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X-WR-CALDESC:Events for Cancer Epigenetics Society
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DTSTART;VALUE=DATE:20180815
DTEND;VALUE=DATE:20180917
DTSTAMP:20180815T112224Z
CREATED:20180815T112224Z
LAST-MODIFIED:20180815T112224Z
UID:20469-1534291200-1537142399@ces.b2sg.org
SUMMARY:Research Scientist - Leukemia
DESCRIPTION:Dr. Kapil N. Bhalla is currently seeking a Senior Research Scientist who will be responsible for conducting research in his NIH-funded laboratory. The focus of the basic and translational research in this laboratory includes the biology and developmental therapeutics related to epigenetic mechanisms involving histone deacetylases\, methyltransferases and demethylases\, BET proteins\, as well as the chaperone biology of heat shock proteins and their cancer relevant client proteins regulating cell growth\, differentiation and survival of the human leukemia stem/progenitor cells. The qualified candidate must possess a Ph.D. in Biology\, Biological Sciences\, Life Sciences or related field and a keen interest and experience in cancer research. The candidate must have completed at least a 3 year Post-doctoral fellowship in an area relevant to the focus of research in Dr. Bhalla’s laboratory. The qualified candidate must have the ability to troubleshoot in the design and conduct of the laboratory studies. Experience in molecular studies involving gene transfection\, analysis of gene expression through QPCR\, microarrays\, immunoblots and flow cytometry\, as well as experience in chromatin immunoprecipitation studies\, evaluation of protein biochemistry with 2D gels and the yeast-two-hybrid system\, and tissue culture techniques is required. Experience in the ability to utilize CRISPR technology for gene editing and to utilize confocal microscopy for molecular imaging is highly desired. Experience in xenograft and genetically-engineered animal models of cancer and/or leukemia\, and confocal microscopy is also desired. An outstanding research environment\, new laboratory and core facilities are provided.  \nThe salary range is: min-$53\,200\, mid-$66\,500 and max-$79\,800.  \nKEY FUNCTIONS  \nResearch Design and implementation  \nPlans\, organizes\, coordinates\, directs and conducts scientific research projects. Develops and maintains standard procedures and protocols to ensure the quality and integrity of the procedures performed. Coordinates with other investigators to provide appropriate support on analytical techniques. Maintains detailed experimental records\, evaluates resulting research data\, and presents findings to physicians and/or professional groups.  \nData Analysis  \nAnalyzes and evaluates research data and revises techniques and approaches to work problems. Works with the Principal Investigator on projects in the area of biomarker development and leukemia biology. Participates in adopting new techniques and learning new skills to enhance research efforts.  \nLab Development/Publications  \nSupervises\, mentors\, and counsels trainees and other laboratory personnel with respect to proper laboratory techniques\, the use of laboratory equipment and safety procedures. Publications/Manuscripts and Presentations. Contributes to manuscripts and prepares documents for publication. Compiles\, writes\, and submits reports to superior. Presents results at national meetings.  \nOther duties as assigned.  \nEDUCATION  \nRequired: PhD in one of the natural sciences or related field or Medical degree.  \nEXPERIENCE  \nRequired: With PhD\, no experience required. With Medical degree\, two years of experience in experimental or scientific work. 
URL:https://ces.b2sg.org/event/mda-15aug18/
LOCATION:MD Anderson Cancer Center\, 1515 Holcombe Blvd\, Houston\, TX\, 77030\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180813
DTEND;VALUE=DATE:20180915
DTSTAMP:20180813T120800Z
CREATED:20180813T120800Z
LAST-MODIFIED:20180813T120800Z
UID:20465-1534118400-1536969599@ces.b2sg.org
SUMMARY:Program Co-Leader - Cancer Molecular Genetics
DESCRIPTION:The Program Co-Leader\, Cancer Molecular Genetics is responsible for the oversight\, development\, implementation and evaluation of the cancer molecular genetics related programs and initiatives at Massey Cancer Center. \n\n\n\n\nPosition Responsibilities\n\nThe Virginia Commonwealth University (VCU) School of Medicine and Massey Cancer Center are seeking a successful scientist and leader to serve as the Program Co-Leader of the Cancer Molecular Genetics (CMG) research program at the cancer center. The CMG program consists of a multidisciplinary group of 26 investigators from 12 academic departments representing four schools. This tenure-eligible faculty position will be a key member of Massey’s leadership team. \nResponsibilities \n\nProvide oversight\, development\, implementation and evaluation of cancer molecular genetics related programs and initiatives at Massey Cancer Center\nPartner with the Director\, Associate Directors and other Program Leaders at Massey to enhance the cancer center’s scientific goals and objectives\nWork closely with leadership to encourage and facilitate multidisciplinary collaboration and translational research at the cancer center\nConduct fundamental research that can be translated into improved approaches for diagnosis\, prevention\, and treatment of neoplastic diseases\n\n\nResearch can include but not limited to the following areas: \n\nEpigenetic mechanisms in cancer development and progression: Understanding the regulation and interaction of histone modifications and other epigenetic controls including DNA methylation and miRNA; recognition of these post-translational modifications in DNA-chromatin complexes by nucleosome remodeling factors\, and the role of miRNA in these processes\nDefinition of the functional significance of genes involved in cancer development and progression\, and exploiting this information to identify and validate promising targets\nDefinition of the pathways that delete and silence tumor suppressor genes in human cancers\n\n\n\n\n\n\nRequired Qualifications\n\n\nPhD or MD/PhD\nArea of cancer research expertise in epigenetics or epigenomics\nSolid track record of scientific achievement reflected by both sustained and recent impactful publications and extramural peer-reviewed research funding in cancer related research as a Principal Investigator\n\n\n\n\n\nPreferred Qualifications\n\n\nProven leadership\, relationship building\, and strong communication skills\nExperience working in a matrix environment within academic medicine\nProven success in collaborating with multi-disciplinary teams\nDemonstrated experience working with and fostering diverse faculty\, staff\, and student environment or commitment to do so as a faculty member at VCU
URL:https://ces.b2sg.org/event/vcu-13aug18/
LOCATION:Virginia Commonwealth University\, 907 Floyd Ave\, Richmond\, VA\, 23284\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/09/VCU-virginia-commonwealth-e1506279590219.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180812
DTEND;VALUE=DATE:20180929
DTSTAMP:20180812T160400Z
CREATED:20180812T160400Z
LAST-MODIFIED:20180812T160400Z
UID:20463-1534032000-1538179199@ces.b2sg.org
SUMMARY:Faculty Position in Cancer Biology/Genetics
DESCRIPTION:The Life Sciences Institute (LSI) at the University of Michigan invites applications for an open rank faculty position in Cancer Biology/Genetics. Successful candidates will have experience in cancer biology/genetics\, with specific research targets related to cancer metabolism\, cancer genetics/genomics/epigenetics\, chemical biology\, tumor microenvironment\, or tumor immunology. \nFaculty will hold both a Research Professor appointment in the LSI as well as an Assistant\, Associate\, or Full Professor appointment in one of the University’s schools and colleges. Joint appointments are likely in the Medical School\, the College of Literature\, Science\, and the Arts\, the College of Engineering\, the School of Public Health\, the Dental School\, or the College of Pharmacy. All faculty are expected to participate in the University of Michigan’s teaching mission and to demonstrate commitment to service in the larger community. Candidates are expected to develop an internationally recognized program of scholarly research and to excel in teaching and mentoring at the graduate level. \nThe LSI is a scientific enterprise at the University of Michigan dedicated to fundamental discovery in the biological sciences in a state-of-the-art collaborative physical space (www.lsi.umich.edu). Through basic discovery\, the institute seeks to advance knowledge in critical areas of biology with an ultimate goal of contributing to human health including cancer\, metabolic disorders\, brain disorders\, and infectious disease. \nThe LSI is currently home to 22 faculty members in the disciplines of chemistry\, cell biology\, physiology\, genetics\, chemical biology\, biophysics\, structural biology\, and stem cell biology\, including three Howard Hughes Medical Institute investigators and eight members of the National Academies of Medicine or Sciences. Our culture centers on upholding scientific excellence\, embracing risk\, and collaborating across disciplines to achieve an impact greater than the sum of our individual parts. \nIn addition to faculty labs\, the institute houses state-of-the-art instrumentation and computing\, including the following transmission electron microscopes: 300kV Titan Krios\, 200kV Talos Artica\, 120kV Tecnai G2 Spirit\, and 100vK Morgagni. Additional institute resources include high-throughput screening center with extensive chemical collections and a unique library of natural product extracts\, and a comprehensive protein production and X-ray crystallography facility. The LSI is also home to the U-M Program in Chemical Biology. \nApplication materials are due on Friday\, September 28\, 2018. Interested applicants will submit a cover letter\, curriculum vitae\, a summary of future research plans (up to 4 pages)\, contact information for three faculty who will write a letter of recommendation\, and copies of up to three publications on our online application site (lsi.science/2018facultyposting). Individuals from groups historically under-represented in the sciences are strongly encouraged to apply.
