BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Cancer Epigenetics Society - ECPv5.3.2.1//NONSGML v1.0//EN
CALSCALE:GREGORIAN
METHOD:PUBLISH
X-WR-CALNAME:Cancer Epigenetics Society
X-ORIGINAL-URL:https://ces.b2sg.org
X-WR-CALDESC:Events for Cancer Epigenetics Society
BEGIN:VTIMEZONE
TZID:Europe/Paris
BEGIN:DAYLIGHT
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:CEST
DTSTART:20180325T010000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:+0200
TZOFFSETTO:+0100
TZNAME:CET
DTSTART:20181028T010000
END:STANDARD
END:VTIMEZONE
BEGIN:VEVENT
DTSTART;VALUE=DATE:20181002
DTEND;VALUE=DATE:20181104
DTSTAMP:20260829T171235
CREATED:20181002T101047Z
LAST-MODIFIED:20181002T101047Z
UID:20708-1538438400-1541289599@ces.b2sg.org
SUMMARY:Senior Research Assistant
DESCRIPTION:The primary purpose of the Senior Research Assistant position is to provide supervision\, special training to technical personnel\, and /or highly technical work in research projects. Performs a series of experiments designed to supply specific information as a part of a larger project; an answer to questions in a limited field; or\, in development of improved techniques\, production methods or procedures in the Department of Epigenetics and Molecular Carcinogenesis. \nJOB SPECIFIC COMPETENCIES\n\nResearch Support Perform research or experimental tasks to supply information as part of a research project or laboratory. Responsible for planning and executing details of an experiment\, including set up\, timing (scheduled\, staffed\, planned)\, coordination of supplies and equipment at hand\, functionality of equipment\, trained personnel. Evaluate and interpret experimental results. Assemble\, operate and troubleshoot equipment. Compile/prepare tables and charts. Assist with preparation of grant applications and progress reports.\n\nExpertise and Specialization Apply background/experience in science\, using independent evaluation\, judgment and analysis. Perform research or experimental tasks in a limited field (niche) or specialty area. Master difficult\, advanced\, skills or technology. Develop and revise protocols\, procedures\, and techniques. Introduce/implement new technology. Participate in troubleshooting and resolving problems.\n\nLaboratory Organization Supervise technicians and oversee their training. May oversee educational appointees in their work and assist them as assigned or delegated. Assess availability of supplies and advise/recommend purchasing as needed. Contribute to the laboratory; assess need for back-up and cover as necessary; cross-train. May have delegated signing authority on routine purchases. Perform other duties as assigned.\n\nOther duties as assigned.\n\n\nREQUIREMENTS\n\nEducation: Bachelor’s degree in one of the natural sciences or related field.\n\nPreferred Education:Master’s Level Degree\n\nCertification: None\n\nPreferred Certification: None\n\nExperience: Three years of experience in scientific or experimental research work. With preferred degree\, one year of required experience.\n\nPreferred Experience: Extensive experience in cell culture studies including mammalian cell culture; transfections of cell lines; post-culture analysis (cell viability\, cell counting\, cytoxicity and proliferation assays). Experience with RNA interference\, shRNA and/or siRNA; Familiarity with CRISPR/Cas 9 and next-generation sequencing preparation. Past experience with lenti virus and retro virus mediated transduction of mammalian cell lines.
URL:https://ces.b2sg.org/event/mda-2oct18/
LOCATION:MD Anderson Cancer Center Smithville\, 1808 Park Rd 1C\, Smithville\, TX\, 78957\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/05/MDAnderson.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20181006
DTEND;VALUE=DATE:20181108
DTSTAMP:20260829T171235
CREATED:20181006T103346Z
LAST-MODIFIED:20181006T104414Z
UID:20721-1538784000-1541635199@ces.b2sg.org
SUMMARY:Postdoctoral Fellow
DESCRIPTION:NIH funded postdoctoral position available immediately at Northwestern University in the Feinberg School of Medicine in the Department of Urology. The postdoctoral fellow will work closely with Joshua Meeks\, MD\, PhD in the Department of Urology and Stephen Miller\, PhD in the department of Microbiology and Immunology. Research projects associated with this fellowship include: 1) mechanisms of T-cell biology and immune activation in genitourinary disorders (including cancer)\, 2) mechanisms resistance to therapy\, 3) mechanisms of T cell tolerance 4) epigenetic regulation of T cell activity 5) novel checkpoint and immune regulatory therapies. \nCandidates are required to have US citizenship or permanent residence and a PhD or MD in Molecular biology\, or Immunology and/or comparable experience in these subjects. Preferred qualifications include experience with bioinformatics and next generation sequencing. Prior research in model systems (e.g.\, mouse models) is also considered an important criteria. \nProspective candidates will have the opportunity to submit publications\, as well as gain access to human trial specimens that will contribute to the next generation of therapies in immuno-oncology and benign urologic conditions that apply immunotherapy. In addition\, Northwestern University offers an extremely stimulating and nourishing academic environment\, with rich resources to facilitate career development for young scientists. \nFor consideration\, please send your cover letter\, CV\, and names of three references to: Dr. Joshua Meeks at\, joshua.meeks@northwestern.edu and jmeeks@nm.org. \nSpecific Responsibilities: \n\nTo oversee the molecular genetics lab including the maintain the supplies\, equipment and ordering of necessary materials;\nTo conduct laboratory experiments including mutation analysis and in situ hybridization as well as others to study melanoma cancer;\nTo help write grants and compete for funding;\nTo supervise students and other techs working in the genetics lab;\nTo help write and contribute to publications resulting from research done in the lab;\nPerforms other duties as assigned.\n\nMinimum Qualifications: \n\nPh.D. training in genetics or molecular biology competent in PCR\, mutational analysis\, and DNA sequencing.
URL:https://ces.b2sg.org/event/nwu-6oct18/
LOCATION:Northwestern University\, 633 Clark St\, Evanston\, IL\, 60208\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/png:https://ces.b2sg.org/wp-content/uploads/2018/04/northwestern-u-min-1.png
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20181007
DTEND;VALUE=DATE:20181109
DTSTAMP:20260829T171235
CREATED:20181007T065154Z
LAST-MODIFIED:20181007T065300Z
UID:20725-1538870400-1541721599@ces.b2sg.org
SUMMARY:Research/Lab Assistant
DESCRIPTION:A part time\, temporary position is available in the laboratory of Dr. Aparna Sertil in the Department of Basic Medical Sciences at the University of Arizona College of Medicine-Phoenix\, investigating the role of tumor microenvironment and stress signaling in tumor dormancy\, therapy resistance and cancer stem cell plasticity. The successful candidate will be a well-rounded\, enthusiastic individual with training in Cell Biology\, Molecular Biology\, Biochemistry or related field and experience performing research in a laboratory setting. This individual should be detailed oriented\, conscientious\, and able to follow instructions and have the ability to communicate in a clear\, concise manner orally and in writing. \nDuties & Responsibilities \n\nPerforms standard laboratory procedures such as maintaining cell cultures requiring the use of sterile technique\, processing tissue samples and preparing slides using staining techniques.\n\n\nPerforms routine experiments and analyses\, as requested.\n\n\nMaintains animal colonies which includes feeding\, watering\, sexing and breeding the subjects.\n\n\nCompiles data and assists in routine preliminary analyses; maintains research data in laboratory notebook\, writes summary reports and reports findings to investigator.\n\n\nAssists in performing surgeries and dissections on animals which includes setting up equipment and supplies\, preparing animals for surgery\, anesthetizing and monitoring heart rate of animal and harvesting tissue samples and readily accessible organs.\n\n\nCollects samples or data and performs lab analysis and/or quantifies and tabulates results.\n\n\nOperates laboratory and experimental equipment such as microtomes\, microscopes\, electron microscopes\, spectrophotometers\, centrifuges\, analytical balances\, photometers and spectrometers; makes minor repairs and makes arrangements for major repairs to be performed.\n\n\nOrganizes supplies\, materials or equipment and sets-up equipment for laboratory experiments or demonstrations; may perform minor equipment maintenance.\n\n\nMaintains detailed records of controlled substances in the laboratory; packages waste material and arranges for disposal according to established procedures.\n\n\nAssists with basic mathematical and statistical analyses.\n\n\nFollows established procedures to prepare solutions\, media and reagents using arithmetical calculations for measuring; performs library research to find appropriate procedures\, as required.\n\n\nCleans glassware and other laboratory equipment or materials using appropriate standards; keeps laboratory area clean.\n\n\nPerforms clerical tasks such as filing\, typing\, labeling and billing; inventories and requisitions supplies and materials.\n\n\nAssists in training volunteers working in the laboratory.\n\nKnowledge\, Skills\, & Abilities \n\nKnowledge of the methods\, materials and techniques used in laboratory and research work.\n\n\nKnowledge of research and laboratory equipment appropriate to the area of the assignment.\n\n\nAbility to effectively communicate.\n\n\nSkill in recording research data.
