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METHOD:PUBLISH
X-WR-CALNAME:Cancer Epigenetics Society
X-ORIGINAL-URL:https://ces.b2sg.org
X-WR-CALDESC:Events for Cancer Epigenetics Society
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TZID:Europe/Paris
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TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:CEST
DTSTART:20190331T010000
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TZOFFSETFROM:+0200
TZOFFSETTO:+0100
TZNAME:CET
DTSTART:20191027T010000
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20190323
DTEND;VALUE=DATE:20190425
DTSTAMP:20260906T163017
CREATED:20190323T151159Z
LAST-MODIFIED:20190323T151159Z
UID:21130-1553299200-1556150399@ces.b2sg.org
SUMMARY:Research Fellow
DESCRIPTION:Dr. Oser is seeking a highly motivated and qualified postdoctoral candidate interested in pursuing several projects aimed at identifying new therapeutic targets for SCLC.\n\nThe position will require a core foundation of molecular and cellular biology\, tissue culture\, and some basic training in mouse modeling and epigenetics.\n\nThe successful candidate will be expected to lead and develop several independent projects.\n\n\n\nQualifications\n\n\n\nThe candidate must have a MD\, PhD or MD/PhD with several years of relevant experience in molecular biology with some research experience in cancer biology.
URL:https://ces.b2sg.org/event/23mar19/
LOCATION:Dana-Farber Cancer Institute\, 450 Brookline Avenue\, Boston\, MA\, 02215\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/11/Dana-Farber.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20190324
DTEND;VALUE=DATE:20190426
DTSTAMP:20260906T163017
CREATED:20190324T194116Z
LAST-MODIFIED:20190324T194116Z
UID:21132-1553385600-1556236799@ces.b2sg.org
SUMMARY:Senior Scientist\, Molecular Discovery
DESCRIPTION:This senior scientist will join the Integrative Biotechnology Group of the Pfizer Oncology Research Department where s/he will apply functional genomics to study cellular mechanisms that impact tumor response to late stage oncology pipeline assets. \nThe qualified candidate should be a highly motivated\, creative\, and collaborative individual with strong interest and publication record relevant to tumor intrinsic / extrinsic signaling regulating cell cycle progression\, epigenetics\, and/or senescence response. The candidate must be flexible to study novel mechanisms underlying tumor vulnerabilities discovered from functional genomics screening efforts. This role includes developing and applying flow cytometry based biological endpoint assays to enable prioritization of screen hits that elicit desired outcome. \nThe successful candidate must have strong communication skills and will be expected to present their research to multidisciplinary teams\, senior management\, and at external scientific meetings. \nROLE RESPONSIBILITIES  \n\nDevelop and execute assays for in vitro / in vivo synthetic lethal functional genomics screens in relevant cancer models to discover genes that impact sensitivity or resistance to late stage oncology compounds.\nPrioritize drug discovery opportunities by integrating screen results with knowledge gained from publicly available datasets and multi-omics profiling of tumor response to small molecule inhibitors.\nCollaborate with a diverse team of cancer and molecular biologists to validate and determine the mechanism of action of prioritized targets.\nIncorporate advances in CRISPR/RNAi technologies to maintain cutting edge functional genomics platform.\nPresent key findings that highlight research progress and opportunities to senior management and at internal meetings.\nContinue excellent publication and presentation record by publishing research discoveries in high impact journals and presenting at external scientific conferences.\n\nBASIC QUALIFICATIONS  \n\nPh.D. in Cell Biology or related discipline and 3+ years of academic experience at the postdoctoral level or 2+ years of industry experience in cancer research.\nBroad understanding of and advanced technical expertise in research of signaling pathways that underlie cell cycle progression\, epigenetics\, and/or mechanisms that govern senescence.\n\nPREFERRED QUALIFICATIONS \n\nExperience executing pooled CRISPR/RNAi screens in cancer models in vitro and / or in vivo.\nStrong technical expertise in flow cytometry / sorting.\nDeveloped/applied biological endpoint assays to gain mechanistic insights into the consequences of gene knockdown or inhibition.\nExperience working with 2D and 3D mammalian cell culture systems.\nExpert molecular biology skills as well as expertise in immunofluorescence\, immunoprecipitation\, transgene mutagenesis / expression\, western blot\, and Q-PCR.\nSignificant impact in field of study as demonstrated by publications in top tier peer-reviewed research journals.
URL:https://ces.b2sg.org/event/24mar19/
LOCATION:Pfizer – Pearl River\, NY\, 401 North Middletown Road\, Pearl River\, NY\, 10965\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2018/05/pfizer_new_logo.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20190325
DTEND;VALUE=DATE:20190427
DTSTAMP:20260906T163017
CREATED:20190325T131859Z
LAST-MODIFIED:20190325T131859Z
UID:21134-1553472000-1556323199@ces.b2sg.org
SUMMARY:Postdoctoral Research Associate
DESCRIPTION:Multiple postdoctoral research associate positions available for highly motivated candidates with a fresh PhD training in molecular biology\, biochemistry and cell biology to join the Lineberger Comprehensive Cancer Center and Department of Biochemistry\, University of North Carolina at Chapel Hill (UNC) School of Medicine\, USA. Our lab (http://www.gregwanglab.com) emphasizes on mechanistic understandings of gene regulation\, chromatin\, stem cells\, and human disease notably cancer. We have recently published our findings at various gene regulatory mechanisms\, including those related to DNA methyltransferase and histone modifying enzymes\, at Molecular Cell (2013); Blood (2015); Cell Reports (2015); Cancer Cell 2016; Nature (2018); Stem Cell Reports (2018) and Molecular Cell (2018). With recent acquisition of funds from NIH and NCI\, we have multiple positions available for 1) Bioinformatics associate focused on computation analysis of genomics dataset 2) Postdoctoral associates focused on experimental biology The on-going projects include (1) biochemical characterization of epigenetic factors/complexes that regulate gene expression in stem cells or cancer cells; (2) CRISPR/dCas9-based editing and screening of pathways crucial for cancer development; (3) knockout and knock-in mouse models with deficiency in histone /DNA methylation regulation in context of development and tumorigenesis\, with a special focus on hematopoietic disease; (4) epigenomic and transcriptome analyses (ChIP-Seq and RNA-Seq) of normal versus cancer cells to understand 3D chromatin structure and to delineate pathways essential for tumor growth. \n\n\n\n\nMinimum Qualifications: \nApplicants should be self-motivated with a track record of publication in the above area\, have laboratory and analytical skills\, and be a critical thinker. Application shall include CV\, a cover letter (with summary of research experiences and future interests\, and expected availability date)\, reprints of publications\, and contact information of three references.   Ph.D. training in molecular biology\, cell biology or biochemistry related field.
