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X-WR-CALDESC:Events for Cancer Epigenetics Society
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DTSTART;VALUE=DATE:20171231
DTEND;VALUE=DATE:20180203
DTSTAMP:20171231T172321Z
CREATED:20171231T172321Z
LAST-MODIFIED:20171231T172321Z
UID:19562-1514678400-1517615999@ces.b2sg.org
SUMMARY:Assistant/ Associate/ Full Professor
DESCRIPTION:The Department of Cancer Biology at The University of Texas MD Anderson Cancer Center invites applicants for a full-time term tenure track academic appointment at the level of Assistant\, Associate\, or Full Professor. We seek exceptional scientists or physician scientists with demonstrated dedication to solving fundamental questions about the origin\, progression\, dissemination\, and resistance to therapy of cancer as well as basic scientists working on fundamental processes relevant to cancer. The successful applicant will develop a hypothesis-driven basic and translational research program in the field of general biology\, cancer pathogenesis\, cancer biology\, or cancer genetics. Preference will be given to candidates committed to conduct mechanistic studies by employing a variety of approaches\, ranging from genomics\, mouse modeling\, and biochemistry to high-resolution in vivo imaging. A secondary appointment in an appropriate clinical or basic science department will be considered. Areas of interest include – but are not limited to – epigenetics\, cell fate determination\, structural biology\, tumor microenvironment and cell signaling. \nThe position offers enormous opportunities for professional growth and development. The successful candidate will join an exciting and active group of investigators\, including Ron DePinho\, Filippo Giancotti\, Jian Hu\, Raghu Kalluri\, Valerie LeBleu\, Randy Johnson\, Katharina Schlacher\, and among others. The joint faculty of the department include James P. Allison\, David Piwnica-Worms\, John Tainer and others. The faculty member will have access to the department’s substantial resources\, including cutting edge core facilities\, animal models\, and educational/training programs. A very generous start-up package is available for the Faculty member’s research program; furthermore\, it is anticipated that successful candidates will have the scientific caliber and accomplishments to compete successfully for a Recruitment Award from the Cancer Research and Prevention Institute of Texas (CPRIT) and The University of Texas Regents Funding. Refer to the Department of Cancer Biology Web page for additional information about the department and its programs.
URL:https://ces.b2sg.org/event/mdanderson-31dec17/
LOCATION:MD Anderson Cancer Center\, 1515 Holcombe Blvd\, Houston\, TX\, 77030\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20171231
DTEND;VALUE=DATE:20180301
DTSTAMP:20171231T173056Z
CREATED:20171231T173056Z
LAST-MODIFIED:20171231T173056Z
UID:19564-1514678400-1519862399@ces.b2sg.org
SUMMARY:Assistant/Associate Professor
DESCRIPTION:The Department of Pathology and Laboratory Medicine at the Perelman School of Medicine at the University of Pennsylvania seeks candidates for an Associate or Assistant Professor position in the tenure track. The successful applicant will have experience in the field of Genome Editing & Functional Cancer Genomics and will creatively leverage the CRISPR/Cas9 or similar technologies towards functional characterization of chromosomal translocations\, candidate drive mutations\, epigenetic alterations\, genetic polymorphisms\, etc. Identification of new susceptibility alleles in important pediatric cancers and related diseases is also a priority. Responsibilities include establishing and maintaining an independent\, extramurally funded research program. Teaching and mentoring of graduate and medical students is an integral component of this position. Applicants must have an M.D./Ph.D or equivalent degree and have demonstrated excellent qualifications in research and education. \nThe position is affiliated with the Division of Cancer Pathobiology & the Center for Childhood Cancer Research at the Children’s Hospital of Philadelphia (CHOP). The Division & CCCR are housed in the state-of-the-art Colket Translational Research Building. More information about the program can be found at: http://www.chop.edu/cccr/research-topic/cancer-pathobiology-research 
URL:https://ces.b2sg.org/event/upenn-31dec17/
LOCATION:University of Pennsylvania\, 3400 Civic Center Blvd\, Philadelphia\, 19104\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20171231
DTEND;VALUE=DATE:20180203
DTSTAMP:20171231T174008Z
CREATED:20171231T173901Z
LAST-MODIFIED:20171231T174008Z
UID:19568-1514678400-1517615999@ces.b2sg.org
SUMMARY:Senior Research Worker
DESCRIPTION:A Senior Research Worker is available in Dr. Chao Lu’s lab investigating molecular mechanisms of chromatin and epigenetic regulation and its implications for human cancer. The senior research worker will serve as a lab manager in charge of ordering supplies\, maintaining lab stocks and maintaining transgenic mouse breeding colonies\, including genotyping and husbandry. He/she will also supervise and perform molecular and cell biology experiments\, epigenetic assays\, and tissue histology/imaging. The candidate will be responsible for data collection and computer entry and will carry out research projects under supervision. We offer competitive salary. To learn more about the research laboratory. please visit: www.chaolulab.com. \nMinimum Qualifications for Grade\n Applicant MUST meet these minimum qualifications to be considered an applicant \nMaster’s degree and at least three years experience\, or Bachelor’s degree and at least five years of related experience or equivalent in education\, training\, and experience. 
URL:https://ces.b2sg.org/event/columbia-31dec17/
LOCATION:Columbia University Medical Center\, 630 W 168th St\, New York\, NY\, 10032\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20171231
DTEND;VALUE=DATE:20180203
DTSTAMP:20171231T175248Z
CREATED:20171231T175248Z
LAST-MODIFIED:20171231T175248Z
UID:19571-1514678400-1517615999@ces.b2sg.org
SUMMARY:Translational Research Project Leader
DESCRIPTION:We are looking to add an integral member to our team who will join a fast-paced department and be able to juggle multiple and evolving priorities. \nWe are a small\, agile\, and cross-functional team – so we need a dynamic self-starter to hit the ground running and work well in a fluid\, collaborative setting! \nAs a Translational Research Project Leader on our team\, you will be responsible for managing and overseeing clinical trial correlative research projects. We currently are involved in six ongoing multi-institutional early phase trials involving epigenetics agents used in combination in hematologic and solid tumor malignancies with robust correlative research efforts. All of these trials are conducted in partnership with our member institutions\, including Fox Chase\, Johns Hopkins\, Memorial Sloan Kettering\, University of Copenhagen/Rigshospitalet\, University of Southern California\, University of Maryland\, and Temple University. Additionally\, we rely and value our rich partnerships with the pharmaceutical industry. Learn more about VARI-SU2C here. \nDuties include\, but not limited to: \nManaging Correlative Research Projects \n\nPlan\, coordinate\, and oversee the execution of correlative research coordinated by VARI for the VARI-SU2C program.\nIn a customer service-oriented manner discuss the plans for correlative research\, data analysis\, and deliverables with the clinical trial PIs\, consortium members\, VARI investigators and research staff\, and collaborators.\nCoordinate the development and implementation of correlative research SOPs including raw assay analyses\, data upload\, data storage\, genomic data storage\, clinical data coding/de-identification\, etc.\n\nBioinformatics & Data Management \n\nOversee the development of data hub for VARI-SU2C consortium.\nInterpret bioinformatics data.\nOversee database and report setup\, as well as processing and cleaning correlative research data\, following all applicable standard and study-specific procedures.\n\n\nThe Education and Skills We Expect You to Possess: \n\n\nA Ph.D. or M.S. degree in life science or computer science\, with a degree in computational biology preferred.\n3 -5 years of experience of translational research experience\, specifically related in genetic and epigenetic sequencing assays\nPrevious data analysis project management leadership experience.\nDemonstrated knowledge of command line bioinformatics software and basic knowledge of data pipelines. Knowledge of database design (e.g.\, SQL\, Access\, etc.).\nExcellent verbal and written communication and interpersonal skills and significant customer service background and skills.
