Post Doctoral Fellow positions are available in the laboratory of Dr. Matthew Weitzman, at the Children’s Hospital of Philadelphia (CHOP) and the University of Pennsylvania (Penn). Our lab is part of the rich scientific environment on the CHOP/Penn campus that includes multiple areas of virology, immunology, cancer, and epigenetics. We are located in the new Colket Translational Research Building as part of the Division of Cancer Pathobiology, in the Department of Pathology & Laboratory Medicine. The lab is also part of the Center for Childhood Cancer Research (CCCR), the Center for Cellular & Molecular Therapeutics (CCMT), the Penn Institute for Immunology (IFI), the Penn Epigenetics program, and Penn Center for AIDS Research (CFAR).

The lab’s research focuses on virus-host interactions and the use of viruses as model systems to study DNA repair, signaling, cell biology, replication, innate host defenses and gene delivery. We are interested in virus replication and the resulting cellular responses. We study the intersection of virus and host pathways during infection and how they reveal insights into fundamental cellular mechanisms. We are particularly interested in recognition and processing of viral genomes by DNA repair and APOBEC pathways. We are using virus systems to study signaling, ubiquitination and degradation, and transcriptional silencing. Viral model systems include adeno-associated virus (AAV), adenovirus (Ad) and herpes simplex virus (HSV).

Job Responsibilities

1. Conduct independent scholarly research and develop new methods and protocols
2. Participate in project planning, recording and evaluation of data
3. Acquire technical, lab management and grant writing skills
4. Participate in seminars, lectures, poster sessions and presentation at national meetings
5. Supervise junior lab members
6. Assist with other research projects

Required Education and Experience

• A terminal degree PhD, MD, DVM, etc.
• According to the CMS (Centers for Medicaid and Medicare Services) a copy of diploma or transcript is required as proof of academic achievement for all non-laboratory personnel performing non-waived POC testing

Preferred Education, Experience & Cert/Lic

The successful applicant will become part of a highly interactive and collaborative team. Applicants must have a Doctoral degree in a related discipline with good skills in molecular biology, biochemistry and cell biology, and a strong motivation to learn new techniques and research topics. A background in virology and/or DNA repair would be advantageous. It is expected that this individual will conduct independent scholarly research, and will contribute to the overall research goals of the project and the research group.

The Children’s Hospital of Philadelphia Research Institute is an interdisciplinary institution dedicated to conducting basic, clinical and translational research on conditions and diseases that affect children, and is part of The Children’s Hospital of Philadelphia (CHOP) and University of Pennsylvania research community.

All CHOP employees who work in a patient building or who provide patient care are required to receive an annual influenza vaccine unless they are granted a medical or religious exemption.