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X-WR-CALNAME:Cancer Epigenetics Society
X-ORIGINAL-URL:https://ces.b2sg.org
X-WR-CALDESC:Events for Cancer Epigenetics Society
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TZID:Europe/Paris
BEGIN:DAYLIGHT
TZOFFSETFROM:+0100
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TZNAME:CEST
DTSTART:20180325T010000
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DTSTART:20181028T010000
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180906
DTEND;VALUE=DATE:20181008
DTSTAMP:20260828T182406
CREATED:20180906T114918Z
LAST-MODIFIED:20180906T114918Z
UID:20603-1536192000-1538956799@ces.b2sg.org
SUMMARY:Postdoctoral Research Associate
DESCRIPTION:A postdoctoral scholar position in the areas of genomics\, stem cell biology\, and leukemia is available in the laboratory of Dr. Grant Challen at Washington University School of Medicine in St. Louis. The Challen lab studies the epigenetic regulation of normal and malignant hematopoiesis. The successful applicant will be responsible for characterizing the roles of epigenetics in stem cell differentiation and blood cancer transformation. Our lab uses a variety of cutting edge technologies coupled with traditional cell culture\, molecular biology and mouse genetic models. The Hematopoietic Development and Malignancy (HDMP) program of the Siteman Cancer Center at Washington University in St. Louis provides us access to a variety of specialized research cores to facilitate our projects. Motivated candidates with a PhD or MD with a strong background in molecular and cellular biology\, cancer research and epigenetics are encouraged to apply. For the latest updates about our lab research\, please visit our lab website (www.challenlab.com) and lab Twitter feed (@challenlab). \n  \nPRIMARY DUTIES & RESPONSIBILITIES: \n\nDesign\, plan\, execute and interpret complex experiments integrating cell culture\, mouse models\, and genome sequencing data.\nAbility to independently generate testable hypotheses.\nIntegrated analysis of molecular data.\nAnalyze and interpret results to communicate with others and produce presentations and scientific publications is required.\nAssist in grant preparation and reporting.\nMaintain conformity with ethical standards in research.\nMaintain compliance with good laboratory practice including the maintenance of adequate research records\nCollegial conduct towards co-trainees\, staff members and members of the research group.\n\n\n\n\n\n\n\n\nRequired Qualifications\n\n\n\n\n\n\n\nThe appointee has earned a Ph.D.\, M.D. or equivalent terminal or doctoral degree. \n\n\n\n\n\n\n\n\nPreferred Qualifications\n\n\n\n\n\n\n\n\nApplicants should have a graduate degree in developmental biology\, genetics\, or related field.\nPrevious experience with mouse models\, flow cytometry\, cancer genomics\, and next-generation sequencing applications would be an advantage but is not essential.\nThe successful candidate will be self-motivated\, eager to acquire new knowledge and skills on a regular basis\, and must demonstrate critical thinking skills.\nThe ability to analyze and interpret results to communicate with others and produce scientific publications is required.
URL:https://ces.b2sg.org/event/wu-6sep18/
LOCATION:Washington University School of Medicine in St. Louis\, 660 S Euclid Ave\, St. Louis\, MO\, 63110\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180908
DTEND;VALUE=DATE:20181010
DTSTAMP:20260828T182406
CREATED:20180908T142355Z
LAST-MODIFIED:20180908T142355Z
UID:20607-1536364800-1539129599@ces.b2sg.org
SUMMARY:Post Doctoral Associate
DESCRIPTION:Seeking a highly motivated\, organized\, and responsible individual to lead a major component of our new cancer genetics and epigenetics lab\, as a foundation for their career advancement in academia or industry. Candidates will leverage cancer genomics and epigenomics data that we have generated in a variety of pediatric and adult brain tumors to undertake experiments in functional discovery\, validation\, as well as the development of integrated large-scale datasets using new genetic technologies. The ideal candidate will demonstrate a willingness to learn new concepts and technical skills\, but most importantly harbor an enthusiasm for working in a team-based environment and interfacing with national and international collaborative efforts. \n\nDesigns and conducts laboratory research experiments.\nDocuments\, interprets\, and presents results of experiments and reports to principal investigators.\nCollects\, compiles and analyses data; maintains records.\nWrites manuscripts for scientific publication\nWorks with maintaining mice\, performing procedures related to their project.\nUtilizes advanced computer programs with guidance.\nTrains less experienced members of the lab and assisting with technical procedures\n\nRequired: Doctoral degree with experience related to responsibilities/duties. Candidates more than 3 years from receiving their PhD will not be considered. An ideal candidate will have a strong foundation in molecular biology based techniques\, experience with animal handling and procedures\, and have a willingness to learn/work with complex computational software (R\, unix\, python\, perl).
URL:https://ces.b2sg.org/event/baylor-8sept18/
LOCATION:Baylor College of Medicine\, 1 Baylor Plaza\, Houston\, TX\, 77030\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180909
DTEND;VALUE=DATE:20181011
DTSTAMP:20260828T182406
CREATED:20180909T114433Z
LAST-MODIFIED:20180909T114433Z
UID:20609-1536451200-1539215999@ces.b2sg.org
SUMMARY:Research Fellow
DESCRIPTION:The laboratory of Professor Xiaole Shirley Liu (http://liulab.dfci.harvard.edu/) at Dana-Farber Cancer Institute and Harvard T.H.Chan School of Public Health invites applicants for a computational biology postdoctoral position. The research in the laboratory focuses on designing bioinformatics algorithms and integrative genomics approaches to model gene regulation\, find novel drug targets and combinations\, and predict response to targeted and immunotherapies in cancer. Recently Dr. Liu became the PI of the NCI Cancer Immunologic Data Commons (CIDC) Center to develop the bioinformatics algorithms and infrastructure to integrate comprehensive profiling of all NCI-sponsored immunoncology trials\, with the goal of predicting cancer immunotherapy outcomes. \n\nQualifications\n\n\n\nIdeal applicant should have:\n\nA PhD degree in related field (bioinformatics\, physics\, statistics\, engineering\, etc) received in the last 3 years\nStrong quantitative background (machine learning\, Bayesian inference\, etc.) or computational genomics experiences (high throughput sequence analysis\, etc.)\nStrong programming skills: ((Python | C | C++ | Java) & R)\nAt least two first authored English papers (or three if co-first authors) with submitted\, accepted or published status in journals\nGood spoken and written communication skills in English\n\nInterested applicants should submit CV\, a letter of interest with a one-page proposal for a project to be conducted in the Liu Lab\, and contact of three references to xsliu@jimmy.harvard.edu with subject line “Postdoctoral application”.
