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A postdoctoral position is available in the lab of David MacPherson. The position will be funded by a newly awarded R01, with a focus on the role of key chromatin regulators in driving small cell lung cancer (SCLC), an aggressive neuroendocrine tumor type. Cell based screens, genetic mouse models and study of patient derived tumors and xenografts will be employed in the research project.  The position is ideally suited to candidates interested in understanding at a molecular level how perturbation of chromatin regulators promotes SCLC and also how mutations in chromatin regulators confer vulnerabilities that can be exploited in the design of more effective therapeutics for SCLC.

Candidates should have a PhD and/or MD, one or more first author publications, and experience in molecular and/or cell biology.  Expertise in chromatin biology, genomic analyses, mouse genetics, and/or experience with cell based functional screens would all be looked upon favorably.  Candidates should be independent but also highly collaborative.

At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first and largest cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network.