URL:https://ces.b2sg.org/event/vari-31dec17/
LOCATION:Van Andel Research Insitute\, Grand Rapis\, MI\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180102
DTEND;VALUE=DATE:20180204
DTSTAMP:20180102T193149Z
CREATED:20180102T192915Z
LAST-MODIFIED:20180102T193149Z
UID:19578-1514851200-1517702399@ces.b2sg.org
SUMMARY:Postdoctoral Fellow
DESCRIPTION:Postdoc Positions Focusing on Gene Regulation in Cancer Progression \nMultiple postdoctoral positions are available in the laboratory of Dr. Jason Liu (http://molecularmedicine.uthscsa.edu/FAC_Research.aspx?facID=206) in the Department of Molecular Medicine at the University of Texas Health Science Center at San Antonio \nThe focus of the lab is studying enhancer function and epigenetic mechanism in gene regulation in cancer progression. Selected candidates will perform highly interdisciplinary and collaborative scientific research in one or more of the following projects\, working with human cell lines\, mouse models and clinical samples: \n(1) Explore the function of signaling-regulated enhancers in breast and prostate cancers\, and understand how enhancers are regulated by the crosstalk of different signaling pathways including sex hormones\, inflammation signals and metabolic signals; \n(2) Decipher the epigenetic and chromatin 3D level changes in enhancers upon developmental/pathological stimuli or during hormone/drug resistance acquisition; \n(3) Identify diagnostic/prognostic biomarkers and therapeutic targets for cancer and develop drugs for pre-clinical studies and potential clinical applications. \nOur research integrates next-generation sequencing (NGS)-based technologies and bioinformatics tools to investigate the component\, epigenetic\, and 3D level changes of enhancers in cancers \n(refer to Cell\, 2014 159: 358–373). We are efficiently combining biochemical\, cellular\, and animal model-related studies with different NGS-based assays. Our research program will help the trainees from both wet and dry lab sides to build up strong expertise and training record in molecular biology and multi-omics (genomics\, transcriptomics\, proteomics\, epigenomics and metabolomics). \nPositions require a Ph.D. degree (or equivalent) in biochemistry\, cell biology\, cancer biology\, bioinformatics\, or closely related biological sciences. The candidates need to have high motivation and strong molecular biology background. Any prior experience in patient-derived xenograft (PDX) models\, breast/prostate cancer\, and computational analyses will be valued. \nSan Antonio is one of the fastest growing cities. The UTHSCSA is the largest university of health science in South Texas and one of four medical schools in the UT System. The affiliated Cancer Therapy & Research Center (CTRC) is one of the NCI-designated national cancer centers in the state of Texas. A competitive salary and benefits package will be provided. \nTo apply: \nPlease send the application package in one single pdf file including a cover letter briefly describing your previous experience and your future research interest/plan\, curriculum vitae with list of publications\, and contact information of at least three references to the following email. You are also welcome to send any inquiries or questions you might have. \nContact information: \nDr. Jason Liu \nDepartment of Molecular Medicine \nThe University of Texas Health Science Center at San Antonio \n7703 Floyd Curl Drive \nSan Antonio\, TX\, 78229-3900 \nEmail: LiuZ7@uthscsa.edu
URL:https://ces.b2sg.org/event/uthscsa-2feb18/
LOCATION:UT Health Science Center in San Antonio\, 7703 Floyd Curl Drive\, San Antonio\, TX\, 78229\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180103
DTEND;VALUE=DATE:20180205
DTSTAMP:20180103T173456Z
CREATED:20180103T173456Z
LAST-MODIFIED:20180103T173456Z
UID:19584-1514937600-1517788799@ces.b2sg.org
SUMMARY:Postdoctoral Fellow
DESCRIPTION:A postdoctoral position is available to work at the interface of cancer epigenetics and translational therapeutics for head and neck malignancies. The position will be supported by a new NIH R01 award and industry-sponsored agreements in the Division of Head and Neck Surgery at the University of Pennsylvania Perelman School of Medicine. Our research program aims to develop novel approaches to target the tumor cell fractions within individual cancers that are innately resistant to current therapies. Studies will emphasize molecular and functional definition of the epigenetically distinct cell states within a heterogeneous tumor that contribute to treatment failure. Work will rely upon advanced in vitro cancer models\, patient-derived xenografts\, and human tumor specimens. Significant prior experience in epigenetics\, cancer biology\, bioinformatics\, stem cell biology\, and/or biochemistry is desirable. Training and career development will also be supported by investigators in a P01-funded program in esophageal squamous cell carcinoma in the Division of Gastroenterology. Applicants authorized for employment in the United States are strongly preferred. However visa sponsorship may be considered for an exceptional foreign applicant with well-developed English writing ability. Interested individuals should send cover letter\, CV\, and detailed reference information\, including most recent research supervisor\, by e-mail to: \nDevraj Basu\, M.D\, Ph.D.\, F.A.C.S.\nAssistant Professor \nDepartment of Otorhinolaryngology-Head and Neck Surgery \nThe University of Pennsylvania\n3600 Spruce St.\, 5 Ravdin/Silverstein \nPhiladelphia\, PA 19104 \nemail: devraj.basu@uphs.upenn.edu \nhttp://www.med.upenn.edu/apps/faculty/index.php/g275/p8137952
URL:https://ces.b2sg.org/event/upenn-3jan18/
LOCATION:University of Pennsylvania\, 3400 Civic Center Blvd\, Philadelphia\, 19104\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180103
DTEND;VALUE=DATE:20180205
DTSTAMP:20180103T174237Z
CREATED:20180103T174123Z
LAST-MODIFIED:20180103T174237Z
UID:19587-1514937600-1517788799@ces.b2sg.org
SUMMARY:Postdoctoral Associate
DESCRIPTION:A postdoctoral position is immediately available in the EpiCenter in the Department of Pediatrics at Baylor College of Medicine in Houston\, Texas. The research will focus on determining the molecular mechanisms underlying adverse pediatric outcomes. The successful candidate will employ integrative molecular epidemiologic methods for the assessments of adverse pediatric outcomes\, including structural birth defects and childhood cancer. The individual will work with genetic\, epigenetic\, and metabolomic data. The goal of this work will be to identify novel molecular predictors of adverse pediatric outcomes. The candidate will also be involved in the EpiCenter’s growing activities in global health. Successful candidates will be expected to tackle challenging scientific problems\, develop and optimize epidemiologic analytic pipelines\, and contribute to the positive and energetic work environment of the EpiCenter. \nRequired: \n\nPhD in Epidemiology
URL:https://ces.b2sg.org/event/baylor-3jan18/
LOCATION:Baylor College of Medicine\, 1 Baylor Plaza\, Houston\, TX\, 77030\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180103
DTEND;VALUE=DATE:20180205
DTSTAMP:20180103T175322Z
CREATED:20180103T175322Z
LAST-MODIFIED:20180103T175322Z
UID:19589-1514937600-1517788799@ces.b2sg.org
SUMMARY:Postdoc
DESCRIPTION:A postdoctoral position is immediately available within the Masri Lab at the University of California\, Irvine (UC Irvine). The Masri lab employs a systemic approach to understanding cancer metabolism that is linked to the circadian clock\, the biological pacemaker that regulates diurnal physiology. We are interested in two research questions. The first question relates to how genetic disruption of the circadian clock in mouse models alters tumorigenesis both at the level of initiation and disease progression. The second question is aimed at elucidating the systemic crosstalk between tumors and peripheral tissues and how cancer cells are able to rewire circadian metabolism at a distance.  \nWe are seeking independent and motivated postdoctoral candidates interested in a multi-disciplinary approach to tumorigenesis including: cancer metabolism\, circadian clock disruption\, and transcription and epigenetic control. The Masri lab utilizes genetic mouse models\, molecular and cell biology\, as well as genome-wide ‘omics’ approaches to determine changes in gene expression programs\, histone modifications\, and alterations in metabolites using metabolomics. In addition\, bioinformatics expertise is an advantage\, but certainly not required. Experience with mouse handling and experiments\, mammalian cell culture\, and routine molecular and cell biology are needed. Also\, at least 1 first author publication from the Ph.D. training period is required.  \nFor consideration\, applicants may send an email to Professor Selma Masri ( Masrilaboratory@gmail.com) with the following information:  \n\nBrief statement of research interests and future goals\nCV detailing research experience\, publications\, any fellowships obtained during the training period\, and other relevant information\nList of any manuscripts in preparation or currently under review\nNames of 3 references that are familiar with the research experience of the candidate and can provide letters of recommendation upon request
URL:https://ces.b2sg.org/event/ucirvine-3jan18/
LOCATION:UC Irvine\, Irvine\, CA\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180104
DTEND;VALUE=DATE:20180207
DTSTAMP:20180104T223049Z
CREATED:20180104T223049Z
LAST-MODIFIED:20180104T223049Z
UID:19594-1515024000-1517961599@ces.b2sg.org
SUMMARY:Scientist - Computational Biology
DESCRIPTION:Client Quanticel Research\, a drug division of Client Pharmaceuticals\, is committed to the development of breakthrough medicines for the treatment of cancer. Our proprietary platform for single-cell analysis of the cancer genome enables the discovery of first-in-class oncology therapeutics.  \nCQR seeks a scientist to join our vibrant interdisciplinary team to develop and facilitate interpretation of complex next-generation sequencing data from tumor xenografts and derived single-cells. The right candidate will share our passion for pioneering new solutions\, continual improvement\, and uncompromising quality in research.  \nResponsibilities will include\, but are not limited to\, the following:  \n\nAdapt open source tools and/or develop visualization methods to enable bench scientists to query\, display and interpret NGS data types. These include RNA-expression from single-cells and bulk tissues\, variant data from exome sequencing\, copy-number data from whole genome sequencing\, and epigenetic data.\nFacilitate data sharing/management from internal and open-source based databases.\nAbility to integrate laboratory instrument metadata to databases\n\nSkills/Knowledge Required: \n\nProficiency in shell scripting\, Django/Python\, R/Shiny\, SQL and JavaScript. Java considered a plus.\nComfortable working in Linux and Docker environments.\nGeneral knowledge of NGS technologies\, sequence analysis tools and public visualization resources.\nExperience with Amazon EC2 cloud resources; e.g. S3\, EC2\, Lambda and others.\nHighly self-motivated and enjoy working as part of a multi-disciplinary team\nOutstanding oral and written communication skills\n\nFunctional/Scientific/Technical Skills: \n\nAble to critically structure data.\nPossess in-depth knowledge in some area of data visualization\nUnderstands fundamental scientific problems and can apply knowledge to research and development projects and problems in a positive manner.\nContributes individually as well as on cross functional teams.\nResponsible for more complex assignments and for more than one project.
