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X-WR-CALDESC:Events for Cancer Epigenetics Society
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DTSTART;VALUE=DATE:20170909
DTEND;VALUE=DATE:20171010
DTSTAMP:20170909T145331Z
CREATED:20170909T145108Z
LAST-MODIFIED:20170909T145331Z
UID:19047-1504915200-1507593599@ces.b2sg.org
SUMMARY:Postdoctoral Opportunities
DESCRIPTION:Laboratory postdoctoral openings: \n• Studies on isoform-specific signaling by PI 3-kinase in tumor metastasis.\nJonathan M. Backer\, MD – Departments of Molecular Pharmacology and Biochemistry \n• Host-Microbe interactions\, microbial genetics\, metagenomics/metabolomics\, inflammation and cancer.\nSridhar Mani\, MD – Departments of Genetics and Medicine \n• Studies on the pro-metastatic protein S100A4 in host-tumor cell interactions during metastasis.\nAnne R. Bresnick\, PhD – Department of Biochemistry \n• Role of DNA modifying enzymes in epigenetic regulation of normal and malignant hematopoiesis\nMeelad Dawlaty\, PhD – Department of Genetics \n• The role of stem cell programs in breast cancer.\nWenjun Guo\, PhD – Department of Cell Biology \n• Development of a procedure to cure sickle cell disease by gene modification in LT-HSCs.\n• Hematopoietic stem cell aging and expression variability. \nEric Bouhassira\, PhD – Departments of Cell Biology and Medicine (Hematology) \n• Cell signaling in normal biology and cancer.\nMarina Holz\, PhD – Department of Molecular Pharmacology \n• Regulation and physiological role of Endosomal Microautophagy (eMI) selective for soluble\, KFERQ-motif containing substrates\, for which we recently have developed a genetic system \nAndreas Jenny\, PhD – Departments of Developmental & Molecular Biology and Genetics \n• Anti-cancer mechanism of methylthioadenosine phosphate inhibitors.\nVern Schramm\, PhD – Department of Biochemistry \n• New immune checkpoints and cancer immunotherapies.\nXingxing Zang\, PhD – Departments of Microbiology/Immunology\, Medicine (Oncology) and\nUrology \n• Molecular and therapeutic Immunomodulation of the immune system to cure HIV infection and prevent neuroAIDS.\nHarris Goldstein\, MD – Departments of Pediatrics and Microbiology/Immunology \n• Development of small molecule drugs to protect the heart during cancer treatments \nRichard Kitsis\, MD – Departments of Medicine and Cell Biology; Evripidis Gavathiotis\, PhD Departments of Biochemistry and Medicine \n• Potential differences in gene regulation in lungs and lung tumors among individuals\, using genetic and epigenetic techniques.\nSimon Spivack\, MD\, MPH – Departments of Medicine (Pulmonary medicine)\, Epidemiology & Prevention Health and Genetics \n• Molecular analysis of DNA replication and repair at cancer-associated sites in the human genome – Carl Schildkraut\, PhD – Professor\, Department of Cell Biology \nLearn more about the Albert Einstein Cancer Center and the Postdoctoral training opportunities\, research programs and faculty mentors at:\nwww.einstein.yu.edu/cancer \nFor a more detailed description of postdoctoral research projects go to:\nhttp://www.einstein.yu.edu/centers/cancer/resources/postdocs.aspx
URL:https://ces.b2sg.org/event/postdocs-einstein-sept17/
LOCATION:Albert Einstein College of Medicine\, 1300 Morris Park Ave\, Bronx\, NY\, 10461\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170909
DTEND;VALUE=DATE:20171010
DTSTAMP:20170909T135920Z
CREATED:20170909T135920Z
LAST-MODIFIED:20170909T135920Z
UID:19045-1504915200-1507593599@ces.b2sg.org
SUMMARY:Sr Research Assistant - Cancer Biology
DESCRIPTION:The lab is expanding their work on the molecular underpinnings of metastasis and are beginning to translate their findings into novel therapeutic approaches. Novel areas of interest include\, but are not limited to\, the role of epigenetics and metabolism in tumor progression and metastasis. We are also focused in understanding changes in transcriptome repertoire (coding and non-coding events) and the influence of genetic and epigenetic regulators during cancer progression and metastasis. Work in the lab is done in several in vitro as well as in vivo model systems. The lab is currently focusing on modelling prostate cancer in patient derived xenografts and in organoid culture.\n \nThe salary range is min $ 38\,000 mid $ 47\,500 max $ 57\,000.\n\n \nKEY FUNCTIONS:\n1. Animal Studies:   \nPerforming animal studies including injecting tumor cells\, monitoring and recording progress of experiments\, necropsy\, preparation of tissue samples for histological processing.  Animals include “nude” and conventional mice.\n \n2. Tissue Sections: \nPreparing frozen and fixed tissue sections for histological and immunostaining analysis of mouse and human tumor xenografts. Performing double and triple immunofluorescence and immunohistochemistry staining experiments\, including optimization of new antibodies and other reagents.\n \n3. Molecular Cytology Techniques:    \nPerforming molecular cytology techniques\, such as in situ hybridization\, X-gal staining\, BrdU and EdU incorporation\, and detection of hypoxia and cellular senescence.\n \n4. Laboratory Studies:  \nPerforms laboratory studies using complex techniques including tissue culture (maintaining mammalian cells\, growth assays\, drug response assays)\, nucleic acid extraction\, RT-PCR\, immunoblotting\, immunocytochemistry and immunohistochemistry.\n \n5. Laboratory Organization and Monitoring:   \nOrders and organizes supplies for the laboratory.  Performs regular monitoring of safety standards in the laboratory\, maintains records of hazardous materials. \n\nEDUCATION: \nRequired: Bachelor’s degree in one of the natural sciences or related field. \n\nEXPERIENCE: \nRequired: Three years of experience in scientific or experimental research work. With preferred degree\, one year of required experience. \nPreferred: Mouse handling\, and tissue culture.
URL:https://ces.b2sg.org/event/sr-res-asst-mda-sept17/
LOCATION:MD Anderson Cancer Center\, 1515 Holcombe Blvd\, Houston\, TX\, 77030\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/05/MDAnderson.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170908
DTEND;VALUE=DATE:20171009
DTSTAMP:20170908T124916Z
CREATED:20170908T124801Z
LAST-MODIFIED:20170908T124916Z
UID:19036-1504828800-1507507199@ces.b2sg.org
SUMMARY:Bioinformatics Scientist
DESCRIPTION:We are seeking a bioinformatics scientist to join the Exploratory Immuno-Oncology (IO) group in NIBR to help us develop and deliver cutting edge cancer therapies to benefit patients. The bioinformatics scientist position plays a key role in facilitating collaborations between IO investigators and NIBR informatics groups. This position will focus on a wide range of applications supporting exploratory research and biomarker discovery including data acquisition and processing pipelines\, data curation\, visualization\, and statistical analysis. \nThe successful candidate will work closely with IO biologists to provide informatics systems to support the drug discovery process. The ideal candidate should be a creative\, effective collaborator and a highly-motivated team player with a strong understanding of data science.  \nKey responsibilities include:  \n• Work with bioinformaticians\, statisticians and laboratory scientists to determine use-cases\, data processing tool development requirements\, and to package and document new methods. \n• Integrate genetics\, epigenetics\, flow cytometry\, and ‘omics data sets to support large-scale data mining. \n• Implement state-of-the-art methods to answer key immuno-oncology questions. \n• Support cutting-edge pipelines for the processing and analysis of high-throughput data. \n• Provide support for existing analysis systems\, including resolution of data retrieval requests.  \nMinimum requirements: \n• M.Sc. in computer science\, bioinformatics or related discipline. \n• Fluency in R\, Perl\, or Python is a prerequisite; Matlab\, Java and SQL are advantageous \n• Demonstrated Linux shell scripting experience \n• Experience in design and development of scientific data processing pipelines and/or experience in providing support for production of software systems \n• Strong communication skills and a successful track record of collaborating with cross-functional scientific teams \n• Knowledge of oncology\, immunology\, genomics\, and Next Generation sequencing is preferred.