URL:https://ces.b2sg.org/event/25mar19/
LOCATION:University of North Carolina – UNC-Chapel Hill\, Chapel Hill\, NC\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20190327
DTEND;VALUE=DATE:20190429
DTSTAMP:20260906T163017
CREATED:20190327T171057Z
LAST-MODIFIED:20190327T213323Z
UID:21137-1553644800-1556495999@ces.b2sg.org
SUMMARY:Research Professional 2
DESCRIPTION:The research professional will conduct research in aspects of chemical carcinogenesis\, epigenetics\, and chemical biology relevant to our ongoing studies of DNA adducts and epigenetic deregulation in lung cancer. This position is expected to provide daily support to the research activities in the laboratory by conducting cell culture and animal experiments in support of many ongoing projects\, lab organization\, documentation\, and supply orders. \nPrincipal Duties and Responsibilities:\n40 % Cell culture experiments\nMaintain mammalian cell culture\, Conduct cell culture treatments\, extract proteins\, RNA\, DNA \n30 % Management of the research laboratory\nTake care of supply orders\, lab organization\, support smooth operation of the lab. \n15% Animal experiments\nOperate animal exposures\, collect tissues\, extract proteins\, RNA\, DNA \n10 % Record-keeping and Preparation of Manuscripts\nMaintaining detailed laboratory records; preparing data for manuscripts and presentations. \n5% Training Graduate and Undergraduate Students\nTraining of students in proper cell culture techniques \nSupervision:\nResearch professional will be trained by\, and work in conjunction with a faculty mentor (Natalia Tretyakova) who determines the training agenda. They report to Natalia Tretyakova. \nThe Department of Medicinal Chemistry consists of a diverse group of faculty members\, graduate students and postdoctoral fellows\, and research scientists working at the interface of chemistry and biology and is home to the editorial offices of the Journal of Medicinal Chemistry and ACS Infectious Diseases. \nThe department is part of the College of Pharmacy and Academic Health Center\, which house nationally and internationally acclaimed programs in the areas of biochemistry\, neuroscience\, pharmacology\, virology\, immunology\, cancer biology\, structural biology\, and drug delivery. \nApplications must be submitted online. To be considered for this position\, please click the Apply button and follow the instructions. You will be given the opportunity to complete an online application for the position and attach a cover letter and resume. \nAdditional documents may be attached after application by accessing your “My Job Applications” page and uploading documents in the “My Cover Letters and Attachments” section. \nTo request an accommodation during the application process\, please e-mail employ@umn.edu or call (612) 624-UOHR (8647).
URL:https://ces.b2sg.org/event/27mar19/
LOCATION:MA
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20190328
DTEND;VALUE=DATE:20190430
DTSTAMP:20260906T163017
CREATED:20190328T194943Z
LAST-MODIFIED:20190328T194943Z
UID:21145-1553731200-1556582399@ces.b2sg.org
SUMMARY:Scientist (non-PhD)
DESCRIPTION:Pfizer is seeking applications for an exceptional non-PhD scientist with chemical biology\, cell biology and mass spectrometry-based proteomics experience. Such a candidate will be a highly motivated and creative scientist with the desire to join and support chemical biology and proteomics capabilities for our oncology pipeline. This person will align across Pfizer’s tumor cell biology groups enabling impact across the small molecule oncology portfolio from early exploratory target identification through the drug discovery pipeline and into early clinical development.  \nThe individual will support and aid in the development and application of chemical biology and innovative mass spectrometry platforms. Their work will drive a deeper understanding of our molecules and cellular targets. Relevant methodologies include but are not limited to: identification of novel oncology targets\, small molecule target deconvolution\, small molecule target occupancy studies using chemical probes\, direct substrate identification and characterization\, protein turnover studies\, protein post-translation modification studies and small molecule–protein interactome analyses. \nROLE RESPONSIBILITIES  \n\nApply quantitative protein mass spectrometry technologies for chemo-proteomics and general proteomics across the oncology portfolio.\nParticipate in all aspects of laboratory operations including sample preparation\, running samples on the MS\, data analysis and interpretation.\nDevelopment of methods for direct identification of kinase substrates.\nPresenting and reporting data with follow up discussions for project teams including data impact and interpretation.\nComplete and effectively manage multiple projects within timelines ensuring that all tasks and responsibilities are carried out according to high scientific and ethical standards.\nEngage in collaborative and strategic partnerships with internal research teams to apply proteomics for oncology discovery\, impacting all oncology research focuses including: Systems Therapeutics\, Tumor Intrinsic Biology\, Immuno-oncology and Epigenetics.\n\nBASIC QUALIFICATIONS \n\nA qualified applicant holds a M.S/B.S. in biological sciences\, chemical biology\, analytical chemistry\, or a related field.\n6+ years of research experience with applied cell biology\, chemical biology and mass spectrometry-based proteomics desired.\nExpertise in growing\, maintaining and harvesting cancer cells lines.\nGeneral understanding of chemical proteomics methodologies including small-molecule affinity enrichment\, target occupancy and Chem-Seq. \nGeneral understanding of target deconvolution methods including CETSA\, DARTS\, FUSION and chemical probes/proteomics.\nExcellent verbal and written communication skills.\nKnowledge and application of complex sample preparation methodologies as applied to protein mass spectrometry workflows.\nAbility and understanding of methods to characterize protein post-translational modifications including phosphorylation\, methylation\, acetylation\, PARylation and ubiquitination.\nExperience and knowledge in the operation of different types of mass spectrometers including Q Exactive Hybrid Quadrupole and Orbitrap Fusion Lumos Tribrid.