URL:https://ces.b2sg.org/event/advent-4jan18/
LOCATION:Advent Global Solutions\, San Francisco\, CA\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180104
DTEND;VALUE=DATE:20180207
DTSTAMP:20180104T224017Z
CREATED:20180104T223924Z
LAST-MODIFIED:20180104T224017Z
UID:19598-1515024000-1517961599@ces.b2sg.org
SUMMARY:Research Assistant
DESCRIPTION:The Wistar Institute has an opening for a Research Assistant in the laboratory of Dr. Rugang Zhang to perform research in which explores epigenetic approaches to ovarian cancer using tissue culture and patient-derived xenograft models.  \nThe candidate will work on a project sponsored by a pharmaceutical company to explore epigenetic therapy in ovarian cancer. The candidate will have ample opportunity to learn cutting-edge experimental techniques and clinically relevant preclinical ovarian cancer models. Duties include\, but are not limited to\, experiments in molecular biology\, cell biology\, tissue culture and mouse models of ovarian cancer.  \nBS/BA in biology or related field. Experience working in a lab is desirable but not required.  \nThe Wistar Institute is located in the University City area of Philadelphia\, in the heart of the University of Pennsylvania Campus. Wistar provides resources to its faculty and staff that enable them to conduct cutting edge collaborative research and provides for outstanding intellectual environments and state-of-the-art facilities. Research discoveries conducted at Wistar have led to the development of vaccines; the identification of genes associated with cancers; and the development of many other significant research technologies and tools. 
URL:https://ces.b2sg.org/event/wistar-4dec18/
LOCATION:Wistar Institute\, 3601 Spruce Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180114
DTEND;VALUE=DATE:20180216
DTSTAMP:20180114T165829Z
CREATED:20180114T165829Z
LAST-MODIFIED:20180114T165829Z
UID:19606-1515888000-1518739199@ces.b2sg.org
SUMMARY:Postdoctoral Scientist
DESCRIPTION:The Biochemistry and Molecular Medicine department is looking for a candidate that will work under the direct supervision of Dr. Mei-Yi Wu. He or she will be responsible for carrying out the research experiments. He or she will also participate in the weekly lab meeting\, and present and discuss the progress of the project with Dr. Mei-Yi Wu.  \nThe project focuses on two epigenetic modulators and members of the AT-rich interaction domain family\, ARID4A and ARID4B. Epigenetics plays an important role in human health and disease. Disruption of epigenetic modifications leads to dysregulation of gene function without altering the DNA sequence per se. A major challenge in understanding the importance of epigenetics in human health and diseases is to identify the specific epigenetic factors and the signaling involved. Currently\, we are investigating the role of ARID4A and ARID4B in development and cancer disease using state-of-the-art conditional knockout mouse models and genomic and proteomic approach. We also study the role of ARID4B in cancer stem cells that have been suggested as the major cause for therapy resistance and the driving force behind cancer metastasis and relapse. To investigate whether and how ARID4B drive cancer development\, we evalute the underlying molecular mechanisms by which ARID4B promotes therapy resistance and aggressive cancer.  \nDuties include: \n-Culture and transfection of mammial cells \n-Collecting samples for reporter gene assays \n-Western blooting to analyze protein expression \n-Cancer cell migration and invasion assays \n-Human cancer xenogrant experiments using SCID / NOD mice \n-The postdoc will also work with genetically modified mice \n-Ordering lab supplies\, lab maintenance and other duties as assigned \n-This position performs other duties as assigned. The omission of specific duties does not preclude the supervisor from assigning duties that are logically related to the position.  \nMinimum Qualifications: \nQualified candidates will hold a PhD in a related discipline. Degree must be conferred by the start date of the position  \nAdditional Required Licenses/Certifications/Posting Specific Minimum Qualifications:  \nPreferred Qualifications: \nPh.D. degree\, with experience in molecular and cellular biology. 
URL:https://ces.b2sg.org/event/gwu-14jan18/
LOCATION:George Washington University\, 2121 I St NW\, Washington\, DC\, 20052\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180114
DTEND;VALUE=DATE:20180216
DTSTAMP:20180114T171008Z
CREATED:20180114T170932Z
LAST-MODIFIED:20180114T171008Z
UID:19608-1515888000-1518739199@ces.b2sg.org
SUMMARY:Research Scientist
DESCRIPTION:RESEARCH SCIENTIST\, Koch Institute (KI) for Integrative Cancer Research-J&J Lung Cancer Initiative Collaboration (multiple positions)\, to contribute to three KI laboratories involved in research regarding the discovery and development of therapeutics and diagnostics that may be useful treating\, preventing\, intercepting\, and/or diagnosing diseases specifically focused on lung cancer. The Jacks Laboratory will focus on genetic and epigenetic changes accompanying and controlling lung cancer initiation and progression; developing vaccines for disease interception; and the role of inflammation\, inflammatory cells\, and specific inflammatory mediators in lung cancer development. The Bhatia Laboratory will focus on novel diagnostic and early detection technologies\, including protease activity-based nanosensors and explore the utility of these technologies using human genomic data and genetically-engineered mouse models (GEMMs) of lung cancer to detect and stratify disease early enough for interception. The Irvine laboratory will focus on early interception using immunotherapy agents to detect and prophylactically protect from lung cancer and generate novel immune-based drugs and vaccine platforms\, especially focused on Kras-mutant lung tumors. These will be tested initially in GEMM models. Will contribute to executing research aims; establishing research strategy; reporting; and planning and writing animal and other protocols\, manuscripts\, and reports.  \nJob Requirements: \nREQUIRED: MD and/or Ph.D. in medicine and/or biomedical science; extensive knowledge of cancer biology and related fields; ability to conceptualize and write proposals and publishable manuscripts\, evaluate and train junior researchers\, innovate\, and conduct research; meticulous attention to detail; strong organizational\, documentation\, interpersonal\, and communication skills; comfort summarizing and reporting results; ability to work collaboratively\, follow safety procedures\, and maintain a safe work environment. Familiarity with physiology; cell and molecular biology; immunology; animal testing of biologics; materials science; and/or histological\, biochemical\, and mechanical analyses ideal. Job #15547  \nThis is a one-year\, term-limit appointment with an extension based on continued funding.
