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PRODID:-//Cancer Epigenetics Society - ECPv5.3.2.1//NONSGML v1.0//EN
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METHOD:PUBLISH
X-WR-CALNAME:Cancer Epigenetics Society
X-ORIGINAL-URL:https://ces.b2sg.org
X-WR-CALDESC:Events for Cancer Epigenetics Society
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TZID:Europe/Paris
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TZOFFSETFROM:+0100
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DTSTART:20190331T010000
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DTSTART:20191027T010000
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20190128
DTEND;VALUE=DATE:20190302
DTSTAMP:20260904T144726
CREATED:20190128T084256Z
LAST-MODIFIED:20190128T084256Z
UID:21036-1548633600-1551484799@ces.b2sg.org
SUMMARY:Post-Doctoral Research Fellow
DESCRIPTION:The Johnston Laboratory (https://johnstonlaboratory.com/) in the Vaccine and Infectious Disease Division at the Fred Hutchinson Cancer Research Center is recruiting a highly motivated and creative Post-Doctoral Fellow to conduct research relating to synthetic microbiology and microbial genetics / epigenetics. The successful candidate will be involved with delineation of the innate genetic defense systems of bacterial species and the design\, development\, and implementation of methodologies to bypass these systems during genetic engineering. This position will be funded under an NIH Director’s Transformative Research Award (TR01) research grant entitled “The SyngenicDNA and µPOET Platform: Overcoming Innate Barriers to Genetic Engineering in Bacteria.” \n\n*Please include a cover letter with your application\, detailing your interest and suitability for this position. \n\n\n\nResponsibilities\n\n\n\nThe Johnston Laboratory is an interdisciplinary and highly collaborative team of classically trained microbiologists\, synthetic microbiologists\, bioinformaticians and engineers. Using cutting edge technologies and methodologies\, we seek to gain a deeper functional understanding of what bacteria are doing and how they are doing it\, and then to use that information to create novel therapeutics and engineer the next generation of microbe-based technologies for application in human medicine\, synthetic microbiology and bioengineering. \n  \nWet-lab: The ideal post-doctoral candidate must have wet-lab experience in molecular biology and the cultivation/genetic manipulation of non-model bacteria (in addition to laboratory strains of E. coli). Hands-on experience with CRISPR-Cas / Transposon mutagenesis / Recombineering techniques (one or multiple) are essential. Experience with bacterial conjugation is also a plus\, but not required. \n  \nDry-lab: The candidate will work closely with a computational informatician in development/curation of a comprehensive database of genetic defense systems in bacteria\, and accordingly dry-lab experience with Linux-based bioinformatic software / data analysis environments (Python/R) is favorable. Familiarity with handling DNA/RNA sequencing data and related programs will be advantageous. \n\n\n\nQualifications\n\n\n\n\nPh.D. in Microbiology\, Molecular biology\, Bioengineering\, or related field.\nProven expertise with genetic engineering of non-model bacteria\nProven understanding and expertise in synthetic biology techniques (CRISPR-Cas / Transposon mutagenesis / Recombineering / Gene editing tools)\nCandidate must demonstrate outstanding personal initiative and creativity in problem solving\nExperience in scientific programming/scripting for analysis of DNA/RNA sequencing data\nExperience with statistical analysis\nExcellent teamwork\, time management and organizational skills\nAbility to work independently in a dynamic and results-oriented environment\nAbility to present data to a multidisciplinary audience in a clear and concise manner\nAbility to meet deadlines and multitask efficiently is a must
URL:https://ces.b2sg.org/event/28jan19/
LOCATION:Fred Hutchinson Cancer Research Center\, 1100 Fairview Ave. N.\, Seattle\, WA\, 98109-1024\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20190129
DTEND;VALUE=DATE:20190303
DTSTAMP:20260904T144726
CREATED:20190129T073423Z
LAST-MODIFIED:20190129T073423Z
UID:21038-1548720000-1551571199@ces.b2sg.org
SUMMARY:Postdoctoral Fellow
DESCRIPTION:A Postdoctoral Fellow position is available at the Department of Cancer Biology\, Beckman Research Institute at City of Hope. We are looking for a highly motivated postdoctoral fellow interested in studying aging and cancer. Our lab is interested in studying genetic and epigenetic alterations during aging of normal hematopoietic stem cells and in leukemia stem cells that lead to genomic instability\, leukemia development and drug resistance. The lab utilizes bone marrow transplantation and genetic knockout mouse models\, stem cell biology\, and molecular and imaging techniques to study hematopoietic/leukemic stem cells\, and molecular regulation of genomic instability. The outstanding candidate\, particularly with minority background\, may also be eligible for NIH T32 postdoctoral training fellowship in the DNA-damage-response-and-oncogenic-signaling program.\n\nThe ideal candidate is expected to have extensive experience in molecular biology and cell biology. Experience with hematology and rodent models preferred. The candidate should be self-motivated\, with a proven track record of productivity.
URL:https://ces.b2sg.org/event/29jan19/
LOCATION:City of Hope\, 1500 East Duarte Road\, Duarte\, 91010\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20190130
DTEND;VALUE=DATE:20190304
DTSTAMP:20260904T144726
CREATED:20190130T153457Z
LAST-MODIFIED:20190130T153457Z
UID:21042-1548806400-1551657599@ces.b2sg.org
SUMMARY:Postdoctoral Fellow
DESCRIPTION:The Beckman Research Institute of City of Hope is looking for talented Postdoctoral Fellows who will be in the laboratory of Dr. Yilun Liu at the Department of Cancer Genetics and Epigenetics. The focus of the lab relates to the studies of the molecular functions of a group of tumor suppressors known as the human RECQ family helicases. Mutations in different RECQ proteins have been linked to distinct clinical syndromes with various developmental abnormalities\, premature aging phenotypes and cancer predisposition.\n\nWorks from Dr. Liu’s laboratory have established novel models and important mechanistic insights into (a) how Rothmund-Thomson syndrome helicase\, RECQ4\, facilitates efficient nuclear and mitochondrial DNA replication; (b) how mutations in RECQ4 contribute to cancer pathogenesis; (c) how tumor suppressor RECQ5 avoids detrimental DNA damages caused by transcription; and (d) how RECQ5 provides chemo-resistance to Topoisomerase 1-targeting therapy. These findings were published in journals\, including Nature Communications\, Cell Reports\, EMBO Journal and PNAS. Please click here for a full list of publications from Dr. Liu’s laboratory.
