January 14 - February 15
RESEARCH SCIENTIST, Koch Institute (KI) for Integrative Cancer Research-J&J Lung Cancer Initiative Collaboration (multiple positions), to contribute to three KI laboratories involved in research regarding the discovery and development of therapeutics and diagnostics that may be useful treating, preventing, intercepting, and/or diagnosing diseases specifically focused on lung cancer. The Jacks Laboratory will focus on genetic and epigenetic changes accompanying and controlling lung cancer initiation and progression; developing vaccines for disease interception; and the role of inflammation, inflammatory cells, and specific inflammatory mediators in lung cancer development. The Bhatia Laboratory will focus on novel diagnostic and early detection technologies, including protease activity-based nanosensors and explore the utility of these technologies using human genomic data and genetically-engineered mouse models (GEMMs) of lung cancer to detect and stratify disease early enough for interception. The Irvine laboratory will focus on early interception using immunotherapy agents to detect and prophylactically protect from lung cancer and generate novel immune-based drugs and vaccine platforms, especially focused on Kras-mutant lung tumors. These will be tested initially in GEMM models. Will contribute to executing research aims; establishing research strategy; reporting; and planning and writing animal and other protocols, manuscripts, and reports.
REQUIRED: MD and/or Ph.D. in medicine and/or biomedical science; extensive knowledge of cancer biology and related fields; ability to conceptualize and write proposals and publishable manuscripts, evaluate and train junior researchers, innovate, and conduct research; meticulous attention to detail; strong organizational, documentation, interpersonal, and communication skills; comfort summarizing and reporting results; ability to work collaboratively, follow safety procedures, and maintain a safe work environment. Familiarity with physiology; cell and molecular biology; immunology; animal testing of biologics; materials science; and/or histological, biochemical, and mechanical analyses ideal. Job #15547
This is a one-year, term-limit appointment with an extension based on continued funding.