There is an immediate opening for a research technician in Qi group at the Dana-Farber Cancer Institute to look for exceptional researcher in Chemistry and Chemical Biology field. The Qi lab studies gene regulatory pathways using the emerging discipline of chemical biology. Successful candidates will work with an interdisciplinary team of scientists including medicinal chemists, biochemists, computational biologists, and cancer biologists to develop novel inhibitors of chromatin modifying enzymes, such as methyltransferases, demethylases as well as other epigenetic targets and transcription factors. The successful candidate will perform research that establish fundamental insights to cancer biology using novel small molecule inhibitors to gain mechanistic understanding in cancer therapy. We expect that novel therapeutics for human clinical investigation will emerge directly from these efforts through academic/industry collaborations.

This position will assist scientists in performing scientific research, development and/or clinical tasks of varying complexity. In general, this position will assist in the set up, operation and maintenance of laboratory instruments and equipment, monitoring experiments, making observations and calculating and recording results. 

We are looking for candidates who have at least a two-year availability.

• Skill in organic chemistry, compound characterization with NMR and mass spec
• Understanding the medicinal chemistry for small molecule inhibitor design
• Performing laboratory experiments and conducting data analysis
• Designing experiments and executing protocols
• developing and executing design and synthesis small molecule inhibitors while investigating novel biological mechanisms of action of inhibitors in cancer with team
• Maintaining accurate records, writing reports, and preparing presentations
• Contribute to the organization of the overall laboratory and safety
• Set up, adjust, calibrate, clean, maintain and troubleshoot equipment.
• Clean, maintain and prepare supplies and work areas and may be responsible for ordering of supplies. Collaborates with Purchasing and may be responsible for negotiating with vendors.
• Conduct standardized biological, microbiological or biochemical tests and laboratory analyses, including the collection of information and samples from organic substances, such as blood, drugs, and animals.
• Isolate, identify and prepare specimens for examination.
• Analyze experimental data and interpret results to write reports and summaries of findings, including grant preparation and presentations, and look for opportunities to co-author publications. May be expected to participate in formal and information presentations of results to staff. 
• Participate in grant application process and manuscript preparation as required.
• Maintains detailed notebook of all work-related activities.
• Monitors laboratory work to ensure compliance with Environmental Health and Safety information as well as the standard operation procedures specific to each laboratory.
• Expected to provide intellectual and interactive commitment to position by keeping up with appropriate literature and research publications.
• May be responsible for the development, modification and improvement of standard operating procedures.
• Uses computers, computer-interfaced equipment, robotics or high-technology applications to perform work duties.
• May be responsible for designing and executing advanced experiments and setting strategy. 
• May be responsible for the examination of animals and specimens to detect the presence of disease or other problems.
• May be responsible for monitoring laboratory budgets.

• Bachelor’s Degree required with a major in chemistry or biochemistry preferred. 
• Knowledge of information and techniques in the fields of organic chemistry, medicinal chemistry, or biochemistry
• Must have excellent communication skills (written and verbal) and be able to work with a wide variety of faculty and staff.
• Enthusiastic, team player, and self-motivated individual
• Ability to analyze information and use logic to address work-related issues and problems.
• Must have attention to detail and be thorough in completing work tasks.
• Ability to work within a team environment.