The successful candidate will serve as an integral member of a multidisciplinary drug discovery project team developing novel inhibitors targeting epigenetic enzymes implicated in cancer. As a member of the Lead Discovery Team, the qualified candidate will be required to employ a variety of in vitro biochemical techniques to develop enzyme assays and explore the mechanism of action for small-molecule inhibitors.

Responsibilities

• Assess activity and substrate specificity for enzyme preparations
• Design and develop enzymatic assays for inhibitor identification
• Validate screening hits through mechanism of action studies on small-molecule inhibitors
• Maintain a panel of routine screening assays for specific project teams
• Maintain and track an inventory of biochemical reagents
• Manage good working relationships with CRO vendors providing high quality biochemical data
• Generate SOP documents
• Manage uploading of data to an internal database

Requirements

• MS in Biochemistry or a related field plus minimum 3-5 years of relevant industry experience, or PhD in Biochemistry or a related field

• Ability to plan and troubleshoot experiments
• Exceptional time management skills
• Unparalleled analytical, organizational and communication skills
• Ability to work well under pressure and drive projects that affect critical timelines