Position Highlights: Characterize and Develop Next Generation Therapeutics for Lethal Prostate and Breast Cancers Project 1: To characterize epigenetic regulators promoting survival, adaptability and metastasis of lethal cancers, particularly hormone refractory prostate and breast cancers and characterize novel small molecule inhibitors that we have recently developed. Project II. To characterize novel epigenetic regulators of genome [...]
A Postdoctoral Fellow position is available in Dr. Chuong Dinh Hoang's laboratory within the Thoracic and Gastrointestinal Oncology Branch (TGIB) , National Cancer Institute, NIH. Our broad goal is to explore the molecular and cellular biology of thoracic cancers, namely mesothelioma and/ or non-small cell lung carcinoma, thymoma, etc. Currently, we have projects that involve [...]
Position Summary and Key Responsibilities: Postdoctoral position: Characterizing cancer progression and metastasis To develop and characterize solid cancer model systems in order to study epigenetic changes contributing to cancer progression and metastasis. These models will aid in the discovery of promising targets and evaluation of treatment strategies. The overall goal of these pre-clinical studies will be [...]
Postdoctoral positions are available in the Department of Cancer Biology to understand the biology of cancer stem cells, cancer progression and metastasis. We use molecular biology, biochemical and mouse modeling approaches to dissect the role of posttranslational modifications, such as protein ubiquitination and methylation in signaling pathways, metabolism, cancer immunity, epigenetics and DNA damage response [...]
1. Basic Cancer Research: We seek junior and senior investigators with innovative basic cancer biology programs that emphasize mechanistic approaches. Areas of interest include signal transduction, stem cells, gene regulation/transcription, chromatin/epigenetics, genome stability/DNAÂ repair, cancer metabolism, cancer genetics, metastasis, epithelial cancers, tumor immunology, hematologic malignancies, pediatric/youth cancers, and mechanisms of therapy resistance. Successful applicants will align [...]
The Laboratory of Cancer Biology and Genetics is seeking a postdoctoral fellow to conduct research in the Tumor Microenvironment and Metastasis Section. The research program focuses on the interplay of tumor and host in the metastatic process, and aims to identify critical molecular mediators for therapeutic target. The group utilizes a multi-disciplinary approach combining molecular, [...]
The lab is expanding their work on the molecular underpinnings of metastasis and are beginning to translate their findings into novel therapeutic approaches. Novel areas of interest include, but are not limited to, the role of epigenetics and metabolism in tumor progression and metastasis. We are also focused in understanding changes in transcriptome repertoire (coding and non-coding events) and [...]
Laboratory postdoctoral openings: • Studies on isoform-specific signaling by PI 3-kinase in tumor metastasis. Jonathan M. Backer, MD – Departments of Molecular Pharmacology and Biochemistry • Host-Microbe interactions, microbial genetics, metagenomics/metabolomics, inflammation and cancer. Sridhar Mani, MD – Departments of Genetics and Medicine • Studies on the pro-metastatic protein S100A4 in host-tumor cell interactions during [...]
Postdoctoral position: Characterizing cancer progression and metastasis To develop and characterize solid cancer model systems in order to study epigenetic changes contributing to cancer progression and metastasis. These models will aid in the discovery of promising targets and evaluation of treatment strategies. The overall goal of these pre-clinical studies will be to provide supporting data [...]