URL:https://ces.b2sg.org/event/30jan19/
LOCATION:City of Hope\, 1500 East Duarte Road\, Duarte\, 91010\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20190131
DTEND;VALUE=DATE:20190305
DTSTAMP:20260904T144726
CREATED:20190131T141734Z
LAST-MODIFIED:20190131T141923Z
UID:21047-1548892800-1551743999@ces.b2sg.org
SUMMARY:Postdoctoral Fellow
DESCRIPTION:We are seeking a driven and accomplished postdoctoral fellow to join the Cancer Immunology Discovery (CID) group within the Oncology R&D (WRD) unit of Pfizer. \nThe successful candidate with lead a research project to understand how epigenetic mechanisms control the anti-tumor immune response\, and to translate the findings into better therapies with curative potential for cancer patients. \nThe project builds on promising preliminary data and applies cutting-edge technologies to address what is to date a major scientific question with great clinical implications. Guided by experienced mentors with strong academic track records\, the successful candidate will study fundamental questions in cancer immunology with the goal of publishing in high-impact journals. The postdoc will also interact extensively with leading scientists in small and large molecule drug discovery\, collaborate with computational\, early clinical\, and translational oncology colleagues across Pfizer\, present in internal and external conferences\, and receive mentorship to become a prolific independent scientific investigator. \nROLE RESPONSIBILITIES \nThe successful candidate will work independently\, but with guidance by experienced mentors\, to: \n\nDiscover the novel mechanisms through which epigenetic enzymes regulate T cell activation\, differentiation\, trafficking and exhaustion\, in combination with I-O agents.\nDesign and perform studies to evaluate the anatomical distribution\, persistence and function of antigen-specific T cells in preclinical models of cancer.\nCollaborate with teams in tumor biology\, protein engineering\, computational biology\, clinical development to discover novel biology and as a result identify better treatments for cancer patients.\nPresent at group meetings\, internal and external conferences\, and publish in high impact journals.\nContribute to building a culture that embraces scientific excellence\, integrity\, effectiveness\, humility\, continuous learning and team work.\n\nBASIC QUALIFICATIONS \n\nPh.D. in Immuno-oncology\, Immunology\, Cancer Biology or a comparable biological science\, with a strong track record of scientific publications.\n0-4 years of postdoctoral experience.\nSolid hands-on experience with conventional immunological techniques: immune cell isolation\, multi-color flow cytometry\, in vitro immune cell functional assays and in vivo tumor models.\nExperience in assessing T cell function\, differentiation\, exhaustion and memory development.\nMust have excellent organization and planning skills\, the ability to work in a fast-paced environment independently and as part of a team. Excellent verbal and written communication\, and strong motivation with a dedicated work ethic.\nAble to master new concepts and techniques quickly.\n\nPREFERRED QUALIFICATIONS \n\n2+ years research experience in T cell biology and/or epigenetics.\nStrong understanding of innate and adoptive immune systems.\nPrior experience or a strong interest in developing novel immunotherapies for cancer.\nHands-on experience in qRT-PCR\, ELISA\, Western blotting\, ChIP-seq\, RNA-seq\, ATAC-seq and CyTOF is desirable.\nHands-on experience in CRISPR\, RNAi\, lentiviral transduction and exogenous gene expression is a plus.\nHands-on experience in syngeneic and spontaneous tumor models\, adoptive cell transfer is desirable.
URL:https://ces.b2sg.org/event/pfi31jan19/
LOCATION:Pfizer – La Jolla\, CA\, 10350 N Torrey Pines Rd\, La Jolla\, CA\, 92037\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20190131
DTEND;VALUE=DATE:20190304
DTSTAMP:20260904T144726
CREATED:20190131T151801Z
LAST-MODIFIED:20190131T151801Z
UID:21050-1548892800-1551657599@ces.b2sg.org
SUMMARY:Postdoc Fellow
DESCRIPTION:Post Doctoral Fellow positions are available in the laboratory of Dr. Matthew Weitzman\, at the Children’s Hospital of Philadelphia (CHOP) and the University of Pennsylvania (Penn). Our lab is part of the rich scientific environment on the CHOP/Penn campus that includes multiple areas of virology\, immunology\, cancer\, and epigenetics. We are located in the new Colket Translational Research Building as part of the Division of Cancer Pathobiology\, in the Department of Pathology & Laboratory Medicine. The lab is also part of the Center for Childhood Cancer Research (CCCR)\, the Center for Cellular & Molecular Therapeutics (CCMT)\, the Penn Institute for Immunology (IFI)\, the Penn Epigenetics program\, and Penn Center for AIDS Research (CFAR). \nThe lab’s research focuses on virus-host interactions and the use of viruses as model systems to study DNA repair\, signaling\, cell biology\, replication\, innate host defenses and gene delivery. We are interested in virus replication and the resulting cellular responses. We study the intersection of virus and host pathways during infection and how they reveal insights into fundamental cellular mechanisms. We are particularly interested in recognition and processing of viral genomes by DNA repair and APOBEC pathways. We are using virus systems to study signaling\, ubiquitination and degradation\, and transcriptional silencing. Viral model systems include adeno-associated virus (AAV)\, adenovirus (Ad) and herpes simplex virus (HSV). \n\nJob Responsibilities \n\nConduct independent scholarly research and develop new methods and protocols\nParticipate in project planning\, recording and evaluation of data\nAcquire technical\, lab management and grant writing skills\nParticipate in seminars\, lectures\, poster sessions and presentation at national meetings\nSupervise junior lab members\nAssist with other research projects\n\n\nRequired Education and Experience \n\nA terminal degree PhD\, MD\, DVM\, etc.\nAccording to the CMS (Centers for Medicaid and Medicare Services) a copy of diploma or transcript is required as proof of academic achievement for all non-laboratory personnel performing non-waived POC testing
URL:https://ces.b2sg.org/event/31jan19/
LOCATION:WA
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20190201
DTEND;VALUE=DATE:20190305
DTSTAMP:20260904T144726
CREATED:20190201T075734Z
LAST-MODIFIED:20190201T083910Z
UID:21052-1548979200-1551743999@ces.b2sg.org
SUMMARY:College Research Intern
DESCRIPTION:Cold Spring Harbor Laboratory is currently seeking a college-level intern to work in the Computational Genomics laboratory of Dr. Alexander Dobin. The intern will join a team of biological data scientists working on novel statistical methods and computational algorithms for multi-omics processing and integration\, and leverage Big Genomic Data to elucidate various problems in precision health\, such as genetic and epigenetic mechanisms of cancer development and progression\, and clinical impact of functional variants. \nPosition Requirements \nEDUCATION: College student enrolled in an undergraduate degree in biology\, computer science molecular biology\, genetics or related disciplines. Junior year is preferred. \nEXPERIENCE: Experience in scientific data analysis (C/C++\, Python\, Matlab\, R)\, familiarity with genomics and the next-generation sequencing technologies. Strong interest in science and research. \nOTHER: Ability to work 20 – 35 hours/week in the summer. Must have reliable transportation . \nIf interested\, please apply for this position via the CSHL website at: http://cshl.peopleadmin.com/postings/14861 \nPosition Number: 02304-R
URL:https://ces.b2sg.org/event/csh-1feb19/
LOCATION:Cold Spring Harbor Laboratory\, 1 Bungtown Road\, Cold Spring Harbor\, NY\, 11724-2213\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20190201
