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PRODID:-//Cancer Epigenetics Society - ECPv5.3.2.1//NONSGML v1.0//EN
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METHOD:PUBLISH
X-WR-CALNAME:Cancer Epigenetics Society
X-ORIGINAL-URL:https://ces.b2sg.org
X-WR-CALDESC:Events for Cancer Epigenetics Society
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TZID:Europe/Paris
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TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:CEST
DTSTART:20190331T010000
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TZOFFSETTO:+0100
TZNAME:CET
DTSTART:20191027T010000
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20190602
DTEND;VALUE=DATE:20190810
DTSTAMP:20260909T180641
CREATED:20190602T105658Z
LAST-MODIFIED:20190602T105841Z
UID:21284-1559433600-1565395199@ces.b2sg.org
SUMMARY:Postdoctoral Fellow
DESCRIPTION:The new R&D Oncology organisation brings together early and late oncology teams\, from discovery through to late-stage development\, with oncology specific Regulatory and Biometrics groups. \nYou’ll be in a global pharmaceutical environment but also exposed to strong rigorous academic science. For example\, every postdoc has an external academic mentor to ensure we are working and publishing at the highest level in a field. What’s more\, you’ll have the support of a leading academic advisor\, who’ll provide you with the guidance and knowledge you need to develop your career. \nYou’ll be associated with a project aligned with our scientific platform of Tumour Driver and Resistance\, aiming to elucidate the mechanism of an epigenetic protein that functions as a resistance mechanism for cancer and define the combination strategy to overcome the drug resistance. \nEducation and Experience required: \nEssential: \n\nPhD in oncology\, cell biology\, or related field\nStrong desire to learn and perform cancer research in an industry setting\nExpertise in epigenetic oncology and/or RTK signalling pathways\nStrong scientific background in mechanisms of disease and drug resistance.\nExperience with a variety of laboratory\, molecular\, and cellular biology techniques  \n\nDesirable: \n\nRelevant bioinformatic experience\n\nSkills and Capabilities required: \n\nHighly motivated\, innovative and reliable with the ability to effectively problem solve\nFlexible\, collaborative and team-oriented mind set\nStrong publication track record\nExcellent communication skills (oral and written)\n\nThis is a 3-year programme.  2 years will be a Fixed Term Contract\, with a 1-year extension which will be merit based.  The role will be based in Waltham\, MA\, USA\, with a competitive salary on offer. To apply for this position\, please click the apply link below.
URL:https://ces.b2sg.org/event/az-2jun19/
LOCATION:AstraZeneca\, Gaithersburg\, MD\, 20878\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20190624
DTEND;VALUE=DATE:20190727
DTSTAMP:20260909T180641
CREATED:20190624T160525Z
LAST-MODIFIED:20190624T160525Z
UID:21308-1561334400-1564185599@ces.b2sg.org
SUMMARY:Research Technician
DESCRIPTION:Dr. Hari’s laboratory at Huntsman Cancer Institute and College of Pharmacy under Therapeutics Accelerator program is seeking a highly motivated Research Technician with expertise in conducting various in vitro cancer biology and drug screening assay for the kinase\, epigenetic and immune related protein targets. Interested candidate will be working on the biological evaluation of novel chemical entities (NCE) for use in cancers research and treatment. Research Technician\, you will be technically responsible for working on the PI and his labs chemist fellows to support in vitro cell-free and cancer cell-based efficacy screening assays utilizing available compounds as and when made by chemist fellows. This will entail detailed reading of the literature reported assays\, validation using reference control compounds\, associated methods\, existing assay protocols\, and alos utilizing vendor specific reagents/kits etc.\, and then planning\, execution\, optimization and analysis of the assay results. The compound effects in those assays and presenting the results in group meetings\, then supporting sections of grant proposals\, publications\, and lab supervision. \n\nResponsibilities \n\nCell-free target binding assays; kinase glo\, thermal shift and FP\, FRET\, AlphaScreen\, AlphaLisa\,\nIC50\, EC50\, Ki\, Kd\, Km\, substrate competitive\, reversibility and time dependent read out data analysis and handling expertise\nCell-based\, cancer cellular profiling and synergy experiments handling expertise are part of the job description\nAdditional experience in cancer biology investigations such as conducting standard biochemical/binding or other relevant target specific mechanistic assays such as Flow Cytometry\, NK\, B cell\, immune cell killing\, cytokine release\, Macrophage\, other immunoassays and working experience on radioligand binding assays is a plus.\nAbility to clearly communicate ideas verbally and through presentations.\n\nMinimum Qualifications \nBachelor’s degree in biology\, chemistry\, or other scientific disciplines in a related field or equivalency required; knowledge of complex laboratory techniques\, equipment\, terminology\, materials and substances. Skilled in the use of laboratory equipment\, ability to create and analyze statistical calculations and prepare reports required; and demonstrated human relations and effective communication skills also required. OSHA training and certification in animal care and use or the willingness to complete the certification may be required by some departments. \nApplicants must demonstrate the potential ability to perform the essential functions of the job as outlined in the position description.