URL:https://ces.b2sg.org/event/novartis1-sept17/
LOCATION:Novartis (MA)\, 250 Massachusetts Ave\, Cambridge\, 02139\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170908
DTEND;VALUE=DATE:20171009
DTSTAMP:20170908T114449Z
CREATED:20170908T114410Z
LAST-MODIFIED:20170908T114449Z
UID:19033-1504828800-1507507199@ces.b2sg.org
SUMMARY:Institute Research Scientist - Translational Biology
DESCRIPTION:The Institute Research Scientist participates in cross-functional research to identify and validate novel oncology targets\, and applies deep biological insights to then translate these findings into novel oncology therapeutic agents to benefit patients. \n\n\nSalary Range: Min $95\,000 – Mid $118\,000 – Max $142\,000 \n\n\nESSENTIAL FUNCTIONS \n\n\n1. Apply and develop basic science tools and methodologies to develop complex strategies and enable advancement of Center projects through leadership and experimental activities.    \n\n2. Apply cutting edge functional genomics approaches to enable systematic investigation into mechanisms of tumorigenesis and drug resistance.\n\n3. Independently design\, execute and interpret in vitro\, ex-vivo and in vivo experiments to validate and explore therapeutic potential of drug targets.\n\n4. Work with research and bioinformatics teams to utilize internal biological and oncogenomic data sets to generate and test biological hypotheses.\n\n5. Work with medicinal chemistry and pharmacology teams as part of drug discovery efforts to validate targets and optimize novel small molecule therapeutics.\n\n6. Lead drug discovery biology efforts to selection of lead candidate molecules and transition into clinical development.  \n \n7. Develop and implement biomarker strategies to guide early clinical development of drugs.\n\n8. Design and develop cell and molecular assays to define mechanism of action for compounds\, identify pharmacodynamic assays to be used in pre-clinical and clinical setting and test patient selection strategies.\n\n9. Develop extensive knowledge and experience in key areas of tumor biology including\, but not limited to oncogenic signaling\, tumor microenvironment\, tumor immunology\, metabolism\, epigenetic deregulation or apoptosis.\n\n10. Adapt to new technologies and find solutions to related program studies.\n\n11. Interpret\, present and report research findings at internal meetings and external scientific conferences. \n\n\n\n\nEducation \n\nRequired: Bachelor’s degree in Biology\, Biochemistry\, molecular biology\, cell biology\, enzymology\, pharmacology\, chemistry or related field. \n\nPreferred: PhD in Biological Science or Medical degree strongly preferred\n\n\nExperience\n\nRequired: Ten years of relevant research laboratory experience. With Master’s degree\, eight years of required experience and with PhD\, two years of required experience. \n\nPreferred: At least two years of relevant experience in oncology research in biotech or pharmaceutical environment. \n\n\n– Experience with genetic (ie RNAi and cDNAs) and pharmacological (i.e. small molecule inhibitors or antibodies) approaches to study target biology utilizing state of the art  molecular biology and biochemistry methods and assays essential to drive projects.\n\n– Experience working with chemists\, in vitro and in vivo pharmacologists to develop and utilize assays in support of the development of small molecules for target validation and as part of compound lead optimization for the development of novel therapeutics is highly desirable.\n\n– A demonstrated track record in the development and implementation of functional genomics strategies to enable systematic investigation into mechanisms of tumorigenesis and drug resistance.\n \n– Broad knowledge of cell culture techniques is required and knowledge of how to utilize in vivo oncology models is desirable. Hands-on experience utilizing genetically engineered mouse models and orthotopic or subcutaneous primary or established tumor cell line xenograft models is desirable.\n \n– Extensive knowledge and experience in key areas of tumor biology including\, but not limited to oncogenic signaling\, tumor microenvironment\, tumor immunology\, metabolism\, epigenetic deregulation or anti-apoptosis as evidenced by publication in  peer-reviewed journals.\n\n– Strong data analysis skills\, ability to interpret results and contribute to the design of follow-up experiments\, troubleshoot issues with assay performance\, and effectively present results and conclusions to co-workers\, collaborators and senior leadership. 
URL:https://ces.b2sg.org/event/inst-res-sci-mda-sept17/
LOCATION:MD Anderson Cancer Center\, 1515 Holcombe Blvd\, Houston\, TX\, 77030\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/05/MDAnderson.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170908
DTEND;VALUE=DATE:20171009
DTSTAMP:20170908T112640Z
CREATED:20170908T112518Z
LAST-MODIFIED:20170908T112640Z
UID:19031-1504828800-1507507199@ces.b2sg.org
SUMMARY:Postdoctoral Fellow
DESCRIPTION:Multiple postdoctoral positions are currently available in the laboratory of Dr. Dustin Schones at the City of Hope. \nWe are broadly interested in exploring the interaction of epigenomic and genomic variation in the development of complex diseases such as obesity\, diabetes and cancer. We utilize integrative approaches combining computational and experimental approaches to study these problems. More information about our research program can be found here: https://www.cityofhope.org/people/schones-dustin \nOngoing projects include: 1) Investigating the environmental stimuli responsible for epigenetic dysregulation of transposable elements and the mechanisms responsible for this\, 2) Examining the potential of therapeutic interventions to suppress epigenetic dysregulation of transposons\, 3) Investigating the molecular mechanisms whereby metabolic diseases mediate epigenetic modifications across the genome\, 4) Examining the causes and consequences of epigenomic variation across populations. \nMinimum Education and Skills Required for Consideration: \n\nA Ph.D. in molecular biology\, computational biology or related fields is required.
URL:https://ces.b2sg.org/event/postdoc-cityofhope-sept17/
LOCATION:City of Hope\, 1500 East Duarte Road\, Duarte\, 91010\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170908
DTEND;VALUE=DATE:20171009
DTSTAMP:20170908T111253Z
CREATED:20170908T111253Z
LAST-MODIFIED:20170908T111253Z
UID:19029-1504828800-1507507199@ces.b2sg.org
SUMMARY:Research Scientist - Leukemia
DESCRIPTION:Dr. Kapil N. Bhalla is currently seeking a Research Scientist who will be responsible for conducting research in his NIH-funded laboratory. The focus of the basic and translational research in this laboratory includes the biology and developmental therapeutics related to epigenetic mechanisms involving histone deacetylases\, methyltransferases and demethylases\, BET proteins\, as well as the chaperone biology of heat shock proteins and their cancer relevant client proteins regulating cell growth\, differentiation and survival of the human leukemia stem/progenitor cells. \n\nThe preferred candidate will possess a Ph.D. in Biology\, Biological Sciences\, Life Sciences or related field; a keen interest and experience in cancer research and excellent English skills (both written and verbal).  The preferred candidate will have completed at least a 3 year Post-doctoral fellowship in an area relevant to the focus of research in Dr. Bhalla’s laboratory. In addition\, have the ability to troubleshoot in the design and conduct the laboratory studies. Experience in molecular studies involving gene transfection\, analysis of gene expression through QPCR\, microarrays\, immunoblots and flow cytometry\, as well as experience in chromatin immunoprecipitation studies\, evaluation of protein biochemistry with 2D gels and the yeast-two-hybrid system\, and tissue culture techniques is required. Experience in the ability to utilize CRISPR technology for gene editing and to utilize confocal microscopy for molecular imaging is highly desired. Experience in xenograft and genetically-engineered animal models of cancer and/or leukemia\, and confocal microscopy is also desired.  An outstanding research environment\, new laboratory and core facilities are provided. \n\nKEY FUNCTIONS \n  \n1. The basic and translational research focus of this laboratory includes epigenetic mechanisms involving histone deacetylases\, methyltransferases and demethylases\, heat shock proteins and their cancer and leukemia-relevant client proteins\, as well as transfection and functional analyses of genes regulating cell death/survival of human cancer cells. Experience in animal studies involving NOD/SCID or nude mice\, and mouse imaging (xenogen and MRI) is highly desirable. Experience in molecular techniques involving plasmid DNA preparations and transfection\, the analysis of gene expression including QPCR\, microarrays\, chromatin immunoprecipitation\, evaluation of protein biochemistry with 2D gels\, animal models\, the yeast-two-hybrid system\, confocal microscopy and tissue culture are also preferred. \n2. Plans\, organizes\, coordinates\, directs\, and participates in scientific research projects.  \nPerforms quality research in relation to current research projects\, and other identified needs. Interprets results of experiments\, and makes necessary changes in procedures when needed.  Compiles data sheets. \n3. Organizes and performs routine procedures involving molecular biology and biochemistry of RNA processing. Requires experience in tissue culture\, DNA & RNA preparation\, PCR\, DNA cloning\, protein synthesis and electrophoresis. \n  \nResponsible for providing laboratory services\, tissue culture\, processing research samples\, and/or cataloging samples as required. Interacts with the principal investigators\, postdoctoral fellows and other research personnel in communicating experimental design and results. \n4. Requires knowledge of standard radiographic techniques. Dark room usage is essential as is use and proper handling of radioisotopes. \nMust be able to comply with all institutional safety policies including Universal Precautions and OSHA standards when handling toxic\, hazardous\, flammable\, or potentially infectious or carcinogenic materials.  This may require wearing common protective garments or equipment such as gloves\, eye protection\, face mask\, gown or lab coat\, etc.  Additionally some procedures may require the use of a fume hood or biological safety cabinet. \n5. Work with laboratory animals such as mice and rats and to perform interventional procedures such as tail vein injections and orthotopic implantations. Retrieves\, maintains\, and catalogs specimen stocks from outside reference laboratories.  Assists in other laboratory activities as needed. \n6. Performs and coordinates scientific experiments in a collaborative effort with other technicians\, postdoctoral fellows\, and staff members.  Monitors work flow as it pertains to the need for supplies\, equipment maintenance and stock solutions.  Performs preventive maintenance on laboratory equipment. \n7. Equipment monitoring on a daily basis verifying correct temperatures of freezers\, refrigerators\, incubators\, etc.  Equipment maintenance on a weekly basis includes cleaning and disinfecting refrigerators and incubators.  Daily counter clean up and disinfection to ensure safety of the laboratory work place.  Bags waste and transports to appropriate refuse area utilizing safety standards and guidelines.  Maintains all safety precautions. \n8. Assigns and reviews work of subordinates\, determines specific goals or objectives to be attained\, evaluates resulting research data\, and revises techniques or approaches to work problems. Supervises the design\, development\, or adapting of equipment used in experiments or research to obtain desired results. Utilizes institutional and departmental databases to perform data retrieval for analysis.  Designs retrieval templates for standard queries.  Apply bio-statistical methods in analyzing clinical data such as pretreatment characteristics\, response to treatment\, toxicities\, and mortality\, etc.  \nConducts Library Work.  Finds and copies journal articles as required.  Reads and understands articles related to ongoing research.  Maintains references in a manual filing system.  Requires good reading and comprehension skills as well as diligence\, patience and ability to carry several heavy books at a time. \n9. Assemble samples\, reagents\, dry or wet ice\, data and packaging materials; draft a cover letter\, accurately and legibly fill out shipping labels; carry package to receiving area on ground floor prior to pick up.  Keep accurate legible logs of outgoing and incoming packages.  For incoming packages\, ascertain contents\, store at appropriate location\, file information sheets and notify principal investigator.  Update pertinent inventory logs. \n10. Compiles\, writes\, and submits reports to superior.  Plans and supervises the training of technicians and other laboratory personnel with respect to proper laboratory techniques\, the use of laboratory equipment\, and safety procedures. \n11. Presents findings of data to PI and prepares scientific documents for publication.  Presents findings of research projects to professional groups and prepares scientific documents for publication.  \n12. Performs related work as required. \nsource:sonj \n\nEDUCATON \nRequired: PhD in one of the natural sciences or related field or Medical degree \n\nEXPERIENCE \nRequired: With PhD\, no experience required. With Medical degree\, two years of experience in experimental or scientific work. \n\nPreferred: Completion of a 3 year post-doctoral fellowship.
