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Performs basic research duties under the supervision/direction of a Physician (Principal Investigator).

The Yun laboratory studies multiple aspects of cancer stem cell biology, employing techniques in genetics, genomics, molecular biology, cell biology, and biochemistry.  We are currently focusing on understanding mechanisms that promote cancer stem cell survival and self-renewal in medulloblastomas and glioblastomas (GBMs), using genetically defined mouse models, PDX models, and primary human cancer stem cell cultures.  Ongoing projects include: 1) elucidating molecular mechanisms of therapy resistance in brain cancer stem cells, 2) developing new small molecule and antibody based inhibitors to target cancer stem cells, 3) validation of a new experimental platform for drug testing, 4) interrogation of epigenetic changes in stem cells.

We are looking for a postdoctoral fellow with a strong background in cancer biology, stem cell biology, bioengineering, pharmacology, or epigenetics.

Houston Methodist Research Institute (HMRI) is a non-profit, academic research institute affiliated with the Weill Cornell Medical College and provides unique translational research opportunities. HMRI is located in the Texas Medical Center, adjacent to Rice University, Baylor College of Medicine, and MD Anderson Cancer Center, providing ample opportunities to interact with researchers in these neighboring institutions. We work hard and play hard and love what we do.  We are looking for colleagues with demonstrated passion for science, strong work ethics, and excellent interpersonal and organizational skills. Candidates with a Ph.D. or equivalent degree with previous experience in relevant area are encouraged to apply. Salary will be commensurate with established NIH guidelines.

**Applicants should include a CV, names of three references, and a cover letter describing research interest and background. 

Please send to:
Kyuson Yun, Ph.D.
Email: kyun@houstonmethodist.org

M.D. or Ph.D required

Experience requirements will vary depending on the field of research.
Postdoctoral Fellow 0 no Postdoc experience required
Postdoctoral Fellow 1 one year of Postdoc experience
Postdoctoral Fellow 2  two years of experience
Postdoctoral Fellow 3  three years of postdoc experience
Postdoctoral Fellow 4  four years of postdoc experience

Not applicable

Experience in biomedical research required.