URL:https://ces.b2sg.org/event/df-9sept18/
LOCATION:Dana-Farber Cancer Institute\, 450 Brookline Avenue\, Boston\, MA\, 02215\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/11/Dana-Farber.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180910
DTEND;VALUE=DATE:20181012
DTSTAMP:20260828T182406
CREATED:20180910T072448Z
LAST-MODIFIED:20180910T072448Z
UID:20611-1536537600-1539302399@ces.b2sg.org
SUMMARY:Associate/Full Professor
DESCRIPTION:The Department of Nutritional Sciences invites applications for a 9 month\, tenure eligible\, full salaried Associate/Full Professor position supporting the Precision Wellness Initiative in emerging areas at the University of Arizona\, including aging\, brain (cognitive) health\, and inflammatory/metabolic diseases. The position’s duties will consist of 80% research and 20% instruction. \nThe revolutions in genomic\, epigenomic\, metabolomic\, imaging\, information\, and data science technologies have provided extraordinary opportunities to advance population wellness and optimize treatments\, lifestyles and preventives for individuals. The Precision Wellness Initiative at the University of Arizona is designed to enhance research\, education training\, and service programs that use these advanced tools\, and technologies to discover how genetics\, lifestyle and environmental factors (such as diet\, social factors and exercise) impact individual health. The ultimate goal of this Initiative is to discover and impart novel data-driven approaches and competences to personalize human disease prevention thereby promoting wellness throughout the human life span. \nResearch: Candidates for this position are expected to have research experience and interests in precision nutrition and health as it relates to aging\, brain health\, or inflammatory/metabolic diseases. They are also expected to have a strong background and expertise in data-driven science with a special emphasis on omics-based translational research. Candidate qualifications include a Ph.D. degree in nutrition science\, genetics\, genomics\, physiology\, pharmacology\, or cellular/molecular medicine or a related discipline\, high research productivity\, a record of success in obtaining external funding\, experienced teaching in omics-based technologies\, precision nutrition/wellness and/or precision health. Additional research strengths and skills considered include:\n– research experience developing nutritional and preventive interventions\, prognostic indicators\, and physiologic/structural/behavioral in vivo measurement systems for human diseases\n– research experience on the effect of nutritional/lifestyle in preserving brain health\, cognitive function and maintaining neuroplasticity thereby impacting the progression of aging and enhancing healthy aging.\n– research experience in planning and implementation of integrative projects analyzing data from large-scale studies and model systems designed to examine the genetics\, proteomics\, and metabolomics of human diseases\n– experience in scientific leadership roles within multi-disciplinary groups conducting clinical trials and/or observational studies\n– sophisticated knowledge of and experience using public and proprietary bioinformatic databases for annotation of multi-dimensional results leading to inference on factors and processes acting in disease pathogenesis or pathophysiology\n– experience in analysis of large-scale data sets integrating findings on genetic and epigenetic variation with those on environmental/lifestyle factors that may act as effect modifiers or disease predictors/correlates\n– familiarity with emerging applications of machine learning/computational modeling techniques \n\nTeaching: Contribute to the undergraduate and graduate curriculum in following areas: precision health; omics-based translational research including nutrigenomics/nutrigenetics; inflammation\, and metabolism; natural history\, etiology\, pathogenesis and pathophysiology of age-related and inflammatory/metabolic diseases; natural bioactives; development of new undergraduate and graduate programs in precision health and disease prevention; other teaching according to expertise and need. Additionally\, the candidate will be expected to: \n– Establish and maintain an externally-funded and internationally-recognized research program in precision health/nutrition for health promotion and disease prevention. The program is expected to be interdisciplinary and build upon existing collaborations across colleges and centers of excellence.\n– Maintain a strong\, peer-reviewed publication record.\n– Mentor graduate students in the department of Nutritional Sciences.\n– Participate in the instruction of upper level undergraduate and/or graduate courses.\n– Serve on department\, college and university level committees as required
URL:https://ces.b2sg.org/event/az-10sept18/
LOCATION:University of Arizona\, Tuscon\, AZ\, 85721\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180911
DTEND;VALUE=DATE:20181013
DTSTAMP:20260828T182406
CREATED:20180911T084302Z
LAST-MODIFIED:20180911T084302Z
UID:20614-1536624000-1539388799@ces.b2sg.org
SUMMARY:Research Associate I
DESCRIPTION:The Buck Institute for Research on Aging is seeking a Research Associate Iin the Kennedy Laboratory. The Buck Institute is the only independent institute in the U.S. devoted solely to research on aging and age-related diseases such as Alzheimer’s\, Parkinson’s\, cancer\, arthritis\, diabetes\, and stroke. Our mission is to increase the healthspan\, the healthy years of life. Awarded a federal grant to establish interdisciplinary research in a new field called Geroscience\, Buck scientists work in a unique\, collaborative environment allowing them to initiate studies quickly and respond to new opportunities in fields such as stem cell research and regenerative medicine. Our scientists represent a variety of complementary fields\, including genetics\, epigenetics\, biochemistry\, molecular biology\, bioenergetics\, age-associated disease; and technological disciplines such as genomics\, proteomics\, protein interaction networks and bio-informatics. \nThe Buck Institute\, designed by world famous architect I.M. Pei\, is located in Novato\, California\, 25 miles north of the Golden Gate Bridge. \nPOSITION SUMMARY: \nThe Kennedy lab is focused on identifying conserved genes and genetic pathways involved in modulating aging. Scientists in the group use invertebrate model organisms such as yeast and C. elegans to identify genes modulating aging and candidate mechanisms by which they act. These approaches lead to hypotheses that can be tested in mice. The ultimate goal is to understand the aging process in humans and to develop approaches to mitigate age-associated diseases. We are seeking a Research Assistant to drive yeast projects within the lab. \nKEY RESPONSIBILITIES: \n\nDrive the progress of yeast research: replicative lifespan dissection of yeast and organization of strains and basic manipulations.\nBack up laboratory members with regard to: experiments\, documentation of experimental results including data entry and other data management tasks\, analysis and interpretation and reporting of results where necessary\, under the guidance of the PI\, director of the lab or postdoctoral fellows.\nHandle administrative duties that enable the smooth operation of the lab\, including but not limited to: preparing liquid and plate media and common buffers / solutions; aiding in lab organization; ordering supplies; participating in the general care and maintenance of equipment; obtaining environmental safety approvals; and assisting in recruitment efforts of future lab members.\nPerform other duties as assigned.\n\nEDUCATION: \n\nBA/BS in genetics\, biology or related science and knowledge of\, or experience with\, the basic techniques or methods required by the position; or an equivalent combination of education and experience.\nProficient with basic molecular biology\, cell biology\, and protein chemistry laboratory techniques; experience with mammalian cells and tissues\, preferred.\nExcellent ability to communicate analyses orally & in writing; excellent organizational skills & record keeping; proficiency in MS Word/Excel/PowerPoint.\n\nEXPERIENCE: \n\nGenerally requires a minimum of 0-2 years’ experience with a Bachelor’s degree.