URL:https://ces.b2sg.org/event/28mar19/
LOCATION:Pfizer – La Jolla\, CA\, 10350 N Torrey Pines Rd\, La Jolla\, CA\, 92037\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20190329
DTEND;VALUE=DATE:20190501
DTSTAMP:20260906T163017
CREATED:20190329T075153Z
LAST-MODIFIED:20190329T075153Z
UID:21147-1553817600-1556668799@ces.b2sg.org
SUMMARY:Research Specialist
DESCRIPTION:A Research Specialist position is available in the Benevolenskaya lab with Department of Biochemistry and Molecular Genetics at the University of Illinois at Chicago /College of Medicine. The laboratory is broadly interested in tumor suppressor genes and epigenetic mechanisms. Research in the lab focuses on the histone demethylase KDM5A and is aimed at better understanding of the roles played by pRB and KDM5A in cell metabolism and differentiation.  \nIdeal candidate is expected to contribute to research done in the laboratory\, including the design\, execution and data analysis of experiments. Job duties include using cellular and animal models\, cellular and molecular biology techniques such CRISPR/Cas gene editing\, SDS-PAGE\, Western blotting\, PCR\, gene cloning\, and lab management.  \nBachelor’s degree in basic science and 3 years of experience in biochemistry\, molecular genetics or cancer biology. Master’s degree in science is preferred. \nRecent graduates are highly encouraged to apply. Interested candidates should send their curriculum vitae\, the names of 3 references via the University electronic application process at https://jobs.uic.edu/job-board/job-details?jobID=111435 by April 12\, 2019.  UIC is an Equal Opportunity\, Affirmative Action employer.  Minorities\, women\, veterans and individuals with disabilities are encouraged to apply. 
URL:https://ces.b2sg.org/event/29mar19/
LOCATION:University of Illinois at Chicago\, Chicago\, IL\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20190330
DTEND;VALUE=DATE:20190502
DTSTAMP:20260906T163017
CREATED:20190330T162853Z
LAST-MODIFIED:20190330T162853Z
UID:21149-1553904000-1556755199@ces.b2sg.org
SUMMARY:Research Scientist
DESCRIPTION:Multiple Myeloma is a cancer of the blood system. Clinically there has been much progress in improving outcomes but 30% of cases have aggressive clinical disease that does not respond well to therapy and new-targeted therapies are required to address this. The Multiple Myeloma Program at NYU is a new initiative to understand the biology and develop new therapies for this devastating illness. Major aims of the program are to utilize biological knowledge to treat high-risk disease and to prevent the development of the disease by manipulating the evolutionary trajectory of its premalignant precursor phases\, which are common in the general population. To achieve these aims we will focus on three main areas studying the epigenetic basis of disease progression\, the role of complex genetic structural rearrangements and the impact these have on the bone marrow microenvironment. We will use advanced genetic technologies to study the biology of these different areas. The person in this position will play an important role in the program being responsible for establishing a robust research environment\, coordinating activities in the laboratory\, inputting into the coordination\, receipt and processing of clinical samples and establishing new technologies to meet the needs of the program. The position will require a sound knowledge and expertise in molecular genetic techniques and cell culture. The laboratory benefits from the vibrant scientific environment\, collaboration with leading researchers and an outstanding medical school infrastructure that supports the most advanced technologies. Responsible for collaborating with Principal Investigators (PI) and working independently within the scientific framework of the PIs Laboratory. \n\n\nJob Responsibilities: \n\nDemonstrates knowledge of the organizations Core Values and incorporates them into the performance of duties.\nInitiates\, interprets\, organizes\, executes\, and coordinates research assignments critical to departments mission.\nFormulates and conducts research on problems of considerable scope and complexity.\nExplores subject area and defines scope and selection of problems for investigation through conceptually related studies or series of projects of lesser scope.\nMakes decisions and recommendations that have a major impact on extensive scientific research activities.\nDevelops new ideas that promote current research. Exercises a high degree of creativity\, foresight\, and mature judgment in planning\, organizing\, and guiding extensive scientific research programs and activities of outstanding novelty and/or importance.\nMay manage the operations of a lab for the Principal Investigator by supervising Post Docs and technicians. Oversees the maintenance and upkeep of all instruments and laboratory facilities.\nEnsures timely and accurate completion of research projects.\nMay provide students with technical guidance and direction in the operation of various sample preparation techniques\, extraction of cell lines\, and equipment as well as general laboratory practices and safety protocols.\nMay seek grant funding from external sources in support of their independent research projects with consent of the PI and the Department Chair. May participate in writing grant proposals.\nMay be responsible for research/lab quality control and compliance.\nMay develop protocols for the collection and quality of research data.\nDevelops research techniques and methodologies.\nMay determine and establish laboratory policies\, procedures and practices.\nMaintains a thorough knowledge of the advances in specialized fields through attendance of scientific conferences.\nMay make significant contributions to scientific paper writing and act as a resource/ author/ co-author for reports and presentations.\nMay provide recommendations for equipment purchases and for the redesign of lab space.\nMay coordinate the activity and experimental design between various labs\, scientific staff\, and collaborators. Identifies and resolves technical problems.\nMay serve on internal committees to help further goals of research projects and bring new expertise to the research program.\nPerforms other related duties as assigned.\n\n\n\nMinimum Qualifications:\nTo qualify you must have a MS degree and 2-4 years of experience. \n\n\nPreferred Qualifications:\nSubstantial experience from having completed Post Doc training. Established a record of publications. PhD Degree\nExperience:\nMolecular genetic skills\nExperience with PDX models\nCell culture \n\n\nQualified candidates must be able to effectively communicate with all levels of the organization.