DTEND;VALUE=DATE:20190305
DTSTAMP:20260904T144726
CREATED:20190201T085738Z
LAST-MODIFIED:20190201T085738Z
UID:21055-1548979200-1551743999@ces.b2sg.org
SUMMARY:Postdoctoral Associate
DESCRIPTION:The Terskikh laboratory has a Postdoctoral Associate opening. This position focuses on the novel approach to study epigenetics at a single cell level. The Postdoc Associate will explore the capability of Microscopic Imaging of Epigenetic Landscape (MIEL) and fluorescence-based reporters enabling live imaging of epigenetic modifications at a single cell level. MIEL combines fluorescence detection of epigenetic marks with automated cell imaging and machine learning to profile and quantify the “epigenetic signatures” of individual cells. They will investigate the epigenetic heterogeneity at the single cell level and the asymmetry during stem cell division in normal neurogenesis and in brain tumors. One of the long-standing question of this project is to determine whether the outcome of stem cell division is stochastic or deterministic and whether such outcome could be predicted based on the epigenetic signature of the mother cell. \nTO APPLY: Interested candidates should apply online to the SBP career site by submitting one PDF document with a cover letter\, CV\, references and list of any publications or accomplishments. \n\nDuties and Responsibilities\n\n\n\nIndependently design and perform experiments and procedures with high degree of complexity\, demonstrating increasing expertise with a wide range of techniques\nDemonstrate flexibility in adapting methods and skills according to evolving project priorities\nProvide independent experimental design and planning\nBe able to analyze and interpret data from different sources and draw relevant conclusions\nDemonstrate knowledge in relevant specialized disciplines\nBe able to present results at internal and external meetings\nAccurately document experiments\nContribute to writing of reports and manuscripts with increasing responsibility over time\nWork collaboratively across lab functions and train other junior lab staff as needed\n\n\n\n\n\nRequired Skills \nRequired Experience \n\n\n\nPh.D. degree in any discipline of Biological Sciences is required\nThe qualified candidate must have proven experience in one or more of the following areas: Tissue culture\, cell and molecular biology\, fluorescent microscopy\, and computational biology\nExperience with transgenic mice model is highly desirable\n\n\n\n\nOther Knowledge\, Skills and/or Abilities\n\nThe ability to work independently and to handle multiple projects and deadlines\nDemonstrated ability to work in an interactive and collaborative team\nExcellent presentation\, verbal\, and written communication skills\nPossess strong attention to detail\, analytical\, time management\, organizational\, and interpersonal skills\nEmbody the Institute’s core values of Commitment\, Collaboration\, Communication\, Community and Compassion
URL:https://ces.b2sg.org/event/sbp-1feb19/
LOCATION:Sanford Burnham Prebys Medical Discovery Institute\, 10901 N Torrey Pines Rd\, La Jolla\, CA\, 92037\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20190201
DTEND;VALUE=DATE:20190305
DTSTAMP:20260904T144726
CREATED:20190201T091610Z
LAST-MODIFIED:20190201T091610Z
UID:21057-1548979200-1551743999@ces.b2sg.org
SUMMARY:Senior Bioinformatician(s)
DESCRIPTION:Do you enjoy working with computational scientists\, biologists and clinicians in a dynamic\, interdisciplinary and collaborative environment? Our lab (http://www.tsirigos.com/) at the NYU School of Medicine is seeking highly motivated\, enthusiastic and creative individuals to investigate the role of genetics\, epigenetics and chromatin organization in cancer and/or apply machine learning to develop novel cancer diagnostics. The successful candidate will have the opportunity to work on various types of large genomics and/or imaging datasets and will interact closely with our experimental collaborators and clinicians. The successful candidate will also interact with a vibrant group of bioinformaticians in the Applied Bioinformatics Laboratories (http://nyulmc.org/abl). ABL provides computational support and expertise to promote innovative cutting-edge research conducted by principal investigators at the NYU Langone Medical Center. This is a great opportunity to quickly acquire new skills\, develop and publish new tools and methods\, analyze challenging datasets and be a co-author in multiple studies. \nRequired skills \n\nPh.D. or M.Sc. in Bioinformatics\, System Biology\, Computer Science or related field\nKnowledge of biology and understanding of key and complex biological concepts (genes\, pathways\, cancer and/or stem cells)\nAbility to work independently while collaborating and assisting the team in its common research goals\nAttention to detail and ability to work on multiple projects is necessary\nExperience in Unix/Linux systems including HPC environments\nScripting languages: Python (preferred) or Perl\nStatistical packages: R (preferred) or Matlab.\n3+ years of experience with sequencing data (e.g. DNA-seq\, RNA-seq\, ATAC-seq or ChIP-seq)\n3+ years of experience creating customized sequencing analysis pipelines\nExcellent communication skills with proficiency in written and oral English\n\n\nExperience: \n\nMachine Learning: 1 year (Preferred)\nPython: 3 years (Required)\nR: 3 years (Required)
URL:https://ces.b2sg.org/event/nyu-1feb19/
LOCATION:NYU School of Medicine\, 550 1st Avenue\, New York\, NY\, 10016\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20190211
DTEND;VALUE=DATE:20190313
DTSTAMP:20260904T144726
CREATED:20190211T095321Z
LAST-MODIFIED:20190211T095321Z
UID:21059-1549843200-1552435199@ces.b2sg.org
SUMMARY:Postdoctoral Fellow
DESCRIPTION:Funded by the City of Hope\, this program provides exceptionally motivated postdoctoral fellows with scientific knowledge\, research training and professional skills in the rapidly growing and interconnected fields of cancer metabolism. The goal of the program is to provide innovative curriculum and mentored research that prepares an elite group of highly motivated fellows to become successful\, independent researchers in cancer biology. Fellows can choose a mentor from 31 faculty members\, all of whom are performing cancer-focused\, funded\, high-impact research in cancer metabolism\, and have a history of mentoring postdoctoral fellows. Required coursework includes a class in Cancer Metabolism. In addition\, trainees will participate in journal clubs\, data clubs\, professional development seminars\, monthly luncheons with mentors\, national and international scientific conferences\, and a yearly Cancer Metabolism Day.\n\nFellowships are for up to three years with an institute-supplemented stipend ($58\,000 per year plus a full benefit package) and $5\,000 for research supplies.\n\nU.S. citizenship or U.S. permanent resident status is required. Individuals from underrepresented minority groups are strongly encouraged to apply.\n  \nBasic education\, experience and skills required for consideration: \n\n\nApplicants must have a completed doctoral degree before starting the fellowship program (all Ph.D. coursework must be completed\, final orals must be passed and the dissertation signed). Applicants who are currently postdoctoral fellows must have less than one year of postdoctoral experience. U.S. citizenship or U.S. permanent resident status is required. Individuals from underrepresented minority groups are strongly encouraged to apply.\n\n\nApplications are accepted on a rolling basis. Selection criteria include: academic training\, research interest in cancer metabolism\, strength of commitment to an academic research career\, potential to contribute significantly to the field.
