The Espinosa Laboratory in the Cancer Division of the Department of Pharmacology at the University of Colorado Denver | Anschutz Medical Campus is seeking independent and creative postdoctoral fellows. The Espinosa Lab utilizes an integrated system of functional genomics and mechanistic studies aimed at making biological discoveries with clear translational potential. Most of our current [...]
Dr. Roberts’ lab studies the epigenetic regulation of gene expression. In particular we are studying chromatin-modifying proteins with a major focus on the SWI/SNF (BAF) chromatin remodeling/tumor suppressor complex and its relationship to cancers. Recent studies have revealed that genes encoding subunits of the SWI/SNF complex are mutated in over 20% of all cancers, a [...]
The successful candidate will study the roles of epigenetic regulation and the p53 signaling pathway in mouse embryonic stem cells using CRISPR-Cas9 screening. The overarching goal of this project is to understand how the p53 signaling pathways maintains the genomic stability of embryonic stem cells. Number of Positions: 1 C.V. Required: Yes Number of References [...]