URL:https://ces.b2sg.org/event/mi-12aug18/
LOCATION:University of Michigan\, 500 S State St\, Ann Arbor\, MI\, 48109\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/05/uni-michigan.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180811
DTEND;VALUE=DATE:20180913
DTSTAMP:20180811T162945Z
CREATED:20180811T162945Z
LAST-MODIFIED:20180811T162945Z
UID:20461-1533945600-1536796799@ces.b2sg.org
SUMMARY:Postdoctoral Positions in Translational Leukemia Research
DESCRIPTION:The Translational Leukemia Research Program at the Perlmutter Cancer Center and New York University (NYU) School of Medicine invites post-doctoral applications in the laboratory of Dr. Raoul Tibes\, the Director of Leukemia Program. The focus of the Laboratory is the molecular-genomic characterization of primary acute myeloid leukemia (AML)\, myelodysplastic syndrome (MDS) and myeloproliferative neoplasm (MPNs) in correlation of their response to current therapies and novel investigational agents\, and understanding the mechanisms of drug resistance. The Tibes laboratory has been instrumental in providing pre-clinical data based on functional genomic information for several novel treatments (i.e. epigenetic and apoptosis targeting combinations) that are currently in clinical trials for AML\, MDS and MPNs. The Tibes laboratory is highly collaborative and the successful candidate will work with leading academic clinicians and basic scientists at NYU\, other academic Cancer Centers\, and pharmaceutical companies to discover and delineate the clinical path for novel therapeutic agents. The laboratory publishes in high-impact journals and former members of the laboratory hold positions at academic institutions or biotech and pharmaceutical companies. \nCurrently available projects include: understanding the mechanisms of the anti-leukemic activity DNA damage repair interference by WEE1 and CHEK1 inhibition; characterizing epigenetic/hypomethylating agent resistance and the design of rational hypomethylating agent based combinations in AML and MDS; as well as novel therapeutic approaches for MPNs. \nThe successful candidate will have strong dedication and independence\, effectively communicate their work by publishing the results in premier journals and will be involved in grant writing with an opportunity to submit their own career awards. The applicant and projects will benefit from a scientifically stimulating environment\, with extensive resources and opportunities to collaborate within NYU and externally. There is close interaction with the PI and candidates will be actively involved in various aspects of translational cancer research and drug development. The Lab is funded by several agencies including the NCI\, LLS and ASCO and at the institutional level. \nIn addition to world-class research facilities and to opportunities within the Lab and Cancer Center\, NYU Langone Health and NYU School of Medicine has a robust career development program led by our Office of Postdoctoral Affairs. One of only 17 schools to receive an NIH BEST (Broadening Experiences in Scientific Training)\, the Office of Postdoctoral Affairs offers over 30 courses and workshops on career planning\, communication skills\, negotiating\, and conflict management\, as well as career-specific training for careers in academia\, pharma/biotech\, science policy\, medical communications\, and many more. Additional information can be found at www.med.nyu.edu/postdoc \nRequirements: Applicants should have a Ph.D. degree (or equivalent) in molecular biology\, cancer biology\, or relevant fields. Applicant must be able to work independently in a fast-paced\, dynamic research environment. \nApplication process: Interested applicants should send a letter of motivation\, a curriculum vitae\, and the contact information of 3 references as a single combined pdf file (subject line post-doctoral application) to raoul.tibes@nyumc.org.
URL:https://ces.b2sg.org/event/nyu-11aug18/
LOCATION:NYU School of Medicine\, 550 1st Avenue\, New York\, NY\, 10016\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180810
DTEND;VALUE=DATE:20180912
DTSTAMP:20180810T205107Z
CREATED:20180810T204703Z
LAST-MODIFIED:20180810T205107Z
UID:20459-1533859200-1536710399@ces.b2sg.org
SUMMARY:Senior Scientific Researcher
DESCRIPTION:We are seeking a Senior Scientific Researcher in the Department of Molecular Biology to support the production and optimization of genetically-modified cellular models. This position will be within the newly-established Cell Engineering Lab\, wherein she/he will facilitate the design\, execution\, and validation of cell line engineering projects initiated by researchers across Genentech — with the ultimate goal of generating more effective in vitro/ex vivo disease models and novel contexts for functional genomic screening. The candidate is expected to work creatively and independently within an extremely dynamic\, collaborative research environment. \nA self-motivated candidate with a PhD in Genetics\, Molecular Biology\, Biochemistry\, Cancer Biology\, or a related discipline. Qualified candidates will have a skillset demonstrating successful\, documented application of molecular genetics/genome engineering either in cell-based systems or model organisms. Preferred expertise includes some or all of the following: DNA nucleases\, 2D and 3D cell culture\, RNA interference (siRNA/shRNA)\, reporter gene assays\, primary and/or stem cell models\, molecular cloning\, RNA/DNA/protein quantification\, epigenetics\, and viral vector development/use. Working knowledge of pooled vector-based screening\, Next-Gen Sequencing (NGS)\, biostatistics\, and/or basic bioinformatics is desirable. The successful candidate will be team-oriented\, highly organized\, and have excellent communication skills\, both written and verbal.
URL:https://ces.b2sg.org/event/genentech-10aug17/
LOCATION:Genentech\, 1 DNA Way\, South San Francisco\, CA\, 94080\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/05/genentech-logo.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180808
DTEND;VALUE=DATE:20180910
DTSTAMP:20180808T074415Z
CREATED:20180808T074415Z
LAST-MODIFIED:20180808T074415Z
UID:20457-1533686400-1536537599@ces.b2sg.org
SUMMARY:Bioinformatics Analyst
DESCRIPTION:The Van Andel Research Institute has a position available for one Bioinformatics Analyst under the shared direction of Peter W. Laird\, Ph.D and/or Hui Shen\, Ph.D. Depending on the interests and expertise of the successful candidate\, the position can be a sole appointment in either the Laird or Shen laboratory\, or a joint appointment between the two labs. \nThe Laird Laboratory focuses on the role of epigenetics in cancer\, combining mechanistic studies in model systems\, analysis of human cancer tissues\, advanced technology development\, and epigenomic data analysis. \nThe Shen Laboratory focuses on the epigenome and its interaction with the genome in various diseases\, with a specific emphasis on female cancers and cross-cancer comparisons relying on innovative computational tool development and epigenomic data analysis. \nAs a Bioinformatics Analyst on our team\, your first and foremost responsibility will be to work closely with lab members on the analysis of next-generation sequencing data. Additional responsibilities might include: \n\nMaintain and support bioinformatics software.\nAssist research faculty in data mining of publicly available data sets.\nAnalyze data through established workflows and pipelines.\nEngage in bioinformatics literature to ensure the availability of robust methods\, resources\, and data sources to support core users.\nMaking figures for manuscripts\nDirect and guide DNA\, RNA and protein sequence database searches and the computational analysis of resulting data.\nMaintain computational infrastructure and control the flow of samples and information for large-scale studies.\nRecognize and report problems with the data management process and fix problems whenever possible.\n\n\nThis position is available immediately for a motivated scientist who meets the qualifications and description outlined below. \nQualifications: \n\nBachelor’s degree in bioinformatics\, computational and systems biology\, mathematical\, physical\, or computer science with a Master of Science (MS) preferred. 2+ years of experience in computer programming and computational biological applications.\nExperience in such functional areas as image analysis\, NGS data analysis\, and data integration. Understanding of cellular and molecular biology and/or genetics is a plus.\n1-3 years of experience in a scripting language (Python\, Perl\, etc.). A working knowledge of R is expected. Working knowledge of public biological databases (NCBI\, ENCODE\, ENSEMBL\, UCSC\, etc.).\nContributions to the broader bioinformatics community through software and methods development.\nMust provide the names of three individuals who can provide recommendations and present a scientific seminar describing his or her previous research.\n\n\nDescription of a Successful Candidate: \n\nA “team” focused scientist\nA self-motivated and driven individual who is able to exhibit exceptional research productivity and take responsibility for independent management of the project\nA detail-oriented researcher who thinks critically to effectively design experiments and solve complex research problems\nA strong ability to take initiative and work independently\nA collaborative\, hands-on researcher who proactively shares knowledge and expertise with lab members and has an interest in helping junior lab members\nExcellent written and oral communication skills\n\n\nHOW TO APPLY \nIf you possess these attributes and enjoy working with motivated and driven people\, we would welcome speaking with you and encourage you to apply today! \n\nA cover letter describing your research interests\, experience\, and how you might contribute to Laird Lab Research.\nAn up-to-date Curriculum Vitae.\nA list of 3 individuals who have agreed to act as references along with their contact details.\n\nPlease contact Eric Miller (eric.miller@vai.org) for further information or questions\, or if you have any difficulty with the application process.