URL:https://ces.b2sg.org/event/mit-14jan18/
LOCATION:Koch Institute MIT\, Cambridge\, MA\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180114
DTEND;VALUE=DATE:20180216
DTSTAMP:20180114T213910Z
CREATED:20180114T213848Z
LAST-MODIFIED:20180114T213910Z
UID:19614-1515888000-1518739199@ces.b2sg.org
SUMMARY:Postdoctoral Associate
DESCRIPTION:Applications are invited from ambitious\, independent and motivated candidates to work with Professor Peter D. Adams to investigate the epigenetics of aging and cancer at Sanford Burnham Prebys Medical Discovery Institute\, San Diego. Specific projects in the lab range from development of novel epigenetic therapies to combat cancer (for example\, epigenetic therapies to synergize with immune therapies)\, to investigation of epigenetic mechanisms that contribute to age-associated increase in cancer. A long-term goal of the lab is to develop epigenetic-based approaches for cancer chemoprevention.  \nThe project will employ state-of-the-art molecular and cellular biology approaches\, including ChIP-seq\, RNA-seq\, ATAC-seq\, DNA methyl-seq and other large-scale epigenomic and chromatin analyses\, including at the single-cell level; high throughput chemical and RNAi/CRISPR phenotypic screens; cell imaging; state-of-the-art gene manipulations using RNAi and CRISPR technology. In addition\, we routinely employ sophisticated mouse models and human tissues.  \nThe lab strives to be highly collaborative with other labs in San Diego\, the US and elsewhere\, for example collaborating with computational biologists\, immunologists\, experts in specific mouse models of cancer and aging\, and surgeons\, pathologists and clinical oncologists. San Diego is an outstanding scientific environment and a fabulous place to live.  \nRequired Skills  \nRequired Experience  \nCandidates should have\, or be working towards\, a PhD or equivalent degree in a biological science. Expertise in an aspect of cell and/or molecular biology and/or animal models is essential. The lab has dedicated computational biology support for data analysis\, so computational expertise is an advantage\, but not essential. Successful applicants will be able to learn computational approaches for analysis of large datasets\, a big advantage in a competitive job market.  \nInterested candidates should submit one PDF with a summary of achievements and research interests\, updated CV and contact information for 3 letters of references.  \nLab website: https://chromatin.wordpress.com 
URL:https://ces.b2sg.org/event/sbp-14jan18/
LOCATION:Sanford Burnham Prebys Medical Discovery Institute\, 10901 N Torrey Pines Rd\, La Jolla\, CA\, 92037\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/06/sanford-burham-sbp.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180119
DTEND;VALUE=DATE:20180221
DTSTAMP:20180120T035022Z
CREATED:20180120T034721Z
LAST-MODIFIED:20180120T035022Z
UID:19620-1516320000-1519171199@ces.b2sg.org
SUMMARY:Intern - Molecular Oncology
DESCRIPTION:Start Date: Summer 2018  \nLength of Assignment: 12 weeks  \nThe mission of the Molecular Oncology department is to bring lasting benefit and cures to cancer patients through innovative scientific discoveries and medicines.  \n\nWe will transform cancer care by taking a science-driven approach to drug discovery and development to achieve enduring clinical benefit.\nGuided by a deep understanding of the unique molecular features associated with each patient’s disease\, we will identify and understand pathways that drive cancer and establish the therapeutic potential of individual targets.\nBy combining laboratory and clinical investigation\, we will design strategies and medicines that target tumor cells\, drug resistance\, and the tumor microenvironment to achieve dramatic\, lasting\, benefit for cancer patients.\n\nPosition 1  \nThis intern will work with a postdoctoral fellow to investigate the impact of a kinase on the interaction between CD8 T cells and Antigen Presenting Cells (APC). He or she will use FACS analysis and various imaging techniques to investigate the above question.  \nPosition 2  \n\nGenerate and test mammalian cells edited by CRISPR technology.\nPerform various assays including western blotting\, qPCR\, ELISA\, FACS to determine changes in gene expression.\nOptimize culture conditions for primary cells and conduct in vitro phagocytosis assay.\n\nPosition 3 \nMetastases are the principal cause of death in patients with colorectal cancer (CRC). In order to develop effective methods for prevention and targeting of metastatic disease\, it is of crucial importance to better understand the cellular and molecular mechanisms regulating the metastatic cascade. The project will consist in evaluating the role of specific regulatory regions and signaling pathways in mediating the metastatic ability of colon cancer cells. First\, the intern will have to design\, clone and validate CRISPR-based tools (CRISPR KO or CRISPR i) to specifically and efficiently target genes and regulatory regions found in our in vivo screening and thought to be playing a key role in colon cancer cells metastatic ability. Also\, the intern will be involved in setting up a drug screening in order to assess the effect of different compounds on colon cancer cells in vitro. \nWho You Are  \nPosition 1  \n\nPreferred degree level: PhD\nPreferred majors are: Immunology\, Cell Biology.\nLab skills needed: FACS\, Immunofluorescence staining\, Cell Culture\, Fluorescence Microscopy\n\nPosition 2  \n\nPreferred degree level: BS\, MS\, or PhD\nMajors: Molecular Biology\, Cell Biology\, Immunology\nLab skills: mammalian cell culture\, cell transfection\, DNA/RNA preparation\, PCR\, FACS\n\nPosition 3  \n\nPreferred degree level: MS or PhD\nBackground in Molecular Biology\, Cell Biology\, Genetics\, Biochemistry\nPrevious experience with cell culture and molecular biology techniques (cloning\, digestion\, DNA preparation…) is highly desired\nPrevious experience with flow cytometry analysis and/or imaging techniques (confocal microscopy…) is preferred\nApplicants with good understanding of concepts in cancer biology/genomics/epigenetics will be prioritized
URL:https://ces.b2sg.org/event/genentech-19jan18/
LOCATION:Genentech\, 1 DNA Way\, South San Francisco\, CA\, 94080\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/05/genentech-logo.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180121
DTEND;VALUE=DATE:20180126
DTSTAMP:20171001T201442Z
CREATED:20170508T194630Z
LAST-MODIFIED:20171001T201442Z
UID:17903-1516492800-1516924799@ces.b2sg.org
SUMMARY:DNA and RNA Methylation (A7) in Vancouver\, Canada
DESCRIPTION:The meeting will begin on Sunday\, January 21 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Thursday\, January 25 with a closing plenary session from 17:00 to 19:00\, followed by a social hour and entertainment. We recommend return travel on Friday\, January 26 in order to fully experience the meeting. \nSpeakers: \nJuan Alfonzo\, Ohio State University\, USA  \nHoward Y. Chang\, Stanford University\, USA  \nJoseph F. Costello\, University of California\, San Francisco\, USA  \n Dana C. Dolinoy\, University of Michigan School of Public Health\, USA  \nJoseph R. Ecker\, The Salk Institute for Biological Studies\, USA  \n Michaela Frye\, University of Cambridge\, UK  \nFrançois Fuks\, Université Libre De Bruxelles\, Belgium   \nMargaret A. Goodell\, Baylor College of Medicine\, USA  \nChuan He\, University of Chicago\, USA  \nStacy M. Horner\, Duke University Medical Center\, USA  \nSuyun Huang\, MD Anderson Cancer Center\, USA  \nSteven E. Jacobsen\, University of California\, Los Angeles\, USA  \nSamie Jaffrey\, Weill Medical College of Cornell University\, USA  \nPeter A. Jones\, Van Andel Research Institute\, USA \nAlexander Meissner\, Harvard University\, Broad Institute\, USA  \nYunsun Nam\, University of Texas Southwestern Medical Center\, USA  \nTao Pan\, University of Chicago\, USA  \nTariq M. Rana\, University of California\, San Diego\, USA  \nAnjana Rao\, La Jolla Institute for Allergy and Immunology\, USA  \nGideon Rechavi\, Tel Aviv University\, Israel  \nWolf Reik\, Babraham Institute\, UK \nDirk Schübeler\, Friedrich Miescher Institute for Biomedical Research\, Switzerland  \nYang Shi\, Children’s Hospital Boston\, Harvard Medical School\, USA  \nYanhong Shi\, Beckman Research Institute of City of Hope\, USA  \nChunxiao Song\, University of Oxford\, UK  \nSohail F. Tavazoie\, Rockefeller University\, USA  \nTing Wang\, Washington University\, USA  \nAndrew Xiao\, Yale University\, USA  \n  \nDeadlines: \nScholarship Deadline: Sep 27\, 2017\n Discounted Abstract Deadline: Sep 27\, 2017 \n Abstract Deadline: Oct 27\, 2017\n Discounted Registration Deadline: Nov 28\, 2017 
URL:https://ces.b2sg.org/event/keystone-jan2018/
LOCATION:Fairmont Hotel Vancouver\, 900 W Georgia St\, Vancouver\, V6C 2W6\, Canada
CATEGORIES:Meetings
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180130
DTEND;VALUE=DATE:20180304
DTSTAMP:20180224T122119Z
CREATED:20180130T202854Z
LAST-MODIFIED:20180224T122119Z
UID:19628-1517270400-1520121599@ces.b2sg.org
SUMMARY:Postdoctoral Fellow
DESCRIPTION:The Faber laboratory has an opening for a postdoctoral fellow to study the rational combinations of epigenetic drugs for solid tumor therapies. The successful candidate will have a Ph.D. and a strong background in cancer biology. \nJob Type: Full-time \nRequired experience: \n\ncancer biology: 4 years
URL:https://ces.b2sg.org/event/vcu-30jan18/
LOCATION:Virginia Commonwealth University\, 907 Floyd Ave\, Richmond\, VA\, 23284\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/09/VCU-virginia-commonwealth-e1506279590219.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180208
DTEND;VALUE=DATE:20180309
DTSTAMP:20180208T212549Z
CREATED:20180208T212549Z
LAST-MODIFIED:20180208T212549Z
UID:19640-1518048000-1520553599@ces.b2sg.org
SUMMARY:Assistant Scientist
DESCRIPTION:The Department of Psychiatry is seeking an Assistant Scientist.  The Assistant Scientist will independently perform research involving neuroscience\, cancer\, epigenetics\, and molecular biology directed by the goals of the Principle Investigator Dr. Wahlestedt\, will collect\, analyze\, and summarize data\, prepare manuscripts and grant applications\, and supervise and train students and postdoctoral fellows in the laboratory.  \n \nThe minimum requirements are: Ph.D. in Cancer biology or Neuroscience. One (1) year of post doctoral experience required.  Five (5) years of relevant post-doctoral research experience – highly preferred. Experience as a teaching assistant – highly preferred. 