URL:https://ces.b2sg.org/event/ua-7oct18/
LOCATION:University of Arizona\, Tuscon\, AZ\, 85721\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/06/uni-arizona.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20181008
DTEND;VALUE=DATE:20181110
DTSTAMP:20260829T171235
CREATED:20181008T070634Z
LAST-MODIFIED:20181008T070634Z
UID:20728-1538956800-1541807999@ces.b2sg.org
SUMMARY:Faculty Position
DESCRIPTION:The Department of Biochemistry and Molecular Biology at Mayo Clinic is seeking an exceptional biomedical scientist studying molecular mechanisms of disease to run an independent and nationally/internationally-recognized research program. \nPosition description \nThis person will hold academic rank at Mayo Clinic commensurate with experience and qualifications. Research expertise may be in any biomedical field\, including but not limited to biochemistry\, biophysics\, cell biology\, developmental/ regenerative biology\, epigenetics\, metabolism\, and molecular biology. The successful candidate will be expected to work collaboratively with colleagues and may align with one or more institutional centers (e.g.\, biomedical discovery\, cancer\, individualized medicine\, pediatrics\, regenerative medicine). \nCredentials of a successful candidate will include a doctoral degree in a biomedical science field (PhD\, MD/PhD\, MD or equivalent) and rigorous postdoctoral training. Junior investigators should have a strong publication record; evidence of successful competition for external funding is preferred. Mid-career and senior investigators must have a strong publication record and history of NIH- or equivalent extramural funding. \nLicense or certification \nCredentials of a successful candidate will include a doctoral degree in a biomedical science field (PhD\, MD/PhD\, MD or equivalent) and rigorous postdoctoral training. Junior investigators should have a strong publication record; evidence of successful competition for external funding is preferred. Mid-career and senior investigators must have a strong publication record and history of NIH- or equivalent extramural funding. \nApplications should include a cover letter\, CV\, statement of research interests\, and contact information for at least three potential references.
URL:https://ces.b2sg.org/event/mayo-8oct18/
LOCATION:Mayo Clinic\, 200 1st St SW\, Rochester\, MN\, 55905\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/png:https://ces.b2sg.org/wp-content/uploads/2017/08/mayo-clinic_416x416.png
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20181009
DTEND;VALUE=DATE:20181111
DTSTAMP:20260829T171235
CREATED:20181009T061755Z
LAST-MODIFIED:20181009T061755Z
UID:20730-1539043200-1541894399@ces.b2sg.org
SUMMARY:Postdoctoral Research Fellow
DESCRIPTION:We seek a motivated post-doctoral research fellow to join our ongoing studies on the cancer-causing potential of new and emerging tobacco products\, including electronic cigarettes and heat-not-burn devices. Candidates are expected to have working knowledge of routine molecular biology techniques used for cancer epigenetic studies. Hands-on experience with assays to detect aberrant DNA methylation and/or histone modifications is a plus. Priority will be given to those who have prior work experience with microarray- or next generation sequencing-based platforms. Candidates with successful publication record in scholarly journals are preferred. \nTo submit an application\, please\, visit: \nhttps://usccareers.usc.edu/job/los-angeles/postdoctoral-scholar-research-associate/1209/6248579
URL:https://ces.b2sg.org/event/usc-9oct18/
LOCATION:University of Southern California\, Los Angeles\, CA\, 90007\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/11/usc-logo.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20181011
DTEND;VALUE=DATE:20181113
DTSTAMP:20260829T171235
CREATED:20181011T071507Z
LAST-MODIFIED:20181011T071507Z
UID:20742-1539216000-1542067199@ces.b2sg.org
SUMMARY:Senior Scientist - Cell Biology (Epigenetics)
DESCRIPTION:We are seeking a highly motivated scientist to join our Epigenetics Center of Excellence. Reporting to the Director / Epigenetic Drug Discovery Head\, the candidate will be based in San Diego\, CA. He/she will be expected to design\, plan and execute biological studies for identifying new targets and to support drug discovery projects from target identification to nomination of development candidates. This role will work closely with other functions such as Bioinformatics\, Biochemistry\, Chemistry and Pharmacology to coordinate the progress of projects. With an emphasis in Oncology\, the scope of work will cover also Immuno-Oncology\, Inflammation and Neurodegenerative diseases. It will involve collaborative work with academic centers and business partners as well.  \nThe successful candidate will have a strong foundation in transcription regulation in cancer with previous experience in Drug Discovery.  \nSkills/Knowledge Required :\nPh.D. in Biology or related scientific discipline with at least 6 years of relevant cancer research experience\, preferably in Industry \nProficient in cell biology including shRNA and CRISPR technologies \nExperience in target validation\, functional and biomarker cell-based assay development. \nExperience in performing and/or interpreting epigenetic profiling studies is highly desired (DNA methylation\, RNA-sequencing\, ChIP-sequencing and ATAC-sequencing). \nSolid experience in Drug Discovery. \nHighly motivated\, innovative and strong team player. Experience to work in a cross-functional team \nExcellent time management and organizational skill. \nStrong communication skills\, both written and oral. \nStrong ability to work in a fast-paced environment is essential. \nStrong interpersonal and communication skills with a demonstrated ability for creative thinking and problem solving. 
