Meeting Summary To maintain homeostasis, cells need to coordinate gene expression and metabolic state. There is increasing evidence that misregulation of metabolic flux and gene transcription plays a major role in human diseases, including obesity, diabetes and cancer. The aim of this meeting is to explore how metabolic state influences gene expression programs and, conversely, [...]

Meeting Summary Over the past decade, there has been a greater understanding of genomic complexity in eukaryotes ushered in by the immense technological advances in high-throughput sequencing of DNA and its corresponding RNA transcripts. This has resulted in the realization that beyond protein-coding genes, there are a large number of transcripts that do not encode [...]

This 2-day conference will focus on the study of epigenetic changes in normal and diseased cells in response to internal or external factors with the aim to translate basic epigenetic research into diagnosis, therapy and prevention.

Dear Colleagues, On behalf of the Organizing Committee, I am delighted to announce our International Symposium "Epigenetic Regulation of Skin Regeneration, Ageing and Disease", which we will organize in Bradford on March 17th-19th, 2016. Epigenetics Symposium Flyer The idea of the Symposium is to bring skin and chromatin biologists together and further promote the epigenetic [...]

Meeting Summary The DNA of eukaryotic cells is organized into chromatin fibers, where the nucleosome is the basic repeating unit. Chromatin is thus at the core of fundamental processes such as gene regulation, stem cell fate determination and cancer. By and large, these topics have traditionally been covered by separated meetings. However, recent literature indicates [...]

Targeting epigenetic modifiers and readers, particularly histone methyltransferases, demethylases and bromodomain-containing proteins have recently set the foundation for a new generation of anti-cancer drugs. Over the past few years, several companies have developed and successfully moved novel compounds targeting EZH2, DOT1L, LSD1, and a collection of BET bromodomain inhibitors into clinical studies. As these compounds [...]

The ‘Game of Epigenomics’ conference will celebrate the great diversity in the epigenomics field, reflecting both on DNA and protein modifications. The conference will host international and national leaders in the field, covering the spectrum of epigenomic research, presenting data from diverse model systems as well as clinical research and new insights in disease epigenomics. [...]

Meeting Summary Aging poses formidable scientific, medical and societal challenges. Old age is the single most important risk factor for a constellation of diseases, including cardiovascular disease, cancer, diabetes and a range of neurodegenerative disorders such as Alzheimer’s disease. Aging is also one of the greatest fundamental mysteries in biology, and arguably its next frontier. [...]

You are cordially invited to participate in the ninth meeting on Nuclear Organization and Function, which will be held at Cold Spring Harbor Laboratory. The meeting will begin on the evening of Tuesday, May 3, 2016, and will conclude with lunch on Saturday, May 7. The specific goal for this meeting is to bring together cellular [...]

We are pleased to announce the 4th Cold Spring Harbor Asia conference on Chromatin, Epigenetics and Transcription which will be held in Suzhou, China, located approximately 60 miles west of Shanghai. The conference will begin at 7:00pm on the evening of Monday May 9, and will conclude after lunch on May 13, 2016. The conference [...]

Meeting Description The 2016 Gordon Conference on Chromatin Structure and Function will present leading-edge research on chromatin and its role in regulating gene expression, genome function and cell states. The meeting will highlight how chromatin structures, ranging from the nucleosome – the "building block" of chromatin - up to the dynamic three-dimensional spatial organization of [...]

Welcome to the home page of the Wellcome Trust - Waddington Symposium Epigenetics in dialogue with THE GENOME The epigenetics field encompasses diverse opinions - even the definition of the word is controversial. How much our own make-up is genetic and what proportion of it is epigenetically determined is also hotly debated. Moreover, the ability [...]

We are pleased to host the 81st Cold Spring Harbor Symposium which will focus on Targeting Cancer. Implications of how the underlying science can drive improvements in diagnostic, prognostic and therapeutic approaches will be a major theme throughout the Symposium. The Symposium will begin at 7:30 pm on Wednesday June 1st, and end on the [...]

Join us! The 2016 Midwest Chromatin and Epigenetics Meeting (MCEM) will bring together more than 200 scientists from the American Midwest who study transcription, chromatin and epigenetics. The meeting provides an excellent opportunity to share scientific insight, foster the exchange of new ideas and to enhance collaboration. The meeting will be held from June 5–June [...]

Recent developments in sequencing technology have revealed widespread transcription of the eukaryotic genome, uncovering an overwhelming quantity of novel functional RNAs. The list of these RNAs is constantly increasing and already includes lncRNAs, circular RNAs and enhancer RNAs. The basic mechanisms of action of these RNAs remain to be elucidated and are most likely highly [...]