URL:https://ces.b2sg.org/event/umiami-8feb18/
LOCATION:University of Miami\, 1320 S Dixie Hwy\, Coral Gables\, FL\, 33146\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/07/u-miami-health.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180208
DTEND;VALUE=DATE:20180309
DTSTAMP:20180208T214059Z
CREATED:20180208T214034Z
LAST-MODIFIED:20180208T214059Z
UID:19642-1518048000-1520553599@ces.b2sg.org
SUMMARY:Postdoctoral Fellow
DESCRIPTION:Purpose Perform research in the lab and program of Dr. Song (Stephen) Yi\, Principal Investigator and Assistant Professor of Oncology at the LIVESTRONG Cancer Institutes.  \nEssential Functions Use systems and computational biology\, bioinformatics\, and proteomics approaches to identify genetic and epigenetic biomarkers\, and synthetic lethal mechanisms underlying cancer and immunity for personalized medicine. Perform bioinformatics data analyses and integrative mechanistic studies in a collaborative environment. Perform projects utilizing functional data from cell lines\, Patient Derived Xenograft (PDX) models and cancer patients. Perform data analysis include genomics\, proteomics\, network biology\, epigenetics and next-generation sequencing. Publish manuscripts\, write and edit grants\, progress reports. Participate in the design of a project. Lead a research effort in the direction set forth by the PI and the specific project.  \nMarginal/Incidental functions Other related functions as assigned.  \nRequired qualifications Ph.D. degree in bioinformatics\, systems and computational biology\, cancer biology\, immunology\, or relevant field within the last three years. The Dell Medical School is especially interested in qualified candidates who can contribute to diversity and excellence within the learning health system. At the Dell Medical School we strive to create a vital\, inclusive health ecosystem. To ensure alignment\, we follow these fundamental values: https://dellmed.utexas.edu/culture.  \nPreferred Qualifications Experience with cancer genomics\, CRISPR screens and next-generation sequencing analysis. 
URL:https://ces.b2sg.org/event/ut-8feb18/
LOCATION:University of Texas at Austin in Austin\, Austin\, TX\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180208
DTEND;VALUE=DATE:20180309
DTSTAMP:20180208T215043Z
CREATED:20180208T215029Z
LAST-MODIFIED:20180208T215043Z
UID:19648-1518048000-1520553599@ces.b2sg.org
SUMMARY:Postdoctoral Associate
DESCRIPTION:The Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine has an exciting opportunity for a Postdoctoral Associate for Ovarian Cancer Research. This position will have major responsibilities in all aspects of study conception\, design\, execution\, and analysis within a cancer epigenetics and genomics research laboratory.  \n \nThe minimum qualifications for this position are as follows: Ph.D.\, M.D./Ph.D.\, or M.D. in Genetics\, Biochemistry\, Molecular/Cell Biology\, Cancer Genetics\, Oncology\, or a closely related field of study. Computer skills with experience using Microsoft PowerPoint\, Excel\, Photoshop or Illustrator or other graphics software preferred. Excellent verbal and written communication skills with a strong command of the English language. 
URL:https://ces.b2sg.org/event/umiami2-8feb18/
LOCATION:University of Miami\, 1320 S Dixie Hwy\, Coral Gables\, FL\, 33146\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180208
DTEND;VALUE=DATE:20180310
DTSTAMP:20180209T023038Z
CREATED:20180209T023038Z
LAST-MODIFIED:20180209T023038Z
UID:19650-1518048000-1520639999@ces.b2sg.org
SUMMARY:Research Assistant
DESCRIPTION:GW’s Department of Microbiology\, Immunology\, and Tropical Medicine is searching for a full-time Research Assistant for Dr.Chiappinelli’s laboratory at the George Washington Cancer Center (https://smhs.gwu.edu/cancercenter/) and the Department of Microbiology\, Immunology\, & Tropical Medicine. Dr. Chiappinelli’s laboratory focuses on the epigenetic control of gene expression in cancer\, specifically of immune signaling in and from tumor cells. Our goal is to use epigenetic therapies to harness the power of the immune system to fight cancer.  \nThe Research Assistant will be responsible for performing experiments under the direction of the principal investigator in a biomedical research laboratory and contributing to general maintenance of the laboratory\, equipment and supplies. The individual will conduct experiments under the direct supervision of a postdoctoral fellow and will also receive mentoring and direct guidance from Dr. Chiappinelli in order to advance his/her career in academic research.  \nResponsibilities include: \n\nProvide assistance to research scientist\, postdoctoral scientists and lab manager\nOptimize\, develop\, qualify and execute the following assays: basic tissue culture\, PCR \, quantitative RT- PCR \, western blots\, and flow cytometry.\nGeneral maintenance of the laboratory. Maintain Good Laboratory Practice\, comply with biosafety guidelines\, keep inspection records and generate SOPs and reports.\nMaintain and troubleshoot equipment\nWork closely with graduate students\nParticipate in group meetings and present data\nOther duties as assigned. The omission of specific duties does not preclude the supervisor from assigning duties that are logically related to the position.\n\nIncumbent is expected to work well as part of a team and have enthusiasm for the practice of science.  \nMinimum Qualifications:\nQualified candidates will hold a BA/BS in a related discipline. Degree must be conferred by the start date of the position.  \nAdditional Required Licenses/Certifications/Posting Specific Minimum Qualifications:  \nPreferred Qualifications:\nEducation: Bachelor’s degree in biology\, chemistry\, or related field.  \nExperience: Previous laboratory experience (during undergraduate education or post-undergraduate).  \nPreferred qualifications include: experience handling laboratory animals\, experience in immunology-based and molecular biology techniques including flow cytometry\, quantitative RT- PCR \, nucleic acid extractions\, cell culture\, and aseptic technique. 
URL:https://ces.b2sg.org/event/gwu-8feb18/
LOCATION:George Washington University\, 2121 I St NW\, Washington\, DC\, 20052\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180208
DTEND;VALUE=DATE:20180310
DTSTAMP:20180209T024911Z
CREATED:20180209T024543Z
LAST-MODIFIED:20180209T024911Z
UID:19655-1518048000-1520639999@ces.b2sg.org
SUMMARY:Postdoctoral Fellow
DESCRIPTION:The Simone Laboratory in the Radiation Oncology Department at Thomas Jefferson University Hospital in Philadelphia\, PA is seeking an outstanding post-doctoral fellow to work in the area of cancer and radiation biology. Our laboratory focuses on using metabolic manipulation such as dietary alterations\, to improve standard cancer therapy such as radiation and chemotherapy. Mechanistically\, our focus is on microRNA alterations and downstream effectors. Our laboratory has a focus on hormonally responsive cancers such as breast and prostate cancer using both in vitro and in vivo models. From the pre-clinical data generated in the Simone Laboratory\, we have now opened multiple clinical trials with hormone-driven cancer patients which allows for the laboratory to evaluate translational endpoints of our basic science research. \nExperience Required : The candidate must be highly motivated\, independent and interested in our projects. The candidate must have PhD in molecular biology\, cell biology or a cancer related field. Although not absolutely necessary\, the ideal candidate will preferably have some experience with caloric restriction\, epigenetics\, microRNA or radiation biology. Expertise in microarray analysis\, RT-PCR\, ChIP\, cloning\, mouse husbandry\, in vivo tumor experiments are also a plus. The successful candidate will of course have mentoring so that career goals can be achieved\, but must be able to independently generate hypotheses\, design experiments to test the hypothesis\, performs routine and more difficult procedures\, analyze data and coherently present results in the form of presentations\, abstracts\, manuscripts and the basis for grant writing\, preparation and submission. In addition\, qualified candidates should have strong verbal and written communication skills\, and a demonstrated record of scientific achievement through peer-reviewed publications. Successful\, well-motivated candidates will join a highly interactive\, interdisciplinary team of researchers with diverse backgrounds and expertise in a collaborative scientific environment. Preference will be given to individuals with these skill sets who are now completing their thesis work and have at least one high-impact publication.