URL:https://ces.b2sg.org/event/celgene1-11oct18/
LOCATION:Celgene San Diego\, 10300 Campus Point Dr\, San Diego\, CA\, 92121\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/png:https://ces.b2sg.org/wp-content/uploads/2017/08/celgene-1-e1503843775806.png
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20181011
DTEND;VALUE=DATE:20181113
DTSTAMP:20260829T171235
CREATED:20181011T071738Z
LAST-MODIFIED:20181011T071738Z
UID:20743-1539216000-1542067199@ces.b2sg.org
SUMMARY:Senior Scientist
DESCRIPTION:We are seeking a talented highly motivated research scientist to join our new Sequencing Research capability in San Diego. The successful candidate will work on novel NGS profiling approaches to elucidate disease state from patient biospecimens\, PDX and organoid models\, and multi-cellular pre-clinical disease models. Work performed will contribute to therapeutic discovery and early translational research programs in oncology\, autoimmune and neurological indications. \nThe role will involve extensive partnership with scientist colleagues from across Celgene Research & Early Development (R/ED) to drive new experimental\, data capture and sample rescue strategies\, and will include inter-disciplinary collaboration with analytical research colleagues to maximize the depth and robustness of insights derived from transcriptional\, mutational and epigenetic profiling datasets. Areas of technical research focus include the successful profiling of rare\, damaged or low-yield samples\, and collaborative pursuit and assessment of diagnostic assay hypotheses. \nKey stakeholders include researchers in our thematic centers of excellence (TCoEs)\, our Translational Development and Diagnostics (TDD) function\, and colleagues in the Research Informatics and Knowledge Utilization (RIKU) department\, engaged in work towards key objectives for Celgene Research and Early Development (R/ED). \nThis position suits an individual with demonstrated scientific talent and future leadership potential\, with excellent communication and collaboration skills. Keen interest in inter-disciplinary application of high-throughput molecular profiling methods to life sciences data is imperative. \nApplications are encouraged from those looking to impact delivery of truly innovative and life-changing therapies for complex diseases of unmet medical need. \nResponsibilities will include\, but are not limited to\, the following: \n\nCollaborative design and execution of NGS profiling experiments to elucidate disease state and therapeutic response\, with focus on successful profiling of rare\, damaged or low-yield samples\, and collaborative pursuit and assessment of diagnostic assay hypotheses.\nResearch at the leading edge of NGS sample preparation and profiling technologies\, including implementation of novel protocols drawn from the literature\, Celgene academic collaborators\, and/or in-house efforts\, aligned to Celgene scientific research objectives.\nAdvise on sample extraction\, library preparation and QC\, guide collection of supporting metadata\, liaise with computational research colleagues during analytical research\, and translational scientists involved in diagnostics research.\nDesign and perform pilot experiments to test new protocols\, and assess new profiling platforms and external vendor capabilities.\nContribute to the operation of internal next-generation sequencing resources and development of supporting infrastructures\, including documentation of protocols developed and supervision of technical support staff as required.\nPresent strategies\, approaches\, results and conclusions to Celgene colleagues and external audiences to a publishable standard.\nContribute to enable strategic collaborations with academic and commercial collaborators to benefit therapeutic programs.\n\nSkills/Knowledge Required: \n\nPh.D. in biology\, biochemistry or related discipline at a recognized higher-education establishment.\nAt least 6 years of inter-disciplinary research experience with focus on cell or molecular profiling for elucidation of human disease in university\, hospital or biotechnology research scenarios.\nExpertise in performing state of the art NGS studies with demonstrable record of innovative protocol development and peer-reviewed publication in relevant areas.\nExpertise in the generation of robust molecular profiling datasets from low-yield\, damaged or contaminated human samples for translational research objectives. \nExperience in use of NGS profiling methods to answer complex research questions in cancer biology\, autoimmune disease\, epigenetics and/or immune biology.\nHands-on experience of sample and library preparation\, operation and maintenance of high- and low-throughput NGS apparatus (Illumina preferable).\nIn-depth knowledge of contemporary NGS technologies and experimental design considerations\, and familiarity with downstream bioinformatics approaches applied to process\, analyze\, visualize and interpret NGS datasets.\nAwareness of contemporary LIMS schema\, open-source bioinformatics tools and database structures.\nExperience in performing functional assays to validate experimental findings.\nExcellent time management and organizational skills\, proven problem-solving skills\, collaborative nature and adaptability across disciplines
URL:https://ces.b2sg.org/event/celgene2-110ct18/
LOCATION:Celgene San Diego\, 10300 Campus Point Dr\, San Diego\, CA\, 92121\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/png:https://ces.b2sg.org/wp-content/uploads/2017/08/celgene-1-e1503843775806.png
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20181014
DTEND;VALUE=DATE:20181116
DTSTAMP:20260829T171235
CREATED:20181014T192526Z
LAST-MODIFIED:20181014T192526Z
UID:20746-1539475200-1542326399@ces.b2sg.org
SUMMARY:Institute Research Scientist
DESCRIPTION:ECLIPSE (Evolution of Cancer\, Leukemia and Immunity Project) is a novel organization within the MD Anderson Cancer Center\, Houston\, Texas\, with the mission of making MDACC and its partners recognized leaders in the identification and development of innovative immunooncology therapies that will cure all hematologic malignancies. \nThe primary requirement for an individual in this position is an experienced and highly motivated individual with hands-on experience in identification and validation of potential therapeutic targets for patients with advanced hematological malignancies. Such data generated from the team is expected to influence a broad array of decisions around target prioritization and generation of therapeutic modalities against those particular targets. The successful candidate will participate in cross-functional research to design and develop novel assays that will support an understanding of target biology. The selected candidate will be expected to work at the bench and contribute to development and implementation of potential biomarker strategies to support clinical development. Previous experience in biotech/pharma is highly preferred. \n\nKey Functions \n· Design and develop key experiments contributing to the conception\, execution\, and championing of novel targets\, technology platforms\, and strategies related to the development of biologics-based clinical candidate programs. \n· Provide expert technical guidance to others on project/task groups. Determine priorities and communicate to the team. Redirect operations as necessary to achieve objectives. \n· Collaborate with team members on a discovery platform using high throughput multi-omic technologies and apply scientific expertise in immunology and cancer biology to drive these programs in a multidisciplinary and exciting research team environment. \n· Interface with scientific staff both within the institution and outside\, including industry collaborators\, external consultants and stakeholders. \n· Commitment to keep abreast of current and emerging technological and scientific advancements in the field. \nEducation \nRequired: Bachelor’s degree in Biology\, Biochemistry\, molecular biology\, cell biology\, enzymology\, pharmacology\, chemistry or related field.\n\nPreferred: PhD in Biochemistry\, Molecular Biology or a related discipline.\n\nExperience\nRequired: Ten years of relevant research laboratory experience. With Master’s degree\, eight years of required experience and with PhD\, two years of required experience.\n\n· Experience with genetic (ie RNAi and CRISPR) and pharmacological (i.e. small molecule inhibitors or antibodies) approaches to study target biology utilizing state of the art molecular biology and biochemistry methods and assays.\n\n· Hands-on experience in standard in vitro and in vivo cell biology and immunology assays including\, but not limited to\, expansion of CTLs\, tetramer assays\, cytotoxicity assay\, functional assays like ADCC\, ADCP etc. is highly desirable. \n· Broad knowledge of cell culture techniques is required and knowledge of in vivo oncology models is desirable. \n· Extensive knowledge and experience in key areas of tumor biology such as oncogenic signaling\, tumor microenvironment\, tumor immunology\, metabolism\, epigenetic deregulation or anti-apoptosis as evidenced by publication in peer-reviewed journals. \n· Strong data analysis skills\, ability to interpret results and contribute to the design of follow-up experiments\, troubleshoot issues with assay performance. \n· Ability to effectively present results and conclusions to co-workers\, collaborators and senior leadership. \n· Ability to approach problems with curiosity and open mindedness; offer new ideas\, solutions and/or options. Notice current processes/products needing improvement and generate new options using own technical expertise and by utilizing multiple resources. \n· Ability to effectively challenge others in a group to identify creative approaches. \n· Ability to ensure scientific excellence\, quality and completeness of programs. \n· Strong knowledge of translational immunology such as identification of targets for immunotherapy in solid tumors and/or leukemia. \n· Excellent computer skills with working knowledge of commonly used research software programs.