URL:https://ces.b2sg.org/event/hope-11feb19/
LOCATION:City of Hope\, 1500 East Duarte Road\, Duarte\, 91010\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20190213
DTEND;VALUE=DATE:20190317
DTSTAMP:20260904T144726
CREATED:20190213T170507Z
LAST-MODIFIED:20190213T170507Z
UID:21061-1550016000-1552780799@ces.b2sg.org
SUMMARY:Scientific Grant Writer
DESCRIPTION:The Van Andel Research Institute (VARI) is an independent and world-class biomedical research institute dedicated to determining the fundamental molecular origins of disease and translating those findings into effective therapies. VARI is home to more than 300 scientists and staff that work in on-site laboratories and collaborative partnerships that span the globe. VARI’s research pillars are built upon epigenetics\, cancer and neuro-degeneration research\, and in late 2018 a brand new inter-disciplinary program focusing on nutrition and metabolism was created. \n\nThe Pospisilik lab\, a founding member of this new initiative and Center Lead for the Institute’s Center of Epigenetics\, aims to understand the epigenetic basis of complex disease with a focus on inflammation\, cancer\, diabetes and obesity\, and to leverage their findings to push forward novel therapeutic and preventative medicines. \n\nTo ensure an efficient and dynamic pace to the core science\, the establishment and the expansion of the new metabolism initiative\, the Pospisilik Lab is actively seeking a talented Scientific Grant Writer to support Dr. Pospisilik in preparing grant applications for extramural funding opportunities. \n\nIn particular\, you will: \n\n\n\nSearch for and identify potential funding sources to support the lab’s research.\nWriting/editing high quality grant proposals for submission to a variety of funding institutions.\nContribute to the scientific knowledge and analytical skills in the preparation of grant proposals\, manuscripts\, and protocols.\nProvide full life cycle editing and writing support for grant submissions\, including managing timelines and project milestones\, collecting figures\, illustrations\, and information from various sources\, editing documents and coordinating with multiple stakeholders involved in the submission.\nSteer research projects and acquisition of preliminary data for individual and group efforts.\nWork closely with the Sponsored Research Office to compile and submit grant applications in a timely manner.\n\n\n\n\nWhat traits and characteristics are expected of you? \n\n\n\nHighly motivated\, ambitious\, possesses strong planning and organizational skills\, and brings innovation/creative thinking about science.\nA strong commitment to building and maintaining a positive work environment.\nStrong skills and enjoyment in scientific writing.\n\n\n\n\nQUALIFICATIONS \nRealistically you would possess a Ph.D.\, have expertise in Molecular Epigenetics and/or Metabolism\, have completed postdoctoral training experience\, and possesses a strong record of successful grant writing proposals. We will consider a Master’s degree with broad and in depth experience in technical writing. Regardless of your education\, you must be a leader\, and above all\, a team player. \nIn addition you should also possess: \n\n\n\nIdeally 3 -5 years of experience in grant writing proposals and peer reviewed publications. This includes strong writing\, editing\, and preparing of high quality written scientific documents.\nExperience in submitting grant proposals to National Institutes of Health\, Department of Defense\, and other federal\, non-profit\, and/or private funding agencies and organizations.\n\n\n\n\nHOW TO APPLY \nIf you possess these attributes and enjoy working with motivated and driven people\, we would welcome speaking with you and encourage you to apply today by submitting a cover letter describing your research interests\, experience\, and how you might contribute to Pospisilik Lab Research. \n\nAn up-to-date Curriculum Vitae.\n\n\n\n\nA list of 2-3 references along with their contact details.\n\n\n\n\nPlease contact Eric Miller (eric.miller@vai.org) for further information or questions\, or if you have any difficulty with the application process.
URL:https://ces.b2sg.org/event/13feb19/
LOCATION:Van Andel Research Insitute\, Grand Rapis\, MI\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20190214
DTEND;VALUE=DATE:20190318
DTSTAMP:20260904T144726
CREATED:20190214T112506Z
LAST-MODIFIED:20190214T112506Z
UID:21063-1550102400-1552867199@ces.b2sg.org
SUMMARY:Principal Research Associate/Scientist\, Lead Discovery
DESCRIPTION:The successful candidate will serve as an integral member of a multidisciplinary drug discovery project team developing novel inhibitors targeting epigenetic enzymes implicated in cancer. As a member of the Lead Discovery Team\, the qualified candidate will be required to employ a variety of in vitro biochemical techniques to develop enzyme assays and explore the mechanism of action for small-molecule inhibitors. \nResponsibilities \n\nAssess activity and substrate specificity for enzyme preparations\nDesign and develop enzymatic assays for inhibitor identification\nValidate screening hits through mechanism of action studies on small-molecule inhibitors\nMaintain a panel of routine screening assays for specific project teams\nMaintain and track an inventory of biochemical reagents\nManage good working relationships with CRO vendors providing high quality biochemical data\nGenerate SOP documents\nManage uploading of data to an internal database\n\nRequirements \n\nMS in Biochemistry or a related field plus minimum 3-5 years of relevant industry experience\, or PhD in Biochemistry or a related field\n\n\nAbility to plan and troubleshoot experiments\nExceptional time management skills\nUnparalleled analytical\, organizational and communication skills\nAbility to work well under pressure and drive projects that affect critical timelines
URL:https://ces.b2sg.org/event/14feb19/
LOCATION:Epizyme\, 400 Technology Square\, Cambridge\, MA\, 02139\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20190216
DTEND;VALUE=DATE:20190320
DTSTAMP:20260904T144726
CREATED:20190216T201737Z
LAST-MODIFIED:20190216T201737Z
UID:21065-1550275200-1553039999@ces.b2sg.org
SUMMARY:Research Fellow
DESCRIPTION:Postdoctoral Fellow\, Chemist/chemical biologist \nThere is an immediate opening for a Postdoctoral Fellow in the Qi group at the Dana-Farber Cancer Institute to look for exceptional Postdoctoral Fellows in Chemistry and Chemical Biology field. The Qi lab studies gene regulatory pathways using the emerging discipline of chemical biology. Successful candidates will work with an interdisciplinary team of scientists including medicinal chemists\, biochemists\, computational biologists\, and cancer biologists to develop novel inhibitors of chromatin modifying enzymes\, such as methyltransferases\, demethylases as well as other epigenetic targets and transcription factors. The successful candidate will perform research that establishes fundamental insights to cancer biology using novel small molecule inhibitors to gain mechanistic understanding in cancer therapy. We expect that novel therapeutics for human clinical investigation will emerge directly from these efforts through academic/industry collaborations. \nThe postdoctoral fellow will be affiliated with the Department of Cancer Biology at Dana-Farber Cancer Institute\, the Department of Medicine at Harvard Medical School and the Broad Institute. \n\n\n\nResponsibilities\n\n\n\nWe are seeking an enthusiastic\, self-motivated\, and experienced bench-level synthetic chemist who is willing to learn multi-discipline approach for cancer research to join our team. The major focus of this position will include developing and executing design and synthesis small molecule inhibitors while investigating novel biological mechanisms of action of inhibitors in cancer with team. \n\nPerforming synthesis and development of small molecule inhibitors under structure guidance.\nExperience in computational modeling is a plus.\nPerforming laboratory experiments and conducting data analysis.\nCollaborating with team members and collaborators to understand the target inhibition in different cancers.\nDesigning experiments and executing protocols.\nMaintaining accurate records\, writing reports\, and preparing/giving presentations.\nChemical biology/Biology background is preferred but not required.\n\n\n\n\nQualifications\n\n\n\n\nPhD in chemistry\, medicinal chemistry\, chemical biology or equivalent\nA strong understanding in biochemistry\, chromatin biology\, cancer biology is preferred\, but not required.\nExcellent oral and written communication skills.\nThe ability to perform both self-directed and guided research is required.\nMust demonstrate outstanding ability to work effectively as part of an interdisciplinary team of scientists.