URL:https://ces.b2sg.org/event/res-sci-mdanderson-sept17/
LOCATION:MD Anderson Cancer Center\, 1515 Holcombe Blvd\, Houston\, TX\, 77030\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/05/MDAnderson.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170908
DTEND;VALUE=DATE:20171009
DTSTAMP:20170908T110447Z
CREATED:20170908T105852Z
LAST-MODIFIED:20170908T110447Z
UID:19026-1504828800-1507507199@ces.b2sg.org
SUMMARY:Postdoctoral Associate - Breast Cancer
DESCRIPTION:The Slingerland lab of the Braman Family Breast Cancer Institute at the University of Miami’s Sylvester Comprehensive Cancer Center has an exciting opportunity for a Postdoctoral Associate who will carry out advanced independent and/or directed research to achieve research project objectives in areas of cell cycle regulation\, signal transduction\, cancer stem cell biology\, transcriptional regulation and epigenetics. The duties will require the exercise of independent discretion and judgment in carrying out research activities within the predetermined research scope and methodology. Duties assigned to this position involve using in-depth knowledge\, developing research methods\, organizing and implementing complex research plans\, analysis and evaluation of data\, and writing manuscripts for publication of research findings. The Postdoctoral Associate will assist the Principle Investigator who is the Director of the Braman Family Breast Cancer Center and will conduct research\, ensuring that all experiments are appropriately conducted following the policies and procedures of the University of Miami. \nThe minimum qualifications for this position are as follows: Ph.D. in a relevant field of study including cellular and molecular biology\, immunology\, stem cell or cancer research. Candidates must have successfully defended their thesis to be eligible for consideration\, and possess the following characteristics: 1) broad knowledge of cancer research and experience in human cell/tissue culture\, molecular biological techniques\, experimental experience with animal models (prior experience in epigenetics research and inducible mouse models of cancer is desirable but not required). 2) ability to plan\, organize and meet deadlines is required. 3) must be highly motivated and have an ability to pay close attention to detail. 4) excellent communication skills\, both verbal and written\, with the ability to professionally interact and collaborate with others. 5) knowledge and experience using Microsoft Word\, Excel and PowerPoint. 6) ability to successfully manage multiple tasks simultaneously and independently. 7) ability to apply logic and demonstrate problem solving skills.
URL:https://ces.b2sg.org/event/postdoc-umiami-sept17/
LOCATION:University of Miami\, 1320 S Dixie Hwy\, Coral Gables\, FL\, 33146\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170828
DTEND;VALUE=DATE:20170831
DTSTAMP:20170509T085903Z
CREATED:20170507T222515Z
LAST-MODIFIED:20170509T085903Z
UID:17886-1503878400-1504137599@ces.b2sg.org
SUMMARY:Transgenerational Epigenetic Inheritance: Impact for Biology and Society
DESCRIPTION:The conference will combine presentations from leaders in the field of epigenetics and epigenetic inheritance related to behavior\, metabolism and physiology in humans and animal models\, from mental health and epidemiology to bioinformatics and ethics. It will address the question of how epigenetic processes mediate the impact of experiences across one or multiple generations.  Germline and non-germline modes of transmission and challenges for DNA methylation\, chromatin modifications and ncRNAs as mechanisms of epigenetic inheritance will be discussed. The inherent difficulties of this challenging discipline and the innovative approaches that can address these difficulties will be critically discussed. The program includes lectures\, short presentations and poster sessions. It also includes a public lecture (in German) discussing how epigenetics can change our view on health. This public lecture is open to everyone (academics\, journalists and any citizen). \nSpeakers:  \nMarisa Bartolomei\, University of Pennsylvania\, USA \nStefan Beck\, University College London\, UK \nChristoph Bock\, University of Vienna\, AT \nLiran Carmel\, Hebrew University of Jerusalem\, IL \nKatharina Gapp\, Sanger Institute\, Cambridge\, UK \nJohannes Graeff\, Ecole Polytechnique Fédérale\, Lausanne\, CH \nCarlos Guerrero-Bosagna\, Linköping University\, SE \nLeah Houri-Ze’evi\, Tel Aviv University\, IL \nEva Jablonka\, Tel Aviv University\, IL \nJosep Jiménez-Chillarón\, Hospital Sant Joan de Deu\, Barcelona\, SP \nMaurizio Meloni\, University of Sheffield\, UK \nEric Miska\, University of Cambridge\, UK \nRuth Müller\, Technical University Munich\, DE \nMarcus Pembrey\, University College London\, UK \nVardhman Rakyan\, Blizard Institute\, London\, UK \nMinoo Rassoulzadegan\, University of Nice\, FR \nAbhay Sharma\, Dehli University Campus\, IN \nMichael Skinner\, Washington State University\, USA \nAdelheid Soubry\, Catholic University Leuven\, BE \nPeter Spork\, Wissenschaftsautor\, Hamburg\, DE \nMoshe Szyf\, McGill University\, Montreal\, CA \nJorg Tost\, Commissariat à l’Energie Atomique\, Evry\, FR \nErica Watson\, University of Cambridge\, UK \nRachel Yehuda\, Mount Sinai Hospital\, New York\, USA \nThe symposium will be held in the historic main building of ETHZ\, talks and the public lecture in the Auditorium Maximum\, Room 30\, Floor F\, and poster sessions in the aula outside the auditorium.
URL:https://ces.b2sg.org/event/latsis-symposium2017/
LOCATION:ETHZ Swiss Federal Institute of Technology Zurich\, Rämistrasse 101\, Zurich\, Switzerland
CATEGORIES:Meetings
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170827
DTEND;VALUE=DATE:20170928
DTSTAMP:20170827T192430Z
CREATED:20170827T192349Z
LAST-MODIFIED:20170827T192430Z
UID:18988-1503792000-1506556799@ces.b2sg.org
SUMMARY:Postdoctoral Fellow - Myeloma
DESCRIPTION:Celgene is a global biopharmaceutical company leading the way in medical innovation to help patients live longer\, better lives. Our purpose as a company is to discover and develop therapies that will change the course of human health.  We value our passion for patients\, quest for innovation\, spirit of independence and love of challenge. With a presence in more than 70 countries – and growing – we look for talented people to grow our business\, advance our science and contribute to our unique culture. \nSummary/Scope \nA postdoctoral position is available to join the Myeloma Disease group based in Summit New Jersey for a  post-doctoral fellow to pursue a project investigating the role of genetic and epigenetic changes in Myeloma patients using cell lines and patient samples. The candidate is required to have a strong background in disease or mechanism based studies using modern experimental and computational methods. While understanding of epigenetics and epigenetic experimental approaches are not essential\, it is highly desirable. Knowledge of myeloma is desirable but not required. \nQualifications \nPrerequisites: \nPhD in cancer biology\, genetics\, epigenetics \nSkills/Knowledge Required: \n\nPrior experience in molecular\, cellular\, functional and computational methods\nExperience in heme malignancy related areas\nAbility to formulate experimental ideas\nDemonstrated writing and commutation skills\nAbility work in a collaborative team science environment
URL:https://ces.b2sg.org/event/celgene-postdoc-myeloma/
LOCATION:Celgene\, 86 Morris Ave\, Summit\, NJ\, 07901\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170827
DTEND;VALUE=DATE:20170928
DTSTAMP:20170827T205342Z
CREATED:20170827T205326Z
LAST-MODIFIED:20170827T205342Z
UID:19000-1503792000-1506556799@ces.b2sg.org
SUMMARY:Associate Investigator
DESCRIPTION:The Associate Investigator Is A Self-Sustaining Scientist And Has Achieved Recognition In His/Her Field. The Associate Investigator Heads A Laboratory And Is Responsible For The Hiring\, Training And Management Of His/Her Lab Personnel And For Assuring That They Work According To The Baylor Scott & White Research Institute (BSWRI) Standards. While The Associate Investigator May Receive Supplemental Funds From BSWRI\, It Is The Investigator’s Responsibility To Obtain Grants That Will Support His/Her Research And To Produce Data That Is Worthy Of Publication In Leading Journals And Has Patent Potential. The Associate Investigator Is Part Of The BSWRI Faculty And Plays A Role In The Continued Growth And Development Of BSWRI. He/She May Be Asked To Serve On Committees\, Develop Collaborations Or Act As A Liaison With External Departments. \n  \nThe Ideal Candidate For The Associate Investigator Role Will Be A PhD Scientist With A Proven Track Record Of Leading A Research Team\, Securing Their Own Grants\, And Consistently Being Published In Their Field. \n\n• Doctorate Degree Required \n• 4 years of experience required
URL:https://ces.b2sg.org/event/bswh-associate-investigator/
LOCATION:Baylor Scott & White Health (BSWH)\,  3500 Gaston Ave\, Dallas\, TX\, 75246-2017\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170827
DTEND;VALUE=DATE:20170928
DTSTAMP:20170827T204033Z
CREATED:20170827T203705Z
LAST-MODIFIED:20170827T204033Z
UID:18997-1503792000-1506556799@ces.b2sg.org
SUMMARY:Associate Scientist - Biomarker Development Laboratory
DESCRIPTION:An Associate Scientist position is available in the Pathology Biomarker Development laboratory\, in the Department of Pathology. This lab studies molecular biomarkers of diagnostic\, prognostic and therapeutic significance for diseases affecting St. Jude patients. We evaluate the feasibility and clinical utility of novel assays\, to determine whether they may be integrated into clinical diagnostic practice. \n Currently\, our lab is working on utilizing Illumina methylation arrays as a diagnostic tool\, exploring the utility of cell free DNA to monitor response to therapy\, and investigating the use of protein microarrays to identify disease biomarkers and therapeutic targets.  \nPrevious experience with research techniques including genomic analysis\, NGS\, methylation profiling and protein analysis are all strongly preferred. Strong skills in novel assay development and validation are preferred. Candidates with experience in cancer genomics\, genetics or epigenetics and strong problem solving skills are highly encouraged to apply. \n \n\n\n\nMinimum Education:\n\n\n\n\nBachelor’s degree in an appropriate scientific field is required.\n\n \n\n\n\nMinimum Experience:\n\n\n\n\nA minimum of fifteen (15) years of relevant post-degree work experience is required with a Bachelor’s degree\, with at least seven (7) years at the Research Lab Specialist level\nA minimum of fourteen (14) years of relevant post-degree work experience is required with a Master’s degree\, with at least seven (7) years at the Research Lab Specialist level\nA minimum of nine (9) years of relevant work experience including post-doctoral and/or technical staff experience is required with Ph.D.