URL:https://ces.b2sg.org/event/ut-24jun19/
LOCATION:University of Utah\, 201 Presidents Cir\, Salt Lake City\, 84112\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20190624
DTEND;VALUE=DATE:20190727
DTSTAMP:20260909T180641
CREATED:20190624T161941Z
LAST-MODIFIED:20190624T161941Z
UID:21310-1561334400-1564185599@ces.b2sg.org
SUMMARY:Research Specialist
DESCRIPTION:The Department of Nutritional Sciences at The University of Arizona leads in cutting-edge Research\, outstanding Undergraduate and Graduate Programs\, Cooperative Extension Programs and Continuing Professional Education that advance the discovery and translation of the roles of nutrition and physical activity in optimizing health and wellness for people in Arizona and beyond. The Department of Nutritional Sciences announces the availability of a Research Specialist position under the supervision of Dr. (Ski) Floyd H. Chilton.\nThese position’s duties include performing a wide variety of standard laboratory experimental procedures\, analyzing data\, assisting with writing will manuscripts for publication\, and possibly leading and coordinating the work of other staff.\nThe successful candidates will possess resourcefulness and adaptability in order to address the special and changing needs of research in one specialized field. They will also have the ability to modify and adapt standard procedures to meet the needs of the project while performing preliminary analysis. These positions may require work with potentially hazardous materials such as toxic chemicals\, radiation and/or disease-causing organisms. \nDr. Chilton’s research focuses on how genetic and epigenetic variations interact with human diets (especially the modern Western diet) to drive inflammation and inflammatory disorders (including cardiovascular disease and cancer)\, as well as psychiatric/developmental disorders (ADHD\, autism spectrum disorder\, and depression). \nFunding for these positions is contingent on research grants and will be renewed annually. The individual will be expected to work collaboratively with Dr. Chilton to support research carried out in his laboratory and with his collaborators at the University of Arizona\, University of Arizona Health Sciences\, and affiliated institutions\, including Wake Forest School of Medicine\, Johns Hopkins School of Medicine\, and the University of Virginia.