URL:https://ces.b2sg.org/event/30mar19/
LOCATION:NYU School of Medicine\, 550 1st Avenue\, New York\, NY\, 10016\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20190331
DTEND;VALUE=DATE:20190502
DTSTAMP:20260906T163017
CREATED:20190331T183936Z
LAST-MODIFIED:20190331T183936Z
UID:21151-1553990400-1556755199@ces.b2sg.org
SUMMARY:Oncology Medical Science Liaisons
DESCRIPTION:Are you interested in being a part of an exciting new Oncology MSL launch team?  GSK is hiring in the following territories! We are looking for motivated individuals who want to be a part of an amazing culture that fosters growth and help build a team from the ground up.  At least 2 years of oncology MSL experience is required along with an advanced degree (PharmD\, PhD\, MD).  \n\nMSL Oncology (Rochester\, MN/Minneapolis\, MN) \n\nhttps://gsk.wd5.myworkdayjobs…. \n\nMSL Oncology (Baltimore\, MD/Washington\, DC) \n\nhttps://gsk.wd5.myworkdayjobs…. \n\nMSL Oncology (New York\, NY) \n\nhttps://gsk.wd5.myworkdayjobs…. \n\n\nMSL Oncology (Nashville\, TN) \n\nhttps://gsk.wd5.myworkdayjobs…. \n\nMSL Oncology (Columbus\, OH/Cleveland\, OH) \n\nhttps://gsk.wd5.myworkdayjobs…. \n\nMSL Oncology (Boston\, MA) \n\nhttps://gsk.wd5.myworkdayjobs…. \n\nGSK Oncology is committed to the discovery and development of new and potentially life-changing therapies for patients with cancer. Our vision is for people with cancer to not only to live\, but to live well\, because we are delivering innovative and transformational medicines.  We have strictly focused our portfolio on innovation with a focus on the leading edges of science: immuno-oncology\, cell therapy and epigenetics.  Our deep insight into cancer biology coupled with strategic partnerships will allow us to develop synergistic combinations with transformational potential.    \nOn December 3\, 2018 we announced our agreement to acquire TESARO\, an oncology-focused company based in the US.  The proposed transaction will significantly strengthen our pharmaceutical business\, accelerating the build of our pipeline and commercial capability in oncology.
URL:https://ces.b2sg.org/event/gsk31mar19/
LOCATION:gsk\, 1250 S Collegeville Rd\, Collegeville\, PA\, 19426\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20190401
DTEND;VALUE=DATE:20190503
DTSTAMP:20260906T163017
CREATED:20190401T201043Z
LAST-MODIFIED:20190401T201123Z
UID:21153-1554076800-1556841599@ces.b2sg.org
SUMMARY:Associate Director - Cancer Biology
DESCRIPTION:Agios (agios.com) is a biopharmaceutical company driven to discover and develop transformative therapies for cancer and rare genetic disease. Agios is growing rapidly\, having recently secured approval of a first-in-class oncology precision medicine\, with multiple additional novel investigational therapies in development and a robust drug discovery pipeline. We continue to build upon our scientific leadership in dysregulated metabolism as we seek precision medicines in metabolism and adjacent biology areas. In oncology\, Agios strives to uncover\, characterize and drug novel targets with robust patient selection strategies and potential for rapid\, biomarker-driven clinical development. \nIn this role\, you will bring your project and people leadership to our dynamic company.  We are looking for a highly motivated and skilled leader with a strong background in oncology and drug discovery to join our team. \nKey Responsibilities \n\nDevises and oversees the cell biology efforts for novel oncology therapeutic program(s)\nEnsures timely delivery of incisive and actionable biology data that defines/refines drug discovery strategy\nServes as a target champion and internal expert in disease biology for one or more oncology drug discovery programs\nDevises and executes cancer biology experiments to support projects from validation to clinical candidate selection\nLeads cross-functional team efforts for hit-to-lead and lead-op stage drug discovery program(s)\nManages the work of multiple internal biologists and leverages CROs and academic collaborators effectively to drive program science forward\nPropagates a development-oriented culture & champions the growth of a talented and aspirational team of cancer biologists\nMaintains high-functioning and synergistic cross-functional relationships across the Agios discovery organization\nCommunicates science and strategy effectively in a variety of internal and external settings\n\nQualifications \n\nPh.D. in cancer biology or related field with 8+ years of industry experience\nDemonstrated success as a lead biologist advancing novel\, first-in-class therapeutics through hit-finding and lead optimization. Experience with IND-enabling studies is desired\nExpertise in cancer epigenetics is highly preferable\nPrior experience managing and mentoring direct reports and working with international CROs\nExcellent verbal and written communication and interpersonal skills to work across functions and within external collaborations\, and a demonstrated ability to organize and communicate complex data sets in a clear and concise manner to cross-functional audiences\nStrong organizational and time-management skills and demonstrated ability to lead cross-functional collaborations including managing relationships with academic collaborators and CROs\nDesire and capacity to participate in a dynamic and fast-paced research setting\nRecognized scientific innovation and accomplishment evidenced by strong record of publication and conference presentations in cancer biology
URL:https://ces.b2sg.org/event/1apr19/
LOCATION:Agios Pharmaceuticals\, 88 Sidney Street\, Cambridge\, MA\, 02139\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20190403
DTEND;VALUE=DATE:20190506
DTSTAMP:20260906T163017
CREATED:20190403T121044Z
LAST-MODIFIED:20190403T121122Z
UID:21158-1554249600-1557100799@ces.b2sg.org
SUMMARY:Sr. Research Associate - Assay Development
