A Postdoctoral position in Hematopoietic Stem Cell Biology is available in the laboratory of Peter Kurre, M.D., at the Comprehensive Center for Bone Marrow Failure. The Laboratory has longstanding expertise in Hematopoietic stem cell biology, including the development of preclinical approaches to Hematopoietic Stem Cell Gene Therapy. Ongoing work is focused on the development and refinement of anchoring lentivector designs with reduced propensity for genomic integration and mutagenicity. In a rapidly growing area of science, investigations will involve a wide range of methods in virology, vectorology, cell-, molecular biology imaging and bioinformatics tools. The postdoctoral fellow will, under the direction/guidance of a mentor Dr. Mortimer Poncz, assume responsibility for a specific, on-going research project.

The successful candidate will be highly motivated and creative. Excellent verbal and written communication skills are critical. Scrupulous attention to detail, good record keeping, the ability to work independently, in an expanding dynamic workgroup are essential. Candidates must have a recent Ph.D., D.V.M, or M.D./Ph.D. in the biological sciences. Experience with mammalian cell culture (established cell lines and primary leukemia samples), molecular and cell biology techniques, flow-cytometry, and mouse models are desirable. The position is funded by NIH funds and private grants and by the The Children’s Hospital of Philadelphia, with an understanding that the applicant will compete for trainee funding as part of their own career development.

The successful candidate will thrive in a multi-disciplinary, collaborative team to extend, refine and enhance skills necessary for professional and career development, and broaden his/her scientific background by acquiring new research capabilities. It is expected that this individual will conduct independent scholarly research, and will contribute directly to the overall research goals of the project and the research group. Postdocs will participate in project planning, recording and interpretation/evaluation of data, and communication of results. The candidate will acquire critical technical and lab management skills for their own career, and to be proficient at manuscript/grant writing; postdocs will participate in seminars, lectures, poster sessions and presentations at national meetings. Postdoctoral fellows also will participate in the supervision of junior lab members, develop new methods and protocols for research, and assist with the development of other research projects in the lab.

Postdoctoral fellows at The Children’s Hospital of Philadelphia receive mentored training in a premier scientific and collaborative environment that includes the resources of the adjacent University of Pennsylvania.

To learn more about the CHOP Research Institute and the research programs visit: http://research.chop.edu.

Job Responsibilities

1. Conduct independent scholarly research and develop new methods and protocols
2. Participate in project planning, recording and evaluation of data
3. Acquire technical, lab management and grant writing skills
4. Participate in seminars, lectures, poster sessions and presentation at national meetings
5. Supervise junior lab members
6. Assist with other research projects

Required Education and Experience

• A terminal degree PhD, MD, DVM, etc.
• According to the CMS (Centers for Medicaid and Medicare Services) a copy of diploma or transcript is required as proof of academic achievement for all non-laboratory personnel performing non-waived POC testing