URL:https://ces.b2sg.org/event/az-24jun19/
LOCATION:University of Arizona\, Tuscon\, AZ\, 85721\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20190624
DTEND;VALUE=DATE:20190727
DTSTAMP:20260909T180641
CREATED:20190624T163706Z
LAST-MODIFIED:20190624T163706Z
UID:21312-1561334400-1564185599@ces.b2sg.org
SUMMARY:Post Doctoral Scientist
DESCRIPTION:We are seeking a Post-Doctoral Scientist –  Multiple Postdoctoral Fellow Positions in Epigenetics\, human iPS cells\, 3D Bioprinting\, Hematopoietic Stem Cell Biology\, Bioengineering\, and Blood Cancers: Columbus\, OH\, United States. \n   \nThe Shah laboratory provides a dynamic microenvironment that offers excellent opportunities for intellectual exchange and collaborations among investigators from diverse fields. We investigate the origin\, development\, and differentiation of hematopoietic stem cells (HSCs)\, and their utility in treating patients with blood and bone marrow diseases. \n\nWe have expertise in utilizing zebrafish\, mice\, and human induced pluripotent stem (iPS) cells to analyze novel genes and mechanisms important for blood formation. Our goals are to utilize our knowledge in developing cellular- and mechanism-based therapies as well as generating functional HSCs for the treatment of hematological diseases. \n\n\n\n\n\n\n  \n\n\n\nQualifications\n\n\n\nWhat Are We Looking For? \n\nPosition # 1: Epigenetics of Hematopoietic Stem Cell Development and Disorders. \nThe ideal candidate will have Ph.D.\, M.D.\, or M.D./Ph.D. in Regenerative Medicine\, Stem Cells\, Immunotherapy\, Hematology\, Oncology\, and/or Biology. This position offers an excellent opportunity to learn and apply skills in epigenetics\, directed differentiation of human induced pluripotent stem cells (iPSCs)\, HSC transplant\, xenograft\, computational biology\, high-throughput screening\, gene-editing\, and/or molecular and cellular biology techniques. \n\n\nMinimum Physical Requirements: \n  \n\nSitting Constantly (67-100%)\nTalking on phone/in person constantly (67-100%)\nTyping on a keyboard occasionally (0-33%)\nStanding/walking occasionally (0-33%)\n\n\nThe above list of duties is intended to describe the general nature and level of work performed by individuals assigned to this classification. It is not to be construed as an exhaustive list of duties performed by the individual so classified\, nor is it intended to limit or modify the right of any supervisor to assign\, direct\, and control the work of employees under his/her supervision.
URL:https://ces.b2sg.org/event/nc-24jun19/
LOCATION:Nationwide Children’s Hospital Research Institute\, 700 Children's Dr\, Columbus\, OH\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20190625
DTEND;VALUE=DATE:20190728
DTSTAMP:20260909T180641
CREATED:20190625T133214Z
LAST-MODIFIED:20190625T133214Z
UID:21314-1561420800-1564271999@ces.b2sg.org
SUMMARY:Faculty Position
DESCRIPTION:The Department of Urology and the Robert H. Lurie Comprehensive Cancer Center at Northwestern University Feinberg School of Medicine are leading the search for a full-time tenure track Investigator up to the rank Professor in the area of prostate cancer biology. \nQualified candidates will have a PhD or MD or dual degree and an outstanding record of research in prostate cancer biology. The successful applicant will have experience in the field of cancer biology\, which could include cancer genetics and proteomics\, cancer cell biology\, tumor microenvironment\, cancer stem cells\, metastasis\, tumor immunology\, chemical biology\, cancer metabolism\, oncogenic signal transduction pathways\, genome integrity\, and cancer epigenetics.  We are seeking an individual with an established program in prostate cancer who is drawn to the broad opportunities at Northwestern with its collaborative clinical programs at Northwestern Memorial Hospital. The Center for Genetic Medicine houses the NUgene biobank and the Robert H. Lurie Comprehensive Cancer Center offers a robust research infrastructure for translation. \nThe start date is negotiable and the position will remain open until filled. When applying\, please upload this completed list of references form to suggest the names of individuals who could write letters of reference on your behalf.  \nPlease read ALL instructions and make preparations before proceeding to the application page: \n\nApplications will only be accepted via online submission (see link below).\nPlease prepare all documents in advance as Adobe PDF files\, and please be sure all information is entered correctly and accurately (especially names and email addresses)\, as there will be no opportunity for online revision after your application has been submitted.\nAll required fields in the application form are marked with an asterisk and must be filled before clicking the “Submit” button.\nBe aware that incomplete applications cannot be saved.\n\nApplications accepted here: Apply for Job
URL:https://ces.b2sg.org/event/nwu-25jun19/
LOCATION:Northwestern University\, 633 Clark St\, Evanston\, IL\, 60208\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20190626
DTEND;VALUE=DATE:20190729
DTSTAMP:20260909T180641
CREATED:20190626T161757Z
LAST-MODIFIED:20190626T161757Z
UID:21316-1561507200-1564358399@ces.b2sg.org
SUMMARY:Lab Assistant I