DESCRIPTION:To enable Guardant Health to lead the disruption of cancer treatments through non-invasive cancer screening\, the Technology Development Team is seeking a highly motivated Senior Research Associate to help develop\, test\, and improve sample preparation technologies for rare variant and epigenetic studies with next-generation sequencing. At Guardant\, we leverage the most advanced technologies and work with leaders in many different fields to create the most impactful and meaningful technologies for cancer management. \nAs a Senior Research Associate supporting product and technology development\, you will work with members within the team and interface with multiple teams including process engineering\, clinical operations\, research operations\, and bioinformatics. You will be hands on in the lab and be required to design\, implement\, and validate new technologies related to liquid biopsy sequencing assays for the early detection\, treatment\, and monitoring of all cancer types. \nEssential Duties and Responsibilities: \n\nOperate next generation sequencing instruments\nRun sequencing sample preparation assays in medium to high throughput environment\nTest and improve new sequencing sample preparation assays\nLog and track research samples throughout sequencing workflow\nMaintain appropriate inventory of lab supplies\nBring a can do attitude to solve new and challenging problems in a high pace environment\nAnalyze data and troubleshoot issues within the tech dev team and among other teams\nCollaborate with all functions within project teams\nEngage in early design of products and perform experiments both independently and under the supervision of Senior team members within Tech Dev and Bioinformatics groups\nBe able to present updates\, write reports and SOPs\, and contribute to technical discussions\n\n\n\nQualifications \nQualifications: \n\n5-7 years of related experience\nThe ability to handle biological samples (i.e. tissue\, biofluid\, etc) is a must\nExcellent written and oral communication skills is a must\nProfessional hands-on experience in industrial setting in genomics field is a plus (operational experience is preferred)\nHands-on experience in running sequencing platforms and assays is a plus\nExperience with process automation for nucleic acid extraction and sample preparation is a plus\nLocal candidates in San Francisco Bay area are preferred.\n\nEducation: \nBSc\, MSc or Ph.D. in Molecular Biology\, Bioengineering\, Biochemistry or related field
URL:https://ces.b2sg.org/event/guardant3apr19/
LOCATION:Guardant Health\, 505 Penobscot Dr.\, Redwood City\, CA\, 94063\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20190404
DTEND;VALUE=DATE:20190507
DTSTAMP:20260906T163017
CREATED:20190404T073037Z
LAST-MODIFIED:20190404T073037Z
UID:21171-1554336000-1557187199@ces.b2sg.org
SUMMARY:Associate Director/Director – Epigenetics Lead\, Oncology Bioscience
DESCRIPTION:We are seeking a highly motivated and skilled bioscience leader with a strong oncology epigenetics background and publication record to join the Oncology Bioscience team at AstraZeneca in Waltham\, MA. As an Associate Director/Director – Epigenetics Lead you will lead existing epigenetics programs in the oncology discovery and development portfolio and directly line manage a team of in vitro/cell biologists. You will also oversee identification and validation of novel epigenetics targets\, assay development and compound profiling\, studies to evaluate compound mechanistic of action and experiments to develop hypotheses to support disease positioning and patient selection for clinical development. Additionally\, you will further develop and lead the global oncology epigenetics strategy working with other AstraZeneca science leaders across disciplines and manage external collaborations in this area \nMajor Responsibilities: \n\nDevelop and lead a global oncology epigenetics strategy to ensure a sustainable portfolio of targets and projects through internal efforts and external collaborations\nOversee non-clinical support for existing epigenetics programs as part of cross discipline project teams\nManage a team of scientists\, setting their goals and objectives and providing appropriate development opportunities.\nMaintain an understanding and awareness of internal and external developments that could affect the discipline and share this with team members\nIdentify new drug development opportunities and convey ideas to team members to foster a working environment that promotes science and encourages innovation on drug discovery projects\nProvide routine updates and presentations to Oncology senior leadership teams\nBe an active member of the Oncology Bioscience leadership team contributing to and influencing strategic direction and capability development\nBuild networks with other leaders and external experts to learn about new developments\, leveraging opportunities and share best practices\nEnsure that own work and work of your team is of a high ethical standard\, Good Laboratory Practice\, Safety Health and Environment standards and all other relevant internal and external regulation and standards.\n\nEssential Requirements: \n\nA PhD in Oncology or equivalent experience in a relevant area of cancer biology\nExtensive experience within the pharmaceutical/biotech industry and the drug discovery process across different project stages and/or academic experience in oncology epigenetics\nExtensive knowledge of epigenetics\, ideally cancer epigenetics with a strong publication record in this area\nExperience in managing scientists and performance\, either as a team leader or within a matrix environment\nProven ability to be an effective within multidisciplinary teams\nExperience providing innovative solutions to complex problems with drug discovery projects.\nOutstanding oral presentation and written communication skills
URL:https://ces.b2sg.org/event/4apr19/
LOCATION:AstraZeneca\, Gaithersburg\, MD\, 20878\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20190405
DTEND;VALUE=DATE:20190508
DTSTAMP:20260906T163017
CREATED:20190405T081855Z
LAST-MODIFIED:20190405T081855Z
UID:21175-1554422400-1557273599@ces.b2sg.org
SUMMARY:Assistant/Associate Professor- Epidemiology
