A Bioinformatics Research Scientist position is available in the lab of Dr. Charles Mullighan, MBBS (Hons), MSc, MD. This position offers an unrivaled opportunity to be embedded in an environment leading integrated genomic and experimental studies in Leukemia. As part of our laboratory, you will be involved in the integrative analysis of large cancer genomic datasets from patients with acute leukemia and related disorders. This involves the mapping and variant identification from large whole genome, exome and transcriptome sequencing datasets, and integration of such data to classify disease and predict outcome. Additional areas of work involve the analysis of epigenetic and ChIP sequencing data, and analysis of clonal evolution in cancer. The data are derived from the largest ALL datasets from the St Jude Pediatric Cancer Genome Project, the NCI TARGET initiative and projects initiated by Dr Mullighan.Candidates with deep understanding of cancer genomics, genetics or epigenetics, strong problem solving skills and expertise in next-generation sequencing data analysis are highly encouraged to apply.

Ph.D. in molecular biology, biochemistry, computer science, statistics, mathematics, bioinformatics or related field required

Ph.D which must include research related to bioinformatics (such as analysis of sequence data, microarrays, SNPs, image data, proteomics data, or biological pathways; development of algorithms, statistical methods, or scientific software); OR If Ph.D with no bioinformatics research, then two years of pre-or postdoctoral experience in computational biology or bioinformatics research is required

Experience with programming languages such as Perl, C, or Java required

Experience and knowledge on statistical analysis package such as R, SAS and Matlab is highly desired.