A postdoctoral position is available to work at the interface of cancer epigenetics and translational therapeutics for head and neck malignancies. The position will be supported by a new NIH R01 award and industry-sponsored agreements in the Division of Head and Neck Surgery at the University of Pennsylvania Perelman School of Medicine. Our research program aims to develop novel approaches to target the tumor cell fractions within individual cancers that are innately resistant to current therapies. Studies will emphasize molecular and functional definition of the epigenetically distinct cell states within a heterogeneous tumor that contribute to treatment failure. Work will rely upon advanced in vitro cancer models, patient-derived xenografts, and human tumor specimens. Significant prior experience in epigenetics, cancer biology, bioinformatics, stem cell biology, and/or biochemistry is desirable. Training and career development will also be supported by investigators in a P01-funded program in esophageal squamous cell carcinoma in the Division of Gastroenterology. Applicants authorized for employment in the United States are strongly preferred. However visa sponsorship may be considered for an exceptional foreign applicant with well-developed English writing ability. Interested individuals should send cover letter, CV, and detailed reference information, including most recent research supervisor, by e-mail to:

Devraj Basu, M.D, Ph.D., F.A.C.S.
Assistant Professor 
Department of Otorhinolaryngology-Head and Neck Surgery 
The University of Pennsylvania
3600 Spruce St., 5 Ravdin/Silverstein 
Philadelphia, PA 19104

email: devraj.basu@uphs.upenn.edu 
http://www.med.upenn.edu/apps/faculty/index.php/g275/p8137952