DESCRIPTION:Epidemiologist sought for independent tenure-track (or non-tenured) faculty position at the Assistant\, Associate Professor level in the Population Neuroscience core at the Glenn Biggs Institute for Alzheimer’s & Neurodegenerative Diseases (Biggs Institute) at the UT Health San Antonio (UTHSA). \n\nThe Biggs Institute is being established as a flagship\, free-standing institute within UTHSA with the mission of establishing an interdisciplinary\, integrated program to provide comprehensive clinical care and undertake innovative and important research into the prevention and treatment of Alzheimer’s Disease and other neurodegenerative conditions\, including vascular contributions to dementia\, Parkinson’s disease and frontotemporal dementia. It has strong institutional and community support and will benefit from existing resources within UTHSA such as the Barshop Institute for Longevity and Aging Studies\, the Center for Biomedical Neuroscience\, the School of Nursing\, the Cancer Center\, and the Research Imaging Institute along with the San Antonio campus of the UT Health Houston School of Public Health. \n\nIn addition\, there will be opportunities for immersive\, collaborative research within the Framingham Heart Study\, the Cohorts for Heart and Aging Research in Genomic Epidemiology\, the Cross-Cohorts Collaboration Consortium\, the International Genomics of Alzheimer’s Project\, the Alzheimer’s Disease Sequencing Project\, the International Stroke Genetics Consortium and other consortia in which the founding director of the Biggs Institute\, Dr. Sudha Seshadri\, has a leadership role. \n\nThe Biggs Institute will be comprised of 5 closely integrated cores: a Clinical Care and Clinical Research Core\, a Population Neuroscience Core\, a Biological and Innovative Research Core\, an Education\, Ethics and Training Core and a Public Health\, Policy and Community Engagement Core. \n\nWe are looking for visionary\, dynamic faculty who will enjoy working hard\, leading and collaborating across disciplines\, schools\, national and international networks. Salary and benefits will be competitive and commensurate with education\, experience and publication and research funding track record. \n\nWe are seeking an epidemiologist with a doctoral degree and 2 or more years of experience in one or more of various areas of neuro-epidemiology including\, but not limited to neuroimaging (MRI\, PET)\, circulating\, CSF and other biomarkers\, vascular and metabolic risk factors\, lifestyle (such as diet\, physical activity\, sleep\, social networks and cognitive engagement)\, life-course approaches\, environmental (pollution\, built environment)\, stroke\, aging\, risk modeling and risk prediction\, genetics\, epigenetics and other omics (including metabolomics\, proteomics\, microbiome) approaches to population neuroscience. \n\nThe appointment will be with the Biggs Institute with a cross appointment within the most suitable/preferred academic department at UTHSA based on the candidate’s specialization and background\, e.g. epidemiology\, neuroimaging\, genetics. Additional teaching and administrative leadership opportunities may be negotiated in this parent academic department. The selected candidate will report directly to Drs. Seshadri and to the Chair of the selected academic department. For most candidates this academic appointment is likely to be in the Division of Epidemiology\, Department of Epidemiology and Biostatistics and the selected candidate will report directly to Drs. Seshadri and Ramirez\, Interim Chair of the Department of Epidemiology and Biostatistics. \n\nFor full consideration\, please visit the UT Health Careers Faculty applicant portal at: http://uthscsa.edu/hr/employment.asp to apply for position # 19000653 and upload 1) a cover letter stating career goals and the relevance of the candidate’s training and experience to the position; 2) a current CV; 3) a personal statement describing the candidate’s research plan and teaching experience; and 4) names and contact information of three references.
URL:https://ces.b2sg.org/event/5apr19/
LOCATION:UT Health Science Center in San Antonio\, 7703 Floyd Curl Drive\, San Antonio\, TX\, 78229\, United States
CATEGORIES:Jobs
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DTSTART;VALUE=DATE:20190406
DTEND;VALUE=DATE:20190509
DTSTAMP:20260906T163017
CREATED:20190406T173130Z
LAST-MODIFIED:20190406T173130Z
UID:21185-1554508800-1557359999@ces.b2sg.org
SUMMARY:Postdoctoral Research Associate
DESCRIPTION:Postdoctoral positions in bone biology and epigenetics are available immediately at the University of Southern California/Norris Comprehensive Cancer.  Specifically\, our projects are aimed at understanding how histone modifications and chromatin factors influence epigenetic pathways in osteoclast differentiation.  Successful applicants will be self-driven and highly motivated individuals with established track records of success\, including first-author publications. \nMinimum education and experience \nPh.D. or equivalent doctorate within previous three years \nAnalysis\nAssessment/evaluation\nCommunication—written and oral skills\nOrganization\nPlanning\nProblem identification and resolution\nProject management\nResearch
URL:https://ces.b2sg.org/event/6apr19/
LOCATION:University of Southern California\, Los Angeles\, CA\, 90007\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20190407
DTEND;VALUE=DATE:20190510
DTSTAMP:20260906T163017
CREATED:20190407T201951Z
LAST-MODIFIED:20190407T201951Z
UID:21188-1554595200-1557446399@ces.b2sg.org
SUMMARY:Postdoctoral Research Associate- Obstetrics & Gynecology
DESCRIPTION:The laboratory of Dr. Melissa Herbst-Kralovetz\, as a part of a translational research program in the Department of Obstetrics and Gynecology at the University of Arizona College of Medicine-Phoenix\, invites applicants to apply for a challenging and rewarding opportunity to contribute as a Postdoctoral Research Associate. The successful candidate will study the microbiota composition\, and inflammatory profile as it relates to mucosal homeostasis of the female reproductive tract. The research couples clinical and translational research to advance women’s health. This position allows for the opportunity to work closely within an interdisciplinary and translational research team on a variety of diseases. For more information on the Herbst-Kralovetz laboratory\, see http://herbstkralovetzlab.weebly.com/. \nThe Department of Obstetrics and Gynecology is composed of employed and private practice physicians creating a unique hybrid model. The faculty supports the OB/GYN residency program\, and is actively engaged in research and mentoring with interests ranging from general gynecology and obstetrics to subspecialties. Areas of interest include maternal-fetal medicine\, vaginal dysbiosis\, gynecologic