URL:https://ces.b2sg.org/event/vari-7aug18/
LOCATION:Van Adel Research Institute\, Grand Rapids\, MI\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180805
DTEND;VALUE=DATE:20180907
DTSTAMP:20180805T061116Z
CREATED:20180805T061116Z
LAST-MODIFIED:20180805T061116Z
UID:20455-1533427200-1536278399@ces.b2sg.org
SUMMARY:Postdoctoral Fellow
DESCRIPTION:The Van Andel Research Institute has a position available for one Postdoctoral Fellow under the direction of Peter W. Laird\, Ph.D. \nThe Laird Laboratory focuses on the role of epigenetics in cancer\, combining mechanistic studies in model systems\, analysis of human cancer tissues\, advanced technology development\, and epigenomic data analysis. \nA major focus of this position will be to investigate cellular epigenetic heterogeneity as a predeterminant of malignant transformation potential using single cell epigenomics in mouse models. \nThis postdoctoral position is available immediately for a motivated PhD graduate who meets the qualifications and description outlined below. \nQualifications: \n\nA Ph.D. graduate with experience and publications in the fields of molecular biology\, cancer genomics\, and/or mouse genetics.\nAn ideal candidate will have experience with various molecular biology techniques (i.e. DNA/RNA work\, PCR\, qPCR\, Western blot)\, cell culture and/or mouse models.\nMust provide the names of three individuals who can provide recommendations and present a scientific seminar describing his or her previous research.\n\n\nDescription of a Successful Candidate: \n\nA “team” focused scientist\nA self-motivated and driven individual who is able to exhibit exceptional research productivity and take responsibility for independent management of the project\nA detail-oriented researcher who thinks critically to effectively design experiments and solve complex research problems\nA strong ability to take initiative and work independently\nA collaborative\, hands-on researcher who proactively shares knowledge and expertise with lab members and has an interest in helping junior lab members\nExcellent written and oral communication skills\n\n\nJob Functions: Van Andel Research Institute (VARI) provides postdoctoral training opportunities to scientists beginning their research careers. The fellowships are to help promising scientists advance their knowledge and research experience and at the same time support the research endeavors of VARI under the mentorship of a VARI Faculty member. \nWhile this project is currently funded\, an integral part of postdoctoral training is the process of preparing a research proposal and writing a fellowship application. All VARI Postdoctoral Fellows are encouraged to apply for external funding as soon as it is practical and reasonable after hire. Receiving a fellowship award provides recognition for both the fellow and VARI!
URL:https://ces.b2sg.org/event/va-4aug18/
LOCATION:Van Adel Research Institute\, Grand Rapids\, MI\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180803
DTEND;VALUE=DATE:20180905
DTSTAMP:20180803T215247Z
CREATED:20180803T215247Z
LAST-MODIFIED:20180803T215247Z
UID:20453-1533254400-1536105599@ces.b2sg.org
SUMMARY:Postdoctoral Fellow | Cancer Biology
DESCRIPTION:A Postdoctoral Fellow position is available at the Department of Cancer Biology\, Beckman Research Institute at City of Hope. We are looking for a highly motivated postdoctoral fellow interested in studying aging and cancer. Our lab is interested in studying genetic and epigenetic alterations during aging of normal hematopoietic stem cells and in leukemia stem cells that lead to genomic instability\, leukemia development and drug resistance. The lab utilizes bone marrow transplantation and genetic knockout mouse models\, stem cell biology\, and molecular and imaging techniques to study hematopoietic/leukemic stem cells\, and molecular regulation of genomic instability. The outstanding candidate\, particularly with minority background\, may also be eligible for NIH T32 postdoctoral training fellowship in the DNA-damage-response-and-oncogenic-signaling program.  \nThe ideal candidate is expected to have extensive experience in molecular biology and cell biology. Experience with hematology and rodent models preferred. The candidate should be self-motivated\, with a proven track record of productivity. To apply\, please send a cover letter stating your research interests and experience along with a curriculum vitae and the names of three references to Dr. WenYong Chen: wechen@coh.org.  \nEducation and Skills Required for Consideration:\nPhD in Molecular Biology\, Biochemistry\, Stem Cell Biology or related fields.  \nStrong interest in aging and cancer biology.  \nExtensive experience with basic molecular and cell biology skills.  \nExperience in hematology and handling animal models preferred.  \nExperience with epigenetic techniques preferred.  \nExperience with tissue collection\, histology and immunohistochemistry.  \nExperience with cell culture\, immunofluorescence\, flow cytometry\, and cell-sorting.  \nStrong work ethic.  \nGood problem solving skills and passion to follow relevant literature.  \nAbility to conduct independent research.  \nExcellent written and verbal communication skills. Evidence of productivity reflected in first author publications in peer-reviewed journals. 
URL:https://ces.b2sg.org/event/hope-3aug18/
LOCATION:City of Hope\, 1500 East Duarte Road\, Duarte\, 91010\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180727
DTEND;VALUE=DATE:20180908
DTSTAMP:20180727T182932Z
CREATED:20180727T182932Z
LAST-MODIFIED:20180727T182932Z
UID:20450-1532649600-1536364799@ces.b2sg.org
SUMMARY:Postdoc Research Associate
DESCRIPTION:Postdoc Research Associate to perform work in the lab doing molecular biology experiments as well as our novel genetically engineered mouse models of kidney cancer. Basic cell and molecular biology techniques will be used such as mammalian cell culture\, transfection\, anchorage-independent growth assays. \n\n\n\n\nMinimum Qualifications: \nPh.D.Ph.D. biomedical sciences or related.
URL:https://ces.b2sg.org/event/unc-27jul18/
LOCATION:University of North Carolina – UNC-Chapel Hill\, Chapel Hill\, NC\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180724
DTEND;VALUE=DATE:20180826
DTSTAMP:20180724T230404Z
CREATED:20180724T230050Z
LAST-MODIFIED:20180724T230404Z
UID:20445-1532390400-1535241599@ces.b2sg.org
SUMMARY:Associate Scientist | Epigenetics
DESCRIPTION:We are seeking a highly motivated\, positive and engaged team player to join our Epigenetic Discovery group. The successful candidate will work on drug discovery projects focused on Epigenetic and Transcriptional targets. Specifically\, the candidate will be expected to design\, develop and execute experiments that include new target validation\, identification of biomarkers\, elucidation of mechanism of action\, executing existing cell based assays\, and evaluating regular lists of chemical matter to support ongoing SAR efforts. Experience with chromatin IP (ChIP) is highly desired. In addition\, the candidate will assist in creating stable cell lines\, and developing and optimizing new cell based assays to support drug discovery efforts. \nResponsibilities will include\, but are not limited to\, the following \n\nIndependently design\, plan and execute scientific experiments\nAnalyze and interpret scientific data\, troubleshoot and suggest new directions\nConduct routine assays to confirm hits from primary screens and support ongoing SAR efforts\nDevelop\, trouble shoot and optimize new cell based biomarker and functional assays\nAccurately maintain written reports and organize data\nPresent projects in team\, department and project review meetings\nIndependently review current literature pertaining to oncology\, epigenetics\, transcriptional regulation and related assays\n\nExperience/Skills/Knowledge Required \n\nMaster’s degree in a scientific discipline with at least 6 years work experience\, or Bachelor’s degree with at least 8 years work experience.\nIn-depth knowledge of cancer biology and epigenetics\nFamiliarity with drug discovery process for epigenetic and transcriptional targets in oncology\nExperience with target ID / validation efforts\nExperience in executing and developing cell-based assays\, and small molecule hit confirmation efforts\nExperience in molecular and cell biology techniques including cell culture\, transfection and transduction techniques (overexpression\, RNAi\, CRISPR)\, stable cell line generation/validation\, viability assays\, functional/phenotypic assays such as viability and apoptosis in 2D and 3D settings\, real time PCR\, protein assays such as immunoblotting and/or protein simple\, RNA assays including qPCR and/or Nanostring\, microscopy. Experience in ChIP assays is desired\nHighly motivated\, positive\, capable of multitasking\, attention to detail\, and innovative\nExcellent time management and organizational skills\, strong written and oral communication skills\, ability to think creatively and solve problems are essential
URL:https://ces.b2sg.org/event/celgene-24jul18/
LOCATION:Celgene San Francisco\, 1500 Owens St\, CA\, 94158\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180723
DTEND;VALUE=DATE:20180825
DTSTAMP:20180723T091227Z
CREATED:20180723T091111Z
LAST-MODIFIED:20180723T091227Z
UID:20440-1532304000-1535155199@ces.b2sg.org
SUMMARY:Post Doctoral Associate
DESCRIPTION:A postdoctoral position is available in the laboratory of Dr. Merav Socolovsky in the Department of Cancer Biology at the University of Massachusetts Medical School. We investigate the process of mammalian blood cell differentiation\, with a focus on epigenetics and the cell cycle. Please visit the Socolovsky Lab Website ( http://labs.umassmed.edu/socolovskylab/) for details on available research areas.\n\n\n\n\nQualifications\n\n\n\nApplicants should have a Ph.D. in Cell\, Developmental or Molecular Biology\, be creative and highly motivated.\n\n\n\n\nAdditional Information\n\n\n\n\n\nPlease send a brief statement of your scientific work and interests\, a CV and the name and email address of three references\, to Merav.socolovsky@umassmed.edu\n\n\n\n\n\n(Please do not apply via the UMMS Career Site)
URL:https://ces.b2sg.org/event/umass-22jul18/
LOCATION:UMass Medical School\,  55 N Lake Ave\, Worcester\, MA\, 01655\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180722
DTEND;VALUE=DATE:20180824
DTSTAMP:20180722T205207Z
CREATED:20180722T205207Z
LAST-MODIFIED:20180722T205207Z