URL:https://ces.b2sg.org/event/16feb19/
LOCATION:Dana-Farber Cancer Institute\, 450 Brookline Avenue\, Boston\, MA\, 02215\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20190217
DTEND;VALUE=DATE:20190321
DTSTAMP:20260904T144726
CREATED:20190217T210917Z
LAST-MODIFIED:20190217T210917Z
UID:21067-1550361600-1553126399@ces.b2sg.org
SUMMARY:Postdoctoral Associate
DESCRIPTION:A Postdoctoral Associate position is available in the lab of Dr. Tao Wu in the Department of Molecular & Human Genetics at Baylor College of Medicine (https://www.bcm.edu/research/labs/tao-wu). The Wu lab focuses on the epigenetic mechanisms of cancer therapeutic resistance; in particular\, the functional mechanisms of novel DNA methylation (6mA). We seek to decipher the epigenetic driver mechanisms underlying cancer treatment resistance\, to define new biomarkers\, and to develop new approaches to overcome the therapeutic resistance of cancer. We apply multiple wet lab techniques\, as well as dry lab genomic profiling and bioinformatics approaches in cancer models. \nWe are seeking a Postdoctoral Associate whose research will focus on bioinformatics.  This position will require developing analytical approaches to solve computational scripts and analytical code\, genomic data analysis of sequencing data sets\, and generating statistical figures.  Experience in genomic profiling data analysis\, cancer epigenetics\, and/or bioinformatics analysis preferred.  Please apply at https://chk.tbe.taleo.net/chk01/ats/careers/requisition.jsp?org=BCM&cws=42&rid=18295 \nIdeal candidates should be able to creatively conceive the study\, critically design experiments and insightfully analyze genomic data. Applicants should be self-motivated\, open-minded\, detail-oriented and collaborative. Expertise in one (or more) of the following research areas is required: molecular and cell biology\, genetics\, genomics\, bioinformatics\, and systems biology studies. \nAll applicants are encouraged to apply at www.bcm.edu/careers.  Work visa sponsorship available for qualified candidates. \nApplication process: \nFor more information and to apply please visit www.bcm.edu/careers \nIn addition to submitting an application\, applicants should send a cover letter describing past research experience and potential research projects\, a curriculum vitae\, and the contact information of three references to Dr. Tao Wu (Tao.Wu@bcm.edu) with the subject line “2019__Postdoc Application _ (Your Name)”.
URL:https://ces.b2sg.org/event/b17feb19/
LOCATION:Baylor College of Medicine\, 1 Baylor Plaza\, Houston\, TX\, 77030\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20190219
DTEND;VALUE=DATE:20190323
DTSTAMP:20260904T144726
CREATED:20190219T121239Z
LAST-MODIFIED:20190219T121239Z
UID:21075-1550534400-1553299199@ces.b2sg.org
SUMMARY:Postdoctoral Training- Molecular Epidemiology
DESCRIPTION:The Cancer Epidemiology Program of the H. Lee Moffitt Cancer Center & Research Institute\, Inc. invites applications to its T32 Post-Doctoral Training Program in Molecular Epidemiology of Cancer. This NCI-supported interdisciplinary training program is designed to prepare fellows for careers as independent investigators engaged in cancer epidemiological research that incorporates biomarkers identified at the molecular\, biochemical\, or -omic level. The two year program combines a specialized curriculum (formal didactic training and one-on-one interactions with mentors) with research experience (participation in funded studies under the guidance of an experienced investigator). \nMentoring will be provided by teams of experienced faculty from a variety of epidemiology-related disciplines\, including cancer epidemiology\, statistical genetics\, cancer genetics\, bioinformatics and clinical specialties spanning diverse areas of research interests and cancer sites. Selected research interests of faculty in Cancer Epidemiology include: \n\nDevelopment of quantitative imaging models to improve risk prediction and reduce over-diagnosis of lung cancer\nEnvironmental and genetic risk factors of melanoma and familial melanoma\nEpidemiologic\, molecular biomarker\, and radiologic approaches to impact pancreatic cancer and its precursor lesions\nGenetic\, viral\, and nutritional risk factors of primary brain tumor glioma\nGenetic and epigenetic biomarkers associated with risk and progression of prostate cancer\nIntegrative molecular epidemiology approaches to dissect the function of cancer susceptibility loci identified by GWAS\nInterplay of cutaneous malignancies with cutaneous viral infections\, UV radiation exposure and immune function\nLife course approaches to evaluate epidemiologic exposures affecting ovarian cancer development and progression\nHPV natural history and clinical trials for the prevention of HPV-related cancers\n\nApplicants must have a terminal degree in epidemiology\, nursing\, public health\, medicine or related discipline. We expect that most candidates will have some previous training in epidemiology and/or biostatistics. Stipends and benefits are highly competitive. Review of applications will begin immediately and continue until our open positions for the 2018-19 academic year is filled. Applicants must be U.S. citizens or legal permanent residents. Individuals on temporary visas are not eligible. \nVisit our website www.moffitt.org/CancerEpidemio… for information on \napplying and application materials. Email a completed application packet to \nMeredith.Brenner@Moffitt.org.
URL:https://ces.b2sg.org/event/19feb19/
LOCATION:Moffitt Cancer Center Magnolia Campus\, 12902 USF Magnolia Drive\, Tampa\, FL\, 33612\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20190220
DTEND;VALUE=DATE:20190324
DTSTAMP:20260904T144726
CREATED:20190220T190151Z
LAST-MODIFIED:20190220T190151Z
UID:21077-1550620800-1553385599@ces.b2sg.org
SUMMARY:Postdoctoral Research Associate
DESCRIPTION:A postdoctoral position is available to teach gross anatomy under the supervision of Dr. Rebecca Fisher in the Department of Basic Medical Sciences at the University of Arizona College of Medicine – Phoenix. Current faculty research areas in the department include: phylogenetics and mammalian paleontology; human and primate skeletal anatomy; paleoanthropology; bioarchaeology and paleopathology; and vertebrate and invertebrate functional anatomy. \nThe Department of Basic Medical Sciences is a multidisciplinary unit composed of faculty with research interests in cardiac and vascular biology; developmental\, cell and molecular biology; evolution of vertebrate morphology; gene environment interactions and epigenetics; host-microbe interactions and immunology; medical education; platform development\, medical devices and procedures; and signaling and steroid biology. In addition\, the Center for Applied NanoBioscience and Medicine and affiliate institutions such as the Translational Genomics Research Institute\, Phoenix Children’s Hospital\, St. Joseph’s Hospital/Barrow Neurological Institute and the Arizona Alzheimer’s Consortium offer abundant opportunities for collaborative research efforts. \nThe University of Arizona College of Medicine – Phoenix anchors the 28-acre Phoenix Biomedical Campus in the heart of the Valley of the Sun. The College inspires and trains individuals to become exemplary physicians\, scientists and leaders who are life-long learners and inquisitive scholars. We embrace professionalism\, innovation and collaboration to optimize health and health care for all. The Phoenix Biomedical Campus embodies the University’s priorities of engagement\, partnership\, innovation\, and synergy in its world-class academic and research initiatives\, with clinical facilities throughout Greater Phoenix. The campus also houses the UA Colleges of Public Health\, Pharmacy\, and Nursing\, as well as Northern Arizona University’s College of Health and Human Services\, the Translational Genomics Research Institute (TGen) and the International Genomics Consortium. The University of Arizona Cancer Center in association with Dignity Health recently opened a new clinical facility and a new research building is under construction. \nOutstanding UA benefits include health\, dental\, vision\, and life insurance; paid vacation\, sick leave\, and holidays; UA/ASU/NAU tuition reduction for the employee and qualified family members; access to UA recreation and cultural activities; and more! \nThe University of Arizona has been listed by Forbes as one of America’s Best Employers in the United States and WorldatWork and the Arizona Department of Health Services have recognized us for our innovative work-life programs. For more information about working at the University of Arizona and relocation services\, please click here. \nDuties & Responsibilities \n\nTeach gross anatomy to medical\, physician assistant\, physical therapy\, and graduate students\, including lab instruction\, selected lectures\, office hours\, and review sessions.\n\n\nAssist the anatomy faculty in writing and revising exam questions and setting up and proctoring exams.\n\n\nTeach in the summer remediation course for medical students and community outreach programs for high school students.\n\n\nConduct research in the anatomical sciences or medical education\, submit research for publication in peer reviewed journals\, and present findings at departmental seminars and professional meetings.\n\nKnowledge\, Skills\, & Abilities Minimum Qualifications \n\nPhD degree.\n\n\nPrior human anatomy teaching experience in a dissection-based course.\n\nPreferred Qualifications \n\nResearch interests in phylogenetics and mammalian paleontology; human and primate skeletal anatomy; paleoanthropology; bioarchaeology and paleopathology; or vertebrate/invertebrate functional anatomy.