URL:https://ces.b2sg.org/event/mdacc-14oct18/
LOCATION:MD Anderson Cancer Center\, 1515 Holcombe Blvd\, Houston\, TX\, 77030\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/05/MDAnderson.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20181015
DTEND;VALUE=DATE:20181117
DTSTAMP:20260829T171235
CREATED:20181015T065008Z
LAST-MODIFIED:20181015T065008Z
UID:20748-1539561600-1542412799@ces.b2sg.org
SUMMARY:Scientist II
DESCRIPTION:The key therapeutic platforms currently under investigation leverage a broad range of biological activities that allow for the development of novel paradigm-changing therapeutics. Our discovery research teams are organized into four Thematic Centers of Excellence (TCoE)\, including Protein Homeostasis (PH)\, Epigenetics\, Immuno-oncology and Inflammation & Immunology. Within each these areas\, discovery research\, translational research\, and early clinical development are integrated into a single team.  \nSummary/Scope:\nThe PH TCoE is built on our legacy IMiD drugs\, which exhibited therapeutic efficacy in erythema nodosum leprosum\, myelodysplastic syndrome\, and multiple myeloma. This class of drugs hijack the cereblon E3 ubiquitin ligase to eliminate disease-driving proteins that are otherwise considered “undruggable”. The early drug discovery team in the PH TCoE is now seeking a motivated PhD scientist to assist the development of cereblon modulating agents that target novel cereblon neosubstrates for ubiquitination and degradation for the treatment of a variety of human diseases. The successful candidate will develop and utilize state-of-art biotechnology tools to identify novel substrates and perform target validation for the relevant disease indication. The successful candidate will work collaboratively in a multi-disciplinary environment\, and w ill have the opportunity to work closely with discovery project teams and scientists across the PH TCoE functional areas and to present his or her work at project team meetings and to the senior research leadership.  \nResponsibilities will include\, but are not limited to\, the following:  \nGenerate testable hypotheses\, design research protocols and execute experiments \nLead genome-wide and focused CRISPR screens \nUtilize CRISPR and RNAi to determine the disease relevance of novel cereblon substrates \nPerform cellular experiments to help define the SAR of cereblon modulators \nUtilize genetic and pharmacological approaches to define the MOA of candidate agents \nDesign and develop novel assays \nDocument\, interpret and troubleshoot results \nConvey data analysis and interpretation to supervisor and colleagues \nCommunicate with peers and supervisors and foster teamwork \nContribute to collaborative efforts \nStrong commitment to quality and reproducibility \nDemonstrate adaptability \nSupervise or guide research staffs  \nQualifications:\nPh.D. in Molecular and Cell Biology\, Biochemistry or related scientific discipline with at least 4 years of relevant work experience. Strong publication record in major scientific journals is required.  \nSkills/Knowledge Required :\nExtensive wet-lab experience with routine molecular\, cellular and genetic biology tools \nExperience with CRISPR-Cas9 mediated gene editing \nExperience with genome-wide CRISPR screens is preferred \nExtensive training in cancer biology \nResearch experience in hematologic malignancies is preferred \nHighly motivated and strong team player with a high degree of independence \nInnovative and critical thinking \nExcellent time management and organizational skills \nStrong communication skills\, both written and oral 
URL:https://ces.b2sg.org/event/celgene-15oct18/
LOCATION:Celgene San Diego\, 10300 Campus Point Dr\, San Diego\, CA\, 92121\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/png:https://ces.b2sg.org/wp-content/uploads/2017/08/celgene-1-e1503843775806.png
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20181016
DTEND;VALUE=DATE:20181118
DTSTAMP:20260829T171235
CREATED:20181016T074417Z
LAST-MODIFIED:20181016T074417Z
UID:20750-1539648000-1542499199@ces.b2sg.org
SUMMARY:Postdoctoral Fellow
DESCRIPTION:We seek a highly motivated scientist to fill a postdoctoral position in the Department of Dermatology at Boston University School of Medicine to study the role of epigenetic changes in tumor progression. The postdoctoral associate will lead multidisciplinary projects aimed at understanding the epigenetic basis for skin cancer and other skin diseases. The candidate will design\, execute\, and interpret research involving cutting-edge techniques and fundamental molecular and cellular biology research tools to investigate the role of epigenetic alterations in the biology of human melanoma. \n\nThis project will involve the use of standard molecular and cellular biology techniques in addition to more novel techniques associated with epigenetic studies including chromatin immunoprecipitation assays (ChIP) and ChIP-seq as well as comprehensive gene expression analyses\, molecular manipulations of target gene expression using viral vectors\, and functional analyses in mouse disease model. \nRequired Skills \nWe seek qualified individuals who are highly motivated\, flexible\, collaborative\, detail-oriented\, and possess a strong commitment to research excellence. The successful candidate should have a PhD with a strong background in molecular biology\, cell biology\, chromatin biology\, genomics\, and/or biochemistry. Research experience in bioinformatics skills and animal models would be advantageous. The postdoctoral associate is expected to have a strong work ethic\, critical thinking abilities\, and excellent organization and communication skills. Previous training in cancer biology and epigenetic molecular techniques is preferred but not a requirement. \n\nInterested applicants should submit a letter of application\, CV\, and references to: \n\nRhoda M. Alani\, MD\nHerbert Mescon Professor and Chair \nDepartment of Dermatology\nBoston University School of Medicine\n609 Albany St.\, Suite J-507\nBoston\, MA 02118\njlondon@bu.edu
URL:https://ces.b2sg.org/event/boston-16oct18/
LOCATION:Boston University\, Boston\, MA\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/12/boston-uni.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20181017
DTEND;VALUE=DATE:20181119
DTSTAMP:20260829T171235
CREATED:20181017T052539Z
LAST-MODIFIED:20181017T052539Z
UID:20752-1539734400-1542585599@ces.b2sg.org
SUMMARY:Research Associate
DESCRIPTION:We are seeking a Research Associate to study transcriptional and epigenetic regulation of gene expression in breast cancer. The Zhang laboratory currently focuses on elucidating molecular mechanisms of gene- and tissue- specific transcriptional cofactors in breast cancer [Mol Cell 19:89-100\, PNAS 107: 6765\, JBC 286:17746\, EMBO J. 30:2405\, Cancer Research 72:5625\, ACS Nano 11(1):335\, Cancer Research 78(2):422]. We are using a combination of biochemical\, molecular\, genomic (RNA-seq\, ChIP-seq) and mouse genetic (conditional knockout\, mutant knockin and overexpression) approaches. We are also currently developing RNA-based nano-therapeutics to target these cofactors to overcome therapeutic resistance of human breast cancer. \n\nMinimum Qualificaitons: Bachelor degree in a profession/field or equivalent level of knowledge \n\nPreferred Qualifications: PhD and/or MD degree with research experience in biochemistry\, molecular cellular biology or a related field. Prior experience with animal studies\, immunology\, RNA-seq/ChIP-seq analyses or nanotechnology is a plus.
URL:https://ces.b2sg.org/event/cinn-17oct18/
LOCATION:University of Cincinnati\, 2600 Clifton Ave\, Cincinnati\, OH\, 45220\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/06/uni-cincinnati.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20181018
DTEND;VALUE=DATE:20181120
DTSTAMP:20260829T171235
CREATED:20181018T031438Z
LAST-MODIFIED:20181018T031438Z
UID:20756-1539820800-1542671999@ces.b2sg.org
SUMMARY:Postdoctoral Research Fellow
DESCRIPTION:A postdoctoral position is available in the MacPherson Lab at Fred Hutchinson Cancer Research Center. The project will focus on small cell lung cancer (SCLC)\, a neuroendocrine tumor type that exhibits initial sensitivity to chemotherapy but invariable emergence of chemoresistance. Our lab is interested in linking specific gene mutations in SCLC to therapeutic vulnerabilities and to chemoresistance. We have developed a panel of new genetically engineered mouse models (e.g. see Jia et al\, 2018 Cancer Discovery) and patient derived xenograft models that can be used in these efforts. Many projects in the lab incorporate genome-wide functional screens in cells and in vivo. These screens are used to identify functionally important genes for SCLC and genetic vulnerabilities that might lead to new avenues to therapeutically target SCLC. One available project includes interrogating the importance of candidate SCLC driver genes and linking specific SCLC-mutated genes to novel therapeutic approaches. Hits identified through functional screens are followed by therapeutic studies that employ GEM and PDX model. A second available project applies in vivo genome-wide screens to understand drivers of chemoresistance.\n\n\n\nQualifications\n\n\n\nWe are looking for a highly motivated individual with a PhD or MD and interests in cancer genetics\, epigenetics\, mouse models\, functional screening and/or therapeutics. The candidate should be able to drive an individual project but also be highly collaborative. A strong foundation in molecular and cell biology is essential. The candidate should be independent\, enthusiastic and scientifically rigorous. \nPlease include a cover letter detailing your research interest and suitability for this position and names of at least two references with your application.