URL:https://ces.b2sg.org/event/tju-8feb18/
LOCATION:Thomas Jefferson University Hospital\, Philadelphia\, PA\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180208
DTEND;VALUE=DATE:20180310
DTSTAMP:20180209T035042Z
CREATED:20180209T031115Z
LAST-MODIFIED:20180209T035042Z
UID:19661-1518048000-1520639999@ces.b2sg.org
SUMMARY:Research Fellow
DESCRIPTION:Postdoctoral position is available in Prof. Jolanta Grembecka laboratory\, University of Michigan\, Ann Arbor\, to carry out an interdisciplinary project to study the effect of small molecules in in vitro and in vivo models of cancers and to pursue target validation studies using genetic approaches. We are seeking for a highly motivated postdoctoral fellow with extensive experience in cancer cell biology. The research will be focused on evaluation of the activity and the mechanism of action of novel small molecules blocking epigenetic proteins in cancer. This position requires the expertise in cell biology and molecular biology techniques\, including PCR\, qRT-PCR\, Western Blotting\, co-Immunoprecipitation\, ChIP\, ChIPSeq\, flow cytometry\, fluorescence microscopy\, immunostaining. Prior work experience with animals such as transgenic mice and xenograft models of cancer would be desired. Successful candidate will be a part of an interdisciplinary team focused on development and pre-clinical evaluation of novel anti-cancer drug candidates. Required Qualifications* \nApplicant must have PhD in biology or related field. The candidates must be a first author on at least 2-3 publications. This position requires extensive experience in cell and molecular biology techniques. Furthermore\, excellent oral and written communication skills in English are required as well as the ability to conduct independent scientific investigations.
URL:https://ces.b2sg.org/event/umich-8feb18/
LOCATION:University of Michigan\, 500 S State St\, Ann Arbor\, MI\, 48109\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2017/05/uni-michigan.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180208
DTEND;VALUE=DATE:20180301
DTSTAMP:20180209T040857Z
CREATED:20180209T040240Z
LAST-MODIFIED:20180209T040857Z
UID:19664-1518048000-1519862399@ces.b2sg.org
SUMMARY:Research Specialist
DESCRIPTION:The University of Illinois College of Medicine has a Research Specialist position open for studying the pathogenesis of medulloblastoma (MB) and developing new molecular subgroup specific therapeutic approaches in MB. These projects investigate the roles of immune checkpoints and epigenetic modifiers in the development of MB and establish the logical basis for novel therapy using transgenic/knockout mouse models of MB. The candidate will also be involved in other projects in the laboratory\, focusing on basic science and Cancer Biology. The successful candidates will have a Bachelor’s degree in science or related field. Master’s degree or PhD in science is preferred. Also a minimum of 3 years intensive experience in two or more of the following areas: cancer biology\, epigenetics\, molecular biology\, immunology\, mouse model systems\, and viral vectors. For fullest consideration\, please respond by October 31\, 2017. Applicants should submit a cover letter\, curriculum vitae\, and the names and contact information of three references. To apply\, click on the following link: https://jobs.uic.edu/job-board/job-details?jobID=86285 . The University of Illinois is an affirmative action/equal opportunity employer. Minorities\, women\, veterans\, and individuals with disabilities are encouraged to apply. The University of Illinois may conduct background checks on all job candidates upon acceptance of a contingent offer. Background checks will be performed in compliance with the Fair Credit Reporting Act.  \nDuties:  \nJob Duties \n• Manage and lead research projects for publications in peer-reviewed journals and presentations at scientific meetings. \n• Formulate experimental methods and conduct research experiments and analyses. \n• Prepare and write scientific findings and works for publications in peer-reviewed journals and grant applications\, and present findings and works at scientific meetings. \n• Participate in designing experiments\, teaching students and lab personnel\, and lab meeting to enhance and promote research and educational activities. \n• Ensure compliance with regulations and good laboratory practice and maintain research records. \n• Assist the principal investigator\, collaborators and lab personnel with research and educational activities.  \nQualifications: \nQualifications  \nBachelor’s degree in science or related field. Master’s degree or PhD in science preferred.  \n• Minimum 3 years intensive related research experience cancer biology\, immunology\, molecular and cellular biology or related biomedical fields.  \n• Strong experience and publications in two or more of the following areas: cancer biology and cellular\, epigenetics\, immunology\, in vivo mouse models\, exosomes\, microRNAs and adeno-associated vectors.
URL:https://ces.b2sg.org/event/uic-8feb18/
LOCATION:University of Illinois at Chicago\, Chicago\, IL\, United States
CATEGORIES:Jobs
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180209
DTEND;VALUE=DATE:20180310
DTSTAMP:20180209T063129Z
CREATED:20180209T062613Z
LAST-MODIFIED:20180209T063129Z
UID:19669-1518134400-1520639999@ces.b2sg.org
SUMMARY:Postdoctoral Fellow
DESCRIPTION:  \nAccording to the National Institute of Health (NIH) and the National Science Foundation (NSF)\, a postdoc is an individual who has received a doctoral degree (or equivalent) and is engaged in a temporary and defined period of mentored advanced research training to enhance the professional skills and research independence needed to pursue his or her chosen career path. In addition\, according to the National Postdoc Association (NPA)\, Postdoctoral appointees can pursue basic\, clinical or translational projects so long as their primary effort is devoted toward their own scholarship. Postdocs are essential to the scholarly mission of the mentor and host institution\, and thus are expected to have the freedom to publish the results of their scholarship. \nCharacteristics of a postdoctoral appointment:  \nIt is expected that postdocs at MCW\, with the assistance of their supervisor\, will: \n\nTransition to career independence through the development of professional skills that enable the postdoc to actively pursue a career of his/her own choosing.\nBe supervised by at least one senior scholar who actively promotes the postdoc’s professional development.\nEstablish an individual development plan (IDP) that incorporates equally the postdoc’s career and training goals and the mentor’s research goals.\nPursue basic\, clinical\, or translational projects so long as effort is focused primarily on research.\nPublish results of the postdoc’s research and scholarship during their appointment.\nThe postdoctoral appointment is temporary by nature\, the aggregate amount of time spent as a postdoc is recommended to not exceed five years (not including family medical leave or maternity/paternity leave).\nAs postdocs are important members of the host institution’s community\, appropriate levels of compensation\, health care\, and other benefits commensurate with their essential status should be afforded\, independent of the postdoc’s source of funding.\n\n\nPrimary Functions \n \n\nPlan\, design and execute complex research studies\, procedures and protocols.\nParticipate in discovery projects.\nCoordinate research study activities; lead and manage projects.\nOversee organization\, synthesis and analysis of data and findings.\nPrepare scientific reports\, outcome findings and scientific manuscripts.\nParticipate in meetings with principle investigator and research staff in which you will evaluate/interpret the validity of data\, develop methodologies\, and design and evaluate lab procedures.\nMaintain supplies\, may require negotiation with vendors\, and track purchase orders.\nMay oversee the work of laboratory personnel including training and development as well as daily work direction\, delegation and establishing priorities.\n\n\nKnowledge – Skills – Abilities  \nRequired knowledge: biology\, chemistry\, mathematics\, statistics\, documentation\, records management\, data utilization\, complex problem solving\, critical thinking\, resource management\, and writing skills \nSkills and abilities: Necessary research skills include standard molecular and cellular biology techniques. Qualified candidates should have outstanding critical thinking and problem-solving skills\, excellent written and oral skills\, as well as the ability to collaborate with others in a team-oriented environment. Experience in epigenetics and/or mouse models\, especially cancer-related\, would be an asset.