URL:https://ces.b2sg.org/event/20feb19/
LOCATION:University of Arizona\, Tuscon\, AZ\, 85721\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20190221
DTEND;VALUE=DATE:20190325
DTSTAMP:20260904T144726
CREATED:20190221T180326Z
LAST-MODIFIED:20190221T180326Z
UID:21079-1550707200-1553471999@ces.b2sg.org
SUMMARY:Sr. Scientist - Sequencing Research
DESCRIPTION:We are seeking a talented highly motivated research scientist to join our new Sequencing Research capability in San Diego. The successful candidate will work on novel NGS profiling approaches to elucidate disease state from patient biospecimens\, PDX and organoid models\, and multi-cellular pre-clinical disease models. Work performed will contribute to therapeutic discovery and early translational research programs in oncology\, autoimmune and neurological indications. \nThe role will involve extensive partnership with scientist colleagues from across Celgene Research & Early Development (R/ED) to drive new experimental\, data capture and sample rescue strategies\, and will include inter-disciplinary collaboration with analytical research colleagues to maximize the depth and robustness of insights derived from transcriptional\, mutational and epigenetic profiling datasets. Areas of technical research focus include the successful profiling of rare\, damaged or low-yield samples\, and collaborative pursuit and assessment of diagnostic assay hypotheses. \nKey stakeholders include researchers in our thematic centers of excellence (TCoEs)\, our Translational Development and Diagnostics (TDD) function\, and colleagues in the Research Informatics and Knowledge Utilization (RIKU) department\, engaged in work towards key objectives for Celgene Research and Early Development (R/ED). \nThis position suits an individual with demonstrated scientific talent and future leadership potential\, with excellent communication and collaboration skills. Keen interest in inter-disciplinary application of high-throughput molecular profiling methods to life sciences data is imperative.\nApplications are encouraged from those looking to impact delivery of truly innovative and life-changing therapies for complex diseases of unmet medical need. \nResponsibilities will include\, but are not limited to\, the following: \n\nCollaborative design and execution of NGS profiling experiments to elucidate disease state and therapeutic response\, with focus on successful profiling of rare\, damaged or low-yield samples\, and collaborative pursuit and assessment of diagnostic assay hypotheses.\nResearch at the leading edge of NGS sample preparation and profiling technologies\, including implementation of novel protocols drawn from the literature\, Celgene academic collaborators\, and/or in-house efforts\, aligned to Celgene scientific research objectives.\nAdvise on sample extraction\, library preparation and QC\, guide collection of supporting metadata\, liaise with computational research colleagues during analytical research\, and translational scientists involved in diagnostics research.\nDesign and perform pilot experiments to test new protocols\, and assess new profiling platforms and external vendor capabilities.\nContribute to the operation of internal next-generation sequencing resources and development of supporting infrastructures\, including documentation of protocols developed and supervision of technical support staff as required.\nPresent strategies\, approaches\, results and conclusions to Celgene colleagues and external audiences to a publishable standard.\nContribute to enable strategic collaborations with academic and commercial collaborators to benefit therapeutic programs.\n\n\nSkills/Knowledge Required: \n\nPh.D. in biology\, biochemistry or related discipline at a recognized higher-education establishment.\nAt least 6 years of inter-disciplinary research experience with focus on cell or molecular profiling for elucidation of human disease in university\, hospital or biotechnology research scenarios.\nExpertise in performing state of the art NGS studies with demonstrable record of innovative protocol development and peer-reviewed publication in relevant areas.\nExpertise in the generation of robust molecular profiling datasets from low-yield\, damaged or contaminated human samples for translational research objectives. \nExperience in use of NGS profiling methods to answer complex research questions in cancer biology\, autoimmune disease\, epigenetics and/or immune biology.\nHands-on experience of sample and library preparation\, operation and maintenance of high- and low-throughput NGS apparatus (Illumina preferable).\nIn-depth knowledge of contemporary NGS technologies and experimental design considerations\, and familiarity with downstream bioinformatics approaches applied to process\, analyze\, visualize and interpret NGS datasets.\nAwareness of contemporary LIMS schema\, open-source bioinformatics tools and database structures.\nExperience in performing functional assays to validate experimental findings.\nExcellent time management and organizational skills\, proven problem-solving skills\, collaborative nature and adaptability across disciplines\nExcellent verbal and written communication skills. Fluent verbal and written English language skills prerequisite.
URL:https://ces.b2sg.org/event/cel-21feb19/
LOCATION:Celgene San Diego\, 10300 Campus Point Dr\, San Diego\, CA\, 92121\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20190225
DTEND;VALUE=DATE:20190329
DTSTAMP:20260904T144726
CREATED:20190225T153243Z
LAST-MODIFIED:20190225T153448Z
UID:21081-1551052800-1553817599@ces.b2sg.org
SUMMARY:Faculty Position
DESCRIPTION:The Department of Urology and the Robert H. Lurie Comprehensive Cancer Center at Northwestern University Feinberg School of Medicine are leading the search for a full-time tenure track Investigator at the rank Assistant Professor in the area of prostate cancer biology and cancer epigenetics. \nQualified candidates will have a PhD or MD or dual degree and an outstanding record of research in prostate cancer biology and cancer genetics. The successful applicant will have experience in the field of cancer biology\, including cancer genetics and proteomics\, cancer cell biology\, tumor microenvironment\, cancer stem cells\, metastasis\, tumor immunology\, chemical biology\, cancer metabolism\, oncogenic signal transduction pathways\, genome integrity\, and cancer epigenetics.  We are seeking an individual with an established program in prostate cancer who is drawn to the broad opportunities at Northwestern with its collaborative clinical programs at Northwestern Memorial Hospital. The Center for Genetic Medicine houses the NUgene biobank and the Robert H. Lurie Comprehensive Cancer Center offers a robust research infrastructure for translation. \nThe start date is negotiable and the position will remain open until filled. When applying\, please upload this completed list of references form to suggest the names of individuals who could write letters of reference on your behalf. \nPlease read ALL instructions and make preparations before proceeding to the application page: \n\nApplications will only be accepted via online submission (see link below).\nPlease prepare all documents in advance as Adobe PDF files\, and please be sure all information is entered correctly and accurately (especially names and email addresses)\, as there will be no opportunity for online revision after your application has been submitted.\nAll required fields in the application form are marked with an asterisk and must be filled before clicking the “Submit” button.\nBe aware that incomplete applications cannot be saved.
