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An individual is sought to independently direct a project investigating molecular cross-talk between epigenetics and chromatin organization in normal and malignant hematopoiesis using molecular biology, biochemistry, fluorescence microscopy, and NGS-based epigenome profiling methods. The goal of these studies is to identify novel targets and design therapeutic interventions to prevent or delay the development of, and to treat acute myeloid leukemia. 

  • Design and coordinate projects to carry out experiments in animal models of myeloid malignancies and pre-leukemic conditions to evaluate potential therapeutic agents
  • Perform epigenomic and chromatin profiling experiments such as ChIP-seq, ATAC-seq, MAPit-PATCH, WGBS
  • Use wide field fluorescence and and confocal microscopy to document dynamic changes in chromatin structure in live and fixed hematopoietic cells
  • Analyze, interpret, and visually organize data
  • Write manuscripts
  • Assist with grant proposal preparation
  • Write technical reports
  • Train and supervise technical personnel, assist with mentoring of graduate students
  • Present research results at meetings

Advertised Salary: 
Commensurate with education and experience 

Minimum Requirements: 
Ph.D. in molecular biology, biochemistry, cancer biology, molecular genetics, or related field 

Preferred Qualifications: 
5+ years of research experience 

Expertise in cancer epigenetics, chromatin biology, transcriptomics, functional genomics, and other NGS-based methods as demonstrated by published papers in peer reviewed scientific journals 

Special Instructions to Applicants: 
Interested candidates must apply online. Please upload most recent CV, Cover Letter of interest, and three references with contact information.