UID:20437-1532217600-1535068799@ces.b2sg.org
SUMMARY:Postdoctoral Fellow
DESCRIPTION:Postdoctoral fellow positions are available immediately at a leading group in the field of prostate cancer research.  The successful applicant will investigate steroid hormone action\, transcriptional control\, and cell signaling in development and tumorigenesis.  Specifically\, the applicants will develop and use novel and advanced biological approaches\, and genetically-engineered mouse models to uncover gene-expression and genomic and epigenetic alterations in cancer initiating cells in order to understand mechanisms underlying tumor initiation\, progression\, and metastasis. \nWe provide a fruitful research and training environment and competitive salary and fringe benefit.  Applicants should submit their curriculum vitae and the names of three references.  See Zijie Sun lab:  http://www.cityofhope.org/people/sun-zijie. \nMinimum Education and Skills Required for Consideration: \nCandidates should have a recent Ph.D. or M.D/Ph.D. degree in Cancer Biology\, Molecular Biology\, Genetics\, Biochemistry\, Cell Biology\, or a related field. Candidates should be highly self-motivated\, strong working ethic and desire to learn\, and a proven track record of productivity.  Previous experience with mouse models of human diseases\, cancer biology\, and cellular and molecular biology is highly desired.
URL:https://ces.b2sg.org/event/hope-22jul18/
LOCATION:City of Hope\, 1500 East Duarte Road\, Duarte\, 91010\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180720
DTEND;VALUE=DATE:20180822
DTSTAMP:20180720T083943Z
CREATED:20180720T083943Z
LAST-MODIFIED:20180720T083943Z
UID:20435-1532044800-1534895999@ces.b2sg.org
SUMMARY:Post-doctoral Fellow | Molecular Biology
DESCRIPTION:About City of Hope \nCity of Hope\, an innovative biomedical research\, treatment and educational institution with over 5\,000 employees\, is dedicated to the prevention and cure of cancer and other life-threatening diseases and guided by a compassionate\, patient-centered philosophy. \nFounded in 1913 and headquartered in Duarte\, California\, City of Hope is a remarkable non-profit institution\, where compassion and advanced care go hand-in-hand with excellence in clinical and scientific research. City of Hope is a National Cancer Institute designated Comprehensive Cancer Center and a founding member of the National Comprehensive Cancer Network\, an alliance of the nation’s 20 leading cancer centers that develops and institutes standards of care for cancer treatment. \nRequisition number 14254 \nPosition Summary and Key Responsibilities:\nPostdoctoral Research Fellow\, Dr. David Chen Laboratory – Department of Systems Biology\, Beckman Research Institute Dr. David Chen’s laboratory in Systems Biology is focused on the epigenetic mechanisms underlying the therapeutic resistance in cancers. This laboratory is skilled in high-throughput CRISPR genetic screens for de novo therapeutic target discovery. They also utilize next-generation sequencing (NGS) for epigenomic and transcriptomic analyses (ChIPseq\, ATACseq\, RNAseq\, etc.)\, and the patient-derived xenograft (PDX) models for in vivo therapeutic efficacy assessments. In addition\, Dr. Chen’s laboratory is involved in cutting-edge technology development including high-density CRISPR protein scan\, and precision epigenome editing.Dr. Chen received his postdoctoral training from Dr. Scott Armstrong in Harvard Medical School. His laboratory in City of Hope currently consists 3 postdocs\, 1 computational biologist\, and 1 technician. The lab is well funded by a 5-year institutional start-up\, an NIH K99/R00 Award\, and an ASH Scholar Award. An additional NIH R01 Award (scored top 3%) is expected to start in 2019. \nQualifications:\nPhD in cell or molecular biology\, genuine enthusiasm for science\, willingness to think beyond established concepts and to try and learn new experimental and analysis tools. The lab takes a team science approach\, so being a nice person and enjoyable to work with is important as well. \nYour application should include in one single PDF :\nCV\, brief motivation statement\, coordinates of three references \nExperience:\nMammalian cell culture\, cell biology (required); Cancer/leukemia-related studies (preferred); Molecular biology\, cloning\, biochemistry (preferred); Animal model studies (preferred); High-throughput sequencing and computational analysis (preferred) 
URL:https://ces.b2sg.org/event/hope-19jul18/
LOCATION:City of Hope\, 1500 East Duarte Road\, Duarte\, 91010\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180719
DTEND;VALUE=DATE:20180821
DTSTAMP:20180719T071548Z
CREATED:20180719T071548Z
LAST-MODIFIED:20180719T071548Z
UID:20433-1531958400-1534809599@ces.b2sg.org
SUMMARY:Post-Doctoral Research Fellow
DESCRIPTION:A postdoctoral position in the laboratory of Dr. Gavin Ha and the Computational Biology Program is available immediately. We are seeking a highly motivated individual who is interested in studying cancer and understanding the genetic and epigenetic basis driving cancer progression. Candidates who are excited about large/complex ‘omics’ data analysis and methods development for cancer research are encouraged to apply. The position has a duration of at least one year with a competitive salary and great benefits. \n\nThe Ha lab is establishing a research program that uses new DNA sequencing technologies to study cancer genomes. The lab is also focused on research involving liquid biopsies\, such as cell-free DNA\, and developing new computational approaches to leverage these data for genome discovery and cancer burden monitoring. The research interests/projects in the Ha lab include: \n\nAnalysis of cancer genomes to understand tumor progression/evolution\, metastatic disease\, non-coding genome alterations\, copy number alterations\, genome rearrangements and 3D structure\, mutational signatures\nDevelopment of novel computational algorithms for long-range (linked-reads or long-reads) whole genome sequencing of tumors\nAnalysis of linked-read whole genome sequencing data to uncover novel alterations driving metastatic prostate cancer\nAnalysis of cell-free DNA in plasma samples from patients under treatment\nDevelopment and analysis of sensitive approaches to detect tumor-derived DNA in cell-free DNA from patient blood plasma\nThe lab will work with collaborators to validate results using functional experiments\nFor examples of recent studies\, see PMID:29909985\, PMID:29109393\, PMID:25060187\n(please use the apply button below)\n\n\nCandidates with strong interest and/or expertise in any of these research areas are highly encouraged to apply \n\nCancer genomics\, liquid biopsies\, tumor evolution/heterogeneity\nApplication of statistical modeling\, algorithm design\, artificial intelligence to study cancer and genetics\nAnalysis of large\, complex genome\, epigenome\, or transcriptome data\n\n\nQualifications:\nApplicants must have a PhD in one of these disciplines: Computational biology\, bioinformatics\, computer science\, data science\, statistics\, computer/electrical engineering\, physics\, or other related fields \nApplicants should have some of the following skills and experience: \n\nWork well in team environments; strong communication/organization skills; detail-oriented\nStrong programming experience (R\, Python\, Matlab\, Java\, C/C++\, Perl or other languages for research)\nExperience with high performance computing environments and cloud computing environments is a plus\nExperience with analyzing sequencing data is considered a strong asset\nApplicants must have a demonstrated publication track record.\nA background in cancer biology (esp in prostate or breast cancer) is considered a strong asset.\n\n\nTo apply\, please submit your application with the following: \n\na several paragraph statement of research interests\nCV\nnames and email addresses of three references\ntwo representative publications or preprints (if available)
URL:https://ces.b2sg.org/event/hutch-18jul18/
LOCATION:Fred Hutchinson Cancer Research Center
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180716
DTEND;VALUE=DATE:20180818
DTSTAMP:20180716T113818Z
CREATED:20180716T113818Z
LAST-MODIFIED:20180716T113818Z
UID:20431-1531699200-1534550399@ces.b2sg.org
SUMMARY:Research Fellow
DESCRIPTION:How to Apply\nA cover letter is required for consideration for this position and should be attached as the first page of your resume. The cover letter should address your specific interest in the position and outline skills and experience that directly relate to this position. \nJob Summary\nThe research in my laboratory is focused on understanding the molecular events important in pancreatic cancer development. A postdoctoral or research specialist position is now open for projects aimed at understanding pancreatic cancer biology. Research will be performed utilizing a variety of in vitro and in vivo approaches. \nResponsibilities*\nThe applicant is required to function in an independent fashion and be responsible of his/her own research project. In particular\, he/she will be expected to be able to design experiments\, initially under the PI’s guidance\, conduct experiments\, process and analyze data\, and potentially develop new and/or revise research methodologies. In addition\, the candidate will be expected to present his/her own work both at lab meetings as well as scientific conferences and to critically analyze literature relevant to the research. The successful candidate will be expected to be proficient at scientific writing\, and be able to prepare research papers. While funding is currently available for the position\, the candidate will be strongly encouraged to apply for his/her own funding\, under the PI’s guidance. \nAdditional work related tasks\, similar to but not specifically outlined above\, may be needed in position and while study continues to progress. \nRequired Qualifications*\nA doctoral degree and familiarity with basic laboratory techniques in molecular biology field is required for this position. Previous experience in the field of bioinformatics\, epigenetics\, and in vivo mouse models is a plus\, but not required. Excellent verbal and written communication skills are required. \nDesired Qualifications*\n\nThe candidate will be expected to be familiar with bioinformatics\, basic molecular and cell biology techniques\, and in vivo mouse model studies.\nAdditional expertise in epigenetics is a plus.