URL:https://ces.b2sg.org/event/mcw-8feb18/
LOCATION:Medical College of Wisconsin\, Milwaukee\, WI\, United States
CATEGORIES:Jobs
ATTACH;FMTTYPE=image/jpeg:https://ces.b2sg.org/wp-content/uploads/2018/02/MCW-medical-college-wisconsin-1.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180210
DTEND;VALUE=DATE:20180215
DTSTAMP:20171001T200958Z
CREATED:20170507T162805Z
LAST-MODIFIED:20171001T200958Z
UID:17852-1518220800-1518652799@ces.b2sg.org
SUMMARY:Cancer Epigenetics: New Mechanisms\, New Therapies (B4) in Breckenridge\, CO\, USA
DESCRIPTION:Bringing together both the scientific and the pharmaceutical communities\, this Keystone Symposia meeting will will focus on:  \n1) The newest findings on the mechanisms by which epigenetic pathways are established and maintained in normal and stem cells\, and how these go awry during aging and cancer\, with a special emphasis on histone modifications\, chromatin remodeling and the unexpected increased number of DNA modifications ((hydroxy)methylcytosine and methyladenine);  \n2) The growing roles of noncoding RNAs in cancer and the emergence of the new and exciting realm of RNA epigenetics;  \n3) Use of new omics technologies to interrogate altered epigenetic landscapes in tumors and assess their clinical implications;  \n4) Novel and promising therapeutic drugs aimed at reversing specific epigenetic alterations. Ultimately\, the meeting will provide great opportunities for senior and junior scientists to meet the leaders in the field from both academia and industry\, hence forging exciting interdisciplinary interactions and creating potential new collaborations in the booming area of cancer epigenetics. \nInvited Speakers:  \nKaren Adelman\, Harvard Medical School\, USA \nGeneviève Almouzni\, Centre National de la Recherche Scientifique\, France \nStephen B. Baylin\, Johns Hopkins University School of Medicine\, USA \nAznar Benitah\, ICREA and Institute for Research in Biomedicine\, Spain \nShelley L. Berger\, University of Pennsylvania\, USA \nJames E. Bradner\, Novartis Institutes for BioMedical Research\, USA \nAnne Brunet\, Stanford University\, USA \nHoward Y. Chang\, Stanford University\, USA \nMark A. Dawson\, Peter MacCallum Cancer Centre\, Australia \nLuciano Di Croce\, Centre for Genomic Regulation\, Spain \nMichaela Frye\, University of Cambridge\, UK \nFrançois Fuks\, Université Libre De Bruxelles\, Belgium \nChuan He\, University of Chicago\, USA \nPeter A. Jones\, Van Andel Research Institute\, USA \nCigall Kadoch\, Dana-Farber Cancer Institute\, Harvard Medical School\, USA \nTony Kauzarides\, University of Cambridge\, UK \nElectron Kebebew\, National Cancer Institute\, USA \nRobert E. Kingston\, Massachusetts General Hospital\, USA \nRobert MacLeod\, Ionis Pharmaceuticals\, Inc.\, USA \nChris Marine\, VIB\, Belgium \nRobert A. Martienssen\, Cold Spring Harbor Laboratory\, USA \nRonan C. O’Hagan\, Merck Research Laboratories\, USA \nKornelia Polyak\, Dana-Farber Cancer Institute\, Harvard Medical School\, USA \nRab K. Prinjha\, GlaxoSmithKline\, UK \nGideon Rechavi\, Tel Aviv University\, Israel \nDanny F. Reinberg\, HHMI/New York University\, USA \nAli Shilatifard\, Northwestern University\, USA \n  \nDeadlines: \nScholarship Deadline: Oct 10\, 2017 \n Discounted Abstract Deadline: Oct 10\, 2017 \n Abstract Deadline: Nov 8\, 2017 \n Discounted Registration Deadline: Dec 12\, 2017  \nScientific Organizers: François Fuks and Anne Brunet\n 
URL:https://ces.b2sg.org/event/keystone-feb2018/
LOCATION:Beaver Run Resort\, 620 Village Rd\, Breckenridge\, CO\, 80424\, United States
CATEGORIES:Meetings
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END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20180224
DTEND;VALUE=DATE:20180325
DTSTAMP:20180224T123413Z
CREATED:20180224T123337Z
LAST-MODIFIED:20180224T123413Z
UID:19678-1519430400-1521935999@ces.b2sg.org
SUMMARY:Postdoctoral Research Associate
DESCRIPTION:Preferred Education: \nPh.D. Biology\, Biochemistry\, Medicine\, or related field. \nPreferred Experience: \nExperience in physiology\, anatomy\, and surgery using preclinical models of colon cancer. Performed necropsies\, clinical and/or laboratory experience. Proficient in molecular biology techniques\, such as immunoblotting\, PCR\, RT-PCR\, or cell culture and cloning. Experience in performing rodent tumor bioassays following approved protocols using intra-oral and intra-peritoneal injections. \nRequired Special Knowledge\, Skills\, and Abilities: \nAbility to multi-task and work cooperatively with others. Ability to perform all tasks and job responsibilities safely without injury to self and others\, in compliance with A&M System and TAMHSC guidelines. Provide a safe environment that fosters respect\, inclusion\, and equality. \nJob Responsibilities \n\nPerform Procedures: Perform endoscopies and polypectomies on live study animals\, helping to develop/improve surgical resection protocols on rodent small intestine and colon.\nExperiments: Conduct cell culture\, molecular\, biochemical\, and animal studies to determine the action of chemopreventive compounds in cell culture and tumorigenicity assays. Perform cell culture experiments and molecular techniques such as PCR\, RT-PCR\, Western blotting\, RNA-seq\, and DNA methylation assays to investigate epigenetic mechanisms in GI lesions.\nResearch: Participate in joint projects involving faculty\, postdoctoral fellows\, and research assistants. Assist with research grant proposals and provide publishable reports for conference and journal presentation. This will include library research into new approaches\, the preparation of tables\, graphs\, photographs\, and figures\, and assist in manuscripts and grant proposals. Participate in weekly lab meetings within the center and in local/regional programs relevant to ongoing projects. Participate in joint projects involving faculty\, junior lab personnel\, and graduate students. Provides assistance to graduate students and junior lab personnel.
URL:https://ces.b2sg.org/event/tam-24feb18/
LOCATION:Texas A&M University Health Science Center\, 8441 Riverside Pkwy\, Bryan\, TX\, 77807\, United States
CATEGORIES:Jobs
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DTSTART;VALUE=DATE:20180224
DTEND;VALUE=DATE:20180326
DTSTAMP:20180225T010655Z
CREATED:20180225T010655Z
LAST-MODIFIED:20180225T010655Z
UID:19684-1519430400-1522022399@ces.b2sg.org
SUMMARY:Research Assistant Professor
DESCRIPTION:An individual is sought to independently direct a project investigating molecular cross-talk between epigenetics and chromatin organization in normal and malignant hematopoiesis using molecular biology\, biochemistry\, fluorescence microscopy\, and NGS-based epigenome profiling methods. The goal of these studies is to identify novel targets and design therapeutic interventions to prevent or delay the development of\, and to treat acute myeloid leukemia.  \n\nDesign and coordinate projects to carry out experiments in animal models of myeloid malignancies and pre-leukemic conditions to evaluate potential therapeutic agents\nPerform epigenomic and chromatin profiling experiments such as ChIP-seq\, ATAC-seq\, MAPit-PATCH\, WGBS\nUse wide field fluorescence and and confocal microscopy to document dynamic changes in chromatin structure in live and fixed hematopoietic cells\nAnalyze\, interpret\, and visually organize data\nWrite manuscripts\nAssist with grant proposal preparation\nWrite technical reports\nTrain and supervise technical personnel\, assist with mentoring of graduate students\nPresent research results at meetings\n\n\nAdvertised Salary: \nCommensurate with education and experience  \nMinimum Requirements: \nPh.D. in molecular biology\, biochemistry\, cancer biology\, molecular genetics\, or related field  \nPreferred Qualifications: \n5+ years of research experience  \nExpertise in cancer epigenetics\, chromatin biology\, transcriptomics\, functional genomics\, and other NGS-based methods as demonstrated by published papers in peer reviewed scientific journals  \nSpecial Instructions to Applicants: \nInterested candidates must apply online. Please upload most recent CV\, Cover Letter of interest\, and three references with contact information. 