URL:https://ces.b2sg.org/event/stjude-biomarker-lab/
LOCATION:St. Jude Children’s Hospital\, 262 Danny Thomas Pl\, Memphis\, TN\, 38105\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/05/stjude.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170827
DTEND;VALUE=DATE:20170928
DTSTAMP:20170827T194209Z
CREATED:20170827T194209Z
LAST-MODIFIED:20170827T194209Z
UID:18995-1503792000-1506556799@ces.b2sg.org
SUMMARY:Associate Researcher - Pharmacological Sciences
DESCRIPTION:For laboratory research in genomics and molecular biology of cancer/stem cells in the Department of Pharmacological Sciences is looking to fill a position of research associate. \nThe laboratory research will focus on understanding the role of epigenetic regulators in biological events that control and direct cell fate. We use state of the art equipment and techniques. Training will be provided if needed. \nJob duties \n\nCell culture techniques: regular passaging and infection/transfection. Maintenance of lab stocks of frozen cells and mycoplasma testing\nNGS: RNA isolation and quality control. Library preparation\nAnimal handling: drug delivery by IP and SC methods. Tumor xenograft inoculation and monitoring\nMolecular techniques: qPCR\, WB\, IFF\, IHC\nKeep up to date laboratory records of the experiments performed\nCommunicate results in lab meetings\n\n \nWhat You’ll Bring:\n\nBachelor of Science in Biology or related field\n0-2 years of experience in laboratory\nWillingness to spend most of the time in the laboratory and to perform laboratory maintenance tasks and organization\nKnowledge of MS-excel and word\nMust be very organized
URL:https://ces.b2sg.org/event/sinai-res-pharmacology/
LOCATION:Mount Sinai – Icahn School of Medicine\, 1468 Madison Ave\, New York\, NY\, 10029\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/06/mount-sinai-e1496335480980.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170824
DTEND;VALUE=DATE:20170825
DTSTAMP:20170507T221028Z
CREATED:20170507T215846Z
LAST-MODIFIED:20170507T221028Z
UID:17880-1503532800-1503619199@ces.b2sg.org
SUMMARY:3rd Epigenetic Methyltransferases - Structure\, Mechanism and Inhibition
DESCRIPTION:Speakers: \nRima Al-awar\, Pharmacology & Toxicology\, University of Toronto and Ontario Institute for Cancer Research (OICR)\, Canada. \nMichael Cosgrove\, Biochemistry and Molecular Biology\, State University of New York Upstate Medical University\, USA \nJocelyn Côté\, Cellular and Molecular Medicine\, University of Ottawa\, Canada\n \nJean-François Couture\, Biochemistry\, Microbiology and Immunology\,\n  University of Ottawa\, Canada \nPaul Delgado-Olguín\, Physiology and Experimental Medicine\, The Hospital for Sick Children\, Toronto\, Canada. \nBenjamin Garcia\, Biochemistry and Biophysics\, University of Pennsylvania School of Medicine. USA \nJean-Claude Guillemot\, AFMB Polytech\, Marseille\, France \nIngo Hartung\, Drug Discovery\, Pharmaceuticals\, Bayer\, Germany \nMathieu Lupien\, Medical Biophysics\,University of Toronto\, Canada \nDafydd Owen\, Pfizer\, USA \nMasoud Vedadi\, Pharmacology and Toxicology\, and SGC University of Toronto  \nShaomeng Wang\, Pharmacology and Medicinal Chemistry\,\n University of Michigan\, USA \nKehao Zhao\, Novartis\, USA \n  \nOrganizing committee: Cheryl Arrowsmith\, Santha Santhakumar\, Masoud Vedadi
URL:https://ces.b2sg.org/event/3rd-epigenetic-methyltransferases-aug2017/
LOCATION:Chestnut Residence & Conference Centre\, 89 Chestnut St\, Toronto\, Ontario\, M5G 1R\, Canada
CATEGORIES:Meetings
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/05/sgc-big.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170814
DTEND;VALUE=DATE:20170915
DTSTAMP:20170814T224242Z
CREATED:20170814T224242Z
LAST-MODIFIED:20170814T224242Z
UID:18977-1502668800-1505433599@ces.b2sg.org
SUMMARY:Postdoctoral Research Associate I
DESCRIPTION:The University of Arizona (UA) Division of Pulmonary\, Sleep and Critical Care Medicine is seeking a Postdoctoral Research Associate I. The successful candidate will be involved in independent and collaborative research focusing on translational and clinical genetics and genomics. The successful candidate will have a strong background in the study of pulmonary disease in laboratory animals and humans and vast experience working with in vitro model systems of environmental disease susceptibility. In addition to his/her own experimental procedures\, the postdoctoral fellow will work with other lab members to study genetic and epigenetic determinants of pulmonary disease\, with a focus on chronic obstructive pulmonary disease and cancer. \nThe primary purpose of this appointment is to engage in advanced research training for the postdoctoral fellow in preparation for an independent academic position. Under the mentorship provided by the principal investigator\, the Postdoctoral Research Associate will be engaging in research activities that include: a) daily experimental work in the lab\, b) presenting his/her experimental results both within departmental meetings and in conferences\, and writing manuscripts\, fellowship and grant applications based on his/her research results; and c) working as a member of the principal investigator’s lab team. Knowledge of mass spectrometry from running experiments to analyzing data is required for this position. \n\nDuties & Responsibilities: \n\nDaily experimental work in the laboratory.\n\n\nPresent experimental results within departmental meetings and in conferences.\n\n\nWrite manuscripts\, fellowship and grant applications based on research results.\n\n\nWork as a member of the principal investigator’s team.\n\n\nAssist researchers in the development of study protocols and informed consent documents.\n\n\nArrange secure storage of study documents.\n\n\nPerform molecular biological techniques (e.g.\, Western blot\, gene transfection\, mutagenesis\, plasmid amplification).\n\n\nAdvancement of ELISA methodology for human epidemiological and clinical studies.\n\n\nTrain new laboratory members.\n\n\nParticipate in writing grant proposals and articles.\n\n\nAttend and participate in all lab meetings.\n\n\nThere may be additional duties assigned as it relates to this position.\n\nQualifications: \n\nKnowledge of molecular and cellular biology techniques from running experiments to analyzing data is required for this position.\n\n\nDoctoral (PhD) degree in biomedical sciences or related area.\n\n\nAt least 2 years of research experience in lung biology.\n\n\nAt least 1 year of experience in molecular and cellular biology techniques to study pulmonary disease.