URL:https://ces.b2sg.org/event/mi-16jul18/
LOCATION:University of Michigan\, 500 S State St\, Ann Arbor\, MI\, 48109\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180715
DTEND;VALUE=DATE:20180817
DTSTAMP:20180715T182805Z
CREATED:20180715T182805Z
LAST-MODIFIED:20180715T182805Z
UID:20429-1531612800-1534463999@ces.b2sg.org
SUMMARY:Research Fellow
DESCRIPTION:The Arthanari Lab is seeking for a highly motivated postdoctoral candidate with expertise in transcriptional biology. Our laboratory works at the interface of structural biology\, drug discovery and mechanistic biology\, focusing on transcription factors and there interactions with co-activators and mediators (e.g. Nature. 201625;530(7591):485-9 ; Nature 2008. 452 (7187): 604-9) .Research efforts will be focused on the intersection of cancer biology/genetics and immune-oncology.\n\n\n\nQualifications\n\n\n\nThe candidate is expected to have a comprehensive understanding of signaling pathways\, epigenetics and transcription regulation. Experience in technical skills including cell culture\, somatic genetic analysis (e.g.\, CRISPr\, si\, sh RNA knockdown and rescue)\, protein biochemistry\, assay design and development and biological applications to advance discovery are preferred. The individual should be independent and passionate about science and have an established record of creativity\, ability to work in teams and strong publication record in peer-reviewed scientific journals.
URL:https://ces.b2sg.org/event/dfci-15jul18/
LOCATION:Dana-Farber Cancer Institute\, 450 Brookline Avenue\, Boston\, MA\, 02215\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180714
DTEND;VALUE=DATE:20180816
DTSTAMP:20180714T152410Z
CREATED:20180714T150204Z
LAST-MODIFIED:20180714T152410Z
UID:20426-1531526400-1534377599@ces.b2sg.org
SUMMARY:Postdoc Research Fellow
DESCRIPTION:The Postdoc Rsh Fellow\, Epigenetic will function under the supervision of a Senior Scientist and Director of the Division of Genetics and Epigenetics. The laboratory has a long standing research program on epigenetics and DNA methylation in normal human development and in common diseases\, including cancer\, Down syndrome\, Alzheimer’s disease and other neurodegenerative disorders\, and autoimmune diseases. Areas of current emphasis include mechanistic studies on genetic-epigenetic interactions that occur in cis and in trans\, using both human samples and mouse models\, and the use of epigenomic mapping as a ‘post-GWAS’ method to identify genes and DNA variants that underlie disease susceptibility. We are also studying epigenetically-acting anti-cancer drugs\, seeking to understand how these agents affect tumor cells and stromal and immune system cells in the tumor microenvironment. Opportunities for post-doctoral training in our group therefore encompass the areas of genome and epigenome analysis using whole genome and targeted approaches in human samples and informative mouse models\, the development of useful bioinformatic methods\, and pre-clinical studies of epigenetically-acting anti-cancer therapies and their effects on the tumor microenvironment in tumor-prone mouse models.\n\n\n\nResponsibilities\n\n\n\n1. Design and perform whole genome and epigenome analyses in human samples and appropriate mouse models\, for understanding mechanisms of disease susceptibility. 2. Develop and apply useful bioinformatic approaches to genomic and epigenomic data for testing mechanistic hypotheses. 3. Present results in internal and external research forums. 4. Participate in grant and manuscript writing\, as appropriate. 5. May design and conduct animal studies using murine models of cancer and Down syndrome. 6. May design and conduct immunological profiling studies in mouse models of Down syndrome and cancer.\n\n\n\nQualifications\n\n\n\nEducation\, Knowledge\, Skills and Abilities Required: 1. Hold a Ph.D. or M.D. Degree from an accredited medical school or graduate level institution. 2. Minimum publication or in preparation of two articles as first author in high quality peer-reviewed scientific journals. Education\, Knowledge\, Skills and Abilities Preferred: 1. Preferred methodologies include genomics/epigenomics\, bioinformatics\, and/or molecular analyses of cells and tissues in mouse models of human disease. 
URL:https://ces.b2sg.org/event/hmh-14jul18/
LOCATION:Hackensack University Medical Center\, 30 Prospect Ave\, Hackensack\, NJ\, 07601\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180713
DTEND;VALUE=DATE:20180815
DTSTAMP:20180713T112115Z
CREATED:20180713T112115Z
LAST-MODIFIED:20180713T112115Z
UID:20424-1531440000-1534291199@ces.b2sg.org
SUMMARY:Bioinformatics Research Scientist - Oncology
DESCRIPTION:Overview: \n\n\nProvides expert bioinformatics support for pediatric oncogenomics research. Collaborates with Oncology investigators to enhance understanding of cancer biology through in-depth computational analysis of genomic datasets obtained from primary cancer samples and experimental models. Applies known methods and/or develops novel computational and statistical methods to help analyze genomic data and associated information\, including gene expression\, SNP chip\, array-CGH\, epigenetic\, microRNA and high-throughput sequencing data. Assists in building necessary software infrastructure and tools to facilitate analysis. Assists in preparing and submitting manuscripts for publication and participates in independent bioinformatics research.\n\n\nMinimum Experience \n\n\n\nPh.D which must include research related to bioinformatics (such as analysis of sequence data\, microarrays\, SNPs\, image data\, proteomics data\, or biological pathways; development of algorithms\, statistical methods\, or scientific software); OR If Ph.D with no bioinformatics research\, then two (2) years of pre-or postdoctoral experience in Computational Biology or Bioinformatics research is required\nExperience with programming languages such as Perl\, C\, or Java required\n\n\n\nMinimum Education \n\n\n\nPh.D. in Bioinformatics\, Computational Biology\, Biochemistry\, Molecular Biology or related field required
URL:https://ces.b2sg.org/event/stjude-13jul18/
LOCATION:St. Jude Children’s Hospital\, 262 Danny Thomas Pl\, Memphis\, TN\, 38105\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180712
DTEND;VALUE=DATE:20180814
DTSTAMP:20180712T121500Z
CREATED:20180712T121500Z
LAST-MODIFIED:20180712T121500Z
UID:20422-1531353600-1534204799@ces.b2sg.org
SUMMARY:Postdoctoral Scientist - Cancer Biology
DESCRIPTION:The George Washington University invites applications from outstanding scientists interested in contributing to the research program of the recently established George GWCC. Areas of particular interest are cancer epigenetics\, cancer immunology and immunotherapy\, and viral/microbial oncology. Examples include gene regulation\, signal transduction\, cancer genetics\, and functional genomics and proteomics. \nThe GWCC at George Washington University has an immediate opening for a Post-Doctoral Scientist position in the laboratory of Dr. Mamta Gupta to study role of epigenetic marks\, including histone modifications and long non-coding RNAs in the pathogenesis of lymphoma. \nThe Post-doctoral Scientist utilizes several techniques including DNA methylation and histone marks\, RNA-IP\, ChIP assay\, Molecular cloning\, mass spectrometry\, site directed mutagenesis\, in-vitro transcription. \nDuties include: \n\nInterprets assay results\nSummarizes findings\nAssist with manuscript preparation.\nPerforms other work related duties as assigned. The omission of specific duties does not preclude the supervisor from assigning duties that are logically related to the position\n\n\nMinimum Qualifications: \nQualified candidates will hold a PhD in a related discipline. Degree must be conferred by the start date of the position \nAdditional Required Licenses/Certifications/Posting Specific Minimum Qualifications: Preferred Qualifications: \nPh.D in biochemistry\, molecular biology\, immunology or related field preferred. \nStrong experience in Immunology\, Epigenetics\, Cancer biology and animal handling\, in addition to some of the following laboratory techniques: tissue culture\, mouse models\, immunological techniques\, molecular biology\, flow cytometry and cellular biology etc. desired.
