Molecular pathology is one of the linchpins of precision medicine. No longer can treatment decisions related to therapy selection be rendered solely on the basis of histopathological analyses, as genomic analyses of human cancers are resulting in the identification of the genetic determinants of tumourigenesis, cancer progression and therapy response. The pathologists’ role in the implementation [...]

The Gordon Research Seminar on Chromatin Structure and Function is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas. The inaugural 2018 Gordon Research Seminar in Chromatin Structure and Function is a meeting for young scientists and [...]

The 2018 Gordon Conference on Chromatin Structure and Function will bring together leading experts and newcomers to the field, to present and discuss their newest research on chromatin, its complex interactions, and its regulatory power in shaping genome architecture and function. Technologies to visualize and map chromatin at all levels are proceeding at a rapid [...]

The EMBL Transcription and Chromatin meeting has a long-standing tradition in shaping the field of transcriptional regulation. The meeting brings together leading experts covering all aspects of transcription from cis-regulatory function, long range regulation, 3-dimensional looping, the basal transcriptional machinery, RNA polymerase regulation and function, nucleosome positioning, chromatin modifications, chromatin remodeling, and epigenetic inheritance of [...]

You are cordially invited to participate in the fourth Cold Spring Harbor Laboratory meeting on Epigenetics & Chromatin. The opening session will begin at 7:30 pm on Tuesday, September 11 and the meeting will end after lunch on Saturday, September 15, 2018. As currently planned, the program will have eight sessions devoted to oral presentations, together with three poster [...]

This FASEB SRC is designed to highlight the major advances in science and integrate different topics, which are part of an extremely fast-moving and exciting field of research. The biological scope and the mechanisms of action of DNA and RNA molecules, which have roles in dosage compensation, imprinting, enhancer function and transcriptional regulation, have a [...]

Before the genetic information stored in DNA can be used to direct cell growth and metabolism, it has to be transferred into RNA.  Messenger RNAs (mRNAs) that code for  proteins and noncoding RNAs are key components in the transmission of genetic information in all life forms - from viruses to complex mammalian organisms. Exciting recent [...]

Overview This exciting four-day conference at the beautiful luxury oceanfront Meliá Nassau Beach all inclusive resort in Nassau, Bahamas will highlight recent breakthroughs in epigenetics and chromatin research and will foster the collaboration and exchange of scientific expertise and knowledge in one of the most vibrant areas of life sciences. Through scientific presentations, a wide spectrum of topics [...]

Although emerging evidence point to the critical importance of the long non-coding transcriptome in human physiology and pathology, the clinical potential of long non-coding RNAs (lncRNAs) as therapeutic and prognostic targets remain largely unexplored. The increasing availability of high throughput technologies and newly developed computational methodologies are rapidly making it possible to address this gap [...]

Epigenetics is a major mechanism in human health and disease. Data from a range of diseases (cancer, neurological and immunological disorders) have uncovered altered epigenomes arising from mutations, altered expression and/or copy number alterations of numerous epigenetic factors (histones, DNA and chromatin modifying enzymes, reader proteins, chromatin modulators and noncoding RNAs). Genome-wide analyses have illustrated [...]

Conference Overview Epigenetics refers to heritable change in gene expression that does not involve changes to the underlying DNA sequence. At least three systems including DNA methylation, histone modifications and non-coding RNAs (ncRNA) are considered to play fundamental roles in epigenetic regulation. Research over the last two decades has uncovered the role of epigenetics in [...]

ESMO is delighted to announce that the ESMO 2019 annual Congress will take place in partnership with the European Association for Cancer Research (EACR) from 27 September to 1 October 2019, at the Fira Barcelona, Spain. The ESMO Congress is the appointment in Europe for clinicians, researchers, patient advocates, journalists and the pharmaceutical industry from all over the [...]

Discussing the future of epigenomic studies of common diseases We are pleased to announce the 8th Epigenomics of Common Diseases conference and invite scientists working on experimental and computational epigenomics and epigenetics to showcase the latest developments in the field and discuss epigenomic approaches in common human diseases. Epigenetic variation plays an important role in [...]

Symposium Overview Metabolism and epigenetics are intricately linked, playing a key role in development, cancer, immune signalling and ageing. This symposium brings together world-leading researchers exploring this nexus and will focus in particular on how metabolites and metabolic networks impact gene regulation, on recently discovered roles of metabolites in disease and how this opens novel [...]