URL:https://ces.b2sg.org/event/uofarizona-res1-aug17/
LOCATION:University of Arizona\, Tuscon\, AZ\, 85721\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170814
DTEND;VALUE=DATE:20170915
DTSTAMP:20170814T202529Z
CREATED:20170814T202529Z
LAST-MODIFIED:20170814T202529Z
UID:18971-1502668800-1505433599@ces.b2sg.org
SUMMARY:Application Scientist
DESCRIPTION:10x Genomics is looking for an outstanding individual to join the Applications Development group as an application scientist. The applications team interfaces with a variety of external scientists to demonstrate the value of all 10x products. In this role\, you must be able to learn quickly\, creatively solve problems\, track multiple projects and priorities\, identify project risks and communicate effectively. The ideal candidate will have a PhD and experience in stem cell\, immunology or cancer biology.  \nKey Responsibilities  \n\nPerform and troubleshoot complex experiments to support collaborations using 10x genome and single cell solutions\nDevelop and perform validation studies including experiments design\, data analysis and interpretations\nWork with key scientists to develop new applications taking advantages of 10x genomics products\nManage collaboration samples and collaboration related experimental activities\nParticipate in the preparation of scientific materials and other marketing collaterals such as demonstrated datasets and protocols\, webinars and application notes.\n\nIndividuals applying must have a wide knowledge in biology and with an education background in one or more of the following disciplines; molecular biology\, biochemistry\, cell biology\, or genetics. Research experience in an academic or industrial setting is preferred.  \nRequired Skills and Background  \n\nPhD. in stem cell\, immunology or cancer biology\nWork efficiently with a multi-disciplinary team\nDemonstrated collaborative work\nGood oral and written communication skills\nOrganization and documentation skills are a must\nInterest and familiarity to analyze and interpret NGS data\nExperienced with NGS library preparation and troubleshooting\nExperienced with a wide range of molecular biology techniques such as qPCR\, ddPCR and epigenetic techniques (ChIP\, Hi-C\, ATAC-seq). Familiarity with single cell techniques will be a plus.\nDemonstrated work with a wide range of tissue types highlighting an expertise in a wide range of cell biology techniques such as CRISPR\, human iPSCs\nBroad knowledge in cancer\, immuno-oncology\, stem cell\, development\, neurology and/or immunology\nDesire to be part of a rapidly evolving organization\, which requires flexibility and a willingness to learn new techniques and methods
URL:https://ces.b2sg.org/event/10x-appsci/
LOCATION:10x Genomics\, Pleasanton\, CA\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170812
DTEND;VALUE=DATE:20170913
DTSTAMP:20170813T003509Z
CREATED:20170813T003311Z
LAST-MODIFIED:20170813T003509Z
UID:18964-1502496000-1505260799@ces.b2sg.org
SUMMARY:Postdoctoral Fellow
DESCRIPTION:Job Summary: \nThe University of Colorado Denver l Anschutz Medical Campus is seeking applications for a Post-Doctoral Fellow for the Ernst Lab. This full-time position is responsible for: 100 % effort to studying the role of CCDC3 factors within different forms of cancer. \nExamples of work performed: \n\nSet up mouse mating(s);\nTag/tail/genotype progeny;\nAddress any problem issues with mouse colony;\nInteract with animal facility staff;\nMaintain on-line and printed records of animals in colony;\nOrder animals for project as needed;\nUse University system to order reagents and supplies as needed;\nMaintain laboratory stocks and equipment and be responsible for coordinating repairs when needed;\nMaintain lab records of stocks;\nSupervise new trainees\, rotation students\, undergraduates in lab jobs and experimentation;\nMaintain laboratory records for experiments for publication methods and for others to repeat experiments;\nCorrespond with other investigators inside and outside of the CU system regarding collaborations;\nPerform experiments independently;\nPerform experiments with other students\, postdocs to contribute to publications and overall productivity of the group;\nMaintain accurate and current laboratory notebook including all experimental details;\nWrite-up and present experiments in small group meetings;\nTravel and present personal and laboratory projects.\n\nPLEASE NOTE: Candidates will be responsible for travel expenses related to the interview process and any relocation expenses\, if applicable. \n  \nSalary and Benefits: \nThe hiring salary for this position is $47\,484.00. This position is not eligible for overtime compensation. \nThe University of Colorado offers a full benefits package. Information on University benefits programs\, including eligibility\, is located at https://www.cu.edu/employee-services.  \nThe University of Colorado Denver | Anschutz Medical Campus is dedicated to ensuring a safe and secure environment for our faculty\, staff\, students and visitors. To assist in achieving that goal\, we conduct background investigations for all prospective employees. \n  \nThe University of Colorado Denver | Anschutz Medical Campus is committed to recruiting and supporting a diverse student body\, faculty and administrative staff. The university strives to promote a culture of inclusiveness\, respect\, communication and understanding. We encourage applications from women\, ethnic minorities\, persons with disabilities and all veterans. The University of Colorado is committed to diversity and equality in education and employment. \nThe Immigration Reform and Control Act requires that verification of employment eligibility be documented for all new employees by the end of the third day of work. Alternative formats of this ad are available upon request for persons with disabilities. \n  \nQualifications \n  \nMinimum Qualifications: \n\nGraduation from an accredited university with a PhD in Biomedicine or Biochemistry.\nMinimum of 2 years of Cancer/Molecular Biology lab experience.\nExcellent communication skills in English.\nDemonstrates the proficiency in computer software\, equipment operation\, or research technical skills.\n\nCondition of Employment: \nMust be willing and able to pass a national criminal background check \n  \nPreferred Qualifications: \nIn depth experience in at least two of the following areas is desired: \n\nExperience with CCDC3 functions in different forms of cancer\,\nExperience with Bmi-1 induced apoptosis\,\nExperience in autophagy and epigenetic regulators in cancer cells.\n\n  \n   \nSpecial Instructions to Applicants: *Applications are accepted electronically ONLY at www.cu.edu/cu-careers. Required Application Materials: When applying at www.cu.edu/cu-careers\, applicants must include: 1. A cover letter of application which specifically addresses the job requirements and outlines qualifications 2. A current CV or resume 3. The names\, addresses\, daytime telephone numbers and email addresses for three professional references. Questions should be directed to Paul Lopez at Paul.J.Lopez@ucdenver.edu Reference checks are a standard step in our hiring process. You may be asked to provide contact information\, including e-mail addresses\, for up to 5 references if you are referred to the Hiring Authority for an interview. We will notify you prior to contacting both on and off-list references. Please do not submit any of your application material (via email) to the job posting contact.
URL:https://ces.b2sg.org/event/u-colorado-postdoc-aug17/
LOCATION:University of Colorado – School of Public Health\, 13001 E 17th Pl\, Aurora\, CO\, 80045\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170809
DTEND;VALUE=DATE:20170910
DTSTAMP:20170809T163522Z
CREATED:20170809T163232Z
LAST-MODIFIED:20170809T163522Z
UID:18955-1502236800-1505001599@ces.b2sg.org
SUMMARY:Research Fellow - Molecular Pharmacology
DESCRIPTION:Position Summary:  \nThe successful candidate will join the Epigenetic Etiology of Human Disease Laboratory to study the role of DNA epigenetic modifications in human disease. More specifically\, he/she will examine how DNA methylating and hydroxymethylating enzymes regulate their respective DNA epigenetic modifications and how these marks regulate expression and genome stability\, and interface with other epigenetic modifications. Disease focus areas of the laboratory include cancer (hepatocellular\, renal\, and glioma)\, obesity\, and diabetes. Specific research areas include application of genome-wide epigenomics methods to decipher DNA methylation/hydroxymethylation defects in cancer and biochemical/cell culture-based techniques to study the regulation and interactions between chromatin remodeling factors (e.g. DNMTs\, TETs\, HMTases). Techniques commonly used in the laboratory include: quantitative RT-PCR\, western blotting\, tissue culture\, transfections\, bisulfite sequencing\, pyrosequencing\, ChIP-qPCR\, ChIP-seq\, next-gen library preparation and sequencing\, Infinium 850k arrays\, RRBS\, DIP-seq\, bioinformatics analysis\, and biochemical analysis of protein function. Experience in one or more of these areas is a plus. The candidate will play a major role in the preparation of manuscripts that arise from this work and devote 100% effort to these tasks (no patient contact or other responsibilities). The candidate will also participate in meetings (local and national)\, seminars\, and journal clubs. \nResponsibilities: A Research Fellow at Mayo Clinic is a temporary position intended to provide training and education in research. Individuals will train in the research program of a Mayo Clinic principal investigator. Qualified individuals will demonstrate the potential for research as evidenced by their training and peer-reviewed publications and should become competitive for national research grants. Proof of English proficiency is required for J-1 Short-Term Scholars\, Research Scholars\, Professors\, Specialists\, and Student Interns sponsored by Mayo Clinic. 800146; J2WRTP \nQualifications: Must have a Ph.D.\, M.D.\, or equivalent doctoral degree in a field deemed relevant by the program. Research Fellow is appropriate for individuals who have completed no more than one prior postdoctoral fellowship\, at Mayo Clinic or elsewhere. Please attach the following required documents at the time of application: \n\nCurrent curriculum vitae and bibliography\nThree letters of recommendation\, signed\, on letterhead\, describing:\n\nRelationship to the applicant.\nPast work/academic performance.\nWork qualities/personal conduct.\nOverall assessment of potential for success in research environment.\n\n\nDoctoral degree certification\, if applicable:\n\nOriginal or notarized copy of diploma or final transcript issued by school (English translation required).\n\n\n\nRecruiter: Kara Schott