URL:https://ces.b2sg.org/event/gwu-12jul18/
LOCATION:George Washington University\, 2121 I St NW\, Washington\, DC\, 20052\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180711
DTEND;VALUE=DATE:20180813
DTSTAMP:20180711T155533Z
CREATED:20180711T155533Z
LAST-MODIFIED:20180711T155533Z
UID:20419-1531267200-1534118399@ces.b2sg.org
SUMMARY:Postdoctoral Fellowship - Genetics\, Epigenetic Regulation
DESCRIPTION:Positions of two postdoctoral scientists are open now in the Chen laboratory ( https://www.cityofhope.org/faculty/jianjun-chen ). Our group is interested in discovering novel genetic and epigenetic regulations and deciphering their underlying molecular mechanisms in normal developmental processes (e.g.\, hematopoiesis) and tumorigenesis (e.g.\, leukemogenesis). We cover research areas with relevance to Hematology\, Immunology\, and Cancer Biology\, with an emphasis on RNA epigenetics (mainly focusing on the N 6 methyladenosine (m 6 A) modification) and DNA epigenetics (mainly focusing on the TET1/2/3-mediated DNA demethylation) associated basic and translational research. Our research involves experiments with primary human cancer cells\, cancer and stem cell transplantation models\, mouse genetics\, classic molecular\, biochemistry and cell biology\, functional genomics\, signal transduction\, and large-scale data analysis and computational biology.  \nMinimum Education and Skills Required for Consideration:\nThe candidates for the Postdoctoral scientist positions should have a Ph.D. and/or M.D. degree(s)\, and a solid background in biochemistry\, mouse model studies\, hematology\, epigenetics\, immunology\, pathology\, and/or stem cell research is preferred for. The candidates should not have more than three years of postdoc training experience. The candidates should be highly motivated individuals with the ability to work in a team environment and with good oral and written communication skills in English.  \nApplication:\nPlease apply to this job posting. Additionally\, your application\, including CV\, brief motivation statement\, and contact information of three scientific mentors (references)\, should be saved as a single PDF. The PDF file can be sent to Dr. Jianjun Chen ( jianchen@coh.org ) directly. 
URL:https://ces.b2sg.org/event/hope-11jul18/
LOCATION:City of Hope\, 1500 East Duarte Road\, Duarte\, 91010\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180630
DTEND;VALUE=DATE:20180802
DTSTAMP:20180701T013651Z
CREATED:20180701T013206Z
LAST-MODIFIED:20180701T013651Z
UID:20416-1530316800-1533167999@ces.b2sg.org
SUMMARY:Postdoctoral Fellow - Cancer Biology (Myeloma)
DESCRIPTION:Translational Development at Celgene is pleased to present a growth opportunity for outstanding post-doctoral fellows with a passion for hematology-oncology research and clinical development towards improved outcomes in myeloma patient healthcare. The multiple myeloma Translational Development team currently employs state of the art platforms and analytics to address the most important questions that will drive the current and next generation of therapeutic development for myeloma patients. \nThe successful candidate will become part of diverse team with a unified bench-to-bedside vision in precision healthcare and diagnostic approaches to biomarker utilization. The overarching goal of the successful candidate will be to provide\, through passionate research efforts\, clinically implementable information to better understand how patient characteristics\, malignancy biology and immune context features align to define patient outcomes from treatment with portfolio therapeutics and enable rationale combo design. This fellowship will work alongside top shelf scientists with deep knowledge of myeloma disease biology and further expertise including genomic definition of risk and outcomes\, immune characterization\, definition of response and tumoral evolution using single cell platforms and lab-based screens to better understand mechanistics of clinically-observed phenomenon. \nSkills/Knowledge Required: \n\nPhD in cancer biology\, genetics\, epigenetics\nStrong background in disease or mechanism based studies using modern experimental and computational methods is required.\nKnowledge of myeloma is desirable but not required.\nExperience in heme malignancy related areas\nWhile understanding of epigenetics and epigenetic experimental approaches are not essential\, it is highly desirable.\nPrior experience in molecular\, cellular\, functional and computational methods\nAbility to formulate experimental ideas\nDemonstrated writing and commutation skills\nAbility work in a collaborative team science environment
URL:https://ces.b2sg.org/event/celgene-30jun18/
LOCATION:Celgene\, 86 Morris Ave\, Summit\, NJ\, 07901\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180627
DTEND;VALUE=DATE:20180729
DTSTAMP:20180627T213128Z
CREATED:20180627T212152Z
LAST-MODIFIED:20180627T213128Z
UID:20406-1530057600-1532822399@ces.b2sg.org
SUMMARY:Associate or Full Professor
DESCRIPTION:RPCI is soliciting applications to strengthen its NCI’s Cancer Center Support Grant Program in Cell Stress and Biophysical Therapies (CSBT). Prospective candidates must have a strong record of independent\, extramurally funded program of cancer-related research that will complement the ongoing CSBT Program. Prospective candidates are expected to have active programs in the following areas: molecular (genetic\, epigenetic and biochemical)\, cellular and systemic mechanisms of organismal response to stresses\, pathologies associated with cancer treatment and aging\, as well as development of new original cancer treatment approaches. Proven ability to acquire extramural funding\, along with a strong publication record and other indications of academic activity and visibility are required.  \nRPCI is the world’s oldest cancer center established in 1898\, which is known for numerous basic science and translational discoveries in oncology. RPCI is a NCI-recognized Comprehensive Cancer Center that runs multidisciplinary research combining\, under the umbrella of its CCS Grant\, multiple Programs aimed at understanding\, preventing and curing cancer. It has state-of-the-art research infrastructure enabling all aspects of modern biomedical research – from discovery work towards clinical validation – and provides a highly stimulating academic and clinical environment.