oncology\, reproductive endocrinology and infertility\, sexual health\, urogynecology and pelvic pain. Additional departments include the Department of Basic Medical Sciences\, which is a multidisciplinary unit composed of faculty with research interests in cardiac and vascular biology; developmental\, cell and molecular biology; evolution of vertebrate morphology; gene environment interactions and epigenetics; host-microbe interactions and immunology; medical education; platform development\, medical devices and procedures; and signaling and steroid biology. In addition\, the Center for Applied NanoBioscience and Medicine and affiliate institutions such as the Translational Genomics Research Institute\, Phoenix Children’s Hospital\, St. Joseph’s Hospital/Barrow Neurological Institute and the Arizona Alzheimer’s Consortium offer abundant opportunities for collaborative research efforts. \n\nDuties & Responsibilities: \n\nStudy host-microbe interactions as it relates to the female reproductive tract.\n\n\nProcessing and analyzing clinical specimens for multi-omics analyses.\n\n\nAnalyze\, organize and report data for presentation and publications.\n\n\nProvide status reports in the form of laboratory meetings.\n\n\nBioinformatics/biostatistical knowledge and application.\n\n\nParticipate in grant applications and submit fellowship applications.\n\n\nKnowledge\, Skills\, & Abilities: \n\nSkill utilizing protein assays (Western blot and ELISA) and nucleic acid-based assays (extraction\, RT-PCR assays\, quantification\, etc.) and standard molecular biology techniques.\n\n\nExcellent writing and verbal skills as evidenced by prior publications and presentations in the area of Microbiology/Virology and/or Immunology.\n\n\nResourceful\, self-motivated and possess a proven record of scientific advances in the form of publications.\n\n\nKnowledge of microbiology/virology\, cell biology and immunology and related techniques.\n\n\nAbility to work in an interdisciplinary team environment.\n\n\nBiostatistical analysis of data sets.\n\n\nMinimum Qualifications: \nMD\, PhD or MD/PhD degree in Microbiology\, Virology\, Immunology\, Bioinformatics\, Computational Biology or Genetics.
URL:https://ces.b2sg.org/event/7apr19/
LOCATION:University of Arizona\, Tuscon\, AZ\, 85721\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20190408
DTEND;VALUE=DATE:20190511
DTSTAMP:20260906T163017
CREATED:20190408T174835Z
LAST-MODIFIED:20190408T174835Z
UID:21190-1554681600-1557532799@ces.b2sg.org
SUMMARY:Bioinformatics Specialist
DESCRIPTION:A Bioinformatics Specialist position is available in the lab of Prof. Peter D. Adams for ambitious\, independent and motivated candidates to join the team investigating the epigenetics of aging and cancer at Sanford-Burnham-Prebys Medical Discovery Institute\, San Diego. The successful candidate will use computational and bioinformatics approaches to investigate age-associated epigenetic events\, derived from mouse tissues and cell culture models\, are related to epigenetic hallmarks of aging and disease\, most notably cancer. Datasets will include ChIP-seq\, RNA-seq\, ATAC-seq\, DNA methyl-seq and other large-scale epigenomic and chromatin analyses\, including at the single-cell level\, as well as results from high throughput chemical and RNAi/CRISPR phenotypic screens. The work schedule will be between 35-40 hours per week. \n\nPrimary Responsibilities\n\n\n\nPerforms computational analysis and integration of large transcriptomic and epigenetic datasets\nProvides access of public genetic\, epigenetic and transcriptomic large datasets\, for integration with those datasets generated in the lab\nUtilizes existing lab data analysis pipelines\nBuilds new data analysis pipelines\, e.g. for single cell RNA-seq and ATAC-seq.\nManages large dataset storage\, in databases\, lab wiki and lab UCSC browser\nPresents results to lab members at weekly lab meetings\nPresents results and data within SBP\, local La Jolla meetings and national and international meetings\, as appropriate\nMaintains and initiates collaborations between Adams lab and other labs in SBP\, San Diego\, US and worldwide\n\n\n\n\n\nRequired Skills \nRequired Experience \n\n\n\nBachelor’s Degree in Bioinformatics\, Biostatistics\, or Life Sciences or equivalent studies AND a minimum of 5 years work experience OR a Master’s degree in Bioinformatics\, Biostatistics\, or Life Sciences or equivalent studies AND 3 years of work experience in related field OR Ph.D. in Computer Science\, Bioinformatics\, Biostatistics\, or Life Sciences or equivalent studies\, is required\nPh.D. degree in Computer Science\, Bioinformatics\, or Life Sciences or equivalent studies is preferred\nExperience or background in molecular biology or biochemistry is preferred\nExperience with Illumina NGS data analysis is preferred\nPrevious Postdoc training is not required\n\n\n\n\nKnowledge\, Skills\, and Abilities\n\nGeneral familiarity with wet lab assays\nExcellent bioinformatics and programming skills (e.g. Perl\, Python\, C/C++\, Java\, R or Web applications)\nStrong command of Linux/UNIX operating system\nStrong knowledge and skills in bioinformatics\, statistics and next-generation sequencing data analysis\nAbility to use current bioinformatics tools and have an in depth knowledge of advanced sequencing and array-based technologies\nCommunicates effectively and collaborates well with Principal Investigators and their team members\nHave strong organizational and problem-solving skills\nPossesses strong attention to detail\, analytical and time management skills\nExcellent communication and interpersonal skills\nEmbody the Institute’s core values of Commitment\, Collaboration\, Communication\, Community and Compassion
URL:https://ces.b2sg.org/event/8apr19/
LOCATION:Sanford Burnham Prebys Medical Discovery Institute\, 10901 N Torrey Pines Rd\, La Jolla\, CA\, 92037\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20190409
DTEND;VALUE=DATE:20190512
DTSTAMP:20260906T163017
CREATED:20190409T075042Z
LAST-MODIFIED:20190415T121233Z
UID:21192-1554768000-1557619199@ces.b2sg.org
SUMMARY:Associate Scientific Director- Translational Science