URL:https://ces.b2sg.org/event/mayo-res-aug17/
LOCATION:Mayo Clinic\, 200 1st St SW\, Rochester\, MN\, 55905\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170809
DTEND;VALUE=DATE:20170910
DTSTAMP:20170809T161937Z
CREATED:20170809T161007Z
LAST-MODIFIED:20170809T161937Z
UID:18951-1502236800-1505001599@ces.b2sg.org
SUMMARY:Research Specialist I
DESCRIPTION:The Research Specialist 1 will participate in a research project in a translational cancer genetics laboratory\, including genetic and epigenetic studies of breast cancer. Must be able to perform tasks with minimal supervision. Proficiently perform many laboratory techniques such as cell culture\, extraction of nucleic acids and proteins from cultured cells\, quality control and quantification of nucleic acids and protein samples\, cloning\, sequencing\, quantitative real-time PCR\, and transfection of cells. Maintain complete and accurate experimental records. Collate and analyze data. Summarize results and write papers and abstracts for publication. Contribute to maintenance of equipment and organization of the laboratory. \n50% – clone guide RNA sequences\, grow and transfect commercially available human cell lines and harvest them for analysis \n15% – extract DNA for sequencing. \n15% – Prepare preliminary and final reports describing the results of sequence analysis. Record accurate data into computer database. \n10% – Participates in scientific writing for future journal publication and grant reports. \n5% – Participate in laboratory tasks\, such as routine laboratory maintenance \n5% – Participates in training sessions and workshops. \nBachelor’s degree in Biology required.   \nTwo years of previous lab experience\, including cell culture and molecular genetics required. \nKnowledge of CRISPR/CAS 9 technology\, cell culture techniques and DNA sequence analysis\, genetics\, molecular biology. \nKnowledge in relevant scientific field required.\nKnowledge of research techniques or methods required.\nKnowledge of regulatory policies and procedures required.\nAnalytical skills required.\nProblem-solving skills required.\nAttention to detail required.\nOrganizational skills required.\nVerbal and written communication skills required.\nAbility to work independently and as part of a team required.\nKnowledge of Microsoft Excel.\nAttention to detail and good communications skills.\nKnowledge of Microsoft Office required.   \n 
URL:https://ces.b2sg.org/event/uchicago-res1-aug17/
LOCATION:University of Chicago\, 5801 S Ellis Ave\, Chicago\, IL\, 60637\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170801
DTEND;VALUE=DATE:20170902
DTSTAMP:20170801T125244Z
CREATED:20170801T125244Z
LAST-MODIFIED:20170801T125244Z
UID:18931-1501545600-1504310399@ces.b2sg.org
SUMMARY:Postdoctoral Research Associate
DESCRIPTION:The Chapkin laboratory at Texas A&M University has an opening for a PhD graduate with an interest in one or more of the following areas: obesity\, intestinal stem cells\, epigenetics\, metabolic profiling in preclinical models\, gut-microbe crosstalk\, membrane biology\, immunology and/or computational biology/ bioinformatics. Our lab studies the effects of natural dietary and microbial bioactive molecules on chronic diseases\, with particular interest in molecular mechanisms of action. Methods include flow cytometry\, cell culture\, confocal (FLIM\, FRET\, TIRF) super resolution microscopy\, metabolite analysis\, RNA Seq\, ChIP Seq\, microRNA analysis among others. Pathways of interest include Wnt signaling\, lipid rafts/cytoskeletal interaction\, AhR\, Myc and EGFR/Ras-dependent signaling. \nActive projects in the lab include:\n– Effects of dietary and microbial-derived compounds on cell membrane structure and function.\n– Development of a novel noninvasive methodology to monitor host/microbe interaction.\n– Investigation of the role of dietary and microbial ligands as modifiers of inflammation and colon cancer development.\n– Synergistic effects of systemic and luminal metabolites on intestinal stem cells and differentiated colonocytes. \nThe successful candidate will be highly motivated\, comfortable with technical challenges and problem solving and able to work collaboratively. \nDuties include: Designing and conducting research projects\, writing manuscripts\, developing new methodologies for the lab \nOccasional Duties \nOther job related duties as required. \nRequired Education:\nPh.D. in any biological science. \nPreferred Education:\nPhD in biochemistry\, cell biology\, biology\, physiology\, genetics or nutrition. \nRequired Experience:\nExperience in molecular and cell biology and cell culture. \nPreferred Experience:\nExperience in cell biology\, fluorescence microscopy\, and/or stem cell biology\, and/or computational biology\, and/or obesity research. \nRequired licenses\, certifications\, or registrations:\nNone. \nPreferred licenses\, certifications\, or registrations:\nNone. \nRequired special knowledge\, abilities\, and skills:\nFamiliarity with appropriate laboratory equipment. Ability to effectively utilize a computer and applicable software to create databases\, perform statistical analyses\, present data and perform other computer related tasks as directed by the supervisor. \nPreferred special knowledge\, abilities\, and skills:\nTrouble shooting techniques\, manuscript and research proposal preparation. \nOther requirements or other factors:\nAbility to multi task and work cooperatively with others. \nDocuments associated with this posting \nCover Letter – required\nC.V. – required 
URL:https://ces.b2sg.org/event/tamu-postdoc-res-aug17/
LOCATION:Texas A&M\, 600 John Kimbrough Boulevard\, College Station\, TX\, 77843\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170801
DTEND;VALUE=DATE:20170902
DTSTAMP:20170801T123226Z
CREATED:20170801T123226Z
LAST-MODIFIED:20170801T123226Z
UID:18929-1501545600-1504310399@ces.b2sg.org
SUMMARY:Research Associate II
DESCRIPTION:To enable Guardant Health to lead the disruption of cancer treatments through non-invasive cancer screening\, the Technology Development Team is seeking a highly motivated Research Associate to help develop\, test\, and improve sample preparation technologies for rare variant and epigenetic studies with next-generation sequencing. At Guardant\, we leverage the most advanced technologies and work with leaders in many different fields to create the most impactful and meaningful technologies for cancer management.  \nAs a Research Associate supporting product and technology development\, you will work with members within the team and interface with multiple teams including process engineering\, clinical operations\, research operations\, and bioinformatics. You will be hands on in the lab and be required to design\, implement\, and validate new technologies related to liquid biopsy sequencing assays for the early detection\, treatment\, and monitoring of all cancer types.  \nRESPONSIBILITIES  \n\nOperate next generation sequencing instruments\nRun sequencing sample preparation assays in medium to high throughput environment\nTest and improve new sequencing sample preparation assays\nLog and track research samples throughout sequencing workflow\nMaintain appropriate inventory of lab supplies\nBring a can do attitude to solve new and challenging problems in a high pace environment\nAnalyze data and troubleshoot issues within the tech dev team and among other teams\nCollaborate with all functions within project teams\nEngage in early design of products and perform experiments both independently and under the supervision of Senior team members within Tech Dev and Bioinformatics groups\nBe able to present updates\, write reports and SOPs\, and contribute to technical discussions\n\nABOUT YOU  \n\nThe ability to handle biological samples (i.e. tissue\, biofluid\, etc) is a must\nExcellent written and oral communication skills is a must\nProfessional hands-on experience in industrial setting in genomics field is a plus (operational experience is preferred)\nHands-on experience in running sequencing platforms and assays is a plus\n\nWe would like to talk with you about our exciting projects we currently have ongoing. 
URL:https://ces.b2sg.org/event/guardant-res-aug17/
LOCATION:Guardant Health\, 505 Penobscot Dr.\, Redwood City\, CA\, 94063\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170801
DTEND;VALUE=DATE:20170902
DTSTAMP:20170801T105222Z
CREATED:20170801T105222Z
LAST-MODIFIED:20170801T105222Z
UID:18925-1501545600-1504310399@ces.b2sg.org
SUMMARY:Assistant Professor - Oncological Sciences
DESCRIPTION:The Department of Oncological Sciences has a position open for an Assistant Professor in the tenure-line\, to maintain and enhance our robust basic and cancer-focused research portfolio. The successful candidate will have a track record in the biochemistry and biophysics of signaling in cancer cell biology. Requirements include a PhD\, postdoctoral training\, and a track record of scientific excellence in this field\, including publications of high impact. Duties involve a major commitment to direct research\, complemented by involvement in teaching and service: 85% direct research\, 10% Department/School of Medicine teaching\, 5% Department/HCI/School of Medicine service. The candidate will oversee the HCI zebrafish shared resource and consult with and mentor faculty in the use of zebrafish models of cancer. \nDepartmental strengths include epigenetics and transcriptional regulation\, mouse and zebrafish models of cancer\, and cancer cell biology – including signaling\, motility and metabolism. Huntsman Cancer Institute in an NCI-designated cancer center with state-of-the-art laboratories and shared resources\, including core facilities for imaging\, genomics\, drug screening\, and population studies. We offer a collegial and interactive research environment that fosters the development of junior faculty and robust graduate programs for training PhD and MD/PhD students. \nPlease apply at the following link: http://utah.peopleadmin.com/postings/67304 \nFor questions\, please contact Dee DalPonte at Dee.DalPonte@hci.utah.edu or (801)-585-7774.
