ASSOCIATE SCIENTIST – CANCER IMMUNOLOGY
May 22, 2018 - June 23, 2018
In addition, Neon has established strategic partners in BMS, Merck, and Apexigen to harness opportunities for combination therapies. Neon leverages foundational intellectual property from the Broad Institute and the Dana-Farber Cancer Institute.Neon Therapeutics was incubated and launched by Third Rock Ventures and raised a $55M Series A in 2015 and, more recently, a $106M Series B in 2017.
Position Summary
The successful candidate will work in the Neon SELECT program that aims to develop therapies against neoantigen targets shared across patients. S/he will focus on generating and studying T cell responses to shared neoantigens, with particular focus on peptide design and T cell receptor characterization. The candidate will need to work on a team but also independently test many different technologies. S/he will need to work effectively on a team while also independently perform cell and molecular biology assays. The candidate will work closely with the departments of T cell immunology, molecular immunology, peptide chemistry, and bioinformatics.
Job Responsibilities:
- Culture and manipulation of human T cells
- Assessment and analysis of specificity of human T cells by multicolor flow cytometry
- Perform scRNA and TCR sequencing as well as data analysis
- Design and analysis of immunogenic peptide sequences
- Production of stable cell lines using transfection or transduction
- Analysis and presentation of results to larger scientific groups
- Assist with the training of lab personnel
- Work productively in a team environment and independently and deliver against timelines.
Experience and essential skills:
- M.S. with 5-8 years of experience, or Ph.D. with 0-2 years of experience in industry with a strong background in immunology.
- A strong background in adaptive immunity in the context of cancer is preferred
- Demonstrated mastery of flow cytometry and related data analysis
- Experience with functional immune assays, such as cytokine analysis
- General molecular biology techniques, including plasmid cloning and preparation
- Experience with lentivirus preparation and infection
- Ability to organize and tabulate data.
- Strong evidence of leadership background and experience working in cross-functional teams
- Excellent and record-keeping skills.
- Strong written and oral communication skills.
- Independent, flexible, self-motivated.
To apply, please send your resume to careers@neontherapeutics.com