Position Highlights: Characterize and Develop Next Generation Therapeutics for Lethal Prostate and Breast Cancers Project 1: To characterize epigenetic regulators promoting survival, adaptability and metastasis of lethal cancers, particularly hormone refractory prostate and breast cancers and characterize novel small molecule inhibitors that we have recently developed. Project II. To characterize novel epigenetic regulators of genome [...]
Develop and drive tissue based biomarker assays including immunohistochemistry (IHC) and in-situ hybridization (ISH) biomarker assay development to support the AbbVie Oncology pipeline. Investigate, identify, develop, and optimize novel methods and techniques for tissue based biomarkers. Act as a lead scientist in his/her area of expertise and critically evaluate relevant scientific advances and integrate this [...]
The Principal Research Scientist applies extensive biology and drug development expertise to oversee cross-functionalresearch teams that are tasked with identifying and validating novel oncology targets, and then apply deep biology insights to then translate these finding to position novel oncology therapeutic agents in contexts that maximally benefit patients. The mission of The Center for Co-Clinical [...]
The H. Lee Moffitt Cancer Center and Research Institute (Moffitt) is seeking an outstanding investigator who is a leader in the Gastrointestinal (GI)Â cancer research field, and who will serve as Vice Chair of Research of the Gastrointestinal Oncology Department of Moffitt. The expertise of the Applicant should be evident in top-tier publications, extramural funding, an [...]
We seek a talented, collaborative inter-disciplinary scientist to lead innovative application of next-generation sequencing (NGS) methods in close collaboration with Celgene colleagues and strategic research & development partners. This individual will play a key scientific role in the development of internal sequencing resources and the optimization of Celgene NGS assays with focus on novel protocols [...]
Position Highlights: We seek highly motivated postdoctoral researchers to work on inter-disciplinary projects towards the characterization and inhibitor development of diverse kinases and bromodomain-containing proteins. The position provides exciting opportunities for biochemical, structural and cell-based studies of various drug-target interactions and rational drug design. The Ideal Candidate: The ideal candidate has a Ph.D. degree in [...]
The Arthanari Lab is seeking for a highly motivated postdoctoral candidate with expertise in transcriptional biology. Our laboratory works at the interface of structural biology, drug discovery and mechanistic biology, focusing on transcription factors and there interactions with co-activators and mediators (e.g. Nature. 201625;530(7591):485-9 ; Nature 2008. 452 (7187): 604-9) .Research efforts will be focused on the intersection [...]
The Pfizer Oncology Research & Development group in La Jolla is seeking a full-time employee to support the drug discovery process to create innovative cancer therapies. The successful candidate will provide expert scientific and technical expertise towards the discovery and pre-clinical development of innovative small molecule drugs for receptor-class protein targets (e.g. GPCR, NHR, SLC). [...]
Constellation Pharmaceuticals is a premier epigenetics company, focused on the discovery and development of novel, small molecules targeting chromatin regulatory proteins in tumor and immune cells for therapeutic applications in oncology. Our unique discovery platform integrates our understanding of chromatin-regulatory mechanisms with cancer and immune pathways to optimize our drug discovery activities and fully enable [...]
1. Basic Cancer Research: We seek junior and senior investigators with innovative basic cancer biology programs that emphasize mechanistic approaches. Areas of interest include signal transduction, stem cells, gene regulation/transcription, chromatin/epigenetics, genome stability/DNAÂ repair, cancer metabolism, cancer genetics, metastasis, epithelial cancers, tumor immunology, hematologic malignancies, pediatric/youth cancers, and mechanisms of therapy resistance. Successful applicants will align [...]
Merck Research Lab’s Oncology Discovery team is seeking a motivated, creative, and technically skilled student for a 3- month summer internship. The student should have a strong interest in cancer research and learning about oncology drug discovery. The successful candidate will serve as an integral member of a multidisciplinary drug discovery project team developing novel small molecule inhibitors [...]
Associate Computational Biologist The Kadoch Lab at the Dana-Farber Cancer Institute, Harvard Medical School and the Broad Institute focuses on cancer biology, epigenetics, and chromatin regulation. Our lab is uniquely centered at the intersection between biochemistry and functional studies of chromatin remodeling complexes, which are frequently mutated in human cancers. We seek a highly motivated [...]
The Institute Research Scientist participates in cross-functional research to identify and validate novel oncology targets, and applies deep biological insights to then translate these findings into novel oncology therapeutic agents to benefit patients. Salary Range: Min $95,000 - Mid $118,000 - Max $142,000 ESSENTIAL FUNCTIONS 1. Apply and develop basic science tools and methodologies to [...]