URL:https://ces.b2sg.org/event/nwu-25feb19/
LOCATION:Northwestern University\, 633 Clark St\, Evanston\, IL\, 60208\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20190226
DTEND;VALUE=DATE:20190331
DTSTAMP:20260904T144726
CREATED:20190226T184944Z
LAST-MODIFIED:20190226T184944Z
UID:21084-1551139200-1553990399@ces.b2sg.org
SUMMARY:Postdoctoral Scientist
DESCRIPTION:This position is primarily a temporary/training position in which the incumbent plays a substantive role in planning and conducting research by designing and conducting experiments in a controlled laboratory setting. In collaboration with the Principal Investigator\, this role will participate in the planning of independent research\, will analyze and interpret data\, will publish results\, will represent the university at conferences and meetings\, and may develop new theories and methodologies. This position may also help the Principal Investigator to lead and direct the work of lower level research staff. This role performs work under the supervision of experienced researchers. \nAdditionally\, the Postdoctoral Scientist utilizes several techniques including DNAmethylation and histone marks\, RNA-IP\, ChIP assay\, Molecular cloning\, mass spectrometry\, site directed mutagenesis\, in-vitro transcription. \nOther duties:\n-Interprets assay results \n-Summarizes findings\n-Assist with manuscript preparation\n-Performs other work related duties as assigned. The omission of specific duties does not preclude the supervisor from assigning duties that are logically related to the position \n\nPreferred Qualifications: \nPh.D in biochemistry\, molecular biology\, immunology or related field preferred. \nStrong experience in Immunology\, Epigenetics\, Cancer biology and animal handling\, in addition to some of the following laboratory techniques: tissue culture\, mouse models\, immunological techniques\, molecular biology\, flow cytometry and cellular biology etc. desired.
URL:https://ces.b2sg.org/event/26feb19/
LOCATION:George Washington University\, 2121 I St NW\, Washington\, DC\, 20052\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20190227
DTEND;VALUE=DATE:20190401
DTSTAMP:20260904T144726
CREATED:20190227T093319Z
LAST-MODIFIED:20190227T093319Z
UID:21086-1551225600-1554076799@ces.b2sg.org
SUMMARY:Staff Scientist - DNA damage & repair
DESCRIPTION:One (1) staff scientist position is available in October 2019 in the Laboratory of Genome Integrity (Center for Cancer Research\, National Cancer Institute\, National Institutes of Health) to use computational methods in the study of mechanisms involved in DNA double-strand break repair and the roles of repair and replication proteins in a variety of cancers that include leukemias and breast cancers\, using mouse models. The ideal candidate will play a leading role in providing computational and biological insight by analyzing large data sets derived from genomics\, epigenetics and proteomics experiments. The position will emphasize efforts to understand gene regulation\, chromatin\, regulatory and coding variation and its relation to cancer. The position will support all laboratory investigators who use applications involving high-throughput DNA sequencing methods for a variety of assays\, including RNA-seq\, exon sequencing\, ATAC-seq\, DNase-seq\, ChIP-seq and newer and cutting-edge methodologies such as END-seq that have recently been developed.  Salary is commensurate with experience. \n\n\n\n\nNumber of Positions: \n\n1\n\n\n\nC.V. Required: \n\nYes\n\n\n\nNumber of References Required: \n\n3\n\n\n\nExperience Required: \n\n\nQualified candidates should have: \n\nA Ph.D. in computational biology\, bioinformatics\, mathematics\, or related field with no more than five (5) years of postdoc experience;\nResearch fellows in the NCI are encouraged to apply;\nAbility to program in Python/Perl and R/Matlab in Unix environment is required;\nKnowledge of SQL will be considered a plus;\nDemonstrated applied bioinformatics/computational proficiency as evidenced by relevant publications in peer-reviewed journals;\nStrong computational as well as a strong biological background;\nAn interdisciplinary background in bioinformatics & computational biology;\nAdvanced expertise in the analysis and interpretation of sequencing data generated in-house and its integration with other “omics” data sources such as ENCODE and TCGA;\nLaboratory bench experience\, while not essential\, will be considered an advantage.\n\n\n\n\n\nHow To Apply: \n\n\nCandidates should send CV and three (3) letters of reference via email directly to sam.john@nih.gov \n\n\n\n\nContact Name: Sam John\n\n\nContact E-mail: sam.john@nih.gov\n\n\nContact Phone: 240-760-7601
URL:https://ces.b2sg.org/event/27feb19/
LOCATION:National Institutes of Health (NIH) campus\, Bethesda\, MD\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20190227
DTEND;VALUE=DATE:20190331
DTSTAMP:20260904T144727
CREATED:20190227T131517Z
LAST-MODIFIED:20190227T134029Z
UID:21088-1551225600-1553990399@ces.b2sg.org
SUMMARY:Bioinformatics Specialist
DESCRIPTION:A Bioinformatics Specialist position is available in the lab of Prof. Peter D. Adams for ambitious\, independent and motivated candidates to join the team investigating the epigenetics of aging and cancer at Sanford-Burnham-Prebys Medical Discovery Institute\, San Diego. The successful candidate will use computational and bioinformatics approaches to investigate age-associated epigenetic events\, derived from mouse tissues and cell culture models\, are related to epigenetic hallmarks of aging and disease\, most notably cancer. Datasets will include ChIP-seq\, RNA-seq\, ATAC-seq\, DNA methyl-seq and other large-scale epigenomic and chromatin analyses\, including at the single-cell level\, as well as results from high throughput chemical and RNAi/CRISPR phenotypic screens. \nPrimary Responsibilities\n\n\n\nPerforms computational analysis and integration of large transcriptomic and epigenetic datasets\nProvides access of public genetic\, epigenetic and transcriptomic large datasets\, for integration with those datasets generated in the lab\nUtilizes existing lab data analysis pipelines\nBuilds new data analysis pipelines\, e.g. for single cell RNA-seq and ATAC-seq.\nManages large dataset storage\, in databases\, lab wiki and lab UCSC browser\nPresents results to lab members at weekly lab meetings\nPresents results and data within SBP\, local La Jolla meetings and national and international meetings\, as appropriate\nMaintains and initiates collaborations between Adams lab and other labs in SBP\, San Diego\, US and worldwide\n\n\n\nRequired Skills \nRequired Experience \n\n\n\nBachelor’s Degree in Bioinformatics\, Biostatistics\, or Life Sciences or equivalent studies AND a minimum of 5 years work experience OR a Master’s degree in Bioinformatics\, Biostatistics\, or Life Sciences or equivalent studies AND 3 years of work experience in related field OR Ph.D. in Computer Science\, Bioinformatics\, Biostatistics\, or Life Sciences or equivalent studies\, is required\nPh.D. degree in Computer Science\, Bioinformatics\, or Life Sciences or equivalent studies is preferred\nExperience or background in molecular biology or biochemistry is preferred\nExperience with Illumina NGS data analysis is preferred\nPrevious Postdoc training is not required\n\n\n\nKnowledge\, Skills and/or Abilities\n\nGeneral familiarity with wet lab assays\nExcellent bioinformatics and programming skills (e.g. Perl\, Python\, C/C++\, Java\, R or Web applications)\nStrong command of Linux/UNIX operating system\nStrong knowledge and skills in bioinformatics\, statistics and next-generation sequencing data analysis\nAbility to use current bioinformatics tools and have an in depth knowledge of advanced sequencing and array-based technologies\nCommunicates effectively and collaborates well with Principal Investigators and their team members\nHave strong organizational and problem-solving skills\nPossesses strong attention to detail\, analytical and time management skills\nExcellent communication and interpersonal skills\nEmbody the Institute’s core values of Commitment\, Collaboration\, Communication\, Community and Compassion