URL:https://ces.b2sg.org/event/buck-11sept18/
LOCATION:Buck Institute\, 8001 Redwood Boulevard\, Novato\, CA\, 94945\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180912
DTEND;VALUE=DATE:20181014
DTSTAMP:20260828T182406
CREATED:20180912T060552Z
LAST-MODIFIED:20180912T060552Z
UID:20616-1536710400-1539475199@ces.b2sg.org
SUMMARY:Research Assistant Professor
DESCRIPTION:The School of Biological Sciences\, University of Nebraska\, Lincoln\, NE\, USA\, seeks applications for a Research Assistant Professor to work on bioinformatics or computational biology\, genomics\, epigenetics\, omics-data integration\, etc. \nThe successful candidate will conduct the research on diverse projects in Dr. Chi Zhang’s Lab\, including bioinformatics tool development\, high-throughput data analysis\, and data integration. The candidate will also be responsible for lab management and assisting in the supervision of postdocs\, graduate students\, undergraduate students\, developing new areas of research\, and writing publications and grant proposals. Appointment is for three years with a possibility of further extension. \nMinimum Required Qualifications \n\nPhD degree in Bioinformatics\, Genomics\, Biological Sciences\, Biochemistry\, Biostatistics\, Physics\, or related fields.\n\n\nPractical experience of next-generation sequencing data analysis\, computational systems biology and data integration\, and solid knowledge in genomics\, gene expression/regulation and biological networks.\n\n\nProven skills in programming (such as Perl and R)\, experience with Linux/Unix environments and algorithm design.\n\n\nSolid background and knowledge in artificial intelligence (AI) and its application of biological data.\n\n\nSelf-motivated with excellent communication skills and an ability to work well in a team environment.\n\n\nAt least 7yr working experience in bioinformatics and/or computational biology.\n\nPreferred Qualifications \n\nEducation in computer science.\n\n\nBackground in both molecular biology and computer science.\n\n\nExperience in disease\, especially cancer\, related biological data analysis and/or plant genomics/genetics/epigenetics data analysis.
URL:https://ces.b2sg.org/event/neb-12sept18/
LOCATION:University of Nebraska\, 1400 R Street\, Lincoln\, NE\, 68588\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180914
DTEND;VALUE=DATE:20181016
DTSTAMP:20260828T182406
CREATED:20180914T094858Z
LAST-MODIFIED:20180914T094957Z
UID:20620-1536883200-1539647999@ces.b2sg.org
SUMMARY:Assistant Professor of Cancer Biology
DESCRIPTION:The Department of Cancer Biology at the Perelman School of Medicine at the University of Pennsylvania seeks candidates for an Assistant Professor position in the tenure track. The successful applicant will have experience in the field of cancer biology\, including cancer genetics and proteomics\, cancer cell biology\, tumor microenvironment\, cancer stem cells\, metastasis\, tumor immunology\, chemical biology\, cancer metabolism\, oncogenic signal transduction pathways\, genome integrity\, cancer epigenetics\, and cancer-related systems biology and bioinformatics. Responsibilities include establishment and maintenance of an externally funded independent research program\, as well as teaching and mentoring of students. Applicants must have an Ph.D. and/or M.D. degree and have demonstrated excellent qualifications in education and research. \nWe seek candidates who embrace and reflect diversity in the broadest sense. \nThe University of Pennsylvania is an EOE. Minorities/Women/Individuals with disabilities/Protected Veterans are encouraged to apply. \n\nApply for this position online at:  \nhttps://www.med.upenn.edu/apps/faculty_ad/index.php/g/d5157
URL:https://ces.b2sg.org/event/ibi-14sept18/
LOCATION:University of Pennsylvania\, 3400 Civic Center Blvd\, Philadelphia\, 19104\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180916
DTEND;VALUE=DATE:20181018
DTSTAMP:20260828T182406
CREATED:20180916T161801Z
LAST-MODIFIED:20180916T161801Z
UID:20644-1537056000-1539820799@ces.b2sg.org
SUMMARY:Postdoctoral Fellow
DESCRIPTION:A Postdoctoral position in Hematopoietic Stem Cell Biology is available in the laboratory of Peter Kurre\, M.D.\, at the Comprehensive Center for Bone Marrow Failure. The Laboratory has longstanding expertise in Hematopoietic stem cell biology\, including the development of preclinical approaches to Hematopoietic Stem Cell Gene Therapy. Ongoing work is focused on the development and refinement of anchoring lentivector designs with reduced propensity for genomic integration and mutagenicity. In a rapidly growing area of science\, investigations will involve a wide range of methods in virology\, vectorology\, cell-\, molecular biology imaging and bioinformatics tools. The postdoctoral fellow will\, under the direction/guidance of a mentor Dr. Mortimer Poncz\, assume responsibility for a specific\, on-going research project. \n\nThe successful candidate will be highly motivated and creative. Excellent verbal and written communication skills are critical. Scrupulous attention to detail\, good record keeping\, the ability to work independently\, in an expanding dynamic workgroup are essential. Candidates must have a recent Ph.D.\, D.V.M\, or M.D./Ph.D. in the biological sciences. Experience with mammalian cell culture (established cell lines and primary leukemia samples)\, molecular and cell biology techniques\, flow-cytometry\, and mouse models are desirable. The position is funded by NIH funds and private grants and by the The Children’s Hospital of Philadelphia\, with an understanding that the applicant will compete for trainee funding as part of their own career development. \n\nThe successful candidate will thrive in a multi-disciplinary\, collaborative team to extend\, refine and enhance skills necessary for professional and career development\, and broaden his/her scientific background by acquiring new research capabilities. It is expected that this individual will conduct independent scholarly research\, and will contribute directly to the overall research goals of the project and the research group. Postdocs will participate in project planning\, recording and interpretation/evaluation of data\, and communication of results. The candidate will acquire critical technical and lab management skills for their own career\, and to be proficient at manuscript/grant writing; postdocs will participate in seminars\, lectures\, poster sessions and presentations at national meetings. Postdoctoral fellows also will participate in the supervision of junior lab members\, develop new methods and protocols for research\, and assist with the development of other research projects in the lab. \nPostdoctoral fellows at The Children’s Hospital of Philadelphia receive mentored training in a premier scientific and collaborative environment that includes the resources of the adjacent University of Pennsylvania. \n\nTo learn more about the CHOP Research Institute and the research programs visit: http://research.chop.edu. \nJob Responsibilities \n\nConduct independent scholarly research and develop new methods and protocols\nParticipate in project planning\, recording and evaluation of data\nAcquire technical\, lab management and grant writing skills\nParticipate in seminars\, lectures\, poster sessions and presentation at national meetings\nSupervise junior lab members\nAssist with other research projects\n\nRequired Education and Experience \n\nA terminal degree PhD\, MD\, DVM\, etc.\nAccording to the CMS (Centers for Medicaid and Medicare Services) a copy of diploma or transcript is required as proof of academic achievement for all non-laboratory personnel performing non-waived POC testing
URL:https://ces.b2sg.org/event/chop-16sept18/
LOCATION:Children’s Hospital of Philadelphia\, 3401 Civic Center Blvd\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180917
DTEND;VALUE=DATE:20181019
DTSTAMP:20260828T182406
CREATED:20180917T055323Z
LAST-MODIFIED:20180917T055323Z
UID:20646-1537142400-1539907199@ces.b2sg.org
SUMMARY:Postdoctoral Associate
DESCRIPTION:A postdoctoral associate position is available in the laboratory of Dr. Jennifer Trowbridge at The Jackson Laboratory in Bar Harbor\, Maine\, to study epigenetic mechanisms governing hematopoietic stem cell lineage commitment and how deregulation of epigenetic modifications leads to myeloproliferative disorders including leukemia. The Trowbridge Lab offers a challenging but supportive environment. Past trainees have a noteworthy track record for obtaining grant funding and fellowships. For more information\, please visit: https://trowbridgelab.com.\n\n\n\nResponsibilities\n\n\n\nThe successful candidate will be able to plan\, develop\, execute\, and analyze an independent research project. \n\n\n\nQualifications\n\n\n\n\nM.D. or Ph.D. in biological or related sciences is required.\nStrong training background in molecular biology\, cell biology\, and/or epigenetics/epigenomics is preferred.\nOther areas of experience/training include stem cell biology\, immunology\, cancer biology\, or developmental biology.\nExceptional verbal and written communication skills;\nSelf-motivated and career-oriented individual preferred;\nExperience in flow cytometry and work with mouse models;\nMinimum of one 1st author paper from graduate work.\n\nTo apply\, a complete application must include a cover letter describing past research accomplishments\, research interests\, and career aspirations; a current CV; and the names of three references.
