One (1) staff scientist position is available in October 2019 in the Laboratory of Genome Integrity (Center for Cancer Research, National Cancer Institute, National Institutes of Health) to use computational methods in the study of mechanisms involved in DNA double-strand break repair and the roles of repair and replication proteins in a variety of cancers that include leukemias and breast cancers, using mouse models. The ideal candidate will play a leading role in providing computational and biological insight by analyzing large data sets derived from genomics, epigenetics and proteomics experiments. The position will emphasize efforts to understand gene regulation, chromatin, regulatory and coding variation and its relation to cancer. The position will support all laboratory investigators who use applications involving high-throughput DNA sequencing methods for a variety of assays, including RNA-seq, exon sequencing, ATAC-seq, DNase-seq, ChIP-seq and newer and cutting-edge methodologies such as END-seq that have recently been developed.  Salary is commensurate with experience.