding and fellowships. For more information\, please visit: https://trowbridgelab.com.\n\n\n\nResponsibilities\n\n\n\nThe successful candidate will be able to plan\, develop\, execute\, and analyze an independent research project. \n\n\n\nQualifications\n\n\n\n\nM.D. or Ph.D. in biological or related sciences is required.\nStrong training background in molecular biology\, cell biology\, and/or epigenetics/epigenomics is preferred.\nOther areas of experience/training include stem cell biology\, immunology\, cancer biology\, or developmental biology.\nExceptional verbal and written communication skills;\nSelf-motivated and career-oriented individual preferred;\nExperience in flow cytometry and work with mouse models;\nMinimum of one 1st author paper from graduate work.\n\nTo apply\, a complete application must include a cover letter describing past research accomplishments\, research interests\, and career aspirations; a current CV; and the names of three references.
URL:https://ces.b2sg.org/event/jl-17sept18/
LOCATION:Jackson Laboratory\, 600 Main Street\, Bar Harbor\, ME\, 04609\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180918
DTEND;VALUE=DATE:20181020
DTSTAMP:20260828T053623
CREATED:20180918T171857Z
LAST-MODIFIED:20180918T172235Z
UID:20679-1537228800-1539993599@ces.b2sg.org
SUMMARY:Research Scientist - T Cell Metabolism
DESCRIPTION:Poseida Therapeutics\, Inc. is seeking an outstanding candidate to join our immuno-oncology team at La Jolla\, San Diego\, CA. The T Cell Metabolism Scientist will design and perform experiments optimizing the manufacture of chimeric antigen receptor (CAR)-T cell therapies of the T stem cell memory subset (TSCM)\, which are an ideal cell population for adoptive immunotherapy since they are long-lived\, self-renewing and multi-potent. The hypothetical attributes of a CAR-T product with a high percentage of TSCM include enhanced durability\, as well as potency against solid tumors. Investigation will focus on immunometabolism for understanding and optimizing the non-viral piggyBac™ CAR-Tscm manufacturing process via the use of in vitro human cell-based assays assessing T cell proliferation\, phenotype and function. The position will play a critical role in the evaluation and identification of manufacturing strategies for enhancing metabolic fitness and bioenergetic profile of CAR-T products.  The successful candidate will demonstrate excellent oral and written communication skills\, work well both independently and as part of a team\, and be able to work on multiple projects/product candidates simultaneously.  Broad expertise in cellular metabolism\, key regulatory pathways\, T cell culture\, and flow cytometry is required for this role.  The position is a hands-on\, laboratory-based role with the possibility of direct reports. \nPoseida Therapeutics is translating best-in-class gene engineering technologies into lifesaving cell therapies. The company is developing CAR T-cell immunotherapies for multiple myeloma\, prostate and other cancer types\, as well as gene therapies for orphan diseases. P-BCMA-101 is Poseida’s lead CAR-T therapy currently in Phase 1 clinical development for the treatment of multiple myeloma. Poseida has assembled a suite of industry-leading gene engineering technologies\, including the piggyBac™ DNA Modification System\, TAL-CLOVER™ and Cas-CLOVER™ site-specific nucleases\, and Footprint-Free™ Gene Editing (FFGE). For more information\, visit www.poseida.com. \nQualifications\nRequired Experience and Skills: \n\nPhD or equivalent in cell biology\, immunology\, or related field\nExpertise in metabolic pathways supporting T cell proliferation and differentiation (glycolysis\, fatty acid\, mitochondrial metabolism\, etc.)\nA detailed knowledge of lipid metabolism and salvage pathways used in nutrient-limiting\, solid tumor microenvironments\nUnderstanding of key T cell regulatory and differentiation pathways (PI3K-Akt-mTOR pathway in differentiation and memory formation\, etc.)\nExperience in the characterization\, culture\, expansion\, and manipulation of T cells\nAssessment of mitochondrial mass\, activity\, and spare respiratory capacity (Seahorse XF\, etc.)\nKnowledge of cellular and/or tumor immunology principles\, technologies\, and experimental techniques (cell culture\, in vitro cellular assays\, flow cytometry\, etc.)\nMulti-parameter flow cytometry and proficiency in FACS data analysis programs\nExperience designing\, executing\, and interpreting genomics and transcriptome assays (NGS\, RNA-Seq\, Single Cell RNA-Seq\, AmpliSeq\, etc.)\nCell separation technologies (e.g.\, Miltenyi AutoMACS) and FACS sorting\nAbility to organize\, communicate\, and present complex data sets to key stakeholders from diverse backgrounds\nExcellent oral and communication skills\n\nPreferred Experience and Skills: \n\nUnderstanding of epigenetic control of T cell differentiation\nExperience developing\, testing\, and/or utilizing CAR-T products\nFunctional assays measuring cellular activation\, cytokine release\, proliferation\, and killing\nWork with external academic\, biotechnology\, and contract research organizations