DESCRIPTION:The proposed position will be located at the Dermatology Research labs\, specifically in the DiNardo Lab. The dermatology labs are located at the Altman Clinical and Translational Research Institute (ACTRI) at UC San Diego\, established in 2010 as part of a national consortium of 60 medical research institutions created to energize bench-to-bedside efforts. The structure was opened in 2016 and encompasses 359\,000 square feet of offices\, state-of-the-art laboratories and clinical space (including a research pharmacy) and houses a multitude of distinct research endeavors as described before. \nThe Lab Assistant will engage in assisting postdoctoral fellow and senior scientists working on skin innate immune projects related to microbiome and immune-tolerance. Under supervision\, the lab assistant will assist with preparation and execution of experiments using biological and chemical materials. Tasks will include preparation of standardized media and reagents; upkeep of laboratory apparatus and facilities; ordering and organization of laboratory supplies; record-keeping and organization of experimental outputs on the laboratory computer notebook and databases. \nThe assistant will have an opportunity to observe and aid senior laboratory members with experiments involving cell culture\, PCR\, specimen sectioning\, molecular cloning\, genotyping and gel electrophoresis. \nMINIMUM QUALIFICATIONS\n\nGraduation from high school or a GED and one (1) year of laboratory experience or two (2) years of college including courses in the biological sciences; or an equivalent combination of education and experience.\nPossess the knowledge and abilities essential to the successful performance of the duties assigned to the position.\nProven experience doing standard and routine laboratory tasks. Skill to accurately organize\, store\, and retrieve samples\, chemicals\, and supplies.\nSolid organizational skills to order and maintain lab reagents and supplies\, and keep accurate lab records and computer files using Excel.\nDemonstrated ability to follow written and verbal protocols\, techniques\, and instructions.\nWillingness to work with small animals (mice) and to assist in procedures in compliance with standards and protections (ACP and IACUC).\nStrong experience making decisions\, analyzing situations\, problem solving\, and initiating action for laboratory maintenance.\nAbility to read\, comprehend\, discuss\, and present research materials.\nWillingness to convey skin specimens between nearby facilities (short walking distance).\nWillingness to learn new theory\, techniques\, and tasks and share knowledge.\n\nPREFERRED QUALIFICATIONS\nA Bachelor’s Degree in Biological Science discipline.
URL:https://ces.b2sg.org/event/ucsd-26jun19/
LOCATION:UC San Diego Health – Moores Cancer Center\, 3855 Health Sciences Drive\, La Jolla\, CA\, 92037\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20190702
DTEND;VALUE=DATE:20190805
DTSTAMP:20260909T180641
CREATED:20190702T170150Z
LAST-MODIFIED:20190702T170418Z
UID:21319-1562025600-1564963199@ces.b2sg.org
SUMMARY:Research Opportunities - Medical Oncology
DESCRIPTION:There is an opportunity for research in the laboratory of Dr. Jieya Shao. The central theme of the lab is unravelling novel cancer biology with the overarching goal of developing effective therapies. Two main projects are currently ongoing primarily in the context of breast cancer: \n1. “Moonlighting” functions of the actin-binding protein profilin-1 (Pfn1) in transcriptional and epigenetic regulation. As an essential eukaryotic protein\, the mechanisms behind the paradoxical anticancer effects of profilin-1 have remained mysterious for nearly two decades. Our recent studies suggest that the anticancer activities of Pfn1 may stem from its poorly understood nuclear functions which become deregulated in cancer due to an alteration of its nucleocytoplasmic trafficking. We are currently focusing on defining its novel roles in transcriptional control and epigenetic regulation in the context of both estrogen receptor positive and triple negative breast cancer by utilizing multidisciplinary approaches including biochemistry\, molecular and cellular biology\, proteomics\, mouse xenograft models\, and next generation sequencing.\n2. The role of VCP in protein homeostasis\, DNA damage response\, and chemotherapy efficacy of cancer. Valosin-containing protein (VCP) is an evolutionarily conserved and highly abundant AAA+ ATPase involved in diverse cellular processes. Functioning as a “segregase”\, VCP maintains protein homeostasis by extracting polyubiquitinated proteins from various cellular locations or complexes for turnover. Numerous studies have now linked VCP to chromatin-associated protein degradation and genome stability maintenance particularly in the context of DNA damage response. Nevertheless\, detailed understanding of its mechanism of action\, its mode of (de)regulation in cancer\, and its relevance to chemotherapy response is lacking\, and we are currently investigating all these questions. \n\n\nPreferred Qualifications\n\n\n\n\n\n\n\n\nCandidates with general understanding of biochemistry\, molecular and cellular biology and prior experience in mammalian cell culture\, Western blotting\, DNA/RNA isolation\, mouse handling and surgery are preferred.\nKnowledge in genetics/epigenetics and experience in quantitative PCR and chromatin immunoprecipitation (ChIP) is a plus\, so is the skill in data mining and computational analysis.\nMust have troubleshooting skills\, independent analytical thinking and research planning skills.\nDemonstrated ability to work independently and communicate with the laboratory staff and investigators.\nAbility to maintain complete and organized records/reports.\nWorking knowledge of computer software and general lab equipment.
