In the Kriwacki lab we are passionate about understanding how phase separation drives the condensation of biomolecules to create liquid-like bodies that mediate diverse biological processes. Importantly, aberrant biomolecular condensation is associated with several devastating human diseases, such as cancer and neurodegeneration.  A new initiative in the laboratory addresses the role of aberrant phase separation as a driver in cancer and we seek an analytical, critical thinking, self-driven cell biologist to join our team. The Staff Scientist will be responsible for conducting cutting edge research on phase separation by cancer-associated proteins in cells and their effects on chromatin structure and function, contributing to the training of postdoctoral fellows and students, and coordinating collaborative efforts.

The ideal candidate will have:

• a PhD degree in Cell Biology, Epigenetics or related field
• a minimum of 5 years post-graduate experience with functional genomics methods (e.g., RNA-seq, CHIP-seq, 3C-based methods, etc.), tissue culture (primary and immortalized cell lines), fluorescence microscopy and quantitative image analysis
• project management experience
• scientific writing experience
• excellent organizational and communication skills
• prior experience with biomolecular condensates is highly desired, as also is experience with cellular models of cancer

To learn more about our work, follow these links:

How does the most common ALS mutation doom cells?

How do molecular partners form dynamic scaffolding for protein machinery?

Key inner control mechanism of cell’s “smart glue”

Protein glue that holds biomolecules within the nucleolus

• A Ph.D. in an appropriate scientific field is required

• A minimum of five (5) years of relevant and productive (combined) years postdoctoral research associate or five (5) years of combined academic experience at the postdoctoral level or above.