URL:https://ces.b2sg.org/event/poseida-18sept18/
LOCATION:Poseida Therapeutics\, 4242 Campus Point Court\, Suite 700\, San Diego\, CA\, 92121\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180919
DTEND;VALUE=DATE:20181021
DTSTAMP:20260828T053623
CREATED:20180919T070406Z
LAST-MODIFIED:20180919T070406Z
UID:20684-1537315200-1540079999@ces.b2sg.org
SUMMARY:Postdoctoral Fellow
DESCRIPTION:A post-doctoral position is available in Dr. Carol J. Thiele’s laboratory in the Cell & Molecular Biology Section in the Pediatric Oncology Branch at the NCI to study mechanisms of epigenetic dysregulation in pediatric neuroectodermal tumors. The broad goal of the laboratory is to study mechanisms of differentiation and how they are dysregulated in embryonal cancers with an eye towards developing novel therapeutic strategies based on an understanding of tumor biology. We use state-of-the-art screening strategies to identify key regulators of growth and differentiation. Current projects are mechanisms of regulation of EZH2 in neuroblastoma\, mESC reprogramming by tumor suppressors\, mechanisms of retinoid regulation of superenhancers\, regulation of tumor cell plasticity and mechanisms of epigenetic dysregulation in pediatric tumors. \n\n\n\n\nNumber of Positions:\n\n1\n\n\n\nC.V. Required:\n\nYes\n\n\n\nNumber of References Required:\n\n3\n\n\n\nBibliography Required:\n\nYes\n\n\n\nExperience Required:\n\n\nThe successful candidate should have a PhD in genetics/molecular biology/biochemistry/cell biology with less than 2 years of post-doctoral experience. Individuals with a strong background in molecular biology and experience in chromatin biology are encouraged to apply. Experience in genome-wide assays\, bioinformatics or deep sequencing is an additional asset. Qualified candidates should have strong communication skills\, and a demonstrated record of scientific achievement through peer-reviewed publications. Successful\, well-motivated candidates will join a multi-disciplinary team of researchers working in a basic/clinical translation environment. \n\n\n\n\nHow To Apply:\n\n\nInterested individuals should send a statement of research interests\, a curriculum vitae and bibliography and 3 letters of recommendation to Carol Thiele. \n\n\n\n\nContact Name:\n\nCarol Thiele\n\n\n\nContact E-mail:\n\nct47a@nih.gov\n\n\n\nContact Phone:\n\n240-858-3849
URL:https://ces.b2sg.org/event/nih-19sept18/
LOCATION:National Institutes of Health (NIH) campus\, Bethesda\, MD\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180920
DTEND;VALUE=DATE:20181022
DTSTAMP:20260828T053623
CREATED:20180920T051242Z
LAST-MODIFIED:20180920T051242Z
UID:20686-1537401600-1540166399@ces.b2sg.org
SUMMARY:Postdoctoral Associate
DESCRIPTION:The Zhao lab is seeking a highly motivated postdoctoral associate to study the role of RNA modification in stem cells and cancer development.  In analogous to DNA modification\, post-transcriptional modification is also identified on RNA.  Recently\, messenger RNA modification\, particularly methylation at the N6 position of adenosine or m6A\, has emerged as an exciting research area in epigenetics and RNA biology. The Zhao lab identified a protein complex that governs m6A formation. Using loss-of-function studies\, they discovered that m6A mRNA modification is essential for the proliferation and self-renewal of embryonic and neural stem cells. Mechanistically\, they reported that m6A regulates gene expression via shortening of the half-line of mRNAs or interacting with histone modifiers.  Please refer to their publications for further information (Nature Cell Biology 16 (2): 191-8\, Feb. 2014; Nature Neuroscience 21 (2): 195-206\, Feb. 2018). Currently\, we are digging deeper into the biological function and molecular mechanism of m6A in stem cells and cancer cells\, using a combination of biochemistry\, cell biology\, and high throughout sequencing technologies. \n\nRequired Experience \nEducation and/or Experience: \n\nA highly motivated Ph.D graduate with background in RNA biology\, cancer biology\, and/or molecular biology is encouraged to apply. 
URL:https://ces.b2sg.org/event/sbp-20sept18/
LOCATION:Sanford Burnham Prebys Medical Discovery Institute\, 10901 N Torrey Pines Rd\, La Jolla\, CA\, 92037\, United States
CATEGORIES:Jobs
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