DESCRIPTION:As an Associate Scientific Director\, Translational Science working on the Translational Science team\, you will be empowered to establish a collaborative and influential role within Immuno-Oncology Drug Discovery project teams and provides scientific contributions which have significant impact on portfolio progress \, and a typical day will include: \nOBJECTIVES: \nProvides scientific insight from large and diverse biological datasets. Works with a dedicated team of scientists to form data driven decisions\, propose actionable solutions to be tested in the lab or clinic\, and to identify and progress novel cancer therapeutics. Contributes to our mission to provide innovative immuno-oncology therapies to patients across our pipeline of novel therapeutics including small molecule\, large molecule and cell-based therapies. Drives change across the entire drug discovery spectrum from target identification and validation through early clinical proof of concept\, formulating translational hypotheses that inform pharmacodynamic and predictive biomarkers. \nScientific leader with deep subject-matter expertise\, driving project team progression and development of technical capabilities and supporting development of junior team members. \nACCOUNTABILITIES: \n\nApplies computational methods to integrate\, visualize and interpret data resulting from whole genome\, epigenome\, transcriptome\, proteome\, single cell and efficacy studies from preclinical mouse in-vitro\, ex-vivo or in-vivo studies and preclinical human in-vitro and ex-vivo studies.\nEstablishes a collaborative and influential role within Immuno-Oncology Drug Discovery project teams comprised of cell biologists\, biochemists\, pharmacologists and translational scientists. Is responsible for analysis to deduce\, summarize and communicate results directly contributing to the understanding of drug indication\, mechanism of action\, identification of response predictors and translational biomarkers. Works collaboratively with biologists and clinicians to realize clinical benefit from their work.\nWorks collaboratively with data scientists and the information technology group to build knowledgebase solutions within our AWS computational infrastructure capable of performing and communicating genome scale data analysis on abundant proprietary and comprehensive public data\, especially focused on forward and reverse translation challenges.\nPlays a leading scientific role on project team(s)\, setting high standards for rigor of thought\nProvides scientific contributions which have significant impact on portfolio progress or development of technical capabilities\, based on benchmarking to industry best-in-class\nActs as internal key opinion leader for his/her area of technical expertise and serving in a development capacity for junior team members\nSupports or identifies BD opportunities to enhance project progression\, or functional capability expansion\, with clear application to specific portfolio needs\nContinual development of scientific expertise\, particularly through external interactions\, linked to specific deliverables\nContributes to development and implementation of scientific strategy\, through tangible deliverables; challenges dogmas and internal ‘blind spots’; actively pressure-tests ideas cross-functionally and via external network\nEstablishes a strong external reputation\, through scientific publication and presentation\nNote: Job responsibilities are progressive and cumulative\n\nEDUCATION\, EXPERIENCE\, KNOWLEDGE AND SKILLS: \n\nPhD degree in a scientific discipline with 10+ years of experience in computational biology\, or MS with 14+ years of experience in computational biology\, or BS with 16+ years of experience in computational biology\nOutstanding expertise and depth of knowledge within a scientific area\nKeeps up with the up-to-date scientific advancement (e.g. competitive landscape\, new technology\, new research portfolio\, and new partnership)\nDemonstrates well-developed knowledge of other disciplines\, and departments and how they function together. In particular\, the candidate should have extensive experience working closely with biologists or clinicians to influence experimental design.\nThe ideal candidate would have:\n\nExperience with genome scale or big data analysis derived from Next Generation Sequencing including; Exome\, RNA\, miRNA\, Copy Number\, Epigenetics\, Single Cell and synthetic lethal screens\, as well as a track record of using preclinically derived translational hypotheses to influence clinical trial practice.\nData mining\, text mining\, systems biology and visualization solutions including: RStudio\, Shiny\, Omicsoft Array Studio\, Spotfire\, MetaCore\, Ingenuity and MSigDB.\nProgramming\, AWS cloud computing and command line expertise; R\, SQL\, Perl\, Python.
URL:https://ces.b2sg.org/event/9apr19/
LOCATION:Takeda Pharmaceuticals\, 35 Landsdowne St\, Cambridge\, MA\, 02139\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20190415
DTEND;VALUE=DATE:20190518
DTSTAMP:20260906T163017
CREATED:20190415T121010Z
LAST-MODIFIED:20190415T121010Z
UID:21204-1555286400-1558137599@ces.b2sg.org
SUMMARY:Research Technologist
DESCRIPTION:A Research Technologist position is available immediately in Dr. Sinisa Dovat’s lab in the Department of Pediatrics. The focus of our lab research is to study the epigenetic regulation of gene expression in high-risk leukemia and to develop the novel\, targeted therapy for childhood cancer. We are searching for a highly organized and self-motivated individual\, ideally with previous experience in lab management and assisting lab members in individual projects. Conduct experiments including observations\, collect\, compile and process data. Organize data and findings. Analyze data collected. Provide support to the PI\, researchers and technicians both within the lab and collaborating researchers. Order supplies and maintain and organize the inventory. Assist with IACUC and IRB protocols. Train students and others in the lab.  \nSuccessful applicants should have a degree in Biology or related fields. Please upload your CV along with contact information for three references. This job will be filled as a level 1\, or level 2\, depending upon the successful candidate’s competencies\, education\, and experience 
URL:https://ces.b2sg.org/event/penn15apr19/
LOCATION:Penn State\, Old Main\, Hershey\, PA\, 16801\, United States
CATEGORIES:Jobs
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