URL:https://ces.b2sg.org/event/hutch-18oct18/
LOCATION:Fred Hutchinson Cancer Research Center\, 1100 Fairview Ave. N.\, Seattle\, WA\, 98109-1024\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/png:https://ces.b2sg.org/wp-content/uploads/2016/07/fred_hutch.png
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20181019
DTEND;VALUE=DATE:20181121
DTSTAMP:20260829T171235
CREATED:20181019T172124Z
LAST-MODIFIED:20181019T172124Z
UID:20758-1539907200-1542758399@ces.b2sg.org
SUMMARY:Investigator – Cancer Therapeutics
DESCRIPTION:We are seeking a highly creative\, self-motivated\, and collaborative investigator to join the Cancer Therapeutics department at GNF. The ideal candidate will have a deep understanding of cancer biology and will be adept in cell biology\, biochemistry\, and/or drug discovery approaches. Experience in a matrixed\, fast-paced industry environment and/or experience with cutting-edge discovery technologies\, such as ELISA/MSD\, Western/Wes/protein analyses\, enzymatic assays\, PCR approaches\, CRISPR\, bioinformatics\, epigenetics\, phenotypic screening\, and ex vivo tumor/tissue analyses\, is highly desirable. Also highly desirable is experience working with different therapeutic modalities including small molecules as well as biologics including antibodies\, peptides\, and/or drug conjugates. The successful candidate will work independently and in collaboration with multifunctional teams to design and execute experiments\, analyze and present data\, and propose novel targets and approaches\, with focus and expertise in in vitro biology. \nPrimary responsibilities: \n\nDesign\, execute\, and analyze in vitro and ex vivo biology experiments to discover and validate new targets and therapeutics for cancer\nServe as the biology lead on drug discovery and platform development projects\nPresent project data and plans to stakeholders within GNF and the broader NIBR/Novartis organization\nMay supervise BS-/MS-level associates
URL:https://ces.b2sg.org/event/novartis-19oct18/
LOCATION:Novartis (CA)\, San Diego\, CA\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/png:https://ces.b2sg.org/wp-content/uploads/2017/09/novartis.png
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20181020
DTEND;VALUE=DATE:20181122
DTSTAMP:20260829T171235
CREATED:20181020T081914Z
LAST-MODIFIED:20181020T081914Z
UID:20761-1539993600-1542844799@ces.b2sg.org
SUMMARY:Postdoctoral Scientist
DESCRIPTION:A Postdoctoral Scientist position is available for a skilled and motivated scientist in the Laboratory of Dr. Maho Shibata in the Department of Anatomy and Cell Biology and the Cancer Center at the George Washington University School of Medicine and Health Sciences. \nDr. Shibata’s lab applies concepts from developmental biology and stem cell biology to prostate cancer research. The lab uses genetically engineered mouse models\, explant cultures\, and 3D organoid culture systems to study androgen signaling during prostate development\, and to identify novel molecular drivers of castration-resistant prostate cancer. There are multiple project possibilities. \nDuties include: \n\nIndependently design experiments\, collect and analyze data\, and assist collaborators\nPresent findings in group meetings and internal and external scientific meetings\nPrepare and submit postdoctoral fellowship applications\nWrite and publish research manuscripts\nSupervise and train students\nPerform other duties as assigned. The omission of specific duties does not preclude the supervisor from assigning duties that are logically related to the position.\n\n\n\nMinimum Qualifications: \nQualified candidates will hold a PhD in a related discipline. Degree must be conferred by the start date of the position. \nAdditional Required Licenses/Certifications/Posting Specific Minimum Qualifications: Preferred Qualifications: \nPhD experience in one or more of the following: cancer biology\, mouse development\, mouse genetics\, stem cell biology\, epigenetics\, computational biology\nAt least 1 first author peer-reviewed publication
URL:https://ces.b2sg.org/event/gwu-20oct18/
LOCATION:George Washington University\, 2121 I St NW\, Washington\, DC\, 20052\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/05/gwu-1.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20181022
DTEND;VALUE=DATE:20181124
DTSTAMP:20260829T171235
CREATED:20181022T184816Z
LAST-MODIFIED:20181022T184855Z
UID:20763-1540166400-1543017599@ces.b2sg.org
SUMMARY:Postdoctoral Research Associate
DESCRIPTION:The Souroullas Lab studies the role of chromatin dynamics during cancer development\, with a specific focus on hematopoietic (lymphoid) malignancies and melanoma. Recent next-generation sequencing studies have highlighted the role that epigenetic modifiers play in cancer\, however\, our understanding of these mechanisms remains quite rudimentary. We have recently demonstrated the oncogenic and neomorphic activity of mutations in the EZH2 gene\, part of a protein complex which mediates histone methylation and regulates gene expression (Souroullas et. al.\, Nature Medicine\, 2016). The underlying mechanisms of the oncogenic activity of these mutations\, however\, remain unresolved. Research opportunities are therefore available for highly motivated individuals with an interest in cancer genetics and/or epigenetics. Projects include\, but are not limited to\, the study of genetic interactions using mouse models\, molecular analysis of epigenetic crosstalk\, and the effects of these mutations on the tumor immune response. Investigation of these studies involves the use of state-of-the-art mouse genetics\, functional genomics\, next-generation sequencing\, bioinformatics\, molecular biology\, and tumor biology and hematopoiesis. \nFor additional information about our lab\, please visit our website at: https://sites.wustl.edu/souroullaslab \nThe appointment is viewed as a training or transitional period preparatory to an academic\, industrial\, governmental\, or other full-time research or teaching career. Used when the appointee performs specific services on a grant or contract in exchange for compensation. The appointment is of limited duration generally\, not to exceed five years cumulatively unless there are extenuating circumstances. \nPRIMARY DUTIES AND RESPONSIBILITIES: \nTrains under the supervision of a faculty mentor including (but not limited to): \n\nManages their own project\, which should lead to several first author publications.\nDevelops proficiency in their chosen scientific discipline/field.\nDevelops proficiency in their technical skills.\nDevelops proficiency in their ancillary skills\, e.g. writing\, public speaking\, networking\, critical evaluation of scientific documents\, etc.\nPresents scientific work both inside and outside the University.\nAssists with grant preparation and reporting.\nPrepares and submits papers on research.\nAssists in the design of research experiments.\nEvaluates research findings and assists in the reporting of the results.\nConscientious discharge of his/her research responsibilities.\nMaintain conformity with ethical standards in research.\nMaintain compliance with good laboratory practice including the maintenance of adequate research records.\nEngage in open and timely discussion with his/her mentor regarding possession or distribution of material\, reagents\, or records belonging to their laboratory and any proposed disclosure of findings or techniques privately or in publications.\nCollegial conduct towards co-trainees\, staff members and members of the research group.\nAdherence to all applicable University policies\, procedures and regulations. All data\, research records and materials and other intellectual property generated in University laboratories remain the property of the University.\n\n\n\n\n\n\n\n\nRequired Qualifications\n\n\n\n\n\n\n\n\nA recent Ph.D or M.D/Ph.D in the biomedical sciences\, and a record of productive research with at least one first author publication in a peer reviewed journal.\n\n\n\n\n\n\n\n\nPreferred Qualifications\n\n\n\n\n\n\n\n\nPrior experience with mouse models and bioinformatics analysis is a plus but not required.\nDemonstrated ability to perform independent research in biomedical sciences and published results in peer reviewed journals.