URL:https://ces.b2sg.org/event/jl-17sept18/
LOCATION:Jackson Laboratory\, 600 Main Street\, Bar Harbor\, ME\, 04609\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180918
DTEND;VALUE=DATE:20181020
DTSTAMP:20260828T182406
CREATED:20180918T171857Z
LAST-MODIFIED:20180918T172235Z
UID:20679-1537228800-1539993599@ces.b2sg.org
SUMMARY:Research Scientist - T Cell Metabolism
DESCRIPTION:Poseida Therapeutics\, Inc. is seeking an outstanding candidate to join our immuno-oncology team at La Jolla\, San Diego\, CA. The T Cell Metabolism Scientist will design and perform experiments optimizing the manufacture of chimeric antigen receptor (CAR)-T cell therapies of the T stem cell memory subset (TSCM)\, which are an ideal cell population for adoptive immunotherapy since they are long-lived\, self-renewing and multi-potent. The hypothetical attributes of a CAR-T product with a high percentage of TSCM include enhanced durability\, as well as potency against solid tumors. Investigation will focus on immunometabolism for understanding and optimizing the non-viral piggyBac™ CAR-Tscm manufacturing process via the use of in vitro human cell-based assays assessing T cell proliferation\, phenotype and function. The position will play a critical role in the evaluation and identification of manufacturing strategies for enhancing metabolic fitness and bioenergetic profile of CAR-T products.  The successful candidate will demonstrate excellent oral and written communication skills\, work well both independently and as part of a team\, and be able to work on multiple projects/product candidates simultaneously.  Broad expertise in cellular metabolism\, key regulatory pathways\, T cell culture\, and flow cytometry is required for this role.  The position is a hands-on\, laboratory-based role with the possibility of direct reports. \nPoseida Therapeutics is translating best-in-class gene engineering technologies into lifesaving cell therapies. The company is developing CAR T-cell immunotherapies for multiple myeloma\, prostate and other cancer types\, as well as gene therapies for orphan diseases. P-BCMA-101 is Poseida’s lead CAR-T therapy currently in Phase 1 clinical development for the treatment of multiple myeloma. Poseida has assembled a suite of industry-leading gene engineering technologies\, including the piggyBac™ DNA Modification System\, TAL-CLOVER™ and Cas-CLOVER™ site-specific nucleases\, and Footprint-Free™ Gene Editing (FFGE). For more information\, visit www.poseida.com. \nQualifications\nRequired Experience and Skills: \n\nPhD or equivalent in cell biology\, immunology\, or related field\nExpertise in metabolic pathways supporting T cell proliferation and differentiation (glycolysis\, fatty acid\, mitochondrial metabolism\, etc.)\nA detailed knowledge of lipid metabolism and salvage pathways used in nutrient-limiting\, solid tumor microenvironments\nUnderstanding of key T cell regulatory and differentiation pathways (PI3K-Akt-mTOR pathway in differentiation and memory formation\, etc.)\nExperience in the characterization\, culture\, expansion\, and manipulation of T cells\nAssessment of mitochondrial mass\, activity\, and spare respiratory capacity (Seahorse XF\, etc.)\nKnowledge of cellular and/or tumor immunology principles\, technologies\, and experimental techniques (cell culture\, in vitro cellular assays\, flow cytometry\, etc.)\nMulti-parameter flow cytometry and proficiency in FACS data analysis programs\nExperience designing\, executing\, and interpreting genomics and transcriptome assays (NGS\, RNA-Seq\, Single Cell RNA-Seq\, AmpliSeq\, etc.)\nCell separation technologies (e.g.\, Miltenyi AutoMACS) and FACS sorting\nAbility to organize\, communicate\, and present complex data sets to key stakeholders from diverse backgrounds\nExcellent oral and communication skills\n\nPreferred Experience and Skills: \n\nUnderstanding of epigenetic control of T cell differentiation\nExperience developing\, testing\, and/or utilizing CAR-T products\nFunctional assays measuring cellular activation\, cytokine release\, proliferation\, and killing\nWork with external academic\, biotechnology\, and contract research organizations
URL:https://ces.b2sg.org/event/poseida-18sept18/
LOCATION:Poseida Therapeutics\, 4242 Campus Point Court\, Suite 700\, San Diego\, CA\, 92121\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180919
DTEND;VALUE=DATE:20181021
DTSTAMP:20260828T182406
CREATED:20180919T070406Z
LAST-MODIFIED:20180919T070406Z
UID:20684-1537315200-1540079999@ces.b2sg.org
SUMMARY:Postdoctoral Fellow
DESCRIPTION:A post-doctoral position is available in Dr. Carol J. Thiele’s laboratory in the Cell & Molecular Biology Section in the Pediatric Oncology Branch at the NCI to study mechanisms of epigenetic dysregulation in pediatric neuroectodermal tumors. The broad goal of the laboratory is to study mechanisms of differentiation and how they are dysregulated in embryonal cancers with an eye towards developing novel therapeutic strategies based on an understanding of tumor biology. We use state-of-the-art screening strategies to identify key regulators of growth and differentiation. Current projects are mechanisms of regulation of EZH2 in neuroblastoma\, mESC reprogramming by tumor suppressors\, mechanisms of retinoid regulation of superenhancers\, regulation of tumor cell plasticity and mechanisms of epigenetic dysregulation in pediatric tumors. \n\n\n\n\nNumber of Positions:\n\n1\n\n\n\nC.V. Required:\n\nYes\n\n\n\nNumber of References Required:\n\n3\n\n\n\nBibliography Required:\n\nYes\n\n\n\nExperience Required:\n\n\nThe successful candidate should have a PhD in genetics/molecular biology/biochemistry/cell biology with less than 2 years of post-doctoral experience. Individuals with a strong background in molecular biology and experience in chromatin biology are encouraged to apply. Experience in genome-wide assays\, bioinformatics or deep sequencing is an additional asset. Qualified candidates should have strong communication skills\, and a demonstrated record of scientific achievement through peer-reviewed publications. Successful\, well-motivated candidates will join a multi-disciplinary team of researchers working in a basic/clinical translation environment. \n\n\n\n\nHow To Apply:\n\n\nInterested individuals should send a statement of research interests\, a curriculum vitae and bibliography and 3 letters of recommendation to Carol Thiele. \n\n\n\n\nContact Name:\n\nCarol Thiele\n\n\n\nContact E-mail:\n\nct47a@nih.gov\n\n\n\nContact Phone:\n\n240-858-3849
