ROLE SUMMARY

We are seeking an Associate Scientist level to join the In Vivo Pharmacology Group within the Oncology Research Unit (ORU) of Pfizer’s Worldwide Research & Development (WRD) division in La Jolla, California. The successful candidate will join a dynamic team of scientists, playing a leading role in the characterization of models of cancer and evaluating new drug candidates. Participate in pre-clinical drug discovery and development projects with a focus on targeted therapeutics, epigenetics and the tumor microenvironment. Characterize and develop small molecules in close collaboration with partner lines as an integral member of drug discovery teams. Evaluate anti-tumor effects in combination with biologics, employ and develop new cutting-edge in vivo cancer models and provide technical and scientific expertise in in vivo pharmacology to the tumor cell biology department to enable target identification, validation, prioritization and efficient drug discovery of small molecules. 

Ideal applicants will have excellent communication and organizational skills, critical problem-solving abilities, and a commitment to excellence.

ROLE RESPONSIBILITIES:

• Assist/Conduct in vivo studies to evaluate and establish efficacy, PK/PD relationship, combination strategy, biomarker identification and analysis.
• Interpretation, presentation and documentation of experiments.
• Presentation of results within a multidisciplinary team environment.
• Regularly read scientific papers and implement learnings in the study designs or project strategies.

BASIC QUALIFICATIONS:

• Bachelor of Science degree in Cancer Biology, Immunology or related discipline.
• 0-3 years of laboratory work experience in academia or industry.
• Ability to follow novel scientific or technological developments, and to implement them in the laboratory. 
• Excellent written and oral communication and presentation skills.
• Strong ability to multi-task and work productively in a fast-paced, highly collaborative, and diverse team environment.
• Capability to contribute to a vivid and challenging intellectual environment.

PREFERRED QUALIFICATIONS:

• In vivo skills (IV, PO dosing), blood/tissue collections
• Experience with in vivo models
• Some ex vivo skills such as FACS or Western blot are a plus