URL:https://ces.b2sg.org/event/rpci-27jun18/
LOCATION:Roswell Park Cancer Institute\, 665 Elm St\, Buffalo\, NY\, 14203\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180624
DTEND;VALUE=DATE:20180726
DTSTAMP:20180624T135018Z
CREATED:20180624T134841Z
LAST-MODIFIED:20180624T135018Z
UID:20401-1529798400-1532563199@ces.b2sg.org
SUMMARY:Associate Scientist
DESCRIPTION:Pfizer’s Oncology Research Unit (ORU) in La Jolla\, California is seeking an Associate Scientist focused on translating basic discoveries in the field of cancer epigenetics into novel therapeutics. \nOur ideal candidate will work within in a collaborative team environment to perform laboratory-based research. The candidate employ genetic and pharmacological to discover and confirm candidates for novel cancer therapeutics. As a member of the group\, you will also be involved in mechanism-of-action studies\, the interpretation and presentation of data\, and will function as an integral member of the team to advance new targets. The successful candidate will have experience in state-of-the-art techniques in epigenomic profiling (ATAC-seq\, ChIP-seq) as well as a basic understanding of epigenetic regulation in the tumor microenvironment. \nROLE RESPONSIBILITIES \nWill report into a team leader within the Epigenetics group. Expected to collaborate with scientists within the Oncology Research Division and across partner lines including Chemistry\, Global Business Technology\, Pharmacokinetics\, Dynamics &Metabolism\, Drug Safety R&D\, Pharmaceutical Science\, and compound management. \nPrimary Duties: \nWork as part of project teams to design\, execute\, analyze/interpret\, and refine experiments ranging from: biochemical and molecular assays\, target modulation\, biomarker assay development. \nDepending upon the stage of project\, specific duties to include: \n\nApplication of genetic and pharmacologic approaches to modulate drug targets in vitro\, and assess functional impact on cancer initiation and progression. This will include functional genomics techniques\, viral vector delivery\, transfection\, antibodies\, small molecules and other pharmacologic approaches to modulate targets in vitro.\nDevelop\, optimize\, and implement assays that constitute the compound screening funnel.\nGenerate engineered cell lines for primary and secondary pharmacology.\nExecute secondary cell-based assays across various technology platforms – qPCR\, ChIP\, RNA-seq\, ATAC-seq\, FACS\, immunofluorescence\, western blotting\, ELISA\, high content screening\, etc.\nApply complex in vitro assays for target validation and secondary pharmacology: spheroid models\, colony forming assays\, 3D co-culture systems.\nCollaborate with in vivo pharmacology group for efficacy testing\, PK/PD and pre-clinical PoC experiments.\nIn addition to efficacy testing\, carry out supporting assays (ELISA\, western blot\, gene expression analysis of tissue lysates) to assess target modulation levels and downstream effects.\nUse electronic data capture/analysis tools such as Excel\, GraphPad\, Biobook\, Spotfire and PowerPoint for experimental documentation and data analysis/presentations.\nPresent research results and methodologies at weekly meetings with immediate supervisor\, at Epigenetic team meetings\, and with members of the oncology research unit as appropriate (example: project team meetings).\nContribute to building a culture that embraces scientific excellence\, urgency\, continuous learning and improvement\, increasing technical skill base and cancer biology expertise; take a proactive role in personal growth and scientific development.\n\nBASIC QUALIFICATIONS \n\nB.S. in Cell Biology\, Molecular Biology (or a comparable biological science) with 0-3 years of related work experience.\nHands on experience with cell-based assays to monitor and analyze effects of target modulation (ELISA\, ICW\, FRET\, Luminescence based assays).\nExperience in functional genomics techniques (CRISPR\, RNAi) for target assessment and generation of cell lines.\nExperience in molecular biology techniques for analysis of chromatin structure/function (ATAC-seq\, ChIP-seq)\, gene expression\, and protein expression\nMust be able to work in a team environment\, have excellent communication skills and be able to present data at project team meetings.\nAbility to master new concepts and techniques quickly.\nStrong attention to detail and organizational skills to manage projects in parallel
URL:https://ces.b2sg.org/event/pfizer-24jun18/
LOCATION:Pfizer – La Jolla\, CA\, 10350 N Torrey Pines Rd\, La Jolla\, CA\, 92037\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180621
DTEND;VALUE=DATE:20180723
DTSTAMP:20180621T213242Z
CREATED:20180621T213242Z
LAST-MODIFIED:20180621T213242Z
UID:20396-1529539200-1532303999@ces.b2sg.org
SUMMARY:Research Fellow
DESCRIPTION:A Research Fellow position is available in the program of Dr. Keith Robertson. For more information about Dr. Robertson’s program\, please see: http://www.mayo.edu/research/faculty/robertson-keith-d-ph-d/bio-20035097 \nThe successful candidate will join the Epigenetic Etiology of Human Disease Laboratory to study the role of DNA epigenetic modifications in human disease. More specifically\, he/she will examine how DNA methylating and hydroxymethylating enzymes regulate their respective DNA epigenetic modifications and how these marks modulate expression and genome stability\, and interface with other epigenetic modifications. Disease focus areas of the laboratory include cancer (hepatocellular and renal)\, obesity\, and diabetes. Specific research areas include application of genome-wide epigenomics methods to decipher DNA methylation/hydroxymethylation defects in cancer and biochemical/cell culture-based techniques to study the regulation and interactions between chromatin remodeling factors (e.g. DNMTs\, TETs\, HMTases) and the roles of their target loci in driving disease. Techniques commonly used in the laboratory include: quantitative RT-PCR\, western blotting\, cell culture\, transfections\, bisulfite sequencing\, DNA immunoprecipitation\, pyrosequencing\, ChIP-qPCR\, ChIP-seq\, next-gen library preparation and sequencing\, Infinium 850k arrays\, bioinformatics analysis\, microscopy\, and biochemical analysis of protein function. Experience in one or more of these areas is a plus. The candidate will play a major role in the preparation of manuscripts that arise from this work and devote 100% effort to these tasks (no patient contact or other responsibilities). \nPosition description \nA Research Fellow at Mayo Clinic is a temporary position intended to provide training and education in research. Individuals will train in the research program of a Mayo Clinic principal investigator. Qualified individuals will demonstrate the potential for research as evidenced by their training and peer-reviewed publications and should become competitive for national research grants. Proof of English proficiency is required for J-1 Short-Term Scholars\, Research Scholars\, Professors\, Specialists\, and Student Interns sponsored by Mayo Clinic. 800146; J2WRTP \nQualifications \nMust have a Ph.D.\, M.D.\, or equivalent doctoral degree in a field deemed relevant by the program. Research Fellow is appropriate for individuals who have completed no more than one prior postdoctoral fellowship\, at Mayo Clinic or elsewhere. Please attach the following required documents at the time of application: \n\nCurrent curriculum vitae and bibliography\nThree letters of recommendation\, signed\, on letterhead\, describing:\n\nRelationship to the applicant.\nPast work/academic performance.\nWork qualities/personal conduct.\nOverall assessment of potential for success in research environment.\n\n\nDoctoral degree certification\, if applicable:\n\nOriginal or notarized copy of diploma or final transcript issued by school (English translation required).
URL:https://ces.b2sg.org/event/mayo-21jun18/
LOCATION:Mayo Clinic\, 200 1st St SW\, Rochester\, MN\, 55905\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180620
DTEND;VALUE=DATE:20180722
DTSTAMP:20180620T145512Z
CREATED:20180620T145512Z
LAST-MODIFIED:20180620T145512Z
UID:20394-1529452800-1532217599@ces.b2sg.org
SUMMARY:Research Lab Technician III/Supervisor
DESCRIPTION:USC’s Keck School of Medicine\, Institute of Urology\, is seeking a Research Lab Technician III/Supervisor to support our Urology Cancer Center epigenetic studies on PSTD and cancer patients pre and post treatment studies. Responsibilities include supervising unit employees and/or student workers as assigned. Assist in orientation and training of unit staff. Plans and conducts research experiments in accordance with laboratory and safety protocols. Independently performs non-routine and complex research laboratory procedures and techniques. Maintains accurate records of procedures used to conduct experiments. Provides input and updates on progress of research as well as selects\, modifies and adapts equipment and maintains sophisticated laboratory and scientific equipment. Controls equipment and supplies inventory. Prepares chemical solutions for experimental use. Researches\, compiles and evaluates background information to enhance planning and design of experiments. \n\nMinimum Education: Bachelor’s degree\, Specialized/technical training \nMinimum Experience: 3 years \nMinimum Field of Expertise: Fully competent and proficient in the operation of sophisticated scientific equipment and independently able to perform complex procedures and techniques with accuracy
URL:https://ces.b2sg.org/event/usc-20jun18/
LOCATION:University of Southern California\, Los Angeles\, CA\, 90007\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180619
DTEND;VALUE=DATE:20180721
DTSTAMP:20180619T144906Z
CREATED:20180619T144906Z
LAST-MODIFIED:20180619T144906Z
UID:20392-1529366400-1532131199@ces.b2sg.org
SUMMARY:Postdoctoral Fellowship
DESCRIPTION:Position Summary and Key Responsibilities:\nPostdoctoral fellow positions are available immediately at Professor Sun’s lab in Beckman Research Institute and the NCI-designated Comprehensive Cancer Center of City of Hope. The successful applicant will join a highly competitive and productive research team to investigate steroid hormone action\, transcriptional control\, and cell signaling in development and tumorigenesis. Specifically\, the applicants will develop and use novel and advanced biological approaches\, and genetically-engineered mouse models to uncover gene-expression and genomic and epigenetic alterations in cancer initiating cells in order to understand mechanisms underlying tumor initiation\, progression\, and metastasis.  \nWe provide a fruitful research and training environment and competitive salary and fringe benefit. Applicants should submit their curriculum vitae and the names of three references. See Zijie Sun lab: http://www.cityofhope.org/people/sun-zijie.  \nMinimum Education and Skills Required for Consideration:\nCandidates should have a recent Ph.D. or M.D/Ph.D. degree in Cancer Biology\, Molecular Biology\, Genetics\, Biochemistry\, Cell Biology\, or a related field. Candidates should be highly self-motivated\, strong working ethic and desire to learn\, and a proven track record of productivity. Previous experience with mouse models of human diseases\, cancer biology\, and cellular and molecular biology is highly desired. 