URL:https://ces.b2sg.org/event/unifl-24feb18/
LOCATION:University of Florida\, Gainesville\, FL\, 32611\, United States
CATEGORIES:Jobs
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DTSTART;VALUE=DATE:20180224
DTEND;VALUE=DATE:20180326
DTSTAMP:20180225T013654Z
CREATED:20180225T013454Z
LAST-MODIFIED:20180225T013654Z
UID:19686-1519430400-1522022399@ces.b2sg.org
SUMMARY:Laboratory Coordinator
DESCRIPTION:We are seeking to recruit a Laboratory Coordinator in the laboratory of Dr. Kevin Gardner in the Department of Pathology and Cell Biology. The Gardner lab studies basic mechanisms of epigenetic gene regulation in breast cancer using both model systems and patient derived material (Proc Natl Acad Sci U S A. 2009 Nov 17;106(46): 19286-91; Nat Struct Mol Biol. 2010 Dec;17(12): 1406-13; Nat Commun. 2012 Jan 17;3:633; Nat Commun. 2013;4:1449).  \nResponsibilities include but are not limited to: \n\nManaging the day to day operations of the laboratory\nMaintenance of cell lines\nCarrying out immunoprecipitation assays\nOrdering and maintaining inventory of laboratory supplies.\nKeeping track of orders and confirming billing\nSetting up and performing experiments involving tissue culture\, western blot\, DNA\, RNA\, analysis\nMaintaining records pertaining to the laboratory\, including records of experimental results.\nOperating\, maintaining and troubleshooting complex equipment (e.g. ABI 7300 Real-Time PCR system)\nAssisting in the training of new hires\, Support Staff employees\, Students and Fellows in laboratory procedures\nImplementing safety regulations\nPerforming other related duties as necessary to the functioning of the laboratory.\n\nMinimum Qualifications for Grade \nApplicant MUST meet these minimum qualifications to be considered an applicant  \nRequires a bachelor’s degree plus two years of related experience or equivalent in education\, training and experience.  \nAdditional Position-Specific Minimum Qualifications \nApplicant MUST meet these minimum qualifications to be considered an applicant  \nThe successful candidate must have extensive common knowledge and skill with basic molecular and cell biology\, including mammalian tissue culture\, RNA isolation\, QPCR\, PCR\, recombinant DNA technology\, immunoblotting\, immunohistochemistry\, viral and plasmid vectors construction\, in situ hybridization\, fluorescence microscopy\, ELISA assay\, conventional reporter fluorescent and bioluminescent assays\, in situ hybridization and fluorescence microscopy.  \nMust be computer literate (MS Access\, MS Excel\, Windows and/or Mac).  \nAbility to work independently\, under minimal supervision.  \nMust demonstrate excellent interpersonal and communication skills.  \nThe incumbent should be able to work independently\, be very well organized and reliable and enjoy working in an interdisciplinary and highly collaborative atmosphere where technical support will be provided for all projects in the lab.  \nSpecial Instructions  \nPreferred Qualifications  \n\nFive years of related experience.\nBachelor’s degree in chemistry\, biology or related science
URL:https://ces.b2sg.org/event/cu-24feb18/
LOCATION:Columbia University Medical Center\, 630 W 168th St\, New York\, NY\, 10032\, United States
CATEGORIES:Jobs
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DTSTART;VALUE=DATE:20180224
DTEND;VALUE=DATE:20180326
DTSTAMP:20180225T023919Z
CREATED:20180225T023901Z
LAST-MODIFIED:20180225T023919Z
UID:19689-1519430400-1522022399@ces.b2sg.org
SUMMARY:Post-Doctoral Fellow
DESCRIPTION:The Espinosa Laboratory in the Cancer Division of the Department of Pharmacology at the University of Colorado Denver | Anschutz Medical Campus is seeking independent and creative postdoctoral fellows. The Espinosa Lab utilizes an integrated system of functional genomics and mechanistic studies aimed at making biological discoveries with clear translational potential. Most of our current studies are focused on harnessing the power of pleiotropic transcription factors for cancer treatment Examples of ongoing projects are: \n\nElucidation of gene networks governed by transcription factors involved in cancer. We employ functional genomics tools to elucidate the signaling cascades driven by cancer-relevant transcription factors such as p53 and HIF1A across different cell types and stimuli. We aim to elucidate molecular mechanisms that control the cellular response upon activation of these transcription factors\, from enhancer priming to metabolic control\, with the ultimate goal of harnessing these mechanisms for therapeutic purposes (e.g. Galbraith et al.\, Cell 2013\, Allen et al.\, eLife 2014\, Andrysik et. al.\, Genome Res 2017).\nMechanistic studies of transcriptional coactivators and chromatin regulators with oncogenic and tumor suppressive functions. Using a multidimensional approach\, from biochemistry to functional genomics\, we investigate the role of specific transcriptional coactivators and chromatin factors in cancer development. We are particularly interested in the role of the Mediator Complex in oncogenesis and tumor suppression (e.g. Donner et al.\, Mol Cell 2007\, Donner et al.\, Nature Struct Mol Biol. 2010\, Galbraith et al.\, Cell 2013\, Perez-Perri et al. Cell Reports 2016).\nPharmacological manipulation of transcription factors and cofactors for therapeutic purposes. Our goal is to identify effective strategies to employ novel biologically targeted therapeutics modulating the activity of transcription factors\, cofactors and chromatin regulators for cancer treatment. Presently\, we are focused on several first-in-class drugs that modulate transcription factors\, Mediator-associated kinases\, and epigenetic readers (e.g. Sullivan et al.\, Nat Chem Biol. 2012\, Andrysik et al.\, Cell Reports 2013).\nRoles of Interferon signaling in Down syndrome and cancer. We are particularly interested in understanding how hyperactivation of Interferon signaling in people with Down syndrome may contribute to the clinical impacts of trisomy 21\, including the lower incidence of solid malignancies and higher incidence of leukemias observed in this population (e.g. Sullivan et al.\, eLIFE 2016; Sullivan et al.\, Scientific Reports 2017).\n\nOur hope is that these courses of study will lead to clinically actionable discoveries and ultimately improve patient outcomes as well as our understanding of human biology in general. All projects provide ample opportunity for gaining experience with genomic methods to study gene transcription\, expression\, and epigenetic regulation. We also frequently employ shRNA and CRISPR technology\, along with a host of additional advanced molecular\, biochemical\, and genomic techniques. \nQualifications \nMinimum Requirements: \n\nPh.D. in molecular biology or a related field\n\n\nExcellent written and verbal communication skills in English\n\n\nProven ability to work independently within a research lab\n\n\nExperience with mammalian tissue culture\n\nDesired or preferred: \nExperience with molecular biology methods\, such as: \n\nRT/quantitative PCR\nWestern blotting\nRNA interference\nCRISPR / genome editing\nLenti/retroviral production and transduction\nFlow cytometry\n3 years mammalian tissue culture experience\nExperience with rodent models\nExperience with generation and analysis of genomic sequence data\nExperience with standard bioinformatics tools\nExperience with statistical programming\, such as R
URL:https://ces.b2sg.org/event/unico-24feb18/
LOCATION:University of Colorado – School of Medicine\, Aurora\, CO\, United States
CATEGORIES:Jobs
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DTSTART;VALUE=DATE:20180224
DTEND;VALUE=DATE:20180326
DTSTAMP:20180225T031233Z
CREATED:20180225T025805Z
LAST-MODIFIED:20180225T031233Z
UID:19693-1519430400-1522022399@ces.b2sg.org
SUMMARY:Senior Research Associate
DESCRIPTION:Constellation Pharmaceuticals is a premier epigenetics company\, focused on the discovery and development of novel\, small molecules targeting chromatin regulatory proteins in tumor and immune cells for therapeutic applications in oncology. Our unique discovery platform integrates our understanding of chromatin-regulatory mechanisms with cancer and immune pathways to optimize our drug discovery activities and fully enable the clinical translation of our programs. Our translational capabilities are being currently expanded to ensure the differentiated clinical development of our clinical and pre-clinical assets and we look for talented and experienced individuals who want to participate in developing novel cancer therapeutics. \nResponsibilities: \n\nWork closely with scientists to design and execute cell-based phenotypic and mechanism of action assays in a variety of assay platforms\nGenerate\, analyze\, and catalog data with database tools such as Genedata and software tools such as GraphPad Prism\nPerform standard molecular biology and biochemistry techniques according to established protocols\nDocument all work in electronic notebooks and present data internally at group meetings\nRequirements: \n\nBS/MS in biology or other relevant field\nA minimum of 2-3 years of postgraduate laboratory experience (industry setting preferred)\nExperience with mammalian cell culture and standard molecular biology techniques is essential\nExperience with a variety of cell-based assays (Cell Titer Glo\, ELISA\, flow cytometry) is essential\nAbility to adapt to new roles in a dynamic working environment\, detail oriented with excellent time management skills\nStrong oral and written communication skills and an ability to successfully work as part of an integrated\, interdisciplinary team
URL:https://ces.b2sg.org/event/constellation-24feb18/
LOCATION:Constellation Pharmaceuticals\, 215 First Street\, Cambridge\, MA\, 02142\, United States
CATEGORIES:Jobs
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