URL:https://ces.b2sg.org/event/nih-19sept18/
LOCATION:National Institutes of Health (NIH) campus\, Bethesda\, MD\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180920
DTEND;VALUE=DATE:20181022
DTSTAMP:20260828T182406
CREATED:20180920T051242Z
LAST-MODIFIED:20180920T051242Z
UID:20686-1537401600-1540166399@ces.b2sg.org
SUMMARY:Postdoctoral Associate
DESCRIPTION:The Zhao lab is seeking a highly motivated postdoctoral associate to study the role of RNA modification in stem cells and cancer development.  In analogous to DNA modification\, post-transcriptional modification is also identified on RNA.  Recently\, messenger RNA modification\, particularly methylation at the N6 position of adenosine or m6A\, has emerged as an exciting research area in epigenetics and RNA biology. The Zhao lab identified a protein complex that governs m6A formation. Using loss-of-function studies\, they discovered that m6A mRNA modification is essential for the proliferation and self-renewal of embryonic and neural stem cells. Mechanistically\, they reported that m6A regulates gene expression via shortening of the half-line of mRNAs or interacting with histone modifiers.  Please refer to their publications for further information (Nature Cell Biology 16 (2): 191-8\, Feb. 2014; Nature Neuroscience 21 (2): 195-206\, Feb. 2018). Currently\, we are digging deeper into the biological function and molecular mechanism of m6A in stem cells and cancer cells\, using a combination of biochemistry\, cell biology\, and high throughout sequencing technologies. \n\nRequired Experience \nEducation and/or Experience: \n\nA highly motivated Ph.D graduate with background in RNA biology\, cancer biology\, and/or molecular biology is encouraged to apply. 
URL:https://ces.b2sg.org/event/sbp-20sept18/
LOCATION:Sanford Burnham Prebys Medical Discovery Institute\, 10901 N Torrey Pines Rd\, La Jolla\, CA\, 92037\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180923
DTEND;VALUE=DATE:20181025
DTSTAMP:20260828T182406
CREATED:20180923T152228Z
LAST-MODIFIED:20180923T152228Z
UID:20689-1537660800-1540425599@ces.b2sg.org
SUMMARY:Postdoctoral Associate - Cancer Research
DESCRIPTION:The Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine has an exciting opportunity for a Postdoctoral Associate working in the laboratory of Dr. Feng-Chun Yang in the Department of Biochemistry and Molecular Biology. This position will focus on Cancer Epigenetics. The Postdoctoral Associate will perform cutting-edge research to understand the cellular/molecular mechanisms mediating pathogenesis of hematopoietic malignancies with a specific focus of ASXL1\, ASXL2 and NF1gene mutations.\n\nThe minimum qualifications for this position are as follows: Ph.D.\, M.D.\, or other doctoral level degree. Possess a strong background in cancer biology\, molecular and cellular biology\, biochemistry or a closely related field of study. Candidates must have successfully defended their thesis to be eligible for consideration. Prefer experience working with mammalian cells and mouse models of cancer. Applicants with experience in stem cell biology or who are familiar with bioinformatic tools (particularly next generation sequencing data analysis) are encouraged to apply. Must be goal-oriented\, proactive and hardworking with excellent organizational skills and passionate about making a difference in cancer research. Applicants should upload a CV when applying that contains a cover letter and complete list of publications.
URL:https://ces.b2sg.org/event/um-23sept18/
LOCATION:University of Miami\, 1320 S Dixie Hwy\, Coral Gables\, FL\, 33146\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180925
DTEND;VALUE=DATE:20181027
DTSTAMP:20260828T182406
CREATED:20180925T075652Z
LAST-MODIFIED:20180925T080342Z
UID:20691-1537833600-1540598399@ces.b2sg.org
SUMMARY:Clinical Geneticist
DESCRIPTION:HJF is seeking a Clinical Geneticist to support the MCC Cancer Genetics Program at the John P. Murtha Cancer Center (MCC) located at the Walter Reed National Military Medical Center (WRNMMC)\, Bethesda\, Maryland.  The MCC Cancer Genetics Program includes the Clinical Breast Care Project and the Clinical Genetics Service in WRNMMC.  HJF provides scientific\, technical and programmatic support services to MCC. \nThe John P. Murtha Cancer Center at Walter Reed Bethesda is a modern\, patient-centric\, tri-service military healthcare facility. Its comprehensive core of military and civilian oncologists and other cancer-trained clinicians and researchers provide multidisciplinary cancer-care delivery and patient-family support services. Our Cancer Center\, the only DoD Cancer Center of Excellence within the Military Health System\, offers its patients access to cutting-edge cancer diagnostic and treatment technologies. \nThe incumbent will serve as a Clinical Geneticist for the MCC Cancer Genetics Program in Walter Reed National Military Medical Center.  They will provide comprehensive genetic evaluation for clients and families with genetic\, genomic\, epigenetic\, pharmacogenetic conditions – suspected\, at risk\, proven or with a family history of such under the direction of the Principal Investigator. \nResponsibilities: \n\nServe as the Clinical Geneticist for the MCC Cancer Genetics Program in Walter Reed National Military Medical Center.\nProvides consultation to assigned staff of Walter Reed National Military Medical Center and partner Military Treatment Facilities.\nCoordinates with the other genetics professionals at Walter Reed National Military Medical Center in the planning\, development and evaluation of programs and services related to genetic counseling.\nProvides genetic services to individual patients and their family members in MCC Cancer Genetics Program and the Clinical Breast Care Project in Walter Reed National Military Medical Center.\nProvides both public and professional/academic education and participates in clinical research.\nPerforms other duties as needed.\n\nRequired Knowledge\, Skills\, and Abilities: Knowledge of procedures and techniques necessary for performing research tasks; ability to learn and become proficient in data acquisition and clinical responsibilities related to research protocols; excellent interpersonal skills. \nMinimum Education/Training Requirements: M.D. or D.O \nMinimum Experience: 6+ years experience in Clinical Genetics preferred.
URL:https://ces.b2sg.org/event/hjf-25sept18/
LOCATION:Henry M. Jackson Foundation\, 1200 5th Ave.\, Suite 1450\, Seattle\, WA\, 98101\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180926
DTEND;VALUE=DATE:20181028
DTSTAMP:20260828T182406
CREATED:20180926T161313Z
LAST-MODIFIED:20180926T161313Z
UID:20698-1537920000-1540684799@ces.b2sg.org
SUMMARY:Postdoctoral Scholar
DESCRIPTION:The Buisson Lab in the Department of Biological Chemistry at the University of California\, Irvine is seeking applicants for a Postdoctoral Scholar position. \nApplications are being sought from independent and motivated postdoctoral candidates interested in a multi-disciplinary approach to address important questions around genomic instability including: DNA damage\, DNA repair\, transcription and epigenetic control. Applicants must possess a Ph.D. degree to apply and must have one excellent first author publication in biochemistry\, molecular and cellular biology or a related field from their Ph.D. training period. In addition\, expertise in DNA damage/repair\, epigenetics and genomics is preferred but not required. \nThe Buisson lab focuses on understanding the mechanisms that cause DNA damage and genomic instability in cancer as well as the roles of tumor suppressor genes and oncogenes in DNA repair processes. These include investigating the mechanisms of DNA double-strand break repair and DNA replication through cellular\, biochemical\, genetic and structural biology approaches (Nature Structural & Molecular Biology\, 2010; Cell Reports\, 2014; Molecular Cell\, 2015; Molecular Cell\, 2017; Cancer Research\, 2017; Science\, 2018). \nFurther details about the Buisson Lab research can be found at: https://buissonlab.com. \nThe Buisson Lab is part of the Department of Biological Chemistry\, Chao Family Comprehensive Cancer Center\, and the Center for Epigenetics and Metabolism at UC Irvine. We are located in Southern California\, between Los Angeles and San Diego. For further details about UC Irvine and Southern California\, please visit https://uci.edu/. \nAdditional information regarding the position can be obtained by contacting: \nProfessor Rémi Buisson\nBuissonlab@gmail.com \nTo Apply: Interested candidates should apply through UC Irvine’s RECRUIT system located at: https://recruit.ap.uci.edu/apply/JPF04961. \nEach application must contain the following items: \n\nBrief statement of research interests and future goals\nCV detailing research experience\, publications\, any fellowships obtained during the training period\, and other relevant information\nList of any manuscripts in preparation or currently under review\nNames of 3 references that are familiar with the research experience of the candidate and who can provide letters of recommendation upon request
URL:https://ces.b2sg.org/event/irvine-26sept18/
LOCATION:UC Irvine\, Irvine\, CA\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180927
DTEND;VALUE=DATE:20181029
DTSTAMP:20260828T182406
CREATED:20180927T080301Z
LAST-MODIFIED:20180927T080356Z
UID:20700-1538006400-1540771199@ces.b2sg.org
SUMMARY:Research Fellow
DESCRIPTION:A Research Fellow position is available in the program of Dr. Keith Robertson. For more information about Dr. Robertson’s program\, please see: http://www.mayo.edu/research/faculty/robertson-keith-d-ph-d/bio-20035097 \nThe successful candidate will join the Epigenetic Etiology of Human Disease Laboratory to study the role of DNA epigenetic modifications in human disease. More specifically\, he/she will examine how DNA methylating and hydroxymethylating enzymes regulate their respective DNA epigenetic modifications and how these marks modulate expression and genome stability\, and interface with other epigenetic modifications. Disease focus areas of the laboratory include cancer (hepatocellular and renal)\, obesity\, and diabetes. Specific research areas include application of genome-wide epigenomics methods to decipher DNA methylation/hydroxymethylation defects in cancer and biochemical/cell culture-based techniques to study the regulation and interactions between chromatin remodeling factors (e.g. DNMTs\, TETs\, HMTases) and the roles of their target loci in driving disease. Techniques commonly used in the laboratory include: quantitative RT-PCR\, western blotting\, cell culture\, transfections\, bisulfite sequencing\, DNA immunoprecipitation\, pyrosequencing\, ChIP-qPCR\, ChIP-seq\, next-gen library preparation and sequencing\, Infinium 850k arrays\, bioinformatics analysis\, microscopy\, and biochemical analysis of protein function. Experience in one or more of these areas is a plus. The candidate will play a major role in the preparation of manuscripts that arise from this work and devote 100% effort to these tasks (no patient contact or other responsibilities). \nA Research Fellow at Mayo Clinic is a temporary position intended to provide training and education in research. Individuals will train in the research program of a Mayo Clinic principal investigator. Qualified individuals will demonstrate the potential for research as evidenced by their training and peer-reviewed publications and should become competitive for national research grants. Proof of English proficiency is required for J-1 Short-Term Scholars\, Research Scholars\, Professors\, Specialists\, and Student Interns sponsored by Mayo Clinic. 800146; J2WRTP \nMust have a Ph.D.\, M.D.\, or equivalent doctoral degree in a field deemed relevant by the program. Research Fellow is appropriate for individuals who have completed no more than one prior postdoctoral fellowship\, at Mayo Clinic or elsewhere. Please attach the following required documents at the time of application: \n\nCurrent curriculum vitae and bibliography\nThree letters of recommendation\, signed\, on letterhead\, describing:\n\nRelationship to the applicant.\nPast work/academic performance.\nWork qualities/personal conduct.\nOverall assessment of potential for success in research environment.\n\n\nDoctoral degree certification\, if applicable:\n\nOriginal or notarized copy of diploma or final transcript issued by school (English translation required).
URL:https://ces.b2sg.org/event/mayo-27sept18/
LOCATION:Mayo Clinic\, 200 1st St SW\, Rochester\, MN\, 55905\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180927
DTEND;VALUE=DATE:20181029
DTSTAMP:20260828T182406
CREATED:20180927T082233Z
LAST-MODIFIED:20180927T082233Z
UID:20703-1538006400-1540771199@ces.b2sg.org
SUMMARY:Postdoctoral Fellow - Cancer Immunology
DESCRIPTION:We are seeking a driven and accomplished postdoctoral fellow to join the Cancer Immunology Discovery (CID) group within the Oncology R&D (WRD) unit of Pfizer in South San Francisco\, California. \nThe successful candidate with lead a research project to understand how epigenetic mechanisms control the anti-tumor immune response\, and to translate the findings into better therapies with curative potential for cancer patients. \nThe project builds on promising preliminary data and applies cutting-edge technologies to address what is to date a major scientific question with great clinical implications. Guided by experienced mentors with strong academic track records\, the successful candidate will study fundamental questions in cancer immunology with the goal of publishing in high-impact journals. The postdoc will also interact extensively with leading scientists in small and large molecule drug discovery\, collaborate with computational\, early clinical\, and translational oncology colleagues across Pfizer\, present in internal and external conferences\, and receive mentorship to become a prolific independent scientific investigator. \nROLE RESPONSIBILITIES                                 \nThe successful candidate will work independently\, but with guidance by experienced mentors\, to: \n\nDiscover the novel mechanisms through which epigenetic enzymes regulate T cell activation\, differentiation\, trafficking and exhaustion\, in combination with I-O agents.\nDesign and perform studies to evaluate the anatomical distribution\, persistence and function of antigen-specific T cells in preclinical models of cancer.\nCollaborate with teams in tumor biology\, protein engineering\, computational biology\, clinical development to discover novel biology and as a result identify better treatments for cancer patients.\nPresent at group meetings\, internal and external conferences\, and publish in high impact journals.\nContribute to building a culture that embraces scientific excellence\, integrity\, effectiveness\, humility\, continuous learning and team work.\n\nBASIC QUALIFICATIONS  \n\nPh.D. in Immuno-oncology\, Immunology\, Cancer Biology or a comparable biological science\, with a strong track record of scientific publications.\n0-4 years of postdoctoral experience.\nSolid hands-on experience with conventional immunological techniques: immune cell isolation\, multi-color flow cytometry\, in vitro immune cell functional assays and in vivo tumor models.\nExperience in assessing T cell function\, differentiation\, exhaustion and memory development.\nMust have excellent organization and planning skills\, the ability to work in a fast-paced environment independently and as part of a team. Excellent verbal and written communication\, and strong motivation with a dedicated work ethic.\nAble to master new concepts and techniques quickly.\n\nPREFERRED QUALIFICATIONS \n\n2+ years research experience in T cell biology and/or epigenetics.\nStrong understanding of innate and adoptive immune systems.\nPrior experience or a strong interest in developing novel immunotherapies for cancer.\nHands-on experience in qRT-PCR\, ELISA\, Western blotting\, ChIP-seq\, RNA-seq\, ATAC-seq and CyTOF is desirable.\nHands-on experience in CRISPR\, RNAi\, lentiviral transduction and exogenous gene expression is a plus.\nHands-on experience in syngeneic and spontaneous tumor models\, adoptive cell transfer is desirable.
URL:https://ces.b2sg.org/event/pfizer-27sept18/
LOCATION:Pfizer – La Jolla\, CA\, 10350 N Torrey Pines Rd\, La Jolla\, CA\, 92037\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180930
DTEND;VALUE=DATE:20181031
DTSTAMP:20260828T182406
CREATED:20180930T073203Z
LAST-MODIFIED:20180930T073203Z
UID:20706-1538265600-1540943999@ces.b2sg.org
SUMMARY:Senior Scientist - Cancer Epigenetics
DESCRIPTION:Pfizer’s Oncology Research Unit (ORU) in La Jolla\, California\, is seeking a Senior Scientist (PhD level) focused on translating basic discoveries in the field of cancer epigenetics into novel therapeutics. \nThe Senior Scientist will work within a collaborative team of motivated and scientifically rigorous scientists to conduct preclinical research and advance drug programs in the field of cancer epigenetics. Our ideal candidate will have a strong background employing state-of-the art approaches to gain a broader understanding of epigenetic regulation in cancer biology. The candidate will translate basic research findings into therapeutic strategies\, utilizing genetic and pharmacological approaches to understand target mechanism of action and generate patient stratification strategies. The successful candidate will demonstrate a proven track record of scientific productivity as evidenced by first author publications in scientific journals. Experience in the integration of molecular profiling data including epigenomic (ATAC-seq\, ChIP-seq)\, transcriptomic\, proteomic\, and genomic datasets will be a plus. \nRole Responsibilities \n\nUtilize expertise in epigenetic biology to develop innovative strategies for understanding the role of epigenetic mechanisms in cancer progression\, drug resistance and immune modulation\nDesign\, execute and analyze/interpret experiments to advance mechanism of action studies\, develop patient responder hypotheses\, elucidate mechanisms of resistance  and identify rational drug combinations that can be translated to the clinic\nWork collaboratively with computational biology group to integrate complex data sets including epigenomic and other ‘omic’ data in pre-clinical settings for target validation and increased understanding of target biology\nInterface with discovery biology\, systems biology and computational biology groups to design\, develop\, and interpret datasets developed from genetic and pharmacological screens\nProactively seek out new information in the literature and incorporate this into individual project(s) as well as the overall program\nPresent research results and methodologies at weekly meetings with immediate supervisor and/or project leader\, project team meetings and other research forums\nContribute to building a culture that embraces scientific excellence\, urgency\, partnerships with key stakeholders\, continuous learning and improvement\, increasing technical skill base and cancer biology expertise; take a proactive role in personal growth and scientific development.\n\nBasic Qualifications  \n\nPhD in Molecular or Cellular Biology\, Genetics\, Pharmacology (or a comparable biological science) with a minimum of 3-5 years of relevant postdoctoral experience in an academic or pharmaceutical/biotech environment.\nExpertise in chromatin biology\, epigenetics and mechanism of transcriptional regulation as evidenced by publication in peer-reviewed journals. \nPreference for candidates with a strong track record in cancer drug discovery/translational research and the targeting of epigenetic pathways by small-molecule inhibitors.\nExpertise in techniques used for epigenetic/ transcriptional profiling including ChIP-seq\, ATAC-seq\, and RNA-seq\nAble to work in a team environment\, good communication skills and excellent leaderships skills.\n\nPreferred Qualifications \n\nProficiency in the use of bioinformatic software tools to support epigenomic data analysis including ATAC-seq\, ChIP-seq\, and RNA-seq.\nExtensive knowledge and understanding of other areas of tumor biology including but not limited to immuno-oncology\, oncogenic signaling\, cancer metabolism\, apoptosis and/or DNA damage and repair\nExperience in use of CRISPR-based techniques for gene knockout\, gene editing and as well as working knowledge of pooled CRISPR -based screening approaches
URL:https://ces.b2sg.org/event/pfizer-30sept18/
LOCATION:Pfizer – La Jolla\, CA\, 10350 N Torrey Pines Rd\, La Jolla\, CA\, 92037\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20181002
DTEND;VALUE=DATE:20181104
DTSTAMP:20260828T182406
CREATED:20181002T101047Z
LAST-MODIFIED:20181002T101047Z
UID:20708-1538438400-1541289599@ces.b2sg.org
SUMMARY:Senior Research Assistant
DESCRIPTION:The primary purpose of the Senior Research Assistant position is to provide supervision\, special training to technical personnel\, and /or highly technical work in research projects. Performs a series of experiments designed to supply specific information as a part of a larger project; an answer to questions in a limited field; or\, in development of improved techniques\, production methods or procedures in the Department of Epigenetics and Molecular Carcinogenesis. \nJOB SPECIFIC COMPETENCIES\n\nResearch Support Perform research or experimental tasks to supply information as part of a research project or laboratory. Responsible for planning and executing details of an experiment\, including set up\, timing (scheduled\, staffed\, planned)\, coordination of supplies and equipment at hand\, functionality of equipment\, trained personnel. Evaluate and interpret experimental results. Assemble\, operate and troubleshoot equipment. Compile/prepare tables and charts. Assist with preparation of grant applications and progress reports.\n\nExpertise and Specialization Apply background/experience in science\, using independent evaluation\, judgment and analysis. Perform research or experimental tasks in a limited field (niche) or specialty area. Master difficult\, advanced\, skills or technology. Develop and revise protocols\, procedures\, and techniques. Introduce/implement new technology. Participate in troubleshooting and resolving problems.\n\nLaboratory Organization Supervise technicians and oversee their training. May oversee educational appointees in their work and assist them as assigned or delegated. Assess availability of supplies and advise/recommend purchasing as needed. Contribute to the laboratory; assess need for back-up and cover as necessary; cross-train. May have delegated signing authority on routine purchases. Perform other duties as assigned.\n\nOther duties as assigned.\n\n\nREQUIREMENTS\n\nEducation: Bachelor’s degree in one of the natural sciences or related field.\n\nPreferred Education:Master’s Level Degree\n\nCertification: None\n\nPreferred Certification: None\n\nExperience: Three years of experience in scientific or experimental research work. With preferred degree\, one year of required experience.\n\nPreferred Experience: Extensive experience in cell culture studies including mammalian cell culture; transfections of cell lines; post-culture analysis (cell viability\, cell counting\, cytoxicity and proliferation assays). Experience with RNA interference\, shRNA and/or siRNA; Familiarity with CRISPR/Cas 9 and next-generation sequencing preparation. Past experience with lenti virus and retro virus mediated transduction of mammalian cell lines.
URL:https://ces.b2sg.org/event/mda-2oct18/
LOCATION:MD Anderson Cancer Center Smithville\, 1808 Park Rd 1C\, Smithville\, TX\, 78957\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20181006
DTEND;VALUE=DATE:20181108
DTSTAMP:20260828T182406
CREATED:20181006T103346Z
LAST-MODIFIED:20181006T104414Z
UID:20721-1538784000-1541635199@ces.b2sg.org
SUMMARY:Postdoctoral Fellow
DESCRIPTION:NIH funded postdoctoral position available immediately at Northwestern University in the Feinberg School of Medicine in the Department of Urology. The postdoctoral fellow will work closely with Joshua Meeks\, MD\, PhD in the Department of Urology and Stephen Miller\, PhD in the department of Microbiology and Immunology. Research projects associated with this fellowship include: 1) mechanisms of T-cell biology and immune activation in genitourinary disorders (including cancer)\, 2) mechanisms resistance to therapy\, 3) mechanisms of T cell tolerance 4) epigenetic regulation of T cell activity 5) novel checkpoint and immune regulatory therapies. \nCandidates are required to have US citizenship or permanent residence and a PhD or MD in Molecular biology\, or Immunology and/or comparable experience in these subjects. Preferred qualifications include experience with bioinformatics and next generation sequencing. Prior research in model systems (e.g.\, mouse models) is also considered an important criteria. \nProspective candidates will have the opportunity to submit publications\, as well as gain access to human trial specimens that will contribute to the next generation of therapies in immuno-oncology and benign urologic conditions that apply immunotherapy. In addition\, Northwestern University offers an extremely stimulating and nourishing academic environment\, with rich resources to facilitate career development for young scientists. \nFor consideration\, please send your cover letter\, CV\, and names of three references to: Dr. Joshua Meeks at\, joshua.meeks@northwestern.edu and jmeeks@nm.org. \nSpecific Responsibilities: \n\nTo oversee the molecular genetics lab including the maintain the supplies\, equipment and ordering of necessary materials;\nTo conduct laboratory experiments including mutation analysis and in situ hybridization as well as others to study melanoma cancer;\nTo help write grants and compete for funding;\nTo supervise students and other techs working in the genetics lab;\nTo help write and contribute to publications resulting from research done in the lab;\nPerforms other duties as assigned.\n\nMinimum Qualifications: \n\nPh.D. training in genetics or molecular biology competent in PCR\, mutational analysis\, and DNA sequencing.
URL:https://ces.b2sg.org/event/nwu-6oct18/
LOCATION:Northwestern University\, 633 Clark St\, Evanston\, IL\, 60208\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20181007
DTEND;VALUE=DATE:20181109
DTSTAMP:20260828T182406
CREATED:20181007T065154Z
LAST-MODIFIED:20181007T065300Z
UID:20725-1538870400-1541721599@ces.b2sg.org
SUMMARY:Research/Lab Assistant
DESCRIPTION:A part time\, temporary position is available in the laboratory of Dr. Aparna Sertil in the Department of Basic Medical Sciences at the University of Arizona College of Medicine-Phoenix\, investigating the role of tumor microenvironment and stress signaling in tumor dormancy\, therapy resistance and cancer stem cell plasticity. The successful candidate will be a well-rounded\, enthusiastic individual with training in Cell Biology\, Molecular Biology\, Biochemistry or related field and experience performing research in a laboratory setting. This individual should be detailed oriented\, conscientious\, and able to follow instructions and have the ability to communicate in a clear\, concise manner orally and in writing. \nDuties & Responsibilities \n\nPerforms standard laboratory procedures such as maintaining cell cultures requiring the use of sterile technique\, processing tissue samples and preparing slides using staining techniques.\n\n\nPerforms routine experiments and analyses\, as requested.\n\n\nMaintains animal colonies which includes feeding\, watering\, sexing and breeding the subjects.\n\n\nCompiles data and assists in routine preliminary analyses; maintains research data in laboratory notebook\, writes summary reports and reports findings to investigator.\n\n\nAssists in performing surgeries and dissections on animals which includes setting up equipment and supplies\, preparing animals for surgery\, anesthetizing and monitoring heart rate of animal and harvesting tissue samples and readily accessible organs.\n\n\nCollects samples or data and performs lab analysis and/or quantifies and tabulates results.\n\n\nOperates laboratory and experimental equipment such as microtomes\, microscopes\, electron microscopes\, spectrophotometers\, centrifuges\, analytical balances\, photometers and spectrometers; makes minor repairs and makes arrangements for major repairs to be performed.\n\n\nOrganizes supplies\, materials or equipment and sets-up equipment for laboratory experiments or demonstrations; may perform minor equipment maintenance.\n\n\nMaintains detailed records of controlled substances in the laboratory; packages waste material and arranges for disposal according to established procedures.\n\n\nAssists with basic mathematical and statistical analyses.\n\n\nFollows established procedures to prepare solutions\, media and reagents using arithmetical calculations for measuring; performs library research to find appropriate procedures\, as required.\n\n\nCleans glassware and other laboratory equipment or materials using appropriate standards; keeps laboratory area clean.\n\n\nPerforms clerical tasks such as filing\, typing\, labeling and billing; inventories and requisitions supplies and materials.\n\n\nAssists in training volunteers working in the laboratory.\n\nKnowledge\, Skills\, & Abilities \n\nKnowledge of the methods\, materials and techniques used in laboratory and research work.\n\n\nKnowledge of research and laboratory equipment appropriate to the area of the assignment.\n\n\nAbility to effectively communicate.\n\n\nSkill in recording research data.
URL:https://ces.b2sg.org/event/ua-7oct18/
LOCATION:University of Arizona\, Tuscon\, AZ\, 85721\, United States
CATEGORIES:Jobs
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END:VCALENDAR