URL:https://ces.b2sg.org/event/2jul19/
LOCATION:Washington University in St. Louis\, 1 Brookings Dr.\, St. Louis\, MO\, 63130\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20190720
DTEND;VALUE=DATE:20190722
DTSTAMP:20260909T180641
CREATED:20190414T094212Z
LAST-MODIFIED:20190414T094413Z
UID:21200-1563580800-1563753599@ces.b2sg.org
SUMMARY:Dynamics of Epigenetic Regulation: Mechanisms and Beyond
DESCRIPTION:The Gordon Research Seminar on Epigenetics is a unique forum for graduate students\, postdocs\, and other junior scientists to present and exchange new data and cutting-edge ideas. The focus of this meeting is on recent advances in our understanding of the dynamic nature of epigenetic regulatory mechanisms across phyla. In particular\, we will focus on how epigenetic alterations can influence phenotypic plasticity\, development\, reprogramming\, and transgenerational inheritance. The GRS will include a keynote address by Dr. Bradley Cairns\, as well as a career panel discussion with panelists from academic and non-academic fields. \nApplication Instructions\nThe seminar will feature approximately 10 talks and 2 poster sessions. All attendees are expected to actively participate in the GRS\, either by giving an oral presentation or presenting a poster. Therefore\, all applications must include an abstract. \nThe seminar chair will select speakers from abstracts submitted by April 20\, 2019. Those applicants who are not chosen for talks and those who apply after the deadline to be considered for an oral presentation will be expected to present a poster. In order to participate\, you must submit an application by the date indicated in the Application Information section above. \nProgram Format\nGordon Research Seminars are 2-day meetings which take place on the Saturday and Sunday just prior to the start of the associated GRC. The GRS opens with a 1-hour introductory session on Saturday afternoon\, followed by a poster session\, dinner and a 2-hour session in the evening. Sunday morning begins with breakfast and is followed by another 2-hour session\, a second poster session\, and lunch. A final 1-hour session takes place just after lunch\, and the associated GRC begins later that evening. \nAn outline of the program components for this GRS is displayed below. The seminar chair is currently developing their detailed program schedule\, which will include the speakers they select from submitted abstracts\, in addition to any additional components outlined below. The detailed program will be available by May 20\, 2019. Please check back for updates. \n\nKeynote Speaker\n\n\n\nBradley Cairns (University of Utah\, USA)\n\n\n\nSpeakers\n\n\n\nTo Be Selected from Submitted Abstracts\n\n\n\nDiscussion Leaders\n\n\n\nJulie Ahringer (University of Cambridge\, United Kingdom)\nAmander Clark (University of California\, Los Angeles\, USA)\n\n\n\n\nAdditional Discussion Leaders May Be Selected from Submitted Abstracts\n\n  \nApplications for this meeting must be submitted by June 22\, 2019. Please apply early\, as some meetings become oversubscribed (full) before this deadline. If the meeting is oversubscribed\, it will be stated here. Note: Applications for oversubscribed meetings will only be considered by the conference chair if more seats become available due to cancellations. \nGRS Speaker Abstract Deadline: Although applications will be accepted until the date noted above\, any applicants who wish to be considered for an oral presentation should submit their application by April 20\, 2019. Please refer to the application instructions in the Conference Description section below for more details (if available).
URL:https://ces.b2sg.org/event/grs-meeting20jul19/
LOCATION:Holderness School\, 33 Chapel Ln\, Holderness\, NH\, 03245\, United States
CATEGORIES:Meetings
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