URL:https://ces.b2sg.org/event/uofu-asstprof-aug17/
LOCATION:University of Utah\, 201 Presidents Cir\, Salt Lake City\, 84112\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170801
DTEND;VALUE=DATE:20170902
DTSTAMP:20170801T104350Z
CREATED:20170801T104350Z
LAST-MODIFIED:20170801T104350Z
UID:18921-1501545600-1504310399@ces.b2sg.org
SUMMARY:Computational Biologist I
DESCRIPTION:The core mission of the computational division of The Center for Epigenetics Research is to leverage genomic and epigenomic data to provide novel insights into cancer epigenetics\, and to communicate these results to multidisciplinary teams of basic and translational scientists\, clinicians\, and group leaders. This is accomplished through the integration of gene expression\, chromatin structure\, and sequence variation with clinical data and experimental animal models\, with the goal of understanding\, predicting\, and gaining therapeutic insight into the epigenetic components of tumorigenesis. \nThe bioinformatics scientist will be responsible for in depth integrative analysis of multiple genomic and epigenomic data types with a focus on advancing a systems level understanding of cancer epigenetics. He/she will also build analysis frameworks and statistical tools to be utilized more broadly across a range of project goals.  \nQualifications:  \n\nPh.D. or equivalent in bioinformatics\, computer science or related field. Ability to maintain detailed records of all analyses and to communicate findings in a clear and concise manner.\nDeep understanding of principles behind current genomic analysis methods\nResearch experience in computational biology\, with an emphasis on next-generation sequencing data\nExtensive experience with scientific computing (R or Matlab)\nProficient in scripting languages (Perl or Python)\nFamiliar with UNIX/Linux environment\nKnowledge of publicly available bioinformatics tools and software packages\nKnowledge of C\, C++\, or Java\nSolid understanding of probability and statistics\nExcellent verbal and written communication skills and ability to present analyses to a multi-disciplinary team of clinicians and scientists\n\n\n\n 
URL:https://ces.b2sg.org/event/msk-compbio-aug17/
LOCATION:Memorial Sloan Kettering\, 1275 York Avenue\, New York\, NY\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170730
DTEND;VALUE=DATE:20170805
DTSTAMP:20170509T085546Z
CREATED:20170507T213644Z
LAST-MODIFIED:20170509T085546Z
UID:17878-1501372800-1501891199@ces.b2sg.org
SUMMARY:Epigenetics in Action: From Mechanisms to Biological Impacts
DESCRIPTION:This meeting takes place in a relaxed environment with outstanding scientists at all post-undergraduate stages. In this informal atmosphere\, discussions begin over breakfast\, continue during the afternoon and extend into the evening through convivial gatherings after each session. Early career scientists and students will have the occasion to discuss their unpublished data with distinguished leaders throughout the conference\, and will have the opportunity to present their work in dedicated slots throughout the program.  \nFor the second time the conference will incorporate a Gordon Research Seminar as a specific means to foster involvement by scientists at the graduate student and post doctoral level. Planned by and for trainees\, it will provide an opportunity for our junior researchers to present seminars and posters in a supportive\, interactive environment. \nSpeakers: \nBradley Bernstein\, Harvard University\, USA \nWendy Bickmore\, MRC Human Genetics Unit\, United Kingdom \nXin Chen\, Johns Hopkins University\, USA \nVincent Colot\, Institut de Biologie de l’Ecole Normale Supérieure\, France \nCaroline Dean\, John Innes Centre\, United Kingdom \nJohn Denu\, University of Wisconsin-Madison\, USA \nInes Drinnenberg\, Institut Curie\, France \nSylvia Erhardt\, ZMBH\, Universität Heidelberg\, Germany \nAnne Ferguson-Smith\, University of Cambridge\, United Kingdom \nSusan Gasser\, Friedrich Miescher Institute for Biomedical Research\, Switzerland \nCharles Gersbach\, Duke University\, USA \nDavid Gilbert\, Florida State University\, USA \nJohn Greally\, Albert Einstein College of Medicine\, USA \nShiv Grewal National Institutes of Health\, USA \nAnja Groth\, Biotech Research and Innovation Centre (BRIC)\, University of Copenhagen\, Denmark \nEdith Heard\, Institut Curie\, France \nSteven Jacobsen\, University of California\, Los Angeles / Howard Hughes Medical Institute\, USA \nBenjamin Loppin\, Laboratoire de Biométrie et Biologie Évolutive\, University of Lyon\, France \nKeith Maggert\, University of Arizona\, USA \nHarmit Malik\, Fred Hutchinson Cancer Research Center\, USA \nRobert Martienssen\, Cold Spring Harbor Laboratory\, USA \nMarie Mirouze\, Institut de Recherche pour le Développement (IRD)\, France \nErik Miska\, University of Cambridge\, United Kingdom \nJuerg Mueller\, Max Planck Institute of Biochemistry\, Germany \nVardhman Rakyan\, Blizard Institute\, United Kingdom \nJohn Rinn\, Harvard University\, USA \nSusan Strome\, University of California\, Santa Cruz\, USA \nAzim Surani\, University of Cambridge\, United Kingdom \nMaria-Elena Torres-Padilla\, Institute of Epigenetics and Stem Cells\, Helmholtz Zentrum München\, Germany \nTing Wu\, Harvard Medical School\, USA \nThis GRC will be held in conjunction with the “Epigenetics” Gordon Research Seminar (GRS). Those interested in attending both meetings must submit an application for the GRS in addition to an application for the GRC. Refer to the associated GRS program page for more information.
URL:https://ces.b2sg.org/event/epigenetics-in-action-jul2017/
LOCATION:Holderness School\, 33 Chapel Ln\, Holderness\, NH\, 03245\, United States
CATEGORIES:Meetings
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170728
DTEND;VALUE=DATE:20170829
DTSTAMP:20170728T194415Z
CREATED:20170728T194415Z
LAST-MODIFIED:20170728T194415Z
UID:18907-1501200000-1503964799@ces.b2sg.org
SUMMARY:Senior Research Associate I
DESCRIPTION:The Sylvester Comprehensive Cancer Center is seeking a Sr. Research Associate. The incumbent performs laboratory assignments\, including the planning and conducting of projects related to cell culture and molecular biology. Schedule and perform experiments in research laboratory. Solve problems in scientific and technical execution\, interpret experimental data and maintain accurate records. Assist in the preparation of data and figures for manuscripts and for scientific presentations using Photoshop/Illustrator Adobe. Search literature for references to technical problems and keep informed by reading technical journal and publications. Present data in laboratory meetings and other venues. Ensure and document laboratory adherence to safety standards\, especially in the use of hazardous items. Assist with the implementation of new program and initiatives. Responsible for developing and preparing PowerPoint presentations. Assist in the review and preparation of manuscripts for submission to journals.Other duties as assigned. Job descriptions are not intended\, and should not be construed to be exhaustive lists of all responsibilities\, skills\, efforts or working conditions associated with a job.  Management reserves the right to revise duties as needed. Education & Experience: Master’s Degree required preferably\, with at least 2 years laboratory experience in a relevant discipline in cell/molecular biology\, pathology\, stem cell or breast/ovarian cancer research. Must have broad knowledge of carcinoma or related fields of cancer research as well as experience in human cell/tissue culture\, molecular biological techniques\, and experimental experience with animal models and studies in epigenetics.\nThe minimum qualifications are: Master’s degree required preferably\, with at least 2 years of laboratory experience in a relevant discipline in cell / molecular biology\, pathology\, stem cell or breast / ovarian cancer research. Must have broad knowledge of carcinoma or related fields of cancer research as well  as experience in human / cell tissue culture\, molecular biological techniques and experimental experience with animal models and studies in epigenetics. Ability to plan\, organize and meet deadline; highly motivated\, must be detail oriented\, self-starter with strong interpersonal skills.Knowledge of PC software programs: Word\, Excel\, and PowerPoint\, SPSS is an asset. Need the ability to manage multiple tasks simultaneously and independently.Must be able to apply logic and demonstrate problem-solving techniques. Any appropriate combination of relevant education\, experience and/or certifications may be considered.
URL:https://ces.b2sg.org/event/umiami-sr-res-jul17/
LOCATION:University of Miami\, 1320 S Dixie Hwy\, Coral Gables\, FL\, 33146\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170728
DTEND;VALUE=DATE:20170829
DTSTAMP:20170728T193341Z
CREATED:20170728T192654Z
LAST-MODIFIED:20170728T193341Z
UID:18904-1501200000-1503964799@ces.b2sg.org
SUMMARY:Post-Doctoral Research Fellow
DESCRIPTION:A postdoctoral research fellow position is available in the Bedalov Laboratory in the Clinical Research Division. The Bedalov laboratory studies mechanisms by which chromatin modifications shape nuclear events including DNA replication and transcriptional silencing and their consequences on carcinogenesis\, aging and development.  \n \n\n\n\nResponsibilities\n\n\n\nThe post-doctoral research fellow will study molecular mechanisms that maintain the silent state of the inactive X-chromosome in female cells and will devise genetic and pharmacologic strategies for reversing transcriptional silencing of genes on the inactive X-chromosome for therapeutic purposes in genetic diseases such as Rett Syndrome. Rett Syndrome is a neurodevelopmental disorder in females who are heterozygous for a mutation in the X-linked gene MeCP2. The candidate will employ cell culture and murine genetics to reactivate MeCP2 in the inactive X-chromosome. \n \n\n\n\nQualifications\n\n\n\nThe minimum requirements to be considered for this position are: \n\nA PhD in a related scientific field\nAdvanced knowledge of molecular biology techniques\, tissue culture\, and viral assays and a background in molecular/cell biology\, biochemistry\nPrior experience in epigenetics and mouse genetics is highly desirable\nMust be highly motivated and able to work independently in a large research group setting to design and execute experiments
URL:https://ces.b2sg.org/event/fred-hutch-postdoc-jul17/
LOCATION:Fred Hutchinson Cancer Research Center\, 1100 Fairview Ave. N.\, Seattle\, WA\, 98109-1024\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170728
DTEND;VALUE=DATE:20170829
DTSTAMP:20170728T174739Z
CREATED:20170728T174538Z
LAST-MODIFIED:20170728T174739Z
UID:18901-1501200000-1503964799@ces.b2sg.org
SUMMARY:Research Professional I
DESCRIPTION:The laboratory research focuses on understanding the role of various enzymes involved in human malignancies\, and development of anti-cancer drugs. The Research Professional 1 requires the ability to perform tasks with supervision. Collaborations with other laboratories and investigators within the Section and Department are routine. \nEssential Functions: \n1. 80% — Performing laboratory techniques; must have an experience of RNA-based TCR sequencing of cancer tissues\, isolation of tumor infiltrating T cells (TILs)\, and culture of TILs\n 2. 20% — Collate and analyze data. Maintain accurate\, up-to-date and well-documented records of procedures performed and data generated. Summarize results and assist in interpreting findings including analysis of DNA sequencing.   \nA doctoral degree in Cancer Biology\, Immunology\, Molecular Genetics\, Cell Biology\, Medical Technology\, Biochemistry or related discipline is required.   \n5 years of experience for cancer genetics and biology with some publications is required. Previous cell culture and clinical laboratory experience is essential. Excellent organizational\, interpersonal and communication skills are essential. Experiences in urological cancers are preferable.   \nAdvanced knowledge in relevant scientific field required.\nAdvanced knowledge of research techniques or methods required.\nKnowledge of regulatory policies and procedures required.\nAnalytical skills required.\nProblem-solving skills required.\nAttention to detail required.\nOrganizational skills required.\nVerbal and written communication skills required.\nAbility to work independently and as part of a team\nrequired.\nKnowledge of Microsoft Office required.  