URL:https://ces.b2sg.org/event/wustl-22oct18/
LOCATION:Washington University School of Medicine in St. Louis\, 660 S Euclid Ave\, St. Louis\, MO\, 63110\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2018/03/WUSTL-washington-uni-st-louis.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20181023
DTEND;VALUE=DATE:20181125
DTSTAMP:20260829T171235
CREATED:20181023T064927Z
LAST-MODIFIED:20181023T064927Z
UID:20766-1540252800-1543103999@ces.b2sg.org
SUMMARY:Research Fellow
DESCRIPTION:The successful candidate will join the Epigenetic Etiology of Human Disease Laboratory to study the role of DNA epigenetic modifications in human disease. More specifically\, he/she will examine how DNA methylating and hydroxymethylating enzymes regulate their respective DNA epigenetic modifications and how these marks regulate expression and genome stability\, and interface with other epigenetic modifications. Disease focus area of the laboratory include cancer (hepatocellular and renal)\, obesity\, and diabetes. Specific research areas include application of genome-wide epigenomics methods to decipher DNA methylation/hydroxymethylation defects in cancer and biochemical/cell culture-based techniques to study the regulation and interactions between chromatin remodeling factors (e.g. DNMTs\, TETs\, HMTases). Techniques commonly used in the laboratory include: quantitative RT-PCR\, western blotting\, tissue culture\, transfections\, bisulfite sequencing\, pyrosequencing\, ChIP-qPCR\, ChIP-seq\, next-gen library preparation and sequencing\, Infinium 450k arrays\, bioinformatics analysis\, and biochemical analysis of protein function. Experience in one or more of these areas is a plus. The candidate will play a major role in the preparation of manuscripts that arise from this work and devote 100% effort to these tasks (no patient contact or other responsibilities). \nA Research Fellow at Mayo Clinic is a temporary position intended to provide training and education in research. Individuals will train in the research program of a Mayo Clinic principal investigator. Qualified individuals will demonstrate the potential for research as evidenced by their training and peer-reviewed publications and should become competitive for national research grants. Proof of English proficiency is required for J-1 Short-Term Scholars\, Research Scholars\, Professors\, Specialists\, and Student Interns sponsored by Mayo Clinic. Please attach the following required documents at the time of application. \n\n\n\n\n\nCurrent curriculum vitae and bibliography\n\nThree letters of recommendation\, signed\, on letterhead\, describing:\nRelationship to the applicant.\nPast work/academic performance.\nWork qualities/personal conduct.\n\n\nOverall assessment of potential for success in research environment.\nDoctoral degree certification\, if applicable:\n\nOriginal or notarized copy of diploma or final transcript issued by school (English translation required).\n\n\n\n\n800146; J2WRTP\n\n\nQualifications \nMust have a Ph.D.\, M.D.\, or equivalent doctoral degree in a field deemed relevant by the program. Research Fellow is appropriate for individuals who have completed no more than one prior postdoctoral fellowship\, at Mayo Clinic or elsewhere. \nAdditional qualifications \nPlease attach the following required documents at the time of application: \n\nCurrent curriculum vitae and bibliography\nThree letters of recommendation\, signed\, on letterhead\, describing:\n\nRelationship to the applicant.\nPast work/academic performance.\nWork qualities/personal conduct.\nOverall assessment of potential for success in research environment.\n\n\nDoctoral degree certification\, if applicable:\nOriginal or notarized copy of diploma or final transcrip
URL:https://ces.b2sg.org/event/mayo-23oct18/
LOCATION:Mayo Clinic\, 200 1st St SW\, Rochester\, MN\, 55905\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/png:https://ces.b2sg.org/wp-content/uploads/2017/08/mayo-clinic_416x416.png
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20181024
DTEND;VALUE=DATE:20181204
DTSTAMP:20260829T171235
CREATED:20181024T091043Z
LAST-MODIFIED:20181024T091043Z
UID:20768-1540339200-1543881599@ces.b2sg.org
SUMMARY:Faculty Positions - Cancer Research
DESCRIPTION:The UNC Lineberger Comprehensive Cancer Center\, in collaboration with departments in the School of Medicine and across the entire University of North Carolina Chapel Hill\, seeks outstanding candidates for faculty positions at all ranks in basic and translational cancer research.  \n  \nThis broad-based recruitment seeks creative scientists in areas\, including but not limited to: animal models and therapy\, signal transduction\, computational and systems biology\, cancer genetics and precision medicine\, tumor virology\, drug development and target validation\, epigenetics and gene expression\, DNA damage and repair\, tumor immunology\, inflammation and cancer\, and stem cells.  \n  \nApplicants should have a strong record of recent accomplishments as a post-doctoral fellow or sustained productivity as an established faculty member. Appointment and rank in an academic department will be determined by the applicant?s qualifications. Applications will be reviewed beginning December 3\, 2018\, and until the positions are filled.  