URL:https://ces.b2sg.org/event/sbp-27feb19/
LOCATION:Sanford Burnham Prebys Medical Discovery Institute\, 10901 N Torrey Pines Rd\, La Jolla\, CA\, 92037\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20190228
DTEND;VALUE=DATE:20190401
DTSTAMP:20260904T144727
CREATED:20190228T101141Z
LAST-MODIFIED:20190228T101141Z
UID:21092-1551312000-1554076799@ces.b2sg.org
SUMMARY:Research Associate - Biology
DESCRIPTION:The Disease Biology Group in the Protein Homeostasis Thematic Center of Excellence (PH TCOE) focuses on delivering novel cancer therapeutics by engaging E3 ubiquitin ligases for targeted protein degradation. We are seeking a highly motivated Research Associate with experience in molecular biology and state-of-the-art techniques of epigenetic profiling such as ATAC-seq and ChIP-seq. The successful candidate will work collaboratively in a multi-disciplinary environment to further our understanding of the molecular mechanism of action of our novel compounds and targets. Responsibilities will include to design and execute genetic and epigenetic studies in multiple disease models to support drug target validation\, mechanism of drug action\, biomarker discovery and potential drug combination strategies.  The successful candidate will have the opportunity to work closely with discovery project teams and scientists across the PH TCoE functional areas and to present his or her work at project team meetings and to the senior research leadership. \nProtein Homeostasis at Celgene \nThe PH TCoE at Celgene is one of the fundamental research and early development engines delivering therapeutics to patients.  As a thematic center\, the PH TCoE is agnostic to therapeutic modality or disease area. The group integrates discovery research through translational and early clinical development and focuses on numerous aspects of protein homeostasis including the ubiquitin-proteasome system\, protein translation\, and RNA processing and stability. This thematic focus allows the group to capitalize on the cutting edge science that underpins the action of the company’s most advanced drugs. Not being bound by disease area or therapeutic modality creates a very dynamic\, exciting and creative environment that exploits excellent science in biology\, biochemistry\, structural biology\, computational biology and translational development. \nResponsibilities will include\, but are not limited to the following: \nWork independently to design\, execute\, analyze\, interpret and troubleshoot scientific experiments in molecular and cell biology\, cellular biochemistry and assay development Accurately maintain written reports and present results in an organized and timely manner to supervisor and colleagues Communicate with peers and supervisors\, foster teamwork and contribute to collaborative efforts Strong commitment to quality and demonstrate adaptability \nSkills/Knowledge Required: \n\nBachelor’s degree in molecular biology\, cell biology\, or related scientific discipline with at least 2 years laboratory experience.\nHands-on experience with molecular biology techniques including but not limited to\, quantitative PCR\, ATAC-seq and ChIP-seq and manipulation/editing of gene/message/protein via RNAi and/or CRISPR methods\nExperience with mammalian cell culture and cell-based assays to analyze compound effects (Western blot\, ELISA\, immunoprecipitation\, immunofluorescence and functional assays such as cell cycle and apoptosis)\nExcellent communication\, presentation and organizational skills are required as well as the ability to independently design\, execute\, and troubleshoot experiments through completion\nData analysis skills and experience with a variety of scientific software applications are required\nAbility to work in a fast-paced dynamic team environment; flexibility to adapt to changes with a positive attitude.
URL:https://ces.b2sg.org/event/cel-28feb19/
LOCATION:Celgene\, 86 Morris Ave\, Summit\, NJ\, 07901\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20190301
DTEND;VALUE=DATE:20190402
DTSTAMP:20260904T144727
CREATED:20190301T224956Z
LAST-MODIFIED:20190301T225457Z
UID:21095-1551398400-1554163199@ces.b2sg.org
SUMMARY:Life Science Technician I
DESCRIPTION:Stanford University is seeking a Life Science Technician to perform techniques independently involved in cancer biology\, stem cell biology and molecular medicine. \n \nAbout the Department of Pathology\nComprised of extraordinary faculty and staff\, our mission is to improve the diagnosis\, treatment and basic understanding of human disease.  We accomplish this through our clinical services\, research\, and training the future leaders in pathology and related fields.  A major focus of clinical research in the Department continues to be the correlation of patient outcome and treatment response with the surgical pathologic diagnosis of human cancers.  Everything we do is to provide the highest quality of pathology diagnostic services to the patients for whom we passionately care. \n \nFor more information about the department visit http://pathology.stanford.edu/  \n  \nDescription:\nThe Department of Pathology\, Van Rechem Lab\, seeks a Life Science Technician 1 (LST-1) to assist with research projects in epigenetics and cancer. The LST-1 will perform routine technical tasks in cellular and molecular biology\, including cell culture maintenance\, FACS\, qPCR\, protein immunoblots\, cloning\, preparation and aliquote of reagents. The LST-1 will also assist in maintaining lab organization as needed. \n\n\nQualifications:\n\nApproximately one year of previous laboratory experience in molecular and/or cellular biology is required. Basic technical writing beneficial but not required.\nMust be capable of and willing to pay strict attention to detail\, including following written and oral instruction.\n\nFamiliarity with the following experimental techniques preferred:\n\n\n\n\nplasmid cloning\ntissue culture\nimmunohistochemistry (IHC) and/or immunofluorescence (IF)\nflow cytometry (FACS)\nWestern Blot\nQPCR\n\n\n\n\nMust be detail-oriented and able to keep accurate records of experiments.\nGeneral understanding of scientific principles.\nGeneral computer skills and ability to quickly learn.\nAbility to work under deadlines with general guidance.\nExcellent organizational skills and demonstrated ability to accurately complete detailed work.\n\n\nEDUCATION & EXPERIENCE (REQUIRED):\nOne year’s employment experience in laboratory work or equivalent training. \n \nKNOWLEDGE\, SKILLS AND ABILITIES (REQUIRED):\nMust be detail-oriented and able to keep accurate records of experiments.\nGeneral understanding of scientific principles.\nGeneral computer skills\, experience with databases.\nAbility to work under deadlines with general guidance is essential.\nExcellent organizational skills and demonstrated ability to complete detailed work accurately.\n \nPHYSICAL REQUIREMENTS*:\nFrequently stand\, walk\, twist\, bend\, stoop\, squat\, grasp lightly\, use fine manipulation\, grasp forcefully\, perform desk-based computer tasks\, use telephone\, write by hand\, lift\, carry\, push and pull objects weighing over 40 pounds.\nOccasionally sit\, kneel\, crawl\, reach and work above shoulders\, sort and file paperwork or parts.\nMust have correctible vision to perform duties of the job.\nAbility to bend\, squat\, kneel\, stand\, reach above shoulder level\, and move on hard surfaces for up to eight hours.
URL:https://ces.b2sg.org/event/1mar19/
LOCATION:Stanford University\, School of Medicine\, 291 Campus Drive\, Stanford\, CA\, 94305\, United States
CATEGORIES:Jobs
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