URL:https://ces.b2sg.org/event/uchicago-research-pro/
LOCATION:University of Chicago\, 5801 S Ellis Ave\, Chicago\, IL\, 60637\, United States
CATEGORIES:Jobs
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20170728
DTEND;VALUE=DATE:20170829
DTSTAMP:20170728T172858Z
CREATED:20170728T172519Z
LAST-MODIFIED:20170728T172858Z
UID:18896-1501200000-1503964799@ces.b2sg.org
SUMMARY:Research Specialist A
DESCRIPTION:Research Specialist position to aid an Instructor in the Division of Gastroenterology in the performance of experiments in a Cancer Biology laboratory aimed at studying the novel functions of epigenetic regulators in colon cancer and neuroendocrine tumors. The position will involve work with both cell culture experiments as well as some work with mouse models. Cell culture based responsibilities will include maintaining and passaging cell lines\, treating cells with drugs\, transfections\, plasmid preparation\, and analysis of cell-based experiments with RT-PCR and western blotting. Mouse responsibilities may include animal husbandry\, genotyping\, oral gavage\, xenograft monitoring\, as well as tissue processing including isolation and embedding of mouse organs/tumors for sectioning and staining. \nA Bachelor’s Degree and 0 to 1 year of experience or equivalent combination of education and experience is required. Experience in some laboratory based procedures including work with cell culture and/or mouse models is preferred. The candidate must also possess strong communication and organizational skills as well as basic computer skills.
URL:https://ces.b2sg.org/event/upenn-res-specialist-a/
LOCATION:University of Pennsylvania\, 3400 Civic Center Blvd\, Philadelphia\, 19104\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/05/penn-1-e1494306554396.jpg
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20170727
DTEND;VALUE=DATE:20170828
DTSTAMP:20170727T195627Z
CREATED:20170727T195524Z
LAST-MODIFIED:20170727T195627Z
UID:18893-1501113600-1503878399@ces.b2sg.org
SUMMARY:Postdoctoral Scholar
DESCRIPTION:We are seeking a highly motivated Postdoctoral Scholar to move our research forward. The Sherman Lab aims to understand the transcriptional and epigenetic gene-regulatory networks that underlie tumor-stroma interactions in pancreatic cancer\, and to target these networks for therapeutic benefit.  Our research focuses on the mechanisms by which stromal fibroblasts in the pancreatic tumor microenvironment influence cancer cell gene expression\, metabolism\, and growth.  Our laboratory uses a multidisciplinary approach to investigate the mechanistic underpinnings of the pancreatic tumor microenvironment\, including mouse models of pancreatic cancer\, three-dimensional cell culture systems such as patient-derived organoids\, and diverse molecular- and cell-biological techniques focused on gene regulation.  \nThe ideal candidate for this position will be highly interactive\, but capable of working independently on research focused on tumor-permissive molecular mechanisms underlying cancer-associated fibroblast function\, and how these stromal mechanisms affect cell fate and function in the pancreatic epithelium. \nIdeal candidates should have no more than 1 year of postdoctoral experience\, and are expected to compete for internal and external funding. Highly motivated candidates should upload a cover letter describing your relevant qualifications\, future interests\, and expected start date; CV; and names and contact information for three references. \n\n\n\nRequired: \n\nPh.D. or M.D./Ph.D.\, in related field of study\nExcellent written and verbal communication skills.\nExperience with model organisms\, cell culture\, functional analyses (proliferation/apoptosis assays\, Western blot\, real-time qPCR\, etc.)\, and molecular cloning is required\n\nPreferred: \n\nFirst authorship on at least one paper in a peer-reviewed English language journal.\nExperience in mouse models of cancer and high-throughput sequencing preferred.
URL:https://ces.b2sg.org/event/ohsu-postdoc-scholar/
LOCATION:OHSU\, 3181 SW Sam Jackson Park Rd\, Portland\, OR\, 97239\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170727
DTEND;VALUE=DATE:20170828
DTSTAMP:20170727T194501Z
CREATED:20170727T194501Z
LAST-MODIFIED:20170727T194501Z
UID:18889-1501113600-1503878399@ces.b2sg.org
SUMMARY:Postdoctoral Fellow
DESCRIPTION:A Post Doctoral position is available in the Villanueva Lab at the Wistar Institute to study mechanisms of therapy resistance using genetic and biochemical approaches.  We are seeking a highly-motivated candidate who can integrate new concepts and techniques to investigate mechanisms of drug resistance and identify new therapeutic targets.    \n\nApplicants must be recent graduates with proven expertise in molecular biology and transcriptional regulation. Experience and/or interest in immunology\, epigenetics and mouse models is desired.  Candidates must have achieved academic excellence and be creative thinkers with strong record of productivity.  Excellent communication and organizational skills are required.   Interested candidates should submit summary of research experience and scientific interests\, CV\, and names and contact information of 3 references. \n\nThe Wistar Institute is located in the University City area of Philadelphia\, in the heart of the University of Pennsylvania Campus. Wistar provides resources to its faculty and staff that enable them to conduct cutting edge collaborative research and provides for outstanding intellectual environments and state-of-the-art facilities. Research discoveries conducted at Wistar have led to the development of vaccines; the identification of genes associated with cancers; and the development of many other significant research technologies and tools. \nWe offer an excellent benefits package.\nFor more information about The Wistar Institute visit our website at www.wistar.org.
URL:https://ces.b2sg.org/event/wistar-postdoc/
LOCATION:Wistar Institute\, 3601 Spruce Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170727
DTEND;VALUE=DATE:20170828
DTSTAMP:20170727T193507Z
CREATED:20170727T193431Z
LAST-MODIFIED:20170727T193507Z
UID:18884-1501113600-1503878399@ces.b2sg.org
SUMMARY:Project Scientist
DESCRIPTION:The Project Scientist works independently and in cooperation with the Principal Investigator to make significant and creative contributions to a research or creative project in any academic discipline. The Project Scientist may be an ongoing member of a research team or may be employed for a limited period of time to contribute high-level skills to a specific research or creative program. Project Scientists are not required to carry out independent research or to develop an independent research reputation and do not have teaching responsibilities. Ordinarily\, the Project Scientist title will carry out research or creative programs as well as administration of day-to-day lab operations with supervision by a member of the Professorial Series.  \nDr. Megan Hitchins Laboratory specific –  \nESSENTIAL JOB RESPONSIBILITIES:\nOrdering and maintaining laboratory supplies\nMaintenance of chemical inventory and sample database\nSafe handling and processing of human blood\, saliva\, semen\, formalin fixed paraffin embedded (FFPE) tissue blocks\, and other clinical samples\nConduct genetic\, epigenetic\, and other molecular biology protocols accurately and reproducibly to generate original data from a high volume of samples\nDealing with high volumes of biospecimens and interfacing with the biorepositories and core facilities\nPerform raw data analyses for genetic and epigenetic variation\nDraft sections of manuscripts or figures for publication in scientific journals and/or grant applications \nEducational Requirements:\nM.D. or Ph.D or highest degree in their field.\nDemonstrated significant\, original\, and creative contributions to a research or creative program or project\nin area of specialization\, as applicable. \nLicense/Certification/Registration Requirements:\nThe following certifications of training will need to be completed and maintained:\nCITI Institutional Review Board training in research involving human subjects\nTraining in the safe handling of biological and hazardous substances\nDepartment of Transport training in the shipment of hazardous substances\nHIPAA training for protection of human subjects \nExperience:\nCompletion of postdoctoral appointment or extensive experience in the area of cancer genetics\, epigenetics\, and/or molecular biology. Knowledge of cancer genetics\, epigenetics\, and/or molecular epidemiology. Demonstrated technical competency in a variety of research techniques and protocols pertaining to the analyses of genetic and epigenetic variation and gene expression states. Experience handling large sample volumes and database. \nFamiliarity with\, or ability to rapidly learn\, the following wet-laboratory techniques: Sterile cell culture and cryopreservation; Microdissection of formalin-fixed paraffin embedded (FFPE) samples of tumor blocks; Sectioning of tumor blocks; generation of tissue microarrays; DNA and RNA extractions from fresh\, frozen\, and FFPE tissues; cDNA synthesis and reverse transcriptase PCR; PCR and real-time PCR; Generation of libraries for whole genome sequencing and whole genome bisulfite sequencing; Cloning and culture of bacterial colonies containing recombinant DNA; Gel electrophoresis; Western blotting; Pyrosequencing; Sodium bisulfite conversion of genomic DNA for methylation analyses. Familiarity with Microsoft Office\, Adobe Illustrator\, DNA sequence analysis and alignment programs (e.g. DNAStar\, BLAT\, BLAST)\, primer design software \nPhysical Demands:\nAble to sit for moderate periods of time. Able to use a computer workstation for moderate periods of time. Able to sit\, stand and walk for prolonged periods of time. Able to read papers online and documents. Able to operate standard office equipment. Able to exercise physical ability and perspective acuity to satisfactorily perform essential job functions
URL:https://ces.b2sg.org/event/cedars-sinai-proj-sci/
LOCATION:Cedars-Sinai Medical Center\, Los Angeles\, 8700 Beverly Blvd\, Los Angeles\, CA\, 90048\, United States
CATEGORIES:Jobs
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END:VCALENDAR