URL:https://ces.b2sg.org/event/hope-19jun18/
LOCATION:TX
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180618
DTEND;VALUE=DATE:20180720
DTSTAMP:20180618T220824Z
CREATED:20180618T220619Z
LAST-MODIFIED:20180618T220824Z
UID:20388-1529280000-1532044799@ces.b2sg.org
SUMMARY:Postdoc Position
DESCRIPTION:A postdoctoral position is available in the Department of Genetics\, UAB Comprehensive Cancer Center and Center for Free Radical Biology at University of Alabama\, Birmingham. Our group has a longstanding interest in understanding role of oxidative stress\, mitochondria-to-nucleus retrograde cross talk\, mitochondria-induced nuclear genomic instability and mitochondrial genetics in tumorigenesis and other human diseases. \nWe have excellent academic environment and research facilities at the Department of Genetics\, UAB Comprehensive Cancer Center and Center for Free Radical Biology. UAB is a major research university and academic health center that offers a highly interactive scientific environment with state-of-the-art research and core facilities and multidisciplinary work environment. The Department of Genetics fosters collaboration with other basic science as well as clinical departments and the UAB Comprehensive Cancer Center. \nThe candidate is expected to be self-motivated\, resourceful and should have a recently obtained Ph. D. degree. Those with interest and experience in mitochondrial biology\, biogenesis\, oxidative phosphorylation and genetics\, epigenetics such as DNA methylation and transgenic mouse and cell culture models of cancer and/or human diseases are strongly encouraged to apply. \nThe candidate must have experience in mitochondrial techniques\, OXPHOS enzymatic assays\, cell culture\, and standard molecular and epigenetic techniques including cloning\, real time PCR\, transfection\, Southern\, Northern and Western analysis and immunoprecipitation. The candidate with experience in tumorigenesis assay such as soft agar\, matrigel invasion and mouse xenograft are also preferred. The successful candidate is expected to design and perform experiments and interpret data independently. \nInterested applicants should email (in pdf format) a cover letter with the description of research interests and experience\, curriculum vitae\, and contact information of three references to mito@uab.edu. The cover letter should be addressed to: \nKeshav K. Singh\, Ph.D.\nJoy and Bill Harbert Endowed Chair\nProfessor of Genetics\, Pathology and Environmental Health\nDepartment of Genetics\, School of Medicine\nUniversity of Alabama at Birmingham\nKAUL 620\, 1530 3rd Avenue South\nBirmingham\, AL 35294-0024
URL:https://ces.b2sg.org/event/uab-18jun18/
LOCATION:University of Alabama at Birmingham\, 1801 University Blvd\, Birmingham\, AL\, 35233\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180615
DTEND;VALUE=DATE:20180717
DTSTAMP:20180615T144010Z
CREATED:20180615T143948Z
LAST-MODIFIED:20180615T144010Z
UID:20385-1529020800-1531785599@ces.b2sg.org
SUMMARY:Postdoctoral Researcher
DESCRIPTION:The Drapkin laboratory at the University of Pennsylvania (Penn) is seeking to expand its work on tumor development and progression\, cancer genomics and epigenetics\, and lineage dependencies. The goals of the lab are to translate important discoveries into clinically useful diagnostic and therapeutic tools. Several postdoctoral positions are immediately available for outstanding candidates.  \nWe seek candidates with a PhD who have a strong background in biochemistry\, molecular biology\, and basic computational biology.  Preference for candidates with experience in developing and characterizing genetically engineered mouse models will be given. The successful candidate must be well organized and capable of working independently as well as collaboratively. The postdoc should be fluent in English\, possess excellent writing skills\, be able to independently analyze experimental results\, and think creatively. A record of prior publications is required. We interested in highly motivated and talented scientists with a strong work ethic who are committed to solving important questions in cancer biology and are willing to stay at least 4-5 years.  The successful candidate will have completed their graduate degree in or after 2016\, and be a US citizens or permanent residents. \nDr. Drapkin is the Director of the Penn Ovarian Cancer Research Center (OCRC). Established in 2007\, the OCRC serves as a catalyst to promote comprehensive and interdisciplinary research on ovarian cancer. Penn is the oldest and one of the finest medical schools in the United States. It is rich in tradition and heritage and at the same time consistently at the forefront of new developments and innovations in medical education and research. Since its founding in 1765 the School has been a strong presence in the community and prides itself on educating the leaders of tomorrow in patient care\, biomedical research\, and medical education. Penn offers competitive salaries and outstanding benefits. \nVisit the Drapkin lab website for more details: https://www.med.upenn.edu/drapkinlab/ \nPlease submit a motivation letter along with three reference letters and your CV to: \nDr. Drapkin at drapkinlabpostdoc@gmail.com
URL:https://ces.b2sg.org/event/upenn-15jun18/
LOCATION:University of Pennsylvania\, 3400 Civic Center Blvd\, Philadelphia\, 19104\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180614
DTEND;VALUE=DATE:20180716
DTSTAMP:20180614T215724Z
CREATED:20180614T215724Z
LAST-MODIFIED:20180614T215724Z
UID:20383-1528934400-1531699199@ces.b2sg.org
SUMMARY:Postdoctoral Fellowships
DESCRIPTION:Post-Doctoral Fellow positions are available for ambitious and productive applicants in the laboratory of Dr. Rugang Zhang. The lab investigates novel intervention strategies for unmet clinical needs in ovarian cancer and the role of cellular senescence in cancer or tissue aging. The applicant(s) will work in a dynamic scientific environment and has ample opportunities for interactions with leading investigators in ovarian cancer\, epigenetics or cellular senescence through programmatic funding mechanisms. Applicants should have strong background in one or more of the following disciplines: biochemistry\, molecular and cellular biology\, genome-wide approaches to cancer\, animal models of human cancers or aging\, or bioinformatics.\n\nCandidates should have a PhD (or equivalent) degree or should be close to obtaining their doctoral degree. Candidates committed to an academic career are preferred. Curriculum Vitae and three references should be sent to: Rugang Zhang\, Ph.D. The Wistar Institute\, Philadelphia\, PA 19104. Email: rzhang@wistar.org. Website: https://wistar.org/our-scientists/rugang-zhang
URL:https://ces.b2sg.org/event/wistar-14jun18/
LOCATION:Wistar Institute\, 3601 Spruce Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20180613
DTEND;VALUE=DATE:20180715
DTSTAMP:20180613T121358Z
CREATED:20180613T121358Z
LAST-MODIFIED:20180613T121358Z
UID:20381-1528848000-1531612799@ces.b2sg.org
SUMMARY:Postdoctoral Fellow
DESCRIPTION:General Notes \nOne year assignment which can be renewed on an annual basis up to a total of five years. Previous time in a postdoctoral fellow position (whether paid or unpaid) at the University or at any other university counts towards this time limitation (unless the area or discipline changes). Final candidate will need to provide official PhD degree verification documents from the granting institution. \n\n\nRequired Application Materials\n\n\nA Resume is required in order to apply\nA Letter of Interest is required in order to apply.\nA List of 3 References is required in order to apply.\n\n\n\n\nAdditional Information\nPurpose \nPerform research in the lab and program of Dr. Song (Stephen) Yi\, Principal Investigator and Assistant Professor of Oncology at the LIVESTRONG Cancer Institutes. \n\nEssential Functions \nUse systems and computational biology\, bioinformatics\, and proteomics approaches to identify genetic and epigenetic biomarkers\, and synthetic lethal mechanisms underlying cancer and immunity for personalized medicine. Perform bioinformatics data analyses and integrative mechanistic studies in a collaborative environment. Perform projects utilizing functional data from cell lines\, Patient Derived Xenograft (PDX) models and cancer patients. Perform data analysis include genomics\, proteomics\, network biology\, epigenetics and next-generation sequencing. Publish manuscripts\, write and edit grants\, progress reports. Participate in the design of a project. Lead a research effort in the direction set forth by the PI and the specific project. \n\nMarginal/Incidental functions \nOther related functions as assigned. \n\nRequired qualifications \nPh.D. degree in bioinformatics\, systems and computational biology\, cancer biology\, immunology\, or relevant field within the last three years. The Dell Medical School is especially interested in qualified candidates who can contribute to diversity and excellence within the learning health system. At the Dell Medical School we strive to create a vital\, inclusive health ecosystem. To ensure alignment\, we follow these fundamental values: https://dellmed.utexas.edu/culture. \n\nPreferred Qualifications \nExperience with cancer genomics\, CRISPR screens and next-generation sequencing analysis. \n\nWorking conditions \nMay work around standard office conditions Repetitive use of a keyboard at a workstation
URL:https://ces.b2sg.org/event/uta-13jun18/
LOCATION:University of Texas at Austin in Austin
CATEGORIES:Jobs
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