URL:https://ces.b2sg.org/event/nc-24oct18/
LOCATION:University of North Carolina – UNC-Chapel Hill\, Chapel Hill\, NC\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2018/07/unc-chapel-hill-north-caro-nc.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20181026
DTEND;VALUE=DATE:20181128
DTSTAMP:20260829T171235
CREATED:20181026T084747Z
LAST-MODIFIED:20181026T084815Z
UID:20771-1540512000-1543363199@ces.b2sg.org
SUMMARY:Postdoctoral Associate
DESCRIPTION:Our group is interested in the functional genetics of cancer. We use state of the art technology in genomics\, proteomics and epigenetics to understand the molecular mechanisms that drive cancer progression\, metastasis and chemoresistance. We are recruiting a postdoctoral fellow to work on understanding the functional consequences of combinations of mutations that contribute to tumorigenesis. Highly self-driven\, ambitious candidates with a knack for solving challenging problems in cancer biology and outstanding publication track record are encouraged to apply. The candidate is expected to work as a part of multi-disciplinary\, dynamic and vibrant team\, and will have the opportunity to work and develop his/her research program with the best in the field. \nRequired Skills \nRequired Experience \nEducation and/or Experience: \nYou hold a PhD degree or equivalent in bioinformatics\, statistics\, computational biology\, or related discipline of biomedical research. Experience in computational and statistical genetics\, genomics and knowledge of R and PERL and their application in cancer research is mandatory. Programming experience is required as is having worked with big data. It is desired that you are familiar with standard molecular biology\, tissue culture practices and mouse genetics protocol. The successful candidate will have strong qualifications or experience within several of the following areas: \n\nBioinformatics and systems biology at the molecular level\nCancer pathophysiology and RNA biology of Cancer.\nProject management of interdisciplinary research projects within genomics and bioinformatics (Genomics\, Non-coding RNAs\, Proteomics and Chromatin Biology)\nExperience with data structures\, databases\, and data architectures (TCGA\, SU2C etc)\nKnowledge of biomedical resources and infrastructures
URL:https://ces.b2sg.org/event/sbp-26oct18/
LOCATION:Sanford Burnham Prebys Medical Discovery Institute\, 10901 N Torrey Pines Rd\, La Jolla\, CA\, 92037\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/06/sanford-burham-sbp.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20181027
DTEND;VALUE=DATE:20181129
DTSTAMP:20260829T171235
CREATED:20181027T102734Z
LAST-MODIFIED:20181027T102915Z
UID:20774-1540598400-1543449599@ces.b2sg.org
SUMMARY:Associate Scientist
DESCRIPTION:The Obeng Lab is seeking a highly motivated\, team-oriented\, and creative Associate Scientist to join them as an integral part of the St. Jude research community. The focus of the Obeng Lab is myeloid malignancies. We are specifically interested in how acquired mutations in hematopoietic stem cells block mature blood cell differentiation and/or cause leukemic transformation. We are using a variety of in vivo and in vitro model systems to study the functional consequences of RNA splicing factor and epigenetic modifier mutations on stem cell function and to identify new targeted therapies for myeloid diseases. Successful applicants will respond well to a busy and dynamic lab environment and possess the skills to diligently manage both experiments and personnel within the laboratory. They will possess strong organizational and communication skills. This position requires expertise in molecular biology\, cell culture\, colony management\, and next generation sequencing. The ideal candidate must be able to design and perform experiments with minimal supervision and be interested in learning and applying new techniques from the literature. A background in hematopoiesis research is a plus. \nWhen you work at St. Jude you enjoy: \nConstant learning: From state-of-the-art resources and core facilities to world-class seminars and symposia\, you’ll be given constant opportunities to expand your knowledge\, learn new skills\, and grow in your career. \nResearch that translates: Your work at St. Jude directly impacts patient care and advances discoveries to improve cancer treatment worldwide. \nStability and growth: Thanks to generous donors and supplemental grant support\, our scientific progress is never halted and you’ll enjoy unmatched resources to do the science you’ve always dreamed of doing. \nMinimum Education\n\nBachelor’s degree in an appropriate scientific field is required.\n\nMinimum Experience\n\nA minimum of fifteen (15) years of relevant post-degree work experience is required with a Bachelor’s degree\, with at least seven (7) years at the Research Lab Specialist level\nA minimum of fourteen (14) years of relevant post-degree work experience is required with a Master’s degree\, with at least seven (7) years at the Research Lab Specialist level\nA minimum of nine (9) years of relevant work experience including post-doctoral and/or technical staff experience is required with Ph.D.\nNOTE: BS/MS level staff at Research Lab Specialist level as of 05/12/2003 could be considered for promotion to Associate Scientist after seven (7) years as a St. Jude Research Lab Specialist or an equivalent position in a similar research environment.
URL:https://ces.b2sg.org/event/stjude-27oct18/
LOCATION:St. Jude Children’s Hospital\, 262 Danny Thomas Pl\, Memphis\, TN\, 38105\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/05/stjude.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20181029
DTEND;VALUE=DATE:20181201
DTSTAMP:20260829T171235
CREATED:20181029T081957Z
LAST-MODIFIED:20181029T081957Z
UID:20778-1540771200-1543622399@ces.b2sg.org
SUMMARY:Principal Scientist
DESCRIPTION:We seek an accomplished Principal Scientist level oncologist/immunologist to join the in vivo pharmacology group within the Oncology Research Unit (ORU) of Pfizer’s Worldwide Research & Development (WRD) division in La Jolla\, California. The successful candidate will join a dynamic team of scientists in the Oncology In Vivo Pharmacology Group\, playing a leading role in the development of models of cancer and evaluating new drug candidates. \n\nParticipate in pre-clinical drug discovery and development projects with a focus on targeted therapeutics\, epigenetics and immune-oncology. Characterize and develop small molecules in close collaboration with partner lines as an integral member of drug discovery teams. Evaluate anti-tumor effects in combination with biologics. Employ and develop new cutting-edge in vivo mouse and human cancer models. Provide technical and scientific expertise in in vivo pharmacology to the tumor cell biology department to enable target identification\, validation\, prioritization and efficient drug discovery of small molecules. Ideal applicants will possess excellent communication\, leadership and organizational skills\, critical problem-solving abilities\, and a commitment to excellence. \n\nROLE RESPONSIBILITIES \n\nEstablish scientific in vivo strategy for drug discovery projects.\nServe as the in vivo pharmacology lead for several drug discovery projects. Work within multi-functional teams to support small molecule drug discovery and combination therapy.\nDevelop and characterize new in vivo mouse models\, including syngeneic tumor and genetically engineered mouse (GEM) models\, to study biologic mechanisms and support exploration of novel cancer immune therapeutics and targeted therapies.\nDesign and conduct in vivo studies to evaluate and establish efficacy\, PK/PD relationship\, combination strategy\, biomarker identification and analysis.\nSupervision and scientific guidance of 3-5 experienced scientists.\nInterpretation\, presentation and documentation of experiments as well as preparation of reports. Responsible for in vivo section of i.e. IND filings.\nWritten and verbal presentation of results within a multidisciplinary team environment. Ensure that projects have all critical in vivo data to enable project stage dependent decisions.\nPublication of results in scientific peer-reviewed journals and presentations at internal\, national\, and international meetings.\n\n\nQUALIFICATIONS \n\nPh.D. in Cancer Biology\, Immunology\, Biochemistry\, Genetics or equivalent experience in a related discipline.\nPreferred > 5 years industry experience\nExpertise in in vivo pharmacology and experience with animal models of human cancers as well as strong publication record or evidence of equivalent achievements in industry are desired.\nHands on in vivo skills (IV\, PO dosing)\, blood/tissue collection\nProven ability to make important contributions to cancer biology\, immuno-oncology or related fields\nAbility to follow novel scientific or technological developments\, and to implement them in the laboratory.\nCurrent knowledge of oncology research\, drug discovery and development\, with emphasis on drug combinations\, immuno-oncology.\nTechnical and scientific experience in drug discovery and preclinical development.\nExcellent written and oral communication and presentation skills in English. Proficiency in all common office and scientific software.\nStrong ability to multi-task and work productively in a fast-paced\, highly collaborative\, and diverse team environment. Capability to contribute to a vivid and challenging intellectual environment.\n\n\nA plus: \n\nExperience in leading Oncology drug discovery programs\nSupervisory experience\nExperience in immune-modulatory research\, flow cytometry\nExpertise with GEM and humanized models\nExperience with biomarker development
URL:https://ces.b2sg.org/event/pfizer-29oct18/
LOCATION:Pfizer – La Jolla\, CA\, 10350 N Torrey Pines Rd\, La Jolla\, CA\, 92037\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2018/05/pfizer_new_logo.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20181030
DTEND;VALUE=DATE:20181203
DTSTAMP:20260829T171236
CREATED:20181030T090035Z
LAST-MODIFIED:20181030T090330Z
UID:20780-1540857600-1543795199@ces.b2sg.org
SUMMARY:Post-Doctoral Research Fellow
DESCRIPTION:A postdoctoral fellowship position is available in the Grady laboratory at FHCRC for a NCI (RO1)-funded translational cancer research program. The incumbent will be part of the multi-disciplinary research team to identify and characterize novel molecular/cellular mechanisms driving colon cancer initiation and progression using cutting-edge technology and state-of-the-art instrumentation. The focus of research conducted in Dr. William Grady’s laboratory is the study of the molecular and cell biology of gastrointestinal cancer as well as the role of genetic and epigenetic alterations in cancer.\n\n\n\nQualifications\n\n\n\nHighly motivated candidates are encouraged to apply.\n\nThe successful candidate will have a PhD in cellular biology\, molecular biology\, biochemistry or a related field with strong interest in cancer research.\nA track record of excellent first author publication is strongly favored.\nEstablished experience in the areas of aging/senescence is desirable.\nEstablished experience with CRISPR-Cas9 gene editing technology in primary cell culture/3-D organoid culture is a plus.\nWorking knowledge/experience with next-gen sequencing is a plus.\n\nOther key abilities:\n\nAbility to work independently and cooperatively\nStrong communication skills and interpersonal skills\nWillingness to teach junior lab members\n\nTo be considered\, the application should include a resume with at least three references\, and a summary of research experience and interests.
URL:https://ces.b2sg.org/event/fred-30oct18/
LOCATION:Fred Hutchinson Cancer Research Center\, 1100 Fairview Ave. N.\, Seattle\, WA\, 98109-1024\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/png:https://ces.b2sg.org/wp-content/uploads/2016/07/fred_hutch.png
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20181031
DTEND;VALUE=DATE:20181203
DTSTAMP:20260829T171236
CREATED:20181031T091636Z
LAST-MODIFIED:20181031T091636Z
UID:20782-1540944000-1543795199@ces.b2sg.org
SUMMARY:Postdoctoral Scholar
DESCRIPTION:kentTwo Postdoctoral or Visiting Scholar positions are available to (1) study the mechanism of breast cancer metastasis and develop novel therapeutic strategies for treating metastatic breast cancer; and (2) investigate the epigenetic mechanisms of chemical carcinogenesis. These projects will use cell culture and mouse models to investigate the epigenetic mechanisms (DNA methylation\, histone posttranslational modifications and non-coding RNAs) of breast cancer metastasis and chemical carcinogenesis. Candidates should have a recent Ph.D. degree with strong background in cell/molecular biology and cancer biology. Experiences in studies on cancer epigenetics\, non-coding RNAs\, and cancer stem cells with skills in handling mice\, producing tumors in mice and treating mice with commonly-used drug administration approaches would be advantageous. The expected qualifications of candidates include: be highly self-motivated with strong interest in learning new knowledge and techniques; have excellent communication and organizational skills and attention to details\, be capable of conceptualizing\, designing experiments and conducting studies independently as well as cooperatively with other lab members as a team; and have the capability to write manuscripts for quality publications. Compensations including salary and benefits will be highly competitive depending upon candidates’ qualifications. Interested applicants\, please send a cover letter describing your research training experience\, a brief statement of your research interest\, scientific achievements and future career goal\, curriculum vitae (CV) and contact information (names\, e-mails\, and telephone numbers) of three references to: Dr. Zhishan Wang (zhishan.wang@uky.edu) or Dr. Chengfeng Yang (chengfeng.yang@uky.edu)\, Department of Toxicology and Cancer Biology\, University of Kentucky\, Lexington\, KY 40536. Only short-listed applicants will be contacted for interview. \n\nRequired Documents: Curriculum Vita\, Cover Letter\, Writing Sample\, Academic Transcripts\, for Specific Request 1\, please supply a copy of your PhD diploma & English translation if not in English\, and for Specific Request 2\, please submit a written document of your future career goals. \n\n\n\nSkills / Knowledge / Abilities\n\nExperiences in studies on cancer epigenetics\, non-coding RNAs\, and cancer stem cells with skills in handling mice\, producing tumors in mice and treating mice with commonly-used drug administration approaches would be advantageous. The expected qualifications of candidates include: be highly self-motivated with strong interest in learning new knowledge and techniques; have excellent communication and organizational skills and attention to details\, be capable of conceptualizing\, designing experiments and conducting studies independently as well as cooperatively with other lab members as a team; and have the capability to write manuscripts for quality publications. \n\n\n\n\n\nPreferred Education/Experience\n\nPhD\, 0-2 year postdoctoral level research experience
URL:https://ces.b2sg.org/event/ky-31oct18/
LOCATION:University of Kentucky\, 410 Administration Drive\, Lexington\, KY\, 40506\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/06/Univ.-of-Kentucky-logo-e1508082584777.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20181101
DTEND;VALUE=DATE:20181203
DTSTAMP:20260829T171236
CREATED:20181101T152022Z
LAST-MODIFIED:20181101T152022Z
UID:20784-1541030400-1543795199@ces.b2sg.org
SUMMARY:Postdoctoral Associate (Cancer Research)
DESCRIPTION:The laboratory of Dr. Enrique Mesri at the University of Miami Miller School of Medicine’s Department of Microbiology and Immunology and the Tumor Biology Program of Sylvester Comprehensive Cancer Center\, in collaboration with a multidisciplinary team led by Dr. Michael Samuels of the Department of Radiation Oncology\, has an exciting opportunity for a Postdoctoral Associate with relevant experience. This position will lead a project evaluating key viral\, genomic\, and epigenetic correlates of clinical presentation and outcomes of HPV-associated oropharynx cancer. Work includes\, but is not limited to\, analysis of tumor samples and biological fluids derived from ongoing clinical studies. \nThe minimum qualifications for this position are as follows: Ph.D.\, M.D.\, or other doctoral level degree in a related field of life science study. Possess a strong background and first author publication(s) in cancer biology\, virology\, molecular and cellular biology\, or a closely related field of study. Prefer experience working with cell\, animal\, or clinical models in virally induced human cancers. Applicants with experience\, or who are familiar with bioinformatic tools (particularly next generation sequencing data analysis)\, are encouraged to apply. Must be goal-oriented\, proactive\, and hardworking with excellent organizational skills and a passion for making a difference in cancer research. Ability to manage day-to-day operations of the laboratory\, mentoring new staff\, and assisting senior researchers in their presentation and funding efforts. A highly motivated individual is sought who can work effectively in a team as well as independently. Applicants should upload a CV when applying that contains a cover letter\, references\, and complete list of publications\, including representative publications as part of the CV.
URL:https://ces.b2sg.org/event/umiami-1nov18/
LOCATION:University of Miami\, 1320 S Dixie Hwy\, Coral Gables\, FL\, 33146\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/07/u-miami-health.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20181102
DTEND;VALUE=DATE:20181204
DTSTAMP:20260829T171236
CREATED:20181102T072522Z
LAST-MODIFIED:20181103T155602Z
UID:20786-1541116800-1543881599@ces.b2sg.org
SUMMARY:Postdoctoral Scientist - Immune Oncology
DESCRIPTION:The Beg laboratory focuses on the discovery and development of novel approaches to enhance anti-tumor immunotherapy response\, including identification of promising agents using high-throughput approaches\, cell-based therapies\, and the discovery of biomarkers of response and resistance in ongoing clinical trials. The Beg laboratory is funded by grants from the National Cancer Institute and Dept. of Defense. \nPosition Highlights: \n\nIndividuals in this position will participate in ongoing laboratory and clinical studies to define mechanisms and impact of epigenetic agents on immunotherapy response. Studies will include in-depth mechanistic approaches to define underlying molecular mechanisms\, as well as studies in mouse models of lung cancer and patient clinical samples.\n\nThe Ideal Candidate: \n\nWill have a strong background in immunology and familiarity with basic immunological assays such as flow cytometry.\nPreference will be given to those who have recently graduated with a Ph.D. degree.\n\nResponsibilities: \n\nIndividuals in this position are expected to work under minimal supervision and who are capable of independently designing and executing experimental work.\n\nCredentials and Qualifications: \n\nPh.D. or M.D. in Immunology or related field\n\nSalary and benefits are highly competitive. Review of applications will begin immediately. Please be sure to include your CV with your recent publication(s) and list of 3 references with contact information.
URL:https://ces.b2sg.org/event/moffitt-2nov18/
LOCATION:Moffitt Cancer Center Magnolia Campus\, 12902 USF Magnolia Drive\, Tampa\, FL\, 33612\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/05/Moffitt-1.jpg